Comparing the Different Manifestations of Postpartum Mental Disorders by Origin, among Immigrants and Native-Born in Israel According to Different Mental Scales

We conducted a prospective study, aimed to study whether the prevalence of mental disorders after birth differs by country of origin. Parturient mothers of Ethiopian origin, Former-USSR (FSU) origin, or nonimmigrant, native-Israeli origin (n = 974, all Jewish) were recruited in hospitals in Israel and were followed 6–8 weeks and one year after birth. General linear models were used to study the associations between origin and mental health, comparing Ethiopian and FSU origin with native-Israeli. Ethiopian and FSU mothers were more likely to report on somatic symptoms, compared with native-Israeli women. Ethiopian origin was negatively and significantly associated with anxiety in all three interviews (β = −1.281, β = −0.678 and β = −1.072, respectively; p < 0.05 in all). FSU origin was negatively associated with depression after birth (β = −0.709, p = 0.036), and negatively associated with anxiety after birth and one-year postpartum (β = −0.494, and β = −0.630, respectively). Stressful life events were significantly associated with all mental disorders in the three time points of interviews. Our findings suggest that immigrants tend to express higher mental distress with somatic symptoms. Additional tools are needed for mental distress screening among immigrants.

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Socio-economic consequences of mental distress: quantifying the impact of self-reported mental distress on the days of incapacity to work and medical costs in a two-year period: a longitudinal study in Germany

BMC Public Health ◽

10.1186/s12889-021-10637-8 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Gerhard Müller ◽

Manuela Bombana ◽

Monika Heinzel-Gutenbrenner ◽

Nikolaus Kleindienst ◽

Martin Bohus ◽

...

Keyword(s):

Mental Disorders ◽

Mental Distress ◽

Linear Models ◽

Longitudinal Research ◽

Depression Scale ◽

Routine Data ◽

Medical Costs ◽

First Year ◽

Second Year ◽

The Impact

Abstract Background Mental disorders are related to high individual suffering and significant socio-economic burdens. However, it remains unclear to what extent self-reported mental distress is related to individuals’ days of incapacity to work and their medical costs. This study aims to investigate the impact of self-reported mental distress for specific and non-specific days of incapacity to work and specific and non-specific medical costs over a two-year span. Method Within a longitudinal research design, 2287 study participants’ mental distress was assessed using the Hospital Anxiety and Depression Scale (HADS). HADS scores were included as predictors in generalized linear models with a Tweedie distribution with log link function to predict participants’ days of incapacity to work and medical costs retrieved from their health insurance routine data during the following two-year period. Results Current mental distress was found to be significantly related to the number of specific days absent from work and medical costs. Compared to participants classified as no cases by the HADS (2.6 days), severe case participants showed 27.3-times as many specific days of incapacity to work in the first year (72 days) and 10.3-times as many days in the second year (44 days), and resulted in 11.4-times more medical costs in the first year (2272 EUR) and 6.2-times more in the second year (1319 EUR). The relationship of mental distress to non-specific days of incapacity to work and non-specific medical costs was also significant, but mainly driven from specific absent days and specific medical costs. Our results also indicate that the prevalence of presenteeism is considerably high: 42% of individuals continued to go to work despite severe mental distress. Conclusions Our results show that self-reported mental distress, assessed by the HADS, is highly related to the days of incapacity to work and medical costs in the two-year period. Reducing mental distress by improving preventive structures for at-risk populations and increasing access to evidence-based treatments for individuals with mental disorders might, therefore, pay for itself and could help to reduce public costs.

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Anxiety, depression and stressful life events among medical students: a prospective study in Antalya, Turkey

Medical Education ◽

10.1046/j.1365-2923.2001.00726.x ◽

2001 ◽

Vol 35 (1) ◽

pp. 12-17 ◽

Cited By ~ 146

Author(s):

Mehmet Aktekin ◽

Taha Karaman ◽

Yesim Yigiter Senol ◽

Sukru Erdem ◽

Hakan Erengin ◽

...

Keyword(s):

Medical Students ◽

Prospective Study ◽

Life Events ◽

Stressful Life Events ◽

Stressful Life ◽

A Prospective Study ◽

Anxiety Depression

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Evaluation of Breast Lumps by Ultrasound and Correlation with Histological Findings

Journal of Surgical Sciences ◽

10.3329/jss.v23i1.44238 ◽

2020 ◽

Vol 23 (1) ◽

pp. 10-12

Author(s):

Nelema Jahan ◽

Md. Mamunur Rahman ◽

Mohammad Shahidul Alam ◽

Md Saiful Islam

Keyword(s):

Histopathological Examination ◽

Breast Diseases ◽

Histopathological Study ◽

Common Symptom ◽

Breast Lump ◽

Histopathological Findings ◽

Malignant Breast ◽

Breast Lumps ◽

One Year ◽

A Prospective Study

Background: A breast lump is the most common symptom associated with both benign and malignant breast diseases. Therefore, a distinction of benign from malignant lump is of importance for proper management. Though a definitive diagnosis is possible with imaging for all the lesions, histopathological study is proven essential for confirming the diagnosis. Objective: The objective of this study was to evaluate the role of USG and histopathological findings of different breast lump in diagnosis and their comparison. Methods: A prospective study was conducted over a period of one year from January 2017 to December 2017. A total of 116 patients were included in this study. All breast lumps underwent surgery and the ultrasound findings of these lumps were compared with the histopathological findings. Data were collected from these patients by a preformed questionnaire and finally the data were analyzed. Results: Out of 116 patients only 21 cases were reported as malignant in ultrasound report but histopathology revealed 31 malignant patients. On histopathological examination 10 benign cases turned out to be malignant. Conclusion: The present study was undertaken to evaluate in diagnosing breast mass lesions individually by ultrasound and compared with histopathology for definitive management of a patient. Journal of Surgical Sciences (2019) Vol. 23 (1) : 10-12

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Wider-community Segregation and the Effect of Neighbourhood Ethnic Diversity on Social Capital: An Investigation into Intra-Neighbourhood Trust in Great Britain and London

Sociology ◽

10.1177/0038038516641867 ◽

2016 ◽

Vol 51 (5) ◽

pp. 1011-1033 ◽

Cited By ~ 15

Author(s):

James Laurence

Keyword(s):

Social Capital ◽

Great Britain ◽

Ethnic Diversity ◽

Linear Models ◽

Critical Role ◽

Hierarchical Linear Models ◽

Negatively Associated ◽

Community Segregation ◽

Do So

Extensive research has demonstrated that neighbourhood ethnic diversity is negatively associated with intra-neighbourhood social capital. This study explores the role of segregation and integration in this relationship. To do so it applies three-level hierarchical linear models to two sets of data from across Great Britain and within London, and examines how segregation across the wider-community in which a neighbourhood is nested impacts trust amongst neighbours. This study replicates the increasingly ubiquitous finding that neighbourhood diversity is negatively associated with neighbour-trust. However, we demonstrate that this relationship is highly dependent on the level of segregation across the wider-community in which a neighbourhood is nested. Increasing neighbourhood diversity only negatively impacts neighbour-trust when nested in more segregated wider-communities. Individuals living in diverse neighbourhoods nested within integrated wider-communities experience no trust-penalty. These findings show that segregation plays a critical role in the neighbourhood diversity/trust relationship, and that its absence from the literature biases our understanding of how ethnic diversity affects social cohesion.

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Persistent level of mental distress in PTSD patients is not reflected in cytokine levels one year after treatment

Acta Neuropsychiatrica ◽

10.1017/neu.2021.11 ◽

2021 ◽

pp. 1-22

Author(s):

Helge Toft ◽

Jørgen Bramness ◽

Terje Tilden ◽

Ingeborg Bolstad ◽

Lars Lien

Keyword(s):

Inflammatory Markers ◽

Mental Distress ◽

Psychiatric Treatment ◽

Blood Collection ◽

Post Traumatic Stress ◽

Global Severity Index ◽

Cytokine Levels ◽

One Year ◽

Circulating Inflammatory Markers

Abstract Objective Cross-sectional data show that Post-Traumatic Stress Disorder (PTSD) patients often have increased levels of circulating inflammatory markers. There is, however, still a paucity of longitudinal studies with long follow-up times on levels of cytokines in such patients. The current study assesses patients with and without PTSD diagnosis one year after discharge from inpatient treatment. Methods Patients in treatment for serious non-psychotic mental disorders were recruited at the beginning of their treatment stay at a psychiatric center in Norway. Ninety patients submitted serum samples and filled out the Hopkins Symptom Checklist-90 Revised Global Severity Index (HSCL-90R GSI) questionnaire during their main stay and at a follow-up stay one year after discharge. Of these patients, 33 were diagnosed with PTSD, 48 with anxiety, depression or eating disorder, while nine patients had missing data. The patients were diagnosed using the Mini-International Neuropsychiatric Interview (M.I.N.I.). Results At the follow-up stay (T3), PTSD patients had higher levels of GSI scores than non-PTSD patients (p = 0.048). These levels were unchanged from the year before (T2) in both groups. The levels of circulating cytokines/chemokine did not differ between the PTSD and non-PTSD patients at T3. At T2, however, the PTSD and non-PTSD groups exhibited different levels of IL-1β (p = 0.053), IL-1RA (p = 0.042) and TNF-α (p = 0.037), with the PTSD patients having the higher levels. Conclusion Despite exhibiting different mental distress scores, the PTSD and non-PTSD patients did not differ regarding levels of circulating inflammatory markers at one-year follow-up. Significant outcome PTSD and non-PTSD patients show persistently different scores of mental distress one year after psychiatric treatment. In contrast, their cytokine levels do not differ one year after discharge from a psychiatric treatment inpatient stay. Limitations The patients with higher scores of mental distress were those who attended the follow-up stay, introducing a selection bias to the study. Further, it was not assessed whether the patients were fasting or smoking cigarettes prior to blood collection, or their sleeping or physical exercise status.

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Zika RNA and Flavivirus-Like Antigens in the Sperm Cells of Symptomatic and Asymptomatic Subjects

Viruses ◽

10.3390/v13020152 ◽

2021 ◽

Vol 13 (2) ◽

pp. 152

Author(s):

Hernan Vanegas ◽

Fredman González ◽

Yaoska Reyes ◽

Edwing Centeno ◽

Jayrintzina Palacios ◽

...

Keyword(s):

Clinical Symptoms ◽

Time Frame ◽

Sperm Cells ◽

Human Semen ◽

Zikv Infection ◽

Virus Shedding ◽

One Year ◽

Asymptomatic Subjects ◽

A Prospective Study ◽

Male Subjects

Zika virus (ZIKV) RNA has been found to remain in human semen for up to one year after infection, but the presence of Flavivirus antigens in the different compartments of semen has been largely unexplored. Following the introduction of ZIKV in Nicaragua (2016), a prospective study of patients with clinical symptoms consistent with ZIKV was conducted in León to investigate virus shedding in different fluids. ZIKV infection was confirmed in 16 male subjects (≥18 years of age) by RT-qPCR in either blood, saliva or urine. Of these, three provided semen samples at 7, 14, 21, 28, 60 and 180 days postsymptom onset (DPSO) for Flavivirus antigens and RNA studies. These cases were compared with 19 asymptomatic controls. Flavivirus antigens were examined by immunofluorescence (IF) using the 4G2 Mabs, and confocal microscopy was used to explore fluorescence patterns. The three (100%) symptomatic subjects and 3 (16%) of the 19 asymptomatic subjects had Flavivirus antigens and viral RNA in the spermatozoa fraction. The percentage of IF Flavivirus-positive spermatozoa cells ranged from 1.9% to 25% in specimens from symptomatic subjects, as compared with 0.8% to 3.8% in specimens from asymptomatic controls. A marked IF-pattern in the cytoplasmic droplets and tail of the spermatozoa was observed. The sperm concentrations (45 × 106/mL vs. 63.5 × 106/mL, p = 0.041) and the total motility percentage (54% vs. 75%, p = 0.009) were significantly lower in specimens from ZIKV-positive than in those of ZIKV-negative. In conclusion, this study demonstrated the presence of Flavivirus antigens and RNA within a time frame of 28 DPSO in sperm cells of symptomatic and asymptomatic subjects during the ZIKV epidemic. These findings have implications for public health, in terms of nonarthropod-born, silent transmission facilitated by sperm cells and potential transmission from asymptomatic males to pregnant women, with consequences to the fetus.

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Diet, Exercise, Lifestyle, and Mental Distress among Young and Mature Men and Women: A Repeated Cross-Sectional Study

Nutrients ◽

10.3390/nu13010024 ◽

2020 ◽

Vol 13 (1) ◽

pp. 24

Author(s):

Lina Begdache ◽

Saloumeh Sadeghzadeh ◽

Gia Derose ◽

Cassandra Abrams

Keyword(s):

Young Women ◽

Fast Food ◽

Mental Distress ◽

Young Men ◽

Brain Morphology ◽

Mental Wellbeing ◽

Caffeine Consumption ◽

Cross Sectional ◽

Men And Women ◽

Negatively Associated

Customization of mental health therapies needs to consider the differences in degree of brain maturity between young (18–29 years) and mature (30 years or older) adults as well as brain morphology among men and women. The aim of this study was to identify the significant dietary and lifestyle contributors to mental distress in these sub-populations. Independent repeated cross-sectional sampling was performed for over a 5-year period (2014–2019) to collect data from different populations at different time-points and seasons. A backward stepwise regression analysis was used on 2628 records. Mental distress in young women was associated with high consumption of caffeine and fast-food, and it was negatively correlated with moderate-high levels of exercise as well as frequent breakfast consumption. Mature women shared several common factors with young women; however, high fruit consumption was negatively associated with mental distress. For young men, high exercise, moderate consumption of dairy, and moderate-high intake of meat were negatively associated with mental distress. In addition, high fast-food and caffeine consumption were positively associated with mental distress in young men. For mature men, strong negative associations between higher education, moderate intake of nuts and mental distress surfaced. Our results support the need to customize dietary and lifestyle recommendations to improve mental wellbeing.

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Customised gold weight eyelid implantation in paralytic lagophthalmos

The Journal of Laryngology & Otology ◽

10.1017/s0022215108001886 ◽

2008 ◽

Vol 122 (10) ◽

pp. 1088-1091 ◽

Cited By ~ 7

Author(s):

N Jayashankar ◽

K P Morwani ◽

M J Shaan ◽

S R Bhatia ◽

K T Patil

Keyword(s):

Visual Acuity ◽

Prospective Study ◽

Study Design ◽

Study Group ◽

Upper Eyelid ◽

Eyelid Closure ◽

Gold Weight ◽

One Year ◽

A Prospective Study

AbstractGold eyelid implantation is widely considered the procedure of choice to reanimate the upper eyelid in paralytic lagophthalmos. Commercially supplied implants are not readily available in all places and are sometimes cumbersome to import.Objective:We aimed to devise a method whereby every surgeon performing gold eyelid implantation could have easy and quick access to the implant. Furthermore, we aimed to develop a means of creating an implant of the exact weight required for complete eyelid closure.Study design and setting:A prospective study was performed from 1997 to 2005 in a tertiary research hospital, involving 50 subjects requiring gold upper eyelid implantation and using the technique in question.Results:Only patients with a minimum follow up of one year were included in the study group. Symptoms improved in 96 per cent of subjects, who were able to dispense with eyedrops and eye ointments. Visual acuity improved in 92 per cent of patients. There were two extrusions amongst the early cases.Conclusion and significance:Customised gold eyelid implantation offers an alternative in regions where commercial implants are not easily obtained.

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Performance of the Surprise Question Compared to Prediction Models in Hemodialysis Patients: A Prospective Study

American Journal of Nephrology ◽

10.1159/000481920 ◽

2017 ◽

Vol 46 (5) ◽

pp. 390-396 ◽

Cited By ~ 4

Author(s):

Rakesh Malhotra ◽

Xia Tao ◽

Yuedong Wang ◽

Yuqi Chen ◽

Rebecca H. Apruzzese ◽

...

Keyword(s):

Linear Models ◽

Prediction Models ◽

Clinical Laboratory ◽

Mortality Prediction ◽

Operating Characteristics ◽

Dialysis Treatment ◽

Mortality Probability ◽

A Prospective Study ◽

Surprise Question

Background: The surprise question (SQ) (“Would you be surprised if this patient were still alive in 6 or 12 months?”) is used as a mortality prognostication tool in hemodialysis (HD) patients. We compared the performance of the SQ with that of prediction models (PMs) for 6- and 12-month mortality prediction. Methods: Demographic, clinical, laboratory, and dialysis treatment indicators were used to model 6- and 12-month mortality probability in a HD patients training cohort (n = 6,633) using generalized linear models (GLMs). A total of 10 nephrologists from 5 HD clinics responded to the SQ in 215 patients followed prospectively for 12 months. The performance of PM was evaluated in the validation (n = 6,634) and SQ cohorts (n = 215) using the areas under receiver operating characteristics curves. We compared sensitivities and specificities of PM and SQ. Results: The PM and SQ cohorts comprised 13,267 (mean age 61 years, 55% men, 54% whites) and 215 (mean age 62 years, 59% men, 50% whites) patients, respectively. During the 12-month follow-up, 1,313 patients died in the prediction model cohort and 22 in the SQ cohort. For 6-month mortality prediction, the GLM had areas under the curve of 0.77 in the validation cohort and 0.77 in the SQ cohort. As for 12-month mortality, areas under the curve were 0.77 and 0.80 in the validation and SQ cohorts, respectively. The 6- and 12-month PMs had sensitivities of 0.62 (95% CI 0.35–0.88) and 0.75 (95% CI 0.56–0.94), respectively. The 6- and 12-month SQ sensitivities were 0.23 (95% CI 0.002–0.46) and 0.35 (95% CI 0.14–0.56), respectively. Conclusion: PMs exhibit superior sensitivity compared to the SQ for mortality prognostication in HD patients.

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