scholarly journals Antimicrobial and insecticidal effects of essential oil and plant extracts of Myrcia oblongata DC in pathogenic bacteria and Alphitobius diaperinus

2022 ◽  
Vol 82 ◽  
Author(s):  
C. B. Santana ◽  
J. G. L. Souza ◽  
A. G. Toledo ◽  
L. F. A. Alves ◽  
D. S. Alves ◽  
...  
Keyword(s):  
Plant Extracts ◽  
Pathogenic Bacteria ◽  
Antioxidant Activities ◽  
Biological Activities ◽  
Adult Mortality ◽  
Chemical Diversity ◽  
Antioxidant Compounds ◽  
Alphitobius Diaperinus ◽  
Insecticidal Effect ◽  
Acetone Extracts

Abstract The secondary metabolism products of plants have influenced great economic interest, given their chemical diversity and biological activities. Because of this, this study evaluates the phytochemical composition, antimicrobial activity, insecticidal, and antioxidant activity of plant extracts and oil of Myrcia oblongata. Saponins, steroids, triterpenoids, tannins, and flavonoids were detected. The extracts showed antimicrobial capacity on the tested microorganisms, except for the methanolic extract, which showed no activity for P. mirabilis and S. enteritidis. Regarding the analysis of antioxidant compounds, the hexanic, ethyl acetate and acetone extracts showed higher antioxidant activities and also higher insecticidal performance on Alphitobius diaperinus larvae, resulting in 80% adult mortality. The results reported here show that there may be a relationship between antioxidant potential and the insecticidal effect of Myrcia oblongata DC. The components present in both the extract and the oil can be used as natural alternative to synthetic compounds in the biological control of parasites and pathogenic microorganisms.

scholarly journals Ameliorating effects of antioxidative compounds from four plant extracts in experimental models of diabetes

2013 ◽  
Vol 78 (3) ◽  
pp. 365-380 ◽  
Author(s):  
Svetlana Dinic ◽  
Aleksandra Uskokovic ◽  
Mirjana Mihailovic ◽  
Nevena Grdovic ◽  
Jelena Arambasic ◽  
...  
Keyword(s):  
Plant Extracts ◽  
Diabetes Management ◽  
Higher Plants ◽  
Antioxidant Activities ◽  
Castanea Sativa ◽  
Experimental Models ◽  
Antioxidant Defenses ◽  
Antioxidant Compounds ◽  
Important Place ◽  
Pancreatic Cell

Given that oxidative stress plays a major role in pancreatic ?-cell dysfunction and ultimate destruction, as well as in different complications of diabetes, therapy with antioxidants has assumed an important place in diabetes management. The relatively limited effects of established antioxidant compounds have stimulated efforts to develop new therapeutic strategies, e.g. to increase the endogenous antioxidant defenses through pharmacological modulation of key antioxidant enzymes. Plant extracts are gaining popularity in treating diabetes because many substances synthesized by higher plants and fungi possess antioxidant activities and can prevent or protect tissues against the damaging effects of free radicals. This review summarizes experimental models of diabetes and possible mechanisms that lie behind the antioxidative effects of ?-lipoic acid (LA), a powerful antioxidant and compound that stimulates cellular glucose uptake, as well as of plant extracts from sweet chestnut (Castanea sativa), edible mushroom (Lactarius deterrimus) and natural products containing ?-glucans in the treatment of diabetes. Their roles in preventing pancreatic ?-cell death and in ameliorating the effects of severe diabetic complications are discussed.

scholarly journals Endophytic Fungi from Terminalia Species: A Comprehensive Review

2019 ◽  
Vol 5 (2) ◽  
pp. 43 ◽  
Author(s):  
Rufin Marie Kouipou Toghueo ◽  
Fabrice Fekam Boyom
Keyword(s):  
Secondary Metabolites ◽  
Endophytic Fungi ◽  
Biological Activities ◽  
Fungal Endophytes ◽  
Structural Complexity ◽  
Chemical Diversity ◽  
Antioxidant Compounds ◽  
Comprehensive Review ◽  
Biological Potential ◽  
Insight Into

Endophytic fungi have proven their usefulness for drug discovery, as suggested by the structural complexity and chemical diversity of their secondary metabolites. The diversity and biological activities of endophytic fungi from the Terminalia species have been reported. Therefore, we set out to discuss the influence of seasons, locations, and even the plant species on the diversity of endophytic fungi, as well as their biological activities and secondary metabolites isolated from potent strains. Our investigation reveals that among the 200–250 Terminalia species reported, only thirteen species have been studied so far for their endophytic fungi content. Overall, more than 47 fungi genera have been reported from the Terminalia species, and metabolites produced by some of these fungi exhibited diverse biological activities including antimicrobial, antioxidant, antimalarial, anti-inflammatory, anti-hypercholesterolemic, anticancer, and biocontrol varieties. Moreover, more than 40 compounds with eighteen newly described secondary metabolites were reported; among these, metabolites are the well-known anticancer drugs, a group that includes taxol, antioxidant compounds, isopestacin, and pestacin. This summary of data illustrates the considerable diversity and biological potential of fungal endophytes of the Terminalia species and gives insight into important findings while paving the way for future investigations.

scholarly journals Polyphenol Rich Ajuga bracteosa Transgenic Regenerants Display Better Pharmacological Potential

Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 4874
Author(s):  
Samina Rubnawaz ◽  
Nosheen Akhtar ◽  
Rashid Mahmood ◽  
Asif Khan ◽  
Mohammad K. Okla ◽  
...  
Keyword(s):  
Plant Extracts ◽  
Antioxidant Activities ◽  
Biological Activities ◽  
Reducing Power ◽  
Rol Genes ◽  
Hydroxyl Ion ◽  
Total Antioxidant ◽  
Endangered Medicinal Herb

Ajuga bracteosa Wall. ex Benth. is an endangered medicinal herb traditionally used against different ailments. The present study aimed to create new insight into the fundamental mechanisms of genetic transformation and the biological activities of this plant. We transformed the A. bracteosa plant with rol genes of Agrobacterium rhizogenes and raised the regenerants from the hairy roots. These transgenic regenerants were screened for in vitro antioxidant activities, a range of in vivo assays, elemental analysis, polyphenol content, and different phytochemicals found through HPLC. Among 18 polyphenolic standards, kaempferol was most abundant in all transgenic lines. Furthermore, transgenic line 3 (ABRL3) showed maximum phenolics and flavonoids content among all tested plant extracts. ABRL3 also demonstrated the highest total antioxidant capacity (8.16 ± 1 μg AAE/mg), total reducing power, (6.60 ± 1.17 μg AAE/mg), DPPH activity (IC50 = 59.5 ± 0.8 μg/mL), hydroxyl ion scavenging (IC50 = 122.5 ± 0.90 μg/mL), and iron-chelating power (IC50 = 154.8 ± 2 μg/mL). Moreover, transformed plant extracts produced significant analgesic, anti-inflammatory, anticoagulant, and antidepressant activities in BALB/c mice models. In conclusion, transgenic regenerants of A. bracteosa pose better antioxidant and pharmacological properties under the effect of rol genes as compared to wild-type plants.

scholarly journals Insecticidal Effect of Ethnobotanical Plant Extracts Against Anopheles Arabiensis (Diptera: Culicidae) Under Laboratory Condition

2021 ◽  
Author(s):  
Desta Ejeta Fereda ◽  
Ansha Asme ◽  
Animut Asefa
Keyword(s):  
Larvicidal Activity ◽  
Malaria Vector ◽  
Plant Extracts ◽  
Anopheles Arabiensis ◽  
Methanol Extract ◽  
Mosquito Control ◽  
Larval Mortality ◽  
Ethanol Extract ◽  
Adult Mortality ◽  
Insecticidal Effect

Abstract Background: The emergence and spread of resistant strains of malaria vectors to chemical insecticides are becoming major problem for malaria vector management. Natural plant products play a vital role to resolve the current challenge of malaria control.Objective: The current study was conducted to evaluate insecticidal effect of ethnobotanical plant extracts against the primary malaria vector, Anopheles arabiensis in Northwestern Ethiopia.Methods: Primarily, ethnobotanical plants used for Anopheles mosquito control was surveyed in Dangur district, Northwestern Ethiopia. Insecticide susceptible strains of Anopheles arabiensis mosquito were reared in insectary of tropical and infectious diseases research center, Assosa university. The larvicidal and adulticidal potentials of frequently used plant extracts against susceptible strains of laboratory colony were evaluated.Result: A total of fifteen plants were identified as ethnobotanical plants helping the local people for mosquito control. Azadirachta indica, Ocimum lamiifolium, Ocimum americanum, Moringa olifiera leaf, and Moringa olifiera seed species of local plants were found to be frequently used to kill and/or repel mosquitoes in the study district. All the plant extracts were found to have potential larvicidal activity against 4th instar larvae of An. arabiensis and only ethanol and methanol extract of A. indica and O. lamiifolium were found to have potential adulticidal effect against adult of An. arabiensis. The highest larvicidal activity was observed in ethanol extract of A. indica with 95% larval mortality and lowest LC50 of 40.73 ppm and LC90 of 186.66 ppm. The highest adulticidal activity was observed in methanol extract of A. indica with 75% adult mortality at 300 ppm and lowest LC50 of 106.65ppm and LC90 of 1293ppm. The lowest larvicidal and adulticidal activity was observed in methanol extracts of O. lamiifolium with 63.35% larval mortality and leaf extract of M. olifiera with 50% adult mortality at 300 ppm, respectively.Conclusion: ethanol extract of A. indica exerted a remarkable larvicidal effect against An. arabiensis and thus it can be used for botanical mosquito insecticide development.

scholarly journals Suitability of Some Botanical Pesticides (Neem, Garlic and Red Chili) against Dry Fish Insects (Dermestes sp. Larvae and Necrobia sp. Adult)

2013 ◽  
Vol 21 (1-2) ◽  
pp. 93-103
Author(s):  
AAKM Nowsad ◽  
R Mondal ◽  
MN Hassan ◽  
MM Hossain ◽  
MR Islam
Keyword(s):  
Toxic Effect ◽  
Plant Extracts ◽  
Azadirachta Indica ◽  
Allium Sativum ◽  
Capsicum Frutescens ◽  
Botanical Pesticides ◽  
Insecticidal Effect ◽  
Acetone Extracts

Acetone extracts of red chili (Capsicum frutescens), garlic (Allium sativum) and neem (Azadirachta indica) were used to evaluate their insecticidal effects against a dry fish beetle, Dermestes sp. larvae and a mite, Necrobia sp. adult. The concentration of plant extracts were 60, 80 and 100% for Dermestes sp. larvae and 10, 15 and 20% for Necrobia sp. adult. The mortality of Necrobia sp. at 24, 48 and 72 hours after treatment (HAT) indicated that red chili extract possessed the highest insecticidal effect followed by neem and garlic. Mortality was found to be directly proportional to the concentration of plant extracts. For Necrobia sp. (adult) LC50 values of red chili, neem and garlic were 0.78, 0.85 and 1.68%, respectively at 24 HAT. Red chili was found to possess the highest insecticidal effect among these three with the highest toxic effect at 48 HAT (0.29%) and 72 HAT (0.03%). For the larvae of Dermestes sp., the LC50 values of red chili was 0.60%, neem 0.69% and garlic 1.15% at 24 HAT, again indicating that red chili had the highest insecticidal effect on dry fish insects.DOI: http://dx.doi.org/10.3329/pa.v21i1-2.16756 Progress. Agric. 21(1 & 2): 93 - 103, 2010

scholarly journals Insecticidal effect of ethnobotanical plant extracts against Anopheles arabiensis under laboratory conditions

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Desta Ejeta ◽  
Ansha Asme ◽  
Animut Asefa
Keyword(s):  
Malaria Vector ◽  
Plant Extracts ◽  
Azadirachta Indica ◽  
Anopheles Arabiensis ◽  
Methanol Extract ◽  
Mosquito Control ◽  
Larval Mortality ◽  
Ethanol Extract ◽  
Adult Mortality ◽  
Insecticidal Effect

Abstract Background The emergence and spread of resistant strains of malaria vectors to chemical insecticides are becoming major problems for malaria vector management. Natural plant products have a vital role to play in the current challenge of malaria control. The current study was conducted to evaluate insecticidal effect of ethnobotanical plant extracts against the primary malaria vector, Anopheles arabiensis in northwestern Ethiopia. Methods Primarily, ethnobotanical plants used for Anopheles mosquito control were surveyed in Dangur district, northwestern Ethiopia. Insecticide-susceptible strains of Anopheles arabiensis mosquito were reared in the insectary of the Tropical and Infectious Diseases Research Centre, Assosa University. After surveying plants used for mosquito control in local people, four frequently used plants were identified for extraction. The larvicidal and adulticidal potential of frequently used plant extracts against susceptible strains of the laboratory colony were evaluated. Results A total of 15 plants were identified as ethnobotanical plants that help local people with mosquito control. Azadirachta indica, Ocimum lamiifolium, Ocimum americanum, Moringa olifeira leaf, and Moringa olifeira seed species of local plants were found to be frequently used to kill and/or repel mosquitoes in the study district. All the plant extracts were found to have potential larvicidal activity against fourth instar larvae of An. arabiensis and only ethanol and methanol extract of Azadirachta indica and Ocimum lamiifolium were found to have potential adulticidal effect against adult of An. arabiensis. The highest larvicidal activity was observed in ethanol extract of Azadirachta indica with 95% larval mortality and lowest Lethal Concentration 50 (LC 50) of 40.73parts per million (ppm) and LC90 of 186.66 ppm. The highest adulticidal activity was observed in methanol extract of Azadirachta indica with 75% adult mortality at 300 ppm and lowest LC50 of 106.65 ppm and LC90 of 1,293 ppm. The lowest larvicidal and adulticidal activity was observed in methanol extracts of Ocimum lamiifolium with 63.35% larval mortality and leaf extract of Moringa olifeira with 50% adult mortality at 300 ppm, respectively. Conclusion Ethanol extract of Azadirachta indica exerted a remarkable larvicidal effect against An. arabiensis and thus it can be used for botanical mosquito insecticide development. Since the current finding is based on susceptible strain of An. arabiensis, further work on wild mosquitoes is recommended.

scholarly journals Antimicrobial and antioxidant activity of essential oil and different plant extracts of Psidium cattleianum Sabine

2016 ◽  
Vol 76 (1) ◽  
pp. 101-108 ◽  
Author(s):  
M. C. Scur ◽  
F. G. S. Pinto ◽  
J. A. Pandini ◽  
W. F. Costa ◽  
C. W. Leite ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Antioxidant Activity ◽  
Essential Oil ◽  
Plant Extracts ◽  
Antioxidant Activities ◽  
Biological Activities ◽  
Ethanolic Extract ◽  
Phytochemical Screening ◽  
Psidium Cattleianum ◽  
Ethanolic Extracts

Abstract The goals of the study were to determinethe antimicrobial and antioxidant activities of essential oil and plant extracts aqueous and ethanolic of Psidium cattleianum Sabine; the chemical composition of the essential oil of P. cattleianum; and the phytochemical screening of aqueous and ethanolic extracts of the same plant. Regarding the antimicrobial activity, the ethanolic extract exhibited moderate antimicrobial activity with respect to bacteria K. pneumoniae and S. epidermidis, whereas, regarding other microorganisms, it showed activity considered weak. The aqueous extract and the essential oil showed activity considered weak, although they inhibited the growth of microorganisms. About the antioxidant potential, the ethanolic and aqueous extracts exhibited a scavenging index exceeding 90%, while the essential oil didn´t show significant antioxidant activity. Regarding the phytochemical composition, the largest class of volatile compounds identified in the essential oil of P. cattleianum included the following terpenic hydrocarbons: α-copaene (22%); eucalyptol (15%), δ-cadinene (9.63%) and α-selinene (6.5%). The phytochemical screening of extracts showed the presence of tannins, flavonoids, and triterpenoids for aqueous and ethanolic extracts. The extracts and essential oils inhibit the growth of microrganisms and plant extracts showed significant antioxidant activity. Also, the phytochemical characterization of the essential oil showed the presence of compounds interest commercial, as well as extracts showed the presence of important classes and compounds with biological activities.

scholarly journals BIOLOGICAL ACTIVITIES OF GARCINIA MANGOSTANA

2017 ◽  
Vol 10 (9) ◽  
pp. 272 ◽  
Author(s):  
Jebalsy Lalitha ◽  
Prince Clarance P ◽  
Jerin Sales T ◽  
Mary Archana A ◽  
Agastian P
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Ethyl Acetate ◽  
Antioxidant Activities ◽  
Biological Activities ◽  
Gas Chromatography Mass Spectrometry ◽  
Antioxidant Compounds ◽  
Phytochemical Analysis ◽  
Garcinia Mangostana

  Objective: The aim of the present study was to investigate in vitro antibacterial, antifungal, and antioxidant activities of different solvent extracts of Garcinia mangostana leaves.Methods: The powdered leaf was subjected to sequential extraction using hexane, ethyl acetate (EA), and methanol. The extracts were subjected to quantitative and qualitative phytochemical analysis, antimicrobial, and antioxidant activities. The best solvent extract was subjected to gas chromatography–mass spectrometry (GC-MS) analysis.Results: The highest activity was recorded in EA extract which was subjected to GC-MS analysis revealing the presence of squalene (17.09%).Conclusion: From this present study, we conclude that EA is the best solvent for extracting antimicrobial and antioxidant compounds from the leaves of G. mangostana.

scholarly journals Antibacterial and antioxidant potential of ethyl acetate extract from Streptomyces AIA12 and AIA17 isolated from gut of Chanos chanos

2021 ◽  
Vol 22 (8) ◽  
Author(s):  
Muhammad Alfid Kurnianto ◽  
Harsi Dewantari Kusumaningrum ◽  
Hanifah Nuryani Lioe ◽  
Ekowati Chasanah
Keyword(s):  
Ethyl Acetate ◽  
Crude Extract ◽  
Ethyl Acetate Extract ◽  
Antioxidant Activities ◽  
Biological Activities ◽  
Antioxidant Potential ◽  
Antioxidant Compounds ◽  
Malt Extract ◽  
Chanos Chanos ◽  
Dpph Scavenging

Abstract. Kurnianto MA, Kusumaningrum HD, Lioe HN, Chasanah E. 2021. Antibacterial and antioxidant potential of ethyl acetate extract from Streptomyces AIA12 and AIA17 isolated from gut of Chanos chanos. Biodiversitas 22: 3196-3206. Streptomyces has been recognized as a promising and productive source of antibacterial and antioxidant compounds. The phenotypic and genomic characterizations indicated AIA12 and AIA17 are closely related to the S. globisporus ARGB01 and S. misionensis S1-SC15, respectively. Incubation on yeast-malt extract broth for nine days (AIA12) and 11 days (AIA17) proved to be the best growth medium and optimum antibacterial production time for these two strains. Crude-extract of extracellular secondary metabolites, obtained by ethyl acetate extraction, demonstrated broad-spectrum inhibitory activity against Pseudomonas aeruginosa InaCC B52, Staphylococcus aureus ATCC 25923, Bacillus cereus ATCC 10876, Escherichia coli ATCC 25922, Salmonella Typhimurium ATCC 14028, and Listeria monocytogenes with minimum inhibitory and minimum bactericidal concentrations from 2.5 to 0.31 and 5.0 to 0.31 mg mL-1, respectively. Evaluation of antioxidant showed AIA17 crude-extract had moderate DPPH scavenging and antioxidant activities of 65.122% ± 0.56 and 28.178 ± 0.24 mg ascorbic acid equivalent antioxidant capacity (AEAC g-1), respectively. The identification of compounds through profiling with RP-HPLC showed optimum absorbance at 210 and 214 nm, which showed the presence of peptide groups in the constituent compounds' molecular structure. These findings indicate that Chanos chanos-derived Streptomyces produces valuable bioactive compounds with various promising biological activities.

scholarly journals Insecticidal Effect of Ethnobotanical Plant Extracts Against Anopheles Arabiensis (Diptera: Culicidae) Under Laboratory Condition

2021 ◽  
Author(s):  
Desta Ejeta Fereda ◽  
Ansha Asme ◽  
Animut Asefa
Keyword(s):  
Larvicidal Activity ◽  
Malaria Vector ◽  
Plant Extracts ◽  
Anopheles Arabiensis ◽  
Methanol Extract ◽  
Mosquito Control ◽  
Larval Mortality ◽  
Ethanol Extract ◽  
Adult Mortality ◽  
Insecticidal Effect

Abstract BackgroundThe emergence and spread of resistant strains of malaria vectors to chemical insecticides are becoming major problem for malaria vector management. Natural plant products play a vital role to resolve the current challenge of malaria control. ObjectiveThe current study was conducted to evaluate insecticidal effect of ethnobotanical plant extracts against the primary malaria vector, Anopheles arabiensis in Northwestern Ethiopia. MethodsPrimarily, ethnobotanical plants used for Anopheles mosquito control was surveyed in Dangur district, Northwestern Ethiopia. Insecticide susceptible strains of Anopheles arabiensis mosquito were reared in insectary of tropical and infectious diseases research center, Assosa university. The larvicidal and adulticidal potentials of frequently used plant extracts against susceptible strains of laboratory colony were evaluated. ResultA total of fifteen plants were identified as ethnobotanical plants helping the local people for mosquito control. Azadirachta indica, Ocimum lamiifolium, Ocimum americanum, Moringa olifiera leaf, and Moringa olifiera seed species of local plants were found to be frequently used to kill and/or repel mosquitoes in the study district. All the plant extracts were found to have potential larvicidal activity against 4th instar larvae of An. arabiensis and only ethanol and methanol extract of A. indica and O. lamiifolium were found to have potential adulticidal effect against adult of An. arabiensis. The highest larvicidal activity was observed in ethanol extract of A. indica with 95% larval mortality and lowest LC50 of 40.73 ppm and LC90 of 186.66 ppm. The highest adulticidal activity was observed in methanol extract of A. indica with 75% adult mortality at 300 ppm and lowest LC50 of 106.65ppm and LC90 of 1293ppm. The lowest larvicidal and adulticidal activity was observed in methanol extracts of O. lamiifolium with 63.35% larval mortality and leaf extract of M. olifiera with 50% adult mortality at 300 ppm, respectively. Conclusionethanol extract of A. indica exerted a remarkable larvicidal effect against An. arabiensis and thus it can be used for botanical mosquito insecticide development.

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