scholarly journals Uji Aktivitas Antioksidan Ekstrak Etanol 70% Daun Matoa (Pometia pinnata) Terhadap Aktivitas ALT Dan AST Darah Tikus Putih Yang Diinduksi Karbon Tetraklorida (CCl4)

2021 ◽  
Vol 1 (1) ◽  
pp. 10-15
Author(s):  
Try Oktavia Djabar
Keyword(s):  

Antioksidan merupakan molekul yang mampu menstabilkan atau menonaktifkan radikal bebas agar tidak merusak sel. Senyawa kimia flavonoid mempunyai efek farmakologik sebagai antioksidan salah satunya adalah Daun matoa (Pometia pinnata). Penelitian ini bertujuan untuk melihat aktifitas antioksidan ekstrak etanol 70% daun matoa pada hati tikus putih jantan yang diinduksi CCl4. Perlakuan dilakukan selama 16 hari dengan 30 ekor tikus dibagi 6 perlakuan, kelompok KN dan KKN diberikan aquadest selama 5 hari; kelompok KKP diberi pembanding curcuma 81 mg/kg BB selama 10 hari; kelompok KE1, KE2 dan KE3 diberikan ekstrak etanol 70% daun matoa masing-masing KEI dosis I (100 mg/kg BB tikus), KE2 dosis II (200 mg/kg BB tikus) dan KE3 dosis III (400 mg/kg BB tikus) selama 10 hari. Semua kelompok kecuali KN di induksi dengan CCl4 dosis 0,05 mg/kg BW selama 5 hari. Pada hari ke-16, dilakukan pengambilan darah dan kemudian dilakukan pemeriksaan kadar Alanin aminotransferase (ALT) dan Aspartat aminotransferase (AST). Analisis statistik menggunakan One Way Anova. Peningkatan kadar ALT dan AST sudah dapat terlihat pada pemberian dosis 100 mg/kg BB dan aktivitas antioksidannya semakin meningkat pada dosis 400 mg/kg BB.

2019 ◽  
Vol 10 (2) ◽  
pp. 44-50
Author(s):  
Rinaldi Daswito ◽  
Rima Folentia ◽  
M Yusuf MF

One of the diseases that can be transmitted by flies is diarrhea. Green betel leaf contains essential oils, chavicol, arecoline, phenol, and tannins which function as plant-based insecticides. This study aimed to determine the effectiveness of green betel leaf extract (Piper betel) as a plant-based insecticide on the number of mortality of house flies (Musca domestica). The research was an experimental study used After Only Design used the One Way Anova test with a 95% confidence level. The samples used were 360 ​​house flies. Each treatment of 30 house flies with 4 repetitions and used three concentrations of green betel leaf extract (25%, 50%, 75%). The study was conducted at the Chemistry and Microbiology Laboratory of Health Polytechnic Tanjungpinang, while the location of the fly collection was at the Tokojo Garbage Collection Station in Bintan Regency. The number of mortality of house flies at a concentration of 25% was 81 heads (67.5%), 50% concentrations were 93 heads (77.5%), and at a concentration of 75% were 103 heads (85.83%). There was an effect of green betel leaf extract on the mortality of house flies (p-value 0.0001 <0.05) with the most effective concentration of 75%. Further research is needed to obtain a finished product utilizing green betel leaf extract as a vegetable insecticide, especially in controlling the fly vector. Need further research on the use of green betel leaf extract as a vegetable insecticide controlling the fly vector by taking into account the amount of spraying and the age of the fly.   Keywords: Green betel leaf extract , organic insecticide, houseflies


2018 ◽  
Vol 15 (2) ◽  
pp. 112
Author(s):  
MENTARI AMENDA SAPUTRI ◽  
HERIN SETIANINGSIH

<p class="Default">Penyakit kardiovaskular merupakan penyebab kematian nomor satu di dunia. Gaya hidup masyarakat terutama dalam mengkonsumsi diet yang tidak sehat dapat meningkatkan kadar LDL yang dapat menyebabkan  penyakit kardiovaskular. Rumput laut merah (<em>Kappaphycus alvarezii</em>)<em> </em>yang banyak dibudidayakan di Indonesia mengandung flavonoid dan triterpenoid yang diduga dapat menurunkan kadar LDL. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak rumput laut merah (<em>Kappaphycus alvarezii</em>) <em> </em>terhadap kadar LDL pada tikus putih (<em>Rattus norvegicus</em>) jantan galur Wistar yang diberi diet tinggi lemak. Penelitian ini adalah penelitian eksperimental murni laboratorik dengan rancangan penelitian <em>Post Test Control Group Design. </em>Sampel yang digunakan adalah 24 ekor tikus putih (<em>Rattus norvegicus</em>) jantan galur Wistar yang dibagi ke dalam tiga kelompok: kelompok yang diberi diet standar selama 28 hari (K1), kelompok yang diberi diet tinggi lemak selama 28 hari (K2), dan kelompok yang diberi diet tinggi lemak selama 28 hari dan pada hari ke-15 sampai hari ke-28 diberi ekstrak rumput laut merah (<em>Kappaphycus alvarezii</em>) dengan dosis 140mg/200grBB/hari (K3). Hasil analisis statistik <em>One Way Anova </em>menunjukkan bahwa terdapat perbedaan kadar LDL yang signifikan antara ketiga kelompok pada penelitian ini (p&lt;0,001). Kadar LDL pada K2 (=16,00±3,29) meningkat secara bermakna dibandingkan dengan K1 (=10,62±1,77). Sedangkan kadar LDL pada K3 (=6,88±2,42) menurun secara bermakna dibandingkan dengan K2. Dari hasil penelitian ini dapat disimpulkan bahwa ekstrak rumput laut merah (<em>Kappaphycus alvarezii</em>) berpengaruh terhadap kadar LDL darah pada tikus putih (<em>Rattus norvegicus</em>) jantan galur Wistar yang diberi diet tinggi lemak.</p><p><strong>Kata kunci</strong> : diet tinggi lemak, LDL, <em>Kappaphycus alvarezii</em></p>


2018 ◽  
Author(s):  
Asharaf Abdul Salam

<p>This paper undertakes a detailed analysis of 2010 Census Population and Household Tables (Final), to assess governorate wise variations in home ownership, type of living accommodations and housing infrastructure - material used for construction, electricity, water and sewage facilities.</p> <p>The data published by the Ministry of Economics and Planning in its “Population and Housing, 2010 Census” analyzed in detail using SPSS20, applying statistical methods such as, cross tabulations and chi-square; mean and standard deviation; and One-Way ANOVA. Governorates classified into small, medium and large, according to the number of Saudi persons, have been analyzed across 13 regions quantifying homeownership status. Further governorates are classified according to the percentage of owning homes in order to analyze the type of living accommodations, built up material of housing, source of electricity, water and sewage facilities. </p> <br>


2018 ◽  
Author(s):  
Asharaf Abdul Salam

<p>This paper undertakes a detailed analysis of 2010 Census Population and Household Tables (Final), to assess governorate wise variations in home ownership, type of living accommodations and housing infrastructure - material used for construction, electricity, water and sewage facilities.</p> <p>The data published by the Ministry of Economics and Planning in its “Population and Housing, 2010 Census” analyzed in detail using SPSS20, applying statistical methods such as, cross tabulations and chi-square; mean and standard deviation; and One-Way ANOVA. Governorates classified into small, medium and large, according to the number of Saudi persons, have been analyzed across 13 regions quantifying homeownership status. Further governorates are classified according to the percentage of owning homes in order to analyze the type of living accommodations, built up material of housing, source of electricity, water and sewage facilities. </p> <br>


Author(s):  
Hanny Tioho ◽  
Maykel A.J Karauwan

The minimum size of coral transplants, Acropora formosa, was assessed to support their survival and growth. For this, 150 coral fragments of different sizes (5, 10, 15 cm) were transplanted close to the donor colony. Their survivorship and growth were observed for 12 months. At the end of the observation time, 90% of 15 cm-transplanted coral fragments survived, while the others (10cm and 5 cm) did 86% and 82% respectively. The average growth rate of 5 cm-coral fragments was 0.860 cm/month, while 10 and 15 cm-fragments were 0.984 cm/month and 1.108 cm/month respectively. One-way ANOVA showed that there was significant difference (p<0.05) among the three (5, 10, 15 cm) transplant initial sizes in which the longest fragment size tended to survive longer than the smaller one.  However, the smaller transplants grew better than the bigger one, 10.318 cm/year (206%) for 5 cm-transplant, 11.803 cm/year (118%) for 10 cm-transplant, and 13.299 cm/year (89%) for 15 cm-transplant, respectively. Ukuran minimal fragmen karang Acropora formosa yang ditransplantasi diduga untuk mendukung ketahanan hidup dan pertumbuhannya. Untuk itu, 150 fragmen karang ditransplantasi ke lokasi yang berdekatan dengan koloni induknya.  Ketahanan hidup dan pertumbuhan semua fragmen karang yang ditransplantasi diamati selama 12 bulan.  Pada akhir pengamatan, 90% dari fragmen karang berukuran 15 cm yang ditransplantasi dapat bertahan hidup, sedangkan yang lainnya (ukuran 10 cm dan 5 cm) masing-masing sebesar 86% dan 82%.  Rata-rata laju pertumbuhan fragmen karang dengan ukuran awal 5 cm adalah 0,860 cm/bulan, sedangkan ukuran fragmen 10 dan 15 cm masing-masing adalah 0,984 cm/bulan and 1,108 cm/bulan. ANOVA satu arah menunjukkan adanya perbedaan yang nyata (p<0.05) antara ketiga ukuran fragmen yang berbeda, di mana ukuran fragmen karang yang lebih panjang cenderung mempunyai ketahanan hidup yang lebih baik. Namun demikian, ukuran transplant yang lebih kecil memiliki pertumbuhan lebih baik dibandingkan dengan ukuran yang lebih besar, yakni10,318 cm/tahun (206%) untuk transplant berukuran 5 cm, 11,803 cm/tahun (118%) untuk 10 cm, dan 13,299 cm/tahun (89%) untuk ukuran 15 cm.


Author(s):  
Laila Uthomah
Keyword(s):  

Abstrak Manusia secara hakiki merupakan makhluk sosial yang tidak mungkin dapat bertahan hidup seorang diri dan membutuhkan pergaulan dengan orang – orang lain. Sehingga manusia perlu mengembangkan sikap kooperatif serta berperilaku menolong terhadap sesamanya atau di dalam istilah psikologi disebut perilaku prososial. Perilaku menolong menunjukkan bahwa orang cenderung memiliki karakteristik menolong sesuai dengan peran gendernya. Hipotesis alternatif (Ha) dalam penelitian ini yaitu, “Ada perbedaan kecenderungan perilaku prososial ditinjau dari peran gender pada penumpang kereta api di Stasiun Cikini”. Jumlah sampel yang diambil 120 orang dan teknik pengambilan sampel menggunakan Accidental Sampling. Metode pengambilan data menggunakan skala kecenderungan perilaku prososial, dan peran gender yang mengacu pada penilaian skala Likert. Setelah dilakukan analisis data hipotesis menggunakan One Way Anova diperoleh nilai F sebesar 3,893 dengan taraf signifikansi 0,023 dan p


Author(s):  
Zuhendi Arifan Siagian ◽  
Habibah Wulandarena Hosaina ◽  
Mellisa Sim

Dewasa ini bahan antibakteri banyak di teliti, baik senyawa kimia ataupun alami untuk menghambat perkembangan bakteri. Ekstrak daun salam (Syzygium polyanthum) dan kitosan nanopartikel banyak menjadi bahan penghambat antibakteri ”Streptococcus mutans” yang adekuat, sehingga banyak peneliti mengembangkan bahan tersebut agar mendapatkan efek maksimal dari bahan antibakterinya. Penelitian ini memiliki tujuan untuk melihat peningkatan efek ekstrak daun salam - Kitosan Nanopartikel 1% terhadap pertumbuhan bakteri Streptococcus mutans. Proses maserasi di lakukan pada ekstrak daun salam kemudian konsentrasinya di ubah menjadi 50%, 75% dan 100%, pencampuran dengan kitosan nanopartikel 1% dengan perbandingan 1:1. Metode uji disc diffusion (Tes Kirby-Bauer) untuk melihat efektifitas antibakteri. Uji statistik one way ANOVA menunjukan angka yang signifikan p>0,05 dengan hasil ekstrak daun salam konsentrasi 100%, 75% dan 50% - kitosan naopartikel 1% dalam menghambat pertumbuhan bakteri Streptococcus mutans adalah 13,45 ± 0,2881 mm, 12,67 ± 0,2733 mm dan 11,52 ± 0,4070 mm. Maka ekstrak daun salam - Kitosan nanopartikel mempunyai efek antibakteri yang kuat terhadap bakteri “Streptococcus mutans” dari setiap grup penelitian yang di lakukan, efek tertinggi konsentrasi ekstrak daun salam 100% - nanopartikel kitosan 1% sebesar 13,45 mm.


Author(s):  
Ni Gusti Ayu Manik Ermayanti ◽  
I Gusti Lanang Oka ◽  
I Gede Mahardika ◽  
I Putu Suyadnya

This study was intended to determine the free testosterone levels and sperm quality of local rabbit that was given commercial feed supplemented cod fish liver oil.  The experiment design that was used in this research was Complete Random Design (CRD) with four experiments of feed, i.e. commercial feed without cod fish liver oil (R-0) as control, commercial feed + 1,5% cod fish liver oil (R-1), commercial feed + cod fish liver oil 3% (R-2), commercial feed + cod fish liver oil 4,5% (R-3). The each experiment included eight rabbits and feed experiment was given starting by 13 weeks to 26 weeks years old. The variable that observed was free testosterone level and sperm quality of local rabbit. The data that was obtained to be analyzed with One Way Anova and if its contrast was done more test with Duncan’s Multiple Range Test (DMRT). The result of this research was to show that supplementation of cod fish liver oil in commercial feed was to show the result that a real distinction of (P<0, 05) towards free testosterone level and sperm quality of local rabbit.


Author(s):  
Daniel Suter ◽  
Caio Victor Sousa ◽  
Lee Hill ◽  
Volker Scheer ◽  
Pantelis Theo Nikolaidis ◽  
...  

In recent years, there has been an increasing number of investigations analyzing the effects of sex, performance level, and age on pacing in various running disciplines. However, little is known about the impact of those factors on pacing strategies in ultramarathon trail running. This study investigated the effects of age, sex, and performance level on pacing in the UTMB® (Ultra-trail du Mont Blanc) and aimed to verify previous findings obtained in the research on other running disciplines and other ultramarathon races. Data from the UTMB® from 2008 to 2019 for 13,829 race results (12,681 men and 1148 women) were analyzed. A general linear model (two-way analysis of variance (ANOVA)) was applied to identify a sex, age group, and interaction effect in pace average and pace variation. A univariate model (one-way ANOVA) was used to identify a sex effect for age, pace average, and pace variation for the fastest men and women. In our study, pace average and a steadier pace were positively correlated. Even pacing throughout the UTMB® correlated with faster finishing times. The average pace depended significantly on sex and age group. When considering the top five athletes in each age group, sex and age group also had significant effects on pace variation. The fastest women were older than the fastest men, and the fastest men were faster than the fastest women. Women had a higher pace variation than men. In male competitors, younger age may be advantageous for a successful finish of the UTMB®. Faster male runners seemed to be younger in ultramarathon trail running with large changes in altitude when compared to other distances and terrains.


Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2509
Author(s):  
Žana Stanić ◽  
Ajka Pribisalić ◽  
Maria Bošković ◽  
Jasna Bućan Cvitanić ◽  
Kristina Boban ◽  
...  

The obesity pandemic has brought forth a scientific interest in food intake and sensory perception interactions. Olfactory perception and gustatory perception are very complex and under the influence of many factors, including the menstrual cycle. This study aims to clarify conflicting findings on the influence of the menstrual cycle on olfactory and gustatory perception. Women were assessed during four consecutive phases of one complete cycle (mid-follicular, ovulatory, mid-luteal, and late luteal phases (N = 21)), in contrast to women measured across the same phases belonging to two menstrual cycles (N = 29). Additional control groups were men (N = 17), postmenopausal women (N = 14), oral contraceptive users (N = 10), and women with an anovulatory cycle (N = 8). Olfactory threshold, odor discrimination, and identification were tested using the “Sniffin Sticks“ test kit. Suprathreshold intensity and hedonic ratings for sweet, salty, sour, and bitter solutions were assessed. One-way ANOVA and ANOVA for repeated measurements was applied in the analysis, along with linear and trigonometric data fitting and linear mixed models. Linear increases in olfactory discrimination, identification, and overall olfactory performance were observed only in women followed across a complete menstrual cycle. Compared to other groups, these women displayed a cyclic pattern characterized by a predilection for sweet solution; reduced distaste for salty and sour solutions; and increased intensity perception of salty, sour, and bitter solutions towards the end of the cycle. These results suggest that a distinct hormonal milieu of a complete menstrual cycle may be affecting both olfactory and gustatory perception.


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