scholarly journals Steady exercise improves hand grip and leg muscle strength in hemodialysis patients

2021 ◽  
Vol 17 (6) ◽  
pp. 435-443
Author(s):  
Ran-hui Cha ◽  
Geum Sil Lee

Sarcopenia due to chronic inflammation and biochemical disturbances in chronic kidney disease is severer and more prevalent in hemodialysis (HD) patients. We longitudinally evaluated the hand grip strength (HGS) and leg muscle strength (LMS) and evaluated the role of exercise in muscle strength in HD patients. We screened (January, n= 127) and followed up (June, n= 110 and December 2020, n= 104). HGS and LMS at single center by using digital hand and leg dynamometer. HGS (24.2 kg vs. 15.5 kg) and LMS (32.8 kg vs. 22.5 kg) were better in men (P<0.001 and P<0.001, respectively). Older patients ( ≥ 60 years) showed decreased LMS than others in women (P=0.01). Patients who performed steady home- or hospital-based exercise showed marginally higher HGS (23.1 kg vs. 19.8 kg, P=0.07) and significantly higher LMS (33.7 kg vs. 25.9 kg, P=0.004). Steady exercise improved LMS throughout the study period (30.3 kg vs. 33.2 kg from Jan to Jun 2020, P=0.004; 30.3 kg vs. 34.2 kg from Jan to Dec 2020, P=0.014). Multiple linear regression analysis proved steady exercise was independently associated with better HGS and LMS. Steady exercise showed greater impact on LMS in male patients with longer HD vintage (≥ 44 months) and on HGS in younger male patients with shorter HD vintage (< 44 months). Steady exercise was an important determinant of muscle strength in HD patients. We need to encourage patients to steadily perform regular home- or group-exercise before sarcopenia develops.

2021 ◽  
Vol 36 (11) ◽  
Author(s):  
Ran-hui Cha ◽  
Geum Sil Lee ◽  
Ju Yeon Yoo ◽  
Oe Bog Rhee ◽  
Yong Duk Jeon

2017 ◽  
Vol 4 (1) ◽  
pp. 189-215
Author(s):  
Yoiz Shofwa Shafrani

Perkembangan dunia perbankan syariah tidak lepas dari peran para nasabah yang memberikan kepercayaan terhadap pihak perbankan untuk penyimpanan asset keuangannya. Faktanya banyak kelompok nasabah yang memutuskan untuk menjadi nasabah di perbankan syariah karena faktor religiusitasnya. Faktor lain yang dapat ikut mempengaruhi keputusan nasabah adalah kualitas produk. Di mana kualitas produk merupakan karakteristik yang melekat dari suatu produk. Kemungkinan yang terjadi bahwa kebanyakan nasabah pada perbankan syariah juga masih merupakan nasabah perbankan konvensional.Tujuan yang ingin dicapai dalam penelitian ini adalah untuk mengetahui pengaruh kualitas produk dan tingkat religiusitas nasabah terhadap keputusan nasabah untuk menyimpan dananya atau tidak di BSM Cabang Purwokerto. Alat analisis yang digunakan adalah analisis regresi linier berganda, dengan jumlah sampel 100 nasabah. Diperoleh hasil Y = 5,046 + 0,101X1 + 0,218X2. Berdasarkan uji F yang sudah dilakukan maka dapat diketahui bahwa variabel kualitas produk dan religiusitas secara bersama – sama berpengaruh terhadap keputusan nasabah untuk menyimpan dananya di BSM Cabang Purwokerto. Berdasarkan uji t yang sudah dilakukan dapat diketahui bahwa secara partial baik variabel kualitas produk maupun variabel religiusitas berpengaruh terhadap keputusan nasabah untuk menyimpan dananya di BSM Cabang Purwokerto. The progress of the Islamic bank cannot be separated from the role of its customers who give trust to the bank to deposit their financial assets. It is a fact many groups of customers decide to be the customers of the Islamic bank because of their religiosity. The other influences factor of a customer’s decision is the quality of the product. The aim of this research was to determine the effect of product quality and level of customers’ religiosity towards customers’ decision whether to keep their funds in Syariah Mandiri Bank, Branch of Purwokerto, or not. The analytical tool used was multiple linear regression analysis, with a sample of 100 customers. The results indicate Y = 5,046 + 0,101X1 + 0,218X2. Based on F, it can be seen that both variables of product quality and religiosity simultanously affect the customers’ decision to keep theirfunds in BSM Branch of Purwokerto. Based on t test, it can be seen that independently, either variable of product quality or variables of religiosityinfluences the customers’ decision to keep their funds in BSM Branch of Purwokerto.


2019 ◽  
Vol 14 (2) ◽  
pp. 95
Author(s):  
Melia Frastuti ◽  
Dimas Pratama Putra ◽  
Erfan Effendi

Abstract     Almsgiving is one of the pillars supporting the upholding of Islam as the obligation for the adherents to improve horizontal relations between fellow humans and strengthen vertical relations with Allah SWT. The implementation of Islamic Social Responsibility (ISR) of the Islamic Bank gives a positive assessment in sharia agreement, justice and equality, responsibility for work, welfare, guarantee of nature preservation and benevolent assistance that is not profit-oriented.Proper almsgiving management and ISR implementation make Islamic banks trusted by the public in terms of service quality, satisfaction and loyalty of Muzzaki. It reduces bad images, and provides relevant impacts on social welfare and the progress of the era. The data analysis used to test the hypotheses is Multiple Linear Regression analysis. The data is collected by distributing questionnaires to Commissioners and Directors at 14 (fourteen) Islamic Commercial Banks spread throughout Indonesia. The result of this study shows partially prove the role of Islamic bank commissioners in the amsgiving management only, while the importance of the role of directors in Islamic banks in almsgiving management and the implementation of ISR partially. Keywords: Islamic Bank, Commissioners, Directors, Almsgiving and ISR


2021 ◽  
Author(s):  
Yu Qi ◽  
Yuan-Yuan Wang ◽  
Wei Wang ◽  
Xu-Ze Liu ◽  
Jing Liu ◽  
...  

Abstract Background To investigate the effect of syphilis infection on the microstructure of white matter (WM) in HIV-infected male patients through comparing the differences of WM between HIV-infected male patients with and without syphilitic infection using diffusion tensor imaging (DTI).Methods 27 HIV-infected male patients with current syphilis or a history of syphilis (HIV+/syphilis+) and 29 HIV-infected male patients without syphilis co-infection history (HIV+/syphilis-) were enrolled. All patients received DTI and comprehensive neuropsychological assessment. Clinical data were compared between the two groups with T-test, Mann-Whitney U Test and Chi-square Test. Tract-based spatial statistics (TBSS) was adopted to analyze the DTI metrics. Multiple linear regression analysis was conducted to investigate the relationships between DTI metrics and clinical variables and cognitive performance. Results In the HIV+/syphilis+ group, decreased AD was found in the right superior corona radiata (SCR-R) and body of corpus callosum (BCC); increased RD was found in the bilateral posterior corona radiata (PCR), the right posterior thalamic radiation (PTR-R), the left SCR (SCR-L), splenium of corpus callosum (SCC) and BCC; decreased FA was found in multiple regions. AD in BCC was negatively correlated with CD4/CD8 ratios. AD in SCR-R was positively correlated with CD4/CD8 ratios. Patients in HIV+/syphilis+ group had a lower score in complex motor skills (CMS). RD in SCC and SCR-L was negatively correlated with CMS; RD in PTR-R was positively correlated with CMS. AD in SCR-R was positively correlated with CMS. Conclusions Compared with patients simply infected with HIV, the integrity of WM is more seriously impaired in HIV-infected patients with syphilis co-infection, and it may accelerate the impairment of cognitive function.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Dan Liu ◽  
Zhiding Wang ◽  
Huijuan Wang ◽  
Feifei Ren ◽  
Yanqin Li ◽  
...  

Abstract Lymphocyte apoptosis appears to play an important role in immunodysfunction in sepsis. We investigated the role of miR-223 in cell proliferation and apoptosis to identify potential target downstream proteins in sepsis. We recruited 143 patients with sepsis and 44 healthy controls from the Chinese PLA General Hospital. Flow cytometry was used to sort monocytes, lymphocytes, and neutrophils from fresh peripheral blood. A miR-223 mimic and inhibitor were used for transient transfection of Jurkat T cells. Quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) was used to assess expression of the miRNAs in cells. Western blot analysis was performed to measure protein expression. We evaluated the cell cycle and apoptosis by using flow cytometry (FCM) and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL). Expression of miR-223 was significantly higher in the survivor group than in the nonsurvivor group. Multiple linear regression analysis revealed that SOFA scores correlated negatively with miR-223 and monocyte counts, with β coefficients (95% CI) of − 0.048 (− 0.077, − 0.019) and − 47.707 (− 83.871, − 11.543), respectively. miR-223 expression also correlated negatively with the percentage of apoptosis in lymphocytes. The rate of apoptosis in the miR-223 mimic group was significantly lower than that of the negative control, with an adverse outcome observed in the miR-223 inhibitor group. We also found that miR-223 enhanced the proliferation of Jurkat T cells and that inhibiting miR-223 had an inhibitory effect on the G1/S transition. We conclude that miR-223 can serve as a protective factor in sepsis by reducing apoptosis and enhancing cell proliferation in lymphocytes by interacting with FOXO1. Potential downstream molecules are HSP60, HSP70, and HTRA.


2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Liqin Yin ◽  
Changfa Tang ◽  
Xia Tao

Objective. To study the criterion-related validity of simple muscle strength test (SMST) indicators and assess whole body muscle strength in Chinese children aged 10 to 12 years old.Methods. Two hundred and forty children were equally divided into four groups in different genders and residences. The SMST indicators (hand-grip, knee bent push-up, back muscle strength, sit-up, leg muscle strength, and standing long jump) were tested. We set up the total level of the whole-body muscle strength (Ftotal) through testing isokinetic muscle strength of the six joints’ flexion and extension movements. Pearson correlation analyses were used to analyze the correlation between the SMST indicators and theFtotal.Results.(1)Leg muscle strength and back muscle strength demonstrated the highest validity scores. Sit-ups, hand grip, and standing long jump demonstrated the lowest validity scores.(2)Leg muscle strength had the highest validity for males, but back muscle strength had the highest validity for females.Conclusions. Back muscle strength and leg muscle strength can give the highest validity of assessing whole body muscle strength, and also has higher validity in both the urban and rural children. For urban children, but not rural, the knee bent push-up also has a high validity indicator.


2011 ◽  
Vol 38 (4) ◽  
pp. 680-684 ◽  
Author(s):  
CHINAMI OYABU ◽  
AKIO MORINOBU ◽  
DAISUKE SUGIYAMA ◽  
JUN SAEGUSA ◽  
SHINO TANAKA ◽  
...  

Objective.To clarify the role of platelet-derived microparticles (PDMP), which are small vesicles with thrombotic and immunological properties, in systemic lupus erythematosus (SLE), systemic sclerosis (SSc), dermatomyositis/polymyositis (PM/DM), and mixed connective tissue disease (MCTD).Methods.Plasma levels of PDMP were measured by ELISA, and compared among patients with one of the 4 diseases. Association of PDMP levels with clinical characteristics and medication of the patients was also examined.Results.PDMP levels were higher in patients with MCTD and SSc than in controls. Multiple linear regression analysis revealed that patients with Raynaud’s phenomenon (RP) showed higher PDMP levels than those without. PDMP levels in individual patients did not fluctuate significantly over several months.Conclusion.PDMP level is associated with MCTD, SSc, and RP, and could be a novel marker for RP.


2019 ◽  
Vol 6 (01) ◽  
Author(s):  
Petrus Kondoallo ◽  
J.M.V. Mulyadi

ABSTRACT This study examines the role of service performance on the effect of Investment, Operational Costs and Financial Performance on the Income of BLU hospitals, the sample consisted of eighteen hospitals with multiple linear regression analysis techniques. The classic assumption test results show that the model tested is normally distributed, there is no multicollinarity and there is no heterokedacity and the autocorrelation model does not occur. Testing is done with two test models, namely the first test of the effect of investment, operational costs and financial performance on service performance which results simultaneously all dependent variables influence the independent variable while only financial performance partially influences the service performance while investment and influential operational costs do not significant, then the second test partially shows that operational costs and service performance have a significant effect on income, this study also uses path analysis where the results show indirectly investment and financial performance through service performance has a significant influence on income. ABSTRAK Penelitian ini menguji peran kinerja pelayanan pada pengaruh Investasi, Biaya Operasional dan Kinerja Keuangan terhadap Pendapatan Rumah Sakit BLU, sampel terdiri delapan belas Rumah Sakit dengan teknik analisis regresi linier berganda. Hasil uji asumsi klasik menunjukkan model yang diuji berdistribusi normal, tidak terdapat multikolienaritas dan tidak terjadi heteroskedastisitas serta model regresi tidak terjadi autokorelasi. Pengujian dilakukan dengan dua model pengujian yaitu pengujian pertama Pengaruh Investasi, Biaya Operasional dan Kinerja Keuangan terhadap Kinerja Pelayanan yang hasilnya secara simultan seluruh variabel dependen berpengaruh terhadap variabel independen sedangkan secara parsial hanya Kinerja Keuangan yang berpengaruh signifikan terhadap Kinerja Pelayanan sementara Investasi dan Biaya Operasional berpengaruh tidak signifikan, kemudian pengujian kedua secara parsial menunjukkan Biaya Operasional dan Kinerja Pelayanan berpengaruh signifikan terhadap Pendapatan. Penelitian ini juga menggunakan analisis jalur yang hasilnya menunjukkan secara tidak langsung Investasi dan Kinerja Keuangan melalui Kinerja Pelayanan mempunyai pengaruh signifikan terhadap Pendapatan. JEL Classification: M40, H20


2019 ◽  
Vol 5 (2) ◽  
pp. 247-260
Author(s):  
Rahmat Daim Harahap ◽  
Muhammad Ikhsan Harahap ◽  
Meilya Evita Syari

The government hold significant role in the implementation of fiscal economy policy to achieve the main goal of development: high economic growth, decrease of unemployment, and control of inflation, income and expenditure that can be used in increasing economic growth. Regional incomes are locally-generated revenue, General Allocation Fund. Meanwhile, cost is regional expenditures. Thus, this study is aimed to determine the influence of the General Allocation Fund and Regional income on economic growth with the role of Regional Expenditure as an intervening variable. The study was located on Deli Serdang Regency. This is a quantitative research with multiple linear regression analysis by using SPSS. The result shows that General Allocation Fund and Regional income influence the economic growth, meanwhile regional expenditures mediates between General Allocation Fund and Regional income on economic growth.


2020 ◽  
Vol 4 (2) ◽  
pp. 93-108
Author(s):  
Poppy Yuanita ◽  
Yeremias Torontuan Keban

ABSTRAKPengelolaan sampah telah menjadi salah satu permasalahan yang jamak terjadi di perkotaan. Produksi sampah meningkat seiring dengan pertambahan penduduk dan jumlah konsumsi serta gaya hidup masyarakat, namun tidak diimbangi dengan pengelolaan sampah yang ramah lingkungan dan berkelanjutan. Untuk itu, diperlukan upaya untuk mulai mengurangi, memisahkan, dan memanfaatkan sampah. Program Kang Pisman adalah konsep yang diperkenalkan oleh Pemerintah Kota Bandung untuk mengatasi masalah tersebut.Tujuan dari penelitian ini adalah mengevaluasi efektivitas Program Kang Pisman dan mengetahui faktor yang memepengaruhinya. Evaluasi efektivitas perlu dilakukan untuk mengetahui apakah hasil dari program tersebut sudah sesuai dengan tujuan awal perencanaan. Metode dalam penelitian ini adalah deskriptif kuantitatif dengan menggunakan instrumen pengumpulan data berupa kuesioner terhadap 98 rumah yang menjadi sampel penelitian. Efektivitas Program Kang Pisman penting untuk diteliti begitu juga faktor yang berpengaruh terhadap program tersebut agar dapat digunakan sebagai bahan evaluasi program dan menjadi masukan dalam membuat kebijakan lebih lanjut tentang pelaksanaan program. Hasil skoring variabel efektivitas menunjukkan bahwa Program Kang Pisman ada pada tingkatan cukup efektif. Untuk mengetahui faktor yang mempengaruhi efektivitas program, dilakukan analisis regresi linear berganda dengan enam variabel bebas, yaitu komitmen pemerintah, kemudahan menjalankan program, kinerja petugas pelaksana, ketersediaan sarana dan prasarana, peran Lembaga Swadaya Masyarakat (LSM) dan persepsi masyarakat. Faktoryang berpengaruh signifikan terhadap efektivitas adalah persepsi masyarakat dan kemudahan dalam menjalankan program.Kata kunci: evaluasi efektivitas, kang pisman, pengelolaan sampah. ABSTRACTSolid waste management is one of the global problems faced by urban areas. Waste generation increased according to population growth and followed by consumption and lifestyle, however not balanced with the management of waste that is environmentally friendly and sustainable. We need to reduce, sort, and reuse the waste. The Kang Pisman Program is a concept introduced by the Bandung City Government to overcome this problem. The objectives of this research are to evaluate the effectiveness of the program and its influential driving factors. Evaluation of effectiveness needs to be held to find out wheater the results of the program are following the original purpose. This research uses a quantitative descriptive method with a questionnaire instrument to interview 98 houses as a sampling. The effectiveness of the Kang Pisman Program is essential to evaluate as well as the factors that influence the program so that it can be used as a program evaluation material and be input in making further policy regarding program implementation. The scoring result shows that Kang Pisman Program is at quite effective level. To find out the factors that influence the effectiveness of the program, multiple linear regression analysis was carried out with six independent variabels, namely goverment commitment, ease of running the program, the staff performance, infrastructure, the role of NGOs and community perceptions. Factors that have a significant influence on effectiveness are community perception and ease in running the program.Keywords: effectiveness evaluation, kang pisman, waste management.


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