scholarly journals Efektivitas Ekstrak Daun Sirsak (Annona Muricata) Dan Latihan Fisik Serta Kombinasi Terhadap Kadar Malondialdehid Hepar Pada Model Tikus Hiperkolesterolemia-Diabetes

2020 ◽  
Vol 13 (1) ◽  
pp. 11-18
Author(s):  
Retno Yulianti
Keyword(s):  
Vitamin E ◽  
Annona Muricata ◽  
Post Hoc ◽  
One Way Anova

Diabetes menyebabkan kerusakan jaringan akibat hiperglikemia dan hiperkolesterolemia. Stres oksidatif dapat menyebabkan peroksidasi lipid yang dinilai melalui kadar malondialdehid. Modifikasi gaya hidup dengan latihan fisik meningkatkan ambilan glukosa dan menurunkan profil lipid. Ekstrak daun sirsak berpotensi menurunkan kadar Malondialdehyde. Penelitian ini bertujuan untuk mengetahui efek ekstrak daun sirsak dan latihan fisik serta kombinasi terhadap kadar Malondialdehid hepar tikus diabetik. Tiga puluh ekor tikus putih jantan galur Wistar, dikelompokkan menjadi enam kelompok yaitu: pakan standar dan aquades (K1), pakan tinggi lemak dan metformin 45mg/kgBB/hari (K2), pakan tinggi lemak dan vitamin E 150 IU/kgBB/hari (K3), pakan tinggi lemak dan latihan fisik sedang 20 m/menit (K4), pakan tinggi lemak dan ekstrak daun sirsak 150 mg/kgBB/hari (K5), pakan tinggi lemak dan kombinasi (K6). Ekstrak daun sirsak diberikan selama 21 hari setelah diinduksi aloksan dan pakan tinggi lemak selama 5 minggu. Analisis data menggunakan uji One Way ANOVA dan dilanjutkan dengan uji Post Hoc LSD. Pada kelompok K6 mampu menurunkan gula darah puasa 70.97% dan kolesterol 62.47% dan bermakna dalam menurunkan kadar Malondialdehyde 0,9 µMol. Kesimpulan adalah kombinasi ekstrak daun sirsak dan latihan fisik memiliki kemampuan menurunkan kadar Malondialdehyde jaringan hepar.

scholarly journals Efektivitas Ekstrak Daun Sirsak (Annona Muricata) Terhadap Kadar Malondialdehid Hepar Tikus Diabetik Setelah Diinduksi Aloksan

2020 ◽  
Vol 6 (2) ◽  
pp. 65-71
Author(s):  
Retno` Yulianti ◽  
Lina Adilla ◽  
Imam Prabowo
Keyword(s):  
Reactive Oxygen Species ◽  
Vitamin E ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Annona Muricata ◽  
Post Hoc ◽  
One Way Anova

Hiperglikemik yang tidak terkontrol memicu pembentukan reactive oxygen species (ROS) yang berlebih di dalam tubuh sehingga menyebabkan peroksidasi lemak pada membran sel. Regulasi jumlah ROS dapat diukur melalui kadar malondealdehid. Tujuan penelitian ini untuk mengetahui efektivitas ekstrak daun sirsak (EDS) terhadap kadar Malondialdehid hepar tikus diabetik. Sebanyak 30 ekor tikus putih jantan galur Wistar dikelompokkan menjadi (K1) pakan standar dan aquades, (K2) pakan tinggi lemak dan vitamin E α-tokoferol 150 IU/kgBB/hari, dan kelompok yang menggunakan pakan tinggi lemak dengan tiga dosis EDS 75 mg/kgBB/hari (K3), 150 mg/kgBB/hari (K4), dan 300 mg/kgBB/hari (K5). Ekstrak daun sirsak diberikan selama 21 hari setelah hari ke-3 induksi aloksan dan pakan tinggi lemak selama 5 minggu. Analisis data menggunakan uji One Way ANOVA dan dilanjutkan dengan uji Post Hoc Least Significant Differences. Hasil penelitian menunjukkan bahwa pada kelompok perlakuan K4 dibandingkan kelompok perlakuan K3, K5 dan kelompok kontrol K2 menunjukkan penurunan kadar gula darah puasa (131,1 mg/dL) dan  kadar Malondialdehid (0.35796 nm/mL) yang lebih baik. Kesimpulan penelitian ini bahwa ekstrak daun sirsak efektivitas menurunkan kadar Malondialdehid dengan dosis optimal 150 mg/kgBB/hari.

scholarly journals PENGARUH PEMBERIAN VITAMIN C, VITAMIN E, DAN KROMIUM (CR3+) TERHADAP KADAR INSULIN TIKUS WISTAR YANG DIINDUKSI ALOKSAN

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Anugrah Linda Mutiarani
Keyword(s):  
Vitamin E ◽  
Vitamin C ◽  
Statistical Tests ◽  
Normal Diet ◽  
Control Group ◽  
Insulin Levels ◽  
Experimental Laboratory ◽  
Group 3 ◽  
Post Hoc ◽  
One Way Anova

Objective: To analyze the effect of vitamin C, vitamin E, and chromium (Cr3+) on insulin levels Wistar ratswere induced alloxan.Materials and Methods: This study is an experimental laboratory. Using rats typeWistar strain Rattus novergicus for 6 weeks with a number of 20 head. The independent variables consist of 5treatment groups namely normal diet, normal diet + 1 g/hr chromium, normal diet + 2 mg/day of vitamin C,normal diet + 0.5 mg/day of vitamin E, normal diet + 1 g/hr chromium + 2 mg/day of vitamin C + 0.5mg/day of vitamin E. The dependent variable is the level of insulin. To know the differences of eachtreatment used statistical tests One Way ANOVA, followed by Tukey HSD Post Hoc test withp<0.05.Results: There were significant differences in insulin levels (p<0.05) in the control group, 1, 2, and 4.But in the control group and the group 3 there are no significant differences in insulin levels (p=0.145).Conclusion: Delivery of chromium (treatment 1), vitamin C (treatment 2), and a mixture of chromium,vitamin C, vitamin E (treatment 4) effect on insulin levels, while administration of vitamin E (treatment 3)alone had no effect on insulin levels

scholarly journals Proximate Composition and Micronutrient Contents of Callianassa turnerana from the Wouri Estuary, Cameroon

2018 ◽  
Vol 8 (1) ◽  
pp. 32
Author(s):  
Jean Michel Njinkoué ◽  
Rodrigue Foumedzo ◽  
Marlyse Solange Leng ◽  
Justin Djimbie Djopnang ◽  
Adélaïde Démassé Mawamba ◽  
...  
Keyword(s):  
Vitamin E ◽  
Proximate Composition ◽  
Good Source ◽  
Total Carotenoids ◽  
Lipid Contents ◽  
Major Nutrients ◽  
Post Hoc ◽  
Edible Parts ◽  
One Way Anova ◽  
Improve Health

Callianassa turnerana, called Cameroon ghost shrimps is shrimp with a great sociocultural interest in Cameroon. This study assessed proximate composition and micronutrients contents of Callianassa turnerana from the Wouri estuary in Cameroon. Adult shrimps were collected. The proximate composition, mineral, carotenoids and vitamin E contents were determined in edible parts (male and female) and in eggs of C. turnerana using official analytical methods. One way ANOVA and Fisher&rsquo;s post hoc PLS test was used to analyze the data. The moisture content were 66&plusmn;1.5%, 62 &plusmn;2.85%, 49.0 &plusmn;1.60% in edible parts of male, female and in eggs respectively. Protein contents were high in all the samples ranging from 10.49&plusmn;0.92% in male edible parts to 30.06&plusmn;0.89% in eggs. Lipid contents were more than 12% in all samples. Carbohydrate were absent in eggs while the contents were 9.92&plusmn;0.99% in male and 12.23&plusmn;0.81% in female edible parts. C. turnerana is a good source of minerals. Sodium (0.983&plusmn;0.001%- 1.656&plusmn;0.005%) and Phosphorus (0.974&plusmn;0.002%-1.321&plusmn;0.002%) were the main macro elements in all samples. Zn was the major microelement in edible parts with the value ranged from 6.43&plusmn;0.49mg/100g (male) to 7.62&plusmn;0.35mg/100g (female) while Cu was the major microelement (10.15&plusmn;3.57mg/100g) in eggs. High levels of total carotenoids (7.9-15.45&micro;g/g) and vitamin E (12.53-24.03&micro;g/g) were recorded. The main carotenoids were &beta;-caroten (0.637-1.337&micro;g/g) followed by &alpha;-caroten (0.216-0.437&micro;g/g). C. turnerana is a good source of many major nutrients and micronutrients and could be used to combat malnutrition and improve health.

scholarly journals The effect of ethanol extract of soursop leaf (Annona muricata L.) on Adhesion of Streptococcus mutans ATCC 35668 to hydroxyapatite discs

2018 ◽  
Vol 4 (1) ◽  
pp. 22
Author(s):  
Friska Ani Rahman ◽  
Tetiana Haniastuti ◽  
Trianna Wahyu Utami
Keyword(s):  
Streptococcus Mutans ◽  
Dental Plaque ◽  
Ethanol Extract ◽  
Positive Control ◽  
Tooth Surface ◽  
Annona Muricata ◽  
Dental Hard Tissues ◽  
Attachment Mechanism ◽  
Post Hoc ◽  
One Way Anova

The demineralization of dental hard tissues can be caused by dental plaque. Dental plaque contains various components, especially bacteria attached to the extracellular matrix. Streptococcus mutans (S. mutans) has extracellular glucan as adhesin that is important in the attachment mechanism of tooth surface. The natural substance can be used for preventing plaque formation by inhibiting the attachment of S. mutans. Soursop plant has been used in treating various diseases. The leaves of the soursop (Annona muricata L.) are used as a material to inhibit potential attachment of bacteria S. mutans. Common surfaces that is used in adhesion testing is hydroxyapatite (HA). The aim of this study was to evaluate the effect of ethanol extract of soursop leaf (EESL) on the adhesion of S. mutans ATCC 35668 to HA discs. Soursop leaves were extracted by the maceration method using 70% ethanol. The experiment was carried out by analyzing the inhibition adhesion of S. mutans ATCC 35668 on HA discs after incubation with different concentrations of soursop leaf extract. The concentrations of extract tested were: 150; 125; 100; 75; and 50 mg/ml. Chlorhexidine 0.2% was used as a positive control while DMSO 5% was used a negative one. Data were evaluated by One Way Anova. This study statistically showed significant differences of S. mutans colony count between groups (p<0.05).The results of a post hoc Dunnett T3 test showed that the 2 highest concentrations of extract (125 and 150 mg/ml) reduced S. mutans adhesion on HA discs.The obtained results showed that ethanol extract of soursop leave inhibits the adherence of S. mutans to the HA disc.

scholarly journals PENGARUH PEMBERIAN VITAMIN C DAN E TERHADAP JUMLAH SEL SPERMATOGONIA YANG DIPAPAR RADIASI SINAR X (Studi Eksperimental pada Mencit (Mus Muculus) Galur Balb/C)

2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Mochammad Soffan ◽  
T M Rafsanjani
Keyword(s):  
Vitamin E ◽  
Vitamin C ◽  
Mus Musculus ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
Post Hoc ◽  
One Way Anova

<p>Radiasi sinar X merupakan salah satu radiasi pengion yang menyebabkan terbentuknya radikal bebas sehingga merusak sel spermatogonia. Penggunaan vitamin C dan E sebagai antioksidan untuk melindungi sel tubuh. Penelitian ini bertujuan mengetahui pengaruh pemberian vitamin C dan E terhadap jumlah sel spermatogonia yang dipapar radiasi sinar X. Metode penelitian eksperimental dengan rancangan <em>post test only control group design</em> pada 35 ekor mencit (<em>Mus musculus</em>) dibagi menjadi 5 kelompok secara acak yaitu KP tanpa paparan radiasi dan pemberian vitamin, KN dengan paparan radiasi sinar X 25 mGy/hari tanpa pemberian vitamin, KP 1 diberikan vitamin C 0,26 mg/hari, KP 2 diberikan vitamin E 0,208 mg/hari, KP 3 diberikan kombinasi vitamin C 0,26 mg/hari dan vitamin E 0,208 mg/hari setiap sebelum pemaparan radiasi sinar X 25 mGy/hari selama 4 hari dengan waktu penelitian 21 hari. Pada hari ke 22 sampel diterminasi diamati melalui mikroskop. Jumlah sel spermatogonia dianalisis <em>One Way Anova </em>kemudian uji <em>post Hoc LSD. </em>Hasil rerata jumlah spermatogonia pada KP, KN, KP1, KP2 dan KP3 yaitu 24,24; 13,28; 19,36; 19,60 dan 23,32. Hasil uji <em>One Way Anova </em>diperoleh nilai p sebesar 0,000 (p&lt;0,05) artinya terdapat perbedaan rerata jumlah sel spermatogonia yang bermakna antara kelima kelompok. Hasil uji <em>post Hoc LSD</em> menunjukkan perbedaan rerata sel spermatogonia antar dua kelompok ditunjukkan oleh hampir semua pasangan kelompok (p&lt;0,05); kecuali untuk perbandingan rerata sel spermatogonia antara KP1 dan KP2 (p&gt;0,05). Terdapat pengaruh pemberian vitamin C dan E terhadap jumlah sel spermatogonia mencit yang dipapar radiasi sinar X.</p>

scholarly journals Depth-Related Curing Potential of Ormocer- and Dimethacrylate-Based Bulk-Fill Composites

Materials ◽  
2021 ◽  
Vol 14 (22) ◽  
pp. 6753
Author(s):  
Ramona S. Oltramare ◽  
Reto Odermatt ◽  
Phoebe Burrer ◽  
Thomas Attin ◽  
Tobias T. Tauböck
Keyword(s):  
Double Bond ◽  
Repeated Measures ◽  
In Vitro Study ◽  
High Viscosity ◽  
Degree Of Conversion ◽  
Double Bond Conversion ◽  
Nanohybrid Composite ◽  
Post Hoc ◽  
One Way Anova

The aim of this in vitro study was to investigate the degree of C=C double bond conversion of high-viscosity dimethacrylate- or ormocer-based bulk-fill composites as a function of measurement depth. Four bulk-fill composites (Tetric EvoCeram Bulk Fill, x-tra fil, SonicFill, and Bulk Ormocer) and the conventional nanohybrid composite Tetric EvoCeram were applied in standardized Class II cavities (n = 6 per group) and photoactivated for 20 s at 1350 mW/cm2. The degree of conversion of the composites was assessed using Fourier-transform infrared spectroscopy at seven measurement depths (0.15, 1, 2, 3, 4, 5, 6 mm). Data were analyzed using repeated measures ANOVA and one-way ANOVA with Bonferroni post-hoc tests (α = 0.05). The investigated bulk-fill composites showed at least 80% of their maximum degree of conversion (80% DCmax) up to a measuring depth of at least 4 mm. Tetric EvoCeram Bulk Fill and Bulk Ormocer achieved more than 80% DCmax up to a measuring depth of 5 mm, x-tra fil up to 6 mm. The conventional nanohybrid composite Tetric EvoCeram achieved more than 80% DCmax up to 3 mm. In contrast to the conventional composite, the investigated ormocer- and dimethacrylate-based bulk-fill composites can be photo-polymerized in thick layers of up to at least 4 mm with regard to their degree of C=C double bond conversion.

scholarly journals Avaliação e proposta de monitoramento do estado de conservação de ambiente recifal costeiro do Estado da Paraíba, Brasil: contribuições para gestão ambiental

2018 ◽  
Vol 5 (10) ◽  
pp. 949-967 ◽  
Author(s):  
Daniel Silva Lula Leite ◽  
George Emmanuel Cavalcanti de Miranda
Keyword(s):  
Gelidiella Acerosa ◽  
Post Hoc ◽  
Canistrocarpus Cervicornis ◽  
One Way Anova

A urbanização nas zonas costeiras torna necessário avaliar o impacto antrópico sobre os ecossistemas associados. O objetivo deste trabalho foi analisar temporalmente a dinâmica de populações de macroalgas com potencial bioindicador, estabelecendo-as como ferramenta para avaliação da saúde ambiental. Foi amostrado o ambiente recifal intertidal da Praia de Formosa, no Município de Cabedelo, Estado da Paraíba, Nordeste do Brasil, durante intervalos trimestrais de agosto/2013 a novembro/2014. A variação temporal da frequência de ocorrência (F') das populações macrofitobênticas foi avaliada pela análise de variância (One-Way Anova) com teste Post-Hoc de Tukey. A influência das variáveis ambientais sobre F’ foi avaliada pela Correlação Linear de Pearson e pela PERMANOVA. A análise da qualidade ambiental e a proposta de biomonitoramento basearam-se no Grupo 1, formado por espécies perenes e/ou raras com maiores valores ao longo do Componente Principal 1 (CP1) da Análise de Componentes Principais (ACP), e Grupo 2, formado por espécies com comportamento errático com menores valores ao longo do CP1 da ACP. Foram encontradas 33 espécies macrofitobênticas. A frequência de ocorrência apresentou variação temporal, porém não influenciada pelo conjunto de variáveis ambientais. Phyllodictyon anastomosans, Gelidiella acerosa e Gelidium corneum compuseram o Grupo 1, com Dictyopteris delicatula, Canistrocarpus cervicornis e Hypnea spinella formando o Grupo 2. O Grupo 2 apresentou correlação positiva com a temperatura, alcançando as máximas frequências nos períodos mais quentes, mas esse fator isolado não é capaz de explicar a distribuição errática das espécies. A ocorrência de espécies bioindicadoras de eutrofização foi considerada natural, fato que, aliado à alta frequência de espécies bioindicadoras de qualidade ambiental, sugerem que o Recife de Formosa não sofre impactos antrópicos significativos. O desaparecimento de espécies perenes ou crescimento populacional significativo de espécie rara (Grupo 1), bem como a fuga do padrão temporal de frequência ou dominância do recife pelas espécies do Grupo 2, são indícios da ocorrência de impactos. Este trabalho fornece à gestão do Recife de Formosa uma eficiente ferramenta para avaliação do impacto urbano sobre a comunidade macrofitobêntica.

scholarly journals The Robusta coffee grounds residues to adsorb the heavy metal Lead (Pb) in the water

2018 ◽  
Author(s):  
Anita Dewi Moelyaningrum ◽  
Khoirul Ngibad ◽  
S.Pd Lilla Puji Lestari ◽  
Dessy Agustina Sari ◽  
Cahya Fajar Budi Hartanto ◽  
...  
Keyword(s):  
High Carbon ◽  
Control Groups ◽  
Robusta Coffee ◽  
Randomized Design ◽  
Coffee Grounds ◽  
Coffee Ground ◽  
Completely Randomized Design ◽  
Post Hoc ◽  
One Way Anova ◽  
Ks Test

This paper has been published in IOP Conf. Series: Journal of Physics: Conf. Ser1i2e3s415161748(9200‘1’8“)”012058 Lead (Pb) were toxic. Lead found in pipes, batteries, paint, dyes ceramic glaze, gasoline, and final waste disposal. The robusta coffee grouds residues had high carbon, nitrogen etc which can adsorb heavy metal.The purpose of this study is to analyze the robusta coffee grounds residues to adsorb the Pb in the water. The method of this research is a True Experimental using completely randomized design (CRD) method. There were control groups (C) and three treatments groups (T1; T2;T3; 5gram/ litre; 8gram/ litre; 10gram/ litre) with six repetitions. The robusta coffee ground residues were contacted for 2 hours.Total samples were24 samples which analyzed each parameter of the Pb with Atomic Adsorption Spectophotometry Analysis. The results showed that the more coffee ground residues that are exposed, increasingly turbid. The KS test showed that data were a normal distribution (sig=0,324). One way ANOVA test; Turkey post Hoc showed that there was sig difference between the control and treatment (F=4,326, Sig= 0,017). There were sig difference between control and treatment 2 and 3 (Sig=0,019; Sig=0,038). Robusta coffee grounds residues can reuse to adsorb the Pb pollution in the water. It can be a solution for treating the lead pollution in the water because of it easy to the application.

scholarly journals Selected Goal – Scoring Characteristics in the National Hockey League

2021 ◽  
Vol 61 (2) ◽  
pp. 228-237
Author(s):  
Silvio Parničan ◽  
Pavol Peráček ◽  
Igor Tóth
Keyword(s):  
Ice Hockey ◽  
National Hockey League ◽  
Training Process ◽  
Significance Level ◽  
Game Situation ◽  
Post Hoc ◽  
Number Of Passes ◽  
Determining Factor ◽  
One Way Anova ◽  
Location Zone

Summary The variables impacting the efficiency of the offensive phase of the game in ice hockey may be determining factor for both the training process and game strategies. The research aimed to acquire and expand the knowledge about selected goal-scoring characteristics in the National Hockey League. A total of 511 even-strength goals were recorded in 129 randomly selected games in a regular-season 2020/2021 by indirect observation. Goals were differentiated by selected variable dimensions: location of the offensive team’s puck possession gain before scoring a goal, game situation preceding a goal, and the number of passes of the offensive team preceding a goal. Data were analyzed by performing a one–way ANOVA. Post hoc multiple comparisons were performed using the Tukey HSD test. The significance level of p ≤ 0.05 was used. Significant differences were found within all variable dimensions (p= 0.00001). In terms of the puck possession gain location, zone 1 (along the boards in the offensive zone) was the zone with the significantly highest mean score (p= 0.00305). Offensive zone play was significantly the game situation preceding most of the goals (p= 0.00000). The interval of the passes that preceded most of the recorded goals was the interval of 1 – 2 passes (p= 0.00000). Acquired results point out the dominance of particular variables and may help coaches to determine the content of the training process and game strategies. Based on the assumption of the realization of similar research in different environments in terms of the quality and age category, if the analogy would be found between the results of the present study and the results of potential studies, we can state the trends applicable to youth training.

scholarly journals CREATININE AND CREATINE KINASE RATIO IN BLOOD OF DIFFERENT BODY TYPES - A NEW APPROACH.

2021 ◽  
Vol 4 (2) ◽  
Author(s):  
Anupam Bandyopadhyay ◽  
Pritha Chatterjee
Keyword(s):  
Creatine Kinase ◽  
Creatinine Level ◽  
Creatine Kinase Level ◽  
Fat Content ◽  
Standard Laboratory ◽  
Laboratory Methods ◽  
New Approach ◽  
Modifiable Factors ◽  
Post Hoc ◽  
One Way Anova

Purpose: The inconsistencies and variations of creatine kinase level due to modifiable and non-modifiable factors were the basis of this study. The aim was to find out the relationships between creatinine and creatine kinase in the blood of somatotypes.    Methods: The 122 males, aged 10 to 20 years, were classified according to their somatotypes. Somatotypes were measured by the ISAK method. By standard laboratory methods, creatinine and creatine kinase estimate. The IBM SPSS version 24 is used for calculation. One way ANOVA followed by post hoc tests was performed to compare the variables among the three groups (p<0.05).   Results: Creatinine level in the blood insignificantly deferred among the three somatotypes. The significant differences (p<0.05) were found in creatine kinase level in the blood and creatinine/creatine kinase ratio among the three dominant Somatotypes. Creatine Kinase was significantly higher in Ectomorphs (212 U/L) than Endomorphs. Ectomorphs and mesomorphs have crossed normal creatine kinase levels (35 -175 U/L). The creatinine/creatine kinase ratio was found highest in endomorphs and lowest in the ectomorphs and significantly differed in three Somatotypes.   Conclusion: Creatinine production remains the same, indicating production of Creatinine is independent of specific body types. A significant higher Creatine Kinase level in Ectomorphs over Endomorphs showed fat content was not associated with it. Significant differences in Creatinine / Creatine Kinase ratio among Somatotypes suggested its relevance between cellular and morphological relationships and might uses as biomarkers. 

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