scholarly journals INFLUENCE OF TECHNOLOGICAL PARAMETERS OF THE ULTRAFILTRATION PROCESS OF CITRUS JUICES ON THEIR QUALITY

2019 ◽  
Vol 7 ◽  
pp. 884-890
Author(s):  
Irina Bejanidze ◽  
Tina Kharebava ◽  
Nunu Nakashidze ◽  
Lamzira Komcelidze ◽  
Nazi Davitadze
Keyword(s):  
Human Body ◽  
Hollow Fibers ◽  
Toxic Substances ◽  
Technological Parameters ◽  
Static Mode ◽  
Good Opportunity ◽  
Treatment And Prevention ◽  
Citrus Juices ◽  
Calcium Iron ◽  
Ultrafiltration Process

Fresh fruit juices contain organic acids and mineral substances (potassium, calcium, iron, copper, magnesium, phosphorus, manganese, molybdenum, boron, iodine), and their salts, large amounts of fiber, pectin and enzymes - complex substances, that contribute to the food processing and absorption of nutritional elements. Natural citrus juices contain essential vitamins and nutrients for the human body. Therefore, they represent a good opportunity for the treatment and prevention of various diseases. With the vitamins, taken through the juice, the human body becomes more resistant to viruses and infections, stressful situations and intense physical stress, and the body’s metabolism becomes normalized. Beverages, prepared from juices improve intestinal motility and thus contribute to improving the allocation of toxic substances and slags from the organism. The purpose of this work is the development of technological parameters of the ultrafiltration process to obtain natural juices which are sterile, resistant to precipitation and turbidity, and have a long shelf life. This paper examines the performance of the ultrafiltration process of citrus juices (lemon, tangerine, orange) and its dependence on the pressure and duration of the process, type and porosity of the membrane, the nature of the juice, and acidity. The juice composition was studied before and after ultrafiltration. It was established, that the productivity of the ultrafiltration process depends on: the duration of the process and this dependence is determined by the nature of the process: membrane type, in particular, filtration material and pressure: with an increase in membrane porosity and pressure, the productivity of the process, the volume of filtered juice, filtering speed and duration increases; the productivity of the ultrafiltration process, during the filtration both in dynamic and static mode, depends on the type and consistency of the juice: it increases with the increase of juice acidity. It was established: the general acidity (1.17%), density (1.038 g/cm3), the content of dry substances (9.9%), sugars (7.8%), including invert (7.2%), ash ( 0.26%), and vitamin C ( 20mg/ 100gr.), do not change in the course of ultrafiltration of tangerine juice. The viscosity, the content of carotenoids, cellulose and pectin decreases. The amino-acid structure practically does not change; hollow fibers detain only 6 - 8% of proteins and amino acids. For obtaining high-quality citrus juices, ultrafiltration should be carried out at a pressure 0.2MPa, on hollow fiber, in a dynamic, circulating mode. The juices obtained by ultrafiltration on hollow fibers (AP-2.0) are sterile, resistant to precipitation and turbidity, have significantly increased shelf lives, and they retain their organoleptic properties and nutritional values.

scholarly journals Justification of sorption composite usage on the basis of nanodisperse silica for sepsis prevention in complex treatment of purulent-inflammatory processes

2019 ◽  
Vol 41 part 3 (2) ◽  
pp. 45-50
Author(s):  
O. A. Viltsaniuk ◽  
P. V. Belyaev ◽  
T. P. Osolodchenko ◽  
O. O. Viltsaniuk
Keyword(s):  
Antimicrobial Activity ◽  
Antimicrobial Properties ◽  
Statistical Processing ◽  
Toxic Substances ◽  
Adhesive Properties ◽  
Adhesion Properties ◽  
E Coli ◽  
Adhesion Ability ◽  
Treatment And Prevention ◽  
Inflammatory Processes

Introduction. The problem of purulent-inflammatory processes treatment and the prevention of sepsis remains one of the most pressing problems of surgery.Purpose of the study. Is to estimate the effectiveness of sorption composition with antimicrobial properties on the basis of nanodisperse silica on the adhesive properties of microorganisms and to substantiate the expediency of its use for the purulent and inflammatory processes treatment and prevention of sepsis.Materials and methods.To determine the antimicrobial activity and the influence of the antiseptics of decasan, myramistin, ethonium, chlorhexidine and the sorption on the microorganisms adhesion properties composition was used the method of diffusion in agar of the museum strains of microorganisms S. Aureus ATCC 25923, E. Coli ATCC 25922, R. Vulgaris 4636, R. Aureginosa ATCC 27853, S. AIbicans 855/653, SI. Perfringens 28, Peptostreptococcus anaerobicus 22, Bacteroides fragilis 13/83, and clinical strains of S. Aureus, R. Aeuroginosa, E. Coli. Adhesive properties of microorganisms were studied according to the Brillis method et al. (1986) with the subsequent statistical processing of the data.Results. Studies have shown that antiseptics have high antimicrobial activity and reduce the adhesion ability of microorganisms. But the use of only antiseptics or only antibiotics for the purification of purulent foci can lead to toxins absorption and tissue decay products from purulent foci. That processes could be the trigger mechanism for sepsis development. The sorption composition is able to reduce the adhesive activity of bacteria, allows to absorb toxic substances from pathological foci, what preventing their resorption and thereby prevent the development of sepsis.Conclusions. The composition made from sorbents and antiseptics is not inferior to antimicrobial activity to antiseptics, which can reduce the virulence of bacteria, by reducing their adhesive activity, and absorb toxins of microorganisms and tissue decomposition products on their surface, thus prevent their absorption, which will prevent the purulent-inflammatory process progression and sepsis development.Keywords: sorption composition, nanodisperse silica, antiseptics, adhesive properties of microorganisms, prevention of sepsis.

scholarly journals Drinking water. Microscopic fungi. Mycotoxins (literature review)

2019 ◽  
pp. 253-259
Author(s):  
Dmytro Zabolotnyi ◽  
Adel Rudenko ◽  
Mariia Saprykina
Keyword(s):  
Drinking Water ◽  
Literature Review ◽  
Human Body ◽  
Tap Water ◽  
Toxic Substances ◽  
Microscopic Fungi ◽  
Medical Sciences ◽  
Yeast Fungi ◽  
The Subject ◽  
And Oxidative Stress

We have analized available literature on the capability of micro- scopic fungi (micromycetes) to exist and reproduce in the water (i.e. tap water) that is provided to consumers. The following mi- cromycetes, most typically present in tap water, were identified, namely: Aspergillus, Fusarium, Penicillium, Alternaria, Clad- osporium and Candida. The average number of micromycetes ranges from 8 to 18 CFU/100 cm3 , with yeast fungi dominantly present. Toxic substances (mycotoxins) that produce microscop- ic fungi are described, as well as their effects on the human body. It is noted that most mycotoxins stimulate formation of excessive free radicals and oxidative stress, which leads to impaired func- tion of the body’s antioxidant system, namely the production of a prooxidant enzyme in liver cells, immune organs and in the gastrointestinal tract. Therefore, , the presence of processes of apoptosis that lead to little sorption syndrome, immunosuppres- sion. The potential water routes of mycotoxins into the human body have been identified. The ability of mycotoxins, which form micromycetes – most often found in tap water, to cause cancer, have been analyzed in detail, using available literature on the subject. Mainly the effect of aflatoxins, trichothecenes, ochratox- ins and gliotoxins was examined. The presence of microscopic fungi in water supplied to the consumer, as well as their ability to form toxins necessitates systematic studies of water samples for the detection of micromycetes and the toxins present in it. And, finally, an important avenue for further research is outlined, which is to develop a simple and affordable method for the de- tection of mycotoxins in the water, based on the use of a sensitive test objects. Key words: drinking water‚ micromycetes‚ mycotoxins‚ human health For citation: Zabolotnyi DI, Rudenko AV, Honcharuk VV, Saprykina MM, Bolgova OS. Drinking water. Microscopic fungi. Mycotoxins (literature review). Journal of the National Academy of Medical Sciences of Ukraine. 2019;25(3):253–59

scholarly journals Research of acute toxicity, allergizing and local-irritative action of the veterinary drug “Yodozol”

2019 ◽  
pp. 54-58
Author(s):  
R. M. Sachuk ◽  
S. V. Zhyhalyuk ◽  
I. M. Lukyanik ◽  
M. S. Mandyhra ◽  
Ya. S. Stravsky ◽  
...  
Keyword(s):  
Body Weight ◽  
Acute Toxicity ◽  
Behavioral Responses ◽  
Physiological Parameters ◽  
Laboratory Animals ◽  
Veterinary Drug ◽  
Intragastric Administration ◽  
Toxic Substances ◽  
Treatment And Prevention ◽  
Mucous Membranes

The purpose of the work was to determine, in experiments on rodents, the parameters of acute toxicity, allergenic and locally irritative effects of iodine-containing uterine drug for the treatment and prevention of intrauterine infections of animals. Materials and methods. Preclinical studies of acute toxicity of “Yodosol” containing iodine and potassium iodide were performed on 90 white mice, 30 white outbred rats and 6 rabbits. Clinical, pharmacotoxicological and statistical methods were used. Results of work. It has been found that at intragastric administration in experimental rats and mice, DL50 values exceed 8,000 mg/kg body weight and have no effect on the behavioral responses and physiological parameters of laboratory animals. It has been investigated that “Yodosol” aerosol has no local toxic and irritant effects on the skin and mucous membranes of laboratory animals (rabbits). Conclusions. The use of the drug «Yodosol», in doses above 8,000 mg/kg body weight, does not affect the behavioral responses and physiological parameters of laboratory animals. The drug has no local toxic and irritant effects on the skin and mucous membranes. According to the requirements of SOU 85.2-37-736:2011 and GOST 12.1.007-76, the newly developed drug “Yodosol” belongs to low-toxic substances — 4 toxicity classes

scholarly journals ASSESSMENT OF CADMIUM CONTENT IN COSMETICS BY EXTRACTION WITH DILUTED HCl AND AQUA REGIA

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Dijana Mihajlović ◽  
Vesna Antunović ◽  
Tanja Okolić ◽  
Dijana Jelić
Keyword(s):  
Heavy Metals ◽  
Human Body ◽  
Technological Development ◽  
Atomic Absorption Spectrophotometry ◽  
Toxic Substances ◽  
Cadmium Content ◽  
Cosmetic Products ◽  
Aqua Regia ◽  
Official Gazette ◽  
The Republic

The intensive industrial and technological development results in an appearance of a large amount of pollutants and toxic substances in the biosphere including large quantities of heavy metals. Some heavy metals are biogenic (Cu, Zn, Se etc.) and essential for proper maintaining of the metabolism in the human body. The main dangers to the human health are associated with the exposure to toxic elements such as Pb, Cd, Hg and As. Emission of Cd in the environment has increased during the 20th century mainly due to the recycling of the products containing this element. Cadmium accumulates in the human body with a biological half-life from 10 to 30 years and could cause very serious toxic effects. Cosmetic products are potentially a source of cadmium as well as some other heavy metals mostly due to the frequent and uncontrolled usage of cosmetics of poor аnd/or suspicious quality. The goal of the study is to determine the cadmium content in various cosmetic products (lipsticks, eyeshadows and blushes) present in the markets of the Republic of Srpska. The content of Cd was determined with atomic absorption spectrophotometry (AAS) after the extraction with diluted HCl and aqua regia. The results of the research show that the cadmium concentrations in the investigated products are in accordance with the regulations of the Republic of Srpska (Regulations on safety of consumer goods; „Official Gazette RS“ – No.17/15).

The effect of diethylene glycol on pollution from offshore gas platforms

2018 ◽  
Vol 15 (2) ◽  
pp. 74
Author(s):  
Michela Mannozzi ◽  
Giorgio Famiglini ◽  
Achille Cappiello ◽  
Chiara Maggi ◽  
Pierangela Palma ◽  
...  
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Solvent Effect ◽  
Aromatic Hydrocarbons ◽  
Diethylene Glycol ◽  
Artificial Seawater ◽  
Dynamic Mode ◽  
Offshore Platforms ◽  
Toxic Substances ◽  
Static Mode ◽  
Polycyclic Aromatic

Environmental contextMarine mining activities are potential sources of environmental pollution. Diethylene glycol used in offshore platforms has been suspected to facilitate the release of toxic substances into the sea. The results obtained elucidate that this release is not significant for the metals examined here, apart from iron, nor for polycyclic aromatic hydrocarbons, even at very high diethylene glycol concentrations. AbstractThe role of diethylene glycol (DEG) as a co-solvent for selected organic and inorganic pollutants adsorbed onto the particulate matter in produced formation water (PFW) from offshore gas platforms is thoroughly evaluated. Artificial seawater samples were spiked with certified sediments containing several polycyclic aromatic hydrocarbons (PAH) and metals. Aliquots (1 L) containing no DEG and DEG at 3500 and 5000 mg L−1 were kept in static and dynamic modes for 24 h before analysis to allow sufficient partitioning time between solid and liquid phases for the selected analytes. The Italian legislation on this matter sets 3500 mg L−1 as the highest concentration for DEG in PFW. In our experiments, concentrations equal to and above the set limit were chosen to enhance any possible co-solvent effect. Real PFW samples were also analysed, both with and without DEG. The analyses were conducted by using GC-MS for the PAH, and ICP-MS for the metals. A minor co-solvent effect was observed for low-molecular-weight PAH in the artificial seawater in static mode. Among metals, only iron showed an increase in solubility in the presence of DEG, demonstrating the co-solvent effect of DEG. The experiments in dynamic mode revealed no increase in the solubility of any other analytes in the liquid phase compared with static mode.

scholarly journals How Combining Grounding and Acupuncture Simultaneously Increases Beneficial Outcomes Over Traditional Acupuncture?

2021 ◽  
Vol 3 (5) ◽  
pp. 20-24
Author(s):  
Madiha Khalid ◽  
Jeremy Madvin
Keyword(s):  
Side Effects ◽  
Human Body ◽  
Clinical Importance ◽  
Therapeutic Effectiveness ◽  
Wound Treatment ◽  
Chemical Substances ◽  
Immunological Responses ◽  
Treatment And Prevention ◽  
The Earth ◽  
Multidisciplinary Studies

Multidisciplinary studies showed that when the human body is electrically in contact with the Earth (earthing or grounding), it produces intriguing consequences on the physiology and health of the human being. These effects are related to treating acute and chronic inflammatory and autoimmune illnesses, immunological responses, wound treatment, and prevention. At the same time, acupuncture in Traditional Medicine has been widely utilized for its low side effects and therapeutic effectiveness as primary therapeutic therapy. However, the electrical reaction to acupuncture stimulation has not been investigated in conditions with acupuncture that could alter acupuncture therapeutic effectiveness. The study's objective is to inform scientists of the apparent innovative approach to inflammation studies; and alert researchers to the importance of the duration and the degree of grounding, which may affect the results of inflammation, injury, and tumorigenesis studies. Grounding with acupuncture decreases pain and changes the quantity of circulating neutrophils and lymphocytes and circulating chemical substances linked to inflammation. This work reviews the potential of acupuncture with earthing as an easy and readily accessible worldwide modality of substantial clinical importance is reviewed in this work.

scholarly journals CARBON (II) MONOXIDE AS A SUBJECT FOR POISONS STUDYING OF STUDY ON DISCIPLINE TOXICOLOGICAL CHEMISTRY (CRIMINAL ANALYSIS) AT THE PHARMACEUTICAL DEPARTMENT OF THE NATIONAL MEDICAL UNIVERSITY IN UKRAINE

2016 ◽  
Vol 4 ◽  
pp. 744-749
Author(s):  
Yaroslav Tsekhmister ◽  
Elena Welchinska
Keyword(s):  
Human Body ◽  
Toxic Substances ◽  
Analytical Toxicology ◽  
Chemical Substances ◽  
National Medical ◽  
Medical University

Toxicological Chemistry (or Analytical Toxicology) is a field among other pharmaceutical disciplines that investigates the characteristics of toxic substances and poisons, their actions in the human body and in the cadaver material, and the ways of segregating, qualitatively detecting, and quantitatively defining poisons and their metabolites. The aim of this article is to explain the importance of studying common chemical substances, such as carbon (II) monoxide (or charcoal gas), which is a strong poison, in this chemistry field, i.e., Toxicological Chemistry, throughout the whole educational period at the Faculty of Pharmacy of the National Medical University in Ukraine.

scholarly journals ON THE POSSIBILITY OF THE RAPID ASSISTANCE TO PEOPLE AFTER A SINGLE EXPOSURE TO URANIUM HEXAFLUORIDE

2018 ◽  
Vol 97 (3) ◽  
pp. 213-219 ◽  
Author(s):  
S. P. Babenko ◽  
Andrey V. Badyin ◽  
A. V. Ovchinnikov
Keyword(s):  
Human Body ◽  
Aerosol Particles ◽  
Toxic Substance ◽  
Theoretical Method ◽  
Uranium Hexafluoride ◽  
The Body ◽  
Toxic Substances ◽  
Functional Changes ◽  
Working Space ◽  
Hydrolysis Products

Introduction. The accidental release of uranium hexafluoride (UHF) is associated with the pollution of the air of the working premises with its hydrolysis products, containing toxic substances (uranium and fluorine). The intake of UHF hydrolysis products by is related to a negative impact on the human body. The magnitude and the rate of the exposure are determined by the amount of deposited toxic substances. Known methods for the determination of these amounts are based on the study of involved biological media (urine, blood, postmortem examination of all organs), requiring time-consuming, sometimes are critical for the preservation of the human life. In this paper, we propose a theoretical method for the detecting the amount of the deposited toxic substances. The calculation is based on models constructed by authors of this article. They describe successively: pollution of the working premises with UHF hydrolysis products, the input of toxic substances in the human body, uranium and passing fluorine through the body. The first model includes the following processes: hydrolysis, the formation of aerosol particles as on the deposition gas molecules and the wall of working space as on the human skin, deposition of the aerosol particles on the floor of the working space. With continuity equations written for the concentrations of molecules of substances of interest to us, the analytical expressions for n(z,t) - the concentration of atoms of a toxic substance at the height z at the time t; j(t) - flux density of toxic substance atoms on the surface of the skin at the time t. The second and third models describe percutaneous intake and inhalation of uranium and fluorine consisting of UHF hydrolysis products entering the human body, as well as toxic substances passed through the body. Results. There are presented results of calculating the amounts deposited in the body of uranium fluoride at various time points. There is given a comparison of these values with the experimental data in the literature on the quantity of uranium and fluorine, which enters the body to cause various organic and functional changes. Conclusion. The theoretical method of determining a person’s level of the destruction was concluded to allow extending the prediction of the development of adverse effects of uranium and fluorine without its prior survey, and choose the most effective methods of healthcare provision.

scholarly journals Hypothetical model of COVID-19: origin,spread,binding,infection,treatment and prevention(Version10）

2020 ◽  
Author(s):  
Alex Lee
Keyword(s):  
High Temperature ◽  
Body Temperature ◽  
Human Body ◽  
Human Infection ◽  
The Body ◽  
Human Immune System ◽  
Treatment And Prevention ◽  
Hypothesis Model ◽  
The World ◽  
Prevention Method

2019 Coronavirus Hypothesis Model, preliminary hypothesis model, no experiments have been conducted yet. For laboratory reference only, please do not apply this theory before experimental verification. This article discusses the origin of the 2019 Coronavirus, the principles of human infection, the principles of transmission, high binding, changes in human temperature, prevention and treatmen.2019 Coronavirus originates from bats or other animals. In bats, this virus is a cooling factor. Due to the high temperature of bats, this cooling factor lowers the temperature of bats and belongs to normal life activity, it will not produce immune activation, and thus will not produce infections and diseases in the bat body. When this cooling factor enters the human body, especially when the temperature is low, the virus starts the function of the cooling factor in the human body, that is, to lower the human body temperature, the chill happens. The human immune system starts the immune function and gives a fever to fight the cooling. The replication and binding of the 2019 Coronavirus depends on the temperature of the surrounding cells. The higher the temperature, the more replicated and the stronger the binding. Therefore, the fever of the human body promotes the aggravation of the disease. addition to those suspected of having a fever, people whose body temperature is lower than normal may also be infected with 2019 Coronavirus. The way for bats to inhibit the replication of 2019 Coronavirus is high temperature, to avoid body temperature too low. It can be experimented to put the human body in a higher temperature environment, the heat is transmitted to the body, and the low temperature factor of the 2019 Coronavirus can be overcome. The hypothetical prevention method is: everyone in the world isolates for a certain period of time, and raises the temperature around the human body, so that everyone in the world has no 2019 Coronavirus.

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