scholarly journals Pharmacopeial Testing of Poly-Herbal Formulation for the Management of Diabetes Mellitus

Author(s):  
Farah-Saeed . ◽  
S. M. Alam ◽  
A. S. Memon

Diabetes mellitus is a global cause of morbidity and mortality. There is a continuous rise in the patients of diabetes in Pakistan. Many conventional and natural origin medicines are available for maintaining optimum blood sugar level. There is a need to carry out standardization of the natural origin medicine to authenticate their efficacy and safety. The objective of this research work was to carry out preliminary pharmacognostic, phytochemical, biological, pharmacological studies on poly-herbal formulation. The poly-herbal preparation was prepared and evaluated for the standard pharmacopeial tests. The results of the tests performed were found to be adequate to evaluate the poly-herbal formulation and may be used as reference standards in future for further studies.

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Niken Sukesi

Penyakit Diabetes Melitus dapat menyebabkan komplikasi yang sangat berat. Komplikasi dari Diabetes Melitus ini meliputi jantung iskemik, serebrovaskuler, gagal ginjal, ulkus pada kaki, gangguan penglihatan. Komplikasi yang paling sering terjadi adanya perubahan patologis pada anggota gerak bawah yang disebut kaki diabetik. Salah satu jenis olahraga yang dianjurkan dengan diabetes mellitus adalah senam kaki. Senam kaki merupakan latihan yang dilakukan bagi penderita DM atau bukan penderita untuk mencegah terjadinya luka dan membantu melancarkan peredaran darah bagian kaki. Penelitian ini bertujuan untuk menganalisis pengaruh senam kaki terhadap kadar gula darah pasien diabetes mellitus. Desain dalam penelitian ini adalah Quasy Eksperiment dengan rancangan Pre and Post Test Without Control. Teknik pengambilan sampel menggunakan Consecutive sampling. Alat pengumpul data yang digunakan instrument observasi senam kaki untuk menilai senam kaki, dan alat menilai kadar gula darah yaitu glucometer, kapas dan jarum. Rata-rata kadar gula darah sebelum dan setelah dilakukan senam kaki mengalami penurunan dan ada pengaruh kadar gula darah sebelum dengan sesudah dilakukan senam kaki pada pasien diabetes melitusKata Kunci: Senam Kaki, Kadar Gula Darah THE EFFECT OF GYMNASTIC FEET TOWARD THE BLOOD SUGAR LEVEL FOR THE DIABETICSDiabetes Mellitus causes the complication case. It concludes the heart iskemik, serebrovaskuler, cronic kidney disease, ulcus on the feet, and the impairment of sight. The complication often causes the changing of pathological in certain place such as feet. The one of recommended sport for diabetics is gymnastic feet. Gymnastic feet is an experience for diabetics or not in order to prevent the wound and launch the blood circulation. The research objective is to analyze the effect of gymnastic feet to blood sugar level for diabetics. The research design is using experiment quasy with pre and post test without control. It is using consecutive sampling as the sample of collecting technique, and using observation of gymnastic feet as the collecting data technique to assess the blood sugar level, those are glucometer, cotton, and needle. The average of blood sugar level is decrease after doing the gymnastic feet. Moreover, there is differences between after and before doing the gymnastic feet for diabetics.Key Words : Gymnastic Feet, Blood sugar level


Author(s):  
Dyah Marianingrum ◽  
Ibrahim ,

According to the 2017 International Diabetes Federation, the global prevalence rate of Diabetes Mellitus sufferers of 8.8% of the total population in the world from year to year shows an increase. The number of deaths that occurred as many as 4 million people in 2017. The western Pacific region including Indonesia has the highest mortality rate compared to all regions with a mortality rate of 1.3 million in adults. This shows the awareness of the sufferers of Diabetes Mellitus for routine check-ups to health centers is still lacking. According to the 2013 Basic Health Research, the prevalence of people with diabetes mellitus in Indonesia based on a diagnosis or symptoms of 2.1% increased from previous research of 1.1%. The prevalence of DM in Riau Islands Province increased from 0.8 to 1.5%. According to Batam City Health Office data in 2016, the incidence of Diabetes Mellitus in several Puskesmas with 3,724 visits, Botania Puskesmas was the third highest after Lubuk Baja and Balik Padang. This study used a survey method with a cross-sectional approach. The population in this study was Type 2 diabetes mellitus patients who examined themselves at the Botania Health Center in Batam City. Sampling using a purposive sampling technique with criteria established by researchers. The dependent variable in this study is blood sugar level because it is a diagnosis of diabetes mellitus while the independent variable is the measurement of waist circumference. Data analysis using the Spearman rank test. The results of the univariate analysis showed 73.7% of the majority of respondents had a high sugar level. Bivariate analysis with the Spearman Rank test, the results of the analysis found there is a relationship between waist circumference size and blood sugar levels (P-value = 0.341) with the direction of a positive relationship and the strength of the relationship is sufficient (r = 0.409). There is a significant relationship between waist circumference size and blood sugar level with sufficient strength of a relationship


2020 ◽  
Vol 5 (1) ◽  
pp. 16-24
Author(s):  
Carmelita Barros ◽  
Fitri Arofiati

ABSTRACT Diabetes mellitus (DM) in Indonesia is better known as diabetes and in Timor Leste DM known as Ra'an Midar has become a very serious health problem, and is the most common endocrine disease. Diabetes mellitus is a degenerative disease that is characterized by metabolic disorders or pancreatic damage so that the pancreas is unable to produce enough insulin to the maximum so that it can cause insulin deficiency in the body both absolute and relative can increase blood sugar levels or hyperglycemia. Data from the Dili District Health Office in 2018 showed that there were 2690 patients with diabetes mellitus, so that diabetic foot exercises were needed. The purpose of this study was to determine the effect of Tetum Language Diabetes Foot Gymnastic Education on Lower Circulation and Lower Blood Sugar Levels at the Saude Comoro Center, Dili, Timor Leste. Method : using the Pre-Experiment method. Independent variable: Education of Tetum Language Diabetes Foot Gymnastics Education, dependent variable: Circulation of Lower Extremity and Blood Sugar Level at a Time. Population 100 people, sample 28 people, sample technique: simple random, data collection: Examination of blood sugar levels, blood circulation, statistical tests: Wilcoxon Test. Results : Most respondents who had good blood circulation were 15 pre- test (53.6%) and 18 post-test (64.3%). And the majority of respondents whose blood sugar levels were good were 14 people pre-test (50.0%) and 20 people post test (71.4%). Based on the results of statistical tests using the Wilcoxon Signed Rank Test, the value of blood circulation is a significant level of 0.005 and the blood sugar level is at a significant level of 0,000. Conclusion : Conclusion there is the influence of Education on Tetun Language Diabetes Foot Gymnastics on Lower Extracurricular Circulation and Blood Sugar Levels At the Saude Comoro Center, Dili, Timor Leste.  Keyword: Leg exercise, lower extremity bloodd circulation, Blood sugar levels, Diabetes mellitus.


2021 ◽  
Vol 6 (2) ◽  
pp. 94
Author(s):  
Agus Sutiono ◽  
Dedy Purwito

Diabetes mellitus is one of cronical degenerative disease. The prevalence of sufferers continues to increase every year, one of the non-pharmacological therapies is exercise such as gymnastics prolanis DM and walking exercises to decrease the glucose level by the body muscles during the physical body. Objective this research is to find out the effectiveness of Prolanis and walking exercises in reducing blood sugar levels in DM patients type II. Method this study uses the Quasi experiment with pre and post with two group design. The study population was 92 DM patients type II with a sample of 82 people. Glucometer (Auto check blood glucose monitor) is used to collect the data. Wiloxon Test is used to analyze the statistical data. Results the research shows that the value of Prolanis Exercises (DM) is p=0.002 which means a significant influence on decrease of the sugar level of DM patients type II. Meanwhile the value of walking exercises is p=0.001. From the statistic test of WIlconxon Signed Rank Test, It obtained Z correlation = 7.886. It means that there is a significant correlation between Prolanis and walking exercises towards the decrease of blood sugar level of Diabetes Mellitus patients type II. Physical activities done regularly, measurably, and correctly are suggested to be considered as non-pharmacological therapies for Diabetes Mellitus patients type II to decrease blood sugar level. Keywords: Prolanis Exercises (DM), Walking, sugar blood level.


2018 ◽  
Vol 5 (12) ◽  
pp. 3858
Author(s):  
Divakara S. R. ◽  
Thrishuli P. B. ◽  
Bhavuray Teli

Background: Necrotizing fasciitis (NF) is a uncommon and serious infection involving the skin and subcutaneous tissues of lower and upper limbs, perineal area (Fournier’s gangrene), and the abdominal wall with high morbidity and mortality. Early diagnosis and aggressive treatment can reduce the mortality rate of NF. The objectives of this study are to study the etiolopathological, microbiological factors determining the outcome of necrotizing fasciitis.Methods: It is prospective study and was conducted in JSS Medical College and Hospital in October 2008 to October 2010. Total 50 patients diagnosed with necrotizing fasciitis were admitted to JSS Medical College and Hospital. Demographic data, type of co morbidities, site of infection, clinical features with microbiology and laboratory results, and outcomes of patients were analyzed.Results: Out of 50 patients there were 42 males and 8 females. Highest number of cases was found in the age group of 65-74 years among males, 55-64 years among females. The commonest site in the present study is lower limbs (74%). Diabetes mellitus was the commonest (76%) co morbidity. Beta hemolytic streptococci 22 (44%) was the highest to be isolated. In type I and Coagulase positive staphylococci 18 (36%) was the commonest organism isolated in type II necrotizing fasciitis. The significant risk factors were gender, comorbidties, hospital length of stay, and albumin level, leucocytosis, anemia, hypoalbumenia, low serum ferritin levels increase blood sugar levels. The mortality was 12% (8 patients).Conclusions: Patients with advance age, co-morbid conditions like diabetes mellitus, hypertension, peripheral vascular disease, osteomyelitis had high unexplained susceptibility to the disease and with a higher incidence in males. Thus, early recognition with a high index of clinical suspicion would definitely reduce both morbidity and mortality. It has gross morbidity and mortality if not treated in its early stages. Leucocytosis, anemia, hypoalbumenia, low serum ferritin levels, increase blood sugar levels were consistent findings seen in majority of the patients which resulted in increased morbidity.


2017 ◽  
Vol 8 (2) ◽  
pp. 53
Author(s):  
Dani Rosdiana

Prevalence of diabetes mellitus in Riau have reached 10,4 %, it’s higher than national pravelence. Hence, it’s needmore attention from physician. The important thing in managing DM is how to restrain controlled blood sugar level.The best parameter to evaluate controlled blood sugar level is level of HbA1c. Fasting blood glucose is one ofimportant component which determine HbA1c especially HbA1c more than 8,5%. There are some pharmacologyagent to decrease HbA1c level, and insulin is the most effective agent. Why physician needs insulin?It was caused by impairment of betha cell pancreas was directly propotional with DM progressiveness. Comprehensionand capability for using basal insulin are important to physician, not only for internist but also for general practinioner.As we know that general practinioner have a competency to manage DM without complication. Guidance for usingsimple and practical basal insulin is expected will facilitate physician to manage blood sugar level of DM patient.


Author(s):  
Asirotul Marifah Marifah

There are still many of our people who have never heard or even seen the shape of the Japanese ants, so sometimes people consume Japanese ants with different doses between people with each other and even some who consume Japanese ants are not appropriate doses because they want to get well soon. The purpose of research to know the relationship between consumption patterns of Japanese ants and blood sugar levels of people with diabetes mellitus. The design of this study is correlational analytic with crossectional approach. Variables of this research there are two that is the pattern of consumption of Japanese ants as an independent variable and blood sugar levels as the dependent variable. The population of this study was all patients with diabetes Mellitus who had suffered > 5 years who consumed Japanese ants in Grinting Village Karangjeruk Village Jatirejo Subdistrict Mojokerto regency as many as 10 respondents. in the sampling of researchers using total sampling technique. Data collection with an observation sheet of Japanese ant consumption and blood sugar level. The result of the research showed that most of the respondents consume Japanese ants regularly as much as 6 respondents (60%) and most respondents have blood sugar level in the normal category that is between 100-125 mg/dl as many as 6 respondents (60%). Consumption Japanese ants can routinely lower blood sugar levels of people with diabetes mellitus because ants contain enzymes that can keep blood sugar levels diabetics.


Author(s):  
Akshay S Jadhav ◽  
Pallavi S Kale ◽  
Vaishnavi N Pankade ◽  
Snehal A Kardule ◽  
Shubhangi B Hase ◽  
...  

Now days lot of diabetic medicine are available in market having chemical substance. They have lots of side effect but now days lot of anti diabetic medicines are available but sometimes they does not show effect on same patient. Their bodies does not stimulate B-pancreatic cells in bodies which are insulin production. To overcome this problems by using anti diabetic herbal formulation. It is effective, safe to use It maintain blood sugar level , Regulate the blood flow, It has anti diabetic , antioxidant , anticancer, anti microbial and antiinflammatory properties without any side effect.


2017 ◽  
Vol 4 (5) ◽  
pp. 1555
Author(s):  
Vinu Gopinath ◽  
S. Soundara Rajan

Background: Diabetes mellitus is a chronic disease which occurs either when the pancreas does not reproduce enough insulin, the hormone that regulates blood sugar level or when the body cannot effectively use the insulin it produces. Hyperglycemia or raised blood sugar level is a common effect of uncontrolled diabetes and over time leads to serious damage to many of the system of the body especially nerves and blood vessels. Diabetes mellitus has become the cause for growing public health concern in developing countries as it has been for a long time in most developed ones. The reason for increase in prevalence of diabetes mellitus in developing countries may include unhealthy life style, rapid westernization, poor knowledge, negative attitude and poor practice towards diabetes mellitus among general population. Objective of the study was to find out the knowledge, and awareness towards diabetes mellitus among diabetic foot ulcer patients attending in a tertiary care Centre.Methods: A cross sectional study was carried out in the surgical outpatient department of a tertiary care Centre. All diabetic foot ulcer patients attending surgical outpatient department for the period of two months was included. Juvenile diabetic patients, Type II diabetes mellitus patients with co morbidities are excluded.Results: Out of the 100-study participant’s majority are males (61%). 55% of the study participants are not aware of the major cause of diabetes mellitus. 92% of the population knew the accurate method of monitoring diabetes mellitus. 70.6% of people are aware of normal blood sugar level. 51% of people are aware of the complications of diabetes mellitus and 84.3% of people know the symptoms of diabetes mellitus. 68.6% of the population knew regular exercise can control diabetes mellitus yet only 50.8% of population exercise regularly.Conclusions: This study reflects that there is a need to improve diabetic knowledge among the patients which can be achieved through health education.


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