Fascinating Role of Silicon Nanoparticles to Mitigate Adverse Effects of Salinity in Fruit Trees: a Mechanistic Approach

Silicon ◽  
2022 ◽  
Author(s):  
Hafiza Muniba Din Muhammad ◽  
Asjid Abbas ◽  
Riaz Ahmad
Keyword(s):  
Adverse Effects ◽  
Silicon Nanoparticles ◽  
Fruit Trees ◽  
Mechanistic Approach

Regulation of microRNAs in Inflammation-Associated Colorectal Cancer: A Mechanistic Approach

2020 ◽  
Vol 20 ◽  
Author(s):  
Sridhar Muthusami ◽  
Ilangovan Ramachandran ◽  
Sneha Krishnamoorthy ◽  
Yuvaraj Sambandam ◽  
Satish Ramalingam ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Molecular Mechanisms ◽  
Colorectal Carcinogenesis ◽  
Model Systems ◽  
Necrosis Factor Alpha ◽  
Multi Stage ◽  
Mechanistic Approach ◽  
Tnf Α ◽  
Factor Alpha

: The development of colorectal cancer (CRC) is a multi-stage process. The inflammation of the colon as in inflammatory bowel disease (IBD) such as ulcerative colitis (UC) or Crohn’s disease (CD) is often regarded as the initial trigger for the development of CRC. Many cytokines such as tumor necrosis factor alpha (TNF-α) and several interleukins (ILs) are known to exert proinflammatory actions, and inflammation initiates or promotes tumorigenesis of various cancers, including CRC through differential regulation of microRNAs (miRNAs/miRs). miRNAs can be oncogenic miRNAs (oncomiRs) or anti-oncomiRs/tumor suppressor miRNAs, and they play key roles during colorectal carcinogenesis. However, the functions and molecular mechanisms of regulation of miRNAs involved in inflammation-associated CRC are still anecdotal and largely unknown. Consolidating the published results and offering perspective solutions to circumvent CRC, the current review is focused on the role of miRNAs and their regulation in the development of CRC. We have also discussed the model systems adapted by researchers to delineate the role of miRNAs in inflammation-associated CRC.

The Crisis of Social Institutions and Police Homicides: The Adverse Effects of Low Institutional Control

2021 ◽  
pp. 108876792110184
Author(s):  
Kamali’ilani T. E. Wetherell ◽  
Terance D. Miethe
Keyword(s):  
Public Policy ◽  
Adverse Effects ◽  
Census Data ◽  
Social Institutions ◽  
Crime Rates ◽  
Future Research ◽  
Homicide Rates ◽  
Institutional Control ◽  
Different Levels

Using U.S. census data and a multi-source database on officer-involved killings, the current study extends previous research by exploring the influence of measures of weak social control in economic, educational, and familial institutions on state rates of police homicide. States with lower levels of institutional control are found to have higher overall rates of police homicides and police killings involving Black, Hispanic, and White decedents. The significant effects of institutional control on these police homicide rates are generally found to exhibit contextual invariance across different levels of various control variables (e.g., comparisons of states with low or high violent crime rates, low vs high economic inequality, low vs high levels of urbanization). These results and the limitations of this study are discussed in terms of implications for future research and public policy on police homicides and the role of social institutions in minimizing the occurrence of these incidents.

scholarly journals Ayurvedic Management of Infertility W.S.R. Anovulation: A Case Study

2019 ◽  
Vol 9 (5-s) ◽  
pp. 151-153
Author(s):  
Neha Pandya ◽  
Hetal P. Baraiya
Keyword(s):  
Adverse Effects ◽  
Ovulatory Cycle ◽  
Menstrual Cycles ◽  
Married Life ◽  
Anovulatory Cycle ◽  
Present Case Study

Patient was anxious to conceive after active married life of 5 years. The present case study was done to evaluate the role of Ayurvedic Shodhana therapy i.e. Yogabasti for two consecutive menstrual cycles in the management of anovulation. After completing two courses of Yogabasti, improvement was noticed i.e. Ovulation study (during treatment - anovulatory cycle, After treatment - ovulatory cycle). The line of treatment was followed in this case was to treat the provoked Vata Dosha and vitiated Rasa Dhatu. There were no adverse effects found during the Ayurvedic Panchakarma procedure i.e. Yogabasti. Keywords: Anovulation, Panchakarma, Shodhana, Yogabasti

scholarly journals Acupuncture for Primary Dysmenorrhea: A Potential Mechanism from an Anti-Inflammatory Perspective

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Wen-Yan Yu ◽  
Liang-Xiao Ma ◽  
Zhou Zhang ◽  
Jie-Dan Mu ◽  
Tian-Yi Sun ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Animal Studies ◽  
Visceral Pain ◽  
Self Healing ◽  
Primary Dysmenorrhea ◽  
Potential Mechanism ◽  
Future Studies ◽  
Anti Inflammatory ◽  
Proinflammatory Factors

The low adverse effects of acupuncture for primary dysmenorrhea (PD), known as one of the most commonly reported gynecological debilitating conditions affecting women’s overall health, have been thus far confirmed. Moreover, it has been increasingly recognized that inflammation is involved in such menstrual cramps, and recent studies have further shown that the anti-inflammatory effects of acupuncture are helpful in its control. This review portrays the role of inflammation in PD pathophysiology, provides evidence from clinical and animal studies on acupuncture for inflammation-induced visceral pain, and reflects on acupuncture-related therapies for dysmenorrhea with regard to their anti-inflammatory characteristics. Further research accordingly needs to be carried out to clarify the effects of acupuncture on proinflammatory factors in PD, particularly chemokines and leukocytes. Future studies on this condition from an anti-inflammatory perspective should be also performed in line with the notion of emphasizing stimulation modes to optimize the clinical modalities of acupuncture. Additionally, the effects and mechanism of more convenient self-healing approaches such as TENS/TEAS for PD should be investigated.

scholarly journals Effect of Sulfur and Clean Salt on Antioxidant Enzymes and Proline Content in Improving Salt Tolerance of Two Lettuce Cultivars Grown in Basrah

2019 ◽  
Vol 32 ◽  
pp. 80-89
Author(s):  
Jameel H. Hiji ◽  
Abbas M. Jasim ◽  
Awatif N. Jerry
Keyword(s):  
Electrical Conductivity ◽  
Antioxidant Enzymes ◽  
Salt Tolerance ◽  
Adverse Effects ◽  
Irrigation Water ◽  
Sandy Loam ◽  
Proline Content ◽  
Salt Tolerant ◽  
Loam Soil

The experiment was conducted during 2017-2018 and 2018-2019 winter seasons at Abu Al-Khaseeb District at basrah /Iraq on sandy loam soil  to study the effect of sulfur at five concentration ( 0 , 500 , 1000, 1500 and 2000) kg. Ha-1, clean salt at three concentration (0, 0.5 and 1.0) ml. L-1, two cultivars of lettuce local and fajr and interaction among them  at electrical conductivity of the irrigation water (7.85 and 9.69) dS.m-1.  Result showed significant reduction in the activity of catalase (CAT) and peroxidase (POD) enzymes and proline content in all treatments of sulfur and clean salt especially at 2000 Kg. Ha-1 sulfur and clean salt at 1.0 ml L-1had significantly decrease in CAT activity (295.80 ? 341.65) U mg–1 FW, POD activity (7.86? 8.98) U mg–1 FW and proline (0.50 ? 0.80) mg g-1DW, comparing with control of CAT activity (663.21, 814.65) U mg–1 FW and POD activity (13.83, 15.52) mg–1 FW and proline (1.19, 2.03) mg g-1DW, respectively for two seasons due to the role of sulfur and clean salt ameliorates the adverse effects of salinity on plants. Fajr lettuce is more salt-tolerant than local due to less antioxidant enzyme levels POD, CAT and proline.

scholarly journals Analysis of the Role of Female Hormones During Infection by COVID-19

2021 ◽  
Vol 43 (12) ◽  
pp. 940-948
Author(s):  
David Balbino Pascoal ◽  
Isabela Macêdo de Araujo ◽  
Lorenna Peixoto Lopes ◽  
Cristiane Monteiro da Cruz
Keyword(s):  
Relative Risk ◽  
Adverse Effects ◽  
Data Sources ◽  
Hormonal Contraceptives ◽  
Review Of The Literature ◽  
Sexual Hormones ◽  
Auxiliary Data ◽  
The World ◽  
Coronavirus Infection

AbstractWomen have metabolic, immunological, and genetic variables that ensure more protection from coronavirus infection. However, the indication of treatment for several pathologies and contraception is determined by hormones that have adverse effects and raise doubts about their use during the COVID-19 pandemic. Therefore, the present study searches women specificities and the relation between female sexual hormones and COVID-19, and reports the main recommendations in this background. To this end, a review of the literature was conducted in the main databases, auxiliary data sources, and official websites. Therefore, considering the hypercoagulability status of COVID-19, the debate about the use of contraceptives due to the relative risk of thromboembolic effects that they impose arises. However, the current available evidence, as well as the recommendations of main health organs around the world, demonstrate that the use of hormonal contraceptives must be maintained during the pandemic.

scholarly journals Collective Goods, Free Riding and Country Brands: The Chinese Experience

2008 ◽  
Vol 4 (2) ◽  
pp. 211-223 ◽  
Author(s):  
Jay B. Barney ◽  
Shujun Zhang
Keyword(s):  
Intellectual Property ◽  
Adverse Effects ◽  
Free Riding ◽  
Average Quality ◽  
Collective Goods ◽  
Country Brand ◽  
The Government ◽  
The Stability

Company brands signify a message to consumers about the quality and value of a product. Countries can also be branded. However, unlike the brands of individual firms, country brands are collective goods. The nature of country brands creates the possibility of free riding, where individual firms benefit – in terms of price or access – from the promise made by a country brand but deliver at a level lower than what is promised by the brand. Such free riding threatens the stability of what the country brand represents unless legal, governmental, or other institutions engage in activities to reduce these adverse effects. In this paper, we investigate the Chinese brand – once standing for average quality at a low price – in the light of recent recalls. We examine how country brands emerge and the incentives that firms operating in a country have to either support or not support a country brand. We also explore the implications of diese incentives for the role of various institutions, including the government, in developing, maintaining and changing a country brand and in developing and enforcing the policies, such as protection of intellectual property, necessary to support firms' efforts toward reinforcing a trusted country brand.

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