scholarly journals Differential Evolution in Wireless Communications: A Review

2019 ◽  
Vol 15 (11) ◽  
pp. 29
Author(s):  
Hilary I Okagbue ◽  
Muminu O Adamu ◽  
Timothy A Anake
Keyword(s):  
Wireless Communications ◽  
Differential Evolution ◽  
Computational Method ◽  
Biological Processes ◽  
Search Region ◽  
Coverage Area ◽  
Related Field ◽  
Research Areas ◽  
Scientific Fields

<p class="0abstract">Differential Evolution (DE) is an evolutionary computational method inspired by the biological processes of evolution and mutation. DE has been applied in numerous scientific fields. The paper presents a literature review of DE and its application in wireless communication. The detailed history, characteristics, strengths, variants and weaknesses of DE were presented. Seven broad areas were identified as different domains of application of DE in wireless communications. It was observed that coverage area maximisation and energy consumption minimisation are the two major areas where DE is applied. Others areas are quality of service, updating mechanism where candidate positions learn from a large diversified search region, security and related field applications. Problems in wireless communications are often modelled as multiobjective optimisation which can easily be tackled by the use of DE or hybrid of DE with other algorithms. Different research areas can be explored and DE will continue to be utilized in this context.</p>

scholarly journals Annotating proteins with generalized functional linkages

2008 ◽  
Vol 105 (46) ◽  
pp. 17700-17705 ◽  
Author(s):  
Richard Llewellyn ◽  
David S. Eisenberg
Keyword(s):  
Protein Function ◽  
Biological Process ◽  
Computational Method ◽  
Majority Voting ◽  
Target Protein ◽  
Biological Processes ◽  
Gene Products ◽  
Protein Protein Interaction ◽  
Protein Protein Interaction Networks

As genome sequencing outstrips the rate of high-quality, low-throughput biochemical and genetic experimentation, accurate annotation of protein function becomes a bottleneck in the progress of the biomolecular sciences. Most gene products are now annotated by homology, in which an experimentally determined function is applied to a similar sequence. This procedure becomes error-prone between more divergent sequences and can contaminate biomolecular databases. Here, we propose a computational method of assignment of function, termed Generalized Functional Linkages (GFL), that combines nonhomology-based methods with other types of data. Functional linkages describe pairwise relationships between proteins that work together to perform a biological task. GFL provides a Bayesian framework that improves annotation by arbitrating a competition among biological process annotations to best describe the target protein. GFL addresses the unequal strengths of functional linkages among proteins, the quality of existing annotations, and the similarity among them while incorporating available knowledge about the cellular location or individual molecular function of the target protein. We demonstrate GFL with functional linkages defined by an algorithm known as zorch that quantifies connectivity in protein–protein interaction networks. Even when using proteins linked only by indirect or high-throughput interactions, GFL predicts the biological processes of many proteins in Saccharomyces cerevisiae, improving the accuracy of annotation by 20% over majority voting.

scholarly journals Allocation For Wi-Fi Devices At Campus of Udayana University in Bukit Jimbaran Using Atoll Applications

2018 ◽  
Vol 2 (1) ◽  
pp. 11
Author(s):  
Pande Ketut Sudiarta ◽  
Nyoman Pramaita
Keyword(s):  
Wireless Communications ◽  
University Campus ◽  
Coverage Area ◽  
Engineering Faculty ◽  
Internet Networks

Access to intranet and internet networks in the campus area requires a number of Wi-Fi devices to cover the coverage area of Udayana University. The Wi-Fi service is expected to be used for VoIP applications in the context of wireless communications. The IEEE 802.11g standard specifies an outdoor service range of 140 m and an indoor service range of 38 m. From research conducted in the engineering faculty area, the quality of VoIP service uses Wi-Fi with range of 25 m. In this research, the design of Udayana University campus Wi-Fi needs using Atoll application with IEEE802.11g standard at 140 m, 38m and 25m ranges. The results obtained to cover Udayana University campus area require Wi-Fis: 7 units for range 140 m, 98 units for range of 38 m and 225 units for range of 25 m

scholarly journals 104 - Awareness of Dementia and Coping to Preserve Quality of Life: A Five-Year Longitudinal Narrative Study

2020 ◽  
Vol 32 (S1) ◽  
pp. 8-8
Author(s):  
K. Thorsen ◽  
M. C. N. Dourado ◽  
A. Johannessen
Keyword(s):  
Quality Of Life ◽  
Coping Styles ◽  
Adaptive Function ◽  
Narrative Study ◽  
People With Dementia ◽  
The Moment ◽  
And Coping ◽  
Scientific Fields ◽  
Multidimensional Concept

AbstractBackground:Awareness of dementia is examined in different scientific fields as significant for assessment of diagnosis, and for treatment and adaptation to the disease. There are very few longitudinal studies of individual experiences of awareness among people with dementia, related to quality of life.Aim:To examine how younger people (< 65 years) with dementia (YOD) express awareness of the dementia and how, over time, they seem to handle awareness as a strategy to preserve quality of life.Method:A longitudinal qualitative study with individuals with YOD was performed with interviews every six months over five years for a maximum of ten interviews. The interviews were analysed by modified grounded theory.Findings:Awareness is a complex, multidimensional concept. Awareness of dementia is predisposed by personality, life history and established coping styles. The main coping styles – live in the moment, ignore the dementia, and make the best of it – seem to be rather consistent throughout the progression of the disease. Transitions in life situation, such as moving to a nursing home, may change the individual’s awareness of dementia.Conclusion:Unawareness of dementia may have an important adaptive function to preserve quality of life. To increase awareness must be approached with reflexivity and the utmost sensitivity.

scholarly journals Integrative, multi-omics, analysis of blood samples improves model predictions: applications to cancer

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Erica Ponzi ◽  
Magne Thoresen ◽  
Therese Haugdahl Nøst ◽  
Kajsa Møllersen
Keyword(s):  
Lung Cancer ◽  
Biological Process ◽  
Case Control ◽  
Integrative Analysis ◽  
Data Sources ◽  
Omics Data ◽  
Biological Processes ◽  
Blood Samples ◽  
Model Predictions

Abstract Background Cancer genomic studies often include data collected from several omics platforms. Each omics data source contributes to the understanding of the underlying biological process via source specific (“individual”) patterns of variability. At the same time, statistical associations and potential interactions among the different data sources can reveal signals from common biological processes that might not be identified by single source analyses. These common patterns of variability are referred to as “shared” or “joint”. In this work, we show how the use of joint and individual components can lead to better predictive models, and to a deeper understanding of the biological process at hand. We identify joint and individual contributions of DNA methylation, miRNA and mRNA expression collected from blood samples in a lung cancer case–control study nested within the Norwegian Women and Cancer (NOWAC) cohort study, and we use such components to build prediction models for case–control and metastatic status. To assess the quality of predictions, we compare models based on simultaneous, integrative analysis of multi-source omics data to a standard non-integrative analysis of each single omics dataset, and to penalized regression models. Additionally, we apply the proposed approach to a breast cancer dataset from The Cancer Genome Atlas. Results Our results show how an integrative analysis that preserves both components of variation is more appropriate than standard multi-omics analyses that are not based on such a distinction. Both joint and individual components are shown to contribute to a better quality of model predictions, and facilitate the interpretation of the underlying biological processes in lung cancer development. Conclusions In the presence of multiple omics data sources, we recommend the use of data integration techniques that preserve the joint and individual components across the omics sources. We show how the inclusion of such components increases the quality of model predictions of clinical outcomes.

scholarly journals The Etiology and Pathophysiology Genesis of Benign Prostatic Hyperplasia and Prostate Cancer: A New Perspective

Medicines ◽  
2021 ◽  
Vol 8 (6) ◽  
pp. 30
Author(s):  
Teow J. Phua
Keyword(s):  
Prostate Cancer ◽  
Benign Prostatic Hyperplasia ◽  
Cell Biology ◽  
Cancer Biology ◽  
Cost Savings ◽  
Prostatic Hyperplasia ◽  
Biological Processes ◽  
New Perspective ◽  
Prostatic Diseases

Background: The etiology of benign prostatic hyperplasia and prostate cancer are unknown, with ageing being the greatness risk factor. Methods: This new perspective evaluates the available interdisciplinary evidence regarding prostate ageing in terms of the cell biology of regulation and homeostasis, which could explain the timeline of evolutionary cancer biology as degenerative, inflammatory and neoplasm progressions in these multifactorial and heterogeneous prostatic diseases. Results: This prostate ageing degeneration hypothesis encompasses the testosterone-vascular-inflamm-ageing triad, along with the cell biology regulation of amyloidosis and autophagy within an evolutionary tumorigenesis microenvironment. Conclusions: An understanding of these biological processes of prostate ageing can provide potential strategies for early prevention and could contribute to maintaining quality of life for the ageing individual along with substantial medical cost savings.

Neurotechnology as a factor of the educational process transformation

2021 ◽  
pp. 98-13
Author(s):  
Л.Д. Александрова ◽  
Р.А. Богачева ◽  
Т.А. Чекалина ◽  
М.В. Максимова ◽  
В.И. Тимонина
Keyword(s):  
Effective Means ◽  
Individual Characteristics ◽  
Educational Process ◽  
Special Equipment ◽  
Research Areas ◽  
Long Time ◽  
Mental Abilities ◽  
The Individual ◽  
And Control

Изучение возможностей мозга для повышения качества обучения находится в центре внимания педагогической науки уже много лет. Развитие цифровизации позволило использовать в исследованиях специальное оборудование, с помощью которого можно оценивать и контролировать работу мозга, развивать умственные способности, познавательные функции и т. п. Нейротехнологии стали эффективным средством, позволяющим трансформировать образовательный процесс за счет подбора специального учебного контента с учетом индивидуальных особенностей обучающихся. Вместе с тем возникает необходимость в конкретизации терминологии и определении актуальных направлений исследований в данной области. For a long time, the study of the brain capabilities for the improvement of the quality of education has been an urgent direction in pedagogical science. Due to the development of digitalization, new areas of research have emerged related to the use of special equipment that makes it possible to assess and control brainwork, develop mental abilities, cognitive functions, etc. One of them is neurotechnology, which is an effective means of transforming the educational process: it offers educational content based on the individual characteristics of students. Thus, a need to concretize the terminology and determine the current research areas arises. The article aims to attempt to fill this gap with the help of a representative analysis of publications on neurotechnologies, as well as the essence of neuroeducation.

scholarly journals FPGA–implementation of PID-controller by differential evolution optimization

2018 ◽  
Vol 8 (1) ◽  
pp. 395-402
Author(s):  
Mika Hanhila ◽  
Timo Mantere ◽  
Jarmo T. Alander
Keyword(s):  
Differential Evolution ◽  
Pid Controller ◽  
Differential Evolution Algorithm ◽  
Fpga Implementation ◽  
Solution Convergence ◽  
Fitness Value ◽  
Mutation Operation ◽  
Self Adaptation ◽  
Evolution Algorithm

Abstract We will describe an FPGA implementation of PID-controller that uses differential evolution to optimize the coefficients of the PID controller, which has been implemented in VHDL. The original differential evolution algorithm was improved by ranking based mutation operation and self-adaptation of mutation and crossover parameters. Ranking-based mutation operation improves the quality of solution, convergence rate and success of optimization. Due to the self-adaptive control parameters, the user does not have to estimate the mutation and crossover rates. Optimization have been performed by calculating for each generation fitness value by means of trial parameters. The final optimal parameters are selected based on the minimum fitness.

scholarly journals Disaggregases, molecular chaperones that resolubilize protein aggregates

2015 ◽  
Vol 87 (2 suppl) ◽  
pp. 1273-1292 ◽  
Author(s):  
David Z. Mokry ◽  
Josielle Abrahão ◽  
Carlos H.I. Ramos
Keyword(s):  
Heat Shock ◽  
Molecular Chaperones ◽  
Protein Function ◽  
Protein Aggregates ◽  
Cell Physiology ◽  
Biological Processes ◽  
Loss Of Function ◽  
Prion Propagation ◽  
Shock Proteins

The process of folding is a seminal event in the life of a protein, as it is essential for proper protein function and therefore cell physiology. Inappropriate folding, or misfolding, can not only lead to loss of function, but also to the formation of protein aggregates, an insoluble association of polypeptides that harm cell physiology, either by themselves or in the process of formation. Several biological processes have evolved to prevent and eliminate the existence of non-functional and amyloidogenic aggregates, as they are associated with several human pathologies. Molecular chaperones and heat shock proteins are specialized in controlling the quality of the proteins in the cell, specifically by aiding proper folding, and dissolution and clearance of already formed protein aggregates. The latter is a function of disaggregases, mainly represented by the ClpB/Hsp104 subfamily of molecular chaperones, that are ubiquitous in all organisms but, surprisingly, have no orthologs in the cytosol of metazoan cells. This review aims to describe the characteristics of disaggregases and to discuss the function of yeast Hsp104, a disaggregase that is also involved in prion propagation and inheritance.

scholarly journals Roles of Extracellular Vesicles in High-Grade Gliomas: Tiny Particles with Outsized Influence

2019 ◽  
Vol 20 (1) ◽  
pp. 331-357 ◽  
Author(s):  
Michael W. Graner
Keyword(s):  
Extracellular Vesicles ◽  
Standard Of Care ◽  
High Grade ◽  
Biological Processes ◽  
Current Standard ◽  
Endocrine Factors ◽  
High Grade Gliomas ◽  
Endosomal System ◽  
Intercellular Communications

High-grade gliomas, particularly glioblastomas (grade IV), are devastating diseases with dismal prognoses; afflicted patients seldom live longer than 15 months, and their quality of life suffers immensely. Our current standard-of-care therapy has remained essentially unchanged for almost 15 years, with little new therapeutic progress. We desperately need a better biologic understanding of these complicated tumors in a complicated organ. One area of rejuvenated study relates to extracellular vesicles (EVs)—membrane-enclosed nano- or microsized particles that originate from the endosomal system or are shed from the plasma membrane. EVs contribute to tumor heterogeneity (including the maintenance of glioma stem cells or their differentiation), the impacts of hypoxia (angiogenesis and coagulopathies), interactions amid the tumor microenvironment (concerning the survival of astrocytes, neurons, endothelial cells, blood vessels, the blood–brain barrier, and the ensuing inflammation), and influences on the immune system (both stimulatory and suppressive). This article reviews glioma EVs and the ways that EVs manifest themselves as autocrine, paracrine, and endocrine factors in proximal and distal intra- and intercellular communications. The reader should note that there is much controversy, and indeed confusion, in the field over the exact roles for EVs in many biological processes, and we will engage some of these difficulties herein.

scholarly journals Scientometric analysis activity in the publication «life sciences» in the world and in Ukraine

2019 ◽  
pp. 23-33
Author(s):  
V.M. Yevtushenko
Keyword(s):  
Core Collection ◽  
Web Of Science ◽  
Journal Citation Report ◽  
Life Sciences ◽  
Scientometric Analysis ◽  
Research Areas ◽  
The World ◽  
Scientific Papers ◽  
Scientific Fields ◽  
The Web

The article is devoted to the study of the state and trends of the publishing activity of Ukrainian scientists and leading countries in the field of life sciences («Life sciences»). The Web of Science Core Collection (WoS CC), Journal Citation Report (JSR) and InCites, as well as classifications of scientific fields designed to structure the publication flow of scientific papers and journals in these information resources, are used for the research base – Web of Science Categories and Research Areas. The article presents the results of the author’s research on the publication indices of scientists of Ukraine and the leading countries of the world for the period 2008-2018 in the field of “Life Sciences” according to the international science-computer database of Web of Science. Conclusions about the growth of indicators of publication activity of scientific works in the field of “Life Sciences” are made. The tendency of a significant increase in their number in Ukraine has been revealed, but domestic studies do not represent all the areas of «Life Sciences» most popular in foreign scientists

Sign in / Sign up

Export Citation Format

Share Document