scholarly journals Anacyclus pyrethrum (L): Chemical Composition, Analgesic, Anti-Inflammatory, and Wound Healing Properties

Molecules ◽  
2020 ◽  
Vol 25 (22) ◽  
pp. 5469
Author(s):  
Fatima Zahra Jawhari ◽  
Abdelfattah El Moussaoui ◽  
Mohammed Bourhia ◽  
Hamada Imtara ◽  
Hamza Mechchate ◽  
...  
Keyword(s):  
Wound Healing ◽  
Chemical Composition ◽  
Butyl Ester ◽  
Well Being ◽  
Phytochemical Analysis ◽  
Traditional Medicines ◽  
The Family ◽  
Anti Inflammatory ◽  
Incision Wound ◽  
Different Parts

Background: Anacyclus pyrethrum (A. pyrethrum) is a wild species belonging to the family Asteraceae, which is used in traditional medicines. Aim of the study: This work was undertaken to study the chemical composition, analgesic, anti-inflammatory, and wound healing properties of hydroalcoholic extracts of different parts (roots, seeds, leaves, and capitula) of A. pyrethrum. Material and Methods: The phytochemical analysis of the studied extracts was conducted by GC-MS. The analgesic activity was evaluated in mice using acetic acid and formaldehyde methods. The anti-inflammatory activity was tested using the inhibitory method of edema induced in rats. The healing activity of the hydroethanolic extracts was explored by excision and incision wound healing models in rats. Results: The phytochemical analysis of the studied plant extracts affirmed the presence of interesting compounds, including some newly detected elements, such as sarcosine, N-(trifluoroacetyl)-butyl ester, levulinic acid, malonic acid, palmitic acid, morphinan-6-One, 4,5.alpha.-epoxy-3-hydroxy-17-methyl, 2,4-undecadiene-8,10-diyne-N-tyramide, and isovaleric acid. The extracts of different parts (roots, seeds, leaves, and capitula) exhibited promising anti-inflammatory, analgesic, and wound healing effects, with percentages of inhibition up to 98%, 94%, and 100%, respectively. Conclusion: This study might contribute towards the well-being of society as it provides evidence on the potential analgesic, anti-inflammatory, and wound healing properties of A. pyrethrum.

scholarly journals Chemical Composition of Cinnamomum verum Leaf and Flower Essential Oils and Analysis of Their Antibacterial, Insecticidal, and Larvicidal Properties

Molecules ◽  
2021 ◽  
Vol 26 (20) ◽  
pp. 6303
Author(s):  
Arunaksharan Narayanankutty ◽  
Krishnaprasad Kunnath ◽  
Ahmed Alfarhan ◽  
Rajakrishnan Rajagopal ◽  
Varsha Ramesh
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Essential Oils ◽  
Callosobruchus Maculatus ◽  
Sitophilus Oryzae ◽  
Microbial Pathogens ◽  
Traditional Medicines ◽  
Significant Toxicity ◽  
Leaf Essential Oil ◽  
Different Parts

Cinnamomum verum is widely used in traditional medicines, and the different parts of the plant, such as bark, leaves, and flowers, are used for essential oil production. The present study compared the chemical composition of the essential oil of C. verum extracted from the leaves and flowers. In addition, efficacy of these essential oils against the two common pests Sitophilus oryzae and Callosobruchus maculatus was also evaluated. The results indicated the presence of cinnamaldehyde, eugenol, caryophyllene, and linalool in these essential oils, however, at different concentrations. The leaf essential oil was found to be 10–20% more effective as a fumigant against both the pests. Likewise, the leaf essential oil found to repel these pests even at lower concentrations than that of flower essential oil of C. verum. Besides, these essential oils were also effective in controlling the growth of various gram positive and gram negative microbial pathogens and possibly a safeguard for human health. On contrary, both the essential oils were found to be safe for the application on grains, as indicated by their germination potentials. It was also observed that these essential oils do not cause any significant toxicity to guppy fishes, thus confirming their ecological safety for use as a biopesticide.

scholarly journals A Review on the Ethnobotanical Uses, Phytochemistry and Pharmacology Effect of Luffa cylindrica

2021 ◽  
Author(s):  
Kazeeem Akinyinka Akinwumi ◽  
Oluwole Olusoji Eleyowo ◽  
Omolara Omowunmi Oladipo
Keyword(s):  
Wound Healing ◽  
Methyl Ester ◽  
Whooping Cough ◽  
Wide Spectrum ◽  
Luffa Cylindrica ◽  
Upset Stomach ◽  
Anti Inflammatory ◽  
Ethnobotanical Uses ◽  
Black Seeds ◽  
Different Parts

Luffa cylindrica, popularly known as sponge gourd is a tropic and sub-tropical fibrous plant with fruits containing black seeds. The fruit is consumed by humans as a vegetable in many parts of Asia, while different parts of the plant are used for cosmetics and as medicine in many parts of the globe. The plant has been used in the treatment of many ailments including nose cancer, snake venom, wound healing, edema, enterobiasis, filaria, whooping cough, stomach upset, stomach pain and malaria. Many health-promoting compounds such as flavonoids (apigenin-7- glucuronide luteolin-7-O-β-D-glucuronide methyl ester, -O-feruloyl-β-D-glucose, luteolin-7-O-β-D-glucuronide methyl ester), phenolics acids (p-Coumaric, gallic, caffeic, chlorogenic), triterpenoids (oleanolic acid and echinocystic acid), saponins (Lucyoside A-M), tannins (catechin), ribosome-inactivating proteins (α- luffin), carotenoids (9 -cis neoxanthin, all-trans-lutein, all-trans-β-carotene), chlorophylls (chlorophyll a and b, pheophytin), cucurbitacin B and gypsogenin have been detected or isolated from different parts of the plants. Extracts of the plant and isolated compounds have wide spectrum pharmacological activities and have been shown to possess antiemetic, antidiabetic, antiviral, wound healing, anticancer, antipyretic, anti-inflammatory, antifungal, anti-bacteria, anthelmintic, hypoglycemic and antihyperglycemic, anti-inflammatory, antioxidant activity, and hepato-protective effects in animal models. However, further information is needed on its safety and mechanisms of action. The present article is an updated review of the ethnobotanical uses, pharmacological actions, phytochemistry, safety, and future application of Luffa cylindrica in translational medicine.

scholarly journals Chemical composition of healthy and infected leaves by Forda riccobonii and Geoica swirskii of Pistacia atlantica Desf. collected from Maaziz region in Morocco

2019 ◽  
Vol 9 (5) ◽  
pp. 382-389
Author(s):  
Hazim Harouak ◽  
Jamal Ibijbijen ◽  
Touria Zair ◽  
Laila Nassiri
Keyword(s):  
Chemical Composition ◽  
Essential Oils ◽  
Biologically Active ◽  
Phytochemical Analysis ◽  
Widespread Species ◽  
Pistacia Atlantica ◽  
Active Chemical ◽  
The Family ◽  
Traditional Pharmacopoeia ◽  
Health Field

The Atlas Pistachio, Pistacia atlantica Desf., from the family of Anacardiaceae is a widespread species in Morocco and widely present in traditional pharmacopoeia 1. This species is frequently infected by Forda riccobonii and Geoica swirskii  that are foliar galls-inducing aphids.The aim of this study was to compare the chemical composition of essential oils (EO) of the  infected and healthy leaves of Pistacia atlantica. The extraction of essential oils was performed by hydro-distillation using Clevenger, phytochemical screening was realized by revelations tests and chemical composition was identified by gas chromatography coupled with mass spectrometry (GC-MS).Phytochemical analysis showed the presence of some biologically active chemical compounds such as tannins, flavonoids, sterols and triterpenes. The infected leaves were richer in tannins than healthy ones, especially in gallic tannins.Also, the results reaveled that the EO yield of leaves with galls was higher (0.71%) than that of healthy ones (0.11%); also, the first type of leaves was predominated by α-Pinene (19.76%) followed by Terpinen-4-ol, Spathulenol and Sabinene with percentages of 11.94%, 8.90% and 7.63%, respectively. Whereas, healthy leaves were predominated by α-Amorphene (15.05%) followed by Terpinen-4-ol, Spathulenol and α-Muurolene with percentages of 7.17%, 6.46% and 6.20%, respectively.So, we arrived to conclude that infected leaves have a higher level of  monoterpenes hydrocarbon than healthy ones that contains interesting molecules useful in differentes domains, especially in the health field.

scholarly journals Caralluma europaea (Guss.) N.E.Br.: Anti-Inflammatory, Antifungal, and Antibacterial Activities against Nosocomial Antibiotic-Resistant Microbes of Chemically Characterized Fractions

Molecules ◽  
2021 ◽  
Vol 26 (3) ◽  
pp. 636
Author(s):  
Fatima Ez-Zahra Amrati ◽  
Mohammed Bourhia ◽  
Hamza Saghrouchni ◽  
Meryem Slighoua ◽  
Andriy Grafov ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Chemical Characterization ◽  
Antibacterial Activities ◽  
Antibiotic Resistant ◽  
Traditional Medicines ◽  
Gram Positive Bacteria ◽  
Antibacterial And Antifungal Activities ◽  
The Family ◽  
Anti Inflammatory ◽  
Antibacterial And Antifungal

Caralluma europaea (Guss.) N.E.Br.: (C. europaea) is a wild medicinal plant belonging to the family Apocynaceae. It is commonly used in traditional medicines for treating several diseases. The present work aims to evaluate the anti-inflammatory, antibacterial, and antifungal potentials of C. europaea fractions including hydro ethanol (ET CE), n-butanol (But CE), and polyphenol (Poly CE). The chemical composition of hydroethanol, n-butanol, and polyphenol-rich fractions from C. europaea were determined using GC-MS after silylation. The anti-inflammatory effect of hydroethanol, n-butanol, and polyphenol-rich fractions was studied by carrageenan-induced paw edema. Antibacterial and antifungal activities of hydroethanol, n-butanol, and polyphenol-rich fractions against Gram-positive bacteria, Gram-negative bacteria, and yeasts were assessed using the disc diffusion and micro-dilution assays. The findings of the chemical characterization affirmed the presence of interesting bioactive compounds in C. europaea fractions. The polyphenol-rich fraction was the best inhibitor of edema by75.68% after 6 h of treatment. The hydroethanol fraction was the most active against both bacteria and yeasts. This study contributes to society as it provides potential bioactive compounds in C. europaea extract, which may help in fighting nosocomial antibiotic-resistant microbes.

scholarly journals Euryops arabicus Promotes Healing of Excised Wounds in Rat Skin: Emphasis on Its Collagen-Enhancing, Antioxidant, and Anti-Inflammatory Activities

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Ahmed Abdel-Lateff ◽  
Ashraf B. Abdel-Naim ◽  
Walied M. Alarif ◽  
Mardi M. Algandaby ◽  
Najla A. Alburae ◽  
...  
Keyword(s):  
Wound Healing ◽  
Mrna Expression ◽  
Folk Medicine ◽  
Antioxidant Properties ◽  
Skin Wound ◽  
Tnf Α ◽  
The Family ◽  
Anti Inflammatory ◽  
Tgf Β1

Euryops arabicus Steud (E. arabicus) belongs to the family Asteraceae. It has several uses in folk medicine in the Arabian Peninsula. The current study aimed at evaluating the wound healing properties of the E. arabicus extract in rats. Primarily, E. arabicus successfully accelerated cell migration in vitro and it also showed no signs of dermal toxicity. Topical application of E. arabicus extract (5% or 20%) expedited healing of excised skin in rats. Histological examinations indicated that E. arabicus shortened epithelization period, stimulated fibroblast activity, and increased collagen deposition in wound tissues. The plant extract exerted antioxidant activity as evidenced by inhibition of GSH depletion and MDA accumulation and enhanced mRNA expression of Sod1 in wound tissues collected at the end of the experiment. Further, E. arabicus inhibited the rise of TNF-α and IL-1β in the skin wound region. The anti-inflammatory was confirmed by the observed down regulation of Ptgs2, Nos2, IL-6, and NF-κB mRNA expression. In addition, the extract enhanced the expression of TGF-β1 and HIF-1α in wounded skin tissues as indicated immunohistochemically. Conclusively, E. arabicus expedites excision wound healing in rats. Collagen-enhancing, anti-inflammatory, and antioxidant properties mediate the observed wound healing activity. These findings might contribute to our understanding of the ethnobotanical use of E. arabicus in wounds.

scholarly journals Formulation and Evaluation of Nagarmotha Hair Oil

2021 ◽  
Vol 9 (12) ◽  
pp. 1107-1113
Author(s):  
Miss. Patil Shivani Navnath
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Pharmacological Activity ◽  
Cyperus Rotundus ◽  
Chemical Components ◽  
Therapeutic Action ◽  
Extensive Review ◽  
The Family ◽  
Anti Inflammatory ◽  
Major Chemical

Abstract: The Presenace study investigation oil isolation form cyperus rotundus and the chemical composition of essential oil of root's of Cyprus rotundus.In india it's commonly known as nagarmotha.and it belongs to the family cyperacea.the major chemical components of this herb are essential oils.flavonoids, terpenoids, sesauiterpenes, cyproten, cyperene, aselinene, rotundene, valencene, cyperol, gurjunene, transcalamenenene, cad'Alene, cyperoutundone, mustskone, isocyperol, acyperone etc. Reserch studies have shown that it possesses various Pharmacological activity Such as diuretic,carmenative emmenagogue, anthelmintic, analgesic, anti-inflammatory, anti-dysentery, anti-rheumatic activities.an extensive review of the ancient traditional literature and madern research revealead that the drug has numerous therapeutic action. Several of which have been established scientifically, which may help the reserchers to set their minds for approaching the utility efficiency and potency of nagarmotha. Keywords: cyperus rotundus, cyprotene flavanoids nagarmotha.

scholarly journals A REVIEW ON PHYTOCHEMISTRY AND PHARMACOLOGY OF CALYCOPTERIS FLORIBUNDA ROXB. LAM

2020 ◽  
pp. 1-8
Author(s):  
C. AZHAGUMEENA ◽  
P. RAJASRI BHARATHI
Keyword(s):  
Wound Healing ◽  
Medicinal Plant ◽  
East Asian ◽  
Flavonoid Compound ◽  
Asian Countries ◽  
The Family ◽  
Anti Inflammatory ◽  
Pharmacological Potential ◽  
Malarial Fever

The medicinal plant Calycopteris floribunda Roxb. Lam. commonly known as “Ukshi” belongs to the family Combretaceae. Calycopteris floribunda is a large evergreen climbing shrub native of Bangladesh and India. It is widely distributed in the central and southern parts of India and also found in south-east Asian countries. The branches store abundant water for its own purpose as well to quench the thirst of the forest dwellers. Hence the forest habitants are referring this plant as a lifesaver. Calycopteris floribunda finds a place in traditional Asian medicinal systems, including Ayurveda, Folk and Unani. The anti-inflammatory flavonoid compound calycopterin is present in the leaves of the plant. In Ayurveda this plant is used to treat for leprosy, malarial fever, dysentery, ulcers, vomiting, wound healing and cytotoxic. It is hepatoprotective, antimicrobial, antiviral and used for numerous ailments. A review on the medicinal plant Calycopteris floribunda was done in the period from 1934 to 2020. Here, we are focusing on the isolation, phytochemical constitution and pharmacological potential of Calycopteris floribunda plant.

scholarly journals An Overview of Golden Spice’s (Turmeric) Medicinal Properties for Future Development Potential

2021 ◽  
Author(s):  
Zarini Ismail ◽  
Nur Ain Nabila Mazuki
Keyword(s):  
Therapeutic Agent ◽  
Curcuma Longa ◽  
Alternative Source ◽  
Traditional Medicines ◽  
The Family ◽  
The World ◽  
Medicinal Properties ◽  
Therapeutic Properties ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Traditional medicines that are derived mainly from herbaceous plants are widely used for years in many regions of the world. Currently, the world is facing the emergence of resistant microorganisms due to the overuse and misuse of antibiotics and the lack of new drug development. In consequence, the discovery of natural phytochemicals that are safe, cheap, non-toxic, and readily available would be an acceptable alternative source. Turmeric, scientifically known as Curcuma longa, in the family of Zingiberaceae (ginger) is well known for its diverse therapeutic properties. The medicinal properties of turmeric include antioxidant, anti-inflammatory, anti-microbial, anti-carcinogenic, cardioprotective, gastroprotective, hepatoprotective, and many more. Numerous studies have shown that curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione), which is the most active compound of turmeric, plays a significant role as a therapeutic agent. The present article provides a brief overview of the plethora of research regarding the medicinal properties of golden spice (turmeric), specifically of curcumin's role in the treatment of various illnesses. Interestingly, turmeric might play a role in protecting COVID-19 patients against the development of lung injury caused by cytokine storms. Hence, this warrants further scientific research to monitor the anti-inflammatory effect of turmeric on SARS-CoV-2.

scholarly journals Analytical Profile of an Unparalleled Drug Tinospora crispa W.R.T Guduchi

2021 ◽  
pp. 195-203
Author(s):  
S. Lekshmipriya ◽  
M. R. Pandya ◽  
Bijal Prajapati
Keyword(s):  
Research Study ◽  
Pharmacological Activities ◽  
Important Species ◽  
Traditional Medicines ◽  
Flavone Glycosides ◽  
Therapeutic Benefits ◽  
Research Article ◽  
The Family ◽  
Current Article ◽  
Anti Inflammatory

Introduction: Guduchi is a highly potential drug which is mentioned in Ayurveda classics. The clinical utility of this drug is widely known. The Tinospora species are wrapped under the broad spectrum Guduchiin the Ayurveda classics. Tinospora is one of the important genera of the family, consisting of about 15 species. Some medicinally important species includes T. cordifolia, T. malabarica, T. tomentosa, T. crispa, T. uliginosa, T. crispaetc. In the current article the drug Tinospora crispa is considered in detail.Tinospora crispa is used irrationally by the society owing to its various therapeutic benefits. Tinospora crispa (L.) Hook. f. & Thomson (Menispermaceae), found in the rainforests or mixed deciduous forests in Asia and Africa, is used in traditional medicines to treat numerous health conditions. Materials & Methods: A detailed review of the drug has been carried out through the available literature. After considering the review the analytical profiling of the drug has been done.The phytochemical analyses review of T. crispa revealed the presence of alkaloids, flavonoids, and flavone glycosides, triterpenes, diterpenes and diterpene glycosides, cis clerodane-type furanoditerpenoids, lactones, sterols, lignans, and nucleosides. The literary review showed that the crude extracts and isolated compounds of T. crispa possessed a broad range of pharmacological activities such as anti-inflammatory, antioxidant, immunomodulatory, cytotoxic, antimalarial, cardioprotective, and anti-diabetic activities.So, in the current research study a sincere attempt has been made to study regarding the drug Tinospora crispa through its analytical profile. Results: Through this research article able to make out the available literature and the analytical profile of the drug Tinospora crispa. Discussion: The current analytical profile reveals the presence of alkaloids, tannins, flavonoids, saponins etc which directly connects to the various activities like Anti-pyretic, Anti- inflammatory, Antioxidant etc of the drug Tinospora crispa. Conclusion: The current research study points towards the review of the drug and the analytical profile which is beneficial to carry out the next phase of research studies in connection with this drug Tinospora crispa.

Phytochemical Study and Screening of Antioxidant, Anti-inflammatory Typhonium Flagelliforme

2021 ◽  
pp. 2686-2690
Author(s):  
Nitin A. Mirgane ◽  
Arun Chandore ◽  
Vitthal Shivankar ◽  
Yashwant Gaikwad ◽  
Gurumeet C. Wadhawa
Keyword(s):  
Biological Properties ◽  
Plant Part ◽  
Inflammatory Activity ◽  
Phytochemical Analysis ◽  
Rare Plant ◽  
Active Constituent ◽  
Phytochemical Study ◽  
The Family ◽  
Stem Extract ◽  
Anti Inflammatory

Typhonium flagelliforme from the family Araceae is very rare plant. It is very good curative and work against various illness and infections. The plant part has large importance in Ayurveda. In this study we use stem and leaves used for phytochemical analysis and their biological properties such as Antioxidant and Anti-inflammatory activity. Known Protocol for the phytochemical analysis, while antioxidant and anti-inflammatory activity was determined using known methods. Both the leaves and stem extract show presence of various important active constituent and shows better activity against the free radicals or antioxidant activity or they can show the anti-inflammatory activity.

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