scholarly journals The correlation of obesity, smoking, fried foods consumption pattern and food intake with lipid profile in civil servant in Yogyakarta, Indonesia

Author(s):  
Toto Sudargo ◽  
Fahmi Tiara Sari ◽  
Novita Dian Naomi

Background: Dyslipidemia is an abnormal change in the levels of lipid profile such as increased levels of total cholesterol, LDL, triglycerides or decreased levels of HDL. The proportion of the Indonesian population (> 15 years old) with a total cholesterol level above the normal value amounted to 35,9%.  Objective: To determine the correlation of obesity, smoking, fried food consumption pattern and food intake with lipid profile in civil servant in Yogyakarta.Methods: This study is an observational study with cross sectional design at employees of Gadjah Mada University who perform medical check-up at the GMC-Health Center Yogyakarta. There are 179 respondents in the study.  Subjects are categorized to have dyslipidemia (based on NCEP ATP III criteria) if it meets ≥ 1 of the following criteria: (1) Total cholesterol ≥ 200 mg/dL; (2) LDL cholesterol ≥ 130 mg / dL; (3) HDL cholesterol < 40 mg / dL; and (4) Triglycerides ≥150 mg / dL. Fried food consumption patterns and food intake is obtained using semi-quantitative food frequency questionnaire (SQ-FFQ). Data were analyzed by Chi Square, Independent t test and Mann Whitney test (adjusted for scale variables used) with a confidence level of 95%.Results: One hundred and fifty five of 179 respondents (87.3%) diagnosed with dyslipidemia. There are 52% abnormal cholesterol, abnormal LDL 67%, 43% and 28.5% with abnormal HDL and abnormal triglycerides, respectively. The statistical test showed the correlation of obesity (p=0,022), smoking (p=0,013), the type of fried food (p=0.047), the amount of fried foods (p=0,013) and fat intake from fried foods (p=0.036) has significant association with lipid profile levels.Conclusions: There is significant correlation between obesity, smoking, type of fried food, amount of fried foods and fat intake from fried food with lipid profile levels.

2018 ◽  
Vol 12 (2) ◽  
pp. 129
Author(s):  
Hadiar Huriyah Rahma ◽  
R. Bambang Wirjatmadi

Coronary Heart Disease (CHD) is a condition where plaque build up inside the coronary artery which could lead to heart attack. One of the factors that affects CHD is food consumption pattern that can increase lipid level so the heart could not get any nutrition optimally. The research was aimed to analyze the relationship between food consumption pattern, and lipid profi le with CHD in elderly patients of Jemursari Islamic General Hospital, Surabaya. The study was a case control design with 20 of case patients who had CHD history and 20 of control patients with dyslipidemia. The analysis used chi-square test for the variables such as carbohydrates and fat intake, meal frequency, total cholesterol level, Low Density Lipoprotein (LDL), and triglycerides level. The result showed that there is relationship between fat intake and CHD (p=0.002; OR=13.500; 95%CI), but there were no relationship between carbohydrates intake (p= 0.105), meal frequency (p=0.451), total cholesterol level (p = 0.237), Low-Density Lipoprotein (LDL) (p = 0.054), and triglycerides level (p=0.341), with CHD in dyslipidemia elderly patient. Elderly patients is expected to maintain their nutrient intake, especially fat intake in order to reduce the chance of CHD.


2018 ◽  
Vol 69 (2) ◽  
pp. 403-406
Author(s):  
Codrina Ancuta ◽  
Cristina Pomirleanu ◽  
Cristina Iordache ◽  
Magda Ecaterina Antohe ◽  
Rodica Chirieac ◽  
...  

Data about lipoprotein changes and their link with cardiovascular disease and atherosclerosis in systemic sclerosis (SSc) are still challenging. We aimed to evaluate serum lipid profile of patients with SSc and to identify potential relation with different disease specific characteristics (clinical, serological, inflammatory tests) in a cross-sectional study. Standard assessments comprised SSc-related parameters (disease subtype, clinical spectrum, immunological tests) and lipid metabolism (total cholesterol and fractions, triglycerides). Impaired lipid profile (low serum HDL- and high LDL-cholesterol, increased serum triglycerides, slightly modification in total cholesterol level) significantly correlated with diffuse SSc, activity (EUSTAR) and severity (MEDSGER), as well as seropositivity for specific antibodies (anti-centromere and anti-topoisomerase 1). The dyslipidemic profile might represent a pathobiological pathway for atherosclerosis in SSc.


2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Seongil Kang ◽  
Sangyeol Song ◽  
Joosang Lee ◽  
Hyekyung Chang ◽  
Sanghun Lee

Objectives. Several experimental studies have reported antiobesity and lipid-improving effects of Citrus unshiu. However, clinical studies on its effects are lacking. This study was designed to evaluate the impact of Citrus unshiu peel pellet (CUPP) on obesity and lipid profile. Methods. For 118 patients with body mass index (BMI) > 23 who took Citrus unshiu peel pellet (CUPP) for 4 weeks in a Public Health Center, laboratory and biometric readings before and after CUPP administration were analyzed. Results. Mean age of these subjects was 53.8±10.6 years (range: 18-75 years). There were 88 (74.6%) females in the study sample (n = 118). A significant (p < 0.01) decrease in BMI from 27.47±2.24 to 27.27±2.22 was observed in all subjects after CUPP treatment and 65.3% (N = 77) of them lost 1.03±0.83 kg of weight after 4 weeks of treatment. Total cholesterol level was significantly (p < 0.01) decreased from 204.0±37.4 mg/dL to 193.5±36.5 mg/dL. Significant (p < 0.05) decreases in levels of low-density lipoprotein, cholesterol, and triglyceride were also observed. Conclusions. These results suggest that CUPP in practice could help weight control and improve total cholesterol level. Findings of this study provide clinical foundation for future large-scale trials to establish clinical benefits of CUPP.


2014 ◽  
Vol 112 (6) ◽  
pp. 984-991 ◽  
Author(s):  
Carmen Sayon-Orea ◽  
Maira Bes-Rastrollo ◽  
Alfredo Gea ◽  
Itziar Zazpe ◽  
Francisco J. Basterra-Gortari ◽  
...  

Reported associations between the consumption of fried foods and the incidence of obesity or weight gain make it likely that fried food consumption might also be associated with the development of hypertension. However, evidence from long-term prospective studies is scarce. Therefore, the aim of the present study was to longitudinally evaluate this association in a prospective cohort. The SUN (Seguimiento Universidad de Navarra) project is a Mediterranean cohort study of university graduates conducted in Spain, which started in December 1999 and is still ongoing. In the present study, we included 13 679 participants (5059 men and 8620 women), free of hypertension at baseline with a mean age of 36·5 (sd 10·8) years. Total fried food consumption was estimated at baseline. The outcome was the incidence of a medical diagnosis of self-reported hypertension during the follow-up period. To assess the association between the consumption of fried foods and the subsequent risk of developing incident hypertension during the follow-up period, Cox regression models were used. During a median follow-up period of 6·3 years, 1232 incident cases of hypertension were identified. After adjusting for potential confounders, the adjusted hazard ratios for developing hypertension were 1·18 (95 % CI 1·03, 1·36) and 1·21 (95 % CI 1·04, 1·41) for those consuming fried foods 2–4 and >4 times/week, respectively, compared with those consuming fried foods < 2 times/week (P for trend = 0·009). In conclusion, frequent consumption of fried foods at baseline was found to be associated with a higher risk of hypertension during the follow-up period in a Mediterranean cohort of university graduates.


Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Luc Djousse ◽  
Andrew Petrone ◽  
John M Gaziano

Background: While previous studies have reported a positive relation of fried food consumption with type 2 diabetes, hypertension, and obesity, no previous study has examined the relation of total fried food intake with risk of heart failure (HF) in a prospective cohort. Objective: To test the hypothesis that fried food consumption is positively associated with risk of HF in male physicians. Methods: A prospective cohort of 19,968 participants from the Physicians’ Health Study. Frequency of fried food consumption was assessed between 1999 and 2002 using a food frequency questionnaire and HF was ascertained through annual follow-up questionnaires with validation in a subsample. We used Cox regression to estimate multivariable adjusted hazard ratios of HF. Results: During a median follow-up of 10.6 years, 862 cases of HF occurred. The mean age at baseline was 66.4 ± 9.2 years. Median frequency of fried food consumption was <1 time per week. Multivariable adjusted hazard ratios (95% CI) were: 1.0 (ref), 1.18 (1.01-1.37), 1.25 (1.02-1.54), and 1.68 (1.19-2.36) for fried food consumption of <1/week, 1-3/week, 4-6/week, and 7+/week, respectively (p for linear trend: 0.0004), after adjustment for age, alcohol use, smoking, exercise, and history of myocardial infarction, coronary artery bypass graph or angioplasty (Fig). Additional adjustment of total trans fats did not alter the findings. In a secondary analysis, body mass index did not modify the relation of fried foods with HF risk. Conclusions: Our data show a positive association between fried food intake and risk of HF in US male physicians.


2014 ◽  
Vol 3 (1) ◽  
pp. 7-12 ◽  
Author(s):  
Indrawati Wurdianing ◽  
SA Nugraheni ◽  
Zen Rahfiludin

Background: Lipid profile effects is a risk factor for Coronary Heart Disease. Soursop leaves (Annona muricata L) isa traditional medicine plant containing metabolic compounds that contribute to the improvement of the lipid profile.Objective: To determine the effects of soursop leaves extract on lipid profile (total cholesterol, LDL cholesterol, HDLcholesterol and triglyceride).Methods: An experimental study using randomized pre-posttest with control group design. Sample consisted of 28 maleWistar rats, were divided into four groups. The control group (K) was only given High Fat High Cholesterol (HFHC)diet and treatment groups (P1, P2, P3) were given a HFHC diet plus Annona muricata L extract with doses of 100, 200and 300 mg/kgBB per day for 28 days respectively. Data were analyzed by Wilcoxon test, Kruskal-Wallis and MannWhitney.Results: The mean total cholesterol level significantly decreased in the treatment group P1 (p = 0.028) from 60.7 mg/dl(47.6-75.3) to 45.5 mg/dl (38.4-62.4). Mean HDL cholesterol level significantly increased in the treatment group P2(p=0.043) from 26.0 mg/dl (19.7-35.3) to 27.9 mg/dl (18.8-38.0). The mean levels of LDL cholesterol and triglyceridedecreased but not significantly.Conclusion: The administration of Annona muricata L extract can decrease total cholesterol and increase HDLcholesterol significantly.


2018 ◽  
Vol 1 (1) ◽  
pp. 230-236
Author(s):  
Hendra Gunawan ◽  
Panal Sitorus ◽  
Rosidah Rosidah

Latar Belakang: Dislipidemia adalah terjadinya kelainan metabolisme lipid, baik peningkatan maupun penurunan fraksi lipid dalam darah. Kelainan fraksi lipid yang utama adalah kenaikan kadar kolesterol total, kenaikan kadar LDL, kenaikan kadar trigliserida serta penurunan kadar HDL. Tingginya kadar lipid dalam darah dapat menyebabkan terjadinya aterosklerosis, yang ditandai dengan terdapatnya ateroma pada bagian intima arteri yang berisi kolesterol, zat lipoid, dan lipofag. Perkembangan lebih lanjut dari aterosklerosis ini akan menimbulkan komplikasi pada organ target diantaranya jantung dan otak. Tujuan Penelitian: Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanol herba poguntano (EEHP) terhadap profil lipid tikus putih jantan dislipidemia (penurunan kadar kolesterol total, kadar trigliserida, kadar LDL dan peningkatan kadar HDL) serta terhadap proses aterosklerosis. Metode Penelitian: Penelitian ini dilakukan terhadap 30 ekor tikus putih jantan yang dibagi dalam 6 kelompok. Kelompok I sebagai kontrol normal, kelompok II sebagai kontrol negatif diberikan Na-CMC dosis 10 ml/kg bb, kelompok III sebagai kontrol positif diberikan atorvastatin dosis 2 mg/kg bb, kelompok IV, V, dan VI sebagai kelompok perlakuan diberi EEHP dosis 75, 150 dan 300 mg/kg bb. Hewan uji diberi induksi pakan tinggi lemak yang berupa campuran kuning telur puyuh, minyak jelantah, dan lemak sapi selama 14 hari berturut-turut untuk mendapatkan hewan uji dislipidemia yang dilanjutkan dengan treatment selama 14 hari berturut-turut. Pengukuran kadar profil lipid dilakukan pada hari ke-28. Hasil: Hasil analisis statistik menunjukkan bahwa EEHP dapat menurunkan kadar kolesterol total, kadar trigliserida, dan kadar LDL serta dapat meningkatkan kadar HDL secara nyata (p < 0,05). Kesimpulan: Berdasarkan hasil diatas, dapat disimpulkan bahwa EEHP mempuyai pengaruh terhadap profil lipid tikus dislipidemia (penurunan kadar kolesterol total, kadar trigliserida, kadar LDL dan peningkatan kadar HDL) serta dapat mencegah proses terjadinya aterosklerosis. Background: Dysplipidemia is a lipid metabolism dysfunctionsuch as the incline and the decline of blood lipid profile. The main abnormallipid fractionlevel are the increase of total cholesterol level, LDL level, and triglyceride and the decline of HDL level. The high level of blood lipid can cause atherosclerosis with the atheroma in arterial intima that contains cholesterol, lipoid, and lipophage. The advance stage of atherosclerosis can cause complications to target organs such as heart and brain. Objectives: This research aimed to evaluate the effects of herbapurganto (PiciaPicriaFelTerraeLour) ethanol extract on Lipid Profile of Dyspilidemic Male Rat(the decline of total cholesterol level, triglyceride level, LDL level, and the increase of HDL level) and also the atherosclerosis process. Research method: This research was conducted to 30male ratswhich dividedinto 6 groups. Group 1was served as the normal control, Group 2was servedas negative controls which were given 10 ml/kg bb Na-CMC , Group 3 was served as positive controls which were given 2 mg/kg bb of atorvastatin dosage, Group 4, 5, and 6 were served as the treatment group, and administered with EEHP at the dose of 75, 150, and 300 mg/kb bb . The test animals were fedwith high fatdiet using quail yolk, used cooking oil, and cow fat mixture for 14 days consecutively to obtain dyslipidemia subjects and continued with 14 consecutively treatment. The measure of lipid profile was conducted in the 28th day. Finding: The statistical analysis results indicated that EEHP could decrease the total of cholesterol level, triglyceride level, LDL level, and also it could increase the HDL level (p < 0.05). Conclusion: Based on the results, it could be concluded that EEHP haseffect towards dyslipidemia rat(the decline of total cholesterol level, triglyceride level, LDL level, and the increase of HDL level) and it could also prevent atherosclerosis.


2007 ◽  
Vol 2 (1) ◽  
pp. 8 ◽  
Author(s):  
Hardinsyah Hardinsyah ◽  
Leily Amalia

<p class="MsoBodyTextIndent3" style="margin: 0cm 12.45pt 6pt 17.85pt; text-indent: 26.95pt;"><span style="font-size: 10pt;" lang="en-us" xml:lang="en-us">The objective of this study was to analyze trend of wheat flour consumption and its processed products in Indonesia since 1993 until 2005.  The data used were food consumption data of Socio-economic Survey (SUSENAS) collected by Statistics Indonesia (Badan Pusat Statistik, BPS). The results showed that the wheat flour consumption and its processed products tended to increase from 1993 to 2005. The rapid increase was occurred in the period of 1993-1996 and 1999-2005.  Three kinds of wheat flour-processed products that significantly increased were instant noodle, fried food and snack for children.  The average consumption level of wheat flour and their processed products in 2005 in urban areas were higher than the consumption level in rural areas, namely 47.7 vs. 36.3 g/cap/d.  Among all of the wheat flour-processed food, wheat flour based-fried food, instant noodle, and noodle with meat ball (mie bakso) were the most three popular kind of wheat flour processed products consumed by Indonesian people, 49.4, 48.6 and 44.7% respectively. The consumption pattern was relatively similar between urban and rural areas.  It indicated that wheat flour processed food had already been a part of food consumption pattern of Indonesian people.</span></p>


2019 ◽  
pp. 13
Author(s):  
Remva Paul ◽  
J.K. Mukkadan

Background: Diabetes is one of the largest global health emergencies of the 21st century. About 425 million people worldwide or 8.8% of adults between the ages of 20-79 years are estimated to have diabetes. There are evidences which show that higher blood glucose and cholesterol levels have an association with free radical-mediated lipid peroxidation. The aim of the study was to compare and correlate glycosylated haemoglobin (HbA1c), lipid peroxidation marker malondialdehyde (MDA), lipid profile, and antioxidant enzyme superoxide dismutase (SOD) activity in subjects with varying levels of glucose metabolism. Materials and methods: This was a cross sectional study. Based on fasting plasma glucose and HbA1c, subjects were divided into diabetic patients (n= 40), pre-diabetic patients (n=38) and normal patients (n=41). Subjects were tested for lipid profile, MDA, and SOD activity. The comparison of parameter between the groups was carried out using one-way ANOVA followed by tukey’s multiple comparison test. The correlation between parameter was analyzed by Karl Pearson correlation coefficient using SPSS 20.0. Results: The serum MDA levels (nmol/ml) were significantly higher in pre-diabetes (3.11±0.40) and diabetes mellitus (3.55±0.88) compared to normal controls (2.04±0.99). The SOD activity(U/ml) were lower in diabetes (7.69±3.83) and pre-diabetic subjects (8.13±2.15) compared to normal subjects (11.16±3.61). MDA has significant positive correlation with HbA1c and total cholesterol level. SOD has significant negative correlation with HbA1c and Total cholesterol/High Density Lipoprotein (TC/ HDL) ratio. Conclusion: The findings strongly confirmed that there is a continuous interplay between glycemic status, lipid peroxidation and hyperlipidemia in which one factor perpetuates another leading to the progression of disease.


Reproduction ◽  
2008 ◽  
Vol 136 (4) ◽  
pp. 491-502 ◽  
Author(s):  
M Ethier-Chiasson ◽  
J-C Forest ◽  
Y Giguère ◽  
A Masse ◽  
C Marseille-Tremblay ◽  
...  

The lectin-like oxidized low-density lipoprotein (LDL) receptor-1 (OLR1) is a newly described receptor for oxidatively modified LDL. The human pregnancy is associated with hyperlipidemia and oxidative stress. It has been reported that modification in maternal lipid profile can induce disturbance during pregnancy. In this study, we have evaluated the expression protein level of OLR1 in human term placenta of women having plasma cholesterol level lower to 7 mM or higher to 8 mM and women of gestational diabetes mellitus (GDM) by western blot analysis. The present study demonstrates that the maternal lipid profile is associated with placental protein expression of OLR1. A significant increase in the protein expression of OLR1 was observed in placenta of women with elevated plasmatic total cholesterol level (>8 mM). In addition, the placental protein expression of OLR1 is increased in mothers having the highest pre-pregnancy body mass index (BMI) and low (<7 mM) plasmatic total cholesterol level at term. Interestingly, the placental protein expression of OLR1 is increased in the presence of GDM pregnancies compared with normal lipids level pregnancies, without the modification of mRNA expression. In conclusion, placental OLR1 protein expression is associated with maternal lipid profile, pre-pregnancy BMI, and pathology of GDM.


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