scholarly journals Features the nutritional status of children with relapsing respiratory pathology

2019 ◽  
pp. 188-194
Author(s):  
N. A. Druzhinina ◽  
L. M. Nasibullina ◽  
D. R. Merzlyakova ◽  
R. Z. Akhmetshin ◽  
G. P. Shiryaeva ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Preventive Measures ◽  
Component Composition ◽  
Main Group ◽  
The Body ◽  
Control Group ◽  
Healthy Children ◽  
Laboratory Parameters ◽  
Respiratory Pathology ◽  
Nutritional Status Of Children

A survey of 182 children aged 5 to 9 years in the children’s sanatorium «Duslyk» Ufa. A survey of 182 children aged 5 to 9 years in the children’s sanatorium «Duslyk» Ufa.The main group included 101 children with relapsing respiratory pathology, the control group 81 healthy children. The article presents an analysis of the actual weekly diet of children at home, modern approaches to the study of nutritional status using clinical, biochemical, anthropometric, somatometric methods, bioimpedance measurements. The actual nutrition of children with relapsing respiratory pathology was characterized by an imbalance in the content of the main nutrients. A comprehensive assessment of nutritional status revealed malnutrition in children of the main group. The aim of the study was to assess the actual nutrition, the study of nutritional status, taking into account the clinical and laboratory parameters and the component composition of the body of children in the children’s sanatorium. The inclusion of an assessment of actual nutrition and nutritional status in the survey program will make it possible to timely identify malnutrition in children with relapsing respiratory pathology, purposefully carry out preventive measures.

scholarly journals Effectiveness of nutritional status correction in children with cerebral palsy

2021 ◽  
Vol 66 (4) ◽  
pp. 135-140
Author(s):  
A. A. Kamalova ◽  
R. F. Rakhmaeva ◽  
E. M. Ahmadullina ◽  
L. I. Basanova
Keyword(s):  
Body Weight ◽  
Cerebral Palsy ◽  
Nutritional Status ◽  
Nutritional Support ◽  
Skinfold Thickness ◽  
Component Composition ◽  
Physical Rehabilitation ◽  
The Body ◽  
Children With Cerebral Palsy ◽  
Nutritional Status Of Children

The frequency of underweight in children with cerebral palsy is about 60–70%. A benefit of nutritional support in children with cerebral palsy are underestimated. The use of nutritional support during active physical rehabilitation can have a positive effect on not only body weight, but also the component composition of the body and their rehabilitation potential.The aim of our study was to evaluate the effectiveness of nutritional support – a hypercaloric (1,5 kcal/ml) polymer formula with fibers (Pediashure 1,5 Fiber, Abbott) in children with cerebral palsy.Characteristics of children and research methods. Anthropometric indicators (body weight, height, body mass index, triceps skinfold thickness, subscapular skinfold thickness, mid-upper arm circumference, shoulder muscle circumference) and body composition were studied in 15 underweight children with cerebral palsy aged 4–10 years with the level of motor disorders GMFCSIII–IV. They were prescribed of nutritional support with a hyper caloric mixture (1,5kcal/ml) with fiber lasting 3months during active physical rehabilitation.Results. Against the background of nutritional support, there was a significant increase in body weight, height, z-score of body weight, mainly due to musculoskeletal, active cell and lean mass. In addition to correcting the nutritional status of children with cerebral palsy, an improvement in their motor abilities was noted.

scholarly journals The assessment of liver fibrosis in children with obesity on two methods: transient and two dimensional shear wave elastography

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Cristina Oana Mărginean ◽  
Lorena Elena Meliţ ◽  
Dana Valentina Ghiga ◽  
Maria Oana Săsăran
Keyword(s):  
Liver Stiffness ◽  
Shear Wave Elastography ◽  
Tertiary Hospital ◽  
Normal Weight ◽  
The Body ◽  
Control Group ◽  
Study Group ◽  
Healthy Children ◽  
Laboratory Parameters ◽  
And Control

AbstractThe aim of this study was to assess the liver stiffness values in children with obesity versus healthy children on 2D-SWE and TE taking into account different laboratory parameters. We performed a case-control study on 287 children aged between 3 to 18 years, admitted in a Romanian Pediatric Tertiary Hospital, which we divided according to the body mass index (BMI) into two groups: the study group-77 children with obesity, and control group-210 children with normal weight. All children underwent anamnesis, clinical exam, laboratory parameters, ultrasound exam, and elastography. Children with obesity presented higher values of platelets, AST, ALT, and AAR as compared to control group (p = 0.0005/p = 0.0065/p < 0.0001/p < 0.0001). We found no significant differences for APRI between the two groups (p = 0.9827), although the values were higher in children with obesity. Significantly higher values of liver stiffness in children with obesity on both 2D-SWE and TE (p = 0.0314/p < 0.0001) were obtained. Similarly, the velocity values measured by 2D-SWE were also significantly higher in the study group (p < 0.0001). Our findings revealed significantly higher levels of platelets, transaminases, AAR, and liver stiffness values on both TE and 2D-SWE in children with obesity. 2D-SWE and TE might represent useful non-invasive methods for predicting liver impairment associated to pediatric obesity.

scholarly journals Echocardiographic evaluation of ventricular septal defect haemodynamics

2007 ◽  
Vol 135 (9-10) ◽  
pp. 541-546
Author(s):  
Vesna Miranovic
Keyword(s):  
Ventricular Septal Defect ◽  
Pulmonary Artery ◽  
Body Surface ◽  
Septal Defect ◽  
Left Ventricular ◽  
The Body ◽  
Control Group ◽  
Healthy Children ◽  
And Control ◽  
The Relationship

Introduction Ventricular septal defect (VSD) is an opening in the interventricular septum. 30-50% of patients with congenital heart disease have VSD. Objective The aim of the study was to determine the dependence of the left ventricular diastolic dimension (LVD), left ventricular systolic dimension (LVS), shortening fraction (SF), left atrium (LA), pulmonary artery truncus (TPA) on the body surface and compare their values among experimental, control and a group of healthy children. Values of maximal systolic gradient pressure (Pvsd) of VSD were compared with children from one experimental and control group. Method Children were divided into three groups: experimental (32 children with VSD that were to go to surgery), control (20 children with VSD who did not require surgery) and 40 healthy children. Measurements of LVD, LVS, SF, LA, TPA were performed in accordance to recommendations of the American Echocardiographic Association. The value of Pvsd was calculated from the maximal flow velocity (V) in VSD using the following formula: Pvsd=4xV? (mm Hg). Results For children from the experimental group, the relationship between the body surface and the variability of the LVD was explained with 56.85%, LVS with 66.15%, SF with 4.9%, TPA with 58.92%. For children from the control group, the relationship between the body surface and the variability of LVD was explained with 88.8%, LVS with 72.5%, SF with 0.42%, PA with 58.92%. For healthy children, the relationship between the body surface and the variabilitiy of the LVD was explained with 88.8%, LVS with 88.78%, SF with 5.25% and PA with 84.75%. There was a significant statistical difference between average values of Pvsd in the experimental and control group (p<0.02). Conclusion The presence of the large VSD has an influence on the enlargement of LVD, LVS, SF, TPA. The enlargement of the size of the pulmonary artery depends on the presence of VSD and there is a direct variation in the magnitude of the shunt. There is a relationship and significant dependence of the LVS and LVD on the body surface. There is no statistically significant dependence between SF and body surface.

scholarly journals Mechanisms of psychological defense and strategies of control stress of mothers who have children suffering from cerebral paralysis

2006 ◽  
Vol 5 (2) ◽  
pp. 107-113
Author(s):  
L. M. Kolpakova
Keyword(s):  
Preventive Measures ◽  
Analysis Data ◽  
Control Group ◽  
Healthy Children ◽  
Adaptive Potential ◽  
Psychological Defense ◽  
Adaptive Mechanisms ◽  
Cerebral Paralysis ◽  
Controlling Behavior ◽  
Life Analysis

The problem of studying adaptive potential of mothers who have children with cerebral paralysis is considered which may be useful for the choice of diagnosis and preventive accesses in the framework of preventive measures directed to the prevention of disturbances of personality and diseases under stress events of life. Analysis data of mechanisms’ structure of psychological defense in the age dynamics compared to control group of women having healthy children. Psychological adaptive mechanisms are differentiated which help to transform negative internal emotions into more adequate form taking into account specificity of the situation in which mothers with such children are. Mechanisms of controlling behavior are revealed which have preventive function and increase personal resources of women-mother in the situation of stress events which are associated with her child disease.

scholarly journals Роль материнских полиморфных вариантов гена HLA-G3'UTR 14-bp *ins/del в реализации генетического детерминирования риска формирования спорадических септальных врожденных пороков сердца без хромосомных болезней

2019 ◽  
Author(s):  
A.V. Shabaldin ◽  
A.V. Tsepokina ◽  
A.V. Ponasenko ◽  
E.V. Shabaldina
Keyword(s):  
Heart Defects ◽  
Main Group ◽  
Control Group ◽  
Healthy Children ◽  
Rt Pcr ◽  
Homozygous Genotype ◽  
Xenobiotic Biotransformation ◽  
Pcr Method ◽  
Mathematical Processing ◽  
Chromosomal Diseases

Врожденные пороки сердца (ВПС) являются ведущей патологией среди всех пороков и аномалий развития плода. Известно, что тератогенный эффект ксенобиотика будет максимально представлен при нарушенных иммунных взаимодействиях в системе мать-эмбрион . Неоднократно показано, что женский гомозиготный генотип HLA-G 3UTR 14-bp ins/ins ассоциирован с репродуктивными потерями. Цель исследования. Изучить распределение аллелей и генотипов генов биотрансформации ксенобиотиков у женщин, имеющих детей с ВПС, носительниц вариантных генотипов HLA-G 3UTR 14-bp ins/del. Материал и методы. Обследованы 103 женщины, у которых дети при рождении имели врожденный порок сердца без хромосомных заболеваний и родословной историей, а также 103 женщины (контрольная группа), родивших двух здоровых детей и более. Типирование полиморфных сайтов генов HLA-G 3UTR 14-bpins/del, GSTM1 (rs74837985), CYP1A1 (rs1048943) CYP1A2 (rs35694136, rs762551) GSTT1 (rs2266633, rs2266637, rs2234953) GSTP1 (rs6591256, rs1695, rs1871042, rs1793068), GATA 6 (rs10454095) проводили методом RT-PCR. Результаты. Показано, что у женщин основной группы, являющихся носительницами гомозиготного генотипа 14-bp ins/ins HLA-G 3UTR, статистически значимо чаще встречались гетерозиготные генотипы GSTP1 (rs6591256) A/G (р0,01 отношение шансов ОШ5,1, 2,5710,27), GSTP (rs1793068) G/T (р0,01 ОШ5,1, 2,5710,27), CYP1A2 (rs762551) A/C (р0,01 ОШ6,81, 3,3513,73) и гомозиготный минорный генотип GSTP1 (rs1871042) T/T (р0,001 ОШ7,32, 3,6214,76) по сравнению с группой контроля. В основной группе женщин G/G rs74837985 GSTM1 статистически значимо реже (р0,01 ОШ 0,20, 0,06-0,59) встречался у носительниц 14-bp ins/ins HLA-G 3UTR по сравнению с носительницами гетерозиготного генотипа 14-bp ins/del HLA-G 3UTR. Заключение. В ходе исследования установлено, что при одновременном носительстве мутантных аллелей HLA-G и генов системы транформации ксенобиотиков риски рождения детей с дефектом межжелудочковой перегородки выше, чем при носительстве изолированных мутаций.Congenital heart defects (CHD) are the leading pathologies among all congenital malformations and fetal development abnormalities. It is known that the teratogenic effect of xenobiotic will be maximally presented in the case of disturbed immune interactions in the mother-embryo system. It has been repeatedly shown that the female homozygous genotype HLA-G 3UTR 14-bp ins/ins is associated with reproductive losses. The purpose of this study was to study the distribution of alleles and genotypes of xenobiotic biotransformation genes in women with children with CHD, carriers of variant HLA-G 3UTR 14-bp ins/del genotypes. Material and method: It was examined 103 women whose children had a ventricular septal defect (VSD) without chromosomal diseases and a pedigree history at birth, and 103 women (control group) who gave birth to two or more healthy children. The typing of polymorphic sites of the genes HLA-G 3UTR 14-bp ins/del, GSTM1 (rs74837985), CYP1A1 (rs1048943) CYP1A2 (rs35694136, rs762551) GSTT1 (rs2266633, rs2266637, rs2234953) GSTP1 (rs6591256, rs1695, rs1871042, rs1793068), GATA 6 (rs10454095) was performed by the RT-PCR method. Mathematical processing was carried out using the application software STATISTICA 8.0 (StatSoftInc., USA) and SNPstats. Results: It was shown that the heterozygous genotypes GSTP1 (rs6591256) A / G (p0.01, OR5.1 (2.5710.27)), GSTP (rs1793068) G / T (p0.01, OR5.1 (2.5710.27)), CYP1A2 (rs762551) A/C (p0.01, OR6.81 (3.3513.73)) and the homozygous minor genotype GSTP1 (rs1871042) T/T (p0.001, OR7.32 (3.6214.76) ) were statistically significantly more frequent in the main group of women who are carriers of the homozygous genotype 14-bp ins/ins HLA-G 3UTR, in comparison with the control group. In the main group of women G/G rs74837985 GSTM1 statistically significantly less (p0.01, OR0.20 (0.060.59)) was found in carriers of 14-bp ins / ins HLA-G 3UTR, in comparison with carriers of the heterozygous genotype 14-bp ins/del HLA-G 3UTR. Conclusion: It was found that with the simultaneous carrier of the mutant alleles of HLA-G and the genes of the xenobiotics transformation system, the risk of having children with VSD is higher, compared with the carriage of isolated mutations.

scholarly journals Nutritional status of school children living in Northern part of Sri Lanka

2020 ◽  
Author(s):  
Gitanjali Sathiadas ◽  
A Annieston ◽  
V Arunath ◽  
T Kasthuri ◽  
V P Wickramasinghe
Keyword(s):  
Sri Lanka ◽  
Nutritional Status ◽  
School Children ◽  
Household Income ◽  
Maternal Education ◽  
Overweight And Obesity ◽  
The Body ◽  
Healthy Children ◽  
Important Indicator ◽  
Height For Age

Abstract Background Nutritional status is an important indicator for measuring quality of life in children. A region that is recovering from war will face many problems related to nutrition. Very few studies have addressed the nutritional problems in school-going children. This study was undertaken to identify the prevalence of wasting, stunting and obesity of school children from Northern Sri Lanka and associated socio-demographic factorsMethods A community based cross-sectional study was carried out using multistage stratified proportionate cluster among healthy children attending schools in the Northern part of the country. Height and weight were measured and the Body Mass Index (BMI) was calculated [weight (kg)/Height (m) ²]. BMI-for-age z-score (BAZ) and Height for age Z (HAZ) scores were determined and WHO growth references were used to categorise the nutritional status of the children. Correlation between various nutritional problems with Maternal education, household income, number of family members and the residential area was assessed. Results A total of 1012 children were recruited, and the mean age and standard deviation were 11.12±1.77yrs. Girls in the age ranges of 9-14 were heavier and taller when compared to the boys compatible to the pubertal growth spurt. Stunting based on the height for age was seen in 10.9% of boys and 11.8% of girls. Wasting based on BMI for age WHO standard (WHO 2007) was seen in 30.6% of boys and 29.1% of the girls. The prevalence of overweight was 11% and Obesity was 6.3% of the population. Obesity was predominantly seen in boys (4.2%) and it was significantly higher when compared to the girls (2.1%) (p <0.001). Older boys (>10 years) were significantly affected more than the younger ones (p <0.01). The prevalence of wasting, stunting, overweight and obesity had significant variations in different educational zones comparable with the geographical areas. Maternal Education and Family income had a significant impact on the prevalence of stunting and obesity. (p<0.001) whereas the family size significantly contributed to the wasting and obesity. Conclusion Findings suggest that stunting, wasting, overweight and obesity are prevalent among 6-16-year-old leading to concerns in public health. The nutritional status significantly vary according to the geographical location maternal education and the household income.

scholarly journals Hubungan Asupan Energy Dengan Status Gizi Anak Pra Sekolah Usia 4-5 Tahun Di TK Al Islam Jamsaren Surakarta

2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Anik Kurniawati ◽  
Endang Suwanti
Keyword(s):  
Nutritional Status ◽  
Energy Intake ◽  
Target Population ◽  
The Body ◽  
School Age Children ◽  
Rank Test ◽  
P Value ◽  
Cross Sectional ◽  
Two Factors ◽  
Nutritional Status Of Children

Background: The nutritional status of children is influenced by two factors, namely the direct factor in food intake and infectious diseases and indirect causes. Nutritional factors are known to play an important role in determining the growth of a child. When experiencing growth, cells in the body need energy to divide, if energy requirements are not met, cell division will be inhibited and the effect will be seen through anthropometric and biochemical parameters. Objective, To determine the relationship between energy intake and nutritional status of preschoolers aged 4-5 years at Al Islam 1 Jamsaren Kindergarten in Surakarta. The research hypothesis, there is a relationship between energy intake and nutritional status of pre-school age children 4-5 years old at Al Islam Jamsaren Kindergarten in Surakarta. Method: This type of research is this study using a cross sectional approach. The target population in this study was the population in this study were all mothers and children aged 4-5 years in Al Islam 1 TK Jamsaren Surakarta totaling 89 people. Samples were taken by purposive technique with a sample of 47 respondents. Analysis of sperman rank test data. Results: Showed that the majority of respondents had a moderate energy intake of 17 (36.2%) respondents and most had good nutritional status 38 (80.8%) respondents. Conclusion: There is a relationship between energy intake and the nutritional status of pre-school children aged 4-5 years in Surakarta Jamsaren Kindergarten with p value 0.02.

scholarly journals Lingkungan Fisik Kamar Tidur dan Pneumonia pada Anak Balita di Puskesmas Kawalu Kota Tasikmalaya

2007 ◽  
Vol 2 (2) ◽  
pp. 64
Author(s):  
Nur Widodo
Keyword(s):  
Nutritional Status ◽  
Interaction Analysis ◽  
Public Health Problem ◽  
Case Control ◽  
Healthy Children ◽  
Mosquito Coil ◽  
Important Public Health Problem ◽  
Poor Nutritional Status ◽  
Nutritional Status Of Children ◽  
The Relationship

Pneumonia masih menjadi masalah kesehatan masyarakat yang penting di Indonesia termasuk di Kota Tasikmalaya. Diperkirakan proporsi penyakit pneumonia bayi adalah 16,4%, dan pada balita adalah 25%. Tujuan penelitian ini adalah untuk mengetahui hubungan kejadian pneumonia pada balita dengan faktor lingkungan fisik kamar tidur dan karakteristik anak. Desain penelitian yang digunakan adalah case control. Sampel sebanyak 300 responden terdiri dari 150 orang kasus dan 150 orang kontrol. Dari hasil uji multivariat tanpa interaksi, faktor dominan yang mempengaruhi kejadian penyakit pneumonia pada anak balita adalah status gizi dengan nilai B 1,799 dan OR = 6,041 (CI 95%=1,607-22,713). Sedangkan hasil uji interaksi diperoleh hasil bahwa faktor dominan yang mempengaruhi kejadian pneumonia anak balita adalah interaksi antara asap obat nyamuk dengan status gizi dengan nilai B 1,040 dan OR=2,828 (CI 95%=1,667-4,7988). Pada perhitungan probabilitas didapatkan hasil bahwa balita yang menderita pneumonia memiliki probabilitas odds 15,6 kali punya riwayat status imunisasi tidak lengkap (DPT dan Campak), status gizi kurang dan ada asap obat nyamuk bakar di dalam kamar tidur dibanding balita yang tidak menderita pneumonia. Disarankan agar anak balita diimunisasi lengkap (DPT dan Campak), diberi asupan makanan dengan gizi seimbang, dan tidak menggunakan obat anti nyamuk bakar di dalam kamar tidur, serta perlu disosialisasikan faktor-faktor yang berhubungan dengan kejadian pneumonia pada balita.Kata kunci: Pneumonia, balita, kamar tidurAbstractPneumonia is still an important public health problem in Indonesia, especially in Tasikmalaya city, West Java. It was predicted that pneumonia contributed to fetal death at about 16.4%, while the incidence of the pneumonia among under 5 years children is 25%. The objective of this study is to know the relationship between physical environment of baby sleeping room and pneumonia. Design of the study used is case control study. The sample size is 300 subjects consists of 150 cases and 150 controls. Based on multivariate analysis, the nutritional status of children relate closely with pneumonia (OR = 6.041; 95% CI =1.607- 22.713). While from an interaction analysis it was found that there is an interaction effect of mosquito coil and nutritional status on pneumonia (OR=2.828 ;CI 95%= 1.667-4.7988). Based on probability computation it was known that under 5 years old children who suffer from pneumonia has probability odds of 15.6 times has incomplete diphteria and measles immunization, poor nutritional status, and using mosquito coil compared to healthy children. Under five years children is recommended to get complete DPT and measles immunization, provided balance nutritional intake and not using mosquito coil in sleeping room.Keywords : Pneumonia, under 5 years children, sleeping room

scholarly journals Features of the second half of pregnancy in women with labor abnormalities

2021 ◽  
Vol 14 (6) ◽  
pp. 659-665
Author(s):  
U. G. Shokirova ◽  
S. P. Pakhomov ◽  
A. S. Ustyuzhina ◽  
A. V. Matrosova
Keyword(s):  
Laboratory Data ◽  
International Normalized Ratio ◽  
Study Data ◽  
Main Group ◽  
Individual Risk ◽  
Control Group ◽  
Systematic Analysis ◽  
Laboratory Parameters ◽  
Blood Biochemical ◽  
Labor Abnormalities

Aim: conduct a systematic analysis of pregnancy development, investigate clinical and laboratory data affecting development of labor abnormalities in women residing in the Belgorod region. Materials and Methods. From 2014 to 2018, 484 women were examined and divided into 2 groups: main group consisted of those who had childbirth complicated with labor abnormalities (n = 344), whereas control group consisted of women lacking complications during delivery (n = 140). The following methods were used in the study: questionnaires, general clinical methods, biochemical blood tests in pregnant and postpartum women, populational statistics as well as methods of standard and multivariate statistics. Results. In the second half of pregnancy in women with labor abnormalities revealed higher rate of moderate preeclampsia (34.30 ± 2.56 % vs. 10.71 ± 2.61%; p < 0.05), polyhydramnios (11.34 ± 1.71 % vs. 5.71 ± 1.96 %; p < 0.05), chronic intrauterine hypoxia (29.6 ± 2.46 % vs. 12.86 ± 2.83 %; p < 0.05), chronic utero-placental insufficiency (60.47 ± 2.64 % vs. 20.00 ± 3.38 %; p < 0.05), sexually transmitted infections (3.78 ± 1.03 % vs. 0.71 ± 0.71 %; p < 0.05), acute respiratory viral infection (8.72 ± 1.52 % vs. 3.57 ± 1.57 %; p < 0.05) as well as a combination of several types of pathology (8.72 ± 1.52 % vs. 13.57 ± 2.89 %; p < 0.05). Laboratory parameters in women with labor abnormalities compared with control antepartum group were noted to have significantly decreased count of red blood cells (3.89 ± 0.38×1012/L vs. 3.99 ± 0.40×1012/L; p = 0.006), eosinophils (0.95 ± 0.69×109/L vs. 1.20 ± 0.67×109/L; p = 0.026) and platelets (226.29 ± 62.71×109/L vs. 245.44 ± 60.32×109/L; p = 0.0003). Blood biochemical parameters in women with labor abnormalities vs. control group were featured with significantly decreased level of bilirubin (6.76 ± 3.16 μmol/L vs. 9.88 ± 3.60 μmol/L; p < 0.05) and alanine aminotransferase (13.94 ± 10.08 U/L vs. 19.41 ± 14.40 U/L; p = 0.004). Analyzing coagulation parameters in the main group showed significantly reduced fibrinogen level (4.30 ± 1.00 g/L) compared with control group (4.71 ± 1.14 g/L; p < 0.05) as well as elevated international normalized ratio (1.07 ± 0.11 vs. 1.03 ± 0.10; p = 0.001). Conclusion. Our study data found that pregnant women with labor abnormalities had altered clinical and laboratory parameters observed as early as in the second half of gestation, which may be used to calculate an individual risk of such labor complication.

scholarly journals Surgical treatment of acetabular fractures

TRAUMA ◽  
2021 ◽  
Vol 22 (4) ◽  
pp. 46-51
Author(s):  
I.I. Trufanov
Keyword(s):  
Surgical Treatment ◽  
Road Traffic ◽  
Platelet Rich Plasma ◽  
Clinical Effectiveness ◽  
Postoperative Management ◽  
Main Group ◽  
The Body ◽  
Social Adaptation ◽  
Acetabular Fractures ◽  
Control Group

Background. Acetabular fractures are severe intra-articular injuries that require anatomical reposition and early function, but they are often complicated by degenerative changes in both the acetabulum and the femoral head, leading to the development of post-traumatic coxarthrosis. The purpose was to study the clinical effectiveness of surgical treatment and postoperative management of patients using autologous platelet-rich plasma in patients with fractures of the acetabulum. Materials and methods. Twenty-eight patients with acetabular fractures of various degrees were operated at the City Emergency Hospital of Zaporizhzhia and the Municipal Clinical Hospital No 9 from 2017 to 2019. Gender composition: 22 men (78.57 %), 6 women (21.43 %), average age 46.64 ± 2.21 years, with a 95% confidence interval 42.31–50.96. Nineteen victims (67.86 %) had road traffic injuries, 7 (25 %) domestic injuries, and 2 (7.14 %) had industrial injuries. Results. In the main group of patients treated with platelet-rich plasma, radiologically visible adhesion of the injured area after 8 weeks occurred in 10 people (83.4 %). In one person (8.3 %), the adhesion occurred after 12, and in another (8.3 %) — 16 weeks after surgery. In the control group, adhesions at 8th week were registered in 14 patients (60.87 %), in 8 (34.78 %) — at 16th week. Given the general recovery of the body in the main group, the activation and social adaptation of patients occurred 2–3 weeks earlier. The assessment was performed radiologically and by the criteria of functional recovery.

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