THE RELATIONSHIP BETWEEN THE LONG IN HEMODIALIZATION WITH STATUS OF EXCESS VOLUME OF LIQUID IN CHRONIC KIDNEY FAILURE PATIENTS

2021 ◽  
Vol 2 (2) ◽  
pp. 147
Author(s):  
Susilo Harianto ◽  
Hafna Ilmy Muhalla ◽  
Devi Purbandari Regita Cahyani

Chronic kidney disease is a chronic disease that progresses damage to the kidneys which disrupts the body’s fluid and electrolyte balance which affects all body systems. PGK is currently it is one of the many diseases that have become a concern in the world including in Indonesia. One phenomenon that often occurs is an increase in fluid volume between two times of dialysis. The purpose of this study was to find out the long relationship between hemodialysis and excess fluid volume status in patients with chronic renal failure in the Hemodialysis room at Ibnu Sina Gresik Hospital. This was an analytical study with a correlative analytic design. Data were collected by using the contingency coefficient. The result of this study shows that older respondents underwent <1 year of hemodialysis with excess fluid status >2,5 BB post HD as much 81,2%, which is more dominant than patients who undergo > 1-year hemodialysis with excess fluid status >2,5 BB post HD as much 58% of the total resulting in p-value 0,103 where p>0,05 so it can be concluded that there is no long relationship to undergo hemodialysis with excess fluid volume status in patients with chronic kidney disease. It is expected that patients undergoing hemodialysis can be more obedient to the recommended diet so that it does not cause other complications and can improve the quality of life patients

Ners Journal ◽  
2021 ◽  
Vol 1 (2) ◽  
Author(s):  
PUTRI

Chronic kidney failure or chronic kidney disease is a progressive deviation, kidney function that can not recover, where the body's ability to maintain metabolic balance, fluid and electrolytes, resulting in uremia. This condition is caused by chronic glomerulonephritis, pyelonephritis, uncontrolled hypertension, hereditary lesions, vascular abnormalities, urinary tract obstruction, diabetes, and infections. Today, chronic kidney disease is a disease whose prevalence continues to increase. World Health Organization (WHO) released data on growth in the number of patients with chronic kidney failure in 2013 increased by 50% from the previous year and in America the incidence of chronic kidney failure increased by 50% in 2014 and every year 200,000 Americans undergo hemodialysis Hemodialysis is one way to remove metabolic waste products in the form of a solution and water that is in the blood through a semipermeable membrane or called a dialyzer. The working principle of fluid transfer in hemodialysis is diffusion, osmosis, ultrafiltration and convection. Changes in fluid and electrolyte balance in Chronic Kidney Failure patients result in changes in salivary composition and flow (Fan, Zhang, Luo, Niu & Gu, 2013). In addition to changes in salivary composition and flow, patients with chronic renal failure also experience changes in dry mouth (xerostomia) due to increased ureum concentrations in the blood (Fan et al., 2013). Chewing Gum Xylitol is a candy that no artificial sweeteners activity of chewing gum, low-sugar two eggs approximately 10 minutes to 3x / day for 2 weeks would lead to mechanical stimulation and chemical that can move reflex saliva to stimulate the receptor that is monitored by the trigeminal nerve (V) and facial nerve (VII) as a taste. Sympathetic nerve stimulation will accelerate the secretion of all salivary glands in large quantities which can reduce the sensation of thirst that appears . From the results of research using the method of comparison in get , look the frequency of xerostomia before the intervention mostly dominated by xerostomia weight of 67% and the visible frequency of xerostomia after intervention largely dominated by xerostomia mild 67% , Based on the output "Test Statistics" in table 4.4 above, known p-value is 0,000. Because the value of 0.003 is smaller than <0.05, it can be concluded that "H0 is rejected", or in other words there is "Effectiveness of Chewing Gum Against Xerostomia in Chronic Kidney Disease Patients Who Underwent Hemodialysis at Batam Bros Initial Hospital in 2020


2020 ◽  
Vol 8 (1) ◽  
pp. 106
Author(s):  
Chauverim Jeremi Gotlieb Paath ◽  
Gresty Masi ◽  
Franly Onibala

Abstract: Chronic Kidney Disease is progressive and irreversible kidney dysfunction where the body fails to maintain metabolim and fluid and electrolyte balance. Hemodialysis therapy is one of managements of CKD. Disobedience may causing failure of the therapy so it can increase mortality and morbidity numbers. Purpose: The purpose of this research is to find out the correlation beetween family support and hemodialysis adherence of patients with CKD. Method: this study used descriptive Analytic with Cross Sectional Study approach. This study involved 50 respondents with Chronic Kidney Disease using the total sampling technique. Data collection was done through the questionnaire about family’s support and hemodialysis therapy adherence of patient of CKD. The result of this study showed a significant correlation with p value=0,000 (α<0,05). Conclusion: There is a significant correlation beetween family support and hemodialysis therapy adherence of patients with CKD. Further studies are suggested to do other research about specification of family’s support with the example instrumental support.Key Words:     Chronic Kidney Disease, Family Support, Hemodialysis Therapy      Adherence. Abstrak: Gagal ginjal kronis merupakan gangguan fungsi ginjal yang progresif dan ireversibel dimana tubuh gagal untuk mempertahankan metabolisme dan keseimbangan cairan dan elektrolit. Terapi hemodialisa adalah salah satu penanganan gagal ginjal kronis. Ketidakpatuhan dapat menyebabkan kegagalan terapi sehingga meningkatkan angka mortalitas dan morbiditas. Dukungan keluarga merupakan salah satu faktor penting dalam meningkatkan kepatuhan terapi. Tujuan: ujuan penelitian ini untuk mengetahui hubungan dukungan keluarga dengan kepatuhan terapi hemodialisa pada pasien GGK. Desain Penelitian: Penelitian ini menggunakan Deskriptif Analitik dengan pendekatan cross-sectional Study. penelitian ini menggunakan 50 responden  dengan menggunakan teknik total sampling. Pengumpulan data dilakukan menggunakan kuesioner tentang dukungan keluarga dan kepatuhan menjalani terapi hemodialysis pada pasien CKD. Hasil dari penelitian ini menunjukan hubungan yang signifikan dengan nilai p=0,000 yang berarti nilai p<α=0,05. Kesimpulan: Dapat disimpulkan bahwa ada hubungan yang bermakna antara dukungan keluarga dengan kepatuhan hemodialisa pada pasien GGK. Bagi peneliti selanjutnya disarankan untuk melakukan penelitian tentang dukungan keluarga yang lebih spesifik contohnya dukungan instrumental. Kata Kunci: Gagal Ginjal Kronis, Dukungan Keluarga, Kepatuhan Hemodialisa


2020 ◽  
Vol 1 ◽  
pp. 151-155
Author(s):  
Kuwat Susanto ◽  
Asiandi Asiandi

The incidence of Chronic Kidney Disease (CKD) is increasing every year. The prevalence of CKD patients in Indonesia is 0.2%. One of the management of CKD is hemodialysis. The benchmark of success in hemodialysis therapy in extending the life of the patient is a survival rate. Through this survival rate, it will be visible to see the duration of the patient can survive. Objective: This study aimed to determine the factors which affected the survival time of Chronic Kidney Disease patients undergoing hemodialysis in Banyumas Regional Hospital. This study implemented an observational analytic design. This research type was a retrospective cohort. This study involved 275 respondents selected through simple random sampling technique. The setting of the study was in the Hemodialysis Room of Banyumas Regional Hospital. Research variables were tested by Kaplan meier method. The analysis indicated that the occupation and vascular access significantly affect the survival rate of patients with the Chronic Kidney disease. The result of the significance (p-value) was smaller than 0.05.There is a correlation between factors that affected the survival rate and the time of life resistance of CKD patients undergoing hemodialysis at Banyumas Regional Hospital, which are occupation and vascular access.


Author(s):  
Jimmy Chua ◽  
Yohanes Firmansyah ◽  
William Gilbert Satyanegara ◽  
Alexander Halim Santoso ◽  
Ernawati Su

In 2006, the Indonesian Renal Registry (Pernefri) shows about 12,5% of people in Indonesia suffer from chronic kidney disease. The most common cause of chronic kidney disease in 2018 in Indonesia is 39% by renal hypertension and 22% by Diabetic Nephropathy. This cross-sectional study was conducted at "RT" Hospital in Jakarta from 2018 to 2019. The Independent variable in this research was comorbid hypertension and obedience treatment, whereas dependent variables were risk category for kidney deterioration progression and the causal relationship tested with Pearson Chi-Square and Fisher exact as an alternative test. The study included 26 respondents, with 17 (65.4%) patients having hypertension in diabetic nephropathy. Eighty percent of respondents who did not routinely seek treatment in the hypertension group had progression from kidney failure to the Deep Red (Highest Risk) category. Fisher Exact statistical test analysis in the group with a history of comorbidities in the form of hypertension found no significant relationship between non-routine treatment with the progression of chronic kidney failure in the Highest-Very Highest Risk category (p-value = 0.515). Still, a large risk was found in the non-group routine treatment with a chance of 1.33 (0.962 - 1.848) times to have the progression of chronic kidney failure in the category of Highest-Very Highest Risk. Can be concluded that controlling blood pressure and treatment proven to slow worsening kidney function in nephropathy diabetic, even though no significant relationship has been found due to lack of sample. Keywords: diabetic nephropathy; hypertension; prognosis AbstrakPerhimpunan Nefrologi Indonesia (Pernefri) tahun 2006 merilis data penderita gagal ginjal kronis di Indonesia sebesar 12,5%. Etiologi terbesar gagal ginjal kroniks menurut Indonesian Renal Registry tahun 2018 adalah penyakit ginjal hipertensi sebesar 39% dan nefropati diabetic sebesar 22%. Potong lintang pada pasien di RS”RT” Jakarta tahun 2018-2019. Variabel bebas dalam penelitian ini adalah komorbid hipertensi dan kepatuhan berobat, sedangkan variable tergantung dalam penelitian ini berupa kategori risiko progresifitas perburukan ginjal serta hubungan sebab akibat diuji dengan Peason Chi Square dan uji alternatif Fisher Exact Test. Penelitian berlangsung mengikutsertakan 26 responden, dengan prevalensi hipertensi pada pasien nefropati diabetik sebesar 17 (65,4%). Delapan puluh persen responden yang tidak rutin berobat pada kelompok hipertensi memiliki progresifitas penyakit gagal ginjal hingga kategori Deep Red (Highest Risk). Analisa uji statistik Fisher Exact pada kelompok dengan riwayat penyakit penyerta berupa hipertensi didapatkan tidak hubungan yang bermakna antara tidak rutin berobat dengan progresifitas penyakit gagal ginjal kronis kategori Highest-Very Highest Risk (p-value = 0,515) tetapi secara besar risiko didapatkan bahwa kelompok yang tidak rutin berobat memiliki risiko 1,33 (0,962 – 1,848) kali untuk memiliki progresifitas penyakit gagal ginjal kronis kategori Highest-Very Highest Risk. Dapat disimpulkan bahwa engontrol tekanan darah dan rutinitas berobat dapat memperlambat perburukan fungsi ginjal akibat komplikasi lanjut dari nefropati diabetikum, walaupun belum didapatkan hubungan yang bermakan dikarenakan kurangnya besar sampel pada penelitian ini.


2018 ◽  
Vol 5 (2) ◽  
pp. 56-63
Author(s):  
Abdul Wakhid ◽  
Estri Linda Wijayanti ◽  
Liyanovitasari Liyanovitasari

Background: Self efficacy can optimize the quality of life of clients who undergo the healing process due to chronic diseases. Individuals with higher self-efficacy move their personal and social resources proactively to maintain and improve the quality and length of their lives so that they experience a better quality of life. Objectives: the purpose of this study was to find the correlation between self efficacy and quality of life of patients with chronic kidney disease who undergo hemodialysis at RSUD Semarang Regency. Metode: This type of research was descriptive correlation with cross sectional approach. The samples in this study more 76 people with total sampling technique. The data collection tool for self efficacy was measured by General Self-Efficacy scale, for quality of life with WHOQoL-BREF. Statistical test used Kolmogorov-smirnov. Result: The result showed that self efficacy in patients with chronic kidney disease was mostly in moderate category (53,9%), quality of life in patients with chronic kidney disease was mostly in good category (68,4%). There was a correlation between self efficacy and quality of life of patients with chronic kidney disease who undergo hemodialysis at RSUD Semarang Regency, the result obtained p-value of 0.000 <α (0,05). Suggestion: Patients with chronic kidney disease can maintain good quality of life by helping to generate positive self-esteem and high self efficacy.


2021 ◽  
pp. 75-76
Author(s):  
Bharat Bhushan ◽  
Debarshi Jana

Background: Dyslipidemia is very much common in chronic kidney disease patients and is responsible for cardiovascular disease (CKD) which is most common cause of mortality in them. So, it is necessary to study the lipid prole in CKD patients to prevent morbidity and mortality. Methods: Subjects each of 50 in number are grouped into healthy controls (group-1), CKD patients without hemodialysis (group-2), CKD patients with hemodialysis (group-3). After fasting of 12 hours, lipid prole is assessed in all cases. Results: In this study, there is increase in Total cholesterol (TC), Low Density lipoprotein (LDL), very Low-Density lipoprotein (VLDL) and Triglycerides (TG) and decrease in High Density Lipoprotein (HDL) in all CKD patients compared to healthy controls (p-value for each parameter <0.001). There is increase in TC, TG and VLDL in diabetic CKD patients compare to non-diabetic CKD patients and p-value for each parameter is <0.05. It was found that TG and VLDL increase and HDL decrease in group-3 compare to group-2 is statistically signicant (p-value for each <0.05) and no signicant variation in TC and LDL in these groups. Conclusions: Present study demonstrated that there is dyslipidemia in CKD patients irrespective of mode of management, but the derangement is much more common and signicant in CKD with hemodialysis group and they are at risk of cardiovascular disease. It is better to start lipid lowering drugs which decreases disease progression and dyslipidemia.


2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Pietro Manuel Ferraro ◽  
Alessandra Nicolosi ◽  
Alessandro Naticchia ◽  
Nicola Panocchia ◽  
Giuseppe Grandaliano ◽  
...  

Abstract Background and Aims Chronic kidney disease is a frequent condition, characterized, especially in its more advanced stages, by an array of derangements in bone structure and density, resulting in a higher rate of bone fractures. Current strategies to monitor the bone status and assess the risk of bone fractures in CKD patients are limited. The Bone Elastic Structure (BES) test is a recently-developed non-invasive tool that measures the elastic characteristics of the trabecular bone by simulating the application of loads on a virtual biopsy obtained from radiographic images of the proximal epiphyses in the patient’s hand fingers. The simulation results are combined to obtain a parameter defined Bone Structure Index (BSI). The aim of our study is to explore whether the BES test could be a useful monitoring tool of bone status in patients with CKD on dialysis by exploring whether such patients have different BSI values compared with persons without CKD. Method The BES test was performed on a sample of 41 patients undergoing chronic hemodialysis (HD) and the BSI compared with a group of 374 persons with normal renal function who had undergone the BES test in previous studies. Differences in BSI and 95% confidence intervals (CIs) between the two groups were obtained and tested for statistical significance with a linear regression model including BSI as the dependent variable and kidney status (HD vs no HD) as the independent variable, adjusted for age and sex. Subgroup effects were explored by including interaction terms (age x kidney status, age x sex, kidney status x sex) in the model. Finally, to further remove the potential confounding by age and sex, each HD patient was individually matched with up to 4 non-HD participants based on sex and age (with a 5-year caliper) and a matched analysis was conducted on BSI values. Results Average (SD) age was 64 (17) years in the HD group and 60 (12) years in the non-HD group, with a prevalence of males of 49% and 16%, respectively. The individual values of BSI divided by kidney status and sex in Figure. The multivariate linear regression model showed that, after adjustment for age and sex, the BSI in the HD group was significantly lower compared with the non-HD group (HD 145, 95% CI 140, 154; non-HD 179, 95% CI 177, 181; absolute difference −32, 95% CI −40, −25; p-value &lt; 0.001). There was no significant interaction between age, sex and kidney status on BSI values (all p-values &gt; 0.05). Individual matching was successful for 36 out of 41 HD patients, who were matched to 127 non-HD participants; matched analysis confirmed the results (absolute difference −31, 95% CI −40, −23; p-value &lt; 0.001). Conclusion The output of a non-invasive tool to determine the bone elastic structure appeared to be strongly associated with kidney function after control for differences in age and sex. Further studies are needed to determine the potential application of the BES test in patients with CKD.


2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Marzia Pasquali ◽  
Natalia De Martini ◽  
Lida Tartaglione ◽  
Silverio Rotondi ◽  
Marta Catalfamo ◽  
...  

Abstract Background and Aims Assuming that FGF23 levels correlate with phosphate excretion per nephron, nephron number can be estimated by measuring FGF23 levels and urinary phosphate excretion (FEP). Kuro-O proposed that the ratio of FEP to serum FGF23 levels should correlate with nephron number and is defined as the Nephron Index (NI). The aim of the study is calculating NI as nephron number estimation in patients affected by various degree of chronic kidney disease, both transplanted and not. Method In 147 CRF patients kidney function, mineral metabolism biomarkers and NI were evaluated. Nephron Index was calculated following Kuro-o’s equation (kuro-o 2019): NI=FEP·Ps·eGFRFGF23 Observed patients were divided into two groups: patients with CKD (noTX) and transplanted ones (TX). Results noTX group was made up of 67 patients (40 males and 27 females) affected by CKD stages from G1 to G5. TX group was composed by 80 patient (49 males and 31 females) with various degree of CKD (G1T-G4T) showing mean graft age of 83,2 ± 54,8 months (range: 10,3-268,0). The two groups differed for age (mean age 59 ± 15,6 years in CKD, 55± 10,3years in TX). Mean eGFR did not differ between TX and noTX but NI was higher in TX since FEP was higher despite lower FGF23 levels in TX. The difference in FGF23 levels does not appear to depend on Klotho and PTH whose serum levels were no different between Tx and noTx. (Table1). As far as correlations are concerned, NI correlated with eGFR, FGF23, PTH and 1,25D in both group, while NI correlated with FEP only in the TX group. It's interesting that no correlation existed between FGF23 and sP, FEP, eGFR and sKlotho in TX differently from noTX (Table2). Discussion. NI could not be properly defined as nephron number estimation in TX pts. However it may represent higher function of residual nephrons, since higher FEP did not correlate to FGF23 and could be determined by compensatory hyperfiltration (increased single nephron GFR) in transplanted patients. Conclusion After kidney transplantation, high NI value could have a functional meaning rather than represent residual number of nephrons.


2020 ◽  
Vol 2 (1) ◽  
pp. 1-8
Author(s):  
Bonifasius Hat ◽  
Rufina Hurai

Chronic Kidney Disease merupakan  gangguan fungsi ginjal yang progresif dan ireversibel, salah satu penanganannya dengan hemodialisa, keluhan yang sering pada pasien hemodialisa adalah kelelahan. Tujuan penelitian ini melihat pengaruh edukasi berbasis self care terhadap perubahan tingkat kelelahan pada pasien hemodialisa, merupakan penelitian kuantitatif dengan metode kuasi eksperimen pre post test design di RSUD A. Wahab Sjahranie periode Mei-Juni 2017, pengambilan sampel dilakukan  dengan cara purposive sampling melibatkan 111 responden yang dibagi menjadi 2 kelompok intervensi edukasi berbasis self care 83 orang dan kelompok kontrol 28 orang. Hasil penelitian ini didapatkan setelah dilakukan intervensi selama 6 minggu, Uji Beda Berpasangan Non Parametrik Independent menunjukan bahwa nilai Asymp Sig (2 tailed) = 0,000 atau p-value <  0,05  ada pebedaan tingkat kelelahan antara kelompok intervensi terhadap kelompok kontrol, nilai OR menunjukkan kelompok intervensi edukasi berbasis self care memiliki kecenderungan mengalami perubahan tingkat kelelahan 1,22 kali lebih besar dibandingkan dengan kelompok kontrol. Pada analisis uji logistik ordinal hasil menunjukkan nilai p = 0,00 atau p-value <0,05  ada pengaruh yang signifikan intervensi edukasi berbasis self care yang diberikan terhadap perubahan tingkat kelelahan. Simpulan penelitian edukasi berbasis self care mempunyai pengaruh terhadap perubahan tingkat kelelahan dan direkomendasikan intervensi ini dapat diaplikasikan sebagai salah satu edukasi yang diberikan pada pasien menjalani hemodialisa


2021 ◽  
Vol 10 (2) ◽  
Author(s):  
Ika Setyo Rini ◽  
Titik Rahmayani ◽  
Efris Kartika Sari ◽  
Retno Lestari

Background: Chronic kidney disease (CKD) is defined as a progressive disease that causes renal failure and requires extended and long-term therapies. CKD patients need to choose one of these therapies to improve their quality of life. This study aims to investigate differences in the quality of life of chronic kidney disease patients undergoing hemodialysis and continuous ambulatory peritoneal dialysis (CAPD).Design and Methods: The study design used is similar to the cross-sectional design. Therefore, in this study observations were carried out, a EQ_5D life quality questionnaire sheet was administered to respondents, and a purposive sampling method was used. The total number of respondents was 250 and consisted of 125 hemodialysis and CAPD patients each.Results: The results obtained using the Mann Whitney method was a p-value (0.515)> α (0.05). These results also included five components, namely the ability to move/walk to an acceptable degree, adequate self-care, performance of usual activities, minimal amount of pain/discomfort during hemodialysis and CAPD, and acceptable levels of anxiety/sadness.Conclusions: This research concludes that there is no difference in the quality of life between CKD patients  undergoing hemodialysis and CAPD.


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