REGIONAL FEATURES OF DEATHS FROM CARDIOVASCULAR DISEASES IN THE CONTEXT OF REGIONAL PROGRAM TO REDUCE CARDIOVASCULAR MORTALITY

2021 ◽  
pp. 21-27
Author(s):  
Ermolaev D.O. ◽  
Ermolaeva Yu.N.
Keyword(s):  
Cardiovascular Diseases ◽  
Medical Care ◽  
Medical Information ◽  
Health Care Organizations ◽  
Circulatory System ◽  
Total Mortality ◽  
Cardiovascular Complications ◽  
Cerebrovascular Diseases ◽  
Federal State ◽  
Research Findings

The relevance is determined by the high proportion of diseases of the circulatory system in the structure of the total mortality of the population, as well as the potential modifiability of external factors of pathology. The aim of the research is to study the regional epidemiology of mortality from diseases of the circulatory system in the context of a regional program to reduce it. Materials and methods - аn analysis of the structure and dynamics of mortality rates from diseases of the circulatory system and the peculiarities of the organization of medical care for the population of the Astrakhan Region with cardiovascular diseases for the 7-year period from 2014 to 2020, based on the data of the Medical Information and Analytical Center and the Office of the Federal State Statistics Service for the Astrakhan Region, was carried out. Results and discussion - diseases of the circulatory system rank first in the structure of total mortality in the Astrakhan region, which accounted for about half (48%) of all deaths in 2020. During the study period, an increase in mortality from diseases of the circulatory system was established by 2.8% with a sharp increase of 17.6% in 2020 compared to 2019, which is associated with the spread of coronavirus infection. At the same time, the proportion of deaths outside the hospital was 65% in 2020. It’s indicates both the late seeking of medical care and the shortcomings of dispensary observation of the category of citizens with the maximum risk of developing cardiovascular complications. In the structure of mortality from diseases of the circulatory system, ischemic heart disease is steadily leading, with an increase of 5.8% over the reporting period. The second place is occupied by cerebrovascular diseases, which showed a slight decrease by 3.3%. In addition to the infectious threats associated with the spread of the coronavirus COVID-19, it is necessary to take into account such a stable phenomenon as the progressive aging of the population when predicting the mortality rate for the coming years. Conclusion. Research findings can be used to adjust activities to health care organizations for patients with cardiovascular diseases at the regional level.

scholarly journals Specialized traumatological and orthopedic care for children through public-private partnership programs in the Novosibirsk region

2016 ◽  
Vol 4 (1) ◽  
pp. 37-42
Author(s):  
Tamara A Mylnikova
Keyword(s):  
Medical Care ◽  
Medical Information ◽  
Public Private Partnership ◽  
Medical Information System ◽  
Federal State ◽  
Organizational Model ◽  
Private Partnership ◽  
Novosibirsk Region ◽  
Orthopedic Care ◽  
Research Institute

Aim: To evaluate the feasibility of an organizational model of specialized traumatological and orthopedic care for children using public–private partnership mechanisms in the Novosibirsk region.Material and Methods: Data from patients visiting the Federal State Novosibirsk Research Institute of Traumatology and Orthopedics between 2011 and 2015 were acquired from “Medassist,” the local medical information system. Data were subsequently analyzed to identify the relative extent of medical care provided.Results: This study included results from an organizational model of specialized traumatological and orthopedic care for children developed via public–private partnership mechanisms that have been implemented in the Novosibirsk region since 2011. A number of institutions were involved in this model of medical care for children with traumatological and orthopedic pathology, including the Federal State Novosibirsk Research Institute of Traumatology and Orthopedics, Clinic “NIITO” (a non-governmental medical organization), and various other primary health care organizations, including children’s polyclinics and hospital outpatient departments. This model allowed us to create a closed (full) cycle of provision for specialized traumatological and orthopedic care, from primary treatment to the completion of rehabilitation with dynamic supervision throughout. This was accomplished by combining various clinical stages, including the specialized clinic, hospital, rehabilitation organization, and outpatient clinic. The main areas of this model include timely and reliable detection; determination of treatment indicators; appropriate definition of treatment terms; and the provision of specialized medical care, including high technology input, rehabilitation, and dynamic monitoring.Conclusions: Implementation of an organizational model of specialized traumatological and orthopedic care for children in the Novosibirsk region using mechanisms associated with public–private partnerships has proved to be very positive. Application of the model allowed improvements in the availability of specialized traumatological and orthopedic care for children to ensure succession in the stages of medical care and to increase the number of cases entering rehabilitation. Therefore, this model demonstrates the viability of providing medical care to the population through the mechanisms of public–private partnership.

scholarly journals Years of potential life lost from cardiovascular diseases of the economically active Russian population in 2013-2019

2021 ◽  
Vol 26 (5) ◽  
pp. 4161
Author(s):  
E. V. Samorodskaya ◽  
V. Yu. Semenov
Keyword(s):  
Cardiovascular Diseases ◽  
Heart Defects ◽  
Absolute Number ◽  
Cerebrovascular Diseases ◽  
Russian Population ◽  
Annual Reports ◽  
Federal State ◽  
Active Population ◽  
Artery Disease ◽  
Rate Of Decline

Aim. To analyze the changes in years of potential life lost (YPLL) from cardiovascular diseases (CVDs) of the economically active Russian population in 2013-2019.Material and methods. YPLL was estimated according to the Global Burden of Disease reports at the age of 15-72 years for 2013-2019. The required data were obtained from the annual reports of Federal State Statistics Service. Nonstandardized YPLL was estimated using the following equation: YPLL= ƩDi x ai, where Di is the absolute number of deaths at age I, ai — years not lived. The calculation was carried out for all-cause mortality and separately for CVDs (coronary artery disease (CAD), myocardial infarction (MI), cerebrovascular diseases, bleeding and strokes, and other CVDs).Results. In 2013-2019, there is a decrease in YPLL from all causes, including CVDs. In 2013, YPLL amounted to 14,918,7 years per 100000 economically active population, while in 2019 — 12199,9 years; from CVDs — 4471,6 and 3748,1 years, respectively. YPLL from CAD decreased by 21,5%, from MI — by 23,9%, from bleeding and strokes — by 17%. The rate of YPLL decline in 2014 compared to 2013 was 0,9%. Further, the rate of decline increased, reaching a maximum of 7,6% in 2017 compared to 2016. The differences in YPLL from all causes and CVDs between men and women are almost threefold, as well as from MI and CAD — 4,4 and 3,8 times, respectively. The contribution of CVDs to YPLL from all causes amounted to a maximum of 30,8% in 2018. The contribution of CAD to YPLL from CVDs decreased from 48,0% in 2013 to 44,9% in 2019. The contribution of MI to YPLL from CVDs in men (in 2019, 8%) is less than the contribution of alcoholic and unspecified cardiomyopathy (13,6%), while in women — 5,6% and 11,4%, respectively. There are no data on deaths from heart defects.Conclusion. The change in the YPLL from specific CVD causes occurs unevenly (by year and sex). MI, deaths from which is one of the key parameters of targeted mortality reduction programs, has a smaller effect on the YPLL level than cardiomyopathy, including alcoholic. To reduce mortality and YPLL at the economically active age, it is necessary to correct target programs.

DYNAMICS OF THE INCIDENCE OF DISEASES OF THE CIRCULATORY SYSTEM AMONG ADULTS AND CHILDREN IN VORONEZH

2020 ◽  
pp. 40-44
Author(s):  
Berezhnova T.A. ◽  
Kolyagina N.M. ◽  
Klepikov O.V. ◽  
Kulintsova Ya.V.
Keyword(s):  
Cardiovascular Diseases ◽  
Health System ◽  
Medical Care ◽  
Adult Population ◽  
Circulatory System ◽  
The Past ◽  
City District ◽  
Leading Position ◽  
Adults And Children ◽  
Access To Medical Care

Relevance. Over the past decade and at the present time, diseases of the circulatory system continue to occupy a leading position. Despite the implementation of Federal and regional programs aimed at improving the level of cardiological care and reducing the mortality of adults and children, the assessment of the level and dynamics of diseases of the circulatory system remains an urgent task for the health system. Aim: to analyze the dynamics of the incidence of diseases of the circulatory system of adults and children in Voronezh. Material and methods. In order to allow territorial comparison of morbidity levels, relative indicators were calculated per 1000 population of the corresponding age (children, adults). The assessment of the level of morbidity was carried out by analyzing medical and statistical data on the population's access to medical care over a five-year period. Results. This study is devoted to the assessment of the incidence of diseases of the circulatory system, which was carried out by analyzing medical statistics on the population's access to medical care for five years. It was found that the average long-term level of cardiovascular diseases in the Voronezh city district is 24.79±1.40 cases per 1000 children under 14 years of age, and 403.14±21.36 cases per 1000 adults 18 years and older for the adult population. Over the past 5 years (2014-2018), there has been an increase in the incidence of both children and adults. Conclusion. Thus, knowledge of information about the morbidity of adults and children makes it possible to rationalize the resources of the urban health system to improve the availability and quality of medical care for people with cardiovascular diseases at the pre-hospital stage.

Regional Features of the Incidence of Diseases of the Circulatory System in the Population of the Orenburg Region

2021 ◽  
pp. 4-9
Author(s):  
EL Borshchuk ◽  
DN Begun ◽  
YuV Varennikova ◽  
Duisembaeva AN
Keyword(s):  
Cardiovascular Diseases ◽  
Information Technologies ◽  
Medical Information ◽  
Adult Population ◽  
Circulatory System ◽  
Practical Implementation ◽  
Orenburg Region ◽  
National Healthcare ◽  
Regional Features ◽  
Regional Project

Introduction: At present, National Healthcare and Demography Projects are being implemented in the Russian Federation and in the Orenburg Region, including the Regional Project for Prevention of Cardiovascular Diseases. Within the National Healthcare Project, the task has been set to reduce the mortality rate from diseases of the circulatory system to 450 per 100,000 population by the year 2024 (from 573.6 per 100,000 population registered in 2018). The regional goal is 477 per 100,000 population in 2024 (against 635.5 per 100,000 population in the year 2018). However, practical implementation of the project shows that in 2019–2020, the targets were not achieved. It is, therefore, important to monitor this indicator and to assess preventable losses associated with diseases of the circulatory system by all possible means including with the use of information technologies. Our objective was to establish regional features of the structure, dynamics, and rates of diseases of the circulatory system among the population of the region and to determine municipalities with high rates of cardiovascular disorders. Materials and methods: We used data of the Russian statistical collections “Medical and Demographic Indicators”, “Morbidity of the Population of Russia”, and annual information and analytical collections of the Orenburg Medical Information and Analytical Center for the years 2009–2018 to conduct a time series analysis. Results: We observed an increase in the incidence rate of diseases of the circulatory system in the population of the Orenburg Region over the ten-year period. The maximum regional rate of 67.0 ± 1.8 per 1,000 population was registered in 2018 while the minimum rate was observed in 2009 and equaled 27.0 ± 0.27 per 1,000 population. Conclusion: The study period was characterized by an increase in the incidence of diseases of the circulatory system accompanied by a statistically significant decrease in the prevalence of cardiovascular diseases in the adult population of the Orenburg Region. The diseases related to high blood pressure ranked first.

scholarly journals Cardiovascular diseases burden in Italy, 1990–2017: the Global Burden of Disease Study

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
C Fornari ◽  
P A Cortesi ◽  
F Madotto ◽  
S Conti ◽  
G Crotti ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Diseases ◽  
National Health ◽  
Population Aging ◽  
National Health System ◽  
Total Mortality ◽  
Premature Death ◽  
Global Burden ◽  
High Systolic Blood Pressure ◽  
Life Years

Abstract Background Cardiovascular diseases (CVDs) are still the leading cause of mortality, morbidity and disability in Europe. Consequently, an exhaustive estimation of CVDs burden and cardiovascular risk factors impact is crucial for healthcare planning and resource allocation. In Italy, data on CVDs burden are sparse. This study aims to assess the global Italian CVDs burden and to analyze time changes from 1990 to 2017 within the country and in comparison to other European states. Methods We used data from the 2017 Global Burden of Diseases (GBD) study to estimate CVDs prevalence, mortality and disability-adjusted life-years (DALYs) in Italy from 1990 to 2017. We also analyzed burden attributable to CVDs-related risk factors. Finally, Italian estimations were compared to those of the other 28 European Union countries. Results CVDs were still the first cause of death (34.8% of total mortality) in Italy in 2017. A significant decrease in CVDs burden was observed since 1990: age-standardized prevalence (-12.7%), mortality rate (-53.75%), and DALYs rate (-55.54%) all decreased. Similar patterns were observed also in the majority of European countries. Despite these trends, all-ages CVDs prevalent cases increased from 5.75 million to 7.49 million. More than 80% of CVDs burden could be attributed to known modifiable risk factors such as high systolic blood pressure, dietary risks, high LDL cholesterol, and impaired kidney function. Conclusions Data showed a decline in cardiovascular mortality and DALYs, which reflects the success in terms of reducing disability, premature death and early incidence of CVDs. However, the burden of CVDs is still high, as population aging and the increased prevalent cases require more access to care and generate more years lived with disability, which in turn leads to higher costs for the National Health Service and society. More efficient prevention strategies at community and individual level are needed. Key messages Despite decreasing trends in CVDs mortality and DALYs, the burden of CVDs is still high in Italy. A joined approach of the National Health System stakeholders is needed to keep reducing the CVDs burden.

Impact of the period of the day on mortality and major cardiovascular complications after vascular surgeries

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
F.A.M Cardozo ◽  
T Artioli ◽  
B Caramelli ◽  
D Calderaro ◽  
P.C Yu ◽  
...  
Keyword(s):  
Multivariable Analysis ◽  
Total Mortality ◽  
Mortality Rates ◽  
Cardiovascular Complications ◽  
Cardiac Complications ◽  
Funding Source ◽  
Confounding Variables ◽  
Significant Difference ◽  
One Year ◽  
Night Period

Abstract Introduction Patients submitted to arterial vascular surgeries are at a high risk of postoperative cardiac and non-cardiac complications, therefore developing strategies to lower perioperative complications is essential to optimize outcomes for this subgroup. Recent studies have suggested that the period of the day in which surgeries are performed may influence postoperative major cardiovascular complications but there is still no evidence of this association in vascular surgeries. Purpose Our goal is to evaluate whether the period of the day in which surgeries are performed may influence mortality and cardiovascular outcomes in patients undergoing non-cardiac vascular procedures. Methods Patients who underwent non-cardiac vascular surgeries between 2012 and 2018 were prospectively included at our cohort. For this analysis, subjects were categorized into two groups: those who underwent surgery in the morning (7am - 12am) and those who underwent surgery in the afternoon/night (12:01pm - 6:59am). The primary endpoints were to compare the incidence of major adverse cardiac events (MACE - acute myocardial infarction, acute heart failure, arrhythmias, and cardiovascular death) and total mortality between morning and afternoon/night surgeries within 30 days and one year. The secondary endpoint was the incidence of perioperative myocardial injury (PMI) in both groups. PMI was defined as an absolute elevation of high-sensitivity cardiac troponin T (hs-cTnT) concentrations ≥14ng/L. Multivariable analysis using Cox proportional regression (with Hazard Ratio – HR and Confidence Interval – 95% CI) was performed to adjust for confounding variables, including emergency and urgent surgeries. Results Of 1267 patients included, 1002 (79.1%) underwent vascular surgery in the morning and 265 (20.9%) in the afternoon/night. After adjusting for confounding variables, the incidence of MACE at 30 days was higher among those who underwent surgery in the afternoon/night period (37.4% vs 20.4% – HR 1.43, 95% CI: 1.10–1.85; p=0.008). Mortality rates were also elevated in the afternoon/night group (21.5% vs 9.9%, HR 1.59, 95% CI: 1.10–2.29; p=0.013). After one-year of follow-up the worst outcomes persisted in patients operated in the afternoon/night: higher incidence of MACE (37.7% vs 21.2%, HR 1.37, 95% CI: 1.06–1.78; p=0.017) and mortality (35.8% vs 17.6%, HR 1.72, 95% CI 1.31–2.27; p<0.001). There was no significant difference in the incidence of PMI between groups (p=0.8). Conclusions In this group of patients, being operated in the afternoon/night period was independently associated with increased mortality rates and incidence of MACE. Mortality and MACE at one year Funding Acknowledgement Type of funding source: Foundation. Main funding source(s): FAPESP - Fundação de Amparo a Pesquisa do Estado de São Paulo

scholarly journals Osteoprotegerin and RANKL-RANK-OPG-TRAIL signalling axis in heart failure and other cardiovascular diseases

2021 ◽  
Author(s):  
Mieczysław Dutka ◽  
Rafał Bobiński ◽  
Wojciech Wojakowski ◽  
Tomasz Francuz ◽  
Celina Pająk ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Cardiovascular Diseases ◽  
Vascular Endothelial Cells ◽  
Circulatory System ◽  
Prognostic Indicator ◽  
High Plasma ◽  
Mechanisms Of Action ◽  
Left Ventricular ◽  
High Ratio

AbstractOsteoprotegerin (OPG) is a glycoprotein involved in the regulation of bone remodelling. OPG regulates osteoclast activity by blocking the interaction between the receptor activator of nuclear factor kappa B (RANK) and its ligand (RANKL). More and more studies confirm the relationship between OPG and cardiovascular diseases. Numerous studies have confirmed that a high plasma concentration of OPG and a low concentration of tumour necrosis factor–related apoptosis inducing ligand (TRAIL) together with a high OPG/TRAIL ratio are predictors of poor prognosis in patients with myocardial infarction. A high plasma OPG concentration and a high ratio of OPG/TRAIL in the acute myocardial infarction are a prognostic indicator of adverse left ventricular remodelling and of the development of heart failure. Ever more data indicates the participation of OPG in the regulation of the function of vascular endothelial cells and the initiation of the atherosclerotic process in the arteries. Additionally, it has been shown that TRAIL has a protective effect on blood vessels and exerts an anti-atherosclerotic effect. The mechanisms of action of both OPG and TRAIL within the cells of the vascular wall are complex and remain largely unclear. However, these mechanisms of action as well as their interaction in the local vascular environment are of great interest to researchers. This article presents the current state of knowledge on the mechanisms of action of OPG and TRAIL in the circulatory system and their role in cardiovascular diseases. Understanding these mechanisms may allow their use as a therapeutic target in cardiovascular diseases in the future.

ORGANIZATIONAL AND METHODOLOGICAL APPROACHES TO THE RATIONAL MANAGEMENT OF THE PROCESS OF REDUCING MORTALITY FROM DISEASES OF THE CIRCULATORY SYSTEM

Vestnik ◽  
2021 ◽  
pp. 280-283
Author(s):  
М.А. Камалиев ◽  
С.Х. Алимбаева
Keyword(s):  
Mortality Rate ◽  
Medical Care ◽  
Circulatory System ◽  
The World ◽  
Rational Management ◽  
Methodological Approaches

Во всем мире болезни системы кровообращения считаются важнейшей проблемой потому, что показатели смертности от них превышают показатели смертности от любой другой причины. Обоснован перечень организационных резервов совершенствования медицинской помощи населению при болезнях системы кровообращения на основе усиления профилактической деятельности, ориентированной на конечные результаты. Diseases of the circulatory system are considered a serious problem all over the world, as the mortality rate from them exceeds the mortality rate from any other causes. The list of organizational reserves for improving medical care for the population with diseases of the circulatory system on the basis of strengthening preventive activities focused on the final results is justified.

ADVERSE METEOROLOGICAL SITUATION AS A RISK FACTOR FOR CARDIOVASCULAR DISEASES

2021 ◽  
pp. 28-33
Author(s):  
Kolyagina N.M. ◽  
Berezhnova T.A. ◽  
Kulintsova Ya.V. ◽  
Elistratova O.S. ◽  
Drapalyuk M.A.
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Cardiovascular Diseases ◽  
Medical Care ◽  
Air Temperature ◽  
Meteorological Factors ◽  
Vascular Lesions ◽  
Weather Sensitivity ◽  
Access To Medical Care ◽  
The City

Relevance. Exacerbation of the disease, as a rule, leads to the patient seeking medical help. In this regard, data on the population's access to medical care can serve as an indicator of the exacerbation of the disease. Aim: to analyze meteorological risk factors that contribute to the development of cardiovascular diseases. Material and methods. The ratio of the average number of cases of requests for medical care on unfavorable days for meteorological factors to the average number of cases of requests per day for medical care during the year was calculated. Using software tools (STATISTICA Base V6. 1), the type of data distribution was estimated, and a correlation analysis of the likely relationship between the number of medical care requests and the indicators of meteorological factors was carried out. Results. As a result of the study, it was found that the average number of cases of medical care requests on hot days (air temperature over + 300C) is 1.1-1.4 times higher than the average number of cases of requests per day for the same reasons (diagnoses) during the year and is abnormal for the territory of the city of Voronezh, due to such diagnoses as hypertension without heart failure, brain vascular lesions (specified), cerebrovascular disease, hypertension with heart failure. Conclusions. Thus, it was found that one of the meteorological risk factors for the formation of cardiovascular pathology is high air temperature (above + 300C), which is the goal for the implementation of the main directions of prevention of increased weather sensitivity and treatment of weather-dependent patients.

Emergencies in diseases of the circulatory system of the adult population of the Khabarovsk krai: the current status and trends

2021 ◽  
Vol 89 (3) ◽  
pp. 16-25
Author(s):  
K.P. Topalov ◽  
◽  
T.V. Zaitseva ◽  
T.G. Trembach ◽  
◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Cerebral Circulation ◽  
Adult Population ◽  
Circulatory System ◽  
Cerebrovascular Diseases ◽  
Current Status ◽  
Newly Diagnosed ◽  
Khabarovsk Krai ◽  
Coronary Syndrome ◽  
Status And Trends

The indicators of morbidity of the adult population of the Khabarovsk Krai with diseases of the circulatory system and mortality caused by these diseases in 2002–2019 were studied. Special attention is paid to urgent pathology - acute coronary syndrome and acute disorders of cerebral circulation. It was found that acute coronary syndrome and acute disorders of cerebral circulation in the region account for about 75–85% of all newly diagnosed diseases of the circulatory system - ischemic heart disease, cerebrovascular diseases; they result in up to 32% of deaths from diseases of the circulatory system

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