Histopathological alterations in the reproductive tract of male dogs with Canine Visceral Leishmaniasis

Dogs are considered the main domestic host of Leishmania infantum. The transmission between vertebrate hosts normally occurs during blood feeding of Lutzomyia sp., a genus of phlebotomine sand flies. However, other forms of transmission without a vector have been reported. Presence of amastigotes of Leishmania sp. in different organs can cause several pathologies depending on the immune status of the host and the parasite load. The aim of this study was to evaluate histopathological changes in the reproductive tract of male dogs. Samples of testes, epididymis, and prostate gland were collected from 70 animals that were grouped according to serology test results for visceral leishmaniasis and clinical symptoms. Three experimental groups were formed based on serological results and clinical presentation: asymptomatic, symptomatic and control. Prostatic changes were seen regardless of the serological results; however, the changes were more severe in symptomatic animals. In the testes and epididymis, lesions such as interstitial infiltrate, degeneration, and fibrosis were seen more frequently and were more severe in positive animals when compared to the control group. These results demonstrate that dogs infected with Leishmania sp. can develop nonspecific changes in the reproductive tract, which are more severe in symptomatic animals.

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Significance of Stabilometry for Assessing Postoperative Body Sway in Patients with Cervical Myelopathy

Asian Spine Journal ◽

10.4184/asj.2017.11.5.763 ◽

2017 ◽

Vol 11 (5) ◽

pp. 763-769 ◽

Cited By ~ 7

Author(s):

Shinji Tanishima ◽

Hideki Nagashima ◽

Hiroyuki Ishii ◽

Satoru Fukata ◽

Toshiyuki Dokai ◽

...

Keyword(s):

Cervical Myelopathy ◽

Clinical Symptoms ◽

Japanese Orthopaedic Association ◽

Body Sway ◽

Control Group ◽

Cervical Laminoplasty ◽

Test Results ◽

Timed Up And Go ◽

Eyes Closed ◽

And Control

<sec><title>Study Design</title>Prospective study.</sec><sec><title>Purpose</title>To examine the changes in body sway using stabilometry in patients who underwent cervical laminoplasty for cervical myelopathy.</sec><sec><title>Overview of Literature</title>Although the patients of cervical myelopathy complain body sway there are few report to examine body sway objectively.</sec><sec><title>Methods</title>Patients who received treatment for cervical myelopathy between October 2010 and February 2013 were included. Twenty-one patients underwent cervical laminoplasty (myelopathy group). Body sway was assessed using stabilometry, wherein patients stood on a stabilometer with their eyes closed for 30 seconds. The Romberg ratio, outer peripheral area (OPA) with eyes closed (cm2), and total locus length per unit area (L/A) with eyes closed (/cm) were examined. Examinations were performed preoperatively (at baseline) and at 8 weeks postoperatively. Examination results of patients in the myelopathy group were compared with those of 17 healthy individuals (control group). Clinical symptoms were evaluated using the Japanese Orthopaedic Association scale score (JOA score) and the timed up and go (TUG) test.</sec><sec><title>Results</title>In the myelopathy and control groups, the mean baseline Romberg ratio, OPA, and L/A were 2.3±1.2, 8.9±5.5 cm2, and 14.2±5.3/cm and 1.4±1.0, 4.3±2.8 cm2, and 23.7±10.1/cm, respectively. Eight weeks after laminoplasty, only L/A showed significant improvement from baseline in the myelopathy group (23.2±10.1 to 16.8±7.9; <italic>p</italic>=0.03). The Romberg ratio and OPA showed improvement in the myelopathy group, but the changes were not statistically significant. JOA scores and TUG test results in this group significantly improved from baseline to 8 weeks after laminoplasty (12.7 to 13.4 and 10.8 to 8.0 seconds, respectively; both <italic>p</italic><0.05).</sec><sec><title>Conclusions</title>L/A is a useful parameter for measuring body sway to assess the recovery of body sway after laminoplasty.</sec>

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Effects of Mangosteen pericarp Extract to Clinical Improvements, The Plasma Level of IL-6 and Malondialdehyde in Acute Exacerbation of COPD Patients

Jurnal Respirologi Indonesia ◽

10.36497/jri.v38i3.6 ◽

2018 ◽

Vol 38 (3) ◽

pp. 164-172

Author(s):

Khilyatul Baroroh ◽

Suradi Suradi ◽

Ade Rima

Keyword(s):

Treatment Group ◽

Plasma Level ◽

Length Of Stay ◽

Acute Exacerbation ◽

Clinical Symptoms ◽

Control Group ◽

Chronic Obstructive ◽

Copd Patients ◽

Significant Difference ◽

And Control

Background: Amplification of inflammation in acute exacerbation of chronic obstructive pulmonary disease (COPD) increases inflammatory mediators and oxidative stress in the airways, pulmonary and systemic circulation that are characterized by increased plasma level of IL-6 and MDA, resulting in worsening of clinical symptoms. Xanthones in mangosteen pericarp have anti-inflammatory and antioxidant effects, potentially as an adjuntive therapy in acute exacerbations of COPD. Methods: The aim of this study was to determine the effect of mangosteen pericarp extract to clinical improvements, plasma level of IL-6 and MDA of acute exacerbation COPD patients. A clinical trial of experimental with pretest and posttest was conducted on 34 acute exacerbation of COPD patients in Dr. Moewardi Hospital Surakarta and Dr. Ario Wirawan Lung Hospital Salatiga from April until May 2016. The sample was taken by consecutive sampling. Subjects were divided by randomized double blind technique into the treatment group (n=17) received mangosteen pericarp extract 2x1100mg/day and control group (n = 17) received placebo. Clinical improvements were measured in CAT score and length of stay. CAT score, plasma level of IL-6 and MDA were measured on admission and at discharge. Length of stay based on the number of days of care in hospitals. Results: There was significant difference (p=0,011) towards decreased of IL-6 plasma level between treatment group (-2,17 ± 3,46 pg/ mL) and control group (+1,67 ± 6,81 pg/mL). There were no significant difference towards decreased of length of stay (p=0,34) between treatment group (4,12 ± 1,54 days) and control group (5,24 ± 2,49 days), towards decreased of CAT score (p=0,252) between treatment group (-19,18 ± 3,96) and control group (-18,24 ± 2,75), and towards decreased of MDA plasma level (p=0,986) between treatment group (+0,03 ± 0,36μmol/L) and control group (+0,35 ± 1,58). Conclusions: The addition of mangosteen pericarp extract 2x1100mg/day during hospitalization was significantly lowered plasma levels of IL-6, but were not significant in lowering the CAT score, shortening the length of stay, and reducing the increase in plasma level of MDA.

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The effect of 8-week thera-band exercises on male swimmers’ 100 m freestyle swimming performance

Journal of Human Sciences ◽

10.14687/jhs.v14i4.4825 ◽

2017 ◽

Vol 14 (4) ◽

pp. 3950 ◽

Cited By ~ 3

Author(s):

Ahmet Gönener ◽

Utku Gönener ◽

Ozan Yılmaz ◽

Tuğçe Horoz ◽

Deniz Demirci

Keyword(s):

Swimming Performance ◽

Training Programme ◽

Rank Test ◽

Control Group ◽

Study Group ◽

Test Results ◽

Signed Rank ◽

Post Test ◽

Signed Rank Test ◽

And Control

The aim of this study is to investigate 8 weeks Thera-Band trainings' effects on male swimmers' 100 m freestyle swimming performance.The study group is created by 20 (n = 20) licenced male athletes that had trained at least 3 days in a week and have been active in swimming sport at least 3 years in Gebze Genclerbirligi Swimming Club 20 (n = 20). Athletes were divided into experiment group (n = 10) and control group (n = 10) randomly. Training programme was applied to the study group for 55-60 minutes for 3 days on alternate days and times when the club does not have swimming training. 12 different Thera-Band trainings were applied for 40-45 mins and each set was 15 minutes.Mann-Whitney U test was used to analyze differences between groups and Wilcoxon signed rank test was applied for analyzing the differences of intra-groups. SPSS 21.0 Statistics package software was used for statistical analyzes. The results show that there are no significantly differences between experimental group's and control group's post test results. (p>0.05). Statistically significant differences are found as a result of intra-group comparison of the experimental group's pre-test and post-test results (p<0.05).Depending on the results obtained after reviewing the literature, it can be concluded that Thera-Band training is effective on the performance improvement of swimmers aged 13-15 years.

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Application Model of Pranic Healing Therapy for Emotional Stress Using Accurate Bio-Well GDV Camera

E3S Web of Conferences ◽

10.1051/e3sconf/201912505005 ◽

2019 ◽

Vol 125 ◽

pp. 05005

Author(s):

Cahyaning Puji Astuti ◽

Melyana Nurul Widyawati ◽

Suryono Suryono

Keyword(s):

Emotional Stress ◽

Controlled Trial ◽

Pharmacological Therapy ◽

The Body ◽

Control Group ◽

P Value ◽

Test Results ◽

Emotional Instability ◽

Before And After ◽

And Control

Pregnancy is a period of both hormonal and non-hormonal overall change in the body. Emotional instability is commonly experienced by women during this period. However, this somewhat complex issue is often not addressed optimally. Pharmacological therapies using CPZ and lithium are often administered, but they have effects for the body. Therefore, there is a need to administer non-pharmacological therapy that has minimum side effects. This research aims to increase the healthy energy within the body using Pranic Healing, which is measured by the Bio-Well GDV camera. This research employed the pretest-posttest method on two groups (treatment and control) using the Randomized Controlled Trial design. Pranic Healing therapy was performed for 30 minutes once a week for 3 weeks, while GDV measurement was performed once a week for 4 weeks. Paired t-test results for Pranic Healing on emotional pressure showed p-value of 0.0001 (<0.05) for posttest2 and p-value of 0.005 (<0.05) for posttest3. Meanwhile, the control group did not indicate any changes in emotional stress both before and after treatment. It is found that Pranic Healing as measured using a bio-well GDV camera is capable of improving health energy within the body by relieving emotional stress experienced in trimester III primigravida.

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A Pilot Study on Controlling Coronavirus Disease 2019 (COVID-19) Inflammation Using Melatonin Supplement

Iranian Journal of Allergy Asthma and Immunology ◽

10.18502/ijaai.v20i4.6959 ◽

2021 ◽

Author(s):

Zahra Alizadeh ◽

Nastaran Keyhanian ◽

Sara Ghaderkhani ◽

Simin Dashti-Khavidaki ◽

Raheleh Shokouhi Shoormasti ◽

...

Keyword(s):

Clinical Symptoms ◽

Intervention Group ◽

Control Group ◽

Low Light ◽

Reactive Protein ◽

Significant Difference ◽

Before And After ◽

And Control ◽

To Receive ◽

Chest Ct Scan

No effective antiviral drugs and vaccines are available for the treatment of patients with severe coronavirus 2019 (COVID-19). Therefore, available, safe, and inexpensive drugs and supplements such as melatonin are among the proposed options for controlling inflammation. We did a randomized, single-blind study in Imam Khomeini Hospital between June 30, 2020, and August 5, 2020. Mild to moderate COVID-19 patients aged 25-65 years were eligible to enter the study based on chest CT scan, clinical symptoms, and physician diagnosis. The intervention group was prescribed 6 mg of oral melatonin for 2 weeks, which consumed half an hour before bedtime every night in low light conditions. Clinical symptoms and C-reactive protein (CRP) were measured before and after treatment in the melatonin received and control (regular medications) groups. Among screened patients with COVID-19, 14 patients were assigned to receive melatonin, and 17 patients were considered as controls. A significant difference (p=0.005) between CRP 1 and CRP 2 levels (before and after using melatonin) was found in the melatonin group while this difference (p=0.069) was not significant in the control group. Also, the percentage of recovery (based on symptoms) in patients who took melatonin was higher than that of patients in the control group (85.7% VS 47.1%). The result of this study confirmed the effectiveness of melatonin in mild to moderate outpatients with COVID-19. More clinical trials on elderly, diabetic, obese patients and severe cases are suggested in future studies.

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Placental Growth Factor Levels in Preeclampsia Compared to Normal Pregnancy

Indonesian Journal of Obstetrics and Gynecology ◽

10.32771/inajog.v3i2.31 ◽

2015 ◽

pp. 76-80

Author(s):

Dumaria Situmorang ◽

Hermie MM Tendean ◽

John J Wantania

Keyword(s):

Blood Glucose ◽

Maternal Age ◽

Normal Pregnancy ◽

Maternal Blood ◽

Placental Growth Factor ◽

Hemoglobin Level ◽

Control Group ◽

Test Results ◽

Cross Sectional ◽

And Control

Objective: To identify and analyze the differences in the levels of PlGF in preeclampsia and normal pregnancy. Method: This was a cross-sectional observational qualitative study of PlGF in preeclampsia and normal pregnancy. The number of samples in case and control group was 30 in each groups. Result: We found that mean of maternal age in the preeclampsia group was 28.53 years and 25.23 years in the control group. Mean parity in preeclampsia and control group was 2.33 and 1.56, respectively. Mean hemoglobin level in preeclampsia and control group was 11.97 and 11.99, respectively. Mean maternal blood glucose level was 87.0 in the preeclampsia group, and 87.9 in the control group. In the preeclampsia group mean urea concentration was 16.45, while it was 22.78 in the control group. Mean creatinine level was 0.92 in the preeclampsia group and 0.64 in the control group. Mean SGPT and SGOT in the preeclampsia group was 23.36 and 21.97, while in the control group was 29.86 and 26.20. Test results showed that PlGF levels was significantly different between the preeclampsia and control group. Mean PlGF in the preeclampsia and control group was 42.10 and 452.33 respectively, with p

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Effect of acidulated phosphate fluoride application on microhardness of glass ionomer cement

Padjadjaran Journal of Dentistry ◽

10.24198/pjd.vol27no2.26675 ◽

2015 ◽

Vol 27 (2) ◽

Author(s):

Mohammad Azrul Izzudin ◽

Elin Karlina ◽

Ratna Indriyanti

Keyword(s):

Glass Ionomer Cement ◽

Hardness Test ◽

High Viscosity ◽

Control Group ◽

Distilled Water ◽

Test Results ◽

Glass Ionomer ◽

Significant Difference ◽

Experimental Laboratory ◽

And Control

Introduction: Acidulated phosphate fluoride (APF) gels are commonly used as preventive caries materials in paediatric dentistry while glass ionomer cements (GICs) are widely used as a restorative material. The purpose of this study was to determine the effect of acidulated phosphate fluoride application towards the microhardness of GIC. Methods: This study was an experimental laboratory study where ten specimens were prepared from high viscosity GIC, which was Fuji IX. Specimens were stored in 50 ml distilled water at first 24 hours at 37°C, and then specimens were divided into fluoride group which was immersed in 25 ml of 1.23 % APF gel and control group which was stored 25 ml distilled water for 24 hours at 37°C. The Micromet II Microhardness Tester, Buehler, IL, USA that was standardised for Vickers hardness test was used to test the specimens at 100-gram load. Data were analysed using the t-test comparison test. Results: The level of microhardness of the fluoride group (14.34) was much lower compared to the control group (43.21) with a highly significant difference (p<0.01). Conclusion: The application of 1.23% APF gel on high viscosity GIC reduces the microhardness level compared to the control group.

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Evaluation of permeability of root dentin after different irrigation protocols

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh170731193b ◽

2018 ◽

Vol 146 (9-10) ◽

pp. 492-497 ◽

Cited By ~ 1

Author(s):

Ljiljana Bjelovic ◽

Jelena Krunic ◽

Nikola Stojanovic ◽

Jelena Eric ◽

Tatjana Kanjevac

Keyword(s):

New Combination ◽

Control Group ◽

Scanning Electron Microscopy Data ◽

Test Results ◽

Dye Penetration ◽

Dentin Permeability ◽

Significant Difference ◽

Root Dentin ◽

Microscopy Data ◽

And Control

Introduction/Objective. This study was aimed at evaluating dentin permeability after irrigation with sodium hypochlorite (NaOCl) and final rinse with chlorhexidine (CHX), ethylenediamine tetraacetic acid (EDTA) + CHX, and new combination products: QMiX or MTAD. Methods. Roots of 60 maxillary incisors were randomly divided into five groups (n = 12) before instrumentation and irrigation with NaOCl according to the final irrigation regimen: CHX (2% CHX), EDTA + CHX (17% EDTA + 2% CHX), QMiX, MTAD, and control group (distilled water). After final irrigation, ten roots of each group were horizontally sectioned and dye penetration was evaluated in the coronal, middle, and apical thirds. Remaining samples were subjected to scanning electron microscopy. Data were analyzed with ANOVA/Tukey?s test. Results. Less dye penetration was found in CHX group compared with control as well as with QMiX and MTAD group in all thirds (p < 0.05). A significant difference between the control and EDTA + CHX, QMiX or MTAD group was observed only in the apical root third (p < 0.05). Conclusion. Dentin permeability was significantly reduced after final irrigation with CHX, but not after use of other final irrigation solutions, except in the apical third of the root canal.

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Application of Discovery Learning Model in Increasing Student Interest and Learning Outcomes

Jurnal Penelitian Pendidikan IPA ◽

10.29303/jppipa.v7i4.745 ◽

2021 ◽

Vol 7 (4) ◽

pp. 542-548

Author(s):

Rosnidar Rosnidar ◽

Yusrizal Yusrizal ◽

Mustafa Mustafa ◽

Susanna Susanna

Keyword(s):

Student Learning ◽

Learning Outcomes ◽

Learning Model ◽

Discovery Learning ◽

Control Group ◽

Student Interest ◽

Test Results ◽

Learning Models ◽

Learning Interest ◽

And Control

This research aims to find out the application of discovery learning models in increasing students' interest and learning outcomes in harmonic vibrational materials in MAN 4 Aceh Besar. The method in this study is quasi-experimentation with the design of a pretest-posttest control group. The instruments used are questionnaires and problems. The results showed that the average N-gain of student learning interest in the experimental class was 0.79 high category and control class 0.28 low category. The results of each experimental class indicator included a very positive category while the category control class was positive. Based on the results of the analysis of both classes, it can be concluded that the average interest in student learning in the experimental class is more increased than in the control class, especially on indicators of student engagement. The average N-gain result of student learning outcomes in the experimental class obtained a score of 0.61 moderate categories, then in the control class obtained a score of 0.35 medium category. Based on the test results, the average of the two classes obtained significance scores of 0.000 < 0.05, meaning that there was a difference in the average learning outcome of students in experimental classes and control classes. This proves that the discovery learning model's application can improve students' learning outcomes higher than the discovery learning model in the control class. This study concludes that the application of discovery learning models can increase students' interest and learning outcomes in harmonic vibrational materials in MAN 4 Aceh Besar

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OPTIMALISASI POSISI JANIN MELALUI PRENATAL YOGA TERHADAP OUTPUT PERSALINAN DI PUSKESMAS WILAYAH KOTA CIREBON

Care Jurnal Ilmiah Ilmu Kesehatan ◽

10.33366/jc.v8i3.1816 ◽

2020 ◽

Vol 8 (3) ◽

pp. 396

Author(s):

Nurasih Nurasih ◽

Endang Nurrochmi

Keyword(s):

Intervention Group ◽

T Test ◽

Control Group ◽

P Value ◽

Test Results ◽

Chi Square ◽

Control Group Design ◽

Before And After ◽

Chi Square Test ◽

And Control

In Indonesia, Yoga is currently one of the most popular sports, not only for the general public but also for pregnant women. Many benefits can be obtained from prenatal yoga including the mother feeling comfortable and relaxed throughout pregnancy and during childbirth, training the pelvic floor muscles and perineum, keeping the body's muscles relaxed, balanced during childbirth, reducing stress, increasing and improving oxygen circulation to the body and fetus. . This study aims to determine the effect of prenatal yoga on optimizing fetal position on third trimester Primigravida maternal delivery output at Puskesmas Cirebon City. This research is a quasi-experimental research pre post control group design and only post control group design with T test and Chi Square test. Paired T Test results of the intervention group (mean difference = 3.111, P value = 0.000, control group (mean difference = 0.833, P value = 0.318). Independent T Test results obtained (average difference = -1.944, P value = 0.024), Chi Square test obtained a value of P = 0.73. There is a difference in the average anxiety before and after the intervention in the intervention group, there is no difference in average anxiety before and after the intervention in the control group. There is a difference in the average anxiety between the intervention and control groups. There is a difference in mean Long I stage between the intervention and control groups There was no effect of prenatal yoga on the type of labor.

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