Antidiarrhoeal Potential of various Solvent Extracts of Achyranthes aspera against three diverse diarrhoeal animal models

2021 ◽  
pp. 4173-4177
Author(s):  
Syed Sagheer Ahmed ◽  
Chandra Prakash K ◽  
Saba Tabassum ◽  
Noor Salma ◽  
Ahalya Devi K H
Keyword(s):  
Animal Models ◽  
Herbal Medicines ◽  
Health Issues ◽  
Severe Dehydration ◽  
Major Health ◽  
Achyranthes Aspera ◽  
Synthetic Drugs ◽  
The People ◽  
Suitable Form ◽  
Natural Drugs

Diarrhoea is a condition characterized by a variation in the bowel movement. It is one of the major health issues in developing countries. Its severity is more in children’s. Diarrhoea causes severe dehydration and some time it may lead to death. Globally, over 5 million children’s are dying each year because of diarrhoea. In the present scenario, herbal medicines are used by the people in a wider range because of its safety as compared to synthetic drugs. So it is very crucial to identify and investigate available natural drugs for treating diarrhoea. Hence, the present study endeavor the evaluation of antidiarrhoeal activity of Achyranthus aspera. The anti-diarrhoeal activity was performed by using different animal models like castor oil-induced diarrhoea, prostaglandin-E2 induced enteropooling and gastrointestinal motility test. All the extracts of Achyranthus aspera showed considerable antidiarrhoeal activity in all the three animal models by reducing diarrhoeal episodes. The findings of the present investigation revealed the significant antidiarrhoeal property of Achyranthes aspera. Hence this plant can be used in the suitable form as an alternative to available synthetic antidiarrhoeal medicines which are not completely safe. Thus the adverse effects of synthetic drugs can be minimized by reducing its use.

Rheumatoid Arthritis: History, Stages, Epidemiology, Pathogenesis, Diagnosis and Treatment

2017 ◽  
Vol 9 (02) ◽  
Author(s):  
Abeer Fauzi Al-Rubaye ◽  
Mohanad Jawad Kadhim ◽  
Imad Hadi Hameed
Keyword(s):  
Rheumatoid Arthritis ◽  
Medicinal Plants ◽  
Systemic Disease ◽  
Modern Medicine ◽  
Whole Body ◽  
Internal Organs ◽  
Synthetic Drugs ◽  
Relieve Pain ◽  
Medicinal Treatment ◽  
Natural Drugs

The pharmacological mechanisms of the medicinal plants traditionally used for RA in Persian medicine are discussed in the current review. Further investigations are mandatory to focus on bioefficacy of these phytochemicals for finding novel natural drugs. Rheumatoid arthritis is chronic, progressive, disabling autoimmune disease characterized by systemic inflammation of joints, damaging cartilage and bone around the joints. It is a systemic disease which means that it can affect the whole body and internal organs such as lungs, heart and eyes. Although numbers of synthetic drugs are being used as standard treatment for rheumatoid arthritis but they have adverse effect that can compromise the therapeutic treatment. Unfortunately, there is still no effective known medicinal treatment that cures rheumatoid arthritis as the modern medicine can only treat the symptoms of this disease that means to relieve pain and inflammation of joints. It is possible to use the herbs and plants in various forms in order to relieve the pain and inflammation in the joints. There are so many medicinal plants that have shown anti rheumatoid arthritis properties. So the plants and plant product with significant advantages are used for the treatment of rheumatoid arthritis. The present review is focused on the medicinal plants having anti rheumatoid arthritis activity

scholarly journals Nephrotoxicity of Herbal Products in Europe—A Review of an Underestimated Problem of Nephrotoxicity of Herbal Products

2021 ◽  
Vol 22 (8) ◽  
pp. 4132
Author(s):  
Katarzyna Kiliś-Pstrusińska ◽  
Anna Wiela-Hojeńska
Keyword(s):  
Kidney Diseases ◽  
Herbal Medicines ◽  
Kidney Injury ◽  
Herbal Products ◽  
Chronic Kidney Diseases ◽  
European Origin ◽  
Synthetic Drugs ◽  
The Many ◽  
Pharmacologically Active ◽  
Traditional Chinese Herbal Medicines

Currently in Europe, despite the many advances in production technology of synthetic drugs, the interest in natural herbal medicines continues to increase. One of the reasons for their popular use is the assumption that natural equals safe. However, herbal medicines contain pharmacologically active ingredients, some of which have been associated with adverse effects. Kidneys are particularly susceptible to injury induced by toxins, including poisonous constituents from medicinal plants. The most recognized herb-induced kidney injury is aristolochic acid nephropathy connected with misuse of certain Traditional Chinese herbal medicines. Data concerning nephrotoxicity of plant species of European origin are scarce. Here, we critically review significant data of the nephrotoxicity of several plants used in European phytotherapy, including Artemisia herba-alba, Glycyrrhiza glabra, Euphorbia paralias, and Aloe). Causative mechanisms and factors predisposing to intoxications from the use of herbs are discussed. The basic intention of this review is to improve pharmacovigilance of herbal medicine, especially in patients with chronic kidney diseases.

scholarly journals Spirituality and Conflict in Healthcare: The History of the Canadian Baptists and Medical Mission in Orissa, 1900–1970

Histories ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 69-84
Author(s):  
Tiasa Basu Roy
Keyword(s):  
Religious Identity ◽  
Well Being ◽  
Word Of God ◽  
Health Issues ◽  
Medical Mission ◽  
The People ◽  
Medical Facilities ◽  
History Of ◽  
Ganjam District ◽  
Positive Results

It was from the middle of the eighteenth century that discussions regarding the strategies taken up by the Protestant missionaries to propagate the Gospel generated the issue of healthcare and medical facilities among people in India. Medical mission, which hitherto was not considered, started to gain importance and reaped positive results in terms of curing individuals and its trustworthiness among tribes residing in the frontier regions. However, this developed a separatist religious identity among the population, which apparently did not appear lethal, but later culminated in the fragmentation and impeachment of solidarity among the adivais (tribal) and vengeance from the Hindu population. This article will show how the Canadian Baptist Mission, with its primary aim of spreading the Kingdom of God among the tribal Savaras in the Ganjam district of Orissa, undertook measures for serving health issues and provided medical facilities to both the caste Oriyas and the tribal Savaras. Although medical activities oriented towards philanthropy and physical well-being, medical mission was not limited to healing illness and caring for all, but also extended to spreading the word of God and influencing the people to embrace Christianity as well, which invited political troubles into the region.

Schistosomiasis in Children in the Philippines: Beyond Health Issues

2017 ◽  
Vol 12 (04) ◽  
pp. 238-248
Author(s):  
Mario Torres ◽  
Hazel Luyon-Tabo ◽  
Steven Salibay ◽  
Cristina Cabanacan-Salibay
Keyword(s):  
Preventive Measures ◽  
The Philippines ◽  
Health Issues ◽  
Major Health Problem ◽  
Major Health ◽  
Factors Associated ◽  
Research Findings ◽  
Effects On Children ◽  
Mode Of Transmission ◽  
The Government

AbstractThis article aims to discuss the issues about Schistosoma japonicum infection in the Philippines based on the research findings of previous studies. This includes reviews about the nature of schistosomiasis, with emphasis on its effects on children. The review also discusses the mode of transmission of the parasite, etiology, and epidemiology, and relates these factors to the persistence of S. japonicum as a major health problem in the Philippines. The efforts, preventive measures, and recommended actions of the government are also mentioned and have been taken into consideration in strengthening the eradication measures against S. japonicum. This review further analyzes the risk factors associated with the infected individuals. Some measures and practices that may contribute to the prevention of S. japonicum infection are highlighted.

Indian medicinal plants with antidiabetic potential: An overview

2021 ◽  
pp. 2328-2335
Author(s):  
Monika Sahu ◽  
Vinod Kumar ◽  
Veenu Joshi
Keyword(s):  
Diabetes Mellitus ◽  
Medicinal Plants ◽  
The Body ◽  
Therapeutic Drug ◽  
Major Health ◽  
Synthetic Drugs ◽  
Comprehensive Information ◽  
Chronic Disorders ◽  
The Rich ◽  
Indian Medicinal Plants

Diabetes Mellitus is the most prevalent metabolic disorder which has made it a major health threat worldwide. The available synthetic drugs for the cure of Diabetes mellitus are associated with high cost, various side effects and several limitations. Medicinal plants are the rich depots of the phytochemicals which can be useful for the treatment of chronic disorders. These plants are the better alternative to chemical drugs causing less or no harm to the body. Several plants are traditionally known for their antidiabetic properties but the detail investigation of their active molecules is required in order to be developed as therapeutic drug. Therefore, the present review aims to provide comprehensive information on various Indian medicinal plants, their constituents and mechanism of action for the cure of diabetes mellitus.

A comprehensive review on the medicinal importance; biological and therapeutic efficacy of Lagenaria siceraria (Mol.) (bottle gourd) Standley fruit

2021 ◽  
Vol 21 ◽  
Author(s):  
Muhammad Zahoor ◽  
Muhammad Ikram ◽  
Nausheen Nazir ◽  
Sumaira Naz ◽  
Gaber El-Saber Batiha ◽  
...  
Keyword(s):  
Herbal Medicines ◽  
High Water ◽  
Bottle Gourd ◽  
Herbal Remedies ◽  
Lagenaria Siceraria ◽  
Synthetic Drugs ◽  
Domestic Plant ◽  
Phytochemical Constituents ◽  
Cucurbitaceae Family ◽  
Water Contents

: Herbal remedies have been employed for the treatment and management of different diseases for ages. Herbal medicines are a promising choice over modern synthetic drugs because of their low side effects and are thus considered safe and effective in treating human diseases. Lagenaria siceraria (Mol.) Standley fruit (Bottle gourd) belongs to the Cucurbitaceae family that has been used in a different system of traditional medication to treat various diseases. This is a domestic plant that provides food as well as medication. This vegetable has low caloric values and high water contents. The edible portion of it contains phytochemicals like vitamins, proteins, choline, minerals, terpenoids, flavonoids etc. Several bioactive compounds have been isolated from L. siceraria, including triterpenoids, sterols, cucurbitacins, flavones, C-glycosides and β-glycosides. Researchers have evaluated various parts of this plant viz., fruit, root, flowers, and leaves for pharmacological activities like antianxiety, antidepressant, diuretic, antimicrobial, cytotoxic, antihyperlipidemic, cardioprotective, analgesic, anti-inflammatory, anthelmintic, anti-hyperglycemic, antihepatotoxic, anti-urolithiatic, antistress, antiulcer, anticancer, hepatoprotective, anthelmintic, immunomodulatory, and antioxidant. In this review, an attempt has been made to explore its phytochemical constituents, traditional, medicinal, and pharmacological uses to highlight the therapeutic importance of this well-known plant. This would be helpful in reviving its importance and highlight its several promising aspects to encourage researchers for further research on L. siceraria.

Study of Mental Disorder Prediction Model approaches its issues and Challenges

2021 ◽  
Vol 23 (07) ◽  
pp. 831-840
Author(s):  
Avani S Bhuva ◽  
◽  
Dr. Dhirendra Mishra ◽  
Keyword(s):  
Mental Disorders ◽  
Mental Disorder ◽  
Health Issues ◽  
Human Beings ◽  
Major Health ◽  
The World ◽  
Different Types ◽  
Prediction Systems ◽  
Voice Modulation ◽  
Society Today

Mental disorder is becoming one of the major health issues in society today. (WHO) depression will be the leading mental disorder all over the world by 2030. The timely prediction of such disorders is very essential for maintaining the health of human beings. These mental disorders are associated with different symptoms, some of these symptoms are visible in the form of facial expressions, gestures, change in voice modulation, etc. and some of them even cannot be noticed by naked eyes. Therefore, it is highly important to collect appropriate verbal and non-verbal symptom details about any individual along with using best-suited algorithms for accurate prediction using information technology. This paper explores different types of such symptoms associated with different types of mental disorders, their causes, and existing prediction-based solutions. The paper further presents the critical analysis of these aspects and proposes usages of biometrics-based traits for building better prediction systems for mental disorders.

scholarly journals ON THE NEED TO DEVELOP AND IMPLEMENT IN THE TERRITORY OF THE KRASNODAR TERRITORY A PROJECT OF A STANDARD ELECTRONIC PLATFORM FOR MONITORING PUBLIC OPINION ON HEALTH ISSUES IN THE MUNICIPALITY

2021 ◽  
Vol 37 (1) ◽  
pp. 43-48
Author(s):  
S.А. Kuemzhieva ◽  
◽  
V.V. Goncharov ◽  
D.D. Oblogin ◽  
◽  
...  
Keyword(s):  
Public Opinion ◽  
Individual State ◽  
Health Issues ◽  
Public Authorities ◽  
The Public ◽  
Constitutional Principle ◽  
Constant Control ◽  
The People ◽  
Goals And Objectives ◽  
Municipal Level

The article is devoted to the study of the need to develop and implement on the territory of the Krasnodar Territory a project of a standard electronic platform for monitoring public opinion on health issues in the municipality. The authors substantiate the position that the powers delegated by the people to the public authorities need constant control by the public. Without public control, there is a risk of appropriation of power, usurpation of power by individual state authorities and their officials. The mechanism of feedback between the authorities and the people, one of the elements of which is the monitoring of public opinion, plays an important role in the implementation of the constitutional principle of democracy. At the same time, it is important to monitor public opinion on local issues at the municipal level, since these issues affect the vast majority of the country's population. A significant segment of local issues is somehow related to the organization and functioning of health care institutions and the provision of medical services to the population. In this regard, it seems necessary to develop and implement in the territory of the Krasnodar Territory a project of a standard electronic platform for monitoring public opinion on health issues in the municipality. The article analyzes the goals and objectives of this project, examines the main problems associated with its formation and implementation, justifies the main stages of project preparation, as well as a list of measures to improve regional legislation that will contribute to the implementation of this project. The paper uses a number of methods of scientific research, in particular: the methods of induction; deduction; classification; statistical; sociological; comparative-legal; historical; formal-logical.

scholarly journals Ethno Botanical Studies of District Dera Ghazi Khan, Province Punjab, Pakistan

2020 ◽  
Author(s):  
Tahira Aziz Mughal ◽  
Hamna Yasin ◽  
Zubaida Yousaf ◽  
Ismat Naeem Naeem
Keyword(s):  
Medicinal Plants ◽  
Rural Areas ◽  
Neurological Diseases ◽  
Herbal Medicines ◽  
Climatic Conditions ◽  
Structured Interviews ◽  
Medicinal Uses ◽  
Plant Parts ◽  
Floral Diversity ◽  
Natural Drugs

Abstract Background The chief aim of this study was to enlist the Ethnobotanical uses of plants in Dera Ghazi Khan, Punjab, Pakistan. Due to unique geographical and climatic conditions, Pakistan has a great floral diversity. Plants have been used by the indigenous people for treatment of different ailments since long. They are still dependent on the plants for their domestic purposes. Moreover, plants are used as first aid to treat diverse ailments such as hepatic disorders, cardiac diseases, neurological diseases, anticancer, respiratory diseases, ENT problems, gynecological problems etc. The traditional uses of medicinal plants lead to the discovery of natural drugs. This is first quantitative ethno medicinal documentation of medicinal plants in Dera Ghazi Khan. Punjab, Pakistan. Methods This ethno botanical information was collected from about 200 informants including male and female. Sample size was determined by statistical formula. The informative data was based on semi-structured interviews, group discussions, Questionnaire and field visits. Then the data was analyzed by applying different quantitative indices such as Informant Consent Factor (ICF), Use value (UV), Relative Frequency of Citation (RFC) and the Fidelity level (FL). Results Almost 185 plants belonging to 52 families were reported. Most-frequently cited families were Astreaceae (20 species) and Solanaceae (10 species). The most dominant life form was herbs (51%). The most-used plant parts were leaves (68%), followed by whole plant (65%), Most common mode of administration is extraction (50%). Generally herbal medicines were acquired from fresh plant material. Many species were reported with their different medicinal uses as has been reported in literature. Conclusions This ethno botanical documentation revealed that the plants are still used by natives of rural areas in their day-to-day lives. This study provides basis for the conservation of local flora. Plants with high ICF, UV and FL can be further used for phytochemical and pharmacological studies. This documentation could provide baseline information which can be used to develop new plant-based commercial drugs.

scholarly journals Strategies and Persuasive Appeals in the Public Service Messages about Health Issues on Pakistani Television Channels

2020 ◽  
Vol V (III) ◽  
pp. 54-72
Author(s):  
Qaisar Khan ◽  
Syed Inam Ur Rahman ◽  
Amna Nudrat
Keyword(s):  
Public Service ◽  
Heat Stroke ◽  
Calcium Deficiency ◽  
Health Issues ◽  
Major Health ◽  
The Public ◽  
Emergency Situations ◽  
Precautionary Measures ◽  
Aida Model

The study analyses strategies and persuasive appeals in the public service messages aired on Pakistani TV channels during 2016-2018, that measures the effects of PSMs on audience behaviour. The PSMs fails to deliver messages due to dissimilar socio-economic backdrop and scope of the audience understanding. The purposive sampling of six selected PSM is on the bases of health themed PSM’s. Objective is to investigate the characteristics of ads, role of the message, major health issues, sources of the message and appeals. The AIDA model, persuasion theory and social responsibility theory used to filter the textual analysis of the selected PSMs. It was found that the PSMs presented health issues while using celebrity endorsement and persuasive message appeals as persuasive techniques. The PSMs such as breast cancer persuaded women for self-care, calcium deficiency PSM to calcium intakes, heat stroke PSM to precautionary measures during emergency situations, the malnutrition PSM to women healthy diet during pregnancy. The study recommends that advertisers, producers and TV channels should adopt audience perception based important strategies for social welfare, while the state must promote them.

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