scholarly journals Antimicrobial Activity of Calcium Silicate-Based Dental Materials: A Literature Review

Antibiotics ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 865
Author(s):  
Ana Cristina Padilha Janini ◽  
Gabriela Fernanda Bombarda ◽  
Lauter Eston Pelepenko ◽  
Marina Angélica Marcano
Keyword(s):  
Antimicrobial Activity ◽  
Calcium Silicate ◽  
Dental Treatment ◽  
Dental Materials ◽  
Antimicrobial Properties ◽  
Antimicrobial Effect ◽  
Biological Tissues ◽  
Biological Properties ◽  
Treatment Techniques ◽  
Main Challenge

Endodontic biomaterials have significantly improved dental treatment techniques in several aspects now that they can be used for vital pulp treatments, as temporary intracanal medication, in definitive fillings, in apical surgeries, and for regenerative procedures. Calcium silicate-based cement is a class of dental material that is used in endodontics in direct contact with the dental structures, connective tissue, and bone. Because the material interacts with biological tissues and stimulates biomineralization processes, its properties are of major importance. The main challenge in endodontic treatments is the elimination of biofilms that are present in the root canal system anatomical complexities, as it remains even after chemical-mechanical preparation and disinfection procedures. Thus, an additional challenge for these biomaterials is to exert antimicrobial activity while maintaining their biological properties in parallel. This article reviews the literature for studies considering the antimicrobial properties of calcium silicate-based dental biomaterials used in endodontic practice. Considering the reviewed studies, it can be affirmed that the reduced antimicrobial effect exhibited by calcium silicate-based endodontic materials clearly emphasizes that all clinical procedures prior to their use must be carefully performed. Future studies for the evaluation of these materials, and especially newly proposed materials, under poly-microbial biofilms associated with endodontic diseases will be necessary.

scholarly journals Basil Essential Oil: Composition, Antimicrobial Properties, and Microencapsulation to Produce Active Chitosan Films for Food Packaging

Foods ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 121
Author(s):  
Ghita Amor ◽  
Mohammed Sabbah ◽  
Lucia Caputo ◽  
Mohamed Idbella ◽  
Vincenzo De Feo ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Essential Oil ◽  
Shelf Life ◽  
Food Packaging ◽  
Antimicrobial Properties ◽  
Edible Films ◽  
Biological Properties ◽  
Oil Composition ◽  
Packaging System ◽  
Cooked Ham

The essential oil (EO) from basil—Ocimum basilicum—was characterized, microencapsulated by vibration technology, and used to prepare a new type of packaging system designed to extend the food shelf life. The basil essential oil (BEO) chemical composition and antimicrobial activity were analyzed, as well as the morphological and biological properties of the derived BEO microcapsules (BEOMC). Analysis of BEO by gas chromatography demonstrated that the main component was linalool, whereas the study of its antimicrobial activity showed a significant inhibitory effect against all the microorganisms tested, mostly Gram-positive bacteria. Moreover, the prepared BEOMC showed a spheroidal shape and retained the EO antimicrobial activity. Finally, chitosan-based edible films were produced, grafted with BEOMC, and characterized for their physicochemical and biological properties. Since their effective antimicrobial activity was demonstrated, these films were tested as packaging system by wrapping cooked ham samples during 10 days of storage, with the aim of their possible use to extend the shelf life of the product. It was demonstrated that the obtained active film can both control the bacterial growth of the cooked ham and markedly inhibit the pH increase of the packaged food.

scholarly journals Structure and Antimicrobial Properties of Monensin A and Its Derivatives: Summary of the Achievements

2013 ◽  
Vol 2013 ◽  
pp. 1-14 ◽  
Author(s):  
Daniel Łowicki ◽  
Adam Huczyński
Keyword(s):  
Antimicrobial Activity ◽  
Lipid Membranes ◽  
Antimicrobial Properties ◽  
Biological Properties ◽  
Sodium Cation ◽  
Hydroxyl Groups ◽  
Carboxyl Group ◽  
Growth Promoter ◽  
Monensin A

In this paper structural and microbiological studies on the ionophorous antibiotic monensin A and its derivatives have been collected. Monensin A is an ionophore which selectively complexes and transports sodium cation across lipid membranes, and therefore it shows a variety of biological properties. This antibiotic is commonly used as coccidiostat and nonhormonal growth promoter. The paper focuses on both the latest and earlier achievements concerning monensin A antimicrobial activity. The activities of monensin derivatives, including modifications of hydroxyl groups and carboxyl group, are also presented.

scholarly journals Antimicrobial Effectiveness of Calcium Silicate Sealers against a Nutrient-Stressed Multispecies Biofilm

2020 ◽  
Vol 9 (9) ◽  
pp. 2722
Author(s):  
Rahul Bose ◽  
Konstantinos Ioannidis ◽  
Federico Foschi ◽  
Abdulaziz Bakhsh ◽  
Robert D. Kelly ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Calcium Silicate ◽  
Antimicrobial Properties ◽  
Laser Scanning Microscopy ◽  
Confocal Laser ◽  
Biofilm Inhibition ◽  
Planktonic Bacteria ◽  
Multispecies Biofilm ◽  
Significant Difference ◽  
Ah Plus

Purpose: This study compared the antimicrobial efficacy of calcium silicate sealers (BioRoot RCS and Total Fill BC) and conventional sealers (AH Plus and Tubli-seal) against planktonic bacteria and a nutrient-stressed multispecies biofilm. Methods: Antimicrobial properties of freshly mixed sealers were investigated using the direct contact test (DCT) and a nutrient-stressed multispecies biofilm comprised of five endodontic strains. Antimicrobial activity was determined using quantitative viable counts and confocal laser scanning microscopy (CLSM) analysis with live/dead staining. The pH of the sealers was analysed over a period of 28 days in Hanks Balanced Salt Solution (HBSS). Analysis of variance (ANOVA) with Tukey tests and the Kruskal–Wallis test were used for data analysis with a significance of 5%. Results: All endodontic sealers exhibited significant antimicrobial activity against planktonic bacteria (p < 0.05). BioRoot RCS caused a significant reduction in viable counts of the biofilms compared to AH Plus and the control (p < 0.05), while no significant difference could be observed compared to TotalFill BC and Tubli-seal (p > 0.05). CLSM analysis showed that BioRoot RCS and TotalFill BC exhibited significant biofilm inhibition compared to Tubli-seal, AH Plus and the control (p < 0.05). BioRoot RCS presented with the highest microbial killing, followed by TotalFill BC and Tubli-seal. Alkalizing activity was seen from the onset by BioRoot RCS, TotalFill BC and AH Plus. After 28 days, BioRoot RCS demonstrated the highest pH in HBSS (pH > 12). Conclusions: Calcium silicate sealers exhibited effective antimicrobial properties. This was demonstrated by superior biofilm inhibition capacity and microbial killing, with strong alkalizing activity compared to epoxy-based and zinc oxide-eugenol-based sealers.

scholarly journals Evaluation of antimicrobial activity of three important medicinal plants of South India

2019 ◽  
Vol 8 (1) ◽  
pp. 3484
Author(s):  
Gopalakrishnaiah B. ◽  
Aniel Kumar O.
Keyword(s):  
Antimicrobial Activity ◽  
Medicinal Plants ◽  
Pathogenic Bacteria ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Development Program ◽  
Antimicrobial Effect ◽  
Trichophyton Mentagrophytes ◽  
Crude Extracts ◽  
The World

India is found to be a country with rich biodiversity and enormous treasure of herbal plants and consequently called as medicinal garden of the world. Plants are the richest source of natural antimicrobial agents. In recent years drug resistance to human pathogenic bacteria has been commonly reported from all over the world. Therefore, there is a need to develop alternative antimicrobial drugs for the treatment of infectious diseases; one approach is to screen local medicinal plants for possible antimicrobial properties. The present study was designed to evaluate the antimicrobial efficacy of hexane, chloroform and methanol crude extracts of the leaves of three important medicinal plants viz., Biophytum sensitivum (L.) DC, Bougainvillea spectabilis L. and Caesalpinia bonducella (L.) Fleming, collected from in and around Visakhapatnam District. The antimicrobial activity of the crude extracts was tested against three Gram Positive bacteria (Bacillus subtilis MTCC 441, Enterococcus faecalis MTCC 439, Staphylococcus aureus MTCC 737), Three Gram Negative bacteria (Escherichia coli MTCC 443, Proteus vulgaris MTCC 426 and Pseudomonas aeruginosa MTCC 1688) and three Fungal strains (Candida albicans MTCC 227, Epidermophyton floccosum MTCC 613 and Trichophyton mentagrophytes MTCC 7687) using agar well diffusion assay. Our results demonstrated that methanol extracts of these plants leaves have concentration dependent antibacterial activity against some of the tested organisms. Further studies should be undertaken to elucidate the exact mechanism of action of antimicrobial effect to identify the active ingredients which can be used for drug development program.

scholarly journals Anthocyanins as Antimicrobial Agents of Natural Plant Origin

2011 ◽  
Vol 6 (1) ◽  
pp. 1934578X1100600 ◽  
Author(s):  
Agnieszka Cisowska ◽  
Dorota Wojnicz ◽  
Andrzej B. Hendrich
Keyword(s):  
Antimicrobial Activity ◽  
Antimicrobial Agents ◽  
Biological Effects ◽  
Antimicrobial Properties ◽  
Antimicrobial Effect ◽  
Pharmaceutical Products ◽  
Fresh Fruit ◽  
Anthocyanin Content ◽  
Human Pathogens ◽  
Food Ingredients

Anthocyanins are particularly abundant in different fruits, especially in berries. The beneficial effects of these compounds for human health have been known from at least the 16th century. Despite the great number of papers devoted to the different biological effects exerted by anthocyanins only a limited number of studies is focused on the antimicrobial activity of these compounds. Anthocyanin content of berry fruits varies from 7.5 mg/100 mg fresh fruit in redcurrant ( Ribes rubum) up to 460 mg/100 g fresh fruit in chokeberry ( Aronia melanocarpa). After consumption, anthocyanins are intensively metabolized, mainly in the intestines and liver. Glucorination, methylation and sulfation are the most typical metabolic reactions. Antimicrobial activity of crude extracts of plant phenolic compounds against human pathogens has been intensively studied to characterize and develop new healthy food ingredients as well as medical and pharmaceutical products. However, there is very little information available about the antimicrobial activity of the pure anthocyanins. In the last part of this review we present the collection of papers describing the anthocyanin profiles of different fruits (mainly berries) and the antimicrobial properties of the identified compounds. Generally, anthocyanins are active against different microbes, however Gram-positive bacteria usually are more susceptible to the anthocyanin action than Gram-negative ones. Mechanisms underlying anthocyanin activity include both membrane and intracellular interactions of these compounds. Antimicrobial activity of berries and other anthocyanin-containing fruits is likely to be caused by multiple mechanisms and synergies because they contain various compounds including anthocyanins, weak organic acids, phenolic acids, and their mixtures of different chemical forms. Therefore, the antimicrobial effect of chemically complex compounds has to be critically analyzed.

In Vitro Antimicrobial Properties of Propolis against Caries-Associated Microorganisms

2015 ◽  
Vol 752-753 ◽  
pp. 387-390
Author(s):  
Boonyanit Thaweboon ◽  
Sroisiri Thaweboon ◽  
Rattiporn Kaypetch ◽  
Thaniya Muadcheingka
Keyword(s):  
Antimicrobial Activity ◽  
Molecular Mechanisms ◽  
Biological Activities ◽  
Oral Care ◽  
Antimicrobial Properties ◽  
Antimicrobial Effect ◽  
Scientific Basis ◽  
Agar Disc ◽  
Zones Of Inhibition

Natural products have attracted much attention in recent years as a useful substance used in medicine and dental products. Propolis is a lipophilic resinous mixture collected from various plant sources by honeybees. It has been known for many biological activities including antimicrobial properties. Objective: To evaluate thein vitroantimicrobial activity of propolis against caries-associated microorganisms,Streptococcusmutans,LactobacilluscaseiandCandidaalbicans. Materials and methods: The antimicrobial activity was initially screened using agar disc diffusion and then the minimum lethal concentrations (MLCs) were determined using broth dilution technique. Chlorhexidine (0.2%) and dimethyl sulfoxide (5%) were used as positive and negative controls, respectively. Results: Propolis exhibits the zones of inhibition ranged from 15 to 18 mm forS.mutans, and from 10 to 12 mm forL.casei, but presented no activity againstC.albicans. The MLC againstS.mutanswas 2.86 mg/mL and those againstL.caseiwere 11.44 mg/mL and 12.87 mg/mL. Conclusion: Propolis shows a potent antimicrobial effect againstS.mutansandL.casei.This could provide a scientific basis to its application of usage in oral care products for the prevention of dental caries. However, further studies are necessary to evaluate other biological activities and molecular mechanisms of action as well as its cytotoxic effect.

scholarly journals Antimicrobial properties of ZnO nanoparticles incorporated in polyurethane varnish

2011 ◽  
Vol 5 (1) ◽  
pp. 41-45 ◽  
Author(s):  
Dusan Zvekic ◽  
Vladimir Srdic ◽  
Maja Karaman ◽  
Milan Matavulj
Keyword(s):  
Escherichia Coli ◽  
Saccharomyces Cerevisiae ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Zno Nanoparticles ◽  
Antimicrobial Properties ◽  
Antimicrobial Effect ◽  
Plate Test ◽  
Sacharomyces Cerevisiae

The antimicrobial effect of the ZnO nanoparticles dispersed in polyurethane varnishes was investigated. Antimicrobial activity was evaluated against three bacteria (Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa) and one strain fungi (Sacharomyces cerevisiae) by the 'pour-plate' test. It was shown that the ZnO nanoparticles efficiently inhibit growth of the colonies of Staphylococcus aureus, Pseudomonas aeruginosa and Saccharomyces cerevisiae, but their activity against Escherichia coli was found to be questionable suggesting more detailed research.

Recent Developments in the Synthesis and Antimicrobial Activity of Indole and its Derivatives

2019 ◽  
Vol 16 (1) ◽  
pp. 17-37 ◽  
Author(s):  
Jaskirat Kaur ◽  
Divya Utreja ◽  
Ekta ◽  
Nisha Jain ◽  
Shivali Sharma
Keyword(s):  
Antimicrobial Activity ◽  
Microbial Activity ◽  
Heterocyclic Compounds ◽  
Biological Activities ◽  
Antimicrobial Properties ◽  
Biological Properties ◽  
Indole Derivatives ◽  
Antimicrobial Drugs ◽  
Wide Range ◽  
Recent Developments

Background:Heterocyclic compounds containing nitrogen have been known to possess a very important role in the field of medicinal chemistry. Indole and its derivatives displayed a wide range of biological properties such as anti-inflammatory, analgesic, anti-microbial, anti-convulsant, antidepressant, anti-diabetic, antihelmintic and anti-allergic activities etc. The diverse biological activities exhibited by compounds containing indole moiety has provided the impetus to explore its anti-microbial activity in order to save the valuable life of patients. </P><P> Objective: The review focuses on the advances in the synthesis of indole derivatives and antimicrobial properties exhibited by them.Conclusion:A great deal of work has been done in order to synthesize indole derivatives and to evaluate antimicrobial potential, as indicated by the review. The information provided in this article may be helpful for the researchers for the development of efficient antimicrobial drugs.

scholarly journals FUNCTIONAL EFFECTS OF θ-DEFENSINS FROM BLOOD LEUKOCYTES OF BABOON PAPIO HAMADRYAS

2018 ◽  
pp. 66-73
Author(s):  
E. V. Tsvetkova ◽  
G. M. Aleshina ◽  
L. E. Leonovа ◽  
O. V. Shamova ◽  
E. V. Romanovskaya ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Ionic Strength ◽  
Membrane Permeability ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Antimicrobial Effect ◽  
High Ionic Strength ◽  
Papio Hamadryas ◽  
Blood Leukocytes ◽  
Minimal Inhibitory Concentrations

Aim. Study the functional properties of cationic antimicrobial peptides 0-defensins isolated from baboon Papio hamadryas blood leukocytes. Materials and methods. Baboon 0-defensins were extracted from leukocyte mass using ultrafiltration, preparative electrophoresis and reverse phase high performance liquid chromatography. The test microorganisms used were Gram-negative bacteria Escherichia coli, Gram-positive bacteria Listeria monocytogenes and Staphylococcus aureus, and fungi Candida albicans. Minimal inhibitory concentrations (MICs) were determined by testing serial dilutions of the test peptides by radial diffusion in agarose gel. Microbicidal action was evaluated by counting surviving colony forming units after incubation microorganisms with the peptides. The 0-defensins influence on E.coli membrane permeability was assessed using chromogenic markers o-nirofenil- β-D-galactopyranoside and nitrocefin. Results. The analysis of the 0-defensins antimicrobial properties showed that they produce antimicrobial activity against test microorganisms, exhibiting bactericidal and fungicidal effects at micromolar concentrations. We studied the influence of different environmental conditions (low and high ionic strength, blood serum in medium) for antimicrobial activity. It is shown that 0-defensins have the ability to increase the outer membran of E.coli permeability, however, in contrast to 0-defensins have no noticeable influence on the inner membrane permeability. Conclusion. Baboon 0-defensins isolated from blood leukocytes are effective antimicrobial agents with a broad spectrum of microbicidal action. 0-Defensins baboon unlike 0-defensins exhibit antimicrobial activity in environments with high ionic strength. 0-Defensins increase the outer membran of E.coli permeability but not the cytoplasmic membrane, suggesting that the mechanism of antimicrobial effect of these peptides other than 0-defensins.

scholarly journals Preparation of Silver-Doped Alumina Spherical Beads with Antimicrobial Properties

2018 ◽  
Vol 2018 ◽  
pp. 1-13 ◽  
Author(s):  
José Hafid Roque-Ruiz ◽  
Daniela Castillo-Ramírez ◽  
Álvaro de Jesús Ruíz-Baltazar ◽  
León Francisco Espinosa-Cristóbal ◽  
Simón Yobanny Reyes-López
Keyword(s):  
Antimicrobial Activity ◽  
Structural Characteristics ◽  
Dental Materials ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Sintering Process ◽  
E Coli ◽  
Wall Structures ◽  
Bactericidal Properties ◽  
Silver Dendrites

The synthesis of composites with antibacterial properties is of great interest for the development of new biomedical applications. The antimicrobial properties of silver have been verified against microorganisms such as bacteria, viruses, and fungi; interest in silver has been renewed, so several technologies are currently in development, especially in dental materials. The purpose of this work was to improve the parameters for producing silver-doped alumina spherical beads using sodium alginate as a sacrificial template. Alumina is a biocompatible and thermally stable ceramic, while silver was used for its bactericidal properties. The obtained spheres presented a mean diameter of 2 mm, with an irregular surface and intertwined particles after a sintering process. After electrodeposition, white spheres turned to a dark gray color, demonstrating the presence of silver nanoparticles and fractal silver dendrites on the surface. Spheres were characterized by SEM, FTIR, and XRD. Antimicrobial activity of the alumina-AgP spheres against E. coli, S. aureus, K. pneumoniae, and S. mutans was analyzed by turbidimetry. The specific antimicrobial activity of all the composites showed specific antibacterial effects, independently of the amount of silver deposited, probably due to the differences in the microbial cell wall structures. Therefore, antibacterial activity depends on microbiological and structural characteristics of each bacterium.

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