Abstract P165: Urinary Amino Acid Profile And Cardiovascular Parameters In Overweight And Obese Brazilian Children

Hypertension ◽  
2021 ◽  
Vol 78 (Suppl_1) ◽  
Author(s):  
Mariana D Passadore ◽  
Nayara A Cruz ◽  
Mariana Z Bocato ◽  
Leonardo A Ferreira ◽  
Jose Geraldo Mill ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Amino Acids ◽  
Systolic Blood Pressure ◽  
Positive Association ◽  
Amino Acid Profile ◽  
Normal Weight ◽  
Creatinine Concentration ◽  
Cross Sectional ◽  
Cardiovascular Parameters ◽  
Urinary Amino

Despite being thoroughly studied, there isn’t complete elucidation of mechanisms underlying obesity, and especially regarding overweight in children. Small molecule metabolites are promising candidates for understanding obesity′s phenotypes. Recent metabolic studies have advanced in discovery of biomarkers for better knowledge of mechanisms related to obesity and its comorbidities. In this cross-sectional study it was evaluated the profile of urinary amino acids of 110 children that were classified in into groups of nutritional status according to their BMI/A (Body Mass Index/age), as normal weight (NW) (n=45), overweight (OW) (n=21) and obese (OB) (n=44). The 24h urine samples were submitted to LC-MS/MS for evaluation of 47 amino acids using Amino Acids Analysis Kit (Zivak®, Turkey), corrected by creatinine concentration. Biochemical profile, cardiovascular parameters and anthropometric measurements were assessed following standard protocols. Girls showed a higher heart rate (G: 82bpm vs B:79bpm, p=0,01 ) than boys. Increased weight presented higher values of systolic blood pressure ( NW: 102.0, OW: 109.0, OB: 110.0; NW vs OW, p = 0.0001; NW vs OB, p = 0.0001 ) and diastolic blood pressure ( NW: 60.0, OW: 67.0, OB: 66.75, NW vs OW, p < 0.0001; NW vs OB, p < 0.0001 ). The following amino acids (expressed in nmol/mg of creatinine) were found in higher concentrations in children’s urine with overweight or obesity, when compared with NW group, glutamine ( NW: 1024.3 vs OW: 1309.2, p=0.05), tryptophan (NW: 85.65, OW:113.55, OB:109.36; NW vs OW p=0.01; OW vs OB p=0.004), phenylalanine (NW: 43.04, OW:49.66, OB:72.08; NW vs OB p=0.01; OW vs OB p=0.04), and Tyrosine (NW: 85.07, OW: 109.74, OB: 140.54; NW vs OB p<0.01; OW vs OB p=0.04). In contrast, sarcosine had reduced concentrations for groups with weight excess (OW: 78.7 vs OB: 62.3, p=0.04). Urine levels of glutamine and aromatic amino acids were higher in OW and OB groups. Tyrosine also showed a positive association with systolic blood pressure values. Thus, there was a positive correlation between levels of glutamine and aromatics amino acids and excess weight, suggesting that they may be candidates to biomarkers for obesity in children. Furthermore, obesity was directly related to increase in blood pressure values.

scholarly journals Association of Serum Magnesium with Blood Pressure in Patients with Hypertensive Crises: A Retrospective Cross-Sectional Study

Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4213
Author(s):  
IfeanyiChukwu O. Onor ◽  
Lashira M. Hill ◽  
Modupe M. Famodimu ◽  
Mallory R. Coleman ◽  
Carolkim H. Huynh ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Primary Outcome ◽  
Serum Magnesium ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Hypertensive Crises

The role of magnesium in blood pressure has been studied among hypertensive patients; however, there is a dearth of studies exploring the role of magnesium in hypertensive crises. The primary objective of this study was to evaluate the relationship between serum magnesium and blood pressure in patients with hypertensive crises. This was a single-center, retrospective, chart review, cross-sectional study of patients with hypertensive crises. Patients were included if they were eighteen years of age or older, with an international classification disease ninth revision (ICD-9) code of 401.9 (hypertensive crises: emergency or urgency) and a documented magnesium level on their electronic medical record. The primary outcome of the study was the correlation between serum magnesium and blood pressure (systolic blood pressure and diastolic blood pressure) in patients with hypertensive crises. Two hundred and ninety-three patients were included in the study. The primary outcome result showed that serum magnesium was positively correlated with systolic blood pressure (r = 0.143, p = 0.014), but not diastolic blood pressure. Conclusion: This study found a significant positive association between magnesium and systolic blood pressure, but not diastolic blood pressure, among patients with hypertensive crises. This positive association of serum magnesium with systolic blood pressure was maintained after adjusting for covariates. This study’s findings suggest a potential role of magnesium in blood pressure among patients with hypertensive crises.

scholarly journals Hypertension and Obesity: A Cross-Sectional Study

2021 ◽  
Vol 3 (4) ◽  
pp. 90-94
Author(s):  
Jehanzeb Akram ◽  
Hafiz Raza Rehman ◽  
Fahad Muneer ◽  
Sarmad Hassan ◽  
Rida Fatima ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Weight Status ◽  
Mean Value ◽  
Normal Weight ◽  
Cross Sectional ◽  
P Values ◽  
Mean Values ◽  
High Prevalence

Hypertension is a common health issue all over the world. It has been suggested that hypertension leads to diseases of vital organs like, heart, brain, and kidney. Although, hypertension is under the influence of many factors like age, gender, marital status, genetic, social class, educational status, diabetes, lifestyle, and tobacco and alcohol consumption, even so, obesity is considered as a very critical factor. Thus, our study was established with the objective to determine interrelation between hypertension and obesity. This study with cross-sectional design was accomplished among general and regional population of Pak Arab society, Lahore in about 2months from March 2021 to the end of April 2021. People were called up in our study via established criteria. Data was collected by self-designed proforma and WHO classification was applied to classify participants into four WHO classes of weight status. Data analysis was done by applying SPSS version 25. Diverse statistical tests like Chi-square test, independent sample t-test, and One-Way-ANOVA test. were used to evaluate study variables. This study shows overall high prevalence of both hypertension (45.1%) and obesity (30.70%) among study population. Mean values of both blood pressures systolic and diastolic were higher among men (systolic blood pressure = 142.34 mmHg with SD of ±18.03, diastolic blood pressure = 89.93 mmHg with SD of ±1.26), than women (systolic blood pressure = 136.64 mmHg with SD of ±19.95, diastolic blood pressure = 89.65 mmHg with SD of ±8.67) however, these differences were not significant statistically with p-values 0.75 and 0.851 respectively. BMI mean values were higher among women (25.95 with SD of ±3.67) than men (25.76 with SD of ±4.10)), and difference was insignificant statistically (p=0.779). Variation in mean BMI values across four weight statuses (For Underweight BMI mean value = 17.86 with SD of ±0.38, for normal weight BMI mean value=21.18 with SD of ±1.36, for overweight BMI mean value =25.48 with SD of ±1.10, for obese BMI mean value= 30.47 with SD of ±0.77) was significant(p=0.0003). Difference in BMI mean values was also significant between hypertensive (BMI=27.68 with SD of ±3.28) and normotensive people (BMI= 24.39 with SD of ±3.62) with p-value of 0.0001. Variations in mean values of both systolic (underweight=127.57mmHg with SD of ±10.67, normal weight=126.89mmHg with SD of ±9.63, over weight=135.52mmHg with SD of ±17.46, obese=152.6mmHg with SD of ±19.74) and diastolic blood (underweight= 81.71mmHg with SD of ±7.29, normal weight=83.21mmHg with SD of ±4.68, over weight=89.39 mmHg with SD of ±7.57 , obese = 95.40 mmHg with SD of ±9.75) pressures across four statuses were significant with p values 0.004 and 0.0001 respectively. Gender was associated with weight status significantly (p=0.040); however, gender was not associated with hypertension (p=0.072) Most importantly, obesity and hypertension were associated significantly(p=0.0003) In summary, our study shows high prevalence of hypertension and obesity among enrolled population. Hypertension incidence goes up with increase in the weight. Hypertension incidence was higher among men than women whereas, obesity was higher among women than men. Thus, we can by controlling obesity we would be able to manage hypertension.

INTERARM SYSTOLIC BLOOD PRESSURE DIFFERENCE IS ASSOCIATED WITH A HIGH PREVALENCE OF CARDIO VASCULAR DISEASES- A CROSS-SECTIONAL STUDY IN POLICE WORKER

2020 ◽  
Vol 4 (11) ◽  
Author(s):  
Somesh Raju ◽  
Rina Kumari ◽  
Sunita Tiwari ◽  
NS Verma
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Blood Sugar ◽  
Pressure Difference ◽  
Systolic Pressure ◽  
Working Environment ◽  
Vascular Events ◽  
Cross Sectional ◽  
Blood Pressure Difference ◽  
High Prevalence

Background: Interarm systolic blood pressure difference more than 10 mm of Hg is predictor of cardiovascular and metabolic risk. Despite of sufficient physical activity there is high prevalence of obesity in police personal because of stressful working environment. No studies have addressed the significance of interarm pressure difference among them. Therefore, the present study conducted to access the relation of interarm blood pressure difference with obesity in police personnel. Aims and Objective: To estimate the interarm pressure difference in police personal to see its association with their obesity. Material and Method: This cross-sectional observational study done on 245 police workers in PAC, Sitapur, India. Subjects having more than ten years of working experience were included in study. Anthropometric measurements of subject recorded by following standard protocol. Measurement of systolic pressure in both arm recorded simultaneously by mercury sphygmomanometer. Available data analyze and expressed in percentage, mean with SD and chi square test to see the significance of association. Results: According to anthropometric results of subjects 77.14 prcent subjects were having generalised obesity and 82.04 percent of subjects having abdominal obesity. 34.29 percent of subjects showed abnormally high (?10 mmHg) inter-arm systolic blood pressure difference. Both type of obesity showed positive association with blood sugar level but no association with interarm pressure difference. Conclusion: Interarm blood pressure difference is greater in individual having obesity or prolong duration of service. Such subjects are more susceptible to develop coronary artery disease or peripheral arterial disease in future. Early screening can help to detect the vascular events likely to occur in the future Keywords: Body mass index, Waist circumference, Interarm pressure difference, Random blood sugar

scholarly journals Association between Blood Pressure and Serum Thyroid-Stimulating Hormone Concentration within the Reference Range: A Population-Based Study

2007 ◽  
Vol 92 (3) ◽  
pp. 841-845 ◽  
Author(s):  
Bjørn O. Åsvold ◽  
Trine Bjøro ◽  
Tom I. L. Nilsen ◽  
Lars J. Vatten
Keyword(s):  
Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Outcome Measures ◽  
Odds Ratio ◽  
Reference Range ◽  
Positive Association ◽  
Population Based ◽  
Thyroid Stimulating Hormone ◽  
Cross Sectional ◽  
Population Based Study

Abstract Context: The association between thyroid function and blood pressure is insufficiently studied. Objective: The objective of the investigation was to study the association between TSH within the reference range and blood pressure. Design and Setting: This was a cross-sectional, population-based study. Subjects: A total of 30,728 individuals without previously known thyroid disease were studied. Main Outcome Measures: The main outcome measures were mean systolic and diastolic blood pressure and pulse pressure and odds ratio for hypertension (&gt;140/90 mm Hg or current or previous use of antihypertensive medication), according to categories of TSH. Results: Within the reference range of TSH (0.50–3.5 mU/liter), there was a linear increase in blood pressure with increasing TSH. The average increase in systolic blood pressure was 2.0 mm Hg [95% confidence interval (CI) 1.4–2.6 mm Hg] per milliunit per liter increase in TSH among men, and 1.8 mm Hg (95% CI 1.4–2.3 mm Hg) in women. The corresponding increase in diastolic blood pressure was 1.6 mm Hg (95% CI 1.2–2.0 mm Hg) in men and 1.1 mm Hg (95% CI 0.8–1.3 mm Hg) in women. Comparing TSH of 3.0–3.5 mU/liter (upper part of the reference) with TSH of 0.50–0.99 mU/liter (lower part of the reference), the odds ratio for hypertension was 1.98 (95% CI 1.56–2.53) in men and 1.23 (95% CI 1.04–1.46) in women. Conclusion: Within the reference range of TSH, we found a linear positive association between TSH and systolic and diastolic blood pressure that may have long-term implications for cardiovascular health.

scholarly journals Bed-Based Ballistocardiography: Dataset and Ability to Track Cardiovascular Parameters

Sensors ◽  
2020 ◽  
Vol 21 (1) ◽  
pp. 156
Author(s):  
Charles Carlson ◽  
Vanessa-Rose Turpin ◽  
Ahmad Suliman ◽  
Carl Ade ◽  
Steve Warren ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Stroke Volume ◽  
Systolic Blood Pressure ◽  
Correlation Coefficient ◽  
Pearson Correlation ◽  
Health Assessment ◽  
Initial Study ◽  
Pearson Correlation Coefficient ◽  
Medical Systems ◽  
Cardiovascular Parameters

Background: The goal of this work was to create a sharable dataset of heart-driven signals, including ballistocardiograms (BCGs) and time-aligned electrocardiograms (ECGs), photoplethysmograms (PPGs), and blood pressure waveforms. Methods: A custom, bed-based ballistocardiographic system is described in detail. Affiliated cardiopulmonary signals are acquired using a GE Datex CardioCap 5 patient monitor (which collects ECG and PPG data) and a Finapres Medical Systems Finometer PRO (which provides continuous reconstructed brachial artery pressure waveforms and derived cardiovascular parameters). Results: Data were collected from 40 participants, 4 of whom had been or were currently diagnosed with a heart condition at the time they enrolled in the study. An investigation revealed that features extracted from a BCG could be used to track changes in systolic blood pressure (Pearson correlation coefficient of 0.54 +/− 0.15), dP/dtmax (Pearson correlation coefficient of 0.51 +/− 0.18), and stroke volume (Pearson correlation coefficient of 0.54 +/− 0.17). Conclusion: A collection of synchronized, heart-driven signals, including BCGs, ECGs, PPGs, and blood pressure waveforms, was acquired and made publicly available. An initial study indicated that bed-based ballistocardiography can be used to track beat-to-beat changes in systolic blood pressure and stroke volume. Significance: To the best of the authors’ knowledge, no other database that includes time-aligned ECG, PPG, BCG, and continuous blood pressure data is available to the public. This dataset could be used by other researchers for algorithm testing and development in this fast-growing field of health assessment, without requiring these individuals to invest considerable time and resources into hardware development and data collection.

scholarly journals Biomarker-estimated flavan-3-ol intake is associated with lower blood pressure in cross-sectional analysis in EPIC Norfolk

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Javier I. Ottaviani ◽  
Abigail Britten ◽  
Debora Lucarelli ◽  
Robert Luben ◽  
Angela A. Mulligan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Vascular Function ◽  
Cardiovascular Health ◽  
Vascular Diseases ◽  
Inverse Association ◽  
Cvd Risk ◽  
Lower Systolic Blood Pressure ◽  
Cross Sectional ◽  
Salt Reduction

Abstract Flavan-3-ols are a group of bioactive compounds that have been shown to improve vascular function in intervention studies. They are therefore of great interest for the development of dietary recommendation for the prevention of cardio-vascular diseases. However, there are currently no reliable data from observational studies, as the high variability in the flavan-3-ol content of food makes it difficult to estimate actual intake without nutritional biomarkers. In this study, we investigated cross-sectional associations between biomarker-estimated flavan-3-ol intake and blood pressure and other CVD risk markers, as well as longitudinal associations with CVD risk in 25,618 participants of the European Prospective Investigation into Cancer (EPIC) Norfolk cohort. High flavan-3-ol intake, achievable as part of an habitual diet, was associated with a significantly lower systolic blood pressure (− 1.9 (− 2.7; − 1.1) mmHg in men and − 2.5 (− 3.3; − 1.8) mmHg in women; lowest vs highest decile of biomarker), comparable to adherence to a Mediterranean Diet or moderate salt reduction. Subgroup analyses showed that hypertensive participants had stronger inverse association between flavan-3-ol biomarker and systolic blood pressure when compared to normotensive participants. Flavanol intake could therefore have a role in the maintenance of cardiovascular health on a population scale.

What Physical Fitness Component Is Most Closely Associated With Adolescents' Blood Pressure?

2017 ◽  
Vol 124 (6) ◽  
pp. 1107-1120 ◽  
Author(s):  
Heloyse E. G. Nunes ◽  
Carlos A. S. Alves ◽  
Eliane C. A. Gonçalves ◽  
Diego A. S. Silva
Keyword(s):  
Blood Pressure ◽  
Body Composition ◽  
Muscle Strength ◽  
Physical Fitness ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Aerobic Fitness ◽  
Pressure Control ◽  
Cross Sectional ◽  
Digital Pressure

This study aimed to determine which of four selected physical fitness variables, would be most associated with blood pressure changes (systolic and diastolic) in a large sample of adolescents. This was a descriptive and cross-sectional, epidemiological study of 1,117 adolescents aged 14–19 years from southern Brazil. Systolic and diastolic blood pressure were measured by a digital pressure device, and the selected physical fitness variables were body composition (body mass index), flexibility (sit-and-reach test), muscle strength/resistance (manual dynamometer), and aerobic fitness (Modified Canadian Aerobic Fitness Test). Simple and multiple linear regression analyses revealed that aerobic fitness and muscle strength/resistance best explained variations in systolic blood pressure for boys (17.3% and 7.4% of variance) and girls (7.4% of variance). Aerobic fitness, body composition, and muscle strength/resistance are all important indicators of blood pressure control, but aerobic fitness was a stronger predictor of systolic blood pressure in boys and of diastolic blood pressure in both sexes.

scholarly journals Konsumsi makanan tinggi natrium, kesukaan rasa asin, berat badan, dan tekanan darah pada anak sekolah

2016 ◽  
Vol 12 (3) ◽  
pp. 89
Author(s):  
Heni Hendriyani ◽  
Enik Sulistyowati ◽  
Astidio Noviardhi
Keyword(s):  
Blood Pressure ◽  
Food Consumption ◽  
Junior High School ◽  
Later Life ◽  
Normal Weight ◽  
Bivariate Analysis ◽  
Chi Square ◽  
Cross Sectional ◽  
Level Data ◽  
Cross Sectional Design

Background: It is a fact that natrium consumption relates to hypertension and the risk of heart disease and stroke. Even though it is common happened in later life, hypertension can be started in early age.Objective: The aim of the study is to identify salty food preference, high natrium food consumption, natrium intake, weight and its correlation with blood pressure among schoolchildren.Method: The study used cross-sectional design. There were 151 samples from junior high school chosen by purposive sampling. Food salty level data was assessed by eating the snack with three different salt concentration. High and low natrium source food and natrium intake data were taken using semi-quantitative food frequency questionnaire. Blood pressure was measured by sphygmomanometer digital. Bivariate analysis was used Chi-square and Rank Spearman test.Results: The study revealed that 74,2% children prefer snack with the salt level above recommendation (> 0,5 gr salt per portion ). There were 22,5% children have natrium intake from food only ≥2000 mg (above recommendation). As much as 35,8% children fall into hypertension category based on their blood pressure (BP) level. There was a significant relationship between high natrium food consumption score with natrium intake (p=0,002). There were significant correlation between weight with systolic and diastolic BP ((p=0,000 r=-0,549 and p=0,000 r=-0,412). There were no correlation between atrium intake with systolic and diastolic BP (p=0,764;  r= 0,0025 and p=0,819 r=0,19).Conclusion: Healthy food and maintaining normal weight information and education must be done for children as early as possible.

scholarly journals HUBUNGAN INDEKSMASSA TUBUH DAN LINGKAR PINGGANG DENGAN TEKANAN DARAH LAKI-LAKI DEWASA

2018 ◽  
Vol 9 (2) ◽  
pp. 193-199
Author(s):  
Tamariani Manullang
Keyword(s):  
Blood Pressure ◽  
Waist Circumference ◽  
Systolic Blood Pressure ◽  
Study Design ◽  
Computer Software ◽  
Adult Males ◽  
Cross Sectional ◽  
Relationship Of ◽  
The Relationship

Prevalence of hypertension in adult males was highest in PuskesmasBasuki Rahmat (16.2%) as many as 648 cases of hypertension patients which hasincreased compared to 2012 by 12% in cases of hypertension totaled 482 patients((Dinkes Kota, 2013). This study aims to determine the relationship of body massindex (BMI) and waist circumference (WC) with systolic blood pressure (BP) in adultmales in Puskesmas Basuki Rahmat Bengkulu City in 2015. The study design wasdescriptive analytic with cross sectional approach. Study location was in PuskesmasBasuki Rahmat City of Bengkulu. Samples were selected using purposive samplingtotalling 68 people. Criterias sample were being adult males who occupied inPuskesmas Basuki Rahmat City of Bengkulu, aged ≥ 18 years, agreed to beinterviewed,and able to communicate actively. Data were obtained include BMI, WCand systolic BP adult males and processed using computer software with pearsoncorrelation analysis.The results showed that there was relationship between BMI andsystolic BP (p = 0.0005; r = 0.395); between WC and systolic BP (p = 0.004 and r =0.347) in adult males. This study concluded that there was relationship between BMIand WC with systolic BP in adult males in Puskesmas Basuki Rahmat Bengkulu Cityin 2015.

scholarly journals Synergistic Impact of Systolic Blood Pressure and Perfusion Status on Mortality in Acute Heart Failure

2021 ◽  
Vol 14 (3) ◽  
Author(s):  
Xavier Rossello ◽  
Héctor Bueno ◽  
Víctor Gil ◽  
Javier Jacob ◽  
Francisco Javier Martín-Sánchez ◽  
...  
Keyword(s):  
Heart Failure ◽  
Blood Pressure ◽  
Physical Examination ◽  
Systolic Blood Pressure ◽  
Acute Heart Failure ◽  
Positive Association ◽  
Prognostic Impact ◽  
Inverse Association ◽  
Logistic Regression Models ◽  
Short Term Mortality

Background: Physical examination remains the cornerstone in the assessment of acute heart failure. There is a lack of adequately powered studies assessing the combined impact of both systolic blood pressure (SBP) and hypoperfusion on short-term mortality. Methods: Patients with acute heart failure from 41 Spanish emergency departments were recruited consecutively in 3 time periods between 2011 and 2016. Logistic regression models were used to assess the association of 30-day mortality with SBP (<90, 90–109, 110–129, and ≥130 mm Hg) and with manifestations of hypoperfusion (cold skin, cutaneous pallor, delayed capillary refill, livedo reticularis, and mental confusion) at admission. Results: Among 10 979 patients, 1143 died within the first 30 days (10.2%). There was an inverse association between 30-day mortality and initial SBP (35.4%, 18.9%, 12.4%, and 7.5% for SBP<90, SBP 90–109, SBP 110–129, and SBP≥130 mm Hg, respectively; P <0.001) and a positive association with hypoperfusion (8.0%, 14.8%, and 27.6% for those with none, 1, ≥2 signs/symptoms of hypoperfusion, respectively; P <0.001). After adjustment for 11 risk factors, the prognostic impact of hypoperfusion on 30-day mortality varied across SBP categories: SBP≥130 mm Hg (odds ratio [OR]=1.03 [95% CI, 0.77–1.36] and OR=1.18 [95% CI, 0.86–1.62] for 1 and ≥2 compared with 0 manifestations of hypoperfusion), SBP 110 to 129 mm Hg (OR=1.23 [95% CI, 0.86–1.77] and OR=2.18 [95% CI, 1.44–3.31], respectively), SBP 90 to 109 mm Hg (OR=1.29 [95% CI, 0.79–2.10] and OR=2.24 [95% CI, 1.36–3.66], respectively), and SBP<90 mm Hg (OR=1.34 [95% CI, 0.45–4.01] and OR=3.22 [95% CI, 1.30–7.97], respectively); P -for-interaction =0.043. Conclusions: Hypoperfusion confers an incremental risk of 30-day all-cause mortality not only in patients with low SBP but also in normotensive patients. On admission, physical examination plays a major role in determining prognosis in patients with acute heart failure.

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