scholarly journals The Difference in The Activity of Ethanol Extracts of Leaves of Anti Diabetic tin (Ficus Carica l.) Leaf, Rambutan (Nephelium Lappaceum) and Persimmon (Diospyros Ft L) on The White Mancit on Streptozotocin Induced

2019 ◽  
Vol 1 (1) ◽  
pp. 49-55
Author(s):  
Nurlinawati ◽  
Kamariyah ◽  
Yosi Oktarina ◽  
Sri Mulyani

Diabetes mellitus is a metabolic syndrome most public figures around the globe with events 1-8%. This disease occurs when insulin in insulin production or tidakcukup may not function properly or the amount of insulin enough but it works less well characterized by high levels of sugar in the blood. The Research Design used in this research is experimental design pre test and post test design group, where only when the post test (end) only performed measurements. Research use only post test where observations are conducted as many as 3 times at the time after thera-py/experiment. Observations made after experiment (X 2) called the Post Test. It is known that a group of white male mice strain spreague dawley fed leaves etha-nol extract rambutan (Ficus carica l.), shows a decrease in blood sugar levels better when compared to the Group of esktrak penginduksi with a persimmon the same form of induction of streptozoto-cin. Ethanol extracts of leaves of Rambutan (Nephelium lappaceum) Note can lower the blood sugar levels of 9 mg/dl and persimmon (Diospyros ft L) can lower the blood sugar levels of 5.3 mg/dl, while the leaves of Tin (Ficus carica l.) showed can increase blood sugar levels in mice white male spreague dawley strain induced streptozotocin.Keyword: self-acceptance, chronic kidney failure, hemodialysis.

2020 ◽  
Vol 5 (1) ◽  
pp. 16-24
Author(s):  
Carmelita Barros ◽  
Fitri Arofiati

ABSTRACT Diabetes mellitus (DM) in Indonesia is better known as diabetes and in Timor Leste DM known as Ra'an Midar has become a very serious health problem, and is the most common endocrine disease. Diabetes mellitus is a degenerative disease that is characterized by metabolic disorders or pancreatic damage so that the pancreas is unable to produce enough insulin to the maximum so that it can cause insulin deficiency in the body both absolute and relative can increase blood sugar levels or hyperglycemia. Data from the Dili District Health Office in 2018 showed that there were 2690 patients with diabetes mellitus, so that diabetic foot exercises were needed. The purpose of this study was to determine the effect of Tetum Language Diabetes Foot Gymnastic Education on Lower Circulation and Lower Blood Sugar Levels at the Saude Comoro Center, Dili, Timor Leste. Method : using the Pre-Experiment method. Independent variable: Education of Tetum Language Diabetes Foot Gymnastics Education, dependent variable: Circulation of Lower Extremity and Blood Sugar Level at a Time. Population 100 people, sample 28 people, sample technique: simple random, data collection: Examination of blood sugar levels, blood circulation, statistical tests: Wilcoxon Test. Results : Most respondents who had good blood circulation were 15 pre- test (53.6%) and 18 post-test (64.3%). And the majority of respondents whose blood sugar levels were good were 14 people pre-test (50.0%) and 20 people post test (71.4%). Based on the results of statistical tests using the Wilcoxon Signed Rank Test, the value of blood circulation is a significant level of 0.005 and the blood sugar level is at a significant level of 0,000. Conclusion : Conclusion there is the influence of Education on Tetun Language Diabetes Foot Gymnastics on Lower Extracurricular Circulation and Blood Sugar Levels At the Saude Comoro Center, Dili, Timor Leste.  Keyword: Leg exercise, lower extremity bloodd circulation, Blood sugar levels, Diabetes mellitus.


2019 ◽  
Vol 6 (1) ◽  
pp. 77-80
Author(s):  
Ni Wayan Suniyadewi ◽  
G.N Indraguna Pinatih

Abstract Objective Carbohydrates, proteins, and fats are energy sources needed by the body for performing daily activities and generating primary energy substances. In women who have undergone menopause, the function of thyroid hormone in their body begins to decline and thus affects the ability of the body to produce energy. The purpose of this study was to determine the correlation between the intakes of carbohydrates, proteins, and fats and random blood sugar levels in menopausal women. Methods This study was a correlational analytical research with a cross-sectional design, which was conducted in 72 menopausal women recruited by the purposive sampling technique. In this study, a 24-hour food recall form was used, and randomized blood sugar levels were measured using a glucometer. The analysis of the data was performed using a Pearson product moment and multiple linear regression. Results Carbohydrates and fats together affected random blood sugar levels with an F-value of 25.810 and a p-value of 0.000. Meanwhile, adjusted R2 showed the value of 0.411, indicating that the difference in the intake of carbohydrates and fats together affected random blood sugar levels by 41.1%. Conclusions Intake of carbohydrates and fats affected random blood sugar levels, whereas the rest were influenced by other factors, and protein intake was unrelated to random blood sugar levels in menopausal women.


2021 ◽  
Vol 2 (1) ◽  
pp. 105-112
Author(s):  
Dara Ananda ◽  
Pratama Zendrato ◽  
Edlin ◽  
Andre Budi

A B S T R A C TThis study aims to determine the effect of paprika ethanol (capsicum annuum) onblood sugar levels of alloxan-induced Wistar rats (rattus norvegicus). This type ofresearch is experimental. The method used was pre test and post test with controlgroup design. The results of this study indicate that for Post Test 1 or after beinggiven treatment for 7 days, the average result shows that there is an effect of givingred paprika ethanol extract on blood sugar levels in Wistar rats where the significantvalue of each treatment is all less than 0.05. For Post Test 2 or after being giventreatment for 14 days, only at a dose of 250 that has no effect on blood sugar levelsof the rats, because the significant value is 0.813 greater than 0.05, for othertreatments it has a significant effect because the significant value is more smallerthan 0.05.


1969 ◽  
Vol 29 (2) ◽  
pp. 463-466 ◽  
Author(s):  
Robert G. Gibby ◽  
Robert G. Gibby ◽  
John C. Townsend

The purpose of the study was to determine the stability of the rate of change of heart rate (instantaneous heart rate) from non-stress to stress conditions. Ss were 80 white male science or engineering majors, all free from emotional or physical disorders. They were subjected to psychological and physiological stress, and all were required to show an increase from pre-stress to post-stress conditions in both subjective and physiological indexes of stress. Pre- and post-stress rate of change of heart-rate scores were compared. The difference between the mean scores was not significant ( p < .10). The correlation between pre- and post-test rate of change was .64. It was concluded that the rate of change of heart-rate is a stable parameter.


Author(s):  
Putri Dafriani ◽  
Roza Marlinda ◽  
Eliza Arman ◽  
Meldafia Idaman

Background: Diabetes mellitus (DM), a metabolic disorder characterized by an increasing of blood sugar (hyperglycemia). Medication is one of the seven pillars of diabetes managementt. Garlic (Allium sativum), an alternative herb, also has an antidiabetic effect. The purpose of this study was to investigate the effect of garlic on the blood sugar level in type 2 diabetes mellitus.Methods: This study was a quasi-experimental design with two group post-test design. The participants were DM patients who only take medication without any supplemental herbs. The respondents were divided into two group; intervention group, given antidiabetic drugs and consume garlic 3 pieces of garlic/day for 2 weeks and control group only got antidiabetic drugs. Data were collected by performing blood sugar measurement using glucose-check on all respondents using capillary blood in the fingertips. Second measurement were taken after monitoring the consumption of garlic together with drugs for two weeks. Hypothesis testing used independent T-Test test.Results: The study result found that the average of blood sugar level after administering the treatment is 240 mg/dl in the intervention group, and 284 mg/dl in control group. It can be concluded that the administration of 3 pieces of garlic combining with antidiabetic drugs for 2 weeks has not been able to reduce blood sugar levels into normal limits.Conclusions: This combination found to lowering the blood sugar levels in a significant amount compare to only drugs. The length of the therapy could consider as a significant predictor.


Author(s):  
Yuni Irianti ◽  
Ngadiani Ngadiani

We report the supplementation of noni (Morinda citrifolia) to decrease blood sugar levels in patients with diabetes mellitus Brawijaya Hospital Surabaya, and noni problems whether supplementation is effective in reducing blood sugar levels in diabetes patients mellitus.The goal of this study was to determine the effectiveness of capsule morinda to decrease blood sugar levels in patients with Diabetes Mellitus in Brawijaya Hospital Surabaya. This type of research is to ekperimem quasi control group design with pre-test and post test. The population in this study are patients with diabetes mellitus in hospital outpatient Brawijaya. The sampling technique with a number of 60 people who were divided into 30 groups of control (can drug from a doctor) and 30 in the experimental group (can medicine from the doctor and consumption of noni capsules) .Instrumen this study is the laboratory results of random blood sugar levels with the tools glucometer ( gluko Dr). Data analysis was performed using univariate and bivariate (parametric test, Kolmogorov-Smirnov test z and Independent T-Test). From the results, no significant difference the difference in the results of pre-test and post-test in the control group and the experiment is p = 0.020 (<0.05), then the alternative hypothesis (Ha) is accepted (the results are meaningful). It is concluded that supplementation of noni effective in helping to decrease blood sugar levels of patients with diabetes mellitus, it is advisable to consume noni capsules and routine checks of blood sugar levels so that the blood sugar levels under control.


2020 ◽  
Vol 11 (1) ◽  
pp. 12-20
Author(s):  
Adinda Febriyanti ◽  
Cau Kim Jiu ◽  
Sri Ariyanti

Background: Diabetes Militus is a group of metabolic diseases characterized by hyperglycemia or an increase in blood sugar that occurs due to abnormal insulin secretion. Diabetes Mellitus in the world is one of the health problems that cause death. IDF data (2013) says Indonesia is the seventh largest country in the case of Diabetes Militus. Diabetes Militus in West Kalimantan Province increased from 0.6% in 2007 to 0.8% in 2013, this number increased compared to 2012, which was 4866 cases (Pontianak City Service 2014 in Salim, I.O, 2016). Based on 30 samples taken from the Purnama Public Health Center, 15 men and 15 women were found to suffer from Diabetes Militus type 2. With a poor lifestyle so that when carrying out research many were found with more weight. Purpose: Effectiveness of Types of Honey (Forest Honey, Kelulut Honey and Livestock Honey) Against Blood Sugar Levels Research Methods: Descriptive Quantitative with a sample of 30 respondents using a quasi-experimental design with a pre-test and post-test nonequivalent control group design. Research Results: The results showed that all honey can reduce blood sugar levels, especially forest honey. The results of data analysis using Anova statistical test obtained p value Pre test 0.52> α: 0.05 and Post test 0.113> α: 0.05 showed that there were no significant values ​​of the three types of honey on the decrease in blood sugar levels. Conclusion: Based on the results of the study concluded that there was no effectiveness of the types of honey (forest honey, honey kelulut and livestock honey) to reduce blood sugar levels in the Purnama Community Health Center Keywords: Honey, Blood Sugar Levels   ABSTRAK Latar Belakang: Diabetes Militus adalah sekelompok penyakit metabolik yang ditandai dengan hiperglikemia atau peningkatan gula darah yang terjadi akibat sekresi insulin abnormal. Diabetes Mellitus di dunia adalah salah satu masalah kesehatan yang menyebabkan kematian. Data IDF (2013) mengatakan Indonesia adalah Negara terbesar ketujuh dalam kasus Diabetes Militus. Diabetes Militus di Provinsi Kalimantan Barat meningkat dari 0,6% pada tahun 2007 menjadi 0,8% pada tahun 2013, jumlah ini meningkat dibandingkan tahun 2012, yaitu 4866 kasus (Layanan Kota Pontianak 2014 di Salim, I.O, 2016). Berdasarkan 30 sampel yang diambil dari Pusat Kesehatan Masyarakat Purnama, 15 priadan 15 wanita ditemukan menderita Diabetes Militus tipe 2. Dengan gaya hidup yang buruk sehingga ketika melakukan penelitian banyak ditemukan yang lebih berat. Tujuan: Efektivitas Jenis-jenis Madu (Madu Hutan, Madu Kelulut dan Madu Ternak) Terhadap Kadar Gula Darah Metode Penelitian: Deskriptif Kuantitatif dengan sampel 30 responden menggunakan desain kuasi eksperimen dengan pre-test dan post-test nonequivalent control group design. Hasil Penelitian: Hasil penelitian menunjukkan bahwa semua madu dapat mengurangi kadar gula darah, terutama madu hutan. Hasil analisis data menggunakan uji statistic Anova diperoleh nilai p Pre test 0,52> α: 0,05 dan Post test 0,113> α: 0,05 menunjukkan bahwa tidak ada nilai signifikan ketiga jenis madu terhadap penurunan kadar gula darah. Kesimpulan: Berdasarkan hasil penelitian disimpulkan bahwa tidak ada efektifitas jenis-jenis madu (madu hutan, madu kelulut dan madu ternak) untuk menurunkan kadar gula darah di Puskesmas Purnama


2019 ◽  
Vol 7 (20) ◽  
pp. 3363-3365
Author(s):  
Sake Juli Martina ◽  
Pradeepa A. P. Govindan ◽  
Arlinda Sari Wahyuni

BACKGROUND: High incidence rate of diabetes mellitus (DM) and increased incidence of complications from DM as well as the use of less effective antidiabetic drugs and high financing to treat demands alternative therapy. AIM: This study was conducted to determine the difference in the effect of Arabica coffee gayo bean and leaf extract on blood sugar levels in healthy mice before and after the intervention of extract and fasting and postprandial blood glucose level after consumption of glucose. METHODS: This research is an experimental research study. The study used experimental animals which were divided into 8 groups which are the control group (Aquadest), group given Acarbose, the group given the Arabica coffee gayo bean extract with dosage of 50 mg, 100 mg and 200 mg in healthy mice, the group given the Arabica coffee gayo leaf extract with dosage of 30 mg, 60 mg and 120 mg in healthy mice. RESULTS: The results of the study obtained are before and after the intervention of extract showed the difference of p= 0.523 and after consumption of glucose the fasting and postprandial result showed the difference of p = 0.005. CONCLUSION: The use of Arabica coffee gayo bean and leaf extract showed a high decrease in blood glucose levels (BGL) compared to the control group.


Author(s):  
GANESH SRITHERAN PANEERSELVAM ◽  
YAMAN WALID KASSAB

Objective: To compare the performance of Cockcroft-Gault and Modification of Diet in Renal Disease (MDRD) equations in estimating kidney function in CKD patients with diabetes and hypertension. Methods: This study retrospectively reviewed medical records in Hospital Kajang. The GFR was calculated using Cockcroft-Gault and MDRD equations. Kappa Measure of Agreement was used to check the consistency of CKD staging. Wilcoxon signed-ranked tests and Bland-Altman plots were used to determine the difference of both equations. Spearman correlation was used to determine the correlation between blood pressure and blood sugar levels with eGFR. Results: Data pertaining to a total of 81 patients were extracted. Results showed 22% of the patients were staged differently (Kappa value = 0.644 [P<0.001]) and the majority of them moved down one CKD stage when MDRD equation was used instead of Cockcroft-Gault equation. Wilcoxon signed rank test demonstrated there was a significant difference (P<0.001) in eGFR using CandG and MDRD in patients with diabetes and hypertension. Furthermore, the mean difference observed was 3.78±5.56 [P<0.001]), where the Cockcroft-Gault equation measured 3.78 units higher than MDRD equation. However, the relationship between blood sugar and blood pressure with eGFR were not significant. Conclusion: There was a significant difference between Cockcroft-Gault and MDRD equations in estimating kidney function CKD patients with diabetes and hypertension.


2020 ◽  
Vol 9 (1) ◽  
pp. 15
Author(s):  
Eni Sumarliyah ◽  
Dede Nasrullah ◽  
Sukadiono . ◽  
Desta Pankyano

Diabetes mellitus (DM) is a metabolic disease characterized by an increase in blood sugar levels. Blood sugar levels in patients with DM are mostly challenging to control, and this will threaten the occurrence of complications. Alternative therapies used are active flavonoids in reducing blood glucose. The purpose of this study was to analyze the decrease in blood sugar levels by administering cherry leaves stew and black onions to mice (mus musculus). The design of this study was the Quasy Experimental design (pretest-posttest with control group design). The sample in this study was 32 mice, 16 in the intervention group, and 16 comparison groups. There are independent variables (Kersen Leaf Stew and Black Onion Extract) and the dependent variable (Blood Glucose Level). The data were collected using an observation sheet, then analyzed using the independent sample T-test and Kolmogorov Smirnov test. The results of this study showed that the pre and post administration of cherry leaf decoction was 36.5 mg/dl, and the difference between pre and post administration of black onion extract was 24.3 mg/dl. While the analysis showed p = value 0.98, it showed no difference in the effectiveness of the two extracts in reducing blood sugar levels in mice. Obtained comparative test results from the two extracts were equally effective in lowering blood sugar in mice. Thus further research needs to be done with more samples.  


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