scholarly journals EFEKTIVITAS BUBUK BIJI PEPAYA (Carica Papaya Linnaeaus) SEBAGAI LARVASIDA ALAMI TERHADAP KEMATIAN LARVA AEDES AEGYPTY TAHUN 2015

2017 ◽  
Vol 18 (01) ◽  
pp. 12-18
Author(s):  
Iwan Iskandar ◽  
Hevi Horiza ◽  
Nanang Fauzi
Keyword(s):  
Data Analysis ◽  
Aedes Aegypti ◽  
Significant Influence ◽  
Carica Papaya ◽  
Control Group ◽  
Total Percentage ◽  
Group Research ◽  
Papaya Seeds ◽  
One Way Anova ◽  
True Experiment

Papaya seeds are excellent to be used as a repellent larvae of Aedes aegypti because of the toxins contained in papaya seeds called alkaloid karpaina. The research objective was to determine the effectiveness of papaya seeds powder as Aedes aegypti larvicides. This type of research is True Experiment with Posttest Only Control Group research design, using five treatments (4 grams, 8 grams, 12 grams, 16 grams and 20 grams) and one control. Objects that are used as many as 600 larvaes of Aedes aegypti. If the papaya seeds powder in a simple processsuch as drying and grinding. Each treatment contains 50 larvaes and by doing 2 times repeatedly. The results of data analysis on the number of dead larvaes at a dose trending dead at the lowest possible total percentage of 22% at a dose of 4 grams and the highest percentage of 97% at a dose of 20 grams. The analysis result of one-way ANOVA for the number of differences in the number of dead larvaes, with the value obtained sig. = 0.000, so that ? <? (0.05) means that there is a significant influence on differences in doses of papaya seeds powder solution used against the death of Aedes aegypti larvaes. The control of Aedes aegypti larvaes using papaya seeds powder can be done by puttingthe powder of papaya seeds as much as 20 grams per 10 liters of water for 24 hours of treatment.

scholarly journals Fermentasi Air Kelapa Muda sebagai Atraktan Nyamuk Aedes aegypti

2018 ◽  
Vol 16 (1) ◽  
Author(s):  
Devinta Lala ◽  
Suprijandani . ◽  
Nur Haidah
Keyword(s):  
Aedes Aegypti ◽  
Water Concentration ◽  
Statistical Test ◽  
Coconut Water ◽  
Control Group ◽  
Mosquito Vectors ◽  
Group Research ◽  
Significant Difference ◽  
Water Trapping ◽  
True Experiment

The case of dengue fever caused by Aedes aegypti female mosquitoes is still a problem in Indonesia because the case tends to increase every year. The purpose of study on the fermentation of young coconut water as a mosquito attractant is to determine whether there is any difference in the number of mosquitoes trapped by the fermentation of young coconut water concentration variation. The type of research conducted was a True Experiment, with the design ofpost test only control group. Research method was using trapping bottle provided with attractant with a concentration of 0% (control), 15%, 25%, and 35%. Location of research was done in Laboratorium Entomologi Kesehatan Lingkungan Politeknik Kesehatan Kemenkes RI Surabaya. Data were analyzed using Kruskal Wallis statistical test and advanced test of Mann Whitney. The result of Kruskall Wallis statistic test showed that there is significant difference (p <0,05) between control group and treatment group of variation of coconut water fermentation concentration to the number of trapped mosquitoes. Advanced tests of Mann Whitney showed that three concentration treatments (15%, 25%, and 35%) had the same potential because there is no significant difference. Higher mean rank values at the 15% coconut water fermentation concentration is because it has the ability of trapping mosquitos more compared to other concentration (25%, and 35%). Young coconut water fermentation has potential as an Aedes aegypti mosquito attractant. The use of young coconut water fermentation attractant is a method of controlling mosquito vectors that is environmentally friendly and inexpensive to use. Keywords : Aedes, Attractant, Fermented Young Coconut Water, Trapping

scholarly journals Status Kerentanan Aedes Aegypti Vektor Demam Berdarah Dengue di Kota Padang

2017 ◽  
Vol 6 (2) ◽  
pp. 440
Author(s):  
Kharisma Putra D ◽  
Hasmiwati Hasmiwati ◽  
Arni Amir
Keyword(s):  
Aedes Aegypti ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
One Way Anova

Salah satu upaya untuk mengurangi kasus DBD adalah dengan pengendalian vektor DBD dengan larvisida. Temephos merupakan salah satu insektisida yang telah digunakan lebih dari 30 tahun dan berfungsi mengendalikan larva vektor. Penggunaan temephos yang tidak sesuai aturan dapat menyebabkan penurunan kerentanan pada vektor DBD.  Tujuan penelitian ini  adalah untuk  menilai  status  kerentanan larva Aedes aegypti di tiga kecamatan di Kota Padang. Penelitian ini menggunakan post  test  only  with  control  group design. Telur diambil dan dipelihara di laboratorium hingga mencapai larva instar III/IV. Uji kerentanan untuk temephos dilakukan berdasarkan standar WHO. Hasil penelitian menunjukkan pada Kecamatan Kuranji, kematian larva pada konsentrasi 0,005 mg/L sebesar 10%, 0,01 mg/L sebesar 45%, 0,02 mg/L sebesar 86%, dan pada konsentrasi 0,03 mg/L sebesar 100%. Pada Kecamatan Koto Tangah, kematian larva pada konsentrasi 0,005 mg/L sebesar 24%, 0,01 mg/L sebesar 48%, 0,02 mg/L sebesar 99%, dan pada konsentrasi 0,03 mg/L sebesar 100%. Pada Kecamatan Padang Timur pada konsentrasi 0,005 mg/L didapatkan kematian larva sebesar 12%, pada 0,01 mg/L sebesar 43%, pada 0,02 mg/L sebesar 99%, dan pada 0,03 mg/L sebesar 100%. Hasil uji One way-Anova adalah bermakna dengan nilai p<0,05 pada ketiga kecamatan dan LC99 sedikit diatas 0,02 mg/L. Simpulan penelitian ini adalah status kerentanan Aedes aegypti terhadap temephos di tiga kecamatan berkisar antara rentan dan toleran, belum mencapai resisten sehingga temephos masih dapat digunakan dalam pengendalian vektor DBD.

Effect of Ethanolic Extract of Carica Papaya seeds in Drug-Induced Acute Nephrotoxicity

2021 ◽  
Vol 15 (11) ◽  
pp. 2951-2953
Author(s):  
Sameer Ahmed ◽  
Muhammad Tahir ◽  
Attiya Munir ◽  
Amtul Hafeez ◽  
Sher Afghan Khan ◽  
...  
Keyword(s):  
Carica Papaya ◽  
Ethanolic Extract ◽  
Control Group ◽  
Standard Diet ◽  
Serum Urea ◽  
Once Daily ◽  
Group Iii ◽  
Group I ◽  
Papaya Seeds ◽  
Group Ii

Background: Nephrotoxicity is characterized by raised serum urea and creatinine levels and kidneys being one of the primary organs of drug concentration and excretion are vulnerable to many widely used marketed drugs, including anti-cancer drugs, antibiotics, immunosuppressants, and radio contrast agents, are nephrotoxic. Aim: To determine the nephroprotective effect of ethanolic extract of Carica papaya seeds in Aminoglycoside induced acute nephrotoxicity. Study design: Quasi Experimental study. Methodology: Thirty Sprague Dawley rats were sub divided into 3 groups i.e., I, II and III with 10 rats in each group. Group II and III were administered Aminoglycoside drug; Gentamycin in 80 mg/kg) via intraperitoneal route once daily for 5 consecutive days to induce acute nephrotoxicity. At day 6, nephrotoxicity was confirmed by measuring serum urea and creatinine. Ethanolic extract of Carica papaya seeds (1000 mg/kg) was started once daily through oral route in group III for 5 consecutive days to see the nephroprotective effects of seed extract after causing acute kidney injury. All animals were given standard diet pellets manufactured at NIH. Results: Mean serum urea and creatinine for Group I (Control Group) at day 0 were 24.90 mg/dL ± 1.633 and .750 mg/dL ± .0619 respectively. Mean serum urea and creatinine for Group II (Disease Control Group) was 81.00 mg/dL ± 1.247 and 1.980mg/dL ± .0467 at day 6th. This suggested induction of nephrotoxicity by Gentamycin. Mean serum urea and creatinine for Group III (Ethanolic Extract Treated Group) at 11 day was 72.40mg/dL± .991 and 1.680 mg/dL± .0467 after 5 days treatment with ethanolic extract of Carica papaya seeds. Conclusion: We concluded that ethanolic extract of Carica papaya seeds has significant nephroprotective effects on Aminoglycoside induced acute nephrotoxicity in rats. Keywords: COVID-19, Vaccination, Awareness and Adverse Effects

scholarly journals UJI EFEKTIFITAS EKSTRAK BIJI KETUMBAR (Coriandrum sativum) SEBAGAI REPELLENT NYAMUK Aedes aegypti

2017 ◽  
Vol 15 (2) ◽  
Author(s):  
Nurul Jubaedah ◽  
Winarko . ◽  
Fitri Rohmalia
Keyword(s):  
Aedes Aegypti ◽  
Aedes Albopictus ◽  
Coriandrum Sativum ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
One Way Anova ◽  
Culex Sp

Penyakit Demam Berdarah Dengue (DBD) di Surabaya semakin meningkat setiap tahunnya. Salah satu pencegahan untuk menurunkan kasus penyakit Demam Berdarah Dengue (DBD) dengan menggunakan repellent. Repellent dapat dibuat dari bahan alami yaitu ketumbar (Coriandrum sativum)yang di ekstrak. Ketumbar (Coriandrum sativum) memiliki kandungan linalool yang terkenal sebagai bahan yang dapat mencegah nyamuk Aedes aegypti untuk menggigit. Kandungan linalool pada ketumbar (Coriandrum sativum) sebesar 60-70%. Tujuan penelitian ini yaitu untuk menganalisis efektifitas ekstrak biji ketumbar sebagai repellent terhadap nyamuk Aedes aegypti.            Jenis penelitian ini eksperimen murni dengan desain penelitian Rancangan Eksperimen Sederhana (posttest only with control group design). Kelompok perlakuan diberi perlakuan dengan dosis bertingkat. Terdapat 5 perlakuan repellent dari ekstrak ketumbar (Coriandrum sativum) terhadap nyamuk Aedes aegypti yaitu 0%, 45%, 50%, 55%, dan 60% dengan replikasi sebanyak 4 kali. Kondisi yang dikendalikan yaitu suhu, kelembaban dan karakteristik nyamuk. Teknik pengumpulan data diperoleh dari hasil observasi eksperimental dan wawancara. Data yang diperoleh selanjutnya dianalisis secara analitik menggunakan uji One way ANOVA dan menggunakan analisis probit.            Nyamuk Aedes aegypti yang kontak paling sedikit yaitu 1 ekor pada konsentrasi 60%. Suhu dan kelembaban ruang penelitian homogen. Tidak ada perbedaan jumlah nyamuk kontak pada  konsentrasi ekstrak biji ketumbar 0%, 45%, 50%, 55%, dan 60%. Konsentrasi yang paling efektif dari hasil probit yaitu konsentrasi 60% dengan daya tolak sebesar 98% dan daya proteksi lama waktu yang memenuhi standar WHO selama 2 jam. Saran untuk peneliti selanjutnya agar meningkatkan konsentrasi untuk mendapatkan daya proteksi 100%. Penelitian terhadap jenis nyamuk yang lainnya seperti nyamuk Culex sp, Anopheles sp, Mansonia sp dan Aedes albopictus. Membuat repellent ekstrak biji ketumbar dalam bentuk krim atau gel.           Kata kunci : ekstrak ketumbar, nyamuk Aedes aegypti, dan repellent

scholarly journals TEST OF COPPER WIRE DOSE EFFECTIVENESS ON LARVAL MORTALITY OF Aedes Aegypti MOSQUITO IN 2015

2015 ◽  
Vol 13 (2) ◽  
Author(s):  
Pristiana Rahayu ◽  
Winarko . ◽  
Siti Surasri
Keyword(s):  
Data Analysis ◽  
Aedes Aegypti ◽  
Experimental Research ◽  
Copper Wire ◽  
Larval Mortality ◽  
Effective Control ◽  
Control Group ◽  
Success Criteria ◽  
Media Source ◽  
Post Test

Control of Aedes aegypti mosquito population still leaves problem that needs to be addressed. Theuse of copper wire as an alternative of  larvicide has been studied yet it has not shown asatisfactory result. This is study pure experimental research using research design post test only control group designwith larvae of Aedes aegypti third instar as samples. Methods of data analysis were descriptiveanalysis and analytical analysis.Experiment result shows that based on the success criteria for effective control and safe for health,this research has not found an effective dose of copper wire to kill larvae of Aedes aegyptimosquito that is safe for health for the percentage of larval mortality with concentration of 38.7%Cu was still below 2 ppm.It is recommended that governments and communities use and promote copper wire as analternative larvicide for vector eradication of dengue with predetermined limit of use that is safe forhealth. Further research can be also carried out with media source of water and variety of concentration.

scholarly journals The Effect of Consumer Attitude toward Functional Food on Package Attributes and Ingestion Intention; Focused on Garlic

2018 ◽  
Vol 7 (3.33) ◽  
pp. 8
Author(s):  
Hyun Kyoung Kim ◽  
Hyun Jeong Kim ◽  
Su Jong Cha
Keyword(s):  
Data Analysis ◽  
Prior Knowledge ◽  
Significant Influence ◽  
Functional Food ◽  
Food Packaging ◽  
Consumer Attitude ◽  
One Way Anova ◽  
Selection Of

The purpose of this study was to investigate the effect of prior knowledge and preference of garlic on the ingestion intention and selecting package attributes of garlic functional food. Surveys were conducted to verify the purpose of the study. One-way ANOVA was performed for data analysis; the following conclusions were reached.First, the prior knowledge and preference of garlic have a significant impact on the intention to ingest garlic functional food. Second, the prior knowledge and preference of garlic have a significant impact on the attitude toward package properties of garlic functional food.However, it was confirmed that the preference for garlic was a more significant influence on the selection of garlic functional food and garlic food packaging than the prior knowledge on the benefit of garlic. So this study casts significant implications for the marketing of functional food with strong flavors such as garlic.  

Efek Pemberian Ekstrak Biji dan Ekstrak Daun Pepaya (Carica papaya Linn) terhadap Kadar Kolesterol Total dan Trigliserida Tikus Putuh Jantan Galur Wistar (Rattus norvegicus) yang Diberi Diet Tinggi Lemak

2017 ◽  
Vol 15 (1) ◽  
Author(s):  
ESA PUTRI RIDHA YANTI
Keyword(s):  
Rattus Norvegicus ◽  
Random Sampling ◽  
Carica Papaya ◽  
Simple Random Sampling ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Total Diet ◽  
Post Test ◽  
One Way Anova

<p align="center"><strong>ABSTRAK</strong></p><p><strong>Latar Belakang.  </strong>Di Indonesia angka kejadian penyakit kardiovaskuler menunjukkan peningkatan dari tahun ke tahun dan salah satu faktor resikonya adalah hiperlipidemia terutama hiperkolesterolemia. Penelitian menyatakan bahwa kandungan biji pepaya yang berpotensi menyebabkan efek hiperkolesterolemik adalah flavonoid, saponin, dan tanin. Pada skrining fitokimia untuk daun pepaya menunjukkan adanya alkaloid, flavonoid, tanin, dan glukosida. Penelitian ini bertujuan untuk mengetahui efek pemberian ekstrak biji pepaya dan ekstrak daun pepaya terhadap kadar kolesterol total dan trigliserida tikus putih jantan galur wistar yang diberi diet tinggi lemak.</p><p><strong>Metode.</strong>  Penelitian ini menggunakan rancangan Post Test Only Control Group design. Teknik pengambilan sampel dengan metode simple random sampling. Sampel penelitian yang digunakan adalah 32 ekor tikus Rattus norvegicus putih jantan yang dibagi menjadi 4 kelompok, yaitu kelompok control negative, kelompok hewan coba yang diberi diet tinggi lemak, kelompok hewan coba yang diberi diet tinggi lemak dan ekstrak daun papaya, dan kelompok hewan coba yang diberi diet tinggi lemak dan ekstrak biji papaya. Penelitian dilakukan di Laboratorium Biokimia Universitas Hang Tuah Surabaya.</p><p><strong>Hasil. </strong> Hasil analisis Kruskal – Wallis dan One Way Anova test menunjukkan penurunan kadar trigliserida dan kolesterol total yang tidak signifikan pada kelompok yang diberi diet ekstrak daun pepaya dan kelompok yang diberi ekstrak biji pepaya (p &gt;0,05).</p><p><strong>Kesimpulan.</strong>  Pemberian ekstrak biji papaya dan ekstrak daun tidak menurunkan kadar kolesterol total dan trigliserida.</p><p><strong>Kata Kunci :</strong> Trigliserida, Kolesterol Total, Diet Tinggi Lemak, Ekstrak Biji Pepaya, Ekstrak Daun Pepaya.</p>

scholarly journals PENGARUH METODE PENGERINGAN TERHADAP KADAR FLAVONOID DAUN SESEWANUA (Clerodendron squamatum Vahl.)

PHARMACON ◽  
2019 ◽  
Vol 8 (3) ◽  
pp. 748
Author(s):  
Jeremy J. Hohakay ◽  
Julius Pontoh ◽  
Adithya Yudistira
Keyword(s):  
Data Analysis ◽  
Significant Influence ◽  
Drying Methods ◽  
Drying Method ◽  
Flavonoid Content ◽  
One Way Anova

ABSTRACTGlorybower (Clerodendron squamatum Vahl.) have been empirically used to treat fevers, fractures, and swelling-reduction. Glorybower leaves contain flavonoids and alkaloids which can be potential as antioxidants. The purpose of this study was to determine the effect of the drying method in determining the levels of flavonoids in glorybower leaves (Clerodendron squamatum Vahl.). Extraction of leaves using the maceration method. Determination of flavonoid content was using UV-Vis Spectrophotometer method with the principle of AlCl3. From the results obtained, the samples that had the highest to lowest flavonoid content were fresh samples which were 12 mg/ g extracts, 40oC samples were 7,8 mg/ g extract, air-dried samples were 7,2 mg / g extracts and 60oC samples which were 6,2 mg/ g extracts. Data analysis using one-way ANOVA method and the results obtained are Fcount = 9,709661639 and Ftable = 4,066180551. From these results, it can be concluded that Fcount is greater than Ftable. So that it can be seen that there is a significant influence between the existing drying methods. Keywords: Clerodendron squamatum Vahl, Drying Method, Extraction, Flavonoids, UV  Vis Spectrophotometer ABSTRAKSesewanua (Clerodendron squamatum Vahl.) secara empiris telah digunakan untuk mengobati demam, patah tulang, dan penurun bengkak. Daun sesewanua mengandung flavonoid dan alkaloid yang dapat berpotensi sebagai antioksidan. Tujuan penelitian ini adalah untuk mengetahui pengaruh metode pengeringan dalam penetapan kadar flavonoid pada daun sesewanua (Clerodendron squamatum Vahl.). Ekstraksi daun sesewanua menggunakan metode maserasi. Penetapan kadar flavonoid menggunakan metode Spektrofotometer UV-Vis dengan prinsip AlCl3. Dari hasil yang didapatkan, sampel yang memiliki kadar flavonoid tertinggi sampai terendah adalah sampel segar yaitu 12 mg/g ekstrak, sampel 40oC yaitu 7,8 mg/g ekstrak, sampel keringanginkan yaitu 7,2 mg/g ekstrak, dan sampel 60oC yaitu 6,2 mg/g ekstrak. Analisis data menggunakan metode anova satu jalur dan didapatkan hasil yaitu F hitung= 9,709661639 serta F tabel =4,066180551. Dari hasil tersebut, dapat ditarik kesimpulan bahwa F hitung lebih besar dari pada F tabel. Sehingga dapat dilihat bahwa terjadi pengaruh yang cukup signifikan antara metode pengeringan yang ada. Kata Kunci: Clerodendron squamatum Vahl., Metode Pengeringan, Ekstraksi, Flavonoid, Spektrofotometer UV-Vis

scholarly journals Penggunaan Larutan Pepaya (Carica papaya) sebagai Larvasida Nyamuk Aedes aegypty

2019 ◽  
Vol 7 (2) ◽  
pp. 59
Author(s):  
Restu Prastiwi ◽  
Anita Dewi Moelyaningrum ◽  
Prehatin T. N
Keyword(s):  
Experimental Study ◽  
Aedes Aegypti ◽  
Carica Papaya ◽  
Larval Growth ◽  
Hemorrhagic Fever ◽  
The Body ◽  
The Other ◽  
Control Group ◽  
Significant Difference ◽  
The Impact

<p><em>Aedes aegypti mosquito is a type of mosquito that can carry dengue virus that causes dengue fever. This mosquito has the potential to transmit dengue hemorrhagic fever (DHF). DHF is a disease characterized by sudden fever, bleeding both on the skin and in other parts of the body and can cause shock and death. So in order to reduce the impact of the disease, there are several ways that must be taken. One way of controlling that is done to reduce the population of aedes aegypti mosquitoes is by reducing larval growth by using a solution of papaya leaves as larvacide. Papaya leaves contain tannins of 0.12%. So it is possible to kill larvae. The purpose of this study was to analyze the differences in the average mortality of untreated instar 1 aedes aegypti larvae and treated with a solution of distilled papaya leaves, amounting to 0ml / 100ml (X0), 1ml / 100ml (X1), 2ml / 100ml (2) , 4ml / 100m (X3) with observations every 6 hours for 24 hours. This study is a true experimental study with the presentation of the data analyzed using the kruskal wallis test on spss. The results showed that there were differences between the control group and the treatment group (p &lt;0.05). The most significant difference occurred in the 4ml / 100ml (X3) group which had the highest mortality than the other groups. So the higher the concentration and the longer the duration of exposure, the higher the mortality rate in the larvae. </em></p>

scholarly journals UJI DAYA PROTEKSI EKSTRAK DAUN PEPAYA (Carica papaya L) DALAM SEDIAAN LOTION DENGAN BASIS PEG400 SEBAGAI REPELLENT TERHADAP AEDES AEGYPTI

2017 ◽  
Vol 4 (3) ◽  
pp. 318
Author(s):  
Angger Luhung Nur Fadilah ◽  
Widya Hary Cahyati ◽  
Rudatin Windraswara
Keyword(s):  
Aedes Aegypti ◽  
Carica Papaya ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
Post Hoc

Demam Berdarah Dengue (DBD) ditularkan melalui gigitan nyamuk Aedes betina. Salah satu upaya pengendalian vektor yang populer di masyarakat yaitu menggunakan insektisida kimiawi akan tetapi menyebabkan resistensi pada nyamuk dan keracunan pada manusia. Upaya pengendalian dapat berupa insektisida alami yang terbuat dari tumbuhan, salah satunya yaitu daun pepaya (Carica papaya L). Tujuan dari penelitian ini adalah untuk mengetahui daya proteksi lotion ekstrak daun pepaya untuk menolak Aedes aegypti. Jenis penelitian ini adalah eskperimen murni dengan rancangan penelitian post test only control group design. Populasi penelitian adalah telur nyamuk Aedes aegypti yang dikembangbiakkan menjadi nyamuk, sampel 50 ekor nyamuk Aedes aegypti umur 2-5 hari untuk setiap kelompok perlakuan dengan 4 kali pengulangan, sehingga total nyamuk yang dibutuhkan 1.400 nyamuk Aedes aegypti karena jumlah perlakuan 7 kelompok. Data dianalisis menggunakan uji Anova dan Post Hoc. Hasil penelitian ini menunjukkan terdapat perbedaan persentase jumlah nyamuk yang hinggap pada berbagai konsentrasi lotion ekstrak daun pepaya dengan nilai signifikansi p=0,001 (p

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