scholarly journals The relationship between overweight and female infertility

2021 ◽  
Vol 11 (4) ◽  
pp. 3-10
Author(s):  
Maíra Masello da Costa ◽  
Caroline Brandão Andrade ◽  
Francisca Valdenia Guerreiro Soares ◽  
Gabriella Pinto Belfort

Excessive weight seems to negatively influence fertility, and as it is a modifiable factor, understanding this relationship can contribute to infertility treatment. Adipose tissue is responsible for releasing several hormones and cytokines related to the reproductive system, such as leptin, TNF-a, and Interleukin-6, substances that can negatively impact female fertility. Additionally, a woman's diet and lifestyle can influence body weight and fertility. Food consumption, characterized by a high intake of foods with high energy density, high levels of sugar, saturated fat, and poor nutrients, as well as physical inactivity, can favor excessive weight. Thus, losing body weight obtained through a healthy diet associated with physical activity may restore fertility in overweight women.

Author(s):  
Hubert Dobrowolski ◽  
Dariusz Włodarek

The outbreak of the COVID-19 pandemic caused a number of changes in social life around the world. In response to the growing number of infections, some countries have introduced restrictions that may have resulted in the change of the lifestyle. The aim of our study was to investigate the impact of the lockdown on body weight, physical activity and some eating habits of the society. The survey involving 183 people was conducted using a proprietary questionnaire. The mean age of the study participants was 33 ± 11 and mean height 169 ± 8 cm. An average increase in body weight was observed in 49.18% by 0.63 ± 3.7 kg which was the result of a decrease in physical activity and an increase in food consumption. We also observed a decrease in PAL from 1.64 ± 0.15 to 1.58 ± 0.13 and changes in the amount of food and individual groups of products consumption, including alcohol. Among the study participants who did not lose body mass, there was an average weight gain of 2.25 ± 2.5 kg. In conclusion, an increase of weight was shown in about half of the respondents in the study group which was associated with a decrease in physical activity and an increase in the consumption of total food and high energy density products.


2004 ◽  
Vol 286 (4) ◽  
pp. R669-R677 ◽  
Author(s):  
Qinmin Zhang ◽  
Michael G. Tordoff

Recent epidemiological and animal studies have led to the hypothesis that low dietary calcium intakes contribute to obesity. Here, we evaluated whether calcium influenced the body weight of normal-weight and obese rodents. All experiments involved female C57BL/6J mice or Sprague-Dawley rats fed normal- or high-energy-density diets (3.8 or 4.7 kcal/g). Calcium intake was manipulated by allowing mice to drink sweetened 30 mM CaCl2 solution or feeding mice and rats diets differing in calcium content (0.2%, 0.6%, or 1.8% Ca2+). Blood samples were taken from rats to confirm that the diets had their intended effects on metabolism. There were no effects of the calcium manipulations on energy intake, body weight, or carcass fat content and no simple relation between calciotropic hormones and body weight. One experiment found a significant decrease in body weight gain of lean and obese rats fed the 1.8% Ca2+ diet, but we suspect that this was due to forced consumption of the unpalatable diet, reducing growth. These studies provide little support for the hypothesis that dietary calcium contributes to the etiology or maintenance of obesity.


2020 ◽  
Author(s):  
Dulce M. Minaya ◽  
Anna Turlej ◽  
Abhinav Joshi ◽  
Tamas Nagy ◽  
Patricia Di Lorenzo ◽  
...  

AbstractObesity is a multifactorial chronic inflammatory disease. Consumption of high energy density (ED) diets is associated with hyperphagia, increased body weight and body fat accumulation, and obesity. Our lab has previously shown that short-term (4 weeks) consumption of a high ED diet triggers gut microbiota dysbiosis, gut inflammation, and reorganization of the gut-brain vagal communication. The aim of the current study was to investigate the effect of long-term (6 months) consumption of high ED diet on body composition, gut microbiome, hepatocellular lipidosis, microglia activation in the Nucleus of the Solitary Tract, and the development of systemic inflammation. Male Sprague-Dawley rats were fed a low ED diet (5% fat) for two weeks and then switched to a high ED (45% fat) diet for 26 weeks. Twenty-four hour food intake, body weight, and body composition were measured twice a week. Blood serum and fecal samples were collected at baseline, and 1, 4, 8, and 26 weeks after introduction of the high ED diet. Serum samples were used to measure insulin, leptin, and inflammatory cytokines using Enzyme-linked Immunosorbent Assay. Fecal samples were used for 16S rRNA genome sequencing. High ED diet induced microbiota dysbiosis within a week of introducing the diet. In addition, there was significant microglia activation in the intermediate NTS and marked hepatic lipidosis after four weeks of high ED diet. We further observed changes in the serum cytokine profile after 26 weeks of high ED feeding. These data suggest that microbiota dysbiosis is the first response of the organism to high ED diets and this, in turn, detrimentally affects liver fat accumulation, microglia activation in the brain, and circulating levels of inflammatory markers.


2019 ◽  
Vol 21 (43) ◽  
pp. 24034-24041
Author(s):  
Chuli Sun ◽  
Weijing Zhang ◽  
Yongjun Lü ◽  
Feng Wang ◽  
Wei Guo ◽  
...  

Studies on the relationship between the microscopic properties and macroscopic behaviors of energetic compounds may provide clues for the synthesis and assessment of novel high energy density materials.


Polymers ◽  
2021 ◽  
Vol 13 (23) ◽  
pp. 4202
Author(s):  
Yingjie Jiang ◽  
Yujia Li ◽  
Haibo Yang ◽  
Nanying Ning ◽  
Ming Tian ◽  
...  

The dielectric elastomer (DE) generator (DEG), which can convert mechanical energy to electrical energy, has attracted considerable attention in the last decade. Currently, the energy-harvesting performances of the DEG still require improvement. One major reason is that the mechanical and electrical properties of DE materials are not well coordinated. To provide guidance for producing high-performance DE materials for the DEG, the relationship between the intrinsic properties of DE materials and the energy-harvesting performances of the DEG must be revealed. In this study, a simplified but validated electromechanical model based on an actual circuit is developed to study the relationship between the intrinsic properties of DE materials and the energy-harvesting performance. Experimental verification of the model is performed, and the results indicate the validity of the proposed model, which can well predict the energy-harvesting performances. The influences of six intrinsic properties of DE materials on energy-harvesting performances is systematically studied. The results indicate that a high breakdown field strength, low conductivity and high elasticity of DE materials are the prerequisites for obtaining high energy density and conversion efficiency. DE materials with high elongation at break, high permittivity and moderate modulus can further improve the energy density and conversion efficiency of the DEG. The ratio of permittivity and the modulus of the DE should be tailored to be moderate to optimize conversion efficiency (η) of the DEG because using DE with high permittivity but extremely low modulus may lead to a reduction in η due to the occurrence of premature “loss of tension”.


2021 ◽  
Vol 11 (2) ◽  
pp. 178
Author(s):  
Ewa Racicka-Pawlukiewicz ◽  
Katarzyna Kuć ◽  
Maksymilian Bielecki ◽  
Tomasz Hanć ◽  
Anita Cybulska-Klosowicz ◽  
...  

Despite the increasing body of research on Attention Deficit Hyperactivity Disorder (ADHD), the results of the studies assessing the relationship between executive function deficit and the risk of obesity in people with ADHD are incongruent. Our study aimed to assess the relationship between measures of executive functions and body weight and Body Mass Index (BMI) in children and adolescents with ADHD and control subjects. The study group consisted of 58 subjects aged from 8 to 17 years with ADHD. The Control group consisted of 62 healthy age and sex-matched participants from primary and secondary schools. Weight, height, and BMI measurements were standardized. The Sustained Attention to Response Test (SART) and the Attention Network Test (ANT) were used to assess executive functions. Based on the analysis of the correlation and analysis of moderation, we found that subjects with higher weight in the study group presented a lower efficiency of the inhibition processes and gave more impulsive and incorrect answers. The occurrence of impulsive reactions might contribute to the risk of excessive weight in children and adolescents with ADHD.


Author(s):  
Jennifer L. Temple ◽  
Amanda M. Ziegler ◽  
Amanda K. Crandall ◽  
Tegan Mansouri ◽  
Lori Hatzinger ◽  
...  

Abstract Background/Objectives Characterizing behavioral phenotypes that predict increased zBMI gain during adolescence could identify novel intervention targets and prevent the development of obesity. The purpose of this study was to determine if sensitization of the relative reinforcing value (RRV) of high (HED) or low energy density (LED) foods predicts adolescent weight gain trajectories. A secondary aim was to test the hypothesis that relationships between sensitization of the RRV of food and weight change are moderated by delay discounting (DD). Subjects/Methods We conducted a prospective, longitudinal cohort study in 201 boys and girls with an average zBMI of 0.4, who began the study between the ages of 12 and 14 years and completed the study 2 years later. Participants completed five laboratory visits where the RRV of HED and LED, and DD were assessed at a baseline (visits 1, 2, and 4) and then RRV was measured again after participants consumed a portion of the same HED and LED food for 2 weeks (visits 3 and 5; order counterbalanced). Increases (>1) in the RRV from baseline to post-daily intake were categorized as “sensitization” and decreases (≤1) were categorized as “satiation.” Participants returned to the laboratory for follow-up visits at 6, 15, and 24 months to have height and weight taken and to complete additional assessments. Results Sensitization to HED food was associated with a greater zBMI change over time (β = 0.0070; p = 0.035). There was no impact of sensitization to LED food or interaction between sensitization to HED and LED food on zBMI change and no moderation of DD on the relationship between HED sensitization and zBMI change (all p > 0.05). Conclusion Our prior work showed that sensitization to HED food is cross-sectionally associated with greater zBMI. This study extends this work by demonstrating that sensitization to HED food prospectively predicts increased zBMI gain over time in adolescents without obesity. Future studies should determine if sensitization can be modified or reduced through behavioral intervention. Trial registration Clinicaltrials.gov: NCT04027608.


Author(s):  
Susanne-Marie Kirsch ◽  
Felix Welsch ◽  
Domenico Bevilacqua ◽  
David Naso ◽  
Stefan Seelecke ◽  
...  

Abstract Shape memory alloys (SMA) are used as an attractive technology in the field of actuators and sensors due to their versatile geometry, lightweight, high energy density, and low cost. The thermal activation principle, however, makes SMA application generally suitable for low-frequency (few Hz) regimes. In this work, a novel SMA-based antagonistic actuation system and its manufacturing process are presented for the first time. The main feature of the novel actuator concept is the possibility of being operated at frequencies up to at least 20 Hz. It spares the usual complex and time-consuming manufacturing of such a system. First parameter studies of a rotary actuation system are performed. The relationship existing between the pulse energy, frequency, and the resulting rotation angle is investigated through an extensive experimental campaign.


1987 ◽  
Vol 44 (2) ◽  
pp. 209-217 ◽  
Author(s):  
T. W. Gettys ◽  
D. M. Henricks ◽  
P. M. Burrows ◽  
B. D. Schanbacher

ABSTRACTFour groups of calves (10 bulls, 10 steers, 10 heifers and 10 ovariectomized heifers) of Simmental- Hereford breeding were individually given a high-energy diet from 10 to 16 months of age. At the end of the experiment, the 9-10-11th rib section was dissected into fat, lean and bone and chemical analysis was performed on the dissected soft tissue. For each group, the relationship between food intake and change in body weight was examined by a method designed to separate intake into its simultaneous maintenance and gain components: least-squares estimates for the maintenance coefficient (βm, kg/day per kg body weight) and the gain coefficient (βg, kg food per kg gain) were obtained for each animal. Conventional measures of food conversion ratio (kg food per kg gain) were examined on both common age and common weight-gain bases. Bulls, followed by steers, accumulated the most lean and least fat while heifers and ovariectomized heifers accumulated the least lean and most fat. Maintenance coefficients (βm) were lower in males than in females but did not differ within gender. Gain coefficients (βg) did not differ among the groups, although the coefficients appeared to be similar within gender. Food conversion ratio computed over a common age interval did not differ among groups. Food conversion ratio computed over common weight intervals was lowest in bulls followed in increasing order by steers then the two female groups. It is concluded that males grow more efficiently than females while accumulating more lean and less adipose tisue and that this greater efficiency is achieved by consuming less food per unit of body weight for maintenance, leaving proportionately more of the total intake available for gain.


Aerospace ◽  
2004 ◽  
Author(s):  
Vishnu Baba Sundaresan ◽  
Honghui Tan ◽  
Donald J. Leo ◽  
John Cuppoletti

Biological systems such as plants produce large deformations due to the conversion of chemical energy to mechanical energy. These chemomechanical energy conversions are controlled by the transport of charge and fluid across permeable membranes within the cellular structure of the biological system. In this paper we analyze the potential for using biological transport mechanisms to produce materials with controllable actuation properties. An energetics analysis is performed to quantify the relationship between the introduction of chemical energy in the form of ATP to the resulting osmotic pressure variation within an enclosed membrane. Our analysis demonstrates that pressure variations of between 5 and 15 MPa are achievable. The pressure variations are then coupled to a finite element analysis to determine the ability of organized arrays to produce extensional and bending actuation in thin membranes. Our analysis demonstrates that internal pressure variations on the order of 10 MPa can produce actuation materials with extensional energy density on the order of 100 kJ/m3 and bending energy density on the order of 10 kJ/m3.


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