Abstract WMP82: The Association Between Cerebral Microbleeds And Arterial Stiffness

Background and significance: Increased arterial stiffness causes vessel damage of the end-organs. Thus, in the brain, small vessels may be susceptible to increased arterial stiffness. Cerebral microbleeds (CMBs) are topographically categorized as non-lobar type, mostly due to hypertensive vasculopathy and lobar type, due to cerebral amyloid angiopathy. When considering CMBs in the nonlobar region are associated with small vessel pathology, arterial stiffness may be related with CMBs in the nonlobar region. We investigated relationship between CMBs by using brachial ankle pulse wave velocity (baPWV) representing arterial stiffness. Method: Between June 2006 and January 2012, we included 1290 consecutive patients with acute ischemic stroke admitted to hospital within 7 days after symptom onset and who underwent baPWV and brain gradient echo (GRE) and Fluid Attenuated Inversion Recovery (FLAIR) MRI. Patients with potential cardiac sources of embolism or peripheral arterial occlusive disease were not included. BaPWV was measured during ankle-brachial index examination using an automatic device. CMBs were classified as lobar and nonlobar type. Severity of leukoaraiosis was determined using the Fazekas’ scoring system. Binary and multinomial logistic regression analyses were performed to determine variables that were associated with presence and location of CMBs. Results: Mean age of the patients was 64±12 years and 61.9% (799/1290) were male. Of 1290 patients, CMBs were found in 28.6%. The patients with CMBs were older than those without CMBs (69±10 years versus 63±12 years, p=0.001). Mean baPWV was higher in patients with CMBs than those without (2240±512cm/s versus 1896±505cm/s, p=0.001). On multivariate binary logistic analysis, baPWV and high grade leukoaraiosis were independent predictors of the presence of CMBs. However, after adjustment of age, sex and variables with p value of less than 0.1on the univariate analysis, baPWV was independently associated with nonlobar CMBs. Conclusion: Arterial stiffness was independently associated with nonlobar CMBs but not with lobar CMBs. These findings suggest pathophysiologic association between arterial stiffness and CMBs in the nonlobar region.

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AB0132 THE STUDY OF SUBCLINICAL SYNOVITIS DETECTED BY ULTRASONOGRAPHY AND MRI IN RA PATIENTS AFTER REACHING CLINICAL REMISSION ON PATIENT’S SUBJECTIVE SYMPTOMS

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2021-eular.2830 ◽

2021 ◽

Vol 80 (Suppl 1) ◽

pp. 1094.2-1094

Author(s):

M. Nawata ◽

K. Someya ◽

T. Aritomi ◽

M. Funada ◽

K. Nakamura ◽

...

Keyword(s):

Clinical Remission ◽

Research Funding ◽

Morning Stiffness ◽

Univariate Analysis ◽

P Value ◽

Research Support ◽

Residual Symptoms ◽

Logistic Analysis ◽

Significant Difference ◽

Multivariate Logistic Analysis

Background:The goal of treatment in rheumatoid arthritis (RA) is to achieve remission. There is the patient with residual symptoms in the Japanese RA patient who achieved clinical remission. There are not many studies to examine the relation between everyday life, social activity and evaluation of disease activities using high-sensitivity image examinations (musculoskeletal ultrasound (MSKUS) and MRI).Objectives:To examine the relationship between subjective residual symptoms and imaging examinations in RA patients who have achieved clinical remission.Methods:30 RA patients who achieved SDAI remission during RA treatment. Age, sex, disease duration, physical findings, serological markers, disease activity, HAQ, EQ-5D-5L, FACIT-F, Patient Reported Outcomes (PROs), EGA and medications were evaluated. 44 joints were assessed by MSKUS with gray scale (GS) and power doppler (PD) and contrast-enhanced bilateral joint MRI scoring with OMERACT-RAMRIS scoring.Results:1. The mean SDAI of the 30 RA patients was 1.3. 2.In the analysis of the presence or absence of subjective residual symptoms that led to remission of SDAI (Table 1).Table 1.Subjective residual symptoms/presence (N=17)Subjective residual symptoms/absence (N=13)Univariate analysisp valueMultivariate logistic analysisp valueTJC0.0±0.00.3±0.50.0173HAQ0.4±0.40.05±0.10.00950.00181EQ5D-5L0.8±0.10.9±0.00.0001FACIT-F14.5±9.84.6±4.30.0233Morning stiffness (min)256.5±564.80.0±0.00.0210Pain (VAS) (mm)9.2±9.50.9±1.50.00440.0455PGA (mm)7.7±9.00.5±1.10.0013(1). In the univariate analysis, the number of tender joints, HAQ, EQ-5D-5L, FACIT-F, morning stiffness, and pain VAS were extracted with significant differences.(2). In multivariate logistic analysis, HAQ and pain VAS were extracted as independent factors with significant differences. 3.In univariate analysis of the association between HAQ and pain VAS extracted in multivariate logistic analysis and imaging examinations (MSKUS/MRI), MRI-synovitis was extracted with a significant difference in HAQ.Conclusion:1. It was suggested that Pain VAS and HAQ due to RA could be identified in patients reaching SDAI remission. 2. In patients reaching SDAI remission, Pain VAS ≤10 or HAQ ≤0.5 suggested that subjective residual symptoms may be eliminated. 3. HAQ ≤ 0.5 suggests that synovitis is less likely to be detected on MRI. 4. In patients who have reached SDAI remission, little residual inflammation was observed on US, suggesting that induction of remission is important not only to prevent joint destruction, but also to improve and maintain long-term QoL.Disclosure of Interests:MASAO NAWATA Grant/research support from: I have received research funding from Eli Lilly Japan K.K., Kazuki Someya: None declared, Takafumi Aritomi: None declared, Masashi funada: None declared, Katsumi Nakamura: None declared, SAITO KAZUYOSHI Grant/research support from: I have received research funding from Eli Lilly Japan K.K., Yoshiya Tanaka Speakers bureau: I have received speaking fees from Abbvie, Daiichi-Sankyo, Chugai, Takeda, Mitsubishi-Tanabe, Bristol-Myers, Astellas, Eisai, Janssen, Pfizer, Asahi-kasei, Eli Lilly, GlaxoSmithKline, UCB, Teijin, MSD, and Santen, Consultant of: I have received consulting fees from Abbvie, Daiichi-Sankyo, Chugai, Takeda, Mitsubishi-Tanabe, Bristol-Myers, Astellas, Eisai, Janssen, Pfizer, Asahi-kasei, Eli Lilly, GlaxoSmithKline, UCB, Teijin, MSD, and Santen, Grant/research support from: I have received research grants from Mitsubishi-Tanabe, Takeda, Chugai, Astellas, Eisai, Taisho-Toyama, Kyowa-Kirin, Abbvie, and Bristol-Myers

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To Determine the Relation Between Ankle-Brachial Index with Angiographic Stenosis and Major Cardiovascular Risk Factors In Patients With Suspected Coronary Artery Disease.

Journal of Medical Research and Innovation ◽

10.15419/jmri.138 ◽

2018 ◽

Vol 2 (S1) ◽

pp. e000138

Author(s):

Vivek Agarwal ◽

Tejas Patel ◽

Sanjay Shah

Keyword(s):

Coronary Artery Disease ◽

Heart Disease ◽

Coronary Artery ◽

Univariate Analysis ◽

Ankle Brachial Index ◽

Significant Coronary Artery Disease ◽

Limb Ischemia ◽

P Value ◽

Artery Disease ◽

The Relationship

Aims and Objectives: Prevalence of low Ankle-Brachial Index (ABI) in patients with Ischaemic Heart Disease. To compare the relationship between various physiological parameters like age, sex, and BMI with ABI. To compare the relationship between low ABI and number of coronaries involved. Methodology: Inclusion Criteria: All the 1423 patients aged 23-90 years including 1047 male and 376 female undergoing coronary angiography in VS hospital. Exclusion Criteria: Critically ill or who had severe limb ischemia or patients with amputation were excluded. Statistical analysis was done by using SPSS 20.0 version. Univariate analysis was performed by applying the Pearson chi-squared test. Results: In this study, 1423 patients were evaluated out of which 66 (4.6%) patients had ABI<0.9. Out of 66 patients with low ABI 60 (91%) were male and 6 (9%) were female, showing high prevalence in the male. In patients having low ABI shows 12 (18.2%) have SVD, 11(16.7%) have DVD, 26(39.4%) have TVD, comparing this with patients having normal ABI, shows P value of 0.035 which is significant. 411 patients were diabetic including 40 (60.6%) patients having low ABI and 371 (27.3%) patients having normal ABI, shows P value of 0.000 which is highly significant. Conclusion: ABI is helpful in identifying individuals at high risk of coronary involvement. Although the prevalence of low ABI in patients with IHD is 4.6% that is very low but is highly specific (91%). In patients with ischemic heart disease low ABI suggests the involvement of multivessel disease. Direct association between ABI and significant Coronary Artery Disease noted.

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Determinants of Arterial Stiffness in Female Patients with Takayasu Arteritis

The Journal of Rheumatology ◽

10.3899/jrheum.131110 ◽

2014 ◽

Vol 41 (7) ◽

pp. 1374-1378 ◽

Cited By ~ 6

Author(s):

Nilton Salles Rosa Neto ◽

Maurício Levy-Neto ◽

Elaine Cristina Tolezani ◽

Eloísa Bonfá ◽

Luiz Aparecido Bortolotto ◽

...

Keyword(s):

Blood Pressure ◽

Arterial Stiffness ◽

Takayasu Arteritis ◽

Characteristic Curve ◽

Univariate Analysis ◽

Receiver Operator Characteristic Curve ◽

Healthy Controls ◽

Average Systolic Blood Pressure ◽

Female Patients ◽

Logistic Analysis

Objective.The assessment of pulse wave velocity (PWV) in Takayasu arteritis (TA) is complex because of many confounding factors. We evaluated PWV in female patients with TA and controls with comparable anthropometric and clinical variables and assessed a possible association of TA with disease variables.Methods.We evaluated 27 patients with TA consecutively. Exclusion criteria were menopause, smoking, diabetes, renal insufficiency, poorly controlled hypertension, cardiac arrhythmias, obesity, inflammatory comorbidities, pregnancy, and surgical procedures involving the aorta. Disease activity was determined by clinical and laboratory variables. As healthy controls, 27 subjects with comparable age, blood pressure, height, and weight were selected. Carotid-femoral PWV measurements were obtained using the Complior system.Results.The mean PWV in patients with TA was higher than in healthy controls (9.77 ± 3.49 vs 7.83 ± 1.06 m/s; p = 0.009). Despite our strict selection criteria, patients with TA had an average systolic blood pressure (SBP) 8 mmHg higher than controls (p = NS), and significantly higher pulse pressure values. The multivariate linear regression model shows that 93.8% of the PWV variability is explained by the variables age, mean BP, and the disease itself (adjusted R2= 0.938). Stepwise logistic analysis using the PWV cutoff value established by the receiver-operator characteristic curve (> 8.34 m/s) as dependent variable, and measures with significance in univariate analysis as independent variables revealed that TA (OR 4.69; 95% CI 1.31–16.72; p = 0.017) and mean BP (OR 1.06; 95% CI 1.00–1.12; p = 0.048) were independently associated with higher PWV. Further analysis of disease variables revealed that PWV values were not correlated with erythrocyte sedimentation rate, C-reactive protein, cumulative dose of glucocorticoid, or ejection fraction (p > 0.05).Conclusion.In our cohort of female patients with TA, the disease itself and mean BP were the strongest determinants associated with arterial stiffness.

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High pulse wave velocity is associated with the severity of diabetic retinopathy in patients with type 2 diabetes

Journal of Investigative Medicine ◽

10.1136/jim-2019-001240 ◽

2020 ◽

Vol 68 (6) ◽

pp. 1159-1165

Author(s):

Sung-Chen Liu ◽

Shih-Ming Chuang ◽

Hong-Mou Shih ◽

Chao-Hung Wang ◽

Ming-Chieh Tsai ◽

...

Keyword(s):

Type 2 Diabetes ◽

Diabetic Retinopathy ◽

Arterial Stiffness ◽

Pulse Wave Velocity ◽

Wave Velocity ◽

Proliferative Diabetic Retinopathy ◽

Pulse Wave ◽

Multinomial Logistic Regression ◽

Univariate Analysis

Pulse wave velocity (PWV) is a non-invasive test for assessing arterial stiffness, and brachial-ankle PWV has been used as an index of peripheral arterial stiffness. This study aimed to investigate the association between the PWV value and severity of diabetic retinopathy (DR). 846 patients with type 2 diabetes (T2DM) consecutively underwent brachial-ankle PWV, and the degree of PWV was defined by tertile. The severity of DR was categorized as no diabetic retinopathy (NDR), non-proliferative diabetic retinopathy (NPDR) or proliferative diabetic retinopathy (PDR) based on the Early Treatment Diabetic Retinopathy Study Scale. Multinomial logistic regression analyses were utilized not only to explore the association between the degree of PWV and severity of DR but also to examine the association of a high-tertile PWV with PDR. PWV levels, diabetes duration and blood pressure were all significantly higher in subjects with NPDR or PDR as compared with individuals with NDR. In the univariate analysis, the highest tertile of PWV (>19.6 m/s) was significantly associated with both NPDR (p<0.001) and PDR (p<0.001) as compared with NDR. After adjusting for confounding factors, the highest tertile of PWV remained significantly associated with PDR (p=0.005), but not with NPDR (p=0.107). Furthermore, the highest tertile of PWV was more significantly associated with PDR (OR=6.15, 95%CI 1.38 to 27.38) as compared with the lowest tertile. In our study, an increasing degree of PWV was positively associated with the severity of DR. High PWV was strongly associated with the risk of severe DR, especially PDR.

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Abstract MP90: Carotid Arterial Stiffness is Associated with An Increased Risk of Incident Cerebral Microbleeds in Older People: the Age, Gene/Environment Susceptibility-Reykjavik Study

Circulation ◽

10.1161/circ.131.suppl_1.mp90 ◽

2015 ◽

Vol 131 (suppl_1) ◽

Author(s):

Jie Ding ◽

Michiel L Bots ◽

Sigurdur Sigurdsson ◽

Melissa Garcia ◽

Tamara B Harris ◽

...

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Arterial Stiffness ◽

Brain Mri ◽

Population Based ◽

Cerebral Microbleeds ◽

Amyloid Angiopathy ◽

Gene Environment ◽

Increased Risk ◽

Carotid Arterial

Introduction: Cerebral microbleeds (CMBs) resulting from cerebral amyloid angiopathy are predominantly located in lobar regions, whereas those from hypertension are in deep and infratentorial regions. Although age and high blood pressure are major risk factors for CMBs, the underlying mechanisms remain unclear; arterial stiffness may be important. Hypothesis: We hypothesized that carotid arterial stiffness, would be associated with incident CMBs. Given the spatial distributions of the underlying arteriopathies in which hypertensive arteriopathy typically affects the small perforating end-arteries of the deep structures, we further hypothesized that the associations would be more robust for deep CMBs attributed to hypertensive arteriopathy. Methods: In the prospective, population-based Age, Gene/Environment Susceptibility-Reykjavik Study, 2,512 participants aged 66-97 years underwent a baseline brain MRI examination and carotid ultrasound in 2002-2006, and returned for a repeat brain MRI in 2007-2011. Common carotid arterial stiffness was assessed using a standardized protocol and expressed as carotid arterial strain (CAS), distensibility coefficient (DC) and Young’s elastic modulus (YEM). Log-binomial regression was applied to relate carotid arterial stiffness parameters to CMBs incidence. Results: During a mean follow-up of 5.2 years, 463 people (18.4%) developed new CMBs, of whom 292 had CMBs restricted to lobar regions and 171 had CMBs in a deep or infratentorial region. After adjusting for age, sex and brain MRI interval, all arterial stiffness parameters were each significantly associated with incident CMBs (Risk ratio [RR] per SD decrease in CAS, 1.11 [95%CI, 1.02-1.21]; RR per SD decrease in natural log-transformed DC, 1.14[1.05-1.23]; RR per SD decrease in natural log-transformed YEM, 1.13[1.04-1.22]) and deep CMBs (RR, 1.17[1.00-1.36]; 1.24[1.07-1.43]; 1.22[1.06-1.41] respectively) but not with lobar CMBs. When further adjusted for baseline vascular risk factors including blood pressure and use of blood pressure lowering drugs, the presence of carotid plaque, prevalent CMBs, subcortical infarcts and white matter hyperintensities, the associations persisted. Conclusion: Our findings support the hypothesis that localized increases in carotid arterial stiffness may contribute to the development of CMBs, especially those occuring in a deep location.

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Factors Associated with Inadequate Birth Intervals in the BRISA Birth Cohort, Brazil

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics ◽

10.1055/s-0040-1701463 ◽

2020 ◽

Vol 42 (02) ◽

pp. 067-073

Author(s):

Raphael Barbosa ◽

Maria Teresa Seabra Soares Britto Alves ◽

Ian Nathasje ◽

Deysianne Chagas ◽

Vanda Ferreira Simões ◽

...

Keyword(s):

Gestational Diabetes ◽

Birth Interval ◽

Multinomial Logistic Regression ◽

Short Interval ◽

Univariate Analysis ◽

P Value ◽

Birth Intervals ◽

Short Intervals ◽

Factors Associated ◽

Prenatal Visits

Abstract Objective To determine the prevalence of inadequate birth interval and its associated factors in the BRISA study. Methods Cross-sectional study using data from the BRISA cohort. Birth interval was categorized into “adequate” (≥ 2 years or < 5 years between births), “short interval” (< 2 years) and “long interval” (≥ 5 years). The analysis of the factors associated with short and long birth intervals used multinomial logistic regression. Results The prevalence of adequate birth intervals was 48.3%, of long intervals, 34.6%, and of short intervals, 17.1%. Skin color, age, education level, economic status, type of delivery, number of prenatal visits, parity, blood pressure, diabetes, and anemia (p-value was < 0.2 in the univariate analysis) proceeded to the final model. The variable ≥ 3 births (odds ratio [OR] = 1.29; confidence interval [CI]: 1.01–1.65) was associated with short intervals. Age < 20 years old (OR = 0.48; CI: 0.02–0.12) or ≥ 35 years old (OR = 2.43; CI: 1.82–3.25), ≥ 6 prenatal visits (OR = 0.58; CI: 0.47–0.72), ≥ 3 births (OR = 0.59; CI: 0.49–0.73), and gestational diabetes (OR = 0.38; CI: 0.20–0.75) were associated with long intervals. Conclusion Older mothers were more likely to have long birth intervals, and higher parity increases the chances of short birth intervals. Furthermore, gestational diabetes and adequate prenatal care presented higher chances of having adequate birth intervals, indicating that health assistance during pregnancy is important to encourage an adequate interval between gestations.

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Platelet to Lymphocyte Percentage Ratio as a Marker of Arterial Stiffness in Hemodialysis Patients‎

Journal of Advances in Medicine and Medical Research ◽

10.9734/jammr/2021/v33i1130930 ◽

2021 ◽

pp. 102-112

Author(s):

Hend H. Al Gazzar ◽

Amr M. El-Badry ◽

Tamer A. El-Bedewy ◽

Gamal F. El-Naggar

Keyword(s):

Arterial Stiffness ◽

Low Density Lipoprotein ◽

Ankle Brachial Index ◽

Density Lipoprotein ◽

Hemodialysis Patients ◽

P Value ◽

University Hospitals ◽

Cross Sectional ◽

Complete Blood Counts ◽

Percentage Ratio

Aim of the Work: To evaluate platelet to lymphocyte percentage ratio as a marker of arterial stiffness in hemodialysis Study Design: Cross sectional. Place and Duration of Study: Tanta University Hospitals; Hemodialysis Units, from June 2019 till October 2020. Methodology: The study included 80 end stage renal disease patients (40 males and 40 females) on regular hemodialysis for at least 3months. Laboratory investigations included complete blood counts (CBC), lipid profile, serum albumin, calcium, phosphorus, parathormone hormone, uric acid and C-reactive protein (CRP). Ankle brachial index (ABI) was measured using a hand held Doppler. Data obtained was statistically analyzed. Results: In our study, abnormal ankle-brachial index was found to be associated with high neutrophil %, high platelet count, high platelet lymphocyte percentage ratio (PL%R) and platelet lymphocyte ratio (PLR), elevated cholesterol and low density lipoprotein levels, and presence of cerebrovascular and coronary artery diseases. In multivariate analysis, PL%R and PLR were independently related to abnormal ABI in hemodialysis patients with P value 0.03 and 0.04 respectively. PL%R had sensitivity 92% and specificity 83% while PLR had sensitivity 81% and specificity 60%. There was a positive correlation between PL%R and CRP as a marker of inflammation. Conclusion: Increased platelet-to-lymphocyte percentage ratio was independently associated with increased arterial stiffness in hemodialysis patients.

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HUBUNGAN LAMA WAKTU MENDERITA STROKE DENGAN TINGKAT KEMANDIRIAN KLIEN DALAM MELAKUKAN AKTIVITAS PEMENUHAN KEBUTUHAN SEHARI-HARI

Jurnal Kesehatan Saelmakers PERDANA ◽

10.32524/jksp.v1i2.382 ◽

2018 ◽

Vol 1 (2) ◽

pp. 58

Author(s):

Setia Budi ◽

Ria Dila Syahfitri

Keyword(s):

Data Analysis ◽

Univariate Analysis ◽

Sampling Technique ◽

P Value ◽

Cross Sectional ◽

Stroke Incidence ◽

Bivariate Data ◽

Cross Sectional Design ◽

Interviewing Techniques ◽

Need For Rehabilitation

The rate of stroke incidence is about 200 per 100,000 people throughout the world. This study aims to determine the Relation Suffer Stroke With Independence Level In Neurology Polyclinic TK II DR Ak Gani Palembang Year Hospital 2017. The research method used is descriptive quantitative with cross sectional design that is done by interviewing techniques with questionnaires on 42 respondents with Accidental sampling technique. This research was conducted in August 2017. Data analysis used is univariate data analysis and bivariate data analysis with one way anova test result. The results of univariate analysis showed that the duration of the respondents suffering from stroke was between 2.10 years to 3.38 years. Also found that most respondents were at the level of independence f; independent, except bathing, dressing, moving, and one other function with a total of 12 respondents. The results showed that there was a significant relationship between the long suffering stroke with the level of independence with the value of p value 0.025. For that the need for rehabilitation to patients and families of patients in order to help improve the independence of stroke patients in doing their daily activities. Keywords : Long Suffer Stroke, Level of Independence

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NILAI ANKLE BRACHIAL INDEX PADA PENDERITA DIABETES MELITUS TIPE 2 SESUDAH MELAKUKAN BUERGER ALLEN EXERCISE DI PUSKESMAS WILAYAH KECAMATAN NGANJUK

Jurnal Penelitian Keperawatan ◽

10.32660/jurnal.v4i1.318 ◽

2018 ◽

Vol 4 (1) ◽

Author(s):

Supriyadi . ◽

Nurul Makiyah ◽

Novita Kurnia Sari

Keyword(s):

Ankle Brachial Index ◽

Control Group ◽

P Value ◽

Test Design ◽

Purposive Sampling ◽

Paired Samples ◽

Post Test ◽

Diabetes Melitus

Buerger Allen Exercise mampu meningkatkan pemakaian glukosa oleh otot yang aktif sehingga glukosa dalam darah dapat menurun, dapat membantu mencegah terjadinya penyakit arteri perifer, serta meningkatkan aliran darah ke arteri dan berefek positif pada metabolisme glukosa. Penelitian ini bertujuan untuk mengetahui nilai ankle brachial indexpada penderita diabetes melitus tipe 2setelah melakukan Buerger Allen exercise. Jenis penelitian ini adalah quasy-experiment dengan pre-post test design with control group. Jumlah sampel 60 penderita diabetes melitus tipe 2 dengan purposive sampling, dibagi menjadi 2 kelompok yaitu kelompok perlakuan dan kelompok kontrol. Responden kelompok perlakuan diberikan intervensi Buerger Allen exercise sebanyak 12 kali selama 15 hari.Penelitian dilakukan di wilayah Puskesmas Kecamatan Nganjuk.Data hasilpengukuran nilai ankle brachial indexberupa ratio dan diuji statistik dengan Paired Samples Test. Didapatkan p value 0.001 untuk kelompok perlakuan (p value< 0.05) yang menunjukkan bahwa adanya perubahan bermakna secara statistik nilai ankle brachial index sesudah melakukan Buerger Allen exercise. Dapat disimpulkan bahwa nilai ankle brachial indexpada penderita diabetes melitus tipe 2 meningkat sesudah melakukan Buerger Allen exercise. Kata kunci :penderita diabetes melitus tipe2, Buerger Allen Exercise, Ankle brachial index

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HUBUNGAN ANTARA USIA DAN PENDIDIKAN IBU DENGAN PEMERIKSAAN KEHAMILAN DI KLINIK BUDI MULIA PALEMBANG TAHUN 2014

Jurnal Kebidanan : Jurnal Medical Science Ilmu Kesehatan Akademi Kebidanan Budi Mulia Palembang ◽

10.35325/kebidanan.v5i1.74 ◽

2019 ◽

Vol 5 (1) ◽

Author(s):

Rubiyati Rubiyati

Keyword(s):

Prenatal Care ◽

Antenatal Care ◽

Gestational Age ◽

Significant Relationship ◽

Univariate Analysis ◽

Survey Method ◽

Bivariate Analysis ◽

P Value ◽

Chi Square ◽

Cross Sectional

ABSTRACT Antenatal Care is the care given to pregnant woman to monitor, support maternal health and maternal detect, whether normal or troubled pregnant women. Aki in Indonesia amounted to 359 in 100.000 live births. The purpose of the study was to determine the relationship between age and education in the clinic Budi Mulia Medika 2014. This study used a survey method whit cross sectional analytic. This is the overall study population of women with gestational age ≥36 weeks who come to visit the clinic Budi Mulia Medika Palembang on February 10 to 18. The study sample was taken in non-random with the technique of “accidental smapling “ with respondents who happens to be there or variable. The obtained using univariate and bivariate analysis using Chi-Square test statistic. The results of the univariate analysis showed that 83,3% of respondents did according to the standard prenatal care, high risk age 40,0 %, 60,0% lower risk of age, higher education 70,0%, 30,0% low education. Bivariate analysis showed that there was no significant relationship betwee age and pregnancy tests wit p value= 0,622, and significant relationship between education and prenatal care with p value= 0,019. From the results of this study are expected to need to increase outreach activities to the community about the importance of examination of pregnancy according to gestational age in an effort to reduse maternal mortality. ABSTRAK Antenatal Care merupakan pelayanan yang di berikan pada ibu hamil untuk memonitor, mendukung kesehatan ibu dan mendeteksi ibu, apakah ibu hamil normal atau bermasalah. Di Indonesia AKI berjumlah 359 per 100.000 kelahiran hidup. Tujuan penelitian adalah untuk mengetahui hubungan antara usia dan pendidikan dengan pemeriksaan kehamilan di klinik budi mulia medika tahun 2014. Penelitian ini menggunakan metode survey analitik dengan pendekatan cross sectional. Populasi penelitian ini adalahseluruh ibu dengan usia kehamilan ≥ 36 minggu yang dating berkunjung ke Klinik Budi Mulia Medika pada tanggal 10-18 Februari. Sampel penelitian ini di ambil secara non random dengan tekhnik ‘’ Accidental Sampling’’ dengan responden yang kebetulan ada atau tersedia. Data yang di peroleh menggunakan analisis univariat dan bivariat menggunakan uji statistik Chi-Square. Hasil analisis univariat ini menunjukan bahwa 83,8% responden melakukan pemeriksaan kehamilan sesuai standar, 16,7% tidak melakukan pemeriksaan kehamilan sesuai standar, usia resiko tinggi 40,0%, usia resiko rendah 60,0%, pendidikan tinggi 70,0 %, pendidikan rendah 30,0 %. Analisis bivariat menunjukan bahwa tidak ada hubungan bermakna antara usia dengan pemeriksaan kehamilan dengan p value =0,622, ada hubunngan bermakana antara pendidikan dengan pemeriksaan kehamilan dengan p value = 0,019. Dari hasil penelitian ini di harapkan perlu meningkatkan kegiatan penyuluhan kepada masyarakat tentang pentingnya dilakukan pemeriksaan kehamilan sesuai dengan umur kehamilan sebagai upaya menurunkan angka kematian ibu.

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