scholarly journals Pola Konsumsi Makanan Sumber Yodium dan Goitrogenik dengan GAKY pada Anak Usia Sekolah di Ponorogo

2017 ◽  
Vol 1 (2) ◽  
pp. 88
Author(s):  
Imaniar Mahdiya Izati ◽  
Trias Mahmudiono

 Background: Iodine deficiency disorders (IDD) is one of nutritional problem in Indonesia. Inadequate intake of iodine and excessive goitrogenic intake is are main cause of IDD. Objectives: This study aimed to determine factors associated with IDD among schoolchildren. Methods: This study was an observational analytic with case control design in Sidoharjo Village, Jambon Sub District, Ponorogo on May 2017. The sample was 62 students from the first – sixth grade of SDN IV Krebet. They are consist of 31 students suffer IDD and 31 students with non IDD measured from goiter palpation. The data was collected by interview using questionnaire, iodine and goitrogenic consumption using FFQ. Data were analyzed by using chi square, fisher exact, spearman correlation and logistic regression. Results: Dietary iodine source that are rarely consumed is seafood (79,03%). Dietary goitrogenic source that are often consumed is tiwul (48,39%). Logistic regression analysis showed that seafood intake is the most influence factor of IDD (p= 0,011). Conclusion: There was a relation between iodine intake and goitrogenic intake with IDD among school children. Meanwhile, there is no association between characteristic of family with IDD among school children.ABSTRAK Latar Belakang: Gangguan Akibat Kekurangan Yodium (GAKY) merupakan salah satu masalah yang ada di Indonesia hingga saat ini. Rendahnya asupan yodium dan tingginya konsumsi sumber goitrogenik adalah penyebab terjadinya GAKY.Tujuan: Untuk mengetahui faktor yang berhubungan terhadap kejadian GAKY pada anak usia sekolah.Metode: Penelitian ini merupakan penelitian observasional analitik dengan desain case control dan dilakukan di Desa Sidoharjo, Kecamatan Jambon, Kabupaten Ponorogo pada bulan Mei 2017. Sampel penelitian ini yaitu siswa SDN IV Krebet dari kelas I-VI yang terdiri dari 62 siswa dimana 31 siswa menderita GAKY dan 31 siswa tidak menderita GAKY yang didapatkan dari hasil pemerikasaan palpasi. Pengumpulan data dilakukan menggunakan metode wawancara dengan kuesioner dan FFQ untuk mengetahui pola konsumsi makanan sumber yodium serta goitrogenik. Data dianalisis menggunakan chi square, fisher exact, korelasi spearman dan regresi logistik.Hasil: Makanan sumber yodium yang jarang dikonsumsi oleh responden adalah ikan laut (79,03%). Sedangkan makanan sumber goitrogenik yang sering dikonsumsi oleh responden adalah tiwul (48,39%). Hasil uji regresi logistik menunjukkan bahwa faktor yang paling berpengaruh terhadap kejadian GAKY yaitu pola konsumsi ikan laut (p= 0,011).Kesimpulan: Terdapat hubungan antara pola konsumsi ikan laut, pola konsumsi telur dan pola konsumsi tiwul dengan kejadian GAKY. Sebaliknya tidak terdapat hubungan antara karakteristik keluarga dengan kejadian GAKY.  

2017 ◽  
Vol 1 (2) ◽  
pp. 88 ◽  
Author(s):  
Imaniar Mahdiya Izati ◽  
Trias Mahmudiono

 Background: Iodine deficiency disorders (IDD) is one of nutritional problem in Indonesia. Inadequate intake of iodine and excessive goitrogenic intake is are main cause of IDD. Objectives: This study aimed to determine factors associated with IDD among schoolchildren. Methods: This study was an observational analytic with case control design in Sidoharjo Village, Jambon Sub District, Ponorogo on May 2017. The sample was 62 students from the first – sixth grade of SDN IV Krebet. They are consist of 31 students suffer IDD and 31 students with non IDD measured from goiter palpation. The data was collected by interview using questionnaire, iodine and goitrogenic consumption using FFQ. Data were analyzed by using chi square, fisher exact, spearman correlation and logistic regression. Results: Dietary iodine source that are rarely consumed is seafood (79,03%). Dietary goitrogenic source that are often consumed is tiwul (48,39%). Logistic regression analysis showed that seafood intake is the most influence factor of IDD (p= 0,011). Conclusion: There was a relation between iodine intake and goitrogenic intake with IDD among school children. Meanwhile, there is no association between characteristic of family with IDD among school children.ABSTRAK Latar Belakang: Gangguan Akibat Kekurangan Yodium (GAKY) merupakan salah satu masalah yang ada di Indonesia hingga saat ini. Rendahnya asupan yodium dan tingginya konsumsi sumber goitrogenik adalah penyebab terjadinya GAKY.Tujuan: Untuk mengetahui faktor yang berhubungan terhadap kejadian GAKY pada anak usia sekolah.Metode: Penelitian ini merupakan penelitian observasional analitik dengan desain case control dan dilakukan di Desa Sidoharjo, Kecamatan Jambon, Kabupaten Ponorogo pada bulan Mei 2017. Sampel penelitian ini yaitu siswa SDN IV Krebet dari kelas I-VI yang terdiri dari 62 siswa dimana 31 siswa menderita GAKY dan 31 siswa tidak menderita GAKY yang didapatkan dari hasil pemerikasaan palpasi. Pengumpulan data dilakukan menggunakan metode wawancara dengan kuesioner dan FFQ untuk mengetahui pola konsumsi makanan sumber yodium serta goitrogenik. Data dianalisis menggunakan chi square, fisher exact, korelasi spearman dan regresi logistik.Hasil: Makanan sumber yodium yang jarang dikonsumsi oleh responden adalah ikan laut (79,03%). Sedangkan makanan sumber goitrogenik yang sering dikonsumsi oleh responden adalah tiwul (48,39%). Hasil uji regresi logistik menunjukkan bahwa faktor yang paling berpengaruh terhadap kejadian GAKY yaitu pola konsumsi ikan laut (p= 0,011).Kesimpulan: Terdapat hubungan antara pola konsumsi ikan laut, pola konsumsi telur dan pola konsumsi tiwul dengan kejadian GAKY. Sebaliknya tidak terdapat hubungan antara karakteristik keluarga dengan kejadian GAKY.  


2018 ◽  
Vol 3 (3) ◽  
pp. 575
Author(s):  
Neila Sulung ◽  
Rizki Yananda ◽  
Adriani Adriani

<p>Cancer is one of the leading causes of death worldwide. In Indonesia every year 1: 3 women per 1000 population are affected by breast cancer. Breast cancer is a cancer that attacks most women. The incidence of breast cancer is currently estimated at 39 per 100,000 population in 2008. The purpose of this study was to determine the factors associated with the risk of female breast cancer in surgical outpatient poly patients at Dr. Achmad Mochtar, Bukittinggi City. This study uses descriptive analytic method with a case control approach. The sampling technique in this study was accidental sampling. The sample in this study were all women diagnosed with breast cancer, amounting to 50 cases and 50 controls with data processing through computerization. The instrument used in this study is a questionnaire. Data analysis was performed using Chi-Square test (α = 0.05). The results showed that the factors associated with the incidence of breast cancer were genetic (p = 0.009), menarche (p = 0.014), menopause (p = 0.016), hormonal contraception (p = 0,045), obesity (p = 0,043), and high food fat (p = 0.028).  Conclusions of the study are factors related to the risk of breast cancer incidence are genetic, menarche, menopause, hormonal contraception, obesity and high-fat foods.<br /> </p><p>Penyakit kanker merupakan salah satu penyebab kematian utama di seluruh dunia. Di Indonesia setiap tahun 1:3 wanita per 1000 penduduk terserang kanker payudara. Kanker payudara merupakan kanker yang paling banyak menyerang perempuan. Angka kejadian kanker payudara saat ini diperkirakan 39 per 100.000 penduduk pada tahun 2008. Tujuan penelitian ini adalah untuk mengetahui faktor-faktor yang berhubungan dengan risiko kanker payudara wanita pada pasien poli rawat jalan bedah di RSUD Dr. Achmad Mochtar Kota Bukittinggi. Penelitian ini menggunakan metode <em>deskriptif analitik</em> dengan pendekatan <em>case control</em>. Teknik pengambilan sampel dalam penelitian ini adalah <em>accidental sampling.</em> Sampel dalam penelitian ini adalah semua wanita yang terdiagnosis kanker payudara, berjumlah 50 kasus dan 50 kontrol dengan pengolahan data melalui komputerisasi. Instrument yang digunakan dalam penelitian ini adalah lembar kuisioner. Analisis data dilakukan menggunakan uji <em>Chi-Square </em>(α=0,05). Hasil penelitian menunjukkan faktor yang berhubungan dengan kejadian kanker payudara adalah genetik (p=0,009), <em>menarche</em> (p=0,014;), <em>menopause</em> (p=0,016), kontrasepsi hormonal (p=0,045), <em>obesitas </em>(p=0,043), dan makanan tinggi lemak (p=0,028). Simpulan penelitian adalah faktor yang berhubungan dengan risiko kejadian kanker payudara adalah genetik, <em>menarche, menopause,</em> kontrasepsi hormonal, <em>obesitas</em> dan makanan tinggi lemak.</p>


Author(s):  
Alfi Tri ◽  
Untung S. Widodo ◽  
Toto Sudargo

ABSTRACT<br /><br />Background: Iodine Defi ciency Disorder (IDD) is a health problem that affects quality of human resources. IDD happens not only due to iodine defi ciency but also other disorders such as goitrogenic substance (thiocyanate), pollutants of heavy metals (Pb) and micronutrient defi ciency (Fe) that inhibit thyroid hormone biosynthesis which cause the sweling of goitre glands.<br /><br />Objective: To identify the association between consumption of iodine, thiocyanate, Fe consumption, status of anemia and Pb and status of IDD in pregnant mothers at Subdistrict of Tabunganen, District of Barito Kuala, Province of Kalimantan Selatan.<br /><br />Method: The study was observational using case control design and quantitative method. Data were obtained through the palpation of goitre glands, measurement of thyroid stimulating hormone (TSH) level using ELISA method, iodine and thiocyanate consumption using food recall 2x24 hours and food frequency questionnaire (FFQ), Fe consumption using FFQ, Hb level using photometric method and Pb level using AAS method. Data were analysed by using chi-square and logistic regression.<br /><br />Result: There was signifi cant association (p&lt;0.05) between consumption of iodine (fi sh) based on FFQ and IDD status (goitre) with OR=3.44 and IDD status (TSH) with OR=8.00. There was no association between consumption of thiocyanate and Fe measured with food recall, FFQ and IDD status (goitre and TSH). There was signifi cant association (p&lt;0.05) between Pb status and IDD status (TSH) with OR=9.35.<br /><br />Conclusion: There was association between iodine consumption based on FFQ (fi sh) and IDD status (goitre) after the control of iodine consumption status (food recall). There was association between iodine consumption status (FFQ) in fi sh together with anemia status and the prevalence of IDD disorder (TSH) after the control of Pb status. <br /><br />KEYWORDS: iodine defi ciency disorder, pregnant mothers, iodine, thiocyanate, Fe, anemia, Pb<br /><br />ABSTRAK<br /><br />Latar Belakang: Gangguan akibat kekurangan yodium (GAKY) merupakan masalah kesehatan yang dapat mempengaruhi kualitas sumber daya manusia. GAKY tidak hanya disebabkan oleh kekurangan yodium, tetapi juga dipengaruhi oleh zat goitrogen(tiosianat), logam berat Pb, dan kekurangan Fe yang menghambat biosintesis hormon dan berakibat pada pembesaran kelenjar gondok.<br /><br />Tujuan: Mengetahui hubungan antara tingkat konsumsi yodium, goitrogen (golongan tiosianat), Fe, serta status anemia dan status Pb dalam darah dengan status GAKY pada ibu hamil di  Kecamatan Tabunganen Kabupaten Barito Kuala Provinsi Kalimantan Selatan.<br /><br />Metode: Penelitian ini merupakan penelitian observasional dengan rancangan case control. Data pembesaran kelenjar tiroid diperiksa denganpalpasi di daerah kelenjar tiroid, kadar TSH dengan metode ELISA, tingkat konsumsi yodium dan tingkat konsumsi tiosianat dengan metode food recall 2 x 24 jam dan food frequency questionnaire  (FFQ), tingkat konsumsi Fe dengan FFQ, kadar Hb dalam darah dengan metode fotometrik, kadar Pb darah dengan metode AAS.Data dianalisis menggunakan chi-square dan logistic regression.<br /><br />Hasil: Ada hubungan signifi kan (p&lt;0,05) antara tingkat konsumsi yodium (ikan laut) berdasarkan FFQ dan status terhadap status GAKY (gondok) dengan OR=3,44 dan status GAKY (TSH) dengan OR=8,00.Tidak ada hubungan antara tingkat konsumsi tiosianat dan Fe yang diukur dengan food recall, FFQ, dan status GAKY (gondok dan TSH). Antara status Pb dan status GAKY (TSH) juga tidak ditemukan adanya hubungan dengan OR=9,35.<br /><br />Kesimpulan: Ada hubungan antara konsumsi yodium berdasarkan FFQ (ikan laut) dan status GAKY (gondok) dan antara konsumsi yodium (FFQ) dengan status anemia dan prevalensi GAKY (TSH).<br /><br />KATA KUNCI: gangguan akibat kekurangan yodium, wanita hamil, yodium, tiosianat, Fe, anemia, Pb


2020 ◽  
Vol 48 (4) ◽  
pp. 271-280
Author(s):  
Utami Dwipayanti

Diarrhea remains an important health issues in Klungkung Regency. Community Based Total Sanitation Program (STBM) is a national program that aims to reduce diarrhoea incidence by changging people’s sanitation behavior. The objective of the research is to examine factors related to the aspect of pilar 1, 2 and 3 of STBM program towards diarrhea case among children under five in the catchment area of Puskesmas Banjarangkan II, Klungkung. This research is an observasional research with case control design on 37 mothers of children with diarrhea as cases and 37 controls. Demographic information, access and practice related to pilar 1,2,3 of STBM were collected using questionnaire developed based on STBM verification form. The data was analysed using Chi Square test and logistic regression. Aspects of Pillars 1,2 and 3 STBM program significantly associate with diarrhea incidence among children under five in Banjarangkan II Health Center catchment area, namely the quality of toilet and hand washing facilities, and hand washing with soap behavior at five critical. The logistic regression shows that determinants of diarrhea include the quality of toilet (AOR= 12.08), the quality of hand washing facilities (AOR= 9,43) and hand washing with soap behaviour before taking care and feeding the infant (AOR= 9,88). It is recommended for future implementation and monitoring of STBM program to emphasise more on the hygienic quality of toilet and hand washing facilities, as well as the hand washing behaviour in five critical times beside on the time after defecating. Keywords : diarrhea, hand washing, food hygiene, toilet, total sanitation Abstrak Diare masih menjadi salah satu masalah kesehatan masyarakat di Kabupaten Klungkung. Program Sanitasi Total Berbasis Masyarakat (STBM) merupakan salah satu program yang bertujuan menurunkan kejadian diare dengan mengubah perilaku sanitasi masyarakat. Penelitian ini bertujuan untuk mengetahui faktor Aspek Sanitasi Total Berbasis Masyarakat (STBM) Pilar 1, 2 dan 3 terhadap kejadian diare pada balita di wilayah Puskesmas Banjarangkan II di Kecamatan Banjarangkan Kabupaten Klungkung. Penelitian ini merupakan penelitian analitik observasional dengan desain Case Control yang dilakukan terhadap 37 ibu balita sebagai kasus dan 37 ibu balita sebagai kontrol. Informasi demografi, akses dan praktik terkait pilar 1,2,3 STBM dikumpulkan menggunakan kuisioner yang dikembangkan berdasarkan formulir verifikasi STBM. Data dianalisis menggunakan uji Chi Square dan regresi logistik. Aspek STBM pilar 1,2 dan 3 yang berhubungan bermakna terhadap kejadian diare pada balita di wilayah Puskesmas Banjarangkan II yaitu kualitas sarana sanitasi jamban, kualitas sarana Cuci Tangan Pakai Sabun (CTPS), dan kebiasaan mencuci tangan pakai sabun di 5 waktu kritis. Analisis regresi logistik menunjukkan determinan kejadian diare di wilayah studi adalah kualitas sarana jamban (AOR= 12.08), kualitas sarana CTPS (AOR= 9,43) dan kebiasaan mencuci tangan pakai sabun sebelum mengurus dan memberi makan balita(AOR= 9,88). Penekanan terhadap kualitas sarana sanitasi dan CTPS, serta perilaku CTPS di 5 waktu kritis selain setelah BAB sangat perlu dilakukan dalam program lebih lanjut. Kata kunci: diare,cuci tangan, higiene makanan, jamban,sanitasi total


2007 ◽  
Vol 74 (4) ◽  
pp. 301-305
Author(s):  
D.M. Aguiar ◽  
G.T. Cavalcante ◽  
M.B. Labruna ◽  
S.A. Vasconcellos ◽  
A.A.R. Rodrigues ◽  
...  

ABSTRACT The seroprevalence of Brucella spp. and the possible associated risk factors were estimated for 2,109 adult cows in Monte Negro county, State of Rondônia, Brazil. A questionnaire was completed for each farm where cattle were sampled. Laboratory tests were Rose-Bengal Agglutination, Standard Tube agglutination, and Mercaptoethanol. The adjusted overall prevalence of Brucella spp. seropositive cows for Monte Negro county was 15% and at least 54 herds (63%) were positive. A logistic regression analysis suggested that the herd size of more than 25 cows and the presence of pigs were significant factors associated with the seropositivity (herd size: OD = 2.8; P=0.02; presence of pigs: OD = 2.5; P =0.04). Other significant variables associated to the infection, analysed by Chi-Square were the presence of seropositivity cows with the herd that were repeat breeders and birth of weak calves (P < 0.05).


2019 ◽  
Vol 4 (1) ◽  
pp. 162
Author(s):  
Harisnal Harisnal ◽  
Dina Ediana

<p><em>The incidence of measles in the city of Bukittinggi has increased in 2016, namely 77 cases, 40 cases (51.9%) among them in infants. The initial survey of 10 samples found that 40% experienced measles, 50% never had measles immunization, 70% said they did not give exclusive breastfeeding when they were babies. The aim of the study was to determine the factors associated with measles in children under five. Analytical research method with case control design. The population of all children under five, suffering from measles in 2016 was 40 people. Samples were taken by total sampling, and control samples were taken matching. Data was collected through guided interviews and observations, and data was processed computerically with chi-square statistical tests. The results of univariate analysis revealed that 66.7% of the samples were in the control group (66.7%), measles immunization, 73.3%, exclusive breastfeeding, and 57.5% had densely populated homes. Bivariate results, there was a relationship between immunization status ( p = 0,000 and OR = 10.7), exclusive breastfeeding (p = 0.034 and OR = 2.667) and occupancy density (p = 0.003 and OR = 3.807). It was concluded that the factors associated with the incidence of measles were immunization status, exclusive breastfeeding and occupancy density. There needs to be counseling about the disease, continuity from the officers so that the community understands and is aware of the importance of efforts to prevent measles.</em></p><p> </p><p>Kejadian penyakit campak di Kota Bukittinggi mengalami peningkatan pada tahun 2016, yaitu 77 kasus, 40 kasus (51,9 %) diantaranya pada balita. Survei awal terhadap 10 sampel, didapatkan bahwa 40% mengalami kejadian campak, 50% tidak pernah melakukan imunisasi campak, 70% mengatakan tidak memberikan ASI eksklusif saat bayi, Tujuan penelitian untuk mengetahui faktor-faktor yang berhubungan dengan kejadian campak pada anak usia balita. Metode penelitian analitik dengan desain case control. Populasi seluruh anak usia balita, menderita penyakit campak pada tahun 2016 sebanyak 40 orang. Sampel diambil secara total sampling, dan sampel kontrol diambil secara matching. Data dikumpulkan melalui wawancara terpimpin dan observasi, dan data diolah secara komputerisasi dengan uji statistik chi-square. Hasil analisis univariat diketahui 66,7 % sampel merupakan kelompok kontrol, (66,7 %),  imunisasi  campak, 73,3 %, ASI eksklusif , dan 57,5 % memiliki rumah padat penghuni.Hasil bivariat, adanya hubungan antara status imunisasi (p=0,000dan OR =10,7), pemberian ASI eksklusif (p=0,034dan OR =2,667) dan kepadatan hunian (p=0,003dan OR =3,807). Disimpulkan faktor yang berhubungan dengan kejadian campak adalah status imunisasi, pemberian ASI eksklusif dan kepadatan hunian.Perlu adanya penyuluhan tentang penyakit, berkesinambungan dari petugas sehingga masyarakat lebih memahami serta menyadari tentang pentingnya upaya pencegahan penyakit campak.</p>


2019 ◽  
Vol 3 (2) ◽  
pp. 74-81
Author(s):  
Siti Surya Indah Nurdin ◽  
Dwi Nur Octaviani Katili ◽  
Zul Fikar Ahmad

Latar belakang: Stunting merupakan retardasi pertumbuhan linier kurang dari standar menurut usianya. Masalah stunting masih merupakan salah satu masalah terbesar di Kabupaten Gorontalo. Tujuan penelitian: Diketahuinya pengaruh faktor ibu, pola asuh, dan variasi MPASI terhadap kejadian stunting di Kabupaten Gorontalo. Metode: Desain penelitian menggunakan Case Control Study. Seluruh balita di Kabupaten Gorontalo menjadi Populasi studi. Sampel kasus merupakan balita yang menderita stunting, dan sampel kontrol adalah balita normal. Jumlah sampel sebanyak 118 balita. Sampel kasus dipilih dengan menggunakan purposive sampling dan sampel kontrol dipilih menggunakan random sampling. Data dianalisis dengan menggunakan uji Chi Square dan Logistic Regression. Hasil: pola asuh (OR = 3,901, 95% CI 1,692 – 8,994), variasi MPASI (OR = 3,260, 95% CI 1,371 – 7,750), riwayat KEK (OR = 2,482, 95% CI 1,013 – 6,081) dan pendidikan ibu (OR = 2,345, 95% CI 1,007 – 5,456). Umur ibu, pemberianASI Ekslusif, makanan pendamping ASI (MPASI), konsumsi snak hampir tiap hari, dan konsumsi mie instan 3 kali dalam seminggu bukan merupakan faktor risiko kejadian stunting. Simpulan: Faktor ibu yaitu pendidikan ibu, riwayat KEK, pola pemberian MPASI, dan pola asuh merupakan faktor risiko kejadian stunting.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Chien-Yi Wu ◽  
Chun-Hao Jen ◽  
Yun-Shiuan Chuang ◽  
Tzu-Jung Fang ◽  
Yu-Hsuan Wu ◽  
...  

Abstract Background With a rapidly aging population, there is an increasing need for do-not-resuscitate (DNR) and advance care planning (ACP) discussions. This study investigated the factors associated with signing DNR documents of older patients in the geriatric ward. Methods We conducted a retrospective cohort study at a geriatric ward in a tertiary hospital in Southern Taiwan. Three hundred and thirty-seven hospitalized older patients aged ≥65 years in the geriatric ward from 2018 to 2019. The Hospital Information System and electronic medical records were accessed to obtain details regarding patients’ demographics, daily living activities, serum albumin level, nutrition screening score, intensive care unit transferal, resuscitation procedure, days of hospital stay, and survival status on discharge, and DNR status was recorded retrospectively. Patients were classified into DNR and non-DNR groups, with t-tests and Chi-square tests applied to compare the differences between groups. Logistic regression was performed to predict factors related to the DNR documents. Results A total of 337 patients were included, 66 of whom had signed a DNR during hospitalization. After multivariate logistic regression, age 85 or more compared to age 65–74 (adjusted odds ratio, aOR 5.94), poor nutrition with screening score two or more (aOR 2.71), albumin level less than 3 (aOR 3.24), Charlson Comorbidity Index higher than 2 (aOR 2.46) and once transferred to ICU (aOR 5.11) were independently associated with DNR documentation during hospitalization. Conclusions Several factors related to DNR documents for geriatric patients were identified which could provide clinical information for physicians, patients, and their families to discuss DNR and ACP.


2021 ◽  
Author(s):  
Hu chen ◽  
Yang hong ◽  
Bai yu ◽  
Li ruiqian ◽  
Li Jun ◽  
...  

Abstract Background: The pathological diagnosis of bladder cancer workup relies on cystoscopy, however, due to sampling restriction, the depth of local invasion is often understaged. Methods: A total of 386 patients with bladder urothelial carcinoma underwent follow-up. The data collected included age, sex, tumor size, surgical options, histologic grade, invasive depth, lymph node metastasis, and oncological outcomes, and the patients were divided into coral-like and crumb-like groups. These data were analyzed with the chi-square test, binary logistic regression, Kaplan-Meier analysis, univariable and multivariable logistic regression and Spearman correlation test. Results: Bladder tumor morphology was moderately correlated with invasion depth (ρ=0.492, p<0.001; Spearman correlation), which was associated with invasion status (HR = 8.27; 95% CI: 4.3–15.79, p<0.001). Tumor morphology was not an independent factor for OS but was associated with PFS. Outer invasion depth was an independent factor that was significantly associated with inferior OS and PFS. Conclusions: Tumor morphology (coral-like and crumb-like) under cystoscopy was related to the depth of invasion. The outer invasive depth of BC was an independent factor that was significantly associated with inferior OS and PFS.


2014 ◽  
Vol 2 (1) ◽  
pp. 71
Author(s):  
Feranita Utama ◽  
Chatarina Umbul Wahjuni ◽  
Santi Martini

ABSTRACTThe government had held sub-national diphtheria immunization days in 2012 to combat an outbreak of diphtheria in East Java province. However, there werestill regencies or cities which had high incidence and Bangkalanregencywas the highest. The research aimed to analyze the determinants of diphtheria in Bangkalan after SNIDs. This research was case control study with 31 subjects as case and 124 as control spread in 25 case villages and 25 control villages. Bivariate analysis used chi-square and simple logistic regression. Multivariate analysis used logistic regression. Bivariate analysisresult showed that individual and household variables that had associate with incidence of diphtheria in the Bangkalan after SNIDs of diphtheria vaccine in 2012 were DPT immunization status, the status of SNIDs, age, and mother's education level. In this study, there were not associate between village variables with diphtheria in the Bangkalan after SNIDs. Multivariate analysis result showed that had associate with incidence of diphtheria in Bangkalan after SNIDs were no DPT immunization (p=0,012; OR=4,765), incomplete DPT immunization (p=0,001; OR=6,276), 3-7 years of age (p=0,014; OR=15,137), 7-15 years of age (p=0,001;OR=41,984), and no immunization in SNIDs (p=0,020; OR=3,553). Conclusion, the dominantfactors that affected diphtheriainBangkalanwere status of DPTimmunization, ageand the SNIDs of diphtheria. Recommendation, DPTimmunizationshould becomplete, boosterimmunization should be needed, monitoring theimplementation ofsubPIN should be strict, especially inschool, and thecoverage ofDPT3andsubPIN should be increased and its report should be improved.Keywords: diphtheria, sub-nationaldiphtheriaimmunization days, DPT                              immunization


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