scholarly journals DIAGNOSTIC AND PREDICTIVE SIGNIFICANCE OF LABORATORY DIAGNOSTIC METHODS IN HEMATOLOGICAL PRACTICE

2021 ◽  
Vol 2 (1(82)) ◽  
pp. 9-15
Author(s):  
В. Середин
Keyword(s):  
Diagnostic Methods ◽  
Practical Significance ◽  
Diagnostic Utility ◽  
Pathological State ◽  
Laboratory Practice ◽  
Is Research ◽  
Prognostic Utility ◽  
Health And Disease ◽  
And Behavior

The aim of the paper is research of the diagnostic and prognostic utility of laboratory-based methods diagnostic in hematological practice, formulation of rational scientifically based methods of strategy and behavior tactics of the doctor in pathological state. Questions on diagnostic and practical significance of laboratory – based methods of people’s pathological state diagnostic, which are used in clinical and laboratory practice are studied. Methods and procedure of diagnostic utility valuation in health and disease were studied.

scholarly journals Biological autoluminescence for assessing oxidative processes in yeast cell cultures

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Petra Vahalová ◽  
Kateřina Červinková ◽  
Michal Cifra
Keyword(s):  
Reactive Oxygen Species ◽  
Light Emission ◽  
Reactive Oxygen ◽  
Modern Medicine ◽  
Diagnostic Methods ◽  
Pathological State ◽  
Oxygen Species ◽  
Non Invasive ◽  
Oxidative Processes ◽  
Physical And Chemical

AbstractNowadays, modern medicine is looking for new, more gentle, and more efficient diagnostic methods. A pathological state of an organism is often closely connected with increased amount of reactive oxygen species. They can react with biomolecules and subsequent reactions can lead to very low endogenous light emission (biological autoluminescence—BAL). This phenomenon can be potentially used as a non-invasive and low-operational-cost tool for monitoring oxidative stress during diseases. To contribute to the understanding of the parameters affecting BAL, we analyzed the BAL from yeast Saccharomyces cerevisiae as a representative eukaryotic organism. The relationship between the BAL intensity and the amount of reactive oxygen species that originates as a result of the Fenton reaction as well as correlation between spontaneous BAL and selected physical and chemical parameters (pH, oxygen partial pressure, and cell concentration) during cell growth were established. Our results contribute to real-time non-invasive methodologies for monitoring oxidative processes in biomedicine and biotechnology.

Conditions for the development of the philosophy of non-violence in the modern world

2020 ◽  
pp. 337-352
Author(s):  
Tolganay V. Mustafina-Kulchmanova ◽  
Zhabayhan M. Abdildin ◽  
Kudaibergen A. Temirgaliev ◽  
Kuralay S. Yermagambetova ◽  
Manifa S. Sarkulova
Keyword(s):  
Public Opinion ◽  
Comparative Study ◽  
Political Science ◽  
Practical Significance ◽  
Modern World ◽  
Practical Application ◽  
Theoretical Methods ◽  
University Teachers ◽  
Analysis And Synthesis ◽  
And Behavior

This article addresses the issues of the genesis of non-violence and the practical application of non-violent practices in the context of modern realities. The phe-nomenon of non-violence is seen in close connection with violence, which is more often reflected in the form of wars, military clashes, and conflicts. The article pro-vides an analysis of the use of non-violent practices and the possibility of develop-ing peacekeeping in public opinion and behavior. During the preparation of this article, a review and comparative study of various literature aimed at studying non-violence were carried out. Together with the philosophical works, various ma-terials of a political science character are studied. In preparing this work, they were used as general theoretical methods, such as analysis and synthesis. At the same time, analogies, systematization, etc. were used. The materials of the article sug-gest practical significance for university teachers of humanitarian/philosophical specialties.

scholarly journals STATUS AND CLASSIFICATIONS OF SLOGANES IN ADVERTISING COMMUNICATION

THE BULLETIN ◽  
2021 ◽  
Vol 2 (390) ◽  
pp. 146-153
Author(s):  
L. Savchenko ◽  
S. Tovkach ◽  
A. Shilina ◽  
N. Yablonovskaya ◽  
O. Subbotina ◽  
...  
Keyword(s):  
Comparative Method ◽  
Practical Significance ◽  
Advertising Campaign ◽  
Continuous Sampling ◽  
Linguistic Unit ◽  
Autonomous Element ◽  
Advertising Appeal ◽  
General Scientific ◽  
And Behavior ◽  
Advertising Communication

An advertising slogan is a special genre of advertising text that acts as a connecting link in the entire advertising campaign. In addition, slogans also perform a number of other functions, being the most important unit of advertising communication, they influence the recipients of information, affect their emotions and behavior. The relevance of the topic is due to the increased interest in the rapidly developing language of advertising. The article is devoted to general issues of the functioning of an advertising slogan in the structure of advertising activities, classification of slogans in advertising communication. Research methods are determined by the goals and objectives of the work. In a complex linguistic analysis, the following general scientific theoretical methods are used: the continuous sampling method, the descriptive-analytical method, the comparative-comparative method. The theoretical significance of this study lies in the expansion, deepening and systematization of theoretical information about the concept of an advertising slogan. The scientific and practical significance of the work lies in the fact that the materials of the study can be used in theoretical courses on advertising in the study of intercultural communication. Results. The totality of the typological characteristics of the slogan distinguishes it from the background of other verbal units of advertising appeal. These are laconicism and imagery of form, expressiveness, focus on dialogue with the addressee. The slogan of a product that is just entering the market must contain the brand name. This will allow the consumer to be remembered faster. Having analyzed the functions and typological characteristics of the slogan, we came to the conclusion that the slogan is a key autonomous element of the advertising message and can be used both in the context of advertising, being its component, and separately, having semantic, structural, compositional features. The slogan can act as a linguistic unit, independent of other elements of the advertising text, expressing the essence of the advertising campaign, the company's image, the dominant idea. Thus, the changes caused by extralinguistic factors inevitably lead to the creation of new advertising images, which in turn requires a qualitative transformation of the nature of the advertising text and the emergence of new advertising slogans.

scholarly journals Prenatal Developmental Origins of Future Psychopathology: Mechanisms and Pathways

2019 ◽  
Vol 15 (1) ◽  
pp. 317-344 ◽  
Author(s):  
Catherine Monk ◽  
Claudia Lugo-Candelas ◽  
Caroline Trumpff
Keyword(s):  
Maternal Distress ◽  
Developmental Origins ◽  
Neurodevelopmental Outcomes ◽  
Fetal Origins ◽  
Behavior Development ◽  
Increased Risk ◽  
Health And Disease ◽  
Brain And Behavior ◽  
And Behavior ◽  
The Impact

The developmental origins of health and disease hypothesis applied to neurodevelopmental outcomes asserts that the fetal origins of future development are relevant to mental health. There is a third pathway for the familial inheritance of risk for psychiatric illness beyond shared genes and the quality of parental care: the impact of pregnant women's distress—defined broadly to include perceived stress, life events, depression, and anxiety—on fetal and infant brain–behavior development. We discuss epidemiological and observational clinical data demonstrating that maternal distress is associated with children's increased risk for psychopathology: For example, high maternal anxiety is associated with a twofold increase in the risk of probable mental disorder in children. We review several biological systems hypothesized to be mechanisms by which maternal distress affects fetal and child brain and behavior development, as well as the clinical implications of studies of the developmental origins of health and disease that focus on maternal distress. Development and parenting begin before birth.

scholarly journals Glucocorticoid receptor action in metabolic and neuronal function

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 1208 ◽  
Author(s):  
Michael J. Garabedian ◽  
Charles A. Harris ◽  
Freddy Jeanneteau
Keyword(s):  
Gene Expression ◽  
Glucocorticoid Receptor ◽  
Metabolic Diseases ◽  
Cell Types ◽  
Health And Disease ◽  
And Behavior ◽  
External Signals ◽  
The Brain

Glucocorticoids via the glucocorticoid receptor (GR) have effects on a variety of cell types, eliciting important physiological responses via changes in gene expression and signaling. Although decades of research have illuminated the mechanism of how this important steroid receptor controls gene expression using in vitro and cell culture–based approaches, how GR responds to changes in external signals in vivo under normal and pathological conditions remains elusive. The goal of this review is to highlight recent work on GR action in fat cells and liver to affect metabolism in vivo and the role GR ligands and receptor phosphorylation play in calibrating signaling outputs by GR in the brain in health and disease. We also suggest that both the brain and fat tissue communicate to affect physiology and behavior and that understanding this “brain-fat axis” will enable a more complete understanding of metabolic diseases and inform new ways to target them.

Reprint of: Effects of BDNF polymorphisms on brain function and behavior in health and disease

2012 ◽  
Vol 88 (5) ◽  
pp. 406-417 ◽  
Author(s):  
Chen-Jee Hong ◽  
Ying-Jay Liou ◽  
Shih-Jen Tsai
Keyword(s):  
Brain Function ◽  
Health And Disease ◽  
And Behavior

scholarly journals Is Resting State Functional MRI Effective Connectivity in Movement Disorders Helpful? A Focused Review Across Lifespan and Disease

2021 ◽  
Author(s):  
Bethany L. Sussman ◽  
Sarah N. Wyckoff ◽  
Jennifer Heim ◽  
Angus A. Wilfong ◽  
David Adelson ◽  
...  
Keyword(s):  
Movement Disorder ◽  
Movement Disorders ◽  
Resting State ◽  
Effective Connectivity ◽  
Resting State Fmri ◽  
Motor Network ◽  
Adults And Children ◽  
Health And Disease ◽  
Human Motor ◽  
And Behavior

AbstractIn the evolving modern era of neuromodulation for movement disorders in adults and children, much progress has been made recently characterizing the human motor network (MN) with potentially important treatment implications. Herein is a focused review of relevant resting state fMRI functional and effective connectivity of the human motor network across the lifespan in health and disease. The goal is to examine how the transition from static functional to dynamic effective connectivity may be especially informative of network-targeted movement disorder therapies, with hopeful implications for children.Impact StatementWhile functional connectivity has elucidated much MN properties with relation to age, disease, and behavior, effective connectivity has been shown to be useful in MN-informed therapies in adults. Thus, effective connectivity may have potential to impact childhood movement disorder therapies, given the lower to no patient demand.

scholarly journals Features of psychological mechanisms of self-regulation among students of different professional orientation

2020 ◽  
Vol 210 ◽  
pp. 19002
Author(s):  
Anna Kukulyar ◽  
Anastasia Kolenova ◽  
Yulia Karagodskaya ◽  
Anna Kryuchkova ◽  
Viktoria Korhova
Keyword(s):  
Empirical Study ◽  
Self Regulation ◽  
Professional Community ◽  
Diagnostic Methods ◽  
Practical Significance ◽  
Professional Orientation ◽  
Knowledge And Skills ◽  
Psychological Mechanisms ◽  
Regulation Mechanisms

The modern social environment in general, and educational in particular, imposes a number of requirements on the personality of the student as a future representative of the professional community. This manifests itself in the need to master professional knowledge and skills in the conditions of constantly changing requirements, planning their activities for the short and / or long term, as well as multiple flexibility of behavior. The object of the research was 100 students of various faculties of DSTU (technical and humanitarian orientation). In the course of the empirical study, we used diagnostic methods for identifying self-regulation mechanisms in the student environment "USK" by J. Rotter; a questionnaire for the diagnosis of individual stylistic features of self-regulation (V. I. Morosanova), the methodology “Research of volitional self-regulation” (A. V. Zverkova, E. V. Eydman). The practical significance of the work lies in the subsequent use of the data obtained in the framework of psychocorrectional work with students of the organization of secondary vocational education.

scholarly journals Methodology of expert evaluation of effectiveness of methods of organizational diagnostics

2017 ◽  
pp. 38-43
Author(s):  
T. V. CHIBIKOVA
Keyword(s):  
Standard Deviation ◽  
Coefficient Of Variation ◽  
Random Variable ◽  
Diagnostic Methods ◽  
Practical Significance ◽  
Expert Evaluation ◽  
Practical Application ◽  
Actual Problem ◽  
Survey Results ◽  
Statistical Indicators

The article is devoted to the actual problem of assessing the effectiveness of consulting methods. Management consulting is a developing sphere of human activity. The technique of an estimation of efficiency of methods of organizational diagnostics is offered. The research was based on the problem of assessing the effectiveness of diagnostic methods in consulting using only economic indicators. According to the methodology, during the evaluation, the effectiveness of methods is is assessed in the light of costs and results, both should be similarly broken down into a number of elements. These elements were to be evaluated by experts. To confirm the validity of the results obtained, statistical indicators are used: variance of a random variable, standard deviation and coefficient of variation, which confirm (or disprove) the results of an expert poll.To approbate the methodology, a survey of experts elected among employees of consulting companies in Omsk was conducted. The survey data was analyzed. Based on the results of the analysis, the validity of the obtained survey results and the possibility of their practical application was concluded. The practical significance of the study is that it is possible to apply the methodology of interviewing experts in practice. The purpose of such surveys will be a regular reassessment and identification of the need for specific consulting methods for certain methods of organizational diagnostics.

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