scholarly journals The Concentrations of Cholesterol and Reproduction Hormones in Serum of Rabbits Doe That Consumed Moringa oleifera Leaf Extracts

Author(s):  
Setiasih Setiasih ◽  

This study was conducted to examine the effect of various kinds of Moringa leaf extracts on cholesterol, estradiol, FSH, LH levels and litter size in rabbit does. The extracts used were hexane fraction extract (HeEF), ethanol fraction extract (EtEF) and ethanol rough extract (EtCE) from moringa leaf flour. Seven treatments were administered including extracts in pellets at a dose of 0, 0.13% HeEF, 0.26% HeEF, 0.37 EtEF, 0.74% EtEF, 0.54% EtCE and 1.08% EtCE. Each treatment was reduplicated on 4 rabbits. Cholesterol levels, estradiol, LH and FSH blood serum, mating readiness and litter size were measured, which results showed that the treatment significantly (P <5%) lowered the cholesterol level and increased the estradiol level in blood serum. On the other hand, the treatment had no significant effect on FSH, LH and litter size levels except at LH levels 2 hours after mating.

1988 ◽  
Vol 41 (4) ◽  
pp. 403 ◽  
Author(s):  
AS Al-Janabi ◽  
SR AI-Kattib ◽  
Z D Taha

Ascorbic acid (vitamin C) was given to 144-days-old layer chickens mixed with their ration at three concentrations: 30, 60 and 90 p.p.m. for 6 months. Cholesterol levels in blood serum (CS) and egg yolk (CE) were measured every 6 weeks (four periods); there was a marked decrease in CS in most treated birds, especially those receiving the highest concentration of vitamin C. There was also a slight decrease in CE in most treated birds. Thyroidal weight showed a significant increase in most treated groups, especially those receiving the highest concentration of vitamin C.


2016 ◽  
Vol 43 (3) ◽  
pp. 73
Author(s):  
Fransiscus H Wulur ◽  
Recky Dj B Pieter

Background Hypercholesterolemia in children is an important riskfactor that causes coronary heart disease in the future. Nutritionalstatus, especially overweight/obesity, is associated with hyperc-holesterolemia.Objective To determine the prevalence of hypercholesterolemiaand its association with nutritional status.Methods This was a cross sectional study conducted during April-June 2001. Subjects consisted of children aged 10-12 year-oldregistered at primary schools in Manado, Tondano, and TandenganMinahasa. Data were analyzed using t test, z score, and chi-square.Results Of the 229 samples, 153 (66.8%) were boys and 76 (33.2%) were girls. The mean of total cholesterol level in boys was 179.46mg/dL (SD 33.44) and in girls was 180.95 mg/dL (SD 33.77) whichwas not significantly different (p>0.05). There were no differencesin either the number of children having “borderline” cholesterol level(170–199 mg/dL) or hypercholesterolemia (3200 mg/dL) betweenboth sexes. Of the 229 children, 65 (28.4%) had hypercholester-olemia. Of the 65 children, 37 (36%) came from the primary schoolin Manado, which was significant compared to the other schoollocations (p<0.05). Twenty-five (39%) children with hypercholes-terolemia had overweight nutritional status, which was significantcompared to the other nutritional status (p<0.05).Conclusion The prevalence of hypercholesterolemia was 28.4 %.There was an association between hypercholesterolemia and nutri-tional status, with a tendency of hypercholesterolemia to occur atoverweight nutritional status, especially in the urban area


2019 ◽  
Vol 1 (1) ◽  
pp. 97-110
Author(s):  
Sri Wahyu ◽  
Andi Sitti Fahirah Arsal ◽  
Indah Chintya Maharani

Introduction: The prevalence of hypercholesterolemia in Indonesia is estimated to increased continously. One of the traditional medicines used to reduce blood cholesterol levels is Moringa oleifera Lam, After using the extract of Moringa leaves, the cholesterol levels slowly reduced, it because by the active substance component on Moringa leaves such as flavanoid, tannin saponin and β-sitosterol. Objective : To determine the effect of Moringa leaf extract on reduce total cholesterol levels. Methods : The research is an analytical research, using pre-experimental design with one group pre-test method post-test approach. By comparing treatment groups and control groups where the treatment group was treated on the form of Moringa leaf extract. Results: The Paired T test showed that in the treatment group using Moringa leaf extract obtained before intervention the average cholesterol level was 307.40 mg/dl and after the interval was 209.00 mg/dl. Statistical test results obtained p value (0.00041) <0.05 which means that there is a difference of the mean cholesterol level between before and after treatment. Besides, the group using simvastatin was obtained before the intervention of the average cholesterol level was 271.20 mg/dl and after the interval was 127.40 mg/dl. Statistical test results obtained p value (0.009) <0.05 which means that there is a difference of the mean cholesterol level between before and after treatment. Conclusion: There wasn’t any significant differences between the Moringa leaves and simvastatin use to reduce the total blood cholesterol levels.


2021 ◽  
Vol 2 (3) ◽  
pp. 27-38
Author(s):  
Ibrahim Sani ◽  
Angela Nnenna Ukwuani-Kwaja ◽  
Timothy Eromosele Ehebha

This research was designed to evaluate the antipyretic activity of K. senegalensis leaf extract with the view of isolating and identifying the active components. The K. senegalensis leaf was extracted using 90% methanol and further fractionated with hexane, ethylacetate, n-butanol and distilled water.The qualitative phytochemical screening was carried out using standard methods.The crude extract and the fractions were screened for antipyretic activity using 15%w/v brewer’s yeast induced pyrexia on Albino rats. The components of the most active fraction were further separated using column and thin layer chromatographic techniques on silica gel. LD50 of the most active fraction was determined using probit analysis. The results of the phytochemical screening revealed the presence of tannins, phenols, steroids and cardiac glycosides in both the crude extract and its fractions. The crude extract at 400 mg/kg b.w. showed the highest antipyretic activity compared to the other doses tested. Hexane fraction showed the highest antipyretic activity among the other fractionated extracts. The LD50 of the hexane fraction was found to be 831.76 mg/kg b.w. The column chromatographic separation of the hexane extract yielded 60 fractions (F1 to F60). After TLC separation, fractions with similar profile were pooled together yielding eleven (11) pooled fractions (PF1 to PF11). Antipyretic activities of the pooled fractions showed that PF8 exhibited the highest activity. These findings suggested that, K. senegalensis leaf has significant antipyretic activity which can be considered for the development of antipyretic agent from natural resources.


2021 ◽  
Vol 4 (2) ◽  
pp. 221
Author(s):  
Ratna Dwi Lestari ◽  
Widya Paramita Lokapirnasari ◽  
Muhammad Anam Al Arif ◽  
Sri Hidanah ◽  
Soeharsono Soeharsono ◽  
...  

The purpose of this research was to determine the effect of supplementary feeding with fermented Moringa leaf flour on cholesterol levels of Mojosari duck eggs and to calculate the cost of production. This study used 60 mojosari ducks, layer phase aged 27 weeks. Moringa flour was fermented using probiotics and given in four treatments, namely P0 (100% commercial feed), P1 (0.5% moringa leaf flour fermentation + 100% commercial feed), P2 (1% moringa leaf flour fermentation + 100% commercial feed), P3 (1.5% fermented Moringa leaf meal + 100% commercial feed). The variable observed in this study was cholesterol levels in Mojosari duck eggs. The results showed thatgiving Moringa leaf flour fermentation can give significantly different values (p <0.05) in each treatment both P0, P1, P2 and P3.In the fermentation of moringa leaf flour as much as 1.5% (P3) had the lowest cholesterol levels (113.13 ± 12.55) Meanwhile, 1% (P2) of moringa leaf flour fermentation has the highest cholesterol level (170.42 ± 13.19).


Author(s):  
Dedi Rahmat Dudi Sayu Putu Yuni Paryati

Abstrak Penelitian dilakukan untuk mengetahui pengaruh keragaman gen DGAT1 pada domba Padjadjaran terhadap kandungan kolesterol dan trigiserida darah. Ternak domba yang digunakan dalam penelitian ini merupakan domba Padjadjaran umur 1,5 tahun, yang telah diidentifikasi memiliki genotipe tertentu berdasarkan gen DGAT1. Total sampel domba yang digunakan sebanyak 15 ekor. Sampel yang digunakan terdistribusi dalam tiga genotipe (5 CC, 5 CT dan 5 TT). Penilaian komponen lemak meliputi: (1) Kandungan kolesterol total dan Kandungan Trigeliserida. Pemeriksaan kolesterol menggunakan metode: CHOD-PAP (Cholesterol Oxidase-Peroxidase Aminoantipyrine Phenol). Hasil penelitian menunjukkan bahwa kadar kolesterol total darah domba Padjajaran berada pada kisaran normal dan keragaman gen DGAT1 tidak berpengaruh nyata terhadap kadar kolesterol darah. Dari ketiga genotype DGAT, menunjukkan kelompok CC memiliki kadar kolesterol total paling rendah, dibandingkan kelompok lainnya, sedangkan kadar trigliserida terendah didapatkan pada genotype TT, namun tidak berbeda nyata dibandingkan dengan genotype CC dan CT. Kata-kata kunci: domba Padjadjaran, gen DGAT1, kolesterol Abstract The study was conducted to determine the effect of DGAT1 gene diversity on Padjadjaran sheep to cholesterol and triglyceride levels. The sheep used in this study is a 1.5-year-old Padjadjaran sheep, which has a specific genotype based on the DGAT1 gene. Total sample of sheep that used as many as 15 tail. The samples used were distributed in three genotypes (5 CC, 5 CT and 5 TT). Assessment of fat content are total cholesterol and Trigeliserida.,using cholesterol method: CHOD-PAP (Cholesterol Oxidase-Peroxidase Aminoantipyrine Phenol). The results showed that total DGAT1 did not significantly affect to blood cholesterol level. Of the three DGAT genotypes, the CC group had the lowest total cholesterol levels, compared to the other groups, while the triglyceride levels were low in the TT genotype, but not significantly different from the CC and CT genotypes. Keywords : Padjadjaran sheep, DGAT1, Choleseterol


2018 ◽  
Vol 16 (1) ◽  
pp. 1 ◽  
Author(s):  
AZRUL HILDAN SAFRIZAL

<p>The pattern and lifestyle of today's society with the presence of an interner facility makes people spend more time sitting out than on exercise and increased consumption of high-fat foods may increase the risk of cardiovascular disease. An effective therapy is needed in preventing the occurrence of cardiovascular disease. Hyperbaric oxygen now starts to develop for the treatment of several diseases, which in turn can increase the gene forming antioxidant enzymes and ROS. To determine effect of hyperbaric oxygen therapy on total cholesterol levels of wistar white rats (Rattusnovergicus) induced bye high fat. The study was carried out in an expeative post test only group control of three groups. One group is given standard feed. All groups induced high-fat diet and standard feed. Of the two groups induced, one group was given hyperbaric oxygen therapy with a dose of 3 x 30 minutes for six days on day 7 at a blood test to determine total cholesterol levels<strong>. </strong>One way Anova parametric statistic test showed that p = 0.007 &lt; α proved hypothesis that hyperbaric oxygen therapy giving effect to total cholesterol level of white mice of jantangalurist rings induced by high fat diet. Total cholesterol was significantly different between K (-) and K (+) and between K (-) and P. It was found that hyperbaric oxygen therapy had an effect on total cholesterol level dose of 3x30 minutes for six days.</p>


2017 ◽  
Vol 3 (2) ◽  
pp. 72
Author(s):  
Gusnita Darmawati

<p>Penelitian ini membangun suatu sistem pakar untuk menentukan menu makanan sehat berdasarkan golongan darah dan tingkat kadar kolesterol pasien dengan metode Forward Chaining. Tujuan untuk membantu orang awam dalam menentukan menu makanan sehat untuk pasien kolesterol. Sistem ini menganalisa masalah penentuan menu makanan sehat berdasarkan golongan darah dan tingkat kadar kolesterol pasien. Hasil yang diperoleh dari sitem pakar ini adalah berupa informasi makanan sehat yang akan dikonsumsi oleh pasien kolesterol dengan jenis golongan darah dan tingkat kadar kolesterol yang berbeda. Analisa dilakukan dengan cara mengetahui jenis golongan darah dan tingkat kadar kolesterol pasien yang ditampilkan oleh program sistem pakar ini, rancangan sistem ini menggunakan inference forward chaining, dengan implementasi sistem menggunakan sistem database Microsoft Office Access dan bahasa pemrograman Visual Basic 6.0. Dari rancangan aplikasi sistem pakar yang dibuat, maka orang awam yang memderita kolesterol dapat menentukan menu makanan sehat untuk di konsumsi berdasarkan golongan darah dan tingkat kadar kolesterol dengan menjalankan aplikasi sistem pakar.</p><p><em><br /></em></p><p><em><em>This study builds an expert system to determine the healthy food menu based on blood type and cholesterol levels of patients with Forward Chaining method. The goal is to help the layman in determining a healthy diet for cholesterol patients. This system analyzes the problem of determining healthy food menu based on blood group and patient cholesterol level. The results obtained from this expert system is in the form of healthy food information that will be consumed by cholesterol patients with the type of blood group and different cholesterol levels. From the design of expert system applications created, the layman who memderita cholesterol can determine the healthy diet to be consumed by blood type and cholesterol level by running an expert system application.<br /> <br /> </em></em></p>


Antioxidants ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 538
Author(s):  
Vita Maria Marino ◽  
Teresa Rapisarda ◽  
Margherita Caccamo ◽  
Bernardo Valenti ◽  
Alessandro Priolo ◽  
...  

Hazelnut peel (HNP), a by-product from the chocolate industry, is considered to be a suitable ingredient to be included in the diet of ruminants. This study aimed to evaluate the effect of feeding dairy ewes with a diet containing HNP on ripened cheese quality, including fatty acid (FA) profile, cholesterol, and tocopherol content, as well as stability during storage under commercial conditions. In total, 10 experimental cheeses were produced with bulk milk obtained from ewes fed a commercial concentrate (C group; n = 5) or a concentrate containing 36% HNP in dry matter (HNP group; n = 5). After 40 days of aging, each cheese was sub-sampled into three slices: one was analyzed immediately (C0 and HNP0), and the other two were refrigerated and analyzed after seven days (C7 and HNP7) and 14 days (C14 and HNP14), respectively. Compared to C, HNP cheese had more than twice as many tocopherols and mono-unsaturated FA and respectively 38% and 24% less of cholesterol and saturated FA. Tocopherols and cholesterol levels remained rather stable up to 14 days of storage regardless of the experimental group, suggesting no cholesterol oxidation. Therefore, the inclusion of HNP in ewe diets could be a valid resource to produce cheese with a healthier lipid profile and higher tocopherols content.


PEDIATRICS ◽  
1992 ◽  
Vol 90 (1) ◽  
pp. 80-86 ◽  
Author(s):  
David S. Freedman ◽  
Tim Byers ◽  
Karen Sell ◽  
Sarah Kuester ◽  
Eva Newe1l ◽  
...  

The relation of an initial measurement of serum total cholesterol to subsequent levels over a (mean) 13-month interval was examined in a multiracial (white, Hispanic, American Indian, and black) sample of 1680 one- to four-year-olds. Although the relation of the initial level to the final measurement (r = .54) did not vary by race, sex, relative weight, or changes in relative weight, the association increased with age at the time of the initial measurement (eg, r .64 among 4-year-olds). Based on the initial and final total cholesterol determinations, the within-person standard deviation was 21 mg/dL and the coefficient of variation was 13%. Although the final total cholesterol level was within 5 mg/dL of the initial level for 18% of the children, the two determinations differed by ≥25 mg/dL for about 35% of the children and by ≥50 mg/dL for about 8%. Of the 149 children who had an initial cholesterol level ≥200 mg/dL, 34% (about five times the expected number) had a follow-up level that was similarly elevated whereas 25% had a subsequent measurement below 170 mg/dL. The results indicate that although an initial cholesterol level in early life is moderately predictive of subsequent levels, it may be difficult to interpret a single total cholesterol determination because of substantial within-person variability.


Sign in / Sign up

Export Citation Format

Share Document