scholarly journals Caracterização química e atividades antioxidante e antifúngica do óleo essencial das flores de [Cochlospermum regium (Mart. ex Schrank.) Pilger] (Bixaceae)

2020 ◽  
Vol 1 (52) ◽  
pp. 80
Author(s):  
Antonio Carlos Pereira de Menezes Filho ◽  
Wendel Cruvinel De Sousa ◽  
Carlos Frederico De Souza Castro
Keyword(s):  
Antioxidant Activity ◽  
Refractive Index ◽  
Antifungal Activity ◽  
Essential Oil ◽  
High Efficiency ◽  
Optical Rotation ◽  
Antioxidant Agent ◽  
Agricultural Use ◽  
Liquid Yield ◽  
Organoleptic Parameters

<p class="Normal1">The objective of this work was to characterize the chemical and physicochemical profile, and the antioxidant and antifungal activities of the essential oil from Cochlospermum regium flowers. The flowers were collected in a riparian Cerrado area. The essential oil was extracted by hidrodestilation in Clevenger. The organoleptic parameters were evalueted for (color, visual and aroma), for physicochemical, yield (%), solubility, optical rotation (αD ), refractive index (20 °C) and density (25 °C g mL-1), antioxidant activity were determined by the reduction of free radical DPPH, and the antifungal activity was determined through the percentage of growth inhibition on Sclerotinia sclerotiorum, Colletotrichum gloeosporioides and Aspergillus flavus. The essential oil from C. regium flowers had an oily, clear, crystalline and strongly aromatic liquid, yield of 0.099%, positive solubility, optical rotation +36.1 αD , refractive index 1.3297 20 °C, relative density of 0.933 g mL-1. The chemical profile showed the following major compounds ocimene&lt;(E)-β-&gt; with 15.87%, caryophyllene E 11.53%, γ-muurolene 20.07%, bicyclogermacrene 16.11% and, rosifoliol with 31.09%. The antioxidant activity showed high efficiency in reducing of the DPPH radical in all concentrations varied between 50 to 0.031 mg mL -1 between 95.25% to 40.09%. The antifungal activity showed 100% of mycelial inhibition in 100 and 50 µL mL-1 concentrations for S. sclerotinia, C. gloeosporioides and A. flavus. In the lowest concentration of 1.56 µL mL-1 inhibition was also observed for S. sclerotiorum and A. flavus and for 3.13 µL mL-1 for C. gloeosporioides with 26.12; 6.08 and 10.07%, respectively. The essential oil of the flowers from C. regium proved to be an efficient natural product for the development of medicines, as an antioxidant agent and, antifungal for agricultural use.</p>

scholarly journals Chemical profile and antioxidant, antibacterial, and cytotoxic activities on Artemia salina from the essential oil of leaves and xylopodium of Cochlospermum regium

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Roberta Heloísa de Paula Magalhães ◽  
Antonio Carlos Pereira de Menezes Filho ◽  
Matheus Vinicius Abadia Ventura ◽  
Hellen Regina Fernandes Batista-Ventura ◽  
Carlos Frederico de Souza Castro ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Refractive Index ◽  
Essential Oil ◽  
Relative Density ◽  
Optical Rotation ◽  
Artemia Salina ◽  
Cytotoxic Activities ◽  
Chemical Profile ◽  
Radical Reduction ◽  
Antibacterial Potential

Cochlospermum regium is a shrub plant species from the Cerrado domain used in traditional medicine. This study aimed to evaluate the chemical profile and antioxidant, antibacterial and cytotoxic activities on Artemia salina from the essential oil of fresh leaves and xylopodium. Fresch leaves and xylopodium of C. regium were collected in an area of ​​Cerrado domain in Goiás State, Brazil, 2021. The essential oil was obtained by hydrodistillation, the yield was quantified and the chemical profile determined by gas chromatography with mass spectrometry (GC-MS). Physicochemical analyzes were carried out for organoleptic analysis (color and appearance), solubility, relative density (g mL-1), refractive index, optical rotation (αD), antioxidant activity in DPPH radical reduction (IC50 µL mL-1), antibacterial activity on Escherichia coli, Staphylococcus aureus, Enterococcus faecalis, Salmonella serovar Enteritidis and Salmonella serovar Thyphymurium by the disc method (mm), and cytotoxicity bioassay on Artemia salina (LC50 µg mL-1). The major compounds for the essential oil of fresh leaves were viridiflorol 10.21%, Copaen-4-α-ol <β>, longiborneol 9.07 and β-bisabolene 11.48%, and for the essential oil of xylopodium β-selinene 26.17%, aromadendrene 8.66 % and thujopsene 8.09%. The yield was 0.58 and 0.33%, color slightly yellow and yellow for fresh leaves and xylopodium, respectively. Positive solubility, refractive index of 1.3468 and 1.3347, optical rotation +48.8 and +21.5, relative density 0.932 and 0.936 g mL-1, antioxidant activity IC50 = 47.65 and 111.16 µL mL-1 for fresh leaves essential oil and xylopodium, respectively. The essential oil from fresh leaves showed high antibacterial potential for all strains, as well as for cytotoxic activity on A. salina with LC50 = 90.17 and 625.08 µg mL-1, respectively.

The Citrus reticulata essential oil: evaluation of antifungal activity against penicillium species related to bakery products spoilage

10.5219/1695 ◽  
2021 ◽  
Vol 15 ◽  
pp. 1112-1119
Author(s):  
Hana Ďúranová ◽  
Veronika Valková ◽  
Lucia Galovičová ◽  
Jana Štefániková ◽  
Miroslava Kačániová
Keyword(s):  
Antioxidant Activity ◽  
Antifungal Activity ◽  
Essential Oil ◽  
Vapor Phase ◽  
Radical Scavenging ◽  
Diffusion Method ◽  
Wheat Bread ◽  
Citrus Reticulata ◽  
Disc Diffusion ◽  
Disc Diffusion Method

Fungal food spoilage plays a key role in the deterioration of food products, and finding a suitable natural preservative can solve this problem. Therefore, antifungal activity of green mandarin (Citrus reticulata) essential oil (GMEO) in the vapor phase against the growth of Penicillium (P.) expansum and P. chrysogenum inoculated on wheat bread (in situ experiment) was investigated in the current research. The volatile compounds of the GMEO were analyzed by a gas chromatograph coupled to a mass spectrometer (GC–MS), and its antioxidant activity was determined by testing free radical-scavenging capacity (DPPH assay). Moreover, the disc diffusion method was used to analyze the antifungal activity of GMEO in in vitro conditions. The results demonstrate that the Citrus reticulata EO consisted of α-limonene as the most abundant component (71.5%), followed by γ-terpinene (13.9%), and β-pinene (3.5%), and it displayed the weak antioxidant activity with the value of inhibition 5.6 ±0.7%, which corresponds to 103.0 ±6.4 µg TEAC.mL-1. The findings from the GMEO antifungal activity determination revealed that values for the inhibition zone with disc diffusion method ranged from 0.00 ±0.00 (no antifungal effectiveness) to 5.67 ±0.58 mm (moderate antifungal activity). Finally, exposure of Penicillium strains growing on bread to GMEO in vapor phase led to the finding that 250 μL.L-1 of GMEO exhibited the lowest value for mycelial growth inhibition (MGI) of P. expansum (-51.37 ±3.01%) whose negative value reflects even supportive effect of the EO on the microscopic fungus growth. On the other hand, GMEO at this concentration (250 μL.L-1) resulted in the strongest inhibitory action (MGI: 54.15 ±1.15%) against growth of P. chrysogenum. Based on the findings it can be concluded that GMEO in the vapor phase is not an effective antifungal agent against the growth of P. expansum inoculated on bread; however, its antifungal potential manifested against P. chrysogenum suggests GMEO to be an appropriate alternative to the use of chemical inhibitors for bread preservation.

scholarly journals An in Vitro Study on Antifungal Properties, Total Polyphenolic Content and Antioxidant Activity of Different Parts of Selected Fruit Trees

2020 ◽  
Vol 71 (4) ◽  
pp. 355-363
Author(s):  
Derya Ustaömer ◽  
Elif Topaloğlu ◽  
Bilge Yilmaz ◽  
Hüseyin Serencam ◽  
İlhan Deniz
Keyword(s):  
Antioxidant Activity ◽  
Antifungal Activity ◽  
Essential Oil ◽  
Water Extract ◽  
Fruit Trees ◽  
Hot Water ◽  
Methanol Extracts ◽  
Hot Water Extract ◽  
Polyphenolic Content ◽  
Total Polyphenolic Content

The purpose of this study was to investigate the antifungal properties, total polyphenolic content and antioxidant activity of sapwood, heartwood and bark parts obtained from three different fruit trees; olive (Olea europaea L.), loquat (Eriobotrya japonica Lindl.) and date plum (Diospyros lotus L.) grown in Turkey. Firstly, the hydrodistillation products (essential oil, hydrosol, hot-water extract) were acquired from these parts of selected trees, and methanol and ethanol extracts of the same samples were also prepared for the analysis. The antifungal activities of essential oil, hydrosol, hot-water extract, ethanol and methanol extracts were determined against wood-rot fungus Coniophora puteana. In addition, polyphenol contents and antioxidant activities of ethanol and methanol extracts were investigated. According to the results, generally, the essential oil of the parts of three fruit trees was found to inhibit the fungal growth. All hot water extracts and hydrosols of these trees showed no antifungal activity against C. puteana. It was found that olive tree had higher antifungal activity than loquat and date plum trees. The methanol extract of loquat bark gave the highest total phenolic content, total flavonoid content and condensed tannin content compared to parts of the other trees. Furthermore, the highest total polyphenol content and antioxidant activity among three fruit trees were determined in ethanol and methanol extracts of the bark and heartwood of loquat tree. Based on these findings, it can be concluded that the parts of studied fruit trees have less or more antifungal and antioxidant activity depending on the experimental parameters, and therefore they can be evaluated as alternative natural antifungal and antioxidant sources.

scholarly journals Chromatographic analysis and physicochemical evaluation of the essential oil of Bauhinia monandra Kurz flowers

2020 ◽  
Vol 9 (8) ◽  
pp. e454985979
Author(s):  
Antonio Carlos Pereira de Menezes Filho ◽  
Luciene Teixeira Gonçalves Romão ◽  
Eloisa Borges dos Reis ◽  
Karla da Silva Malaquias ◽  
Carlos Frederico de Souza Castro ◽  
...  
Keyword(s):  
Essential Oil ◽  
High Efficiency ◽  
Optical Rotation ◽  
Chemical Profile ◽  
Postgraduate Students ◽  
Retention Factors ◽  
Modern Technique ◽  
Physicochemical Evaluation ◽  
Tlc Analysis ◽  
Layer Chromatography

The study of chromatographic techniques, classical and modern, describes the simplicity and, at the same time, the advances that this area has undergone in recent years in quality scientific research and also in learning in undergraduate and postgraduate courses around the world. This paper investigate a characterization by thin layer chromatography (TLC) and gas chromatography coupled with mass spectrometry (GC-MS), as a method developed by graduate students that involve a combination of a classic and modern technique, as well as results about the physicochemical properties of the essential oil of Bauhinia monandra flower. Essential oil was extracted by Clevenger, the TLC was performed in different eluents and developers, and thus the retention factors (Rfs), and the chemical profile by GC-MS were obtained. The essential oil of the flowers showed a yield of 0.06%, positive solubility in ethanol 70%, refractive index of 1.3621, optical rotation of +36.4αD and relative density of 0.941 g mL-1 at 20 °C. In the TLC analysis 18 Rfs were observed after the use of different developers, with the predominant class of oxygenates compounds. In the GC-MS analysis, 7 compounds were observed, being two majorities, characterized as panaxene with 20.51% and the α-guaiene with 33.39%. The essential oil of B. monandra flower showed a predominance of 70.22% of sesquiterpenic compounds. The allied techniques, classic and modern, demonstrated different ways of evaluating the essential oil through its chemical composition, both techniques showed high efficiency and precision, in addition was an appropriate project developed by postgraduate students.

scholarly journals Phytochemical characterization, antioxidant and antibacterial activity of essential oil and extracts of Tagetes patula on Staphylococcus aureus

2020 ◽  
Vol 37 (4) ◽  
pp. 347-367
Author(s):  
Virginia Monserrate López Zambrano ◽  
Alex Alberto Dueñas Rivadeneira ◽  
José Gerardo Cuenca Nevárez ◽  
Joan Manuel Rodríguez-Díaz
Keyword(s):  
Staphylococcus Aureus ◽  
Antioxidant Activity ◽  
Refractive Index ◽  
Antibacterial Activity ◽  
Minimum Inhibitory Concentration ◽  
Essential Oil ◽  
Inhibitory Concentration ◽  
In Vitro Tests ◽  
Tagetes Patula

Tagetes patula is an ornamental plant species and its essential oils contain potentially allelopathic active ingredients. The objective of the present study was to evaluate the phytochemical composition of extracts, the antioxidant and antibacterial activity of the essential oil of flowering leaves of the species, on Staphylococcus aureus. For this, the extraction of the essential oil by hydrodistillation was carried out, evaluating the physical characteristics (solubility, density and refractive index) and phytochemical characteristics of the extracts through a phytochemical screening (alkaloids, flavonoids, phenols, saponins, tannins and reducing sugars). The quantificatics of phenols in the essential oil was performed by the Folin Ciocalteu method, the antioxidant activity using the DPPH and ABTS tests, the antimicrobial activity by determining the minimum inhibitory concentration. The results obtained showed for the essential oil, a density of 0,733 g.mL-1, refractive index of 1,47 and insolubility in ethanol (70 %), presence of tannins, flavonoids and phenols in the extracts. The phenolic content was 1.024 ± 0,19 mg.g-1 TAE, the antioxidant activity with DPPH was 87,6 ± 0,18 µmol.g-1TE and with ABTS 180,83 ± 0,36 µmol.g-1 TE in Trolox equivalent. The minimum inhibitory concentration was 16,67 mm against S. aureus, in response to which it is concluded that the essential oil of T. patula had antioxidant activity against radicals DPPH and ABTS, high phenolic contents and showed antibacterial activity in vitro tests against S. aureus.

scholarly journals EFEK AROMATERAPI MINYAK ATSIRI MAWAR (Rosa damascena MILL.) DAN KULIT JERUK LIMAU (Citrus amblycarpa) TERHADAP JUMLAH MIKROBA UDARA RUANGAN BERPENDINGIN

2020 ◽  
Vol 19 (2) ◽  
Author(s):  
Oom Komala ◽  
Novi Fajar Utami ◽  
Siti Mariyam Rosdiana
Keyword(s):  
Refractive Index ◽  
Essential Oil ◽  
Optical Rotation ◽  
Acid Number ◽  
National Standard ◽  
Plate Count ◽  
Rosa Damascena ◽  
Specific Level ◽  
Energy Material ◽  
Plate Count Method

Energy, material, and or other components were entered to the air by activities of human could cause air quality down to a specific level that could affect human health. The bacteria in the human oral cavity such as Staphylococcus sp. were found in the air during common activities such as coughing, sneezing, and speaking. The research aimed to assess the influence of the combination of oils essential of Rosa damacena and leather oil of Citrus amblycarpa against a decline in the total of microbes on air-conditioned rooms. The method of the research  was used the evaporation of aromatherapy and plate count method. The results were showed that P3 with the concentration of oils essential of R. damacena 2% and leather oil of C. amblycarpa 5% most effective could decrease the total of microbes with an average of 72.5%. Organoleptic, relative density, refractive index, solubility in 90% ethanol, and acid number analysis of Rosa damacena and Citrus amblycarpa leather essential oils met the Indonesian National Standard requirements except for the acid number of leatherlime essential oil and the optical rotation of rose essential oil. It is concluded that the combination of oils essential R. damacena and leather oil of C. amblycarpa  could reduce the total of microbes on air-conditioned rooms.

scholarly journals AKTIVITAS ANTIMIKROBA MINYAK ESENSIAL JAHE MERAH (Zingiber officinale var. Rubrum) DAN LENGKUAS MERAH (Alpinia purpurata K. Schum) TERHADAP BAKTERI PATOGEN DAN PERUSAK PANGAN

2015 ◽  
Vol 35 (01) ◽  
pp. 43 ◽  
Author(s):  
Tita Rialita ◽  
Winiati Pudji Rahayu ◽  
Lilis Nuraida ◽  
Budi Nurtama
Keyword(s):  
Antimicrobial Activity ◽  
Refractive Index ◽  
Essential Oil ◽  
Essential Oils ◽  
Optical Rotation ◽  
Acid Number ◽  
Food Spoilage ◽  
E Coli ◽  
Spoilage Bacteria ◽  
Red Ginger

The aims of this study was to determine the characteristics, composition and antimicrobial activity of essential oils of local Indonesian red ginger and red galangal against four pathogenic and food spoilage bacteria, which were B.cereus ATCC 10876, E. coli ATCC 25922, S. typhimuriumATCC 14028, and P. aeruginosa ATCC 27853. Analysis of physicochemical characteristics was carried outin accordance with ISO7355:1985. The chemical compositionwas analyzed using aGC-MS. The antimicrobial activity was determined by disc diffusion method and broth microdillution method was used for determine MIC and MBC values. Red ginger essential oil characteristic was brownish yellow, specific gravity 0.883, refractive index 1.480, optical rotation -8.45o, clear soluble (1:1) in 90 % alcohol, 2.06 acid number and 42.45 ester number. Redgalangal essential oil had a characteristic bright yellow color, specific gravity 0.895, refractive index 1.496, optical rotation -9.15o, clear soluble (1:1) in 90 % alcohol, 1.95 acid number and 140.15 ester number. The major component of red ginger essential oils were trimethyl-heptadien-ol, ar-curcumene, camphene, carbaldehyde, -sesquiphellandrene, and nerol; while the major component of red galangal essential oil were 1.8-cineole, chavicol, 9-desoxo-9-xi-hydroxy-3-pentaacetate-3,5,7,8,9,12-Ingol,- caryophyllene and -selinene. The essential oil of red ginger and red galangal hadmoderate antibacterial activity against pathogenic and food spoilage bacteria with the average inhibition zone 7.17-10.33 and 7.25-11.17mm.Red ginger essential oils could inhibit the growth of tested bacteria with MIC values of 2.65-3.97 mg/mL and MBC value of 3.10-5.29 mg/mL, while the red galangal essential oil could inhibit the growth of tested bacteria with MIC values of 1.79-4.03 mg mL and MBC values of 1.79-4.92 mg/mL. Based on the MIC and MBC values,all tested bacteriasensitivity to essential oils of red ginger and galangal red decline in a row B.cereus > E. coli > S. typhimurium> P. aeruginosa. Sensitivity of Gram positive and Gram negative bacteria to both essential oils demonstrate the potential of the oils to be used as a natural preservative in the food industry.Keywords: Antimicrobial, essential oil, red ginger, red galangal ABSTRAKPenelitian ini bertujuan untuk mengetahui karakteristik, komposisi dan aktivitas antimikroba minyak esensial jahe merah dan lengkuas merah lokal Indonesia terhadap empat spesies bakteri patogen dan perusak pangan, yaitu B.cereus ATCC 10876, E.coli ATCC 25922, S. typhimurium ATCC 14028, dan P. aeruginosa ATCC 27853. Analisis karakteristikfisika-kimia dilakukan sesuai standar ISO 7355:1985. Komposisi kimia dianalisis menggunakan alat GC-MS. Pengujian aktivitas antimikroba dilakukan dengan metode difusi cakram untuk menentukan zona hambat, sertabroth microdillution untuk menentukan nilai Minimum Inhibitory Concentration (MIC) dan Minimum Bactericidal Concentration (MBC).Karakteristik minyak esensial jahe merah yang dihasilkan yaitu kuning kecoklatan, berat jenis 0,883, indeks bias 1,480, putaran optik -8.45, larut jernih (1:1) dalam alkohol 90%, bilangan asam 2,06, dan bilangan ester 42,45. Minyak esensial lengkuas merah memiliki karakteristik warna kuning terang, berat jenis 0,895, indeks bias 1,496, putaran optik-9.15, larut jernih (1:1) dalam alkohol 90%, bilangan asam 1,95 dan bilangan ester 140,15. Komponen mayor minyak esensial jahe merah terdiri dari trimethyl-heptadien-ol, ar-curcumene, camphene, carbaldehyde, -sesquiphellandrene, dan nerol; sedangkan komponen mayor minyak esensial lengkuas merah terdiri dari 1.8-cineole, chavicol,9-desoxo9-xi-hydroxy-3,5,7,8,9,12-pentaacetat-ingol, -caryophyllenedan -selinene. Minyak esensial jahe merah dan lengkuas merah memiliki aktivitas antibakteri yang bersifat moderat terhadap bakteri patogen dan perusak pangan, dengan kisaran zona hambat rata-rata 7,17-10,33 mm dan 7,25-11,17 mm. Minyak esensial jahe merah dapat menghambatpertumbuhan bakteri uji pada nilai MIC 2,65-3,97 mg/mL dan nilai MBC 3,10-5,29 mg/mL, sedangkan minyak esensial lengkuas merah dapat menghambat bakteri uji dengan nilai MIC 1,79-4,03 mg/mL dan nilai MBC 1,79-4,92 mg/mL. Berdasarkan nilai MIC dan MBC, sensitivitas bakteri uji terhadap minyak esensial jahe merah dan lengkuas merah menurun berturut-turut dari B. cereus > E. coli > S. typhimurium > P. aeruginosa. Sensitivitas bakteri Gram positif dan Gram negatif terhadap kedua minyak esensial ini menunjukkan potensi minyak esensial jahe merah dan lengkuas merah untuk digunakan sebagai pengawet alami di industri pangan.Kata kunci: Antimikroba, jahe merah, lengkuas merah, minyak esensial

scholarly journals Quality Assessment of the Essential Oil from Eucalyptus globulus Labill of Blida (Algeria) Origin

2014 ◽  
Vol 36 ◽  
pp. 303-315 ◽  
Author(s):  
Mohamed Nadjib Boukhatem ◽  
Mohamed Amine Ferhat ◽  
Abdelkrim Kameli ◽  
Fairouz Saidi ◽  
Kerkadi Walid ◽  
...  
Keyword(s):  
Refractive Index ◽  
Essential Oil ◽  
Specific Gravity ◽  
Eucalyptus Globulus ◽  
Optical Rotation ◽  
Chemical Constituents ◽  
Chemical Properties ◽  
Acid Number ◽  
Gas Chromatography Mass Spectrometry ◽  
Chemical Components

Despite the reputation earned by aromatic and medicinal plants of Algeria, the chemical constituents of Eucalyptus globulus essential oil (EGEO) of Blida origin has not previously been investigated. Thus, the present study has been conducted for the determination of chemical constituents and different physico-chemical properties of the EGEO. Chemical composition of the EGEO, grown in Algeria, was analysed by Gas Chromatography-Mass Spectrometry. The chemical components were identified on the basis of Retention Time and comparing with mass spectral database of standard compounds. Relative amounts of detected compounds were calculated on the basis of GC peak areas. Fresh leaves of E. globulus on steam distillation yielded 0.96 % (v/w) of essential oil whereas the analysis resulted in the identification of a total of 11 constituents, 1.8 cineole (85.8 %), α-pinene (7.2 %), and β-myrcene (1.5 %) being the main components. Other notable compounds identified in the oil were β-pinene, limonene, α-phellandrene, γ-terpinene, linalool, pinocarveol, terpinen-4-ol, and α-terpineol. The physical properties such as specific gravity, refractive index and optical rotation and the chemical properties such as saponification value, acid number and iodine number of the EGEO were examined. The oil extracted has been analyzed to have 1.4602 - 1.4623 refractive index value, 0.918 - 0.919 specific gravity (sp.gr.), +9 - +10 optical rotation that satisfy the standards stipulated by European Pharmacopeia. All the physical and chemical parameters were in the range indicated by the ISO standards. Our findings will help to access the quality of the Eucalyptus oil which is important in the production of high value essential oils that will help to improve the economic condition of the community as well as the nation.

scholarly journals Etude De Quelques Proprietes Biologiques De Ocimum Gratissimum L., Une Lamiaceae Recoltee A Daloa (Côte d'Ivoire)

2018 ◽  
Vol 14 (3) ◽  
pp. 477
Author(s):  
Elisée Kporou Kouassi ◽  
Sitapha Ouattara ◽  
Cendrine Seguin ◽  
Sylvie Fournel ◽  
Benoit Frisch
Keyword(s):  
Antioxidant Activity ◽  
Antifungal Activity ◽  
Antitumor Activity ◽  
Essential Oil ◽  
Cytotoxic Activity ◽  
Colorimetric Assay ◽  
Biological Properties ◽  
Test Results ◽  
Ocimum Gratissimum ◽  
T Lymphoma

Introduction: Ocimum gratissimum is used in traditional Ivorian medicine for its multiple therapeutic virtues. Scope: Evaluate the biological properties of the essential oil of this plant. Methods: Antitumor activity was assessed using the MTS colorimetric assay on six (06) cell lines, the antifungal activity was evaluated by double dilution slant method on four (04) strains of clinical fungi, the potential antioxidant was determined by the DPPH test. Results: The strongest cytotoxic activity was obtained on Jurkat (T lymphoma) with an IC50 = 80 μg / ml. The best antifungal activity was observed on C. albicans with MIC and FMC values obtained at 12.5 μg / ml. Antioxidant activity was evaluated at F = 187 ± 1.57 mM Trolox / ml or (I = 38 ± 0.74%). Conclusion: The essential oil has interesting biological properties like as cytotoxic, antifungal and antioxidant

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