scholarly journals About help from physicists in fighting sars-cov-19 and its mutations

2021 ◽  
Vol 6 ◽  

Annotation: Currently, the SARS-CoV-19 (COVID-19) coronavirus pandemic is the main threat to all of humanity. This threat is constantly growing as new and more aggressive mutations emerge. The main ways of fighting viruses are currently recognized: vaccination, disinfection, quartzization and isolation. However, they all have their own advantages and disadvantages. The analysis of these shortcomings and the search for ways to eliminate them is an important and urgent task, which is the main goal of the work performed. Methods: a critical analysis of the emerging problems of traditional ways and methods of biophysical impact on viruses. Scientific novelty lies in the rationale for a new biophysical way to combat COVID-19 and in setting the tasks that are required to he solve. Results of work: Vaccination is considered to be the most effective method of combating COVID-19. However, it has weakened, but not prevented, the spread of viruses, as it acts in pursuit of his new mutations. This leads to local periods of lack of immune protection, in which the only way is used - the introduction of restrictions on the lifestyle and activities of people, up to rigid isolation. Other traditional ways to combat COVID-19 involve disinfection and quartzing. However, the entry of an infected person into this area after they have been carried out nullifies their results and leads to the need for new disinfection. Therefore, all traditional methods are limited by the time and conditions of their implementation and the duration of effective action, and most importantly, they require a large investment of time, intellectual, technical, economic and labor resources to achieve the desired result (especially the creation of vaccines). Since all of them did not solve the problem of eliminating the pandemic and destroying viruses, but only slowed down their spread, it is proposed to discuss another way-their destruction by the method of resonant oscillations (vibrations) created by electromagnetic fields from external sources. On the basis of this, the 1st task was formulated for further work: search for the resonant frequency range destroying viruses, and the 2nd task the search for the frequency range that activates the virus, in order to exclude its appearance in the development of new electronic systems and technical devices. The need for a fundamental solution to these problems at the level of state and non-state health organizations with the wide involvement of physicists and biophysicists is brought up for discussion by the scientific community of all countries of the world. Such a path could create the basis for their quick and effective solution.

2013 ◽  
Vol 364 ◽  
pp. 253-256 ◽  
Author(s):  
Qi Zhang ◽  
Ying Jun Li ◽  
Ru Jian Ma ◽  
Xiu Hua Men

In order to solve the forming defects in the steel ball cold heading process, a novel force sensor which chooses the PVDF piezoelectric films as force-sensing elements is designed. The advantages and disadvantages of piezoelectric force sensor on measurement of the cold heading force are compared with existing force sensors. By using FEM, sensor’s linearity and the structure size are analyzed. Compared with the traditional sensor, this structure is more reasonable. The presented PVDF piezoelectric force sensor has wide frequency range, good dynamic performance, and can realize dynamic measurement.


2001 ◽  
pp. 117-127
Author(s):  
Svetlana Demchenko ◽  

The information base of the study was the works of economists in the field of approaches to assessing the effectiveness of worker’s work. The article is devoted to the development of an algorithm for evaluating labor efficiency, taking into account the improved methodology. The hypothesis of the study is the assumption of increasing the influence of the concept of sustainable economic development on the choice of methods for evaluating the effectiveness of labor resources. Within the framework of this study, the authors consider various concepts for the study of labor efficiency, highlight the advantages and disadvantages of existing approaches and offer their own concept of evaluating labor efficiency from the point of view of the concept of sustainable development. The approbation of the author's methodology is presented on the example of a specific company.


Pharmaceutics ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 125 ◽  
Author(s):  
Courtney van Ballegooie ◽  
Alice Man ◽  
Mi Win ◽  
Donald Yapp

This review explores the use of energy sources, including ultrasound, magnetic fields, and external beam radiation, to trigger the delivery of drugs from liposomes in a tumor in a spatially-specific manner. Each section explores the mechanism(s) of drug release that can be achieved using liposomes in conjunction with the external trigger. Subsequently, the treatment’s formulation factors are discussed, highlighting the parameters of both the therapy and the medical device. Additionally, the pre-clinical and clinical trials of each triggered release method are explored. Lastly, the advantages and disadvantages, as well as the feasibility and future outlook of each triggered release method, are discussed.


2014 ◽  
Vol 605 ◽  
pp. 577-580 ◽  
Author(s):  
Tibor Izak ◽  
Katarína Novotná ◽  
Ivana Kopová ◽  
Lucie Bačáková ◽  
Marián Varga ◽  
...  

In this paper we introduce fully optically transparent impedance biosensors based on intrinsic nanocrystalline diamond (NCD) films deposited on glass substrate. Prepared sensors have an interdigital electrode (IDE) structures realized by local hydrogen and oxygen termination of diamond surface, which mean in-plane configuration of active sensor area. Sensors were tested by real time monitoring of human osteoblast-like MG 63 cells in wide frequency range from 10 Hz to 100 kHz for several days. Two different measurement setups were used and compared regarding to their advantages and disadvantages. Proof of concept of diamond-based impedance sensor is showed, i.e. time dependence and frequency dependence (Nyquist plots) of absolute impedance.


2012 ◽  
Vol 610-613 ◽  
pp. 2488-2492
Author(s):  
Pei Feng Liu ◽  
Tao Lv ◽  
Qing Hua Bu

The application of the linear motor is a hot topic in current researching. The dynamic thrust testing is not also an important indicator in the study of linear motor, but also one of the difficulties in the study of linear motor characteristics. The LSM-SA dynamic thrust testing device was researched in the gate of river and main canal. According to compare with the traditional dynamic thrust test, its principle, advantages and disadvantages was illustrated. Some improvements were further made. Meanwhile, the variation of the improved cogging force was analyzed, the curve of the cogging force was made and the LSM-SA testing equipment was designed. Finally, the accuracy of the equipment was verified. It can directly conduct a test of the dynamic thrust. Nowadays, flood protection and disaster prevention has become an urgent task to solve, it is directly related to the country’s economy and people’s lives. The dynamic thrust to control the gate of the river and the main canal was used to prevent disaster. Therefore, the determination of the dynamic thrust becomes particularly important. In order to achieve the system to operate efficiently and accurately, the size of the dynamic thrust must be accurately determined. The device could achieve high accuracy direct drive to ensure the safe and effective operation of the gate of the river and the main canal, develop the water conservancy.


2021 ◽  
Vol 129 (1) ◽  
pp. 100
Author(s):  
А.Н. Cпицын ◽  
Д.В. Уткин ◽  
О.С. Кузнецов ◽  
П.С. Ерохин ◽  
Н.А. Осина ◽  
...  

The study and identification of microorganisms plays asignificant role in the diagnosis of infectious diseases, so an important and urgent task is to introduce new technologies aimed at improving research. Obtaining quantitative and qualitative information about bacteria with high speed, specificity, detection sensitivity, low cost and ease of analysis is particularly substantial. This review examines the use of modern diagnostic technologies that allow for the study of biological systems with a high degree of analytical reliability. Technologies of Raman spectroscopy, FTIR spectroscopy, and surface plasmon resonance used in modern biosensors have proven to be significant and promising research tools. The main advantages and disadvantages of the methods used, as well as the results of their practical use, are indicated. A significant interest induce modern approaches in studying of microorganisms with the use of genetic protein dye – GFP and with applaying nanomaterials – theranostics.


2019 ◽  
pp. 75-80
Author(s):  
V. P. Razinkin ◽  
K. Ya. Aubakirov ◽  
T. G. Serikov

Currently, modern telecommunication and radio-electronic systems widely use wireless information transmission technologies over the radio channel. Therefore, an urgent task is to ensure electromagnetic compatibility of a large number of simultaneously operating radio facilities using high-selective bandpass filters. This paper presents circuit solutions for microstrip filters using incomplete inclusion of loads and communication elements. This construction makes it possible to obtain additional attenuation poles in the near zone of the stop band, which frequencies are determined by the load inclusion factor. It is proposed to include a capacitor in the middle of the microstrip communication line to improve the selective properties. This made it possible to increase the order of the filter at constant dimensions. The frequency characteristics of a high-selective quasi-elliptic filter are given.


Author(s):  
Davide Castagnetti ◽  
Federico Dallari

Efficient conversion of ambient energy, being intrinsically variable and in the low frequency range is a fundamental issue for the development of self-powered electronic systems. Simple and reliable solutions are based on piezoelectric or electromagnetic transducers. This work presents an innovative electromagnetic vibration-based energy converter, relying on two counteracting slotted disc springs, which originate a low stiffness mechanical system under a given preload. The electromagnetic converter, involving cylindrical permanent magnets, features coils with a peculiar ‘8’ loop configuration, on opposite sides of the magnets. The prototype was built with commercial components and purposely developed parts, manufactured through rapid prototyping. The experimental validation highlights an excellent response, both in terms of the multi-frequency behaviour and with regard to the significant power output also at low input accelerations.


Radiotekhnika ◽  
2021 ◽  
pp. 77-87
Author(s):  
K.Yu. Shekhanin ◽  
S.V. Pshenichnaya ◽  
A.A. Kuznetsov

Several methods of technical steganography are currently known. Hiding information in a model in 3D printing, this industry of hiding information has certain advantages and disadvantages, namely: the relatively high cost of creating a hidden message and the difficulty in reading the information. The second area of technical steganography is related to network traffic. In this method, information can be hidden, for example, in the header fields of protocols, or, for example, the transmission of a hidden message by sending packets in a certain sequence. There are also methods of hiding information in the structure of the file system, but the known methods are either capable of hiding a small amount of information, or have an insufficient level of resistance to detection. Thus, an urgent task is to develop a method for hiding information, which is able to hide more information and has a higher level of resistance to detection, with a satisfactory level of computational complexity. This paper presents methods of technical steganography based on the structural features of file systems in storage media, in particular, hiding information in the FAT file system by mixing clusters of certain key files (cover files). Methods of hiding information in the structure of a clustered file system by mixing clusters of cover files require significant computational resources. In this paper, research has been carried out on methods to increase computational efficiency in terms of the amount of required RAM, and the number of the required number of basic operations to hide a message.


Author(s):  
Celia María Calderón-Ramón ◽  
Héctor Daniel López-Calderón ◽  
Jesús Enríque Escalante-Martínez ◽  
María Inés Cruz-Orduña

The study of the biological tissue varies its behavior, in function of the frequency to which it is subjected. The functions of Cole-Cole, Debye and Lorentz are considered the most used to study the parameters of conductivity and permittivity of biological tissue such as: liver, stomach, gray matter, pancreas, blood, breast tissue to name a few. Depending on the frequency, there may be three different relaxation times. These depend on the nature and physical characteristics of the tissue and its effect in the presence of an electromagnetic signal. The Cole-Cole function is most appropriate when considering a study in the frequency domain, and the Debye function is established to perform the study in the time domain. It is of particular interest to make a comparison between the methods of Cole-Cole and Debye, to define the advantages and disadvantages of each of them. The Lorentz function is used for frequencies of the Tera-Hertz order. Comparative graphs are obtained between both for the biological tissues mentioned above. For each of them the electrical parameters are calculated in a frequency range between 100 Hz and 10 GHz.


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