scholarly journals Pengaruh Menstruasi terhadap Akne Vulgaris

e-CliniC ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 305
Author(s):  
Lusiane M Hartono ◽  
Marlyn G Kapantow ◽  
Tara S Kairupan

Abstract: Acne vulgaris is a common inflammatory condition of pilosebaceous follicles that affects 85-100% of the human population. Patients usually complain of the appearance of acne vulagaris on the predilection areas such as face and neck (99%), back (60%), chest, shoulders and upper arms (15%). One of the factors that influence or trigger acne vulgaris is hormonal factor. During menstruation there is an increase and hormonal changes that can trigger acne. This study was aimed to determine the effect of menstruation on acne vulgaris. This was a literature review study using three databases named PubMed, ClinicalKey and Google Scholar. Keywords used were “Menstruasi” DAN “Akne Vulgaris” (Indonesia), and “Menstruation” AND “Acne Vulgaris” (English). In this study, there were 12 literatures that match the inclusion and exclusion criteria. The result was dominated by samples stating that there was a connection between menstruation and the appearance of acne vulgaris. The effect of hormonal instability during menstruation was one of the causes of acne vulgaris in women, which showed the effect of menstruation on the emergence of acne vulgaris, mostly during pre-menstruation. In conclusion, menstruation influences the occurrence and the severity of acne vulgaris.Keywords: menstruation, acne vulgaris  Abstrak: Akne vulgaris (AV) atau jerawat merupakan suatu kondisi inflamasi umum pada folikel pilosebasea yang dialami oleh 85-100% populasi manusia. Penderita biasanya mengeluh kemunculan AV pada predileksi wajah dan leher (99%), punggung (60%), dada (15%) bahu, dan lengan bagian atas. Faktor yang memengaruhi atau mencetuskan akne vulgaris salah satunya ialah faktor hormonal. Saat menstruasi terjadi peningkatan dan perubahan hormon yang dapat memicu akne. Penelitian ini bertujuan untuk mengetahui pengaruh menstruasi terhadap akne vulgaris. Penelitian ini berbentuk literature review. Pencarian data menggunakan tiga database yaitu PubMed, ClinicalKey dan Google Scholar. Kata kunci yang digunakan “Menstruasi” DAN “Akne Vulgaris” (Bahasa Indonesia) serta “Menstuation” AND “Acne Vulgaris” (Bahasa Inggris). Pada penelitian ini didapatkan 12 literatur yang sesuai dengan kriteria inklusi dan ekslusi. Hasil penelitian didominasi oleh sampel yang menyatakan adanya pengaruh antara menstruasi dengan munculnya AV. Pengaruh ketidakstabilan hormon (estrogen dan progesteron) saat menstruasi merupakan salah satu penyebab munculnya akne vulgaris pada perempuan yang menunjukan adanya pengaruh dari menstruasi terhadap kemunculan AV, terlebih pada saat pre-menstruasi. Simpulan penelitian ini ialah menstruasi memengaruhi kemunculan dan keparahan akne vulgaris.Kata kunci: menstruasi, akne vulgaris

e-CliniC ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 299
Author(s):  
Deshinta Dumgair ◽  
Herry EJ Pandeleke ◽  
Marlyn G Kapantow

Abstract: Acne vulgaris is a chronic pilosebaceous follicle inflammation andi its highest prevalence is on 16-17-year-olds. Factors influencing or triggering acne vulgaris are sebum, genetics, hormones, diet, stress, and cosmetics. Inadequate and unqualified sleep may disrupt physiological and psychological balances, and is estimated to increase androgen hormone activities. This study was aimed to obtain the effect of sleep quality on acne vulgaris incidence. This was a literature review using three databases, as follows: PubMed, ClinicalKey, and Google Scholar. Keywords used were “Kualitas Tidur” DAN “Akne Vulgaris” (Indonesian), and “Sleep quality” AND “Acne Vulgaris” (English). The results obtained 10 literature matching the inclusion and exclusion criteria. The number of samples suffered from acne vulgaris with poor sleep quality was higher than of samples with good sleep quality. There were more male samples than female samples in all literatures in the study. In conclusion, poor sleep quality could trigger and contribute in the development of acne vulgaris.Keywords: sleep quality, acne vulgaris, severity degree  Abstrak: Akne vulgaris merupakan peradangan kronis folikel polisebasea dengan prevalensi tertinggi pada usia 16-17 tahun. Faktor yang memengaruhi atau mencetuskan akne vulgaris yaitu sebum, genetik, hormon, diet, stres, dan kosmetik. Tidur yang tidak adekuat dan berkualitas dapat mengakibatkan gangguan keseimbangan fisiologis, dan psikologis, serta diperkirakan dapat menyebabkan aktivitas hormon androgen meningkat. Penelitian ini bertujuan untuk mengetahui pengaruh kualitas tidur terhadap kejadian akne vulgaris. Jenis penelitian ialah literature review dengan pencarian data menggunakan tiga database yaitu PubMed, ClinicalKey dan Google Scholar. Kata kunci yang digunakan yaitu “Kualitas Tidur” DAN “Akne Vulgaris” (Bahasa Indonesia), serta “Sleep quality” AND “Acne Vulgaris” (Bahasa Inggris). Hasil penelitian mendapatkan 10 literatur yang sesuai dengan kriteria inklusi dan ekslusi. Sampel yang memiliki kualitas tidur buruk dan menderita akne vulgaris lebih banyak daripada sampel yang memiliki kualitas tidur baik dan menderita akne vulgaris. Derajat keparahan akne vulgaris paling banyak derajat sedang. Total sampel laki-laki lebih banyak dibandingkan dengan perempuan pada semua literatur yang digunakan dalam penelitian. Simpulan penelitian ini ialah kualitas tidur yang buruk dapat mengakibatkan timbulnya akne vulgaris dan juga menjadi salah satu faktor yang berkontribusi dalam perkembangan akne vulgaris.Kata kunci: kualitas tidur, akne vulgaris, tingkat keparahan


2021 ◽  
Vol 2 (2) ◽  
Author(s):  
Julian Juanito ◽  
Wenny P. Supit ◽  
Laya M. Rares

Abstract: High intraocular pressure (IOP) is one of the risk factors of glaucoma or worsening of its prognosis. There are a lot of external factors that can affect IOP inter alia exercise, as well as some food and drinks. One of the drinks that could affect IOP is coffee that contains caffeine. This study was aimed to evaluate whether caffeine had an effect on IOP. This was a literature review study using 4 data bases, as follows: Clinical Key, Pub-med, Google Scholar, and Science Direct. The keywords were Caffeine OR Coffee OR Tea AND IOP OR Intraocular Pressure. Based on inclusion and exclusion criteria, 10 literatures were selected. The results showed that some literatures reported an increase in IOP after caffeine consumption, the others reported a decrease in IOP, meanwhile some others did not find any change of IOP. In conclusion, the effect of caffeine on IOP was acute. People who had high intensity of caffeine consumption had a more significant increase in IOP after consuming caffeine.Keywords: caffeine, intraocular pressure (IOP)  Abstrak: Peningkatan tekanan intraokular (TIO) merupakan salah satu faktor risiko untuk terjadinya glaukoma atau memperburuk prognosis glaukoma. Terdapat banyak faktor eksternal yang dapat memengaruhi TIO, antara lain olahraga, minuman, dan makanan. Salah satu minuman yang dapat memengaruhi TIO ialah kopi yang mengandung kafein. Penelitian ini bertujuan untuk mengetahui adanya pengaruh kafein pada tekanan intraokular. Jenis penelitian ialah literature review. Pencarian data menggunakan empat database yaitu Clinical key, PubMed, Google scholar, dan Science direct. Kata kunci yang digunakan yaitu Caffeine OR Coffee OR Tea AND IOP OR Intraocular Pressure. Seleksi data berdasarkan kriteria inklusi dan ekslusi mendapatkan 10 literatur. Hasil kajian mendapatkan bahwa beberapa penelitian melaporkan adanya peningkatan TIO setelah konsumsi kafein, penelitian lain melaporkan penurunan TIO, dan terdapat pula penelitian yang tidak menemukan perubahan apapun. Simpulan penelitian ini ialah pengaruh kafein pada TIO hanya berlangsung akut. Individu yang memiliki intensitas konsumsi kafein lebih tinggi menunjukkan peningkatan TIO yang lebih nyata setelah mengonsumsi kafein.Kata kunci: kafein, tekanan intraokular (TIO) 


e-CliniC ◽  
2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Andreas V. Pusung ◽  
Pieter L. Suling ◽  
Nurdjannah J. Niode

Abstract: Pityriasis versicolor is a chronic mild superficial fungal infection of the skin due to lipophilic fungi Malassezia. It commonly affects the face, neck, abdomen, proximal extremities, axilla, groin, and genitalia. The occurrence of this disease is not influenced by sex, albeit, age influences its incidence since it is more common in adolescents and young adults.Therefore, an effective, safe, and affordable treatment should be considered. The first-line therapy for pity-riasis versicolor is topical treatment, classified into specific and non-specific antifungal agents. This study was aimed to determine the efficacy of topical treatment in pityriasis versicolor. This was a literature review study using three databases, namely PubMed, ClinicalKey, and Google Scholar and the keywords of "topical treatment AND pityriasis versicolor". The results obtained 10 literatures that fulfilled the inclusion and exclusion criteria. Theseliteratures discussed about the efficacy of topical treatment in patients with pityriasis versicolor based on clinical and mycological cure rate and the highest percentage was more than 80% in each study. In conclusion, topical treatment was effective for pityriasis versicolor.Keywords: topical treatment, pityriasis versicolor Abstrak: Pitiriasis versikolor adalah penyakit jamur superfisial ringan akibat infeksi kulit kronis oleh jamur lipofilik genus Malassezia. Infeksi ini biasanya ditemukan pada wajah, leher, perut, ektremitas proksimal, aksila, lipat paha, dan genitalia. Kejadian penyakit ini tidak dipengaruhi oleh jenis kelamin, tetapi dapat dipengaruhi oleh usia, yaitu lebih banyak terjadi pada remaja dan dewasa muda. Pengobatan topikal merupakan terapi lini pertama untuk pitiriasis versikolor dan dibagi menjadi agen antijamur nonspesifik dan agen antijamur spesifik. Penelitian ini bertujuan untuk mengetahui efektivitas pengobatan topikal pada pitiriasis versikolor. Jenis penelitian ialah literature review dengan pencarian data menggunakan tiga database yaitu PubMed, ClinicalKey, dan Google Scholar. Kata kunci yang digunakan yaitu “topical treatment AND pityriasis versicolor”.Hasil seleksi berdasarkan kriteria inklusi dan eksklusi mendapatkan 10 literatur. Kasjian literatur penelitian menunjukkan efektivitas penggunaan pengobatan topikal pada pitiriasis versikolor berdasarkan penyembuhan klinis maupun penyembuhan mikologis dengan persentase tertinggi mencapai angka >80% pada masing-masing literatur. Simpulan penelitian ini ialah pengobatan topikal pada pitiriasis versikolor terbukti efektif.Kata kunci: pengobatan topikal, pitiriasis versikolor


e-CliniC ◽  
2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Muhammad F. H. Putra ◽  
Vonny N. Tubagus ◽  
Yohanna P. M. Mamesah

Abstract: COVID-19 is an infectious disease caused by SARS-CoV-2 virus that has become a health problem worldwide, including Indonesia. The SARS-CoV-2 was identified in the early 2020. For current diagnostic procedures, RT-PCR is considered as the gold standard in COVID-19 detection. However, there is another alternative method which is the chest CT-scan that can supports the diagnosis of COVID-19 faster. This study was aimed to determine the sensitivity of the CT scan in COVID-19 patients. This was a literature review study using three databases, as follows: Pubmed, ClinicalKey, and Google Scholar. The keywords used were sensitivity AND CT scan AND COVID-19. After being selected based on inclusion and exclusion criteria, 10 literatures would be discussed. The results showed that the sensitivity of the CT scan among COVID-19 patients was quite good and had a sensitivity percentage ranging 70-90%. In comparison with the RT-PCR examination, the CT scan results are quite good. CT scan has a high sensitivity to COVID-19 and has a better result compared to the RT-PCR test.Keywords: sensitivity of test, CT scan, COVID-19 Abstrak: COVID-19 merupakan penyakit infeksi yang disebabkan oleh SARS-CoV-2 yang telah menjadi masalah kesehatan di dunia, termasuk di Indonesia. SARS-CoV-2 baru teridentifikasi pada awal tahun 2020. Untuk prosedur diagnostik saat ini, RT-PCR dianggap sebagai standar baku emas dalam deteksi COVID-19. Namun terdapat metode lain yaitu pemeriksaan CT scan toraks yang merupakan tes alternatif cepat untuk dilakukan dan dapat membantu menegakkan diagnosis COVID-19. Penelitian ini bertujuan untuk mengetahui sensitivitas dari pemeriksaan CT scan pada COVID-19. Jenis penelitian ialah literature review dengan pencarian data menggunakan tiga database yaitu Pubmed, ClinicalKey, dan Google Scholar. Kata kunci yang digunakan yaitu sensitivity AND CT scan AND COVID-19. Setelah diseleksi berdasarkan kriteria inklusi dan eksklusi, didapatkan 10 literatur yang dibahas dalam penelitian ini. Hasil penelitian menunjukkan bahwa sensitivitas pemeriksaan CT scan pada COVID-19 cukup baik dan memiliki rentang persentase sensitivitas 70-90%. Pada perbandingan dengan pemeriksaan RT-PCR didapatkan hasil yang cukup baik untuk pemeriksaan CT scan. Pemeriksaan CT Scan memiliki nilai sensitivitas yang cukup tinggi pada COVID-19 dan lebih baik dibandingkan RT-PCR.Kata kunci: sensitivitas tes, CT scan toraks, COVID-19


e-GIGI ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 250
Author(s):  
Geraldo Y. Aruperes ◽  
Damajanty H. C. Pangemanan ◽  
Christy N. Mintjelungan

Abstract: Herbal plants in Indonesia have been widely used as ingredients in traditional medicine; one of them is binahong plant (Anredera cordifolia Steenis). Binahong has roots, tubers, stems, flowers, and leaves that contain active compounds, namely flavonoids, alkaloids, terpenoids, and saponins. The active compounds of flavonoids can act directly as antibiotics by interfering with the function of microorganisms such as bacteria and viruses. Binahong also contains active antimicrobials that can be used to prevent bacterial growth. This study was aimed to determine the inhibition effect of binahong leaf extract (Anredera cardifolia Ssteenis) against the growth of Streptococcus mutans. This was a literature review study by searching databases of Google Scholar and Pubmed. The keywords used were Binahong leaf (Anredera Cordifolia Steenis), Streptococcus mutans. After being selected based on the inclusion and exclusion criteria, 10 experimental literatures were obtained. The results showed that as many as 10 literatures stated that binahong leaf extract could inhibit the growth of Streptococcus mutans depending on the amount of binahong leaf extract given. In conclusion, binahong leaf extract has the ability to inhibit the growth of Streptococcus mutans which depends on the amount of the leaf extract.Keywords: binahong leaves (Anredera cordifolia Steenis); Streptococcus mutans Abstrak: Tanaman herbal di Indonesia telah banyak digunakan sebagai bahan obat tradisional, salah satunya ialah tanaman binahong (Anredera cordifolia Steenis). Binahong memiliki akar, umbi, batang, bunga, daun yang mengandung senyawa aktif yaitu flavonoid, alkanoid, terpenoid dan saponin. Senyawa aktif flavonoid dapat berperan langsung sebagai antibiotik dengan menggangu fungsi mikroorganisme seperti bakteri dan virus. Binahong juga mengandung antimikroba yang aktif sehingga dapat digunakan dalam mencegah pertumbuhan bakteri. Penelitian ini bertujuan untuk mengetahui daya hambat ekstrak daun binahong (Anredera cardifolia Steenis) terhadap pertumbuhan bakteri Streptoccocus mutans. Jenis penelitian ini suatu literature review. Pencarian data menggunakan database Google Scholar dan Pubmed dengan kata kunci yaitu daun Binahong (Anredera Cordifolia Steenis), Streptococcus mutans. Setelah diseleksi berdasarkan kriteria inklusi dan eksklusi didapatkan 10 literatur eksperimental yang digunakan dalam penelitian ini. Hasil penelitian memperlihatkan bahwa ke 10 literatur tersebut menyatakan ekstrak daun binahong memiliki daya hambat terhadap pertumbuhan bakteri Streptococcus mutans, dan daya hambatnya tergantung dari banyaknya ekstrak daun binahong yang diberikan. Simpulan penelitian ini ialah ekstrak daun binahong mampu menghambat pertumbuhan bakteri Streptococcus mutans yang dipengaruhi oleh banyaknya ekstrak daun tersebut.Kata kunci: daun binahong (Anredera cordifolia Steenis); Streptococcus mutans


e-GIGI ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 347
Author(s):  
Glady A. Tetelepta ◽  
Michael A. Leman ◽  
Paulina N. Gunawan

Abstract: Maxillofacial trauma can be caused by various external and internal factors. The intervention to prevent the COVID-19 pandemic has caused changes in community social activities that contributes to the factors causing maxillofacial trauma during the pandemic. This study was aimed to obtain the factors that caused maxillofacial trauma before and during the COVID-19 pandemic. This was a literature review study using three databases, namely Google Scholar, Pubmed, and ClinicalKey, and the keywords "maxillofacial trauma", "etiology factors", and "COVID-19". The literatures were selected by using inclusion and exclusion criteria. A critical assessment was carried out and 11 literatures were obtained consisting of retrospective and cross-sectional studies. The results showed that the factors causing maxillofacial trauma in the period of before and during the pandemic belonged of three categories, as follows: falls, accidents, and violence. They consisted in detail of fall, traffic accident, sports injurie, industrial accident, suicide attempt, interpersonal violence, domestic violence. and animal-bite wound. In conclusion, fall is the most dominant etiology factor before and during the COVID-19 pandemic. Moreover, there is a difference in the factors causing maxillofacial trauma before and during the COVID-19 pandemic which is attempted suicide.Keywords: maxillofacial trauma; etiology; COVID-19 pandemic Abstrak: Trauma maksilofasial dapat disebabkan oleh berbagai faktor eksternal maupun internal. Adanya intervensi pencegahan pandemi COVID-19 menyebabkan perubahan aktifitas sosial masyarakat yang berkontribusi dalam berubahnya faktor penyebab trauma maksilofasial pada saat pandemi. Penelitian ini bertujuan untuk melihat faktor penyebab trauma maksilofasial pada masa sebelum dan saat pandemi COVID-19. Jenis penelitian ialah suatu literature review. Pencarian data melalui tiga database yaitu Google Scholar, Pubmed dan ClinicalKey menggunakan kata kunci trauma maksilofasial, faktor penyebab, dan COVID-19. Literatur diseleksi menggunakan kriteria inklusi dan eksklusi, dilakukan penilaian kelayakan dan diperoleh 11 literatur dengan desain studi retrospektif dan potong lintang. Hasil penelitian mendapatkan factor-faktor penyebab trauma maksilofasial pada masa sebelum dan saat pandemi tergolong atas tiga kategori yaitu: jatuh, kecelakaan, dan kekerasan, yang secara detil terdiri atas jatuh, kecelakaan lalu lintas, cedera olahraga, kecelakaan industri, percobaan bunuh diri, kekerasan interpersonal, kekerasan dalam rumah tangga, dan luka gigitan hewan. Simpulan penelitian ini ialah jatuh merupakan faktor penyebab trauma maksilofasial paling dominan pada masa sebelum dan saat pandemi COVID-19. Perbedaan faktor penyebab trauma maksilofasial pada masa sebelum dan saat pandemi COVID-19 yaitu percobaan bunuh diri.Kata kunci: trauma maksilofasial; etiologi; pandemi COVID-19


2021 ◽  
Vol 1 ◽  
pp. 464-469
Author(s):  
Kiki Utari ◽  
R Ratnawati

AbstractPregnant women are very susceptible to anemia due to lack of food reserves and before pregnancy they were already anemic. Pregnant women need more iron intake than before pregnancy. Problems in pregnant women are problems in pregnancy that can cause anemia. This literature review aims to determine the description of the incidence of anemia in pregnant women from various articles. This study uses a descriptive method with a literature review approach. Search articles through PubMed and Google Scholar according to keywords and then analyzed according to inclusion and exclusion criteria and found 5 articles and reviewed using the Joanna Instrument (JBI). The description of the incidence of anemia in pregnant women showed anemia as many as 258 respondents (35.3%) and those who experienced anemia were not as many as 472 respondents (64.7%). In this literature review, it was concluded that most pregnant women did not experience anemia.Keywords: Anemia, Pregnant Women AbstrakIbu hamil sangat rentan mengalami anemia karena cadangan makanan kurang dan pada saat sebelum hamil sudah mengalami anemia. Ibu hamil membutuhkan asupan zat besi yang lebih banyak dibandingkan saat sebelum hamil. Permasalahan pada ibu hamil adalah masalah – masalah dalam kehamilan yang dapat menimbulkan anemia. Literatur Review ini bertujuan untuk mengetahui Gambaran Kejadian Anemia Pada Ibu Hamil dari berbagai artikel. Penelitian ini menggunakan metode deskriptif dengan pendekatan literature review. Pencarian artikel melalui PubMed dan Google Scholar sesuai dengan kata kunci kemudian dianalisa sesuai dengan keriteria inklusi dan ekslusi dan ditemukan 5 artikel dan di review menggunakan Instrument Joanna (JBI). Gambaran kejadian Anemia pada ibu hamil didapatkan hasil anemia sebanyak 258 responden (35,3%) dan yang mengalami tidak anemia sebanyak 472 responden (64,7%). Dalam penelitian literature review ini disimpulkan bahwa sebagian besar ibu hamil tidak mengalami anemia.Kata kunci : Anemia, Ibu Hamil


2021 ◽  
Vol 20 (2) ◽  
Author(s):  
Prima Dewi Novalia ◽  
Lina Handayani

At the end of 2019, the world was shocked by the new virus called the corona virus (COVID-19), this virus was first discovered in the Wuhan area, China. COVID-19 is an infectious disease that attacks the respiratory tract. Humans exposed to this virus usually experience mild to severe symptoms. The purpose of this literature study is to discuss how the 3M health protocols application . the method us the literature review. The literature consists of journals with a travel year from 2011 to 2021. Literature collection is done through google scholar using the keywords “3M health protocol”, “COVID-19 pandemic”, and “community”. The results of the literature search were 73 articles that were relevant to the keywords, as many as 60 articles were excluded because they were not relevant to the author’s criteria. Total 13 articles using inclusion and exclusion criteria were obtained 5 articles with good quality. Review results show that most people have not implemented 3M health protocols properly and correctly, this is one of the causes of the increase in COVID-19 cases.


2021 ◽  
Vol 1 ◽  
pp. 1103-1110
Author(s):  
Didi Rethodi ◽  
Dian Kartikasari

AbstractAsthma causes narrowing of the airways, which leads to various symptoms such as whezzing, coughing, and shortness of breath (dyspnea) in sufferers. Patients with asthma often complain of experiencing sudden shortness of breath, difficulty breathing, and pain when taking a breath. These conditions can causes the patient to become stressed, anxious and the breathing pattern in no longer effective. As a result, the prognosis of disease is poor. The purpose of this literature review study was to picture the frequency of breathing in asthma patients.This literature review highlighted five articles searched from 2011-2021 throught Garba Garuda and Google Scholar. The obtained articles were apprassied using the JBI (Joanna Briggs Institute) instrument before being analyzed. This study revealed that the respiratory rate in patients with asthma increases over 20x/minutes.The conclusion from this literature review is that patients with asthma have tachypnea. This literature review may be used as a reference for hospitals, educational institutions, and other researchers to determine appropriate nursing interventions for asthma patients.Keywords:Asthma; respiratoryrate. AbstrakPenyakit asma dapat menyebabkan penyempitan pada saluran napas dan hal ini dapat menimbulkan gejala seperti mengi, batuk, dan sesak napas (dyspnea) pada penderitanya. Keluhan pasien asma yaitu sering mengalami sesak napas yang dating secara mendadak, sulit untuk bernafas, nyeri saat menarik napas. Hal ini dapat menyebabkan pasien menjadi stress, cemas dan pola napas tidak lagi efektif dan prognosis penyakitnya menjadi buruk. Tujuan dari penelitian literature review ini adalah untuk mengetahui Gambaran Frekuensi Napas Pada Pasien Asma. Metode penelitian menggunakan metode deskriptif dengan pengumpulan data literature review. Pencarian artikel dari tahun 2011-2021 melalui penelusuran Garba Garuda, dan Google Shcolar dengan kriteria inklusi populasi pasien asma dewasa, tahun artikel 2011-2021, penelitian kuantitatif. Hasil pencarian yang didapatkan berupa full text dan pdf, kemudian direview dengan menggunakan instrument JBI (Joanna Briggs Institute), didapatkan 5 artikel dari tahun 2012-2021, diekstraksi kemudian dibahas dan disimpulkan .Hasil penelitian literature review dari 5 atikel menunjukkan bahwa frekuensi napas pada pasien dengan kejadian asma mengalami peningkatan pernafasan >20x/menit. Simpulan dari literature review ini yaitu pasien dengan kejadian asma mengalami peningkatan frekuensi pernapasan. Penelitian literature review ini diharapkan dapat menjadi refrensi bagi pihak rumah sakit, institusi pendidikan maupun penelitilainnya sebagai pertimbangan untuk menentukan intervensi keperawatan yang tepat bagi pasien asma.Kata kunci : Asma, Respirasi


2021 ◽  
Vol 3 (1) ◽  
pp. 61
Author(s):  
Christesa Y. Palawe ◽  
Carla F. Kairupan ◽  
Poppy M. Lintong

Abstract: Medicinal plant that contain antioxidants is an alternative therapeutic option for liver disorders. This study was aimed to review the hepatoprotective effects of medicinal plants. This was a literature review study using PubMed, Google Scholar and Clinical Key. The results showed 10 hepatoprotective medicinal plants, as follows:  soursop leaves, yellow bamboo shoots, moringa leaves, green betel leaves, libo fruit, kenikir, neem leaves, bitter bean seeds, black cumin, and solo garlic. All of them showed hepatoprotective activities based on the results of the tests, using biochemical and histopathological parameters. Soursop leaves could increase SOD level and reduce MDA level; yellow bamboo shoots were demonstrated to maintain SGPT activities and bilirubin level; moringa leaves have been associated with the reduction of MDA, SGOT, and SGPT levels; green betel leaves were able to reduce SGOT and SGPT levels and improve liver centrolobular necrosis; libo fruit was able to lower SGPT level; kenikir and bitter bean seeds were shown to reduce SGOT and SGPT levels; neem leaves were associated with the reduction of ALT level and protection against liver cell damage; black cumin was found to reduce fat degeneration; solo garlic could reduce MDA, SGPT, and SGOT levels, and maintain SOD level. In conclusion, the 10 hepatoprotective medicinal plants have the ability to increase SOD levels, reduce SGOT, SGPT and MDA levels, maintain bilirubin levels, regenerate centrilobular necrosis of the liver, and reduce fat degeneration of the liver. Solo garlic shows the largest amount of hepatoprotective activities, followed by yellow bamboo shoots, green betel leaves and libo fruit.Keywords: medicinal plants, hepatoprotector effect  Abstrak: Pengobatan menggunakan tanaman obat yang mengandung antioksidan merupakan pilihan terapi alternatif untuk gangguan pada hati. Penelitian ini bertujuan untuk menelaah efek hepatoprotektif tanaman obat. Jenis penelitian ialah literature review dengan menggunakan PubMed, Google Scholar dan Clinical Key. Hasil penelitian mendapatkan 10 tanaman obat hepatoprotektor yaitu daun sirsak, rebung bambu kuning, daun kelor, daun sirih hijau, buah libo, kenikir, daun mimba, biji petai, jintan hitam, dan bawang lanang. Tanaman-tanaman obat tersebut memiliki aktivitas hepatoprotektif berdasarkan pengujian dengan parameter biokimia dan histopatologi. Daun sirsak dapat meningkatkan kadar SOD dan menurunkan kadar MDA; rebung bambu kuning dapat mempertahankan aktivitas SGPT dan kadar bilirubin; daun kelor menurunkan kadar MDA, SGOT, dan SGPT; daun sirih hijau menurunkan kadar SGOT dan SGPT, serta memperbaiki nekrosis sentrolobuler hati; buah libo menurunkan kadar SGPT; kenikir dan biji petai menurunkan kadar SGOT dan SGPT; daun mimba menurunkan kadar SGPT dan memiliki daya proteksi terhadap kerusakan sel hati; jintan hitam dapat mengurangi degenerasi lemak; bawang lanang menekan peningkatan kadar MDA, SGPT, SGOT dan mempertahankan kadar SOD. Simpulan penelitian ini Kesepuluh tanaman obat hepatoprotektor tersebut memiliki kemampuan dalam meningkatkan kadar SOD, menurunkan kadar SGOT, SGPT dan MDA, mempertahankan kadar bilirubin, memperbaiki nekrosis sentrolobuler hati, dan mengurangi degenerasi lemak hati. Bawang lanang menunjukkan aktivitas hepatoprotektor terbesar, diikuti rebung bambu kuning, daun sirih hijau, dan buah libo.Kata kunci: tanaman obat, efek hepatoprotektor


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