Suicidal Ideation Amongst Adolescent Suffering from Disordered Eating: The Young-HUNT Study

2017 ◽  
Vol 41 (S1) ◽  
pp. S88-S89
Author(s):  
F. Saeedzadeh Sardahaee ◽  
T. Lingaas Holmen ◽  
N. Micali ◽  
K. Kvaløy

IntroductionSuicide takes a great toll on both individuals and societies. Successful preventive measures would require a careful understanding of the scope of suicidal ideation as well as its associated factors. Amongst mental disorders, anorexia nervosa has the highest mortality rate due to suicide.Objective and aimsStudying the prevalence of suicidal ideation and its associated factors in adolescents (13–19 years old) affected by disordered eating (DE).MethodsLogistic regression was employed to study associations between suicidal ideation and age, gender and disordered eating in adolescents from a population-based prospective study, The Young-HUNT 3 cohort, 2006-8. DE cases were defined using the self-reported questionnaire (Eating Attitude Test-7) and then grouped into two subscales, poor appetite/under-eating and uncontrolled appetite/overeating.ResultsA total of 3933(boys 49% and 51% girls) were included. In total, 177 poor appetite/under-eating and 365 uncontrolled appetite/overeating cases were identified. Prevalence of suicidal ideation was 24.5% in total sample with girls being more affected (27.1%). Prevalence of suicidal ideation amongst poor appetite/under-eating case group and uncontrolled appetite/overeating cases was respectively 43.5 and 39.2%. The odds-ratio of suicidal ideation amongst poor appetite/under-eating cases compared to control group was 2.56 (95% CI, 1.85 to 3.42, P-value < 0.001) whilst the odds-ratio of suicidal ideation amongst uncontrolled appetite/overeating cases compared to control group was 2.19 (95% CI, 1.75 to 2.74, P-value < 0.001). Results remained significant after adjusting for anxiety and depression symptoms.ConclusionFocus on high risk groups such as DE seems important in taking suicide preventive measures.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Neonatology ◽  
2020 ◽  
pp. 1-7
Author(s):  
Tobias Hengartner ◽  
Mark Adams ◽  
Riccardo E. Pfister ◽  
Diane Snyers ◽  
Jane McDougall ◽  
...  

<b><i>Aim:</i></b> The aim of this study is to examine possible associations between the transfusion of RBC or platelets (PLTs) and the development of retinopathy of prematurity (ROP) in infants. <b><i>Methods:</i></b> This retrospective, national, case-control study included all live births in Switzerland between 2013 and 2018. We investigated preterm infants at a gestational age of &#x3c;28 weeks, who developed higher stage ROP (≥stage 2, <i>n</i> = 178). Each case infant was matched to another of the same sex who did not develop ROP (<i>n</i> = 178, control group). <b><i>Results:</i></b> When compared with the control group, we observed higher numbers of RBC transfusions per infant and higher percentages of infants receiving PLT transfusions in the case group. An adjusted logistic regression analysis revealed that both RBC (odds ratio [OR] 1.081, 95% confidence interval [CI] 1.020–1.146) and PLT transfusions (OR = 2.502, 95% CI 1.566–3.998) numbers were associated with ROP development. <b><i>Conclusions:</i></b> Multiple RBC and PLT transfusions are associated with higher stage ROP development. Prospective studies are required to determine their potential as risk factors.


Author(s):  
Suchithra Erath Thadathil ◽  
Jaya Koothupalakkal Viswambharan ◽  
Alok Kanjhoor Premdas ◽  
Ashwin Raj

Background: Air pollution leads to several health effects, the major systems affected were respiratory, dermatology, neurology and ophthalmology. This study is an attempt to find out various health effects of pollution, from a food factory to the nearby residents.Methods: A cross sectional comparative study was performed on 248 residents nearby a food factory, situated in rural area of Thrissur district and a comparative group of 266 participants taken 5km away from this factory.Results: Both the groups were comparable in socio-demographic profile except religion and occupation. There was no statistically significant difference (p>0.05) between the use of firewood in both the groups. The symptoms of major systems involved were respiratory (odds ratio 3.9, 95% CI 2.2 to 6.8), dermatological (odds ratio 18.3, 95% CI 8.3 to 40.7), neurological (odds ratio 13.5, 95% CI 4.1 to 44.7) and ophthalmological (odds ratio 5.9, 95% CI 2.6 to 13.6). The major symptoms complained by them were pruritus (32.7%), skin lesions (17.7%), breathlessness (16.9%), itching eye (13.3%) watering from eye (11.7%) and headache (11.3%). All these symptoms among the case group compared to control group were very high and these associations were highly statistically significant (p<0.001).Conclusions: This study showed an increased occurrence of adverse health effects among the individuals who were residing near the food factory. Therefore this study points out the possibility of environmental pollution (mainly air pollution) as a main factor for the increased prevalence of symptoms among those who reside nearby the factory.


2021 ◽  
Vol 74 (7) ◽  
pp. 1617-1621
Author(s):  
Vadym P. Shypulin ◽  
Oleksandr A. Martynchuk ◽  
Nikolai N. Rudenko ◽  
Aleksandr K. Koliada ◽  
Viktoriia V. Tishchenko ◽  
...  

The aim: To study the association between the effectiveness of treatment with pioglitazone non-alcoholic fatty liver disease (NAFLD) in patients with obesity and PPARG rs1801282 (Pro12Ala)-polymorphism in Ukrainians. Materials and methods: 123 patients with NAFLD in combination with obesity 1, 2, 3 classes were included in comprehensive weight loss program (5 visits, 12-weeks). The case group was treated with pioglitazone 15 mg / day, while the control group received only program. Ultrasound (US) steatometry and genetic testing rs1801282 polymorphism in PPARG gene were performed. Results: Pioglitazone, PPARG rs1801282 genotype, CAP before treatment, previous weight loss attempts, and duration of obesity were associated with the change in controlled attenuation parameter (CAP) during treatment. There was a significant association between the target CAP reduction achievement and pioglitazone treatment (adjusted odds ratio 0.23, 95% CI 0.07–0.73; p = 0.01) with the CC genotype of PPARG gene (adjusted odds ratio 92.9, 95% CI 7.4–1159; p < 0.001) compared to patients with the CG genotype. Conclusions: Pioglitazone and PPARG rs1801282 polymorphism could influence on dynamics of CAP reduction during treatment.


2018 ◽  
Vol 18 (1) ◽  
pp. 208
Author(s):  
Listautin Listautin

Diarrhea is one of health problem in the world including Indonesia. The Morbidity survey undertaken by Sub-Directorate of diarrhea, Health Department from 2007 to 2010is improved. According to the data gained from Puskesmas in Tanjung Pinang Jambi in 2017, it is found out that 5 different districs in Tanjung Pinang are the district which has the highest rate of diarrhea sufferers. The aim of this study is to find out the risk factors of the flies density and the dwelling sanitation to the occurance of diarrhea in Tanjung Pinang Jambi in 2017. This study is quantitative study by using case control design. The sample of this study is 68 people who consists of 34 samples of case group and 34 samples of control group. This study is analyzed through univariate and bivariate analysis by using chi-square test. The instruments of this study are the reviewed document, ceklist, and the measurement through fly grill. The result of analysis are found out that toilet is the main risk factor for the occurance of diarrhea with odds ratio (OR) value is 3,519. Sewerage (SPAL) is one the risk factor of the diarrhea occurance with odds ratio (OR) value is 3,361. The waste is the other risk factors for the occurance of diarrhea with odds ratio (OR) value is 4,418. The flies density is the protective factor for the diarrhea occurance with odds ratio (OR) value is 0,773.Based on the result of this study, it can be concluded that it is necesarry to do the coorporation across program to optimize the noticing of information to public concerning on the importance of good dwelling sanitation and the low flies density in order to avoid from the occurance of diarrhea.Keyword : Diarrhea, Dwelling Sanitation, Flies Density


2016 ◽  
Vol 15 (1) ◽  
pp. 44-47 ◽  
Author(s):  
Jorge Álvaro González Ross ◽  
Alfredo Javier Moheno Gallardo ◽  
Eulalio Elizalde Martínez ◽  
José Manuel Pérez Atanasio ◽  
Ruth Martínez Martínez

ABSTRACT Objective: To identify whether the use of prophylactic intrasite vancomycin as an adjuvant is a protective factor against deep tissue infection of the surgical site. Methods: Retrospective, descriptive, case-control study evaluating 210 patients, of whom 70 received intrasite vancomycin (case group) and 140 were controls. It was made a follow up for at least one year, reviewing the physical and electronic records. Data were tabulated in spreadsheets (Excel) including all variables and the statistical analysis was made with Epi InfoTM 7 to calculate the odds ratio. Results: Seven cases of deep infection occurred in the control group and none was found in the case group (odds ratio [95% confidence interval]: 0.1262 [0.007-2.24], P = 0.1585). Among the predisposing factors, diabetes and surgical time were the most relevant. Conclusions: Intrasite use of vancomycin has a protective effect against deep infection in patients undergoing lumbar fusion surgery without presenting considerable side effects.


2019 ◽  
Vol 32 (5-6) ◽  
pp. 125-34
Author(s):  
Iskandar Z. Lubis

From March thru April 1990 an unmatched case-control study had been conducted at the pediatric out-patient Clinic of Dr. Pirngadi Hospital Medan to assess risk factors of infantile diarrhea. The  study population were infants, aged younger than 21 months. The mothers of the infants were interviewed, using structured questionnaires. Sample size, calculated by means of formula, with 95 % level of confidence, 90 % power of study, 50% estimated proportion of exposure in the control-group and 2.0 estimated odds ratio, was 121. All infants with diarrhea were included in the case-group until a total number of 124 infants were reached. One control, an infant without diarrhea, was taken for each case from the nearest sequence of attendance after the case. A total of 20 risk factors were tested. Exposure was indicated from the last day before illness. Computerized statistical analysis was performed to calculate odds ratio, 95 % confidence interval and two tailed significance testing for qualitative dichotomic data by means of Chi square test. A total of nine factors were confirmed as risk factors of infantile diarrhea i.e mothers age than 20 years, working mother, not cleaning nipple before suckling the baby bottle feeding, having only one nursing botlle/teat, not ready for use nursing bottle/teat, giving left over supplementary food without reheating, no band-washing before giving supplementary food and malnutrition. The result of this study can be emphasized in health education, especially in diarrheal disease control of infancy; Further well-designed studies are needed.


2019 ◽  
Author(s):  
Mark B Schure ◽  
Janet C Lindow ◽  
John H Greist ◽  
Paul A Nakonezny ◽  
Sandra J Bailey ◽  
...  

BACKGROUND Although internet-based cognitive behavior therapy (iCBT) interventions can reduce depression symptoms, large differences in their effectiveness exist. OBJECTIVE The aim of this study was to evaluate the effectiveness of an iCBT intervention called Thrive, which was designed to enhance engagement when delivered as a fully automated, stand-alone intervention to a rural community population of adults with depression symptoms. METHODS Using no diagnostic or treatment exclusions, 343 adults with depression symptoms were recruited from communities using an open-access website and randomized 1:1 to the Thrive intervention group or the control group. Using self-reports, participants were evaluated at baseline and 4 and 8 weeks for the primary outcome of depression symptom severity and secondary outcome measures of anxiety symptoms, work and social adjustment, psychological resilience, and suicidal ideation. RESULTS Over the 8-week follow-up period, the intervention group (n=181) had significantly lower depression symptom severity than the control group (n=162; <italic>P</italic>&lt;.001), with a moderate treatment effect size (<italic>d</italic>=0.63). Moderate to near-moderate effect sizes favoring the intervention group were observed for anxiety symptoms (<italic>P</italic>&lt;.001; <italic>d</italic>=0.47), work/social functioning (<italic>P</italic>&lt;.001; <italic>d</italic>=0.39), and resilience (<italic>P</italic>&lt;.001; <italic>d</italic>=0.55). Although not significant, the intervention group was 45% less likely than the control group to experience increased suicidal ideation (odds ratio 0.55). CONCLUSIONS These findings suggest that the Thrive intervention was effective in reducing depression and anxiety symptom severity and improving functioning and resilience among a mostly rural community population of US adults. The effect sizes associated with Thrive were generally larger than those of other iCBT interventions delivered as a fully automated, stand-alone intervention. CLINICALTRIAL ClinicalTrials.gov NCT03244878; https://clinicaltrials.gov/ct2/show/NCT03244878


2018 ◽  
Vol 24 (3) ◽  
pp. 79 ◽  
Author(s):  
Dina Delvin Anggriani ◽  
Lilik Herawati ◽  
Ernawati Ernawati

Objectives: to identify factors affecting labor induction failure in Sungailiat General Hospital, District Bangka, Bangka Belitung.Materials and Methods: This is a case control retrospective analytic study. Population of this study was postterm delivering mother at delivery room Sungailiat General Hospital during July 1st, 2012 to July 1st, 2015. Sampling method conducted for case group was total sampling method with labor induction failure as a inclusion criteria, and no data for first trimester ultrasound, didn’t have a routine antenatal care history, and maternal complication as exclusion criterias as many as 78 samples. Whereas, control group was women whose underwent a success labor induction used random sampling method with 1:1 ratio. Data source was from medical records. Data analysis was chi square with 95% confidence interval.Results: From the 78 samples with labor induction, 19,2 % was ≥ 35 years old, 48,7% was primiparas, 62,8% with infant birth weight ≥ 3500 gram, and from 96 samples, 47,5% with ≥ 5 years pregnancy interval. Statistical analysis result showed factors that affecting induction failure were parity (P Value 0,014, odds ratio 2,970), baby’s weight (P Value 0,016, odds ratio 2,631), pregnancy interval (P Value 0,023, odds ratio 2,993), whereas mother’s age did not show significant effect (P Value 0,383, odds ratio 2,278).Conclusion: Parity has a 2,9 times risk to develop induction failure.


10.2196/14754 ◽  
2019 ◽  
Vol 21 (11) ◽  
pp. e14754 ◽  
Author(s):  
Mark B Schure ◽  
Janet C Lindow ◽  
John H Greist ◽  
Paul A Nakonezny ◽  
Sandra J Bailey ◽  
...  

Background Although internet-based cognitive behavior therapy (iCBT) interventions can reduce depression symptoms, large differences in their effectiveness exist. Objective The aim of this study was to evaluate the effectiveness of an iCBT intervention called Thrive, which was designed to enhance engagement when delivered as a fully automated, stand-alone intervention to a rural community population of adults with depression symptoms. Methods Using no diagnostic or treatment exclusions, 343 adults with depression symptoms were recruited from communities using an open-access website and randomized 1:1 to the Thrive intervention group or the control group. Using self-reports, participants were evaluated at baseline and 4 and 8 weeks for the primary outcome of depression symptom severity and secondary outcome measures of anxiety symptoms, work and social adjustment, psychological resilience, and suicidal ideation. Results Over the 8-week follow-up period, the intervention group (n=181) had significantly lower depression symptom severity than the control group (n=162; P<.001), with a moderate treatment effect size (d=0.63). Moderate to near-moderate effect sizes favoring the intervention group were observed for anxiety symptoms (P<.001; d=0.47), work/social functioning (P<.001; d=0.39), and resilience (P<.001; d=0.55). Although not significant, the intervention group was 45% less likely than the control group to experience increased suicidal ideation (odds ratio 0.55). Conclusions These findings suggest that the Thrive intervention was effective in reducing depression and anxiety symptom severity and improving functioning and resilience among a mostly rural community population of US adults. The effect sizes associated with Thrive were generally larger than those of other iCBT interventions delivered as a fully automated, stand-alone intervention. Trial Registration ClinicalTrials.gov NCT03244878; https://clinicaltrials.gov/ct2/show/NCT03244878


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