‘Moscow longevity’ program: effectiveness of physical activity in secondary prevention of hypertension

2020 ◽  
pp. 6-9
Author(s):  
N. V. Orlova ◽  
Ya. G. Spiryakina ◽  
I. M. Rud ◽  
A. N. Suanov ◽  
S. Yu. Gerasimova ◽  
...  

Regular aerobic exercise is recommended for the prevention and complex treatment of patients with hypertension. Increasing public awareness about modifiable risk factors and the introduction of various tools to help patients to improve these factors is one of the priority goals of modern healthcare. Regular physical activity lowers total blood cholesterol levels. ‘The Moscow longevity’ program helps patients of retirement age to increase their daily physical activity, to improve their mood, overall well-being and prognosis.

2018 ◽  
Vol 9 (2) ◽  
pp. 105-117
Author(s):  
Nanang Prayitno ◽  
Nila Dania Nardhiana ◽  
Ahmad Faridi ◽  
Meilinasari Meilinasari ◽  
Sugeng Wiyono

One of the changes with increasing age is the increase in total blood cholesterol levels. The purpose of this research is to know the relationship of  the consumption level of (energy, fat, and cholesterol), physical activity, and nutritional status with total blood cholesterol of the participants of Posbindu Anggrek Rosalina 45-59 years old  in Kelurahan Cibodas Baru Tangerang City 2015.This research use cross sectional design with population of all participants Posbindu Anggrek Rosalina age 45-59 years Kelurahan Cibodas Baru Tangerang City Year 2015. Sampling using purposive sampling technique and obtained 41 respondents. The results showed that average energy consumption was 1806.38 Calories / day, fat consumption level 71.84 gr / day, cholesterol consumption 238.87 mg / day, physical activity 1.49, nutritional status (BMI)  25.70 (overweight), and total blood cholesterol 212.66 mg / dl.Pearson correlation test showed that there was a significant correlation between energy consumption level (p = 0.045 <α = 0.05), fat consumption level (p = 0.039 <α = 0.05), and cholesterol consumption level (p = 0.016 <α = 0.05) with total blood cholesterol levels. There was no significant relationship between physical activity (p = 0.273> α = 0.05), whereas there was no correlation between nutritional status (p = 0.597> α = 0.05) with total blood cholesterol level.


2021 ◽  
Vol 6 (2) ◽  
pp. 40-43
Author(s):  
Syupiarni Putri Waruwu ◽  
Joseph Partogi Sibarani ◽  
Saharnauli Janna Verawaty Simorangkir

Background: Cholesterol is a fat that does not dissolve easily in the blood. Most of the cholesterol in the blood is attached to specific protein carriers in the plasma in the form of lipoprotein complexes, which are soluble in water. Lipoprotein which carries cholesterol throughout the body. namely LDL (Low Density Lipoprotein) and HDL (High Density Lipoprotein). An increase in LDL in the body tends to form atherosclerosis. In contrast HDL cholesterol inhibits LDL oxidation so that atherosclerotic plaque formation does not occur. Obesity is one of the risk factors for atherosclerosis with manifestations of coronary heart disease. Handling of obesity has been done by many researchers and implemented. One ingredient from nature that serves as an alternative ingredient to lower blood cholesterol levels is avocado. Objective: To determine the effect of avocado administration on total blood cholesterol levels in the obese college students at the Medical Faculty of Nommensen HKBP University in 2019. Methods :This research is a pre-experimental study with a pre-post test design in one group. The sample was selected by purposive sampling method and obtained 20 obese students. Subjects consumed avocado juice every day for 14 days. Total cholesterol levels were measured before (day 0) and after (day 14) treatment. Results: The mean total cholesterol level of the subject's blood on the pretest examination was 188.10 mg / dL and the posttest examination was 180.05 mg / dL. There was a decrease in the average total blood cholesterol level of 8.05 mg / dl. Paired T-test showed that there was a non-significant decrease in mean total blood cholesterol level with a value of p = 0.068 (p <0.05). Conclusion: In this study there was no effect of avocado administration on total blood cholesterol levels in obese students.


2018 ◽  
Vol 6 (2) ◽  
Author(s):  
Magdalena Talumewo ◽  
Murniati Tiho ◽  
Michaela E. Paruntu

Abstract: Unhealthy eating habit could lead to obesity. Obesity is always associated with the increase of blood cholesterol level (hypercholesterolemia). Increased cholesterol level is a risk factor of the death in young adult. This study was aimed to obtain the profile of total blood cholesterol levels among students of Faculty of Medicine Sam Ratulang University with body mass index (BMI) ≥23 kg/m2. This was a descriptive study. Samples were obtained by using total sampling method. There were 53 students involved in this study consisted of 22 males and 31 females. The results showed that 23 students (43.4%) had normal total cholesterol levels and 30 students (56.6 %) had low total cholesterol levels. Conclusion: More than half of the students of Faculty of Medicine Sam Ratulangi University with BMI ≥23 kg/m2 had low total cholesterol level.Keywords: total cholesterol, BMI ≥23 kg/m2. Abstrak: Kebiasaan makan yang tidak sesuai dengan kaidah sehat dapat mengakibatkan obesitas. Kondisi obesitas selalu dikaitkan dengan peningkatan kadar kolesterol dalam darah atau hiperkolesterolemia. Peningkatan kadar kolesterol merupakan factor risiko penyebab kematian di usia dewasa muda. Penelitian ini bertujuan untuk mengetahui gambaran kadar kolesterol total darah pada mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi dengan indeks massa tubuh (IMT) ≥23 kg/m2. Jenis penelitian ialah deskriptif. Sampel diperoleh dengan metode total sampling. Penelitian ini diikuti oleh 53 orang subyek penelitian yang terdiri dari 22 orang laki-laki dan 31 orang perempuan. Hasil penelitian mendapatkan 23 orang (43,4%) memiliki kadar kolesterol total normal dan 30 orang (56,6%) memiliki kadar kolesterol total rendah. Simpulan: Lebih dari setengah mahasiwa Fakultas Kedokteran Universitas Sam Ratulangi dengan IMT ≥23 kg/m2 memiliki kadar kolesterol total rendah.Kata kunci: kolesterol total, IMT ≥23 kg/m2


2008 ◽  
Vol 17 (1) ◽  
pp. 67-78 ◽  
Author(s):  
Yuko Kirihara ◽  
Kei Hamazaki ◽  
Tomohito Hamazaki ◽  
Yoichi Ogushi ◽  
Hisako Tsuji ◽  
...  

2006 ◽  
Vol 16 (4) ◽  
pp. 341-361 ◽  
Author(s):  
Lanae M. Joubert ◽  
Melinda M. Manore

Homocysteine is an independent cardiovascular disease (CVD) risk factor modi-fable by nutrition and possibly exercise. While individuals participating in regular physical activity can modify CVD risk factors, such as total blood cholesterol levels, the impact physical activity has on blood homocysteine concentrations is unclear. This review examines the influence of nutrition and exercise on blood homocysteine levels, the mechanisms of how physical activity may alter homocys-teine levels, the role of homocysteine in CVD, evidence to support homocysteine as an independent risk factor for CVD, mechanisms of how homocysteine increases CVD risk, and cut-off values for homocysteinemia. Research examining the impact of physical activity on blood homocysteine levels is equivocal, which is partially due to a lack of control for confounding variables that impact homocysteine. Duration, intensity, and mode of exercise appear to impact blood homocysteine levels differently, and may be dependent on individual fitness levels.


Author(s):  
Nurlaily Agustini ◽  
Arum Setiawan ◽  
Salni Salni

Pomegranate (Punica granatum L.) will be examined by looking at the ability between pomegranate extracts or fractions, which are more effective in lowering total blood cholesterol and triglyceride levels in mice. This study aims to determine the active pomegranate fraction that can reduce the total cholesterol levels and triglyceride in mice. The research method used was an experimental method with a Completely Randomized Design (CRD) which was divided into 6 treatment groups, and test animals divided into 6 treatment groups namely negative control given aquades, positive control fed a high-fat diet, given simvastatin, given 25 mg/grBB of pomegranate methanol fraction, given 50 mg/grBB of pomegranate methanol fraction, given 100 mg/grBB of pomegranate methanol fraction, each treatment group will be divided into 4 male mice.Based on the results of this study that the active fraction that has an effect in reducing blood cholesterol levels and mice triglycerides is the treatment given 100mg/grBB of pomegranate water methanol fraction.


2020 ◽  
Vol 331 ◽  
pp. 06005
Author(s):  
Usman Umar ◽  
Syafruddin Syarif ◽  
Ingrid Nurtanio ◽  
Indrabayu

Hypercholesterolemia causes cardiovascular disease which is a disorder of the heart and blood vessels, one of the most significant causes of death in the world, and this needs to be anticipated by monitoring blood cholesterol levels regularly. The current method of monitoring blood cholesterol levels is using invasive technique by collecting blood samples. A simple device is needed to measure blood cholesterol levels that can be done without collecting blood samples. This study aims to develop a non- invasive technique for monitoring blood cholesterol levels using sensors utilizing infrared light absorption in body tissues, in order to simplify measuring blood cholesterol levels regularly for patients with hypercholesterolemia. The application of a non-invasive technique focused on developing a total blood cholesterol monitoring device using an infrared sensor with IR LED - 940nm wavelength as a transmitter. A photodiode was used as a detector with the wavelength range of 400-1100 nm and a microcontroller as the minimum system for controlling the value of the output voltage in the form of digital data and then converted onto total blood cholesterol. The measurement results using non-invasive technique was compared to the results using invasive technique.


2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Lisa C. Ratulangi ◽  
Pemsi Wowor ◽  
Christi Mambo

Abstract: This study aimed to obtain the effect of pumpkin fruit pulp (Cucurbita moschata D.) juice on total blood cholesterol of wistar rats (Rattus norvegicus). This was an experimental laboratory study conducted in the Laboratory of Pharmacology and Therapy Faculty of Medicine, University of Sam Ratulangi. Samples were 10 rats with an average body weight of 150 g. Samples were divided into 5 groups, each group consisted of 2 rats: negative control group, only used standard food; propylthiouracil (PTU) treatment group; positive control group used simvastatin after PTU induced for 14 days; propylthiouracil (PTU) treatment group continued with standard food; and propylthiouracil (PTU) treatment group continued with pumpkin fruit pulp juice. Doses of the pumpkin fruit pulp juice were 0.93 g/ml/day/rat as many as 2 ml/day. The measurement of total blood cholesterol levels was on days 0, 15, and 22 by using Autocheck. Conclusion: The pumpkin fruit pulp juice had an effect in reducing total blood cholesterol levels in wistar rats.Keywords: juice of pumpkin fruit pulp, total blood cholesterol, propylthiouracil.  Abstrak: Penelitian ini bertujuan untuk mengetahui efek air perasan daging buah labu kuning (Cucurbita moschata D.) terhadap kadar kolesterol darah total pada tikus wistar (Rattus norvegicus). Jenis penelitian ini eksperimental laboratorik di Laboratorium Farmakologi dan Terapi Fakultas Kedokteran Universitas Sam Ratulangi. Subjek penelitian berupa tikus wistar jantan berjumlah 10 ekor dengan berat rata-rata 150 g yang dibagi kedalam 5 kelompok, masing-masing sebanyak 2 ekor, yaitu: kontrol negatif hanya menggunakan pakan standar; kelompok perlakuan propiltiourasil (PTU); kontrol positif menggunakan simvastatin setelah diinduksi PTU selama 14 hari; kelompok perlakuan pemberian PTU dilanjutkan dengan pakan standar; dan kelompok perlakuan pemberian PTU dilanjutkan dengan perasan daging buah labu kuning (Cucurbita moschata D.). Dosis perasan daging buah labu kuning yang diberikan 0.93 g/ml/hari/ekor sebanyak 2 ml/hari. Pengukuran kadar kolesterol darah total dilakukan pada hari ke 0, 15, dan 22 menggunakan alat pengukur Autocheck. Simpulan: Perasan daging buah labu kuning berefek menurunkan kadar kolesterol total pada tikus wistar.Kata kunci: perasan daging buah labu kuning, kolesterol total darah, propiltiourasil.


2016 ◽  
Vol 5 (3) ◽  
Author(s):  
Putri Mira Magistri ◽  
Rismawati YaswiR ◽  
Yustini Alioes

AbstrakMasyarakat menggunakan berbagai cara pengolahan sebelum mengonsumsi telur yang dapat berpengaruh terhadap kadar zat gizi yang terkandung didalamnya, termasuk kadar kolesterol dalam telur yang juga akan mempengaruhi kadar kolesterol dalam darah. Tujuan penelitian ini adalah menentukan pengaruh pemberian berbagai olahan telur terhadap kadar kolesterol total darah mencit. Penelitian menggunakan 24 ekor mencit (Mus musculus) jantan albino umur 3 – 4 bulan dengan berat badan sekitar 30 – 40 gram. Jenis kandang yang digunakan adalah kandang kotak (box) sebanyak 24 unit dengan ukuran 28x30x20 cm. Metode yang digunakan ialah eksperimen dengan Rancangan Acak Lengkap (RAL) terdiri dari 6 unit perlakuan, yaitu unit perlakuan K (Kontrol), unit perlakuan A (telur mentah), unit perlakuan B (telur goreng), unit perlakuan C (telur rebus), unit perlakuan D (telur setengah matang) dan unit perlakuan E (telur asin). Dosis perlakuan adalah 1,56ml/20gram berat badan/mencit dan masing-masing perlakuan diulang 4 kali. Parameter yang diukur adalah kadar kolesterol total darah mencit. Hasil analisis keragaman menunjukan bahwa pemberian berbagai olahan telur memberikan pengaruh berbeda sangat nyata (P<0.01) terhadap kadar kolesterol total darah mencit. Berdasarkan hasil penelitian dapat disimpulkan bahwa rerata kadar kolesterol total darah mencit setelah diberikan berbagai olahan telur adalah telur mentah 106.96 mg/dl, telur goreng 143.53 mg/dl, telur rebus 194.50 mg/dl, telur setengah matang 180.91 mg/dl, dan telur asin 158.27 mg/dl.Kata kunci: olahan telur, kadar kolesterol total darah, mencit AbstractPeople use various methods of processing before consumption eggs which can affect the levels of nutrients contained in, including cholesterol content which can also affect the levels of total cholesterol in blood. The objective of this study was to determine the effect of giving a variety of processed egg on total cholesterol levels of mice. The experiment used 24 male albino mice (Mus nusculus) age 3 – 4 months old with 30 – 40 grams of body weight. The den used was 24 units of box with size of 28x30x20 cm. The experiment used Completely Randomized Design (CRD) consist of 6 treatment units which was K (control), A (raw egg), B (fried egg), C (boiled egg), D (soft-boiled egg), and E (salted egg). The dosage was  1.56 ml/20 grams of body weight/mice and 4 replication for each treatment units. The parameter measured was total blood cholesterol level of mice.  Results of analysis of variance showed that giving of a variety of processed egg gave highly  significant  effect (P <0.01) on total blood cholesterol levels of mice. Based on the results of this study, it can be concluded that the average total blood cholesterol levels of mice after giving of various preparations of eggs is as follows: raw eggs 106.96 mg / dl, fried eggs 143.53 mg / dl, boiled eggs 194.50 mg / dl, soft-boiled eggs 180.91 mg / dl, and salted egg 158.27 mg / dl..Keywords: processed egg, total blood cholesterol level,  mice


Author(s):  
Istianatus Sunnah ◽  
Erna Kustiyaningsih ◽  
Dian Oktianti

Hyperlipidemia is a risk factor for various diseases, which is still a big problem in Indonesia. Yellow pumpkin (Cucurbita maxima D.) is a plant containing flavonoids and terpenoids, which can be used as an anti-hypercholesterolemic agent. This study aims to analyze the activity and dosage of yellow pumpkin extract, which can be used as an anti-hypercholesterolemic agent to reduce total cholesterol levels comparable to simvastatin by 1.8mg/kg BW/day. This research is pure experimental research with a pre and post-test group design approach. The number of samples was 25 male Wistar rats induced by high-fat feed, quail egg yolk: pork oil (2:1) by 5 ml/200 gramBW/day for 7 days. The extract dosage range was 200, 400, 600 mg/kg BW/ day  for 7 days. Data were analyzed using One Way ANOVA. The results showed that the administration of yellow pumpkin extract could reduce rats' total blood cholesterol levels with a dose of 600 mg/kg BW/day, comparable to simvastatin 1.8 mg/kg BW/day. The secondary metabolites of the extract were flavonoids and terpenoids. Extract of yellow pumpkin (Cucurbita maxima D.) could reduce total blood cholesterol levels of rats. The dose of 600 mg/kg BW/day could reduce blood cholesterol levels in rats comparable to simvastatin 1.8 mg/kg BW / day.


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