scholarly journals The Effect of Perchloroethylene (PCE) Exposure Toward Frequency of Micronucleus Formation in Buccal Mucosal Ephitelia of Dry Cleaning Employees

2019 ◽  
Vol 20 (2) ◽  
pp. 59-62
Author(s):  
Rosmayda Ria Julianti ◽  
Ageng Brahmadhi ◽  
Muhammad Fadhol Romdhoni ◽  
Refni Riyanto

Background: Perchloroethylene is one of the main ingredients used in the dry cleaning industry. Continuous inhalation of Perchloroethylene particles can cause genetic damage that can be marked by the appearance of micronucleus. Micronucleus formation of excessive buccal mucosal is one of the early signs of malignancy in the oral cavity. Objective: To determine the effect of Perchloroethylene exposure toward frequency of micronucleus formation in buccal mucosal epithelial of dry cleaning employees in Banyumas Regency. Materials & methods: This study uses cross-sectional design with primary data that is the preparation of buccal mucosal smear from 22 dry cleaning employees as exposed group and 22 subjects are not exposed to Perchloroethylene as control group. The buccal epithelial cells are collected using a spatula and then smeared on an object glass and colored using Giemsa. Micronuclear frequencies are calculated per 1000 cells using a light microscope. Results: The difference of micronucleus frequency between two groups (p = 0.000) is obtained. The duration of work has correlation with medium correlation strength to the forming frequency of micronucleus formation, whereas age has strong correlation to the forming frequency of micronucleus formation. The correlation between age and work duration with the forming frequency of micronucleus formation is significant (p = 0.000 and p = 0.07) Conclusions: There is influence of Perchloroethylene exposure toward frequency of micronucleus formation. The duration of work and age are significantly correlated with the forming frequency of micronucleus formation. J MEDICINE JUL 2019; 20 (2) : 59-62

2017 ◽  
Vol 4 (1) ◽  
pp. 27
Author(s):  
Riezqia Ayu Wulandari ◽  
Sandy Christiono ◽  
Niluh Ringga

Background: Down syndrome (DS) is a congenital disorder caused by abnormalities of chromosome 21, resulting in migration defect of neutrophils, specifically in GCF as a marker of increasing periodontal infection. This study aimed to analyze the difference in neutrophil numbers between down syndrome and healthy children.Method: This research was an analytic observational with cross sectional design, and divided into two groups. The control group is consisted of healthy children and the other is consisted of down syndrome children. GCF was taken using paper point number 45-50 for 30 seconds, then it smeared into object glass and painted with giemsa staining. Observations was done by light microscopy with 1000 times magnification.Result: The result of studies with p<0.05 was indicating a significant difference of neutrophil numbers between children with down syndrome and the healthy group.Conclusion: This study concluded that there was a difference in neutrophil numbers due to the migration defect of neutrophils in children with down syndrome, that can cause proneness to periodontal infections.


e-GIGI ◽  
2015 ◽  
Vol 3 (2) ◽  
Author(s):  
Marsela Liwe ◽  
Christy N. Mintjelungan ◽  
Paulina N. Gunawan

Abstract: In children, caries occurs mostly at the age of 6 to 9 years. At the age of 6 years permanent molar teeth begin to erupt, therefore, they are more susceptible to caries. Moreover, at the age of 9 years, a period of mingled teeth where the number of permanent teeth and of the milk teeth are nearly the same. This study aimed to obtain the prevalence of dental caries of the first permanent molar among students of elementary schools in South Tomohon. This was a descriptive study with a cross-sectional design. The population of this study was 72 students aged 6-9 years old. Samples were obtained by using total sampling method. Primary data were obtained by examination of the teeth and mouth. The results showed that the prevalence of caries among students of elementary schools in South Tomohon was 68.1% (49 students). Based on gender, caries were most frequent among males (68.4%). Based on age, caries were most frequent among students of 8 years old (79.2%). Based on tooth element, tooth 36 had the highest incidence of caries (37.2%). Based on the severity of caries, dentine caries was the most frequent (46.51%).Keywords: dental caries, the first permanent molarAbstrak: Karies merupakan penyakit yang banyak menyerang anak-anak terutama umur 6 sampai 9 tahun. Pada umur 6 tahun gigi molar permanen sudah mulai tumbuh sehingga lebih rentan terkena karies dan umur 9 tahun merupakan periode gigi bercampur dimana jumlah gigi permanen dan gigi sulung dalam rongga mulut hampir sama. Penelitian ini bertujuan untuk mengetahui prevalensi karies gigi molar satu permanen pada anak di SD kecamatan Tomohon Selatan. Penelitian ini menggunakan metode deskriptif observasional dengan pendekatan potong lintang. Populasi penelitian yaitu anak umur 6 - 9 tahun di SD kecamatan Tomohon Selatan dengan jumlah 72 orang. Sampel penelitian digunakan total sampling. Metode pengambilan data secara primer yaitu dengan pemeriksaan gigi dan mulut. Hasil penelitian menunjukkan prevalensi karies pada anak-anak di SD kecamatan Tomohon Selatan mencapai 68,1% dengan jumlah 49 anak. Berdasarkan jenis kelamin angka kejadian karies tertinggi didapatkan pada anak laki-laki mencapai 26 anak (68,4%). Berdasarkan usia angka kejadian karies tertinggi didapatkan pada usia 8 tahun mencapai 19 anak (79,2%). Berdasarkan elemen gigi, gigi 36 merupakan yang paling tinggi angka kejadian kariesnya yaitu 32 gigi (37,2%) dan berdasarkan tingkat keparahan karies kejadian karies dentin yang paling tinggi yaitu mencapai 40 gigi (46,51%).Kata kunci: karies gigi, molar satu permanen


e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Marianne C. Jacobus ◽  
Max F.J Mantik ◽  
Adrian . Umboh

Abstract: Haemoglobin is the main component of red blood cells that serves as a transporter of oxygen and carbon dioxide in the blood. The normal range of haemoglobin values can be used to determine the degree of anemia according to age and gender. Geographical condition such as altitude influences the haemoglobin value. This study aimed to obtain the difference of haemoglobin levels between teenagers with good nutrition status who live at the highland and those at the seaside. This was an observational analytical study with a cross sectional design. Samples were students with good nutrition status of SMPN 3 Tomohon (living at the highland) and those of SMP Kristen Nazaret Tuminting (living at the seaside). There were 60 students who met the inclusion criteria as follows: adolescent, good nutrition status, healthy, aged 13-15 years, lived at the highland or at the seaside ≥ 6 month, and willing to be performed blood examinations, and had been approved by their parents. The Mann-Whitney test for the difference between haemoglobin levels of the two groups showed a p value < 0,001. Conclusion: There was a very significant difference between haemoglobin levels of good nutrition teenagers who lived at the highland and at the seaside. Keywords: haemoglobin levels, good nutrition, teenagers, highland, seaside  Abstrak: Hemoglobin merupakan komponen utama sel darah merah dan berfungsi sebagai transporter oksigen dan karbon dioksida dalam darah. Batas normal nilai hemoglobin dapat digunakan untuk menetapkan derajat anemia, dengan distribusi usia dan jenis kelamin spesifik didasarkan pada sampel referensi sehat. Kondisi geografis, seperti ketinggian tempat dari permukaan laut menjadi faktor pertimbangan dalam distribusi nilai normal hemoglobin. Penelitian ini bertujuan untuk mendapatkan perbedaan kadar hemoglobin antara remaja gizi baik yang tinggal di pegunungan dengan yang tinggal di tepi pantai. Jenis penelitian ini analitik-observasional dengan desain potong lintang. Sampel penelitian yaitu remaja gizi baik yang tinggal di pegunungan yaitu siswa SMPN 3 Tomohon dan yang di tepi pantai yaitu siswa SMP Kristen Nazaret Tuminting. Subjek penelitian berjumlah 60 remaja yang memenuhi kriteria inklusi yaitu gizi baik, sehat, berumur 13-15 tahun, berdomisili di pegunungan atau tepi pantai ≥6 bulan, bersedia dilakukan pemeriksaan darah, dan telah disetujui oleh orang tua. Data yang diperoleh dianalisis menggunakan uji Mann-Whitney dengan bantuan program SPSS. Hasil uji Mann-Whitney mengenai perbedaan kadar hemoglobin antara kedua kelompok menunjukkan nila p <0,001. Simpulan: Terdapat perbedaan yang sangat bermakna kadar hemoglobin remaja gizi baik yang tinggal di pegunungan dengan di tepi pantai.Kata kunci: kadar hemoglobin, remaja gizi baik, pegunungan, tepi pantai


Author(s):  
Raditya Angga Pradipta

Logging the forest production is a high risk work. The condition of the forest acreage is difficult, the imbalance between the tools used by condition of the field and the skills of workers can lead to accidents. One of supporting job in the process of logging the forest production is the operation of the chainsaw that has hazards and risks which must be controlled. The main objective of this research was to risk assessment in the operational of the chainsaw in the work to cutting down trees in Perhutani KPH Madiun. This research was an observational research that conducted using cross sectional design and descriptive analysis. Data were used primary data based on interviews, observations and secondary data collected from the company. This research performed based on work activities of operating chainsaw. The result showed that based on idetification of hazards in activities of operating chainsaw in cutting trees, there were18 hazards Risk assessment showed that from 18 pure risks, there were 4 low risks,7 medium risks and 7 high risks. The conclusion from this research is the risk most dominant obtained from the risk assessment is high risk and risks while each one had the amount of 7 danger or 39 % of all the potential here hazards, to at a job should not be continued, work that needs to be set repeated or attempts to control at work to reduce the risk. Control must be reviewed for conformity before work began.Keywords: cut timber, identification hazards, risk assessment


2017 ◽  
Vol 4 (2) ◽  
Author(s):  
Dr. Syeda Razia Bukhari ◽  
Syeda Ishrat Fatima ◽  
Amenah Rashid ◽  
Farhana Saba

The aim of the research is to investigate that emotional intelligence and self-esteem in male and female school students. The present research design is research cross sectional design.  Sample contained 200 students (100 =male, 100= female)   (mean age = 14.16, SD = 0.740) all belonging to the upper, middle and lower Scio economic status. Whole sample was collected from different schools of Karachi, Pakistan with the help of convenient sampling technique. First, the confidentiality about the participants demographic information was assured after that about the purpose and procedure of research explained to participants. The participants who given consent of participation in research, the demographic form, Urdu version of Rosenberg Self-Esteem Scale (Rosenberg, 1965), and Trait Emotional Intelligence Questionnaire (TEIQue) (K.V. Petrides) were administered on them. Statistical Analysis (t-Test for independent) applied to assess the difference of emotional intelligence and self esteem among male and female.The results reveals there is significant difference among emotional intelligence of male and female school students (t (198) = 6.597, P< .05) and there is also significant difference in self esteem of male and female school students (t (198) = 2.837, P< .05).


Author(s):  
Aprilia Aprisanti Reyani

Latar Belakang :Kehangatan dada ibu dapat menghangatkan bayi, sehingga apabila bayi diletakan di dada ibunya segera setelah melahirkan atau dilakukan Inisiasi Menyusu Dini, dapat menurunkan resiko hipotermia dan menurunkan kematian bayi baru lahir akibat kedinginan atau hipotermia. Tujuan : Tujuan dari penelitian ini adalah untuk mengetahui perbedaan suhu tubuh bayi baru lahir antara bayi yang berhasil melakukan IMD dan bayi yang tidak berhasil melakukan IMD Metode  :Analitik,desain cross sectional,populasi semua bayi baru lahir, sampel bayi barulahir, teknik Non Random Sampling, pengumpulan data dengan menggunakan Lembar Observasi dengan menggunakan uji Chi-Square dengan nilai signifikan α = 0.05 yaitu bila hasil uji statistik menunjukan p ≤ α maka H0 ditolak. Hasil      :Suhu tubuh bayi baru lahir yang berhasil melakukan IMD sebagianbesardengansuhutubuhtidakhipotermisebanyak 20 bayi (87%) Suhu tubuh bayi baru lahir yang tidak berhasil melakukan IMD sebagianbesardengansuhutubuhhipotermisebanyak 8 bayi (66,7%). Dari hasil uji statistik diperoleh hasil nilai p = 0,005 < α = 0.05 maka H1 diterima, artinya ada Perbedaan suhu tubuh bayi baru lahir yang berhasil melakukan IMD dan yang tidak berhasil melakukan IMD Kesimpulan :Terdapat perbedaan suhu tubuh bayi baru lahir antara bayi yang berhasil melakukan IMD dan bayi yang tidak berhasil melakukan IMD.   Kata kunci : Inisiasi Menyusu Dini, Suhu Tubuh Bayi Baru Lahir                                                                                               THE DIFFERENCE BODY TEMPERATURE BETWEEN BABIES WHO SUCCESSFULLY INITIATE BREASTFEEDING EARLY AND BABIESWHO FAIL TO INITIATE EARLY BREASTFEEDING AT RSIA KIRANA SIDOARJO 2019  Background : The warmth of the mother’s chest can warm the baby, so that when the baby is in the mother’s breast immediately after birth or initiated early breastfeeding can reduce the mortality rate of newborns due to hypotermia.Purpose :the purpose of this study was to determine the difference in body temperature of newborns between infants who successfully initiated early breastfeeding and infants who did not succeed in initiating early breastfeedingMethods : analytical, cross sectional design, population 40 newborns, samples 35 newborns, Non Random Sampling techniques, the data accumulation using observation sheets and using chi-square test, with significant value α = 0.05 is when the statistical test results show p ≤ α then Ho is rejected.Result : The body temperature of the newborn who succeeded in initiating early breastfeeding was 36.78ºC with 23 (65.7%) of infants none having hypothermia, the newborn baby's body temperature that did not succeed in doing this early breastfeeding was 35.78ºC With 8 infants experiencing hypothermia, while 4 babies with normal temperature. From the results of statistical tests obtained results with the value p = 0,000 <α = 0.05 then H1 accepted, meaning there is a difference in body temperature of a newborn who successfully initiated early breastfeeding and who did not succeed in Early Breastfeeding Initiation. Conclusion : There is a difference in the body temperature of a newborn between infants who successfully initiated breastfeeding and infants who are not successful in initiating early breastfeeding....Keywords : Early breastfeedinginitiation, newborns temperature


e-GIGI ◽  
2019 ◽  
Vol 7 (2) ◽  
Author(s):  
Lidia A. Kewo ◽  
Damajanty H.C. Pangemanan ◽  
Aurelia Supit

Abstract: To date, there are lots of documentations about the adverse effects of smoking on the oral cavity. Albeit, smoking is still considered as a casual thing in our community. Chemicals contained in the cigarette smoke can irritate the gums and soft tissues of the mouth, thus inhibiting wound healing after tooth extraction. This study was aimed to determine the difference in post-extraction dental wound healing between smokers and non-smokers. This was a comparative analytical study with a cross sectional design. Samples were obtained by using total sampling method. Subjects consisted of 16 smokers and 16 non-smokers that fulfilled the study eligibility criteria. Their oral cavities were examined to check the signs of inflammation (calor, dolor, rubor, tumor, and functio laesa). The results showed that there was a difference in post-extraction wound healing in inflammatory phase between smokers and non-smokers. As many as 9.4% of smoker patients and 34.4% of non-smoker patients recovered at 7 days post extraction. The Mann Whitney U test showed a p-value of 0.005. In conclusion, there was a significant difference in post-extraction wound healing between smokers and non-smokers.Keywords: smokers, non-smokers tooth extraction, wound healing Abstrak: Kebiasaan merokok bukan merupakan hal asing di masyarakat walaupun banyak dokumentasi mengenai akibat buruk dari merokok terhadap rongga mulut. Bahan kimia yang terdapat dalam asap rokok dapat mengiritasi gusi dan jaringan lunak mulut sehingga menghambat penyembuhan luka pasca ekstraksi gigi. Penelitian ini bertujuan untuk mengetahui perbedaan penyembuhan luka pasca ekstraksi gigi antara pasien perokok dengan bukan perokok. Jenis penelitian ialah analitik komparatif dengan desain potong lintang. Pengambilan sampel menggunakan total sampling yang memenuhi kriteria penelitian. Terdapat sebanyak 16 orang perokok dan 16 orang bukan perokok sebagai subyek penelitian. Pemeriksaan rongga mulut dilakukan untuk melihat tanda-tanda inflamasi (kalor, dolor, rubor, tumor, dan fungsio laesa). Hasil penelitian menunjukkan terdapat perbedaan penyembuhan luka 7 hari pasca ekstraksi gigi pada fase inflamasi antara pasien perokok dengan yang bukan perokok; sebanyak 9,4% pasien perokok dan 34,4% pasien bukan perokok yang sudah sembuh. Hasil uji Mann Whitney U mendapatkan nilai p=0,005. Simpulan penelitian ini ialah terdapat perbedaan bermakna dalam penyembuhan luka pasca ekstraksi gigi antara pasien perokok dengan yang bukan perokokKata kunci: perokok, bukan perokok, ekstraksi gigi, penyembuhan luka


2018 ◽  
Vol 5 (3) ◽  
pp. 383
Author(s):  
Sofa Nutrima Rismawati

ABSTRACTFree Number of larvae (ABJ) in RW 15, Wonokusumo Village is 85%. However, the incidence of Dengue Hemorrhagic Fever (DHF) is still high, ie 17 cases. The high incidence rate of DHF is due to the interaction between host, agent and environment. Host in terms of behavior, dengue virus as an agent and environment derived from the surrounding conditions that can cause and trigger the spread of DHF. The purpose of this research is to analyze the relationship of host and environment behavior to the occurrence of DHF in RW 15. This research using cross sectional design. Random sampling using the guy method. How to calculate the method guy is 10% of the population so that obtained a sample of 78 respondents. Primary data collection technique is done through indepth interview and filling questionnaire. Secondary data collection was obtained from Wonokusumo Puskemas report and report from Surabaya City Health Office. The research was conducted in RW 15. The result of bivariate statistic test showed significant relation between knowledge, attitude, action and environment against DHF incidence with p> α, 0,00> 0,05. The conclusion of this research is that there is host and environment interaction to DHF incidence. Suggestion of this research is procurement of work program every month, independent larvae monitoring movement by society and 3M movement plus every week on Thursday and procurement of training of cadre jumantik about how and regulation of dosage of abate powder according to dose.Keywords: host behavior, environment, disease Dengue Hemorrhagic Fever


2021 ◽  
Vol 17 (35) ◽  
pp. 203
Author(s):  
Benson Muchoki Mwangi ◽  
Francis N. Kibera ◽  
Mary Kinoti ◽  
Magutu P. Obara

This paper focuses on determining the influence of sales territory design on salesforce performance in the detergent manufacturing companies in Kenya. Detergents play a critical role in our everyday lives by ensuring hygiene at our personal level, in our homes, in schools, institutions, and hospitals. Detergents have gained a lot of prominence since the onset of the Corona Virus (COVID-19) disease in 2019, as it has been proved that they play an important role in curtailing the transmission of the COVID-19 disease. The Salesforce plays an important role in organizations as they are the ones who in most cases interact with customers, provide information about their organization and products, provide prices, demonstrate how products are used, train customers, provide after sales service, and resolve any issues that may arise. The study was anchored on Expectancy Theory, Resource Based Theory, Equity Theory, and Agency Theory. The study adopted positivism philosophy and used a descriptive cross sectional design. The unit of analysis was the sales people in the detergent manufacturing companies in Kenya who are members of Kenya Association of Manufacturers as per list obtained from KAM in December 2018. The study used primary data which was collected by administering semi-structured questionnaires. The data was analyzed using a combination of both descriptive and inferential statics to describe the manifestations of the variables in the data collected, simple regression model was used to test the significance of the influence of sales territory design (independent variable) on the salesforce performance (dependent variable). Fischer distribution test (F-test) was used to test the significance of the independent variable and the overall model. The p-value for the F-statistic was used to determine the robustness of the model. This was done at 95% confidence level (p<0.05). The study found a strong relationship between sales territory design and salesforce performance. This depicts that sales territory design is critical in determining salesforce performance in detergent manufacturing companies in Kenya.


bionature ◽  
2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Erpi Nurdin ◽  
Gaby Maulida Nurdin

Abstract. In the growth of microorganisms such as fungi, it is necessary to grow a medium that can provide nutrients and as an energy source. Other alternative carbohydrate sources include potatoes, breadfruit, sago, and cassava, which is a distinctive and easy to find food companion. This type of research is descriptive with cross sectional design that aims to determine the difference in alternative media variation from various sources of carbohydrate to Candida albicans. The samples were then made to be the treatment for the creation of alternative media from various carbohydrate sources that further carried out the growth test against Candida albicans. The results of the study are the average growth of colonies on alternative media from Potato carbide sources, namely 655 colonies, breadfruit 1380 colonies, cassava 862 colonies, 372 sago colonies, and semi-synthetic media as a control of 874 colonies. This indicates there is growth of Candida albicans on all alternative media so that it can be used as an alternative medium of fungi growth, as well as the best growth of Candida albicans found in the media Breadfruit Dextrose Agar. Keywords: alternative media, carbohydrate sources, Candida albicans


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