A Cross-sectional Serological Study for Measles among Italian Medical Students in 2020

Background: Measles is an infectious disease and a major health concern worldwide. Among individuals with a higher risk of exposure to measles, there are the Health Care Workers (HCWs), who may transmit the virus to other people. According to the Italian National Plan for Immunization and Prevention, all HCWs should have presumptive evidence of immunity to measles (documented two doses of MMR vaccination) or serological evidence of protective antibodies. Aim: The study aims to evaluate the immunological status, the vaccine coverage, and the protective IgG antibody titre for measles in medical students of the teaching hospital PoliclinicoTor Vergata (PTV). Methods: IgG measles antibodies titre was evaluated in a sample of 461 medical students undergoing annual health surveillance visits from January 1st to May 31th, 2020. Results: 73.7% of medical students showed protective measles IgG antibody levels. The immunization rate was higher among subjects aged less than 25 years with respect to students aged over 25 years (77.4% vs. 66.4%; P <0,001). Furthermore, average antibody titre showed a statistically significant association with the age group (124,2 AU/ml for the age group 18-25 and 133,2 AU/ml among subjects aged 25 or more; P<0.001). Conclusion: Our study shows a non-protective measles IgG antibody titre, especially among the older students. Therefore, it is essential to evaluate the serological levels, to vaccinate those subjects whose antibody level is not adequate, and promote the vaccination even in the general population.

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Persistence of antibodies against Spike glycoprotein of SARS-CoV-2 in health care workers post double dose of BBV-152 and AZD1222 vaccines

10.21203/rs.3.rs-888762/v1 ◽

2021 ◽

Author(s):

Hari Ram Choudhary ◽

Debaprasad Parai ◽

Girish Chandra Dash ◽

Jaya Singh Kshatri ◽

Narayan Mishra ◽

...

Keyword(s):

Health Care ◽

Health Care Workers ◽

Serum Samples ◽

Igg Antibody ◽

Cross Sectional ◽

Post Vaccination ◽

Care Workers ◽

History Of ◽

Heath Care ◽

Antibody Levels

Abstract Rationale: Vaccine rollout in India was initiated in mid-January, 2021 and is supposed to be the only antidote against SARS-CoV-2 as of now.Objectives: To study the dynamicity of vaccine-induced IgG antibody against SARS-CoV-2.Methodology: The present cross-sectional cohort study was undertaken to determine IgG antibody among health care workers with completed dose of either Covaxin or Covishield and were followed for 24 weeks after first dose of either vaccine to record the periodic changes in titre, concentration, clinical growth and persistence of vaccine-induced SARS-CoV-2 antibodies.Results: Serum samples were collected from 614 participants during each follow-up and tested them in two CLIA-based platforms for testing SARS-CoV-2 antibodies both qualitatively and quantitatively. Among these participants, 308 (50.2%) were Covishield recipient and rest 306 (49.8%) took Covaxin. A total of 81 breakthrough cases was recorded among the cohort participants for whom infection post vaccination acted as booster. The rest 533 heath care workers without any history of post-vaccination infection showed significant antibody waning either from T3 (Covaxin recipient) or T4 (Covishield recipient).Conclusion: The clinical implications of waning antibody levels post vaccination are not well understood, and it remains crucial to establish S-antibody thresholds associated with protection against clinical outcomes.

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COVID-19 KNOWLEDGE, ATTITUDE, AND PRACTICES BETWEEN PAKISTANI MEDICAL AND NON-MEDICAL STUDENTS

Journal of University Medical & Dental College ◽

10.37723/jumdc.v12i3.641 ◽

2021 ◽

Vol 12 (3) ◽

pp. 169-176

Author(s):

Bushra Suhail ◽

Ayesha Masood ◽

Javaria Baig ◽

Sara Mukhtar ◽

Sarah Aftab ◽

...

Keyword(s):

Medical Students ◽

Conceptual Knowledge ◽

Demographic Data ◽

Healthcare Providers ◽

Cross Sectional Study ◽

Age Group ◽

Online Questionnaire ◽

Cross Sectional ◽

Contagious Nature ◽

Positive Attitudes

BACKGROUND & OBJECTIVE: This study investigated medical and non-medical students’ knowledge, attitude, and preparedness regarding COVID-19 pandemic, to groom volunteers and future healthcare providers in a better way. METHODOLOGY: This cross-sectional study was completed from April to May 2020 during the first wave of COVID-19. An online questionnaire was distributed using internet and social media (SM). The questionnaire was composed of several parts concerning to demographic data, knowledge, attitude, and practices. RESULTS: This study included 1851 students [1041(56.54% medical, 810(43.46%) non-medical students)]. Medical students had significantly better knowledge about the contagious nature, spread and treatment of coronavirus. Non-medical students showed more risky behavior compared to medical students (p = 0.005). The use of masks and the frequency of handwashing was better among medical students as compared to non-medical students (p< 0.001; p< 0.014, respectively). The odds ratio indicates that students of the age group 21-25 years (45%) and medical students (75%) were more likely to have a positive attitude. CONCLUSION: This study revealed good knowledge, positive attitudes, and good practices towards COVID-19 among medical students. Still, a minority of participants from both groups revealed misconceptions and relatively poor conceptual knowledge regarding the disease.

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Duration of immunity against COVID-19 after vaccination in Indian subcontinent

10.21203/rs.3.rs-1260289/v1 ◽

2022 ◽

Author(s):

Apoorva Munigela ◽

Sasikala M ◽

Gujjarlapudi Deepika ◽

Anand V Kulkarni ◽

Krishna Vemula ◽

...

Keyword(s):

Neutralizing Antibodies ◽

Booster Dose ◽

Indian Subcontinent ◽

Neutralizing Antibody ◽

Health Concern ◽

Mortality Data ◽

Optimal Timing ◽

Cross Sectional ◽

Mortality And Morbidity ◽

Antibody Levels

Abstract Coronavirus disease (COVID-19) continues to be a major health concern leading to substantial mortality and morbidity across the world. Vaccination is effective in reducing the severity and associated mortality. Data pertaining to the duration of immunity, antibody waning and the optimal timing of booster dose administration is limited. In this cross-sectional study, we assessed the antibody levels in healthcare workers who were fully vaccinated after obtaining Institutional ethics committee approval and informed consent. Whole blood was collected and enumeration of S1/S2 neutralizing antibody levels was carried out using LIAISON SARS-COV-2 S1/S2 IgG assay. A total of 1636 individuals who were vaccinated with Covaxin or Covishield were included. Of these, 52% were males with a median age of 29 years. Diabetes and Hypertension was noted in 2.32% (38/1636) and 2.87% (47/1636) of the individuals. Spike neutralizing antibodies were below the detectable range (<15 AU/ml) in 6.0% (98/1636) of the individuals. Decline in neutralizing antibody was seen in 30% of the individuals above 40 years of age with comorbidities (diabetes and hypertension) after 6 months. These individuals may be prioritized for a booster dose at 6 months.

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Effect of COVID-19 Lockdown on the Physical Activity and Lifestyle of Medical Students of University of Lahore

10.53350/pjmhs211592175 ◽

2021 ◽

Vol 15 (9) ◽

pp. 2175-2177

Author(s):

Khadija Ghafoor Quraishi ◽

Mian Ali Raza ◽

Sadaf Waris ◽

Fahad Tanveer ◽

Ashfaq Ahmad

Keyword(s):

Physical Activity ◽

Medical Students ◽

Sampling Technique ◽

Activity Level ◽

Health Concern ◽

Online Questionnaire ◽

Cross Sectional ◽

Low Level ◽

High Level ◽

The University

Background: COVID-19 pandemic has become a foremost health concern, many countries have ordered lockdown to stop the spread of COVID-19 due to which many Universities are closed and students are taking lectures online, Pakistan is also one of the countries in which lockdown was imposed, the aim of this study is to examine the level of physical activity and lifestyle of medical students from University of Lahore (UoL) during COVID-19. Aim: To determine the effect of COVID-19 lockdown on the physical activity and lifestyle of medical students of University of Lahore. Materials: Sample size included 151 medical students from the University of Lahore, study was pure cross-sectional and convenient sampling technique was used, data was collected through online questionnaire which contained question from IPAQ-SF to estimate the physical activity and lifestyle of observed University students. Data was analyzed using SPSS version 25. Results: The results showed that from the population of 151 medical students of University of Lahore 75 students (49.7%) reported Low level of physical activity, while 44 students (29.1%) students reported Moderate level of physical activity, and 32 students (21.2%) reported high level of physical activity. Conclusion: Majority of the medical students showed Low level of physical activity, 49.7% in the last 7 days during COVID-19 pandemic. Medical students of University of Lahore showed a decrease in their overall physical activity level. Keywords: COVID-19, lockdown, Medical students, Physical activity

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A STUDY TO ASSESS THE SEROPREVALENCE OF HEPATITIS B AND ANTI HBS ANTIBODY LEVELS AMONGST HEALTH CARE WORKERS AND MEDICAL STUDENTS.

10.36106/ijsr/8002609 ◽

2021 ◽

pp. 84-85

Author(s):

Aditya Rana ◽

Anuradha Sood

Keyword(s):

Medical Students ◽

Hepatitis B ◽

Healthcare Workers ◽

Base Material ◽

Hepatitis B Vaccination ◽

Continuous Exposure ◽

Cross Sectional ◽

Antibody Titres ◽

Antibody Titers ◽

Antibody Levels

Background: Hepatitis B(HBV) is a blood borne virus and it is one of the most important occupational hazards among healthcare workers (HCWs) & Medical students. This study aimed to measure the anti-HBs titres and to assess the seroprevalence of Hepatitis B in HCW and medical students. It was a prospective,descriptive and cross sectional hospital base Material and method: d study. Medical students and healthcare workers who had received all three doses of hepatitis B vaccination were included in the study. A total of 200 subjects , aged between 18 and Result: 62 years were taken. 182 were vaccinated and 18 were unvaccinated. 85 were males and 115 females. Seroprevalence of Hepatitis B was nil. Antibody titres were >100mIU/ml in 51.6% , 10-100mIU/ml in 16.4% & <10 mIU/ml in 31.8% respectively.Negative correlation of decreasing antibiotic titer and age was seen. HCW and medical students are at hi Conclusion: gher risk due to their continuous exposure to blood products. Vaccination should be compulsory to the HCW and medical workers in the institution as Hepatitis B is a preventable disease. Monitoring of antibody titers should be done from time to time to see waning off antibody titers after vaccination

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Profile of Hand Surgery Cases at Kirtipur Hospital

Journal of Nepalgunj Medical College ◽

10.3126/jngmc.v14i2.21537 ◽

2018 ◽

Vol 14 (2) ◽

pp. 41-43

Author(s):

Bikash Karki ◽

Kiran Nakarmi ◽

Mangal Gharti Magar ◽

Krishna Nagarkoti ◽

Shankar Man Rai

Keyword(s):

Birth Defects ◽

Reconstructive Surgery ◽

Hand Surgery ◽

Health Concern ◽

Age Group ◽

Hand Trauma ◽

Public Health Concern ◽

Cross Sectional ◽

Common Cause ◽

Male Preponderance

Background: There can be multiple hand problems with which patients can present. Such hand problems can be because of any kind of trauma, birth defects, tumours, infection or other conditions. Hand surgery is a special field of plastic surgery, which deals with these hand problems. The Department of Burns, Plastic & Reconstructive Surgery of Kirtipur Hospital run by Public Health Concern Trust-Nepal has been providing hand surgery service to the patients with these hand problems.Aim of Study: To analyse the various types of surgical hand problems in patients attending Kirtipur Hospital.Material and Methods: It is a cross sectional retrospective observational study of the patients with different hand problems done at the Department of Burns, Plastic & Reconstructive surgery of Kirtipur Hospital from January to December 2016.Results: There were 124 patients who presented with various hand problems. There was male preponderance and the most common age group affected was between 15-60 years. Hand trauma was the most common cause of hand problems followed by post burn contractures.Conclusion: Hand is a complicated organ which can give rise to various problems. Hand surgery is an essential component of reconstructive surgery to deal with these problems. JNGMC, Vol. 14 No. 2 December 2016, Page: 41-43

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Bordetella Pertussis Antibody Levels in DPT/Pentavalent Immunized Preschool Nigerian Children: A Cross-Sectional Study

Journal of Pediatric Infectious Diseases ◽

10.1055/s-0039-1693484 ◽

2019 ◽

Vol 15 (01) ◽

pp. 011-015

Author(s):

Glory Ekpo Bassey ◽

Emmanuel Eyo Ekanem ◽

Henry Chima Okpara ◽

Komomo Ibor Eyong

Keyword(s):

Pertussis Toxin ◽

Bordetella Pertussis ◽

Age Groups ◽

Booster Vaccination ◽

Rapid Decline ◽

Age Group ◽

Igg Antibodies ◽

Cross Sectional ◽

Nigerian Children ◽

Antibody Levels

AbstractPertussis is a vaccine-preventable disease and antibodies formed are known to decline with time. The aim of this study was to measure Bordetella pertussis/toxin immunoglobulin G (IgG) antibodies in different age groups of Nigerian children and determine the age at which booster dose may be required. A total of 422 children, aged 6 to 60 months, were tested for the presence of B. pertussis/toxin IgG antibodies by ELISA (enzyme-linked immune sorbent assay). The highest positivity rate was in the 6 to 11 months of age group, while the highest negativity rate was in the age group of 24 to 35 months. We conclude that B. Pertussis/toxin IgG antibodies response is weak in Nigerian children after three doses of DPT (diphtheria, pertussis, and tetanus)/pentavalent vaccination, and there is a rapid decline of antibody levels between 12 and 35 months. We recommend that booster vaccination should be given at 12 to 15 months of age.

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Rubella Immunity among Pregnant Women in Jeddah, Western Region of Saudi Arabia

Obstetrics and Gynecology International ◽

10.1155/2014/659838 ◽

2014 ◽

Vol 2014 ◽

pp. 1-6 ◽

Cited By ~ 10

Author(s):

Sharifa A. Alsibiani

Keyword(s):

Saudi Arabia ◽

Pregnant Women ◽

Natural Infection ◽

Screening Tests ◽

Age Group ◽

Vaccination Policy ◽

Cross Sectional ◽

Significant Difference ◽

Antibody Levels ◽

Rubella Vaccination

To determine the presence of rubella immunity among pregnant women attending their first prenatal visit in Jeddah, Saudi Arabia, a retrospective, descriptive, cross-sectional, hospital-based study (prevalence study) was undertaken. A total of 10276 women attending prenatal clinics between January 1, 2008, and December 31, 2011 were included. Rubella screening tests (immunoglobulins: IgG and IgM), rubella antibody titer levels, patient age, gravidity, parity, and the number of previous abortions were analyzed. No patients tested IgM positive, and 9410 (91.6%) were immune (IgG positive); the remaining 866 (8.4%) were susceptible. There were no significant differences in gravidity, parity, or the number of previous abortions between immune and nonimmune groups. In contrast, the immunity rate decreased with increasing age, with a significant difference between the youngest age group (15–19 years) and the oldest age group (40–49 years) (P=0.0005; odds ratio, 2.86; 95% confidence interval, 1.7–4.7). Rubella immunity among pregnant women was high (91.6%) but decreased significantly with increasing age. A possible explanation for this is the change in the rubella vaccination policy in Saudi Arabia in 2002, from 1 dose to 2 doses. In addition, antibody levels begin to decline after vaccination and natural infection.

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Knowledge of Healthcare Workers on Immunization: New and Under-utilized and Perception towards Future Vaccines

Journal of BioMedical Research and Clinical Practice ◽

10.46912/jbrcp.124 ◽

2019 ◽

Vol 2 (4) ◽

pp. 202-207

Author(s):

AM Jibo ◽

RS Karaye ◽

AU Gajida ◽

AA Abulfathi

Keyword(s):

Health Care ◽

Health Care Workers ◽

Health Workers ◽

Vaccine Coverage ◽

Sampling Technique ◽

Vaccine Uptake ◽

Good Knowledge ◽

Cluster Sampling ◽

Cross Sectional ◽

Care Workers

Nigeria is making effort to address the child mortality burden by increasing vaccine coverage rates, yet the vaccine coverage falls short of 90% target. Scaling up of new and under-used vaccines to 90% coverage could save more than 600,000 Nigerian children. Healthcare givers knowledge of vaccine used for immunization is essential to increase the vaccine uptake rates. This study assesses the knowledge of routine, underutilized and future vaccines among health workers. A cross sectional descriptive study was done among health care workers at a tertiary health facility in Nigeria. Using a pre-tested semi structured interviewer administered questionnaire, 220 respondents were selected by cluster sampling technique. The health workers’ knowledge of these vaccines was assessed using a scale developed for the study. Data collected were analyzed using SPSS version 22.The mean age of the respondents was 31.9 + 5.7 years . Doctors and nurses formed more than half of the respondents, 51.8% (n=114). About three quarters of respondents 72.3% (n=159) had good knowledge of vaccines used in routine immunizations. Knowledge of under-utilized and future vaccine was low with less than a fifth 18.6% (n=41) and one tenth 9.1% (n=20) having good knowledge scores respectively. Similarly, poor perception scores of future vaccines were observed in 90.1% (n=218) of the respondents. Only marital status was associated with knowledge of underutilized vaccines (p<0.05) and no association was observed between other sociodemographic variables and knowledge of these vaccines (P>0.05). The awareness level of health care workers on routine immunization is high. Their knowledge and perception of under-utilized and future vaccines were however low. There is, therefore, need for more training and retraining of health care workers on the vaccines.

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Evaluation of the Skin Infections and Conditions among Students of Gomal Medical College Pakistan

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i33b31814 ◽

2021 ◽

pp. 218-222

Author(s):

Shumaila Parveen ◽

Yaser M. Alahmadi ◽

Faryal Adnan ◽

Eshawa Darr ◽

Ali Alalawi ◽

...

Keyword(s):

Medical Students ◽

Observational Study ◽

Sample Size ◽

Total Sample ◽

Skin Infections ◽

Age Group ◽

Cross Sectional ◽

Total Sample Size ◽

Medical College ◽

Dermatological Disorders

Objective: The objective of the current study is to determine the pattern of dermatological disorders and to find out their connection with different socioeconomically factors among students of the Medical College. Methodology: The Cross sectional observational study was carried out for the period of three months .The research instrument used was the well developed questionnaire. Results: The questionnaire was administered among total 350 students and the most participant age group was the > 22 and that was about 47.4% of the total sample size the more skin complication seen was the acne that was about 59.7%, in addition to this dandruff contributed very heavily to the hair complexities which makes about 35.7% of the sample. Conclusion: Skin infections especially the cosmetic are very common among the Medical students.

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