A New Device for Autologous Small Volume Fat Grafting

2020 ◽  
Author(s):  
Xiaonan Yang ◽  
Jonathan P Brower ◽  
Lauren Kokai ◽  
Beth R Gusenoff ◽  
Jeffrey A Gusenoff
Keyword(s):  
Small Volume ◽  
Cost Effective ◽  
Fat Grafting ◽  
Tissue Quality ◽  
Processing Efficiency ◽  
Handheld Technology ◽  
New Device ◽  
Handheld Device ◽  
And Function ◽  
Fat Processing

Abstract Background Many techniques and devices have been developed to improve small volume fat grafting efficiency and consistency for use in the operating room and outpatient procedure room. These methods require cumbersome or messy processing to remove excess oil and fluid from adipose graft. Objectives The aim of this study was to compare fat processing efficiency of a novel hand-held device, the Push-to-Spin (P2S™) system, to other common processing techniques and validate tissue quality after lipoaspirate processing. Methods Human lipoaspirate samples were processed using one of three experimental methods, including cotton gauze (Telfa) rolling, centrifugation (Coleman technique), or using the P2S™ system. Efficiency of fat processing was evaluated by total processing time, fat harvest ratio, and fat processed ratio. Histological examination and immunohistochemical staining were used to compare tissue morphology and adipocyte viability, respectively. Experimental samples were compared to unprocessed lipoaspirate controls. Results Lipoaspirate processing was significantly faster using the P2S™ device compared with other techniques. All three methods achieved similar fat harvest and fat processing ratios. Additionally, the P2S™, Telfa, and Coleman techniques yielded grafts with similar cellularity, and perilipin and GPDH expression. Measured differences between experimental and control samples were statistically significant. Conclusions The P2S™ device is an easy, efficient, and potentially cost-effective handheld device that can be used for lipoaspirate harvest, processing, and grafting in any procedural setting. The resulting adipocytes have similar morphology, viability, and function to those yielded by techniques. This handheld technology decreases procedure time, thereby improving surgeon efficiency and patient experience.

Review on Applications of Nanoparticles in Landfill Leachate Treatment

2015 ◽  
Vol 802 ◽  
pp. 525-530 ◽  
Author(s):  
Ghani Zaidi Ab ◽  
Mohd Suffian Yusoff ◽  
Jeyashelly Andas
Keyword(s):  
Photocatalytic Oxidation ◽  
Cost Effective ◽  
Environmental Benefits ◽  
Sanitary Landfill ◽  
Health Issues ◽  
Leachate Treatment ◽  
Processing Efficiency ◽  
Potential Applications ◽  
And Function ◽  
Dissolved And Suspended Matter

Sanitary landfill is the most common way to eliminate solid waste. However, sanitary landfill generates large quantity of leachate. Leachate can be defined as a liquid that passes through a landfill and extracted dissolved and suspended matter. The presence of large quantity of contaminants in leachate is harmful to human and ecological environment. This can lead to health issues, including gastrointestinal illness, reproductive problems, and neurological disorders. There are several significant techniques have been made to overcome the problem of leachate pollution, including photocatalytic oxidation, adsorption/separation processing and bioremediation. However, the applications have been restricted by many factors, such as processing efficiency, operational method, energy requirements, and economic benefit. This present article provides an overview of research studies and advances concerned with the development of nanoparticles and their potential applications in leachate treatment. Nanoparticles can act as antimicrobial and function as reducing agent and catalyst in detoxification of pollutants in the environment, such as organic, inorganic and heavy metals. NPs have been suggested as efficient, cost-effective and environmental friendly alternative to existing treatment materials and presents a number of potential environmental benefits.

Application of Fast Laser Deprocessing Techniques in Physical Failure Analysis on SRAM Memory of Advance Technology

2014 ◽  
Author(s):  
H.H. Yap ◽  
P.K. Tan ◽  
G.R. Low ◽  
M.K. Dawood ◽  
H. Feng ◽  
...  
Keyword(s):  
Failure Analysis ◽  
Integrated Circuit ◽  
Cost Effective ◽  
Tetraethyl Orthosilicate ◽  
Ic Design ◽  
Advance Technology ◽  
Defect Identification ◽  
Technology Scaling ◽  
And Function ◽  
Metal Layers

Abstract With technology scaling of semiconductor devices and further growth of the integrated circuit (IC) design and function complexity, it is necessary to increase the number of transistors in IC’s chip, layer stacks, and process steps. The last few metal layers of Back End Of Line (BEOL) are usually very thick metal lines (>4μm thickness) and protected with hard Silicon Dioxide (SiO2) material that is formed from (TetraEthyl OrthoSilicate) TEOS as Inter-Metal Dielectric (IMD). In order to perform physical failure analysis (PFA) on the logic or memory, the top thick metal layers must be removed. It is time-consuming to deprocess those thick metal and IMD layers using conventional PFA workflows. In this paper, the Fast Laser Deprocessing Technique (FLDT) is proposed to remove the BEOL thick and stubborn metal layers for memory PFA. The proposed FLDT is a cost-effective and quick way to deprocess a sample for defect identification in PFA.

scholarly journals 2D-3D integration of hexagonal boron nitride and a high-κ dielectric for ultrafast graphene-based electro-absorption modulators

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Hitesh Agarwal ◽  
Bernat Terrés ◽  
Lorenzo Orsini ◽  
Alberto Montanaro ◽  
Vito Sorianello ◽  
...  
Keyword(s):  
Boron Nitride ◽  
Hafnium Oxide ◽  
High Speed ◽  
Hexagonal Boron Nitride ◽  
Temperature Stability ◽  
Cost Effective ◽  
Fold Increase ◽  
Building Blocks ◽  
High Quality ◽  
New Device

AbstractElectro-absorption (EA) waveguide-coupled modulators are essential building blocks for on-chip optical communications. Compared to state-of-the-art silicon (Si) devices, graphene-based EA modulators promise smaller footprints, larger temperature stability, cost-effective integration and high speeds. However, combining high speed and large modulation efficiencies in a single graphene-based device has remained elusive so far. In this work, we overcome this fundamental trade-off by demonstrating the 2D-3D dielectric integration in a high-quality encapsulated graphene device. We integrated hafnium oxide (HfO2) and two-dimensional hexagonal boron nitride (hBN) within the insulating section of a double-layer (DL) graphene EA modulator. This combination of materials allows for a high-quality modulator device with high performances: a ~39 GHz bandwidth (BW) with a three-fold increase in modulation efficiency compared to previously reported high-speed modulators. This 2D-3D dielectric integration paves the way to a plethora of electronic and opto-electronic devices with enhanced performance and stability, while expanding the freedom for new device designs.

scholarly journals PSVII-3 Correlations between L-lactate concentrations obtained using a handheld lactate analyser and a lactate assay colorimetric kit in beef cattle transported by road

2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 296-297
Author(s):  
Daniela M Meléndez ◽  
Sonia Marti ◽  
Luigi Faucitano ◽  
Derek B Haley ◽  
Timothy D Schwinghamer ◽  
...  
Keyword(s):  
Statistical Significance ◽  
Cost Effective ◽  
Road Transportation ◽  
Long Distance ◽  
Suitable Alternative ◽  
Blood Samples ◽  
Handheld Device ◽  
Time Points ◽  
Relationship Of ◽  
The Relationship

Abstract Blood metabolites are used to assess a variety of animal conditions for veterinary diagnosis and research. Concentration of metabolites in blood can be measured using a commercially-available lab-based assay or in real-time using a handheld device developed to be more time- and cost-effective than the lab-based method. Lactate is a product of anaerobic glycolysis, used in animal research as an indicator of muscle fatigue. Therefore, it has been used as an indicator of cattle response to long distance transportation. The aim of this study was to assess the relationship of L-lactate concentrations measured using a Lactate Scout+ analyzer (Lactate Scout, EFK Diagnostics, Barleben, Germany) and a lactate assay colorimetric kit (Lactate Assay Kit, Cell Biolabs Inc., San Diego, CA). Blood samples were collected by venipuncture from 96 steers (245 ± 35.7 kg BW) prior to (L1) and after 36 h, and prior to and after an additional 4 h of road transportation, and on d 1, 2, 3, 5, 14, and 28 after transport. The Lactate Scout+ analyzer strip was dipped in blood at the time of sampling, while blood samples were collected into sodium fluoride tubes for use in colorimetric analysis. Pearson correlations were calculated to determine the relationship between the experimental methods for the quantification of L-lactate concentrations. The strengths and levels of statistical significance of the correlation varied over the observed time points, r = -0.03, P = 0.75 (L1) to r = 0.75, P = < 0.0001 (d 3). The correlation for the pooled data was weak but statistically significant (r = 0.33, P < 0.001). Based on the experimental results, the Lactate Scout+ analyzer is not a suitable alternative to a lab-based assay for measuring L-lactate in transported cattle, due to variability across sampling time points and weak correlation with the traditional enzymatic method.

scholarly journals Marine Fish Primary Hepatocyte Isolation and Culture: New Insights to Enzymatic Dissociation Pancreatin Digestion

2021 ◽  
Vol 18 (4) ◽  
pp. 1380
Author(s):  
Neusa Figueiredo ◽  
Beatriz Matos ◽  
Mário Diniz ◽  
Vasco Branco ◽  
Marta Martins
Keyword(s):  
Cell Viability ◽  
Cell Cultures ◽  
Marine Fish ◽  
Sparus Aurata ◽  
Cost Effective ◽  
Primary Hepatocyte ◽  
Digestion Method ◽  
Trypan Blue Exclusion ◽  
And Function

Primary cell cultures from wild organisms have been gaining relevance in ecotoxicology as they are considered more sensitive than immortalized cell lines and retain the biochemical pathways found in vivo. In this study, the efficacy of two methods for primary hepatocyte cell isolation was compared using liver from two marine fish (Sparus aurata and Psetta maxima): (i) two-step collagenase perfusion and (ii) pancreatin digestion with modifications. Cell cultures were incubated in L-15 medium at 17 ± 1 °C and monitored for up to six days for cell viability and function using the trypan blue exclusion test, MTT test, lactate dehydrogenase (LDH) activity, and ethoxyresorufin O-deethylase (EROD) activity after Benzo[a]Pyrene exposure. The results showed significant differences between the number of viable cells (p < 0.05), the highest number being obtained for the pancreatin digestion method (average = 4.5 ± 1.9 × 107 cells). Moreover, the hepatocytes showed solid adherence to the culture plate and the rounded shape, changing into a triangular/polygonal shape. The cell viability and function obtained by pancreatin digestion were maintained for five days, and the EROD induction after exposure to the B[a]P showed that cells were metabolically active. This study shows that the optimized pancreatin digestion method is a valid, cost-effective, and simple alternative to the standard perfusion method for the isolation of primary hepatocytes from fish and is suitable for ecotoxicological studies involving marine pollutants, such as PAHs.

scholarly journals Detachable Lip and Cheek Plumper for Rehabilitation of Facial Disfigurement

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Nada Fathalla Abdelbagi ◽  
Ibrahim Ahmed Ismail ◽  
Fadia Awadalkreem ◽  
Mohammed Nasser Alhajj
Keyword(s):  
Social Life ◽  
Alveolar Bone ◽  
Treatment Plan ◽  
Young Male ◽  
Cost Effective ◽  
Surgical Removal ◽  
Individual Character ◽  
Swallowing Difficulties ◽  
Oroantral Communication ◽  
And Function

Background. Hemimaxillectomy of acquired palatal defects may predispose the patient to hypernasal speech, leakage of fluids into the nasal cavity, impaired masticatory function, and swallowing difficulties leading to a detrimental impact on the quality of life. Sequentially, it can also affect individual character and trust in social life, leading to social phobia and anxiety. This article presents prosthodontic management of a young male patient with deformation of the entire right half of the face due to surgical removal of odontogenic myxoma. It describes a method where the clinician utilized a simple, noninvasive, and cost-effective technique to cut the weight of the obturator and to attain aesthetics, utilizing a detachable lip and cheek plumper. Case Presentation. A 19-year-old male attended the Prosthodontic Clinics at Faculty of Dentistry, the University of Khartoum, eight months after the surgical removal of a tumor. The chief complaint was difficulty eating or drinking. Furthermore, he dropped out of school because of his facial deformity and his indistinct voice. Medical and dental history revealed surgical resection of the entire right half of the maxillary alveolar bone due to myxoma. Intraoral examination revealed a well-healed surgical defect in the maxillary right buccal vestibule creating an oroantral communication. A treatment plan was formulated, keeping the patient’s demand in mind. The decision was made to treat the patient with a maxillary obturator that would gain its support from the remaining teeth and tissues with a detachable cheek and lip plumper. The use of dental magnets as a means of attachment was elected. Conclusion. This article has described a simple, noninvasive, and cost-effective method to improve facial appearance in patients with hollow faces. The plumper prosthesis successfully improved the patient’s appearance to the extent that comfort and function would permit and encourage self-esteem.

Recent Patents on Bearing Pre-tightening

2021 ◽  
Vol 15 ◽  
Author(s):  
Yanling Zhao ◽  
Jiashuo Zhang
Keyword(s):  
Research Direction ◽  
Development Trend ◽  
Machining Accuracy ◽  
Processing Efficiency ◽  
Tightening Force ◽  
The Future ◽  
Processing Accuracy ◽  
And Function ◽  
The Development Trend ◽  
Accuracy Speed

Background: Bearing has been widely used in automotive, aerospace, electronics industry, and other fields.Its pre-tightening technology is one of the most critical technologies. It has an important influence on the accuracy, speed, stiffness, and temperature rise of the spindle. Proper pre-tightening force can eliminate bearing clearance and improve machining accuracy and efficiency of machine tools. Therefore, the development trend of bearing pre-tightening mechanism has been paid more and more attention. Objective: In order to improve the processing efficiency and processing accuracy of the bearing system, the structure and function of the bearing pre-tensioning device are continuously enhanced. Methods: This paper retraces various current representative patents relative to the mechanism of bearing pre-tightening. Results: Through the investigation of several patents of bearing pre-tightening devices, the principles and effects of different bearing pre-tightening devices are classified and reviewed. Besides, the future development trend of bearing pre-tightening devices is discussed. Conclusion: The optimization of the bearing pre-tightening device is conducive to improving processing efficiency and quality. A controllable pre-tightening force is the research direction, and more related patents will be invented in the future.

Technology Insertion in the U.S. Navy

2006 ◽  
Author(s):  
Martin Quin˜ones ◽  
Kevin Fauvell
Keyword(s):  
Cost Effective ◽  
Leadership Role ◽  
Acquisition Reform ◽  
New Perspective ◽  
And Function ◽  
The U.S

With a new perspective on how to conduct business through acquisition reform, the Navy faces infrastructure challenges that are not necessarily in sync with acquisition principles. Historically, the U.S. Navy (Navy hereinafter) has always spearheaded the means of developing design for form, fit, and function of Navy machinery. This leadership role has its roots on the unique requirements that the U.S. Navy has to fulfill its mission. Unfortunately, this process does not always prove to be cost effective since its implementation normally carries heavy restrictions, unique applications, and little competition. This is commonplace for most technology insertion efforts into Navy Ships.

Lipofilling to the Buttocks and Breasts in Local Anesthesia Using VASER and Expansion Vibration Lipofilling in a Closed-Loop System

2020 ◽  
pp. 074880682095649
Author(s):  
Roland Boeni ◽  
Paul von Waechter-Gniadek
Keyword(s):  
Local Anesthesia ◽  
Large Volume ◽  
Closed Loop ◽  
Operation Time ◽  
Cost Effective ◽  
Fat Grafting ◽  
Loop System ◽  
Closed Loop System ◽  
Satisfaction Rate ◽  
Fat Extraction

Large-volume fat transfer to the buttocks and breast has rapidly become popular. Lipofilling using syringes is tedious, time-consuming, and carries the risk of contamination. Most often, systemic anesthesia is being used. This study aims to evaluate the efficacy of large-volume lipofilling in local anesthesia. Local anesthesia was performed with 2 anesthetics: lidocaine and prilocaine. We performed vibration amplification of sound energy at resonance (VASER) and reciprocating power-assisted liposuction (PAL) for fat collection in a closed-loop system using a peristaltic pump. In a reverse pump setting, fat was then used for expansion vibration lipofilling. Pre- and postoperative data were collected. There were no major complications. Liposuction volumes up to 3.100 mL were extracted, and injection volumes ranged from 200 to 1600 mL. Mean operation time was 96 minutes. Satisfaction rate was high. Anesthesia was sufficient in all patients. Using a closed-loop system for fat extraction–purification and transfer is not only time- and cost-effective but also ideal for large-volume fat grafting. Recovery time is 1 to 2 days and satisfaction rate is high.

Geobiology of In Situ Uranium Leaching

2013 ◽  
Vol 825 ◽  
pp. 372-375 ◽  
Author(s):  
Carla Zammit ◽  
Kan Li ◽  
Barbara Etschmann ◽  
Joël Brugger ◽  
Frank Reith
Keyword(s):  
Microbial Communities ◽  
Underground Mining ◽  
Close Association ◽  
Cost Effective ◽  
Open Pit ◽  
Uranium Recovery ◽  
Production Studies ◽  
Site Rehabilitation ◽  
And Function

Driven by the world’s thirst for energy, the demand for uranium is rapidly increasing. Hence, producers of uranium are struggling to keep up with demands and are exploring more cost-effective methods of extraction. Uranium is currently mined via open pit and underground mining as well as with in situ leaching methods, with in situ leaching currently accounting for approximately 45 % of total uranium production. Studies have shown that the presence of uranium in soils strongly affects the composition and function of resident microbial communities. In view of the close association of biological processes and uranium geochemistry, it is surprising how little information is available on the effect of microbial communities on in situ leaching. Hence, this review focuses on the possibility to exploit the properties of such microorganisms and identify opportunities to use natural microbial processes to improve uranium recovery and mine site rehabilitation.

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