Differentiating between cold agglutinins and rouleaux: a case series of seven patients

Perfusion ◽  
2017 ◽  
Vol 33 (2) ◽  
pp. 164-169 ◽  
Author(s):  
Michele Heath ◽  
Julie Walker ◽  
Atilio Barbeito ◽  
Adam Williams ◽  
Ian Welsby ◽  
...  

We present a case series of seven patients with suspected cold agglutinin antibodies, discovered after initiation of bypass. Laboratory analysis of blood samples intraoperatively determined the cause of the aggregation to be rouleaux formation in three of the patients and cold agglutinins in the other four.

2021 ◽  
Vol 5 (5) ◽  
Author(s):  
Yusuke Shimahara ◽  
Satsuki Fukushima ◽  
Shin Yajima ◽  
Naoki Tadokoro ◽  
Takashi Kakuta ◽  
...  

Abstract Background The surgical treatment for postinfarction ventricular septal defect (VSD) remains challenging, especially in emergency cases. Several authors have reported the efficacy of a sandwich patch VSD repair via a right ventricular (RV) incision. However, this procedure remains uncommon, and its efficacy is still unknown, especially when performed under an emergency. Case summary We were able to perform sandwich patch VSD repair via an RV incision on seven consecutive patients with VSD following an ST-segment elevation myocardial infarction (STEMI) from March 2017 to December 2019. Bovine pericardial patches were used for sandwich patches. Two patients developed inferior STEMI, and the other patients developed anterior STEMI. Six patients received intra-aortic balloon pump prior to surgery, and the other received extracorporeal membrane oxygenation with Impella. The interval between the diagnosis of VSD and surgery was within 1 day in all patients except one (5 days). All seven patients underwent VSD repair in the emergency status. Four patients underwent concomitant coronary artery bypass grafting. The hospital mortality rate was 14.3% (1/7). Early postoperative transthoracic echocardiography revealed that only one patient developed more than trace residual shunt. The postoperative right atrial pressure was not significantly elevated at ≤12 mmHg in all patients. No patient developed early postoperative prolonged low cardiac output syndrome. Discussion In patients with postinfarction VSD, a sandwich patch VSD repair via an RV incision is a promising procedure with a low incidence of residual shunt development and hospital mortality, even in emergency cases.


2002 ◽  
Vol 3 (3) ◽  
pp. 221-225

In recent months a bumper crop of genomes has been completed, including the fission yeast (Schizosaccharomyces pombe) and rice (Oryza sativa). Two large-scale studies ofSaccharomyces cerevisiaeprotein complexes provided a picture of the eukaryotic proteome as a network of complexes. Amongst the other stories of interest was a demonstration that proteomic analysis of blood samples can be used to detect ovarian cancer, perhaps even as early as stage I.


1980 ◽  
Vol 94 (1) ◽  
pp. 95-104 ◽  
Author(s):  
G. J. Rowlands

SummaryBlood samples were taken at 9, 10 and 11 weeks of age from 230 male Hereford × Friesian calves, the progeny of 12 Hereford bulls. Concentrations of blood glucose, serum albumin, inorganic phosphate and sodium were measured and correlated with body weights and growth rates until slaughter at 19½ months of age.Correlations between growth rates and glucose concentrations (0·44) and between growth rates and albumin concentrations (0·38) were observed until 4 months of age. Similar correlations between body weights and blood glucose or albumin concentrations persisted until 6 months of age. By 10 months, however, the correlations had begun to decline, and by slaughter they had become insignificant.Correlations between growth rates and inorganic phosphate or sodium concentrations were smaller, and also decreased with age.The effect of hypoglycaemia on growth rate was compared with the effect of enzootic pneumonia. Although the 10% of calves with the lowest glucose concentrations were growing 24% more slowly than the other calves at the time of sampling, this growth depression was not related to pneumonia, and they subsequently made up for most of the early loss of growth.Three blood samples were also taken from 22 Hereford bulls. No significant correlations were observed between the blood composition of the bulls and the body weights or weight gains of their progeny.


2021 ◽  
Vol 9 (11) ◽  
pp. 422-430
Author(s):  
Achoh Mardochee Ephraim ◽  
◽  
Agadjihouede Hyppolite ◽  
Gangbe Luc ◽  
Aizonou Romaric ◽  
...  

The present study aim to estimate the ratio of aquaculture in the phosphorus and nitrogen concentrations determined in the Toho - Todougba lagoons. For this purpose, the two lagoons were subdivided into 7 stations for the determination of phosphorus and nitrogen concentrations in the water column. Production data from 2017 to 2019 were collected from the Direction of the Ficheries Production and from the literature. Data for 2020 were collected directly from fish farmers. Annual tilapia production was estimated by year and the amounts of phosphorus and nitrogen released from aquaculture are deduced based on the ratio of Montanhini Neto & Ostrensky (2013). The concentration of each of these nutrients was estimated by station and compared to the concentration determined by laboratory analysis of the water. This methodology shows that the amount of phosphorus and nitrogen released to the environment varies from 0.49 mg/L to 0.18 mg/L for phosphorus and from 1.53 mg/L to 0.58 mg/L for nitrogen. The lowest values are obtained in 2020 and differ significantly from the other years (p <0.05). The quantity of phosphorus discharged is higher at the high production stations (Tonon 0.20 mg/L and Lokohoue 0.11 mg/L). Some of this is stored in the sediment. The nitrogen generated by aquaculture is significantly lower than the average determined in water (p <0.05). However, the concentration determined is still related to the amount of organic matter released due to aquaculture. Although aquaculture is not the only source of nutrient release to water, strategies for aquaculture with less nutrient release should be determined.


2016 ◽  
Vol 13 (4) ◽  
pp. 639-648
Author(s):  
Baghdad Science Journal

This study was designed to investigate the effect of the Clenbuterol drug in some physiological parameters of Liver, Kidney function and lipidprofie concentration. Fourty adult male rabbits were used in this study. The animals were randomly divided into four groups,the first group was given distilled water (control) ,while the other third groups were given (2,4,6 µg/kg) of Clenbuterol drug for 30 days. Blood samples were collected after 14 and 30 days of the treatment for biochemical study. Drug caused non significant increase(P


Author(s):  
TALAT KILIC ◽  
Sebnem Kilic ◽  
Nurcan Kirici Berber ◽  
Ayten Gunduz ◽  
Yasemin Ersoy

Objectives: Studies have shown that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is primarily transmitted from person to person via airborne droplets. It is unclear whether it can be shed into human milk and transmitted to a child via breastfeeding.We investigated the presence of SARS-CoV-2 RNA in human milk samples of 15 mothers with coronavirus disease 19(COVID-19) and in the throat swab samples of their infants. Methods: This is a prospective observational study in which breast milk samples were collected from 15 mothers with COVID-19. The presence of SARS-CoV-2 RNA in the whole human milk samples of the patients was investigated using RT-qPCR. All of the infants underwent a clinical follow-up during their 14-day isolation and their throat swab samples were tested for SARS-CoV-2 RNA. Results: Of 15 mothers with COVID-19, SARS-CoV-2 RNA was detected in milk samples from 4 mothers. The throat swab samples from these mothers’ infants were found to be positive for SARS-CoV-2 RNA. Three of the four mothers were breastfeeding. In addition, during the 14-day isolation, all but three of the mothers breastfed their infants. Of the 12 breastfed infants, while the test for SARS-CoV-2 RNA in throat swab samples was negative in six of the infants, the other six infants, who had mild COVID-19 symptoms, tested positive for SARS-CoV-2 RNA.Clinical outcomes of all mothers and infants were uneventful. Conclusion: To our knowledge, this is the first case series with the largest number of cases with SARS-CoV-2 RNA positivity in human milk samples of mothers with COVID-19. However, we believe that the benefits of breastfeeding may outweigh the risk of SARS-CoV-2 infection in infants


2007 ◽  
Vol 4 (4) ◽  
pp. 612-616
Author(s):  
Baghdad Science Journal

Blood samples of One hundred and twenty patients from different hospitals in Baghdad infected with hydatidosis in different sites of the body (Liver, Lung, multiorgans and kidney) were collected for this study. On the other hand, 30 healthy individuals were included as a control group. This study was conducted to evaluate the effect of this disease on the serum protein profile of the patients using electrophoresis. The results revealed four different protein banding patterns with difference in number of bands and their molecular weights in comparison to the control group, and these differences depended on the site of infection. However the data showed a presence of the same band in all patients with different site of infection.


2025 ◽  
Vol 77 (04) ◽  
pp. 6511-2025
Author(s):  
SONGUL ERDOGAN ◽  
KEREM URAL ◽  
HASAN ERDOGAN ◽  
DENIZ ALIC URAL ◽  
MEHMET GULTEKIN ◽  
...  

In the present study, the aim was to determine alteration of NEFA, calcium and vitamin D3 levels in cow and calf pairs at parturition as well as correlation between each parameter levels. For this purpose, a cow-side device employing the enzymatic colorimetric method was used for measurement of NEFA and calcium levels. On the other hand, serum 25(OH)D3 analysis was performed using the fluorescence immunochromatographic method at the laboratory in the Faculty. Blood samples were taken from Vena jugularis of 15 Simmental cow and calf pairs immediately after parturition and placed in serum and heparinized tubes. In cow and calf pairs, concentration of vitamin D3 (15.6-120 and 31.8-120 ng/mL, respectively), NEFA (0.12-1.2 and 0.09-0.8 mmol/L, respectively) and calcium (1.8 ± 0.9 and 2.2 ± 0.6 mmol/L, respectively) were determined. There was no significant correlation between NEFA, Ca, and vitamin D3 in cows and calf pairs. Taking into account several co-factors that influenced test results, which could not easily be excluded, further studies may be warranted with larger cow-calf pair populations. In conclusion, vitamin D3 concentration in calves is not affected by the negative energy balance of dams in the parturition period.


2021 ◽  
pp. 1098612X2110548
Author(s):  
Catherine Tindale ◽  
Filippo Cinti ◽  
Matteo Cantatore ◽  
Alistair Freeman ◽  
Leonardo Cavaliere ◽  
...  

Case series summary Lung lobe torsion is rare in cats. The aim of this multi-institution retrospective study was to describe clinical and diagnostic findings, treatments and outcomes of lung lobe torsion (LLT) in 10 cats. Dyspnoea and tachypnoea were the most common clinical signs. Pleural effusion was present in nine cats at presentation. Fluid analysis confirmed chylothorax in three cats. Nine cats underwent CT and five cats had thoracic radiographs taken. A diagnosis was made preoperatively in six cats, while in the other four cats it was made at exploratory thoracotomy. Affected lung lobes were the right cranial (n = 4/11), left cranial (n = 4/11) and right middle (n = 3/11). One cat had a concurrent torsion of two lung lobes. Lung lobectomy was successfully performed in all cases. Based on clinical, diagnostic and lung histopathology findings, three cats had idiopathic and seven cats secondary LLT. Intraoperative complications included hypotension and hypothermia in four and five cats, respectively. Postoperative complications occurred in six cats and lead to euthanasia or death in four cats, whereas complications resolved in the other two cats. Three cats were euthanased within 5 weeks of discharge. For the three cats surviving long term, including one euthanased at 252 days postoperatively, owner-described outcomes and quality of life were considered good to excellent. Relevance and novel information Secondary LLT associated with underlying thoracic pathology was associated with high complication rates and poor outcomes. Long-term outcomes of cats undergoing surgery for LLT and surviving the perioperative period were deemed good to excellent.


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