Administration of Creatine Monohydrate® increased the estrogen levels but have no effect on testosterone levels in male albino rats (rattus norvegicus) with moderate physical activity

Background: Our laboratory assessment indicated that the Creatine Monohydrate® supplement contains phytoestrogen and phytoprogesteron. This study was aimed to prove that the administration of Creatine Monohydrate® supplement could increase the estrogen levels and decrease testosterone levels in male albino rats (Rattus norvegicus) with moderate physical activity given. Methods: A true experimental with pre-test and post-test randomized control study was conducted using 14 albino male rats. The samples were divided into two groups; the control groups (P0) that received aquadest and moderate physical activity, and treatment group (P1) that received 0.4 mg Creatine Monohydrate® supplement twice a day and moderate physical activity given. Moderate physical activity (swimming) was given five times a week for 14 days. Estrogen and testosterone level were assessed before and after treatment was given. Results: Before the treatment, the estrogen and testosterone levels between P0 group and P1 group were comparable. Post-test results showed a significant different in estrogen levels between the P0 and P1 group (23.17±2.86 and 27.82±3.06 ng/ml respectively; p<0.05) as well as testosterone levels (18.15±2.95 and 21.69±2.14 ng/ml respectively; p<0.05) after 14 days of treatment. A paired analysis showed an elevating of estrogen levels but no effect on testosterone levels in P1 group that treated with Creatine Monohydrate® Conclusion: This study indicated that the administration of Creatine Monohydrate® increased the estrogen levels but have no effect on testosterone levels in male albino rats (Rattus norvegicus) with moderate physical activity.

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Using “Stages of Behavioral Change” Constructs to Measure the Short-Term Effects of a Worksite-Based Intervention to Increase Moderate Physical Activity

Psychological Reports ◽

10.2466/pr0.1998.82.2.615 ◽

1998 ◽

Vol 82 (2) ◽

pp. 615-618 ◽

Cited By ~ 17

Author(s):

Galen Cole ◽

Sharon Hammond ◽

Bruce Leonard ◽

Fred Fridinger

Keyword(s):

Physical Activity ◽

Stages Of Change ◽

Transtheoretical Model ◽

Moderate Physical Activity ◽

Short Term ◽

Incentive Program ◽

Maintenance Stage ◽

Before And After ◽

Change Concept ◽

Short Term Effects

We evaluated a three-level incentive program to promote regular, moderate physical activity among employees working in a federal agency. The objective was to assess the short-term effects of the intervention by examining the stages people go through as they attempt to make permanent changes in physical activity. Indicators of the process by which changes in physical activity take place were based on a modified version of the Transtheoretical Model of Behavior. A one-group pretest/posttest design was used to ascertain which of the stages the 1,192 participants were in both before and after the intervention. Analysis indicated that, of the 1,192 participants, 6.5% regressed one or more stages, 30.3% did not regress or progress from one stage to another, 27.7% remained in the maintenance stage, and 35.4% progressed one (21.1%) or more (14.3%) stages during the 50-day intervention. Among those who progressed, the most common change was from preparation to late preparation (20.8%) and from late preparation to action (19.4%). Findings reinforce the notion that the stages of change concept can serve as indicators of the change process which, in turn, can be used as evidence of the short-term effectiveness of interventions. Findings also indicate this type of intervention holds promise for increasing physical activity among willing participants of a worksite population.

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Impact of Moderate Individually Tailored Physical Activity in Multiple Sclerosis Patients with Fatigue on Functional, Cognitive, Emotional State, and Postural Stability

Brain Sciences ◽

10.3390/brainsci11091214 ◽

2021 ◽

Vol 11 (9) ◽

pp. 1214

Author(s):

Justyna Redlicka ◽

Ewa Zielińska-Nowak ◽

Anna Lipert ◽

Elżbieta Miller

Keyword(s):

Physical Activity ◽

Multiple Sclerosis ◽

Postural Stability ◽

Emotional State ◽

Geriatric Depression Scale ◽

Depression Scale ◽

Moderate Physical Activity ◽

Fatigue Syndrome ◽

Before And After ◽

Multiple Sclerosis Patients

Multiple sclerosis (MS) is a chronic disease, with fatigue syndrome as one of the main symptoms. The aim of this study was to demonstrate that moderate physical activity (MPA) may have a beneficial effect on postural stability, balance, and clinical parameters. The research group consisted of 137 randomized patients hospitalized at the Department of Neurological Rehabilitation, Medical University of Lodz. Finally, 76 patients were qualified who were divided into two groups—high fatigue (HF) and low fatigue (LF). Participants were assessed twice: before and after a 4-week MPA program using: the Expanded Disability Status Scale (EDSS), the Fatigue Severity Scale (FSS), the Mini-Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), the Beck Depression Inventory (BDI), and the Geriatric Depression Scale (GDS), and stabilometric platform tests were performed. Results obtained after the 4-week MPA program showed a positive effect of the MPA with differences between LF and HF groups. The MPA was more effective in MS patients with LF in cognitive functions, functional status, and postural stability but among HF patients in an emotional state, especially in MS patients below 65 years, although in total, both groups benefited from the MPA.

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Fibrinolytic responses to acute physical activity in older hypertensive men

Journal of Applied Physiology ◽

10.1152/jappl.1997.82.6.1765 ◽

1997 ◽

Vol 82 (6) ◽

pp. 1765-1770 ◽

Cited By ~ 24

Author(s):

Christopher A. Desouza ◽

Donald R. Dengel ◽

Marc A. Rogers ◽

Kim Cox ◽

Richard F. Macko

Keyword(s):

Physical Activity ◽

Plasminogen Activator ◽

Plasminogen Activator Inhibitor ◽

Tissue Type ◽

Moderate Physical Activity ◽

Plasminogen Activator Inhibitor 1 ◽

Acute Bout ◽

Type Plasminogen Activator ◽

Before And After ◽

Pai 1

DeSouza, Christopher A., Donald R. Dengel, Marc A. Rogers, Kim Cox, and Richard F. Macko. Fibrinolytic responses to acute physical activity in older hypertensive men. J. Appl. Physiol. 82(6): 1765–1770, 1997.—We tested the hypothesis that the fibrinolytic response to acute physical activity is impaired in sedentary older hypertensive men, which may contribute to the risk of exertion-triggered acute myocardial infarction in this population. Tissue-type plasminogen activator (t-PA) antigen and activity and plasminogen activator inhibitor-1 (PAI-1) antigen and activity were measured in 12 hypertensive (69 ± 1 yr) and 11 normotensive (64 ± 1 yr) men before and after an acute bout of submaximal exercise. Contrary to our hypothesis, there were no differences between the two groups in the fibrinolytic response to exercise. t-PA antigen and activity were significantly elevated in both the hypertensive (38 and 172%, respectively) and normotensive (45 and 130%, respectively) groups immediately after exercise but they returned to resting levels within 30 min. There was no change in PAI-1 antigen levels immediately after exercise in either group; however, PAI-1 antigen was significantly lower at 30 and 60 min postexercise in both the hypertensive (31 and 16%, respectively) and normotensive (35 and 20%, respectively) groups. PAI-1 activity was significantly lower immediately after exercise in both the hypertensive (25%) and normotensive (22%) groups and remained lower than preexercise levels at 30 min (23 and 26%, respectively) and 60 min (16 and 12%, respectively) postexercise in both groups. The results of this study demonstrate that the fibrinolytic response to an acute bout of moderate physical activity is not impaired in sedentary older hypertensive men.

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THE PERSPECTIVE OF CLINICAL CLERKSHIP STUDENTS ON HEALTH PROTOCOLS DURING THE COVID-19 PANDEMIC ON DAILY EXERCISE ACTIVITIES

GLADI JURNAL ILMU KEOLAHRAGAAN ◽

10.21009/gjik.122.11 ◽

2021 ◽

Vol 12 (02) ◽

pp. 194-206

Author(s):

Santi Anugrahsari ◽

Nining Parlina ◽

Muhammad Ikhwan Zein ◽

Ayatullah Muhammad Resza ◽

Suryadi ◽

...

Keyword(s):

Physical Activity ◽

Short Form ◽

Sport Activity ◽

Moderate Physical Activity ◽

Clinical Clerkship ◽

Daily Exercise ◽

Post Test ◽

Educational Videos ◽

Sports Activities ◽

Activity Questionnaire

Physical exercise is essential to maintain human health. However, everybody has to apply the health protocols to prevent COVID-19 transmission during the pandemic. There is no exception; it is also applied for Clinical Clerkship Students who undergo the learning process at the Teaching Hospital. Unfortunately, no research provides a perspective on health protocol during the COVID-19 pandemic on daily exercise activities. This study aims to research the sports activities of Clinical Clerkship Students, measure knowledge about distance when exercising according to the protocol from the Ministry of Health, and describe their opinion regarding health protocols. This research conducted a mixed-method experiment that studies twenty-eight Clinical Clerkship Students. The type of sport and its frequency were evaluated using the International Physical Activity Questionnaire (IPAQ) short form. The enhancement of participants’ knowledge after watching the video and sport activity were studied descriptive quantitatively. Meanwhile, their opinion on the health protocol was analyzed qualitatively. The participants' Physical Activity Categories were 25% low, 50% moderate, and 25% high. The results showed that low and high IPAQ Catagories have a higher video post-test score, but there was no correlation. More than 75% of the students understand the contents of health protocols during exercise. We conclude that half of Clinical Clerkship Students have a moderate physical activity category and know about distance when exercising through educational videos and believe that maintaining health during a pandemic by exercising is necessary as long as they adhere to health protocols.

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The role of postural control in physical activity

Physiotherapy and Health Activity ◽

10.1515/pha-2016-0005 ◽

2016 ◽

Vol 24 (1) ◽

pp. 31-40

Author(s):

Małgorzata Matyja ◽

Joanna Dzierżęga

Keyword(s):

Physical Activity ◽

Postural Control ◽

Body Position ◽

Moderate Physical Activity ◽

Support Surface ◽

Reflex Mechanism ◽

Postural Reflex ◽

Before And After ◽

Two Parameters ◽

Postural Tone

Abstract Background: Postural control concerns control of body position in space in two aspects: 1. stability that is understood as ability to maintain projection of center of gravity on support surface 2. orientation understood as proper relation of individual body segments towards each other and towards surrounding In pediatric physiotherapy different term is used that constitute synonym of postural control - it is postural reflex mechanism of which the most important factor is postural tone Aim of study: To determine relation between postural control and moderate physical activity in children? Material/Methods: Method used in the study encompasses physiotherapeutic assessment of postural control before and after two weeks period of moderate physical activity. It included multi-sport activities (with prevalence of activities with use of water equipment), that stimulate postural control. 23 children (11 girls and 12 boys) aged 7-16 were examined. Their postural control was assessed with use of two parameters: size of postural tone (Postural Tone Coefficient) and body stabilization (Body Stabilization Test). Obtained results were processed statistically Results: After two weeks of moderate physical activity, parameters that concern postural control were improved. In the statistical analyze improvement appears to be statistically significant on the level of p < 0,05. Conclusions: Moderate physical activity influences postural control improvement.

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Effects of Physical Activity and Counselling Interventions on Health Outcomes among Working Women in Shanghai: A randomized controlled trial

10.21203/rs.2.13443/v3 ◽

2020 ◽

Author(s):

Hongying Wang ◽

Yi Xiao ◽

Xiaoling Ren ◽

Pei Zhang ◽

MiaoMiao Lu ◽

...

Keyword(s):

Physical Activity ◽

Health Outcomes ◽

Work Stress ◽

Intervention Group ◽

Working Women ◽

Control Group ◽

Moderate Physical Activity ◽

Significant Difference ◽

Before And After ◽

Counselling Intervention

Abstract Background：Working women in Shanghai are a special group with a high risk of suffering work stress and burnout. They were disturbed by the work-family conflicts, which resulted in lower health-related quality of life (HRQoL), higher job stress and burnout. This study evaluated the potential physical activity and counselling intervention effects on health outcomes of working women in Shanghai participating in a group- or an individual-based physical activity and counselling intervention compared to a control group.Methods：Participants were randomly recruited from eight communities of Shanghai using the stratified cluster sampling method. A sample of 121 female workers was used in this study. They were randomly divided into three groups: a control group and two intervention groups (individual-based and group-based intervention). The two intervention groups accepted 12-week moderate physical activity and counselling intervention. Subjective perceptions of work stress, burnout, and HRQoL were measured before and after the intervention. Results：In the control group, no significant difference was found between participants for stress (p = 0.752) and burnout (p = 0.622) before and after the experiment. However, the HRQoL value decreased after the experiment, with the mean value falling from 91.59 to 87.10. After the experiment, the values of stress and burnout decreased, and the value of HRQoL increased in the two intervention groups. At the intervention’s completion, there were significant differences compared the two intervention groups to the control group separately regarding changes in burnout and HRQoL (all p < 0.01). For stress, the group-based intervention group exhibited a significant difference compared to the control group (p < 0.01), while the individual-based intervention group did not exhibit a significant difference compared to the control group (p = 0.128).Conclusion: Physical activity and counselling intervention delivered either in a group or individual format could reduce burnout and improve HRQoL of working women in Shanghai, and the group interventions were more effective than those targeted at individuals.

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Working from Home After the COVID-19 Pandemic: Do Company Employees Sit More and Move Less?

Sustainability ◽

10.3390/su13020939 ◽

2021 ◽

Vol 13 (2) ◽

pp. 939

Author(s):

Mohammad Javad Koohsari ◽

Tomoki Nakaya ◽

Ai Shibata ◽

Kaori Ishii ◽

Koichiro Oka

Keyword(s):

Physical Activity ◽

Physical Activities ◽

Sitting Time ◽

Moderate Physical Activity ◽

Work Related ◽

Domain Specific ◽

Sedentary Behaviours ◽

Working From Home ◽

Work Style ◽

Before And After

Background–Several non-pharmaceutical policies, which include stay-at-home orders, mobility restrictions, and quarantine, have been implemented to reduce the spread of novel coronavirus disease 2019 (COVID-19). The present study examines work style changes among company workers after COVID-19 and analyses their effects on workers’ domain-specific sedentary and active behaviours. Methods - We analysed data from a nationwide prospective online survey in Japan. The data were obtained in February 2019 (n = 3200) and in July 2020 (n = 1709) from the registered individuals of a Japanese internet research service company. The participants reported work style patterns before and after the outbreak of COVID-19 in the follow-up survey. Domain-specific sedentary behaviours and physical activities were assessed by questionnaires. Paired t-tests were used to compare work styles before and after the outbreak of COVID-19. Multivariable linear regression models were used to assess the associations between changes in work style and changes in sedentary behaviours and physical activities. Results. Workers had more working from home days and fewer office-based working days after the outbreak of COVID-19 (p < 0.001 and p < 0.001, respectively). The increase in the number of working from home days per week was significantly associated with increases in work-related sitting time and total sitting time (b = 0.16, 95% CI 0.08, 0.24, p < 0.001 and b = 0.23, 95% CI 0.11, 0.36, p < 0.001, respectively). However, it was also associated with a decrease in car sitting time (b = −0.04, 95% CI −0.06, -0.01, p < 0.001). In addition, the increase in the number of working from home days was associated with a decrease in work-related moderate physical activity (b =−0.06, 95% CI −0.10, −0.02, p < 0.001). Conclusions. Our study provided preliminary evidence of an increase in working from home days in response to COVID-19 in Japan and of how this increase in the number of working from home days has affected workers’ sedentary behaviours and physical activities. These findings shed light on the effects of COVID-19 on work styles and workers’ sedentary behaviours and physical activity.

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The Impacts of Building a Greenway on Proximate Residents’ Physical Activity

Journal of Physical Activity and Health ◽

10.1123/jpah.8.8.1092 ◽

2011 ◽

Vol 8 (8) ◽

pp. 1092-1097 ◽

Cited By ~ 27

Author(s):

Stephanie T. West ◽

Kindal A. Shores

Keyword(s):

Physical Activity ◽

Survey Data ◽

Additional Research ◽

Moderate Physical Activity ◽

Moderate Activity ◽

Activity Levels ◽

Before And After ◽

Positive Effect

Background:A significant association has been identified between physical activity and proximity to greenways. However, residents more likely to be active may have selected to live near existing greenways. The purpose of this study was to determine whether development of a new greenway has the potential to increase activity levels of existing, proximate residents.Methods:In 2008, survey data were collected before and after 5 miles of greenway were added to an existing greenway.Results:When comparing residents living nearest (≤ .50 miles) the new greenway section with those living further (.51−1.0 miles), days spent walking and participating in moderate physical activity increased. Despite mean increases, no significant interactions were detected.Conclusions:Although evidence is inconclusive, apparent increases in walking and moderate activity suggest development of a greenway proximate to residents’ homes is likely to have a positive effect on participation levels. Additional research is needed to address article limitations.

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The Effect of Mangosteen Rind Extract (Garcinia mangostana L.) Toward Stress Oxidative Parameter, Leukocytes, Leukocytes Type Counts on Male Rats (Rattus norvegicus) with Excessive Physical Activity

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2020.5448 ◽

2020 ◽

Vol 8 (A) ◽

pp. 904-909

Author(s):

Rika Nailuvar Sinaga ◽

Zulaini Zulaini

Keyword(s):

Oxidative Stress ◽

Physical Activity ◽

Rattus Norvegicus ◽

Leukocyte Count ◽

The Body ◽

Male Rats ◽

Control Group ◽

Garcinia Mangostana ◽

Average Percentage ◽

White Rats

BACKGROUND: Excessive and heavy physical activity could lead to the oxidative stress in the body. This condition can affect several blood parameters such as malondialdehyde (MDA), glutathione peroxidase (GPx), leukocytes, and its type counts. One way to overcome the effects of oxidative stress due to strenuous physical activity is by giving natural antioxidants. Mangosteen rind (Garcinia mangostana L.) contains considerable antioxidants, namely, xanthones and procyanidin. AIM: This research aimed to investigate the effect of mangosteen rind extract (MRE) on oxidative stress parameters, leukocyte count, and leukocyte count in male rats (Rattus norvegicus) that received excessive physical activity. METHODS: This study was purely experimental research with a post-test only control group design, using 29 white rats (R. norvegicus) as experimental animals, which were divided into four groups. The first group (P1) received distilled water and the other group received MRE at a dose of 50 mg/KgBW (Body Weight) (P2), 100 mg/KgBW (P3), and 200 mg/KgBW (P4) for 3 weeks, respectively. Swimming as a physical activity was carried out 3 times a week in all groups. Examination of leukocyte count and species was carried out on the last day of treatment after the rats swam to fatigue. RESULTS: MDA levels did not decrease significantly while GPx activity increased significantly. Moreover, the average leukocytes and lymphocytes showed a decrease but not significant. A significant decrease in the percentage of neutrophils and basophils was obtained by P4 group compared to others. In addition, a significant decrease in the average percentage of eosinophils for P3 and P4 groups was obtained. Furthermore, P3 and P4 group exhibit significant increase of the average percentage of monocytes. CONCLUSION: MRE as an antioxidant affects the levels of neutrophils, basophils, eosinophils, and monocytes but not in MDA, GPx, leukocytes, and lymphocytes.

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Aktivitas fisik moderat meningkatkan rasio jumlah otot polos dan kolagen pada penis tikus tua (Rattus norvegicus)

Bali Anatomy Journal ◽

10.36675/baj.v1i1.8 ◽

2018 ◽

Vol 1 (1) ◽

pp. 1-4

Author(s):

Raoulian Irfon ◽

I Nyoman Mangku Karmaya ◽

Yuliana .

Keyword(s):

Physical Activity ◽

Smooth Muscle ◽

Rattus Norvegicus ◽

Corpus Cavernosum ◽

Test Group ◽

Control Group ◽

Moderate Physical Activity ◽

Control Group Design ◽

Aged Mice ◽

Old Mice

Aging process is related with the increase of free radicals numbers that will lead to destruction of body structures including penis by the degradation of smooth muscle and the increasing of collagen numbers. Moderate physical activity is prospected to have an antioxidant effect that will maintain the penis structure. Aim: The aim of this study it to determine that the physical activity can increase the ratio of smooth muscle and collagen in penis of aged mice. Methods: This study was experimental posttest only control group design. Fourteen 18-month old mice were divided into two group, control and test group. Swimming 30 minutes/day for 8 weeks was conducted on the test group. After 8 weeks experiment, Corpus cavernosum were then collected from the mice and stained with Sirius red staining. The penis preparation were examined under the microscope and analyzed with photoshop cs 6 to get the pixel amounts of smooth muscle and collagen. Results: The result shows the mean of smooth muscle and collagen ratio for control group is 0.156 ± 0.021 and 0.312 ± 0.005 for the test group. This result shows that there is a difference between the smooth muscle and collagen ratio between the control and test group (p < 0.05). The smooth muscle and collagen ratio is higher in the test group than the control group. Conclusion: The physical activity increases the smooth muscle and collagen ratio in penis of aged mice (Rattus norvegicus).

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