The Impact of Adolescent Obesity on Adult Height

2017 ◽  
Vol 88 (3-4) ◽  
pp. 237-243 ◽  
Author(s):  
Avivit Brener ◽  
Rachel Bello ◽  
Yael Lebenthal ◽  
Michal Yackobovitch-Gavan ◽  
Moshe Phillip ◽  
...  
Keyword(s):  
Adult Height ◽  
Normal Weight ◽  
Health Concern ◽  
Morbidly Obese ◽  
Pediatric Endocrinology ◽  
Major Health ◽  
Excess Adiposity ◽  
Parental Height ◽  
The Difference ◽  
The Impact

Background: Childhood obesity is a major health concern. Excess adiposity during childhood affects growth and puberty. Our aim was to assess whether genetic adult height is compromised in adolescents with obesity. Methods: In a retrospective study of 190 obese patients followed at our Pediatric Endocrinology Institute, adult height and delta height (the difference between adult height and mid-parental height) were compared to those of 150 healthy age-matched normal-weight controls. Review of medical files yielded the relevant clinical and anthropometric data of patients, controls, and parents. Results: Of the 190 obese adolescents, 150 were morbidly obese. The median adult height of morbidly obese males was 174.3 cm, of obese males 174 cm, and of normal-weight males 176 cm (p = 0.025). Delta height of morbidly obese males was –0.5 cm, of obese males –0.8 cm, and of normal-weight males, 3 cm (p < 0.0001). The median adult height of morbidly obese females was 161.3 cm, of obese females 162.8 cm, and of normal-weight females 162 cm (p = 0.37). Delta height of morbidly obese females was –1.85 cm, of obese females –0.95 cm, and of normal-weight females 0.7 cm (p = 0.019). Impairment of potential genetic height was not associated with obesity-related comorbidities. Conclusion: Adolescents with obesity showed impairment of potential genetic adult height as compared to that of normal-weight subjects.

Healthy Lifestyle Behaviors Among 18- to 49-Year-Old Women: A Comparative Study

2020 ◽  
pp. 0272684X2097383
Author(s):  
Seda Göger ◽  
Dilek Cingil
Keyword(s):  
Healthy Lifestyle ◽  
Normal Weight ◽  
Health Concern ◽  
Counseling Services ◽  
Lifestyle Behaviors ◽  
Obese Women ◽  
Significant Difference ◽  
Healthy Lifestyle Behaviors ◽  
Prevalence Of Obesity ◽  
The Difference

Introduction The prevalence of obesity has become a remarkable public health concern in a global extent. This study aimed to examine the difference between the healthy lifestyle behaviors of women with normal weight and those who are obese. Method This comparative descriptive study included a total of 302 women aged 18–49 years. Results According to regression analysis; duration of education (β = −0.154), (age (β = 0.376), presence of obese individuals in the family (β = 0.177) and HLSBS II scores (β = −0.115) were the factors that affected the BMI. The predictive value of these variables was 34.1%. Discussion A significant difference was found between women with normal weight and obese women in terms of several sub-dimensions and overall HLSBS II score. We recommend that healthcare staff should design training and counseling services to improve the health behaviors of overweight and obese women.

Appendicitis, Body Mass Index, and CT: Is CT More Valuable for Obese Patients than Thin Patients?

2011 ◽  
Vol 77 (4) ◽  
pp. 471-475 ◽  
Author(s):  
Courtney A. Coursey ◽  
Rendon C. Nelson ◽  
Ricardo D. Moreno ◽  
Mayur B. Patel ◽  
Craig A. Beam ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Normal Weight ◽  
Morbidly Obese ◽  
Negative Appendectomy ◽  
Obese Patients ◽  
Procedure Code ◽  
Preoperative Ct ◽  
The Difference ◽  
Underweight Patients

The purpose of our study is to determine whether body mass index (BMI = weight in kg/height in meters2) was related to the rate of negative appendectomy in patients who underwent preoperative CT. A surgical database search performed using the procedure code for appendectomy identified 925 patients at least 18 years of age who underwent urgent appendectomy between January 1998 and September 2007. BMI was computed for the 703 of these 925 patients for whom height and weight information was available. Patients were stratified based on body mass index (BMI 15-18.49 = underweight; 18.5-24.9 = normal weight; 25–29.9 = overweight; 30-39.9 = obese; > 40 = morbidly obese). Negative appendectomy rates were computed. Negative appendectomy rates for patients who did and did not undergo preoperative CT were 27 per cent and 50 per cent for underweight patients, 10 per cent and 15 per cent for normal weight patients, 12 per cent and 17 per cent for overweight patients, 7 per cent and 30 per cent for obese patients, and 10 per cent and 100 per cent for morbidly obese patients. The difference in negative appendectomy rates for overweight patients, obese patients, and morbidly obese patients who underwent preoperative CT as compared with patients in the same BMI category who did not undergo preoperative CT was statistically significant ( P ≤ 0.001). The negative appendectomy rates for overweight patients, obese patients, and morbidly obese patients who underwent preoperative CT were significantly lower than for patients in these same BMI categories who did not undergo preoperative CT.

scholarly journals Perioperative Outcomes among Patients with the Modified Metabolic Syndrome Who Are Undergoing Noncardiac Surgery

2010 ◽  
Vol 113 (4) ◽  
pp. 859-872 ◽  
Author(s):  
Laurent G. Glance ◽  
Richard Wissler ◽  
Dana B. Mukamel ◽  
Yue Li ◽  
Carol Ann B. Diachun ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Noncardiac Surgery ◽  
Normal Weight ◽  
Perioperative Outcomes ◽  
Morbidly Obese ◽  
Improvement Program ◽  
Super Obese ◽  
Risk Of Death ◽  
Increased Risk ◽  
The Impact

Background Previous studies have demonstrated that obesity is paradoxically associated with a lower risk of mortality after noncardiac surgery. This study will determine the impact of the modified metabolic syndrome (defined as the presence of obesity, hypertension, and diabetes) on perioperative outcomes. Methods This study is based on data from 310,208 patients in the American College of Surgeons National Surgical Quality Improvement Program database. We estimated separate multivariate logistic regression models for 30-day mortality and for 30-day complications. Results Patients with the modified metabolic syndrome who are super obese had a 2-fold increased risk of death (adjusted odds ratio [AOR] 1.99; 95% CI 1.41-2.80). As stratified by body mass index, patients with the modified metabolic syndrome had a 2- to 2.5-fold higher risk of cardiac adverse events (CAE) compared with normal-weight patients: obese (AOR 1.70; 95% CI 1.40-2.07), morbidly obese (AOR 2.01; 95% CI 1.48-2.73), and super obese (AOR 2.66; 95% CI 1.68-4.19). In addition, the risk of acute kidney injury (AKI) was 3- to 7-fold higher in these patients: obese (AOR 3.30; 95% CI 2.75-3.94), morbidly obese (AOR 5.01; 95% CI 3.87-6.49), and super obese (AOR 7.29; 95% CI 5.27-10.1). Conclusion Patients with the modified metabolic syndrome undergoing noncardiac surgery are at substantially higher risk of complications compared with patients of normal weight.

scholarly journals Short- and medium-term impact of bariatric surgery on the activities of CYP2D6, CYP3A4, CYP2C9, and CYP1A2 in morbid obesity

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Jose Rodríguez-Morató ◽  
Albert Goday ◽  
Klaus Langohr ◽  
Mitona Pujadas ◽  
Ester Civit ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Body Mass Index ◽  
Morbid Obesity ◽  
Body Mass ◽  
Surgical Techniques ◽  
Normal Weight ◽  
Morbidly Obese ◽  
Cyp3a4 Activity ◽  
Medium Term ◽  
The Impact

AbstractMorbid obesity and bariatric surgery induce anatomical, physiological and metabolic alterations that may alter the body’s disposition of drugs. Current literature on this topic is limited and sometimes inconsistent. Cytochrome P450 (CYP) is a superfamily of enzymes that metabolize around 75% of all marketed drugs. The purpose of this study was to evaluate the impact of body mass index and bariatric surgery on CYP activities. Firstly, we evaluated the in vivo activity of 4 major CYP isoenzymes (CYP2D6, CYP3A4, CYP2C9, and CYP1A2) in normal weight, overweight, and morbidly obese individuals. Secondly, we assessed the short- (1 month) and medium-term (6 month) effects of the most commonly employed bariatric surgery techniques (laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass) on the activity of these enzymes. CYP3A4 activity was lower in morbidly obese individuals, compared to normal-weight controls. Interestingly, bariatric surgery normalized CYP3A4 activity. In comparison with normal-weight controls, morbidly obese individuals had higher CYP2D6 activity, which was only observed in individuals with two functional alleles for this isoenzyme. Neither body mass index nor surgery had significant effects on CYP2C9 and CYP1A2 activities. Overall, no relevant differences in CYP activities were found between surgical techniques. In conclusion, further studies should evaluate whether the observed alterations in CYP3A4 activity will require dose adjustments for CYP3A4 substrates especially in morbidly obese individuals before and after bariatric surgery.

The Role of Underweight in Active Life Expectancy Among Older Adults in Japan

2020 ◽  
Author(s):  
Yuka Minagawa ◽  
Yasuhiko Saito
Keyword(s):  
Older Adults ◽  
Life Expectancy ◽  
Poor Quality ◽  
Normal Weight ◽  
The Body ◽  
Health Concern ◽  
Smoking History ◽  
Active Life Expectancy ◽  
Active Life ◽  
The Impact

Abstract Objectives It is underweight, rather than overweight or obesity, that has been a pressing public health concern in Japan. This study examines the impact of being underweight on the health of older Japanese men and women, measured by active life expectancy at age 65. Following the Japanese government’s guideline, underweight in this study is defined using the body mass index (BMI) value of 20. Method Data came from five waves (1999–2009) of the Nihon University Japanese Longitudinal Study of Aging (NUJLSOA). We used the Interpolation of Markov Chain approach to estimate the number of years underweight (BMI &lt; 20), normal weight (20 &lt; BMI &lt; 25), and overweight (25 &lt; BMI) individuals were expected to live without difficulty in activities of daily living (ADLs) or instrumental ADLs. Results We found differences in life and health expectancies across the three weight categories. Underweight people were expected to live the shortest lives and spend the fewest years in an active state compared with normal and overweight individuals. Results remained unchanged even when accounting for educational attainment, smoking history, and a count of existing chronic conditions. Discussion Being underweight is associated with poor quality of life lived among Japanese older adults. This finding suggests the importance of maintaining proper weight and avoids nutritional risks at advanced ages.

scholarly journals The impact of obesity on surgical outcomes in patients undergoing emergency laparotomy for high-risk abdominal emergencies

BMC Surgery ◽  
2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Woubet Tefera Kassahun ◽  
Matthias Mehdorn ◽  
Jonas Babel
Keyword(s):  
High Risk ◽  
Surgical Outcomes ◽  
Unit Length ◽  
Normal Weight ◽  
Overweight And Obesity ◽  
World Health ◽  
Emergency Laparotomy ◽  
Morbidly Obese ◽  
Abdominal Emergencies ◽  
The Impact

Abstract Background Obesity has been shown to increase the rates of morbidity and occasionally mortality in patients undergoing nonbariatric elective surgery. However, little is known about the impact of obesity on outcomes after surgery for high-risk abdominal emergencies. Methods A single-center retrospective evaluation of outcomes in high-risk abdominal emergency patients categorized by body mass index (BMI) was conducted. Patient demographics, comorbidities, and operative details were analyzed. Patients with normal weight (BMI 18.5–24.9) served as comparators. Multivariable linear and logistic regression analyses were performed to assess the impact of obesity on surgical outcomes. Results In total, 886 patients with BMI < 18.5 (underweight; n = 50), 18.5–24.9 (normal weight; n = 306), 25–29.9 (overweight; n = 336) and ≥ 30 (obese; n = 194) based on the World Health Organization (WHO) weight classification criteria met the inclusion criteria. Compared to normal-weight patients, patients with overweight and obesity were older and more likely to be male. The rates of comorbidity (100% vs 91.2%, p =  < 0.0001), morbidity (77.8% vs 65.6%, p = 0.003), and in-hospital mortality (44.8% vs 30.4%, p = 0.001) were all higher in patients with obesity than in normal-weight patients. Patients with obesity had an increased intensive care unit length of stay (ICU LOS) (13 days vs 9 days, p = 0.019) and hospital LOS (21.4 days vs 18.1 days, p = 0.081) and prolonged ventilation (39.1% vs 19.6%, p = 0.003). As BMI deviated from the normal range, the morbidity and mortality rates increased incrementally, with the highest morbidity (87.9%) and mortality (54.5%) rates observed in morbidly obese patients (BMI ≥ 40). Conclusions Patients with obesity were the most likely to have coexisting conditions, experience postoperative complications, and die during the first admission following EL for high-risk abdominal emergencies.

scholarly journals Malocclusion in Children with and without Cleft Palate - A case - Control Study

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 308-312
Author(s):  
Thiviya Raaj ◽  
Vignesh Ravindran ◽  
Sri Sakthi D
Keyword(s):  
Cleft Palate ◽  
Case Control Study ◽  
Oral Disease ◽  
Health Concern ◽  
Control Group ◽  
Record Management ◽  
Major Health ◽  
Spss Software ◽  
The Difference ◽  
Control Study

There is a principle agreement that malocclusion is a major health concern as it is the third most common oral disease, next only to dental caries and periodontal disease. As it is a major challenge for even normally abled children to handle these problems, questions arise as to the difference in the extent or severity of manifestation of malocclusion in the oral cavity of patients with cleft palate. The study aims to determine the prevalence of malocclusion in children with and without cleft palate. A sample size of 18 case sheets was reviewed for malocclusion in children with cleft only. The data was obtained from record management software of a private dental institute. Data was analysed using SPSS software, and Mann-Whitney was done. The results were recorded. Children with cleft palate showed higher incidence of malocclusion when compared to children without cleft palate. Within the limitations of the present study, children with cleft palate (case) showed a higher incidence of malocclusion than the control group.

scholarly journals Characterizing Trends in Lung Cancer Mortality Attributable to Airborne Environmental Carcinogens

2021 ◽  
Vol 18 (24) ◽  
pp. 13162
Author(s):  
Mitchell Veith ◽  
Drury McAlarney ◽  
Xiaonan Xue ◽  
Thomas E. Rohan ◽  
H. Dean Hosgood
Keyword(s):  
Cancer Mortality ◽  
Death Rate ◽  
Lung Cancer Mortality ◽  
Health Concern ◽  
Environmental Carcinogens ◽  
Uncertainty Interval ◽  
Major Health ◽  
Global Age ◽  
The Impact ◽  
Global Population

Tracheal, bronchus, and lung (TBL) cancer is the leading cause of cancer death globally, but trends in TBL mortality attributable to tobacco, ambient particulate matter pollution (APMP), and household air pollution (HAP) were unequally distributed within global population subgroups over the last three decades. We used data from the Global Burden of Disease 2019 study to quantify the impact of sex, time, sociodemographic development index (SDI), and age for each exposure from 1990–2019. During that interval, tobacco dominated the TBL cancer mortality landscape, with its minimum global age-adjusted death rate of 16.71 deaths/100,000 (95% Uncertainty Interval (UI): 15.27–18.13) outstripping maximums of 3.85 deaths/100,000 (UI: 2.82–4.83) and 2.54 deaths/100,000 (UI: 1.69–3.54) for APMP and HAP, respectively. In 2019, tobacco male TBL death rates exceeded female rates by a factor of 4.4:1. Ratios of 1.9:1 for APMP and 2.1:1 for HAP were seen. Our analysis indicates that both-sex middle SDI and female low, low-middle, and high-middle SDI populations are suffering increasing tobacco TBL burden. Efforts producing successful global reductions in HAP-associated TBL mortality should continue, with attention to low SDI female death rate increases. Finally, except for high SDI populations, global APMP-attributable TBL cancer burden is increasing and represents a major health concern.

scholarly journals Effect of reagents used during detection and quantification of Ascaris suum in environmental samples on egg viability

2017 ◽  
Vol 76 (9) ◽  
pp. 2389-2400 ◽  
Author(s):  
Isaac Dennis Amoah ◽  
Poovendhree Reddy ◽  
Thor Axel Stenström
Keyword(s):  
Magnesium Sulphate ◽  
Ascaris Suum ◽  
Tween 80 ◽  
Ammonium Bicarbonate ◽  
Health Concern ◽  
Acetoacetic Acid ◽  
Major Health ◽  
Recovery Percentage ◽  
The Difference ◽  
Detection And Quantification

Abstract Soil-transmitted helminths (STHs) are a major health concern globally. Infection is mostly through contact with contaminated water, food or soil. Therefore to break the cycle of viable transmission STH eggs must be quantitatively detected in the environment. The effect of different reagents on the viability of Ascaris suum eggs during laboratory detection and quantification was assessed and different incubation solutions compared. Sulphuric acid gave a slightly higher recovery percentage of viable eggs (91.2%) than distilled water (90.0%) and 0.5% formalin (87.6%), although the difference was not statistically significant (p &gt; 0.05). Acetoacetic acid, ethyl acetate, ammonium bicarbonate, zinc sulphate, magnesium sulphate and Tween 80, are reagents widely used in test protocols for the detection and quantification of STH eggs. Eggs were exposed to these reagents for different time durations. Acetoacetic acid resulted in the highest loss of viability (3.4 ± 0.7% viable), while magnesium sulphate resulted in the least effect (88.5 ± 1.2% viable). In conclusion the use of the selected reagents in the detection of these eggs was found to affect the viability of exposed eggs, especially during prolonged exposures. Therefore we recommended that eggs be exposed for ≤5 minutes, to reduce the risk of viability loss.

Earlier Onset of Maternal Excess Adiposity Associated with Shorter Exclusive Breastfeeding Duration

2018 ◽  
Vol 35 (2) ◽  
pp. 292-300 ◽  
Author(s):  
Misty A. W. Hawkins ◽  
Janna Colaizzi ◽  
Sarah Rhoades-Kerswill ◽  
Emily D. Fry ◽  
Natalie G. Keirns ◽  
...  
Keyword(s):  
Exclusive Breastfeeding ◽  
Online Survey ◽  
Normal Weight ◽  
Excess Weight ◽  
Analysis Of Covariance ◽  
Breastfeeding Duration ◽  
Snowball Sampling ◽  
Cross Sectional ◽  
Excess Adiposity ◽  
The Impact

Background: Exclusive breastfeeding for 6 months is recommended; however, women with obesity have lower exclusive breastfeeding rates than their normal weight peers. The impact of the timing of maternal excess adiposity onset is unknown. Research aim: We examined whether the timing of onset of excess weight was related to exclusive breastfeeding duration. Methods: Snowball sampling was used for the cross-sectional Breastfeeding Opinions, Outcomes, Behaviors, and Services online survey. The sample was 1,570 mothers who reported their breastfeeding and weight history. Exclusive breastfeeding duration (for first biological child only) was calculated in months and dichotomously (0=< 6 months exclusive breastfeeding; 1=⩾ 6 months exclusive breastfeeding). Participants self-reported their excess weight onset (0=before/during puberty or 1=after puberty). Results: Analysis of covariance results indicated that earlier onset of excess weight was associated with shorter exclusive breastfeeding ( F (1, 1518) = 11.29, p<.001, η2=.01). Those with excess adiposity onset before or during puberty were 1.6 times more likely to experience exclusive breastfeeding failure (< 6 months exclusive breastfeeding) than those with onset after puberty ( OR = 1.57, β = .46, Wald = 11.81, p = .001). Conclusion: Earlier onset of excess adiposity had an adverse influence on exclusive breastfeeding duration. Women with a history of excess adiposity before or during puberty who want to breastfeed may require additional intervention to promote their breastfeeding success.

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