Alterações no índice de massa corporal: Coorte em indivíduos em uso de dolutegravir

Goal: To assess body mass index (BMI) changes in people living with HIV (PLHIV) and using antiretroviral therapy (ART) with dolutegravir (DTG) and its associated factors. Methods: Retrospective and prospective cohorts of PLHIV who started ART with DTG or used DTG after changing the therapeutic regimen, from Belo Horizonte, between February/2017 and March/2020. Data were gathered from clinical records of the Drug Logistics and Laboratory Test Control Systems. BMI changes were analyzed in the following week intervals 1-24(t24), 25-48(t48), 49-72(t73), and 73-96(t96) using the Wilcoxon test and generalized estimation equation (GEE) model, at 5% significance level. Results: A total of 614 individuals were included and average was 38.4 years old. Most were men (85.5%) and 52.3% had started ART with DTG. These individuals, and the immunosuppressed ones, showed significant increases in BMI when compared to those who used DTG after switching therapeutics or the non-immunosuppressed ones (p-value <0.05). After 96 weeks, individuals starting ART with DTG had a mean increase in BMI of 1.02 Kg/m2, whereas those who used DTG after the therapeutic change had an increase of 0.56 Kg/m2 (p<0.05). DTG use length, ART type, immune status, baseline BMI, and age were associated (p<0.05) with BMI increases. Conclusions: We observed an increase in BMI both in individuals starting ART with DTG use and those using it after changing the therapeutic regimen.

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Effect of Antiretroviral Therapy With Tenofovir, Lamivudine And Dolutegravir On Respiratory And Peripheral Muscles Strengh In People Living With Hiv/Aids

10.21203/rs.2.15545/v1 ◽

2019 ◽

Author(s):

Renata de Oliveira Cardoso ◽

Paulo Sérgio Ramos de Araújo ◽

Juliana Barros Maranhão ◽

Marco Aurélio de Valois Correia Júnior ◽

Eduarda Lubambo Costa

Keyword(s):

Antiretroviral Therapy ◽

Muscle Weakness ◽

Handgrip Strength ◽

Laboratory Data ◽

Wilcoxon Test ◽

P Value ◽

People Living With Hiv ◽

Peripheral Muscle ◽

Living With Hiv ◽

Hiv Aids

Abstract Background Some antiretrovirals (ARVs) cause muscle toxicity and their use has been attributed to beginning of respiratory and peripheral muscle weakness in people living with HIV/AIDS (PLWHA) on treatment. Dolutegravir (DTG) has been adopted by Brazil as a first-line regimen with Tenofovir/Lamivudine (TDF/3TC) since 2017, with low toxicity profile. Due to the short use of this regimen, we have not found data in the literature regarding its effects in the respiratory and peripheral muscles in PLWHA. The aim of this study was to compare respiratory and peripheral muscle strength before and after start of this new combined ART (TDF/3TC/DTG).Methods Descriptive, longitudinal and prospective study, observational and analytical with 41 PLWHA evaluated before the initiation of antiretroviral therapy (ART) (T0) which of these, 28 were reevaluated after more than 50 days of treatment (T1).The assessments of maximum functional capacity (six-minute walk test distance), maximal inspiratory (MIP) and expiratory (MEP) pressures and handgrip strength (HGS) were performed using standardized methods. In addition, laboratory data (CD4, CD4/CD8 ratio and viral load-VL) were collected. Shapiro-Wilk test was applied for normality while Fisher's exact test and t-test or Wilcoxon test were used for comparisons of categorical and continuous variables, respectively. Pearson or Spearman correlations were used according to data normality and p-value < 0.05 were considered significant for all analyzes.Results The frequency of peripheral muscle weakness in patients evaluated at T0 was 97.6%, while 31.7% had inspiratory and / or expiratory muscle weakness. HGS was positively correlated with CD4 (p = 0.027) and negatively correlated with VL (p = 0.046). Both MIP (p = 0.0176) and HGS (p = 0.0018) showed improvement in T1.Conclusion ART combined with TDF / 3TC / DTG increased MIP and HGS after more than 50 days of treatment. Cohort studies are needed to better understand the action of these medications on PLWHA musculature under treatment.

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PERAN WARGA PEDULI AIDS CAHAYA CARE TUREN DALAM MENINGKATKAN KUALITAS HIDUP ODHA

Jurnal Kesehatan Mesencephalon ◽

10.36053/mesencephalon.v3i1.37 ◽

2017 ◽

Vol 3 (1) ◽

Author(s):

Tri Nurhudi Sasono

Keyword(s):

Quality Of Life ◽

Antiretroviral Drugs ◽

P Value ◽

People Living With Hiv ◽

Purposive Sampling ◽

Significant Difference ◽

Development Goals ◽

Living With Hiv ◽

Hiv Aids

Abstract : Indicator of the health welfare through Sustanable Development Goals (SDGs) is to reduce the incidence of HIV-AIDS, decrease the rate of the epidemic and maintain the quality of life of people living with HIV-AIDS (PLWHA). Trend cases of HIV-AIDS is the most recent spread among people, especially housewives. In Malang until 2015 found 278 Housewife of 409 cases of AIDS. The prevalence of HIV-AIDS in Malang Regency is ranked second after Surabaya city in East Java. For the importance of public participation and citizen care AIDS Cahaya Care Turen take responsibility for the condition. Determination Rule Goverment number 2 2015 year on the Participation of the community response to HIV-AIDS in Malang as a legal rule. Concerned Citizens activities AIDS (WPA). WPA Cahaya Care Turen is increases HIV risk and quality of life PLWHA. The purpose of this study was to determine the role of Citizens AIDS Cahaya Care Quality of Care Turen against people living with HIV in Puskesmas Turen Malang. The study design using a quasi-experimental, with purposive sampling using a sampling technique. Total number of research subjects 23. Based on test results obtained with the Wilcoxon p value <0.005, which means that there is a significant difference before and after PLWHA joining participated in the WPA Cahaya Care Turen. The conclusion of this study is WPA activities involving people living with HIV and at risk groups can optimize compliance with antiretroviral drugs that have an impact on improving the quality of life of PLHIV. Suggestions in this research is done WPA Program activities are structured and ongoing cross-sector in order to improve the quality of life and empower PLWHA.Keywords : WPA Cahaya Care Turen, Quality of life, PLWHA Abstrak : Salah satu indikator kesejahteraan kesehatan melalui Sustanable Development Goals (SDGs) adalah menekan angka kejadian HIV-AIDS, menurunkan laju epidemik dan mempertahankan kualitas hidup Orang dengan HIV-AIDS (ODHA). Trend kasus HIV-AIDS terkini terbanyak adalah menjangkit dikalangan masyarakat khususnya pada ibu rumah tangga. Kabupaten Malang sampai dengan tahun 2015 ditemukan 278 Ibu Rumah Tangga dari 409 kasus AIDS. Prevalensi HIV-AIDS di Kabupaten Malang ini merupakan peringkat kedua di Jawa Timur setelah Kota Surabaya. Untuk itu pentingnya peran serta masyarakat dan warga peduli AIDS Cahaya Care Turen ikut bertanggung jawab terhadap kondisi tersebut. Penetapan Peraturan Bupati Malang no.2 th.2015 tentang Peran serta masyarakat penanggulangan HIV-AIDS di Kabupaten Malang diharapkan dapat mengurangi risiko penularan HIV dan meningkatkan kualitas hidup ODHA. Tujuan dari penelitian ini adalah untuk mengetahui Peran Warga Peduli AIDS Cahaya Care Turen terhadap Kualitas ODHA Di Wilayah Kerja Puskesmas Turen Kabupaten Malang. Desain penelitian menggunakan quasi eksperimen, dengan teknik sampling menggunakan purposive sampling. Jumlah subyek penelitian sejumlah 23. Berdasarkan hasil uji dengan Wilcoxon didapatkan nilai p value < 0.005 yang berarti bahwa terdapat perbedaan bermakna sebelum dan sesudah ODHA bergabung mengikuti kegiatan WPA Cahaya Care Turen. Kesimpulan dalam penelitian ini adalah kegiatan WPA dengan melibatkan ODHA dan kelompok beresiko dapat mengoptimalkan kepatuhan obat ART sehingga berdampak terhadap peningkatan kualitas hidup ODHA. Saran dalam penelitian ini adalah dilakukannya Program kegiatan WPA yang terstruktur dan berkesinambungan lintas sektor guna meningkatkan kualitas hidup dan memberdayakan ODHA. Kata kunci : WPA Cahaya Care Turen, kualitas hidup, ODHA

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A pilot randomized controlled trial of a tailored smoking cessation program for people living with HIV in the Washington, D.C. metropolitan area

BMC Research Notes ◽

10.1186/s13104-020-05417-3 ◽

2021 ◽

Vol 14 (1) ◽

Author(s):

Elexis C. Kierstead ◽

Emily Harvey ◽

Denisse Sanchez ◽

Kimberly Horn ◽

Lorien C. Abroms ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Smoking Cessation ◽

Self Efficacy ◽

Text Messaging ◽

Controlled Trial ◽

P Value ◽

People Living With Hiv ◽

Randomized Controlled ◽

Living With Hiv ◽

Pilot Randomized Controlled Trial

Abstract Objective Morbidity and mortality from smoking-related diseases among people living with HIV (PLWH) in the U.S. surpasses that due to HIV itself. Conventional smoking cessation treatments have not demonstrated strong efficacy among PLWH. We conducted a pilot randomized controlled trial (RCT) to evaluate a tailored smoking cessation intervention based on the minority stress model. We compared standard of care counseling (SOC) to a tailored intervention (TI) including one face-to-face counseling session incorporating cognitive behavioral therapy to build resilience, and 30 days of 2-way text messaging. Results The primary outcome was smoking cessation. Secondary outcomes included cigarettes per day (CPD), exhaled carbon monoxide (CO), and cessation self-efficacy. A total of 25 participants were enrolled (TI:11, SOC:14), and 2 were lost to follow-up. There were no significant differences in quit rates between study groups. However, there was a significantly greater decrease in CPD in the TI versus SOC (13.5 vs. 0.0, p-value:0.036). Additionally, self-efficacy increased in both groups (TI p-value:0.012, SOC p-value:0.049) and CO decreased in both groups (TI p-value: < 0.001, SOC p-value:0.049). This intervention shows promise to support smoking cessation among PLWH. A larger study is needed to fully evaluate the efficacy of this approach. Clinical trial: Trial Registration: Retrospectively registered (10/20/2020) NCT04594109.

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STUDI RETROSPEKTIF KETAHANAN HIDUP ORANG DENGAN INFEKSI HIV/AIDS (ODHA) DI RSUD DR. ACHMAD MOCHTAR BUKITTINGGI

Human Care Journal ◽

10.32883/hcj.v3i3.89 ◽

2019 ◽

Vol 3 (3) ◽

pp. 175

Author(s):

Sukarsi Rusti

Keyword(s):

Opportunistic Infection ◽

Opportunistic Infections ◽

Analysis Data ◽

P Value ◽

People Living With Hiv ◽

Chi Square ◽

The People ◽

Living With Hiv ◽

Hiv Aids

HIV/AIDS disease is a health problem in indonesia. The problem cause of the number of morbility and mortality that still hight. It is cause of long term infection, adherance consuming the drungs and opportunistic that can deastroy the imun system of People Living With HIV/AIDS (PLHIV). The purpose of this research is to identify the factors related to the people living with PLHIV in Achmad Muchtar Hospital Bukittinggi2016.This research was conducted by a retrospective cohort design approach, doing research of the death of people who living with HIV by observing the patient’s medical record from 2014-2015. The research of study were 215 patient’s who is criteria inclusion. Analysis data using test chi-square. who became the independent variable is long infection, adherance comsuming the Anti Retroviral (ARV) , and opportunistic infection and dependent variable that survive the HIV people life.The research showed that among 215 patients with the number of deaths 39 people ( 18,% ), stages 3 and 4 (>5 th) is 89 people ( 41.4% ), not adherence is 77 people ( 35.8% ), and who suffered an opportunistic infection were 61 people (28.4% ). The statistical test relationships survival of people living with HIV with long-term infection obtained p value = 0,000 and RR = 0,019 ( confidence interfal 95 % with alpha = 0.05 ), adherance comsuming the ARV obtained p value = 0,000 and RR = 0,494 ( confidence interfal 95 % with alpha = 0.05 ), infection opportunistic obtained p value = 0,000 and RR = 0,361 ( confidence interfal 95 % with αlpha = 0.05 ).From these findings, it can be concluded that the long-term infection, adherence ARV and opportunistic infections associated with survival of people living with HIV. Of the three variables obtained interrelated and value the highest association is long-term infection.

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Respons Orang Hidup Dengan HIV AIDS (OHIDHA) Dalam Upaya Penanggulangan HIV AIDS di Kabupaten Sukoharjo dan Grobogan

JURNAL PROMOSI KESEHATAN INDONESIA ◽

10.14710/jpki.12.1.92-114 ◽

2017 ◽

Vol 12 (1) ◽

pp. 92

Author(s):

Arrum Firda Ayu Maqfiroch ◽

Zahroh Shaluhiyah

Keyword(s):

Univariate Analysis ◽

Hiv And Aids ◽

P Value ◽

People Living With Hiv ◽

Chi Square ◽

Cross Sectional ◽

The Status ◽

Keywords Aids ◽

Living With Hiv ◽

Hiv Aids

ABSTRAKPenanggulangan HIV AIDS membutuhkan keterlibatan dari berbagai pihak. Salah satu pihak yang terlibat adalah OHIDHA. OHIDHA merupakan anggota keluarga yang hidup bersama ODHA dan memberikan dukungan kepada ODHA. Stigma di Kabupaten Sukoharjo dan Grobogan masih tinggi. Penelitian ini bertujuan untuk mengetahui faktor-faktor apakah yang menentukan respons OHIDHA dalam upaya penanggulangan HIV AIDS di Kabupaten Sukoharjo dan Grobogan.Penelitian ini merupakan penelitian kuantitatif dengan pendekatan cross sectional. Teknik pengambilan data kuantitatif melalui wawancara dengan kuesioner. Penelitian ini didukung dengan penelitian kualitatif dengan teknik pengambilan data FGD. Jumlah responden adalah 92 OHIDHA, proporsi 50% dan selang kepercayaan 95%. Analisis data menggunakan analisis univariat dengan distribusi frekuensi, bivariat menggunakan Chi-Square dan multivariat menggunakan regresi logistik.Hasil penelitian menunjukkan bahwa variabel yang berhubungan dengan respons OHIDHA adalah hubungan dengan ODHA (p-value=0,001), lama hidup dengan ODHA (p-value=0,030), lama mengetahui status ODHA (p-value=0,001) dan sikap (p-value=0,005). Hasil analisis multivariat menunjukkan bahwa sikap (p-value=0,006) merupakan variabel yang mempunyai pengaruh paling signifikan dibanding variabel lainnya.Kata Kunci : OHIDHA, respons, Grobogan, Sukoharjo Respons of People Living With HIV AIDS to Control HIV and AIDS in Sukoharjo and Grobogan District; Controlling HIV and AIDS requird the involvement of various sector. One of the sector involved is People Living With HIV AIDS (PLWHA). PLWHA is a family member who lives with people living with HIV and provide support to people living with HIV. Stigma in Sukoharjo and Grobogan still high. This study aims to determine the factors that determine whether the PLWHA response in control to HIV and AIDS in Sukoharjo Grobogan. This research was a quantitative study with cross sectional approach. Quantitative data collection techniques through interviews with questionnaires . This research was supported by qualitative research with FGD. The number of respondents was 92 PLWHA, the proportion of 50% and 95% confidence interval . Analysis of the data using univariate analysis with frequency distribution, bivariate using Chi-Square and multivariate using logistic regression. The results showed that the variables related to the PLWHA response is a relationship with people living with HIV ( p = 0,001 ) , long life with people living with HIV ( p = 0.030 ) , longer know the status of PLWHA ( 0.001 ) and attitude ( p = 0.005 ). Multivariate analysis showed that the attitude (p value = 0,006) was a variable that has the most significant effect compared to other variables .Keywords : AIDS , response , Grobogan , Sukoharjo

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Knowledge and Behavior Change of People Living with HIV through Nutrition Education and Counseling

Kesmas National Public Health Journal ◽

10.21109/kesmas.v10i3.947 ◽

2016 ◽

Vol 10 (3) ◽

pp. 107

Author(s):

Fitri Hudayani ◽

Ratu Ayu Dewi Sartika

Keyword(s):

Treatment Group ◽

Behavior Change ◽

Nutrition Education ◽

Test Sample ◽

Control Group ◽

P Value ◽

People Living With Hiv ◽

Quasi Experimental ◽

And Behavior ◽

Living With Hiv

HIV, AIDS and nutrition are interconnected. In the HIV Integrated Care Unit of Dr. Cipto Mangunkusumo Public Hospital, nutrition education and counseling services are provided within a collaborative service for people living with HIV (PLWH). This study aimed to determine influence of nutrition education and counseling to knowledge and behavior of PLWH. This study was conducted with quasi experimental design using treatment and control groups. The treatment group consisted of 25 samples and 29 samples for control group. Samples were adults between 18 – 50 years old selected by applying inclusion and exclusion criteria. A pretested questionnaire was used to assess knowledge. Paired t-test sample was used to analyze data. This study was conducted on May – July 2014. Based on results of this study, there was effect in form of knowledge change (p value = 0.000) with score 6.38 point lower on the control group and any significant differences in behavior change (p value = 0.048) for the treatment group after receiving nutrition education and counseling. This study shows that nutrition and counseling using media of education which is more complete and continuously provided may improve knowledge and change behavior of PLWH.Perubahan Pengetahuan dan Perilaku Orang yang Hidup dengan HIVmelalui Konseling dan Edukasi GiziHIV, AIDS, dan gizi saling berhubungan. Pada Unit Pelayanan Terpadu HIV Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo, layanan edukasi dan konseling gizi disediakan secara kolaboratif untuk orang yang hidup dengan HIV. Penelitian ini bertujuan untuk mengetahui pengaruh pendidikan dan konseling gizi terhadap pengetahuan dan perilaku orang yang hidup dengan HIV. Penelitian ini dilakukan dengan desain kuasi eksperimental menggunakan kelompok perlakuan dan kontrol. Kelompok perlakuan terdiri dari 25 sampel dan 29 sampel untuk kelompok kontrol, dilakukan sebelum dan setelah perlakuan. Sampel berusia dewasa antara 18 – 50 tahun dipilih dengan menerapkan kriteria inklusi dan eksklusi. Sampel uji-t berpasangan digunakan untuk menganalisis data. Penelitian ini dilakukan pada bulan Mei – Juli 2014. Berdasarkan hasil penelitian, diketahui bahwa adanya efek berupa perubahan pengetahuan (nilai p = 0,000) dengan nilai 6,38 poin lebih rendah pada kelompok kontrol dan terdapat perbedaan yang signifikan dalam perubahan perilaku (nilai p = 0,048) untuk kelompok perlakuan setelah menerima edukasi dan konseling gizi. Penelitian ini menunjukkan bahwa edukasi dan konseling gizi menggunakan media edukasi yang lebih lengkap dan diberikan secara berkelanjutan dapat meningkatkan pengetahuan dan mengubah perilaku orang yang hidup dengan HIV.

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STADIUM HIV/AIDS DAN TINGKAT STRES: KORELASI KEDUANYA

JURNAL MUTIARA NERS ◽

10.51544/jmn.v4i1.1344 ◽

2021 ◽

Vol 4 (1) ◽

pp. 50-56

Author(s):

Ahmad Ikhlasul Amal ◽

Retno Setyawati

Keyword(s):

Sampling Technique ◽

P Value ◽

People Living With Hiv ◽

Test Results ◽

Physical Problems ◽

Level I ◽

Analytic Design ◽

Living With Hiv ◽

The Relationship ◽

Hiv Aids

Background: Infectious diseases that are still of concern to many circles, namely HIV / AIDS. This is confirmed by the reason that there is still an increase in the number of cases. In addition, this disease makes sufferers or people who are often known as people living with HIV / AIDS (PLWHA) experience both physical and psychological problems. The physical problems experienced by PLWHA, of course, depend on the stage of the patient's disease. PLWHA who experience physical problems may experience stress due to their illness. The purpose of this study was to determine the relationship between HIV stage and stress levels. Method: This type of research is a quantitative observational study with a correlation analytic design with consecutive sampling technique. Data collection was carried out by using a questionnaire with the number of respondents as many as 38 people. The data obtained were processed statistically using the Spearmen Rho statistical test. Results: based on the data, it was found that from 38 research respondents, most of them were 20-60 years old (76.3%). The majority of people with HIV / AIDS were male, namely 23 people (60.5%) with most of the occupations of HIV / AIDS sufferers being private (63.2%). Respondents' HIV was at stage II (50%) and III (50%). The level of stress experienced by HIV / AIDS sufferers is quite good, namely: at level I (31.57) and II (68.43). r = -174, p-value = 0.283. Conclusion: there is no correlation between HIV stage and stress level.

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Does undernutrition increase the risk of lost to follow-up in adults living with HIV in sub-Saharan Africa? Protocol for a systematic review and meta-analysis

BMJ Open ◽

10.1136/bmjopen-2020-048022 ◽

2021 ◽

Vol 11 (12) ◽

pp. e048022

Author(s):

Animut Alebel ◽

Daniel Demant ◽

Pammla Petrucka ◽

David Sibbritt

Keyword(s):

Systematic Review ◽

Effect Size ◽

Grey Literature ◽

Sub Saharan Africa ◽

People Living With Hiv ◽

Significance Level ◽

Sub Saharan ◽

Living With Hiv ◽

Lost To Follow Up

IntroductionUndernutrition is considered a marker for poor prognosis among people living with HIV (PLHIV), particularly in sub-Saharan Africa (SSA), where undernutrition and HIV are both highly prevalent. Evidence suggests that undernutrition (body mass index <18.5 kg/m2) is one of the main factors that significantly increases the risk of lost to follow-up (LTFU) in PLHIV. However, primary studies in SSA have reported inconsistent findings on the relationship between undernutrition and LTFU among adults living with HIV. To the best of our knowledge, no systematic review which aimed to summarise the available evidence. Hence, this review aims to determine the pooled effect of undernutrition on LTFU among adults living with HIV in SSA.Methods and analysisPubMed, EMBASE, Web of Science, Scopus, and, for grey literature, Google Scholar will be systematically searched to include relevant articles published since 2005. Studies reporting the effect of undernutrition on LTFU in adults living with HIV in SSA will be included. The Newcastle-Ottawa Scale will be used for quality assessment. Data from eligible studies will be extracted using a standardised data extraction tool. Heterogeneity between included studies will be assessed using Cochrane Q-test and I2 statistics. The Egger’s and Begg’s tests at a 5% significance level will be used to evaluate publication bias. As heterogeneity is anticipated, the pooled effect size will be estimated using a random-effects model. The final effect size will be reported using the adjusted HR with a 95% CI.Ethics and disseminationEthical approval is not required for a protocol for a systematic review. The results of this systematic review will be published in a peer-reviewed journal and will be publicly available.PROSPERO registration numberCRD42021277741.

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EFEKTIFITAS LACTACTION MASSAGE TERHADAP PENGELUARAN KOLOSTRUM PADA IBU NIFAS

Jurnal Kebidanan Malahayati ◽

10.33024/jkm.v7i2.3520 ◽

2021 ◽

Vol 7 (2) ◽

pp. 161-167

Author(s):

Ainun Mardhiah ◽

Riska Maulidanita ◽

Winda Agustina

Keyword(s):

Breast Milk ◽

Post Partum ◽

Wilcoxon Test ◽

Bivariate Analysis ◽

Control Group ◽

P Value ◽

Control Group Design ◽

Significance Level ◽

Purposive Sampling ◽

Group Design

THE EFFECTIVENESS OF LACTACTION MASSAGE ON COLOSTRUM EXPENDITURE IN THE PUBLIC MOTHER Background :Breastfeeding immediately after delivery provides many benefits for mothers and children. Breast milk that comes out for the first time contains colostrum which is highly nutritious and has antibodies that can protect newborns from disease. Based on the Demographic and Health Survey (IDHS), it is stated that more than half of children (57%) received breast milk within 1 hour after birth and 74 percent of children started breastfeeding within 1 day after birth.Purpose :Knowing to analyzing the effectiveness of lactaction massage on colostrum expenditure in postpartum mothersMethods:The research design used a pre-experimental design with a pretest-posttest control group design. Place of fresearch in the Medan City clinic in 2020.The population and sample in this study were all postpartum mothers on the first-third day totaling 24 people using purposive sampling technique. Comparison of 1: 1, where 12 respondents were intervened with lactaction massage and 12 respondents were the control group. The data that has been collected is processed by computer. Then analyzed the data, namely: Univariate and bivariate analysis using the Wilcoxon test with a significance level of 95% (0.05).Results: There is a difference in the average value of colostrum expenditure before and after the lactaction massage from 0.00 to 5.00. Wilcoxon test results obtained p value = 0.007 <0.05.Conclusion: There is the effectiveness of lactaction massage on colostrum expenditure in postpartum mothers.Suggestion: it is advisable to mothers who give birth to know complete information about the importance of giving colosrum to newborns. Keywords : Colostrum Expenditure, Lactaction Massage,Post Partum ABSTRAK Latar belakang: Pemberian ASI segera setelah melahirkan memberikan banyak manfaat bagi ibu dan anak. ASI yang keluar pertama kali mengandung kolostrum yang bergizi tinggi dan memiliki antibodi yang dapat melindungi bayi baru lahir dari penyakit. Berdasarkan Survei Demografi Dan Kesehatan (SDKI) menyatakan bahwa lebih dari separuh anak (57%) mendapatkan ASI dalam periode 1 jam setelah lahir dan 74 persen anak mulai disusui dalam 1 hari setelah lahir.Tujuan penelitian: untuk menganalisis efektifitas lactaction massage terhadap pengeluaran kolostrum pada ibu nifas.Metode: Desain penelitian menggunakan metode pre eksperimental design dengan pretest-posttest control group design. Tempat penelitian di klinik Kota Medan Tahun 2020. Populasi dan sampel seluruh ibu nifas hari pertama-ketiga berjumlah 24 orang dengan menggunakan teknik purposive sampling. Perbandingan 1:1, dimana 12 responden diintervensi lactaction massage dan 12 responden sebagai kelompok kontrol. Data yang telah dikumpulkan, diolah dengan komputer. Kemudian menganalisis data yaitu: Analisis univariat dan bivariat dengan menggunakan uji t test dengan tingkat kemaknaan 95% (0,05).Hasil: Terdapat perbedaan nilai rata-rata pengeluaran kolostrum sebelum dan setelah tindakan lactaction massage 0,00 menjadi 5,00. Hasil uji wilcoxon diperoleh nilai p = 0,007 < 0,05.Kesimpulan: Terdapat efektifitas lactaction massage terhadap pengeluaran kolostrum pada ibu nifas.Saran: Peneliti selanjutnya untuk meneliti variabel lainnya terkait lactaction massage dan pentingnya pemberian kolostrum pada bayi baru lahir. Kata Kunci: Pengeluaran Kolostrum, Lactaction Massage,Nifas

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Effect of Snakehead Fish Nugget and Colored Fruit Juice on Immune Response (CD4, TLC, and Leukocytes) in People Living with HIV (PLWHIV)

Indonesian Journal of Human Nutrition ◽

10.21776/ub.ijhn.2021.008.02.4 ◽

2021 ◽

Vol 8 (2) ◽

pp. 129

Author(s):

Ginta Siahaan ◽

Urbanus Sihotang ◽

Jujuren Sitepu ◽

Iceratnalela Siregar

Keyword(s):

Immune Response ◽

Fruit Juice ◽

Fruit Juices ◽

P Value ◽

People Living With Hiv ◽

Bioactive Substances ◽

Food Ingredients ◽

Post Test ◽

Living With Hiv ◽

The Impact

Human Immunodeficiency Virus (HIV) is a virus attacking the body's defense system in people living with HIV (PLHIV), such as Cluster Of Differentiation 4 (CD4), Leukocytes, and Total Lymphocyte Count (TLC). People infected with HIV require adequate macro and micronutrients to improve their quality of life. The content of protein, albumin, zinc, and bioactive substances contained in food ingredients can increase the immune response. Snakehead fish nuggets are rich in Albumin and Zn, while colored fruit juice contains bioactive substances and is high in Vitamin C. This study aimed to determine the impact of snakehead fish nuggets and colored fruit juices on CD4, leukocytes, and TLC in PLHIV in Medan. This research was a Quasi Experiment with a pre and post-test design. The sample represented an entire population of 36 people from all residents of the Rehabilitation Center and was then given the treatment of snakehead fish nuggets and colored fruit juices for 22 days. The data analysis was performed using the T-dependent test after the data were normally distributed. The results showed a treatment impact on CD4, leukocytes, and TLC in PLHIV with a p-value <0.05.

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