The Association between Depression and the Dietary Intakes of Tryptophan and Vitamin B6

2021 ◽  
Vol 9 (1) ◽  
pp. 4-18
Author(s):  
Haitham Jahrami
Keyword(s):  
Vitamin B6 ◽  
Dietary Intakes

Vitamin B6 During Pregnancy

1982 ◽  
Vol 1 (2) ◽  
pp. 78-84 ◽  
Author(s):  
Barbara Pickard
Keyword(s):  
Oral Contraceptive ◽  
Vitamin B6 ◽  
Hormonal Changes ◽  
Dietary Intakes ◽  
Contributing Factors ◽  
Maternal Vitamin ◽  
Contraceptive Usage ◽  
Synthetic Vitamin ◽  
Daily Diet ◽  
Vitamin B6 Deficiency

A vitamin B6 deficiency develops during pregnancy and contributing factors include: a disturbance in vitamin B6 metabolism caused by increasing levels of oestrogens; increasing fetal demand for vitamin B6; a disturbance in vitamin B6 status caused by oral contraceptive usage prior to conception; a deficient intake of vitamin B6. Hormonal changes and increasing fetal requirements impose considerable stress on maternal vitamin B6 status but are the inevitable consequences of pregnancy. In contrast, longterm use of oral contraceptives before pregnancy and an inadequate vitamin B6 intake, both prior to and during pregnancy, are potentially avoidable. Dietary intakes of vitamin B6 in many women fall well below the recommended 1.5–2.0mg/day before pregnancy and 2.5mg/day during pregnancy. Although supplementation with synthetic vitamin B6 is advocated by many, much greater emphasis should also be placed on a wholesome, healthy diet. Examples are given of foods high and low in vitamin B6 and of a daily diet providing 2.5mg of vitamin B6.

scholarly journals The association between dietary total antioxidant capacity and glioma among Iranian adults

2020 ◽  
Author(s):  
Marzieh Heydari ◽  
Mehdi Shayanfar ◽  
Giuve Sharifi ◽  
Parvane Saneei ◽  
Omid Sadeghi ◽  
...  
Keyword(s):  
Vitamin C ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Vitamin B6 ◽  
Inverse Association ◽  
Dietary Intakes ◽  
Antioxidant Power ◽  
Total Antioxidant ◽  
Β Carotene ◽  
Dietary Total Antioxidant Capacity

Abstract Background: Dietary total antioxidant capacity (TAC) has been investigated in relation to different types of cancer. However, data on the link between dietary TAC and glioma are scarce and conflicting. We assessed the relation between dietary TAC and risk of glioma among Iranian adults. Methods: This investigation was a hospital-based case-control study that was done in Tehran between November 2009 and September 2011. Cases were individuals with pathologically confirmed glioma that were diagnosed during the last month (n=128). Controls were individuals, aged between 20 and 75 years, who were hospitalized or were outpatients referred to other wards of the same hospitals (n=256). Usual dietary intakes of participants during the preceding year were examined using a food frequency questionnaire. Data on dietary TAC from foods was gathered from published databases that provided the antioxidant capacity for each food item, measured by ferric reducing antioxidant power (FRAP). Results: Mean age of study participants in case and control groups was 43.4 and 42.7 y, respectively. Compared with participants in the lowest quartile, those in the highest quartile of dietary TAC had a lower odds of glioma (OR: 0.28, 95% CI: 0.15-0.45). This association was strengthened when potential confounders were taken into account (OR: 0.13; 95% CI: 0.05-0.35). Such inverse association was also seen for men (OR: 0.05, 95% CI: 0.01-0.19), but not for women. Furthermore, significant inverse associations were seen between dietary intakes of vitamin C (OR for Q4 vs. Q1: 0.14, 95% CI: 0.05-0.36; P-trend<0.01), vitamin B6 (OR for Q4 vs. Q1: 0.35, 95% CI: 0.13-0.97; P-trend=0.02) and β-carotene (OR for Q3 vs. Q1: 0.43, 95% CI: 0.19-0.98; P-trend=0.57) and glioma, after controlling for potential covariates. Conclusion: We found that dietary TAC as well as dietary intake of vitamin C, vitamin B6 and β-carotene was inversely associated with odds of glioma in Iranian adults.

scholarly journals Association of dietary intakes of vitamin B12, vitamin B6, folate, and methionine with the risk of esophageal cancer: the Japan Public Health Center-based (JPHC) prospective study

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Paramita Khairan ◽  
Tomotaka Sobue ◽  
Ehab Salah Eshak ◽  
Ling Zha ◽  
Tetsuhisa Kitamura ◽  
...  
Keyword(s):  
Public Health ◽  
Esophageal Cancer ◽  
Dietary Intake ◽  
Prospective Study ◽  
Vitamin B12 ◽  
Health Center ◽  
Vitamin B6 ◽  
B Vitamins ◽  
Dietary Intakes ◽  
Public Health Center

Abstract Background B vitamins and methionine are essential substrates in the one-carbon metabolism pathway involved in DNA synthesis and methylation. They may have essential roles in cancer development. We aimed to evaluate the associations of dietary intakes of vitamin B12, vitamin B6, folate, and methionine with the risk of esophageal cancer (EC) using data from the Japan Public Health Center-based Prospective Study. Methods We included 87,053 Japanese individuals who completed a food frequency questionnaire and were followed up from 1995–1998 to 2013 and 2015. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated by Cox proportional-hazard regression across quintiles of dietary intakes of B vitamins and methionine. Results After 1,456,678 person-years of follow-up, 427 EC cases were documented. The multivariable HR (95% CI) of incident EC in the highest versus lowest quintile of dietary intake of vitamin B12 was 1.75 (1.13–2.71; p-trend=0.01). Stratification analysis based on alcohol consumption showed that higher dietary intakes of vitamin B12 and methionine were associated with an increased risk of EC among never-drinkers; HRs (95% CIs) were 2.82 (1.18–6.74; p-trend=0.009; p-interaction=0.18) and 3.45 (1.32–9.06; p-trend=0.003; p-interaction 0.02) for vitamin B12 and methionine, respectively. Meanwhile, there was no association between vitamin B12 and methionine intake with the risk of EC among drinkers. There were no associations between dietary intake of folate or vitamin B6 and the risk of EC. Conclusion Dietary intake of vitamin B12 was positively associated with the risk of EC in the Japanese population.

Higher vitamin B6 intake is associated with lower depression and anxiety risk in women but not in men: A large cross-sectional study

2020 ◽  
Vol 90 (5-6) ◽  
pp. 484-492 ◽  
Author(s):  
Marzi Kafeshani ◽  
Awat Feizi ◽  
Ahmad Esmaillzadeh ◽  
Ammar Hassanzadeh Keshteli ◽  
Hamid Afshar ◽  
...  
Keyword(s):  
Vitamin B6 ◽  
Total Population ◽  
Depression Scale ◽  
Cross Sectional Study ◽  
Anxiety And Depression ◽  
Dietary Intakes ◽  
Depression And Anxiety ◽  
Sectional Study ◽  
Cross Sectional ◽  
Increased Risk

Abstract. Objective: The prevalence of depression and anxiety is increasing worldwide. Diet as a modifiable factor for mental health has received great attention. The aim of the present study was to evaluate the association of vitamin B6 intake with depression and anxiety. Methods: This cross-sectional study was performed among 3362 adults in 2011. Anxiety and depression were evaluated using an Iranian validated version of the Hospital Anxiety and Depression Scale (HADS) questionnaire. Dietary intakes were evaluated by a validated 106 item self-administered Willett-format dish-based semi quantitative food-frequency questionnaire (DFQ). Results: The mean intake of vitamin B6 (mg/day) was significantly lower in anxious (1.93 ± 0.74 vs. 2.0 ± 0.74; P = 0.02) and depressed (1.86 ± 0.72 vs. 1.99 ± 0.74; P = 0.001) people than healthy participants. The lower level of vitamin B6 intake (tertile 1), after adjustment for the impacts of various confounding variables, in total population and women was associated with the higher odds of depression (OR = 1.41; 95% CI: 1.19, 2.31; P < 0.001. OR = 1.33; 95% CI: 1.08, 2. 21; P = 0.02, respectively). Also, the lower level of vitamin B6 intake (tertile 1) in total population and women was associated with the higher odds of anxiety (OR = 2.30; 95% CI: 1.31, 4.04; P < 0. 001, OR = 2.30; 95% CI: 1.19, 4.46; P = 0.04). Conclusion: The association of lower intakes vitamin B6 intake with increased risk of depression and anxiety was clearly supported by current study. A reasonable approach to tackle these disorders could be the improvement of nutritional status, accordingly large randomized controlled trials are suggested for providing more evidence.

scholarly journals Vitamin B6 Status among Vegetarians: Findings from a Population-Based Survey

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1627
Author(s):  
Paula Schorgg ◽  
Till Bärnighausen ◽  
Sabine Rohrmann ◽  
Aedin Cassidy ◽  
Nena Karavasiloglou ◽  
...  
Keyword(s):  
Vitamin B6 ◽  
High Performance ◽  
Geometric Mean ◽  
Population Based ◽  
Vegetarian Diet ◽  
Dietary Vitamin ◽  
Dietary Intakes ◽  
Linear Regression Models ◽  
Vitamin B6 Deficiency ◽  
Objectively Measured

Vitamin B6 from plant foods may have lower bioavailability than vitamin B6 from animal foods, but studies on objectively measured vitamin B6 status among vegetarians compared to non-vegetarians are lacking. Thus, the vitamin B6 status among vegetarians, but also pescatarians, and flexitarians, compared to meat-eaters was assessed in the population-based NHANES study (cycles 2007–2008 and 2009–2010). Data on serum pyridoxal-5′-phosphate (PLP) and 4-pyridoxic acid (4-PA) measured by high-performance liquid chromatography (HPLC) as well as dietary intakes from 24-h recalls were available for 8968 adults aged 20–80 years. Geometric mean (±standard error) PLP concentrations were 58.2 ± 6.0, 52.1 ± 3.7, 49.2 ± 4.6 and 51.0 ± 1.1 nmol/L among vegetarians, pescatarians, flexitarians, and meat-eaters. The 4-PA concentrations were 32.7 ± 4.0, 29.0 ± 2.5, 34.8 ± 5.6 and 33.0 ± 0.7, respectively. There were no statistically significant differences in PLP, 4-PA, and their ratio across the groups in multivariable linear regression models. Overall, the use of vitamin B6 supplements was the strongest predictor of the vitamin B6 status, followed by the dietary vitamin B6 intake. Interestingly, several other covariates were significantly associated with vitamin B6 biomarker levels, particularly serum albumin, creatinine and alkaline phosphatase, and should be considered when assessing the vitamin B6 status. In summary, our findings suggest that a vegetarian diet does not pose a risk for vitamin B6 deficiency.

Associations of dietary B vitamins intakes with depression in adults

2021 ◽  
Author(s):  
Yanjun Wu ◽  
Suyun Li ◽  
Weijing Wang ◽  
Dongfeng Zhang
Keyword(s):  
Vitamin B12 ◽  
Vitamin B6 ◽  
Vitamin B1 ◽  
B Vitamins ◽  
Dietary Vitamin ◽  
Dietary Intakes ◽  
Vitamin B2 ◽  
Logistic Regression Models ◽  
The People ◽  
The Impact

Abstract. Background: The impact of the dietary B vitamins intakes on the development of depression has been scarcely investigated. Thus, this study aimed to examine the associations of dietary B vitamins intakes with the risk of depression in American adults. Methods: The data we used in this study were from the National Health and Nutrition Examination Survey (NHANES) 2007-2014. We used the Logistic regression models to analyze the associations of the dietary intakes of B vitamins with the risk of depression. Results: 17,732 individuals (8,623 males and 9,109 females) were enrolled in the study and they were all 18 or older. Compared to the lowest quartile of dietary intake, the ORs (95%CIs) of the highest quartile were 0.64 (0.50–0.82), 0.78 (0.62–0.97), 0.60 (0.47–0.78), 0.65 (0.50–0.84), and 0.71 (0.54–0.95) for vitamin B1, vitamin B2, niacin, vitamin B6, and vitamin B12, respectively. Compared to the people whose dietary intakes below the RDA in the model 2, those with intake meeting the RDA of vitamin B1 (OR: 0.68; 95%CI: 0.56–0.84), niacin (OR: 0.65; 95%CI: 0.51–0.81), B6 (OR: 0.65; 95%CI: 0.52–0.81), or B12 (OR: 0.65; 95%CI: 0.48–0.88) had a lower risk of depression, severally. We also found a nonlinear negative association between dietary vitamin B1, vitamin B2, niacin, vitamin B6, and vitamin B12 intakes and the risk of depression in the dose-response analyses, severally. Conclusions: Our results suggested that dietary vitamin B1, vitamin B2, niacin, vitamin B6, and vitamin B12 intakes may be inversely associated with the risk of depression.

Vitamin B6 and Exercise

1994 ◽  
Vol 4 (2) ◽  
pp. 89-103 ◽  
Author(s):  
Melinda M. Manore
Keyword(s):  
Growth Hormone ◽  
Vitamin B6 ◽  
Low Energy ◽  
Dietary Vitamin ◽  
Dietary Intakes ◽  
Plasma Growth Hormone ◽  
Male Athletes

This paper presents an overview of vitaminand exercise, including the role that vitaminplays in gluconeogenesis and glycogenolysis and changes in vitaminmetabolism during exercise. The dietary vitaminintakes of athletes are also reviewed. Most studies report that male athletes have adequate dietary intakes of vitamin, whereas some females, especially those with low energy intakes, appear to have low vitaminintakes. Few studies have assessed the vitaminstatus of nonsupplementing athletes using the recommended status criteria. The role that vitaminmay play in attenuating the rise in plasma growth hormone observed during exercise is also reviewed. Finally, recomrnendations are given for further research in the area of vitaminand exercise.

Nutrition and the Physically Active Female

1992 ◽  
Vol 1 (1) ◽  
pp. 35-47
Author(s):  
Emily M. Haymes
Keyword(s):  
Iron Deficiency ◽  
Vitamin B6 ◽  
Physical Inactivity ◽  
Female Athletes ◽  
Primary Source ◽  
Adolescent Female ◽  
Dietary Intakes ◽  
Iron Intake ◽  
Physically Active ◽  
Factors Associated

Muscle glycogen is the primary source of energy during high intensity exercise. Increasing the carbohydrate content of the diet allows more glycogen to be stored. Some adolescent female athletes (gymnasts, dancers) do not consume adequate amounts of vitamin B6, folacin, and E. Many women have low dietary intakes of calcium and iron. Low calcium intake and physical inactivity are factors associated with the development of osteoporosis. Low iron intake is associated with the development of iron deficiency and anemia. Low ferritin levels (an index of body iron stores) are commonly observed in female athletes.

Membrane-associated microtubular areays induced in proximal myelinated processes of dorsal root ganglia by large doses of vitamin B6

1986 ◽  
Vol 44 ◽  
pp. 368-369
Author(s):  
V.J. Montpetit ◽  
S. Dancea ◽  
L. Tryphonas ◽  
D.F. Clapin
Keyword(s):  
Animal Model ◽  
Endoplasmic Reticulum ◽  
Dorsal Root Ganglia ◽  
Rough Endoplasmic Reticulum ◽  
Dorsal Root ◽  
Vitamin B6 ◽  
Morphological Changes ◽  
Model System ◽  
Sensory Nerves ◽  
Peripheral Sensory

Very large doses of pyridoxine (vitamin B6) are neurotoxic in humans, selectively affecting the peripheral sensory nerves. We have undertaken a study of the morphological and biochemical aspects of pyridoxine neurotoxicity in an animal model system. Early morphological changes in dorsal root ganglia (DRG) associated with pyridoxine megadoses include proliferation of neurofilaments, ribosomes, rough endoplasmic reticulum, and Golgi complexes. We present in this report evidence of the formation of unique aggregates of microtubules and membranes in the proximal processes of DRG which are induced by high levels of pyridoxine.

The Weight Loss Effects of Branched Chain Amino Acids and Vitamin B6: A Randomized Controlled Trial on Obese and Overweight Women

2018 ◽  
Vol 88 (1-2) ◽  
pp. 80-89 ◽  
Author(s):  
Zahra Shakibay Novin ◽  
Saeed Ghavamzadeh ◽  
Alireza Mehdizadeh
Keyword(s):  
Amino Acids ◽  
Weight Loss ◽  
Body Composition ◽  
Vitamin B6 ◽  
Controlled Trial ◽  
Density Lipoprotein ◽  
Branched Chain Amino Acids ◽  
Model Assessment ◽  
Waist To Hip Ratio ◽  
Branched Chain

Abstract. Branched chain amino acids (BCAA), with vitamin B6 have been reported to improve fat metabolism and muscle synthesis. We hypothesized that supplementation with BCAA and vitamin B6 would result in more weight loss and improve body composition and blood markers related to cardiovascular diseases. Our aim was to determine whether the mentioned supplementation would affect weight loss, body composition, and cardiovascular risk factors during weight loss intervention. To this end, we performed a placebo-controlled randomized clinical trial in 42 overweight and obese women (BMI = 25–34.9 kg/m2). Taking a four-week moderate deficit calorie diet (–500 kcal/day), participants were randomized to receive BCAA (6 g/day) with vitamin B6 (40 mg/day) or placebo. Body composition variables measured with the use of bioelectrical impedance analysis, homeostatic model assessment, and plasma insulin, Low density lipoprotein, High density lipoprotein, Total Cholesterol, Triglyceride, and fasting blood sugar were measured. The result indicated that, weight loss was not significantly affected by BCAA and vitamin B6 supplementation (–2.43 ± 1.02 kg) or placebo (–1.64 ± 1.48 kg). However, significant time × treatment interactions in waist to hip ratio (P = 0.005), left leg lean (P = 0.004) and right leg lean (P = 0.023) were observed. Overall, supplementation with BCAA and vitamin B6 could preserve legs lean and also attenuated waist to hip ratio.

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