scholarly journals Analisis Prioritas Tumbuhan Obat Berpotensi untuk Gangguan Mental Emosional dengan Metode Weighted Product (WP): Data Riset Tumbuhan Obat dan Jamu 2012, 2015, dan 2017

2019 ◽  
Vol 29 (3) ◽  
Author(s):  
Lusi Kristiana ◽  
Zainul Khaqiqi Nantabah ◽  
Herti Maryani
Keyword(s):  
Mental Disorders ◽  
Medicinal Plants ◽  
Emotional Disorders ◽  
Moringa Oleifera ◽  
Cocos Nucifera ◽  
Mimosa Pudica ◽  
Caesalpinia Sappan ◽  
Sesbania Grandiflora ◽  
Ocimum Tenuiflorum ◽  
Citrus Aurantiifolia

Abstract The 2018 Basic Health Research (Riskesdas) shows that the proportion of mental emotional disorders has increased compared to Risksesdas 2013 (9.8% from 6%), so that it has the potential to become a mental disorder that needs complex handling. The use of basic medicines for mental disorders in primary health care is limited due to the lack of competent and authorized health worker, besides the availability of medicines is very low. Research on Medicinal Plans and Herbs/Riset Tanaman Obat dan Jamu (Ristoja) has been carried out since 2012 and has resulted in successfully identifying more than 4,000 species of medicinal plants. One of them is a medicinal plant that is empirically used to overcome mental emotional disorders. Ristoja is an ethnomedicine study that needs further investigation. The research aims to prioritize/rank potential of medicinal plants for mental emotional disorders. The study analyzed secondary data of Ristoja in 2012, 2015, and 2017. Data were selected using the Weighted Product (WP) method to assess the priority of medicinal plants to be carried out in the next stage of research. Subsequent analysis of the WP method is used to determine the peringkat of medicinal plants. The results of the analysis show that of the 22 plants that caried out a literature search, there were only 9 medicinal plants that had the potential for mental emotional disorders, and were a priority for research. These plants are 1) Moringa oleifera (Kelor); 2) Sesbania grandiflora (Turi); 3) Spondias mombin (Yellow mombin); 4) Mimosa pudica (Putri malu); 5) Ocimum tenuiflorum (Lampes); 6) Basilicum polystachyon (Sangket); 7) Cocos nucifera (Kelapa); 8) Citrus aurantiifolia (Jeruk limau); 9) Caesalpinia sappan (Secang). These plants mostly work to suppress the central nervous system. Plants that have entered piority for mental disorders, can be performed pharmacologically and acute toxicity tests, in accordance with the stages of the development of traditional medicine in Indonesia. Abstrak Data Riset Kesehatan Dasar (Riskesdas) tahun 2018 menunjukkan proporsi gangguan mental emosional mengalami peningkatan dibanding Riskesdas 2013 (9,8% dari 6%), sehingga berpotensi menjadi gangguan jiwa yang perlu penanganan kompleks. Penggunaan obat dasar gangguan mental di pelayanan kesehatan primer dibatasi karena kurangnya petugas kesehatan yang kompeten dan berwenang, selain itu ketersediaan obat sangat rendah. Riset Tanaman Obat dan Jamu (Ristoja) dilakukan sejak tahun 2012 dan telah berhasil mengidentifikasi lebih dari 4.000 spesies tumbuhan obat, salah satunya adalah tumbuhan untuk mengatasi gangguan mental emosional. Ristoja merupakan studi etnomedisin yang perlu diteliti lebih lanjut. Penelitian bertujuan untuk melakukan prioritas/ peringkat tumbuhan obat berpotensi untuk gangguan mental emosional. Penelitian menganalisis data sekunder Ristoja tahun 2012, 2015, dan 2017. Data diseleksi menggunakan metode Weighted Product (WP) untuk menilai prioritas tumbuhan obat yang akan dilakukan penelitian pada tahap berikutnya. Analisis selanjutnya metode WP digunakan untuk menentukan peringkat tumbuhan obat. Hasil analisis menunjukkan bahwa dari 22 tumbuhan yang dilakukan penelusuran literatur, hanya ada 9 tumbuhan yang berpotensi untuk gangguan mental emosional, serta menjadi prioritas untuk dilakukan penelitian. Tumbuhan tersebut adalah:1) Moringa oleifera (Kelor); 2) Sesbania grandiflora (Turi); 3) Spondias mombin (Yellow mombin); 4) Mimosa pudica (Putri malu); 5) Ocimum tenuiflorum (Lampes); 6) Basilicum polystachyon (Sangket); 7) Cocos nucifera (Kelapa); 8) Citrus aurantiifolia (Jeruk limau); 9) Caesalpinia sappan (Secang). Tumbuhan tersebut sebagian besar bekerja menekan sistem saraf pusat. Tumbuhan yang sudah masuk prioritas untuk gangguan mental, dapat dilakukan uji farmakologi dan toksisitas akut, sesuai dengan tahapan pengembangan obat tradisional di Indonesia.

scholarly journals ​Nutritional Evaluation of Predominant Tree Fodders and Shrubs of Southern Kerala as a Quality Livestock Feed

2021 ◽  
Author(s):  
P. Mubeena ◽  
Usha C. Thomas ◽  
Deepa Surendran
Keyword(s):  
Crude Protein ◽  
Moringa Oleifera ◽  
Cocos Nucifera ◽  
Mangifera Indica ◽  
Neutral Detergent Fiber ◽  
Crude Fiber ◽  
Fodder Trees ◽  
Mean Values ◽  
Livestock Feed ◽  
Sesbania Grandiflora

Background: India ranks first in global livestock production and it is an important subsidiary enterprise that support more than 75 per cent of the rural community. But fodder production is not well practiced in our country and animals generally consume naturally grown grasses and shrubs which are of low quality in terms of protein and available energy. Hence, there is an urgent need to look for new fodder resources that are sustainable in nature and cover our fodder deficit. Keeping the above in view, the present study has been proposed to evaluate the predominant tree fodders and shrubs of Southern Kerala as a quality livestock feed. Methods: The study was conducted in College of Agriculture, Vellayani, Thiruvananthapuram during January-September, 2020 to assess the nutritional value of predominant tree fodders and shrubs in Southern Kerala as a quality feed for cattle. Ten different fodder trees and shrubs that locally fed to the cattle viz., Agathi (Sesbania grandiflora), erythrina (Erythrina indica), Drumstick (Moringa oleifera), Coconut (Cocos nucifera), Glyricidia (Glyricidia maculate), Matti (Terminalia elliptica), Subabul (Leucaena leucocephala), Cassava (Manihot esculenta), Banana (Musa acuminate) and Mango (Mangifera indica) were selected and analysed for proximate composition, crude fiber and mineral status. Result: The result revealed that mean values for dry matter, crude protein, crude fiber, ether extract and total ash in tree fodders were 37.07±4.02, 18.52±1.72, 18.56±2.07, 4.68±0.51, 8.72±0.66, respectively. The study also proved that Sesbania grandiflora (Agathi) is nutritionally superior to other tree fodders with high crude protein (25.24%) and lower crude fiber (8.43%) content. The Neutral Detergent Fiber content of fodder tree leaves varied from 17.34- 65.32 per cent and that of Acid Detergent Fiber from 11.10-48.69 per cent. Phosphorus and potassium status of top feeds comes under the range of 0.26-0.93 per cent and 1.0-2.7 per cent respectively. However the highest amount of Calcium as well as magnesium was found in Moringa oleifera (2.75 and 0.60 per cent respectively).

scholarly journals In Silico Approach of Potential Phytochemical Inhibitor from Moringa oleifera, Cocos nucifera, Allium cepa, Psidium guajava, and Eucalyptus globulus for the treatment of COVID-19 by Molecular Docking

2020 ◽  
Author(s):  
Ika Nur Fitriani ◽  
Wiji Utami ◽  
Adi Tiara Zikri ◽  
Pugoh Santoso
Keyword(s):  
Molecular Docking ◽  
Medicinal Plants ◽  
Oleanolic Acid ◽  
Allium Cepa ◽  
Bioactive Compounds ◽  
In Silico ◽  
Eucalyptus Globulus ◽  
Moringa Oleifera ◽  
Cocos Nucifera ◽  
Psidium Guajava

Abstract Background Coronavirus disease 2019 (COVID-19) is caused by infection with severe acute respiratory syndrome coronavirus 2. COVID-19 has devastating effects on people in all countries and getting worse. We aim to investigate an in-silico docking analysis of phytochemical compounds from medicinal plants that used to combat inhibition of the COVID-19 pathway. There are several phytochemicals in medicinal plants, however, the mechanism of bioactive compounds remains unclear. These results are obtained from in silico research provide further information to support the inhibition of several phytochemicals. Methods Molecular docking used to determine the best potential COVID-19 M pro inhibitor from several bioactive compounds in Moringa oleifera, Allium cepa, Cocos nucifera, Psidium guajava, and Eucalyptus globulus. Molecular docking was conducted and scored by comparison with standard drugs remdesivir. ADME properties of selected ligands were evaluated using the Lipinski Rule. The interaction mechanism of the most recommended compound predicted using the STITCH database. Results There was no recommended compound in Moringa oleifera as a potential inhibitor for COVID-19. Oleanolic acid in Allium cepa, α-tocotrienol in Cocos nucifera, asiatic acid in Psidium guajava and culinoside in Eucalyptus globulus were the most recommended compound in each medicinal plant. Oleanolic acid was reported to exhibit anti-COVID-19 activity with binding energy was − 9.20 kcal/mol. This score was better than remdesivir as standard drug. Oleanolic acid interacted through the hydrogen bond with HIS41, THR25, CYS44, GLU166. Oleanolic acid binding with CASP-3, CASP-9, and XIAP signaling pathway. Conclusions Oleanolic acid in Allium cepa found as a potential inhibitor of COVID-19 M-pro that should be examined in future studies. These results suggest that oleanolic acid may be useful in COVID-19 treatment.

scholarly journals DADOS DA OBTENÇÃO DO PÓLEN POR OPERÁRIAS DE Apis mellifera NO MUNICÍPIO DE JI-PARANÁ (RO), BRASIL

1993 ◽  
Vol 23 (1) ◽  
pp. 59-76 ◽  
Author(s):  
Antonio Carlos MARQUES-SOUZA ◽  
Maria Lúcia ABSY ◽  
Paulo Afonso Amato CONDÉ ◽  
Hugo de Alencar COELHO
Keyword(s):  
Apis Mellifera ◽  
Cocos Nucifera ◽  
Mimosa Pudica

Foram analisados os pólen corbiculares de operárias de Apis melliferadurante o período de dois anos, no Município de Ji-Parana(RO). Constatou-se que dos 126 tipos polínicos coletados, apenas uma pequena parte (12,0%) foram intensamente explorados pelas africanizadas, destacando-se entre eles: Cecropiasp., Orbignya martiana,Poaceae tipo, Cosmos caudaíus, Cocos nucifera, Cynometrasp., Mimosa pudica, Cissussp., etc. que tiveram seus pólen coletados em mais de dez meses. Observou-se que a coleta de pólen pelas Apis,na Amazônia, não está relacionada com as mudanças climáticas e sim com a época de floração das fontes. Fevereiro de 1989 foi o mês onde as operárias mais diversificaram, coletando 41 tipos de plantas. Os meses de março, novembro de 1988 e janeiro de 1990 foram os meses que apresentaram a menor diversificação num total de onze espécies de plantas coletadas pelas operárias.

scholarly journals Specific mental disorder screening compilation may detect general mental disorders

2018 ◽  
Vol 13 (40) ◽  
pp. 1-13
Author(s):  
Lívia Maria Bolsoni ◽  
Leonardo Moscovici ◽  
João Mazzoncini De Azevedo Marques ◽  
Antonio Waldo Zuardi
Keyword(s):  
General Population ◽  
Mental Disorders ◽  
Emotional Disorders ◽  
Intraclass Correlation ◽  
Area Under The Curve ◽  
Roc Curves ◽  
Screening Tools ◽  
Patient Health ◽  
Two Phases ◽  
Specific Disorders

Objective: To evaluate whether a short compilation of screening tools for specific disorders could identify Mental or Emotional Disorders (MEDs) in the general population. Methods: We selected validated screening tools for the most prevalent MEDs. In order to be selected, these tools should maintain the psychometric properties of the complete instrument with a reduced number of items. These instruments were: Patient Health Questionnaire-2 (PHQ-2), Generalized Anxiety Disorder Scale-2 (GAD-2), item 3 of the Alcohol Use Disorders Identification Test (AUDIT), and three items on the Adolescent Psychotic-Like Symptom Screener (APSS-3). We called this compilation of screening tools Mini Screening for Mental Disorders (Mini-SMD). The study was divided in two phases. Firstly, 545 subjects were interviewed with the Mini-SMD and COOP/WONCA-Feelings at their residences. Subsequently, subjects who had agreed to participate (230) were reinterviewed with Mini-SMD, COOP/WONCA-Feelings and MINI interview. Test-retest reliability was calculated by Intraclass Correlation Coefficient (ICC). Receiver operating characteristic (ROC) curves were generated for the analysis of discriminative validity. Concurrent validity was calculated by analyzing the correlation between Mini-SMD and COOP/WONCA-Feelings. Results: The joint administration of screening tools for specific disorders showed sensitivities that ranged from 0.76 to 0.88 and specificities from 0.67 to 0.85. The ICC value for the total score of Mini-SMD was 0.78. The area under the curve was 0.84, with a sensitivity of 0.74 and specificity of 0.76 (for a cutoff ≥ 4). Conclusion: This study showed that a short compilation of screening tools for specific disorders can detect MEDs in general population.

scholarly journals Assessment of Growth Characteristics of Medicinal Plants Ocimum tenuiflorum L. and Plectranthus amboinicus (Lour.) Spreng. Under Shade Net and Open Conditions

2020 ◽  
pp. 1-8
Author(s):  
J. Ambujavalli ◽  
K. Santhiya ◽  
K. Rohini ◽  
V. Kumaresan
Keyword(s):  
Medicinal Plants ◽  
Leaf Area ◽  
Plant Height ◽  
Growth Characteristics ◽  
Similar Type ◽  
Potted Plants ◽  
Ocimum Tenuiflorum ◽  
Number Of Leaves ◽  
Plectranthus Amboinicus ◽  
Microclimate Conditions

Aim: To study the effect of shade net on the growth characteristics of two medicinal plants viz., Tulsi and Indian Borage in terms of plant height, number of leaves, leaf area and flowering in relation to open condition. Place and Duration of Study: Lawspet, Puducherry, India between June 2018 and October 2018. Methodology: Tulsi and Indian Borage plants were grown in similar type of soil. The potted plants were kept in open, 35% and 75% shade net conditions and studied for 3 months. The plant height, number of leaves, and leaf area were measured including number of inflorescence branches for Tulsi. Results: The average air temperature was lower under shade net. Relative humidity was more in shade net conditions with maximum in 75% shade and least in open conditions. The number of leaves of Tulsi and Indian Borage recorded was maximum when grown under 35% shade and least in open conditions. Plant height was maximum in 75% shade for Tulsi and 35% shade in Indian Borage and least in open conditions on both the cases. Leaf area was maximum for both Tulsi and Indian Borage in 75% shade. Conclusion: Growth of the two medicinal plants was influenced by the microclimate conditions. The present study shows that the medicinal plants can be grown in shade net conditions to increase the yield of medicinally useful parts.

scholarly journals Correlation between BMI and ADLs with Mental Emotional Disorder among Elderly

2015 ◽  
Vol 3 (1) ◽  
pp. 1
Author(s):  
Nabilah Qonitah ◽  
Muhammad Atoillah Isfandiari
Keyword(s):  
Body Mass Index ◽  
Mental Disorders ◽  
Emotional Disorders ◽  
Body Mass ◽  
Elderly Care ◽  
The Elderly ◽  
Emotional Disorder ◽  
The Body ◽  
Body Function ◽  
Physical Independence

The increasing of life expectancy led to a growing number of elderly. There are many thing that occurs caused by aging process, one of them is decreases of body function. Decreasing body function can cause variety of health problems. The problem that may occurs are malnutrition, chronic disease, and lack of independence in performing daily activities. All of them are risk factor of mental emotional disorder. This study was conducted to determined the relationship between mental emotional disorders in the Elderly Care Unit Jombang in Kediri. This research was analytical study and used cross sectional. Dependent variable was mental emotional disorders. Independent variables were BMI, physical independence and characteristic. Interview was conducted to obtain information about variables in this study. Data analyzed by chi square and pearson correlation. The prevalence of mental disorders found in this study was 23,4%. Respondents who didn’t have physical independence were 4,3%. Respondents who had body mass index that wasn’t normal is 26,2%. The variables showed correlation only variable physical independence and mental emotional disorders (p = 0,008). While the body mass index and characteristic were not showed correlation with mental emotional disorders. The conclusion of this study was the elderly at risk for emotional suffering mental disorders. Physical independence associated with mental disorders in elderly emotional. So the need for more attention especially from the psychological to the elderly who do not have physical independence.Keywords: risk factors, BMI, physical independence, mental emotional disorder, elderly

scholarly journals Studi Etnobotani Masyarakat di Sekitar Kawasan Hutan Bedugul Bali

2019 ◽  
Vol 3 (2) ◽  
pp. 96-104
Author(s):  
I Dewa Putu Darma ◽  
Arief Priyadi ◽  
Rajif Iryadi
Keyword(s):  
Plant Species ◽  
Moringa Oleifera ◽  
Allium Sativum ◽  
Cocos Nucifera ◽  
Colocasia Esculenta ◽  
Conservation Education ◽  
Purposive Sampling ◽  
Musa Paradisiaca ◽  
Alstonia Scholaris ◽  
Environment Sustainability

The Ethnobotany study of society advantage knowing plant species that be used and this usefulness. This study purpose identification plant’s utilization and local wisdom in Bedugul area. This method is purposive sampling that based profession with interview to Dukun, Baten, housewife, Farmer, craftsmen and builder. Filed data were processed with quantitative to get the benefit index (BI) on 181 species. Top ten species have been the highest of BI such as: Musa paradisiaca (0.026718), Arenga pinnata (0.022901), Artocarpus integer (0.015267), Cocos nucifera (0.015267), Colocasia esculenta (0.015267), Curcuma domestica (0.015267), Schizostachyum brachyckadum (0.015267), Moringa oleifera (0.01145), Aleurites moluccanus (0.01145) & Allium sativum (0.01145). Four of them have rare status i. e: Borassus flabellifer, Alstonia scholaris, Eeucresta horsfieldii & Saurauia bracteosa. Bali culture which has reserved with conservation education (Tumpek Wariga ceremony, Wana Kertih & Danau Kertih) makes the environment sustainability.  

scholarly journals A review of medicinal plants that modulate nitric oxide activity

2012 ◽  
Vol 2 (1) ◽  
pp. 6
Author(s):  
Jillian Borchard ◽  
Lily Mazzarella ◽  
Kevin Spelman
Keyword(s):  
Nitric Oxide ◽  
Medicinal Plants ◽  
Plant Extracts ◽  
Cocos Nucifera ◽  
Herbal Medicines ◽  
Echinacea Purpurea ◽  
Tinospora Cordifolia ◽  
Nitric Oxide Signaling ◽  
Evolvulus Alsinoides ◽  
Sida Cordifolia

Modulation of nitric oxide (NO) may offer novel approaches in the treatment of a variety of diseases, such as Alzheimer’s, cardiovascular disease, and diabetes. A strategy in the modulation of NO expression may be through the use of herbal medicines. We surveyed medicinal plant research that utilized multicomponent extracts similar to what is used in clinical phytotherapy or in commerce, for demonstrated effects on NO activity. SciFinder Scholar, Pubmed, Web of Science, and BIOSIS were searched to identify human, animal, <em>in vivo</em>, <em>ex vivo </em>or <em>in vitro</em> research on botanical medicines, in whole or standardized form, that act on nitric oxide activity. iNOS was the most frequently investigated enzyme system and this system was up-regulated by many plant extracts, including, <em>Chicorium intybus, Cocos nucifera, Echinacea purpurea, Euonymus alatus, Ixeris dentate, Oldenlandia diffusa, Rhinacanthus nasutus, and Sida cordifolia. Many plant extracts down-regulated iNOS, including Centella asiatica, Dichroa Febrifuga, Echinacea purpurea, Evolvulus alsinoides, Fagonia cretica, Ginkgo biloba, Mollugo verticillata, Lactuca indica, Lithospermum erythrorhizon, Pueraria thunbergiana, and Taraxacum officinale</em>. The eNOS system was stimulated by <em>Eucommia ulmoides, Sida cordifolia</em>, and <em>Thymus pulegioides while Fagonia cretica, Rubia cordifolia</em> and <em>Tinospora cordifolia </em>down-regulated nNOS. Given the activity demonstrated by many of these herbal medicines, the increasing awareness of the effects of nitric oxide on a wide variety of disease processes and the growing incidence of these conditions in the population, further study of medicinal plants on nitric oxide signaling may lead to novel therapies and further insight into human physiology.

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