scholarly journals Benzo[1,2,3]dithiazole Compounds: A History of Synthesis and Their Renewed Applicability in Materials and Synthetic Chemistry, Originating from the Herz Reaction

Reactions ◽  
2021 ◽  
Vol 2 (3) ◽  
pp. 175-208
Author(s):  
Alexander J. Nicholls ◽  
Ian R. Baxendale
Keyword(s):  
Organic Dyes ◽  
Diagnostic Techniques ◽  
Organic Radicals ◽  
Small Scale ◽  
Materials Chemistry ◽  
Commercial Scale ◽  
Potential Applicability ◽  
History Of ◽  
Design And Manufacture ◽  
Synthetic Intermediate

The benzo[1,2,3]dithiazole is a unique heteroaromatic functionality whose conjugated profile instils some fascinating electronic properties. This has been historically recognized in the design and manufacture of organic dyes early last century. Although, with the benefit of increased diagnostic techniques and improved understanding, these structures are attracting greater attention in additional research settings, including applications as organic radicals and semiconductors. In addition, the benzodithiazole functionality has been shown to be a valuable synthetic intermediate in the preparation of a variety of other privileged aromatic and heteroaromatic targets, many of which are important APIs. In this review, the authors aim to critically analyse the potential applicability of these compounds to the fields of not only small-scale laboratory synthetic and medicinal chemistry but also commercial-scale processes and increasingly materials chemistry.

Craft Beer's Unlikely Alchemist

2019 ◽  
Vol 19 (4) ◽  
pp. 78-90
Author(s):  
Theresa McCulla
Keyword(s):  
San Francisco ◽  
Assembly Line ◽  
The United States ◽  
Risk Tolerance ◽  
Small Scale ◽  
Intellectual Curiosity ◽  
Brewing Industry ◽  
Washing Machine ◽  
Craft Beer ◽  
History Of

In 1965, Frederick (Fritz) Maytag III began a decades-long revitalization of Anchor Brewing Company in San Francisco, California. This was an unexpected venture from an unlikely brewer; for generations, Maytag's family had run the Maytag Washing Machine Company in Iowa and he had no training in brewing. Yet Maytag's career at Anchor initiated a phenomenal wave of growth in the American brewing industry that came to be known as the microbrewing—now “craft beer”—revolution. To understand Maytag's path, this article draws on original oral histories and artifacts that Maytag donated to the Smithsonian Institution's National Museum of American History via the American Brewing History Initiative, a project to document the history of brewing in the United States. The objects and reflections that Maytag shared with the museum revealed a surprising link between the birth of microbrewing and the strategies and culture of mass manufacturing. Even if the hallmarks of microbrewing—a small-scale, artisan approach to making beer—began as a backlash against the mass-produced system of large breweries, they relied on Maytag's early, intimate connections to the assembly-line world of the Maytag Company and the alchemy of intellectual curiosity, socioeconomic privilege, and risk tolerance with which his history equipped him.

Study of Diabetic Mellitus and Knowledge of Lotion Foot Care on the Community

2018 ◽  
Vol 9 (3) ◽  
Author(s):  
Hariyadi DM ◽  
Athiyah U ◽  
Hendradi E ◽  
Rosita N ◽  
Erawati T ◽  
...  
Keyword(s):  
Blood Glucose ◽  
T Test ◽  
Small Scale ◽  
Scale Production ◽  
Foot Care ◽  
Diabetic Mellitus ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Before And After ◽  
History Of

The prevention of Diabetic Mellitus (DM) and its complications is the main aim of this study, in addition to the training of lotion foot care application and the development of small scale industry. The research team delivered knowledge in the form of training on Diabetic Mellitus, healthy food, treatment and prevention of complications, and small-scale production of cosmetic products. The aim of this study was to determine the correlation between training on diabetic and lotion foot care application as preventive measures against diabetic complications on the patient's blood glucose levels in the community of residents in Banyuurip Jaya, Surabaya. It was expected from this training that the knowledge of the residents increases and people living with diabetic undergo lifestyle changes and therefore blood sugar levels can be controlled. The parameters measured in this research were blood glucose levels, the anti diabetic drug types consumed, and compliance on diabetics. This study used the data taken from 60 patients with DM over a period of one month. Questionnaires and log books was used to retrieve data and changes in blood glucose levels in diabetic patients. The results showed the demographic data of patients with type 2 diabetic of 85% female and 15% male, with the range of patients aged of 61-70 years of 46.67% and had history of diabetic (90%). The history of drugs consumed by respondents was anti diabetic drugs such as metformin (40%), glimepiride (33.37%) and insulin (6.67%). In addition, the increased knowledge of DM patients after being given the training compared to before training was shown in several questions in the questionnaire. A statistical analysis using t-test analyzed a correlation between training provided in order to enhance understanding of the patient, as well as correlation with blood glucose levels. A paired T-test showed that there was a relationship between the knowledge of trainees before and after training (p less than 0.05). An interesting result was that there was no relationship between blood glucose levels before and after training provided (p> 0.05).

Design and Operation of Small Wastewater Treatment Plants by the Microbial Film Process

1990 ◽  
Vol 22 (3-4) ◽  
pp. 139-144 ◽  
Author(s):  
S. Iwai ◽  
Y. Oshino ◽  
T. Tsukada
Keyword(s):  
Urban Areas ◽  
Wastewater Treatment Plants ◽  
Waste Water Treatment ◽  
Small Scale ◽  
Small Communities ◽  
Fishing Villages ◽  
Sewer Systems ◽  
Water Treatment Plants ◽  
History Of ◽  
Microbial Film

Although the ratio of sewer systems to population in Japan has been improving in recent years, the construction of sewer systems in small communities such as farming or fishing villages, etc. had lagged behind that of urban areas. However, construction of small-scale sewer systems in farming and fishing villages has been actively carried out in recent years. This report explains the history of the promotion of small-scale sewer systems, why submerged filter beds are being employed in many cases, and introduces the design, operation and maintenance of representative waste-water treatment plants in farming and fishing villages which incorporate de-nitrogen and dephosphorization.

Dysbaric osteonecrosis associated with decompression sickness in a fishing diver

2019 ◽  
pp. 217-220
Author(s):  
Eduardo Briceño-Souza ◽  
◽  
Nina Méndez-Domínguez ◽  
Ricardo j Cárdenas-Dajda ◽  
Walter Chin ◽  
...  
Keyword(s):  
Femoral Head ◽  
Decompression Sickness ◽  
Small Scale ◽  
Prior History ◽  
Radiological Findings ◽  
Small Scale Fisheries ◽  
Left Limb ◽  
History Of ◽  
Decompression Stress ◽  
Probable Diagnosis

Diving as a method of fishing is used worldwide in small-scale fisheries. However, one of the main causes of morbidity and mortality among fishermen is decompression sickness (DCS). We report the case of a 46-year-old male fisherman diver who presented with chronic inguinal pain that radiated to the lower left limb. Living and working in a fishing port in Yucatan, he had a prior history of DCS. A diagnosis of avascular necrosis in the left femoral head secondary to DCS was made via analysis of clinical and radiological findings. The necrosis was surgically resolved by a total hip arthroplasty. Dysbaric osteonecrosis is a more probable diagnosis. In this region fishermen undergo significant decompression stress in their daily fishing efforts. Further studies regarding prevalence of dysbaric osteonecrosis among small-scale fisheries divers are needed. In a community where DCS is endemic and has become an epidemic, as of late, the perception of this health risk remains low. Furthermore, training and decompression technique are lacking among the fishing communities.

Knowledge, attitudes and practice of family planning: profile of a Bedouin community in Saudi Arabia

1974 ◽  
Vol 6 (4) ◽  
pp. 453-461 ◽  
Author(s):  
Zohair A. Sebai
Keyword(s):  
Saudi Arabia ◽  
Family Planning ◽  
Social Status ◽  
Small Scale ◽  
Age Group ◽  
The Social ◽  
The Family ◽  
History Of ◽  
Or History

SummaryFamily planning is not being practised in Wadi Turaba in western Saudi Arabia, which is a Bedouin community with different stages of settlement. Children are wanted in the family, and the more children, especially boys, the better the social status of the family in the community. The desire of a mother for more children does not appear to be affected by her age group, history of previous marriages or history of previous pregnancies.Knowledge about contraceptives practically does not exist, except on a small scale in the settled community. Every woman, following the Koranic teachings, weans her child exactly at the age of 2 years, which obviously leads to the spacing of births. In rather rare situations, coitus interruptus is practised.

Fishing for a Career: Alternative Livelihoods and the Hardheaded Art of Academic Failure

2017 ◽  
Vol 2 (2) ◽  
pp. 155-167
Author(s):  
Deb Cleland
Keyword(s):  
East Asia ◽  
Marine Ecosystem ◽  
Academic Failure ◽  
Work Life ◽  
Small Scale ◽  
South East Asia ◽  
Alternative Livelihoods ◽  
Alternative Livelihood ◽  
The World ◽  
History Of

Charting the course: The world of alternative livelihood research brings a heavy history of paternalistic colonial intervention and moralising. In particular, subsistence fishers in South East Asia are cyclical attractors of project funding to help them exit poverty and not ‘further degrade the marine ecosystem’ (Cinner et al. 2011), through leaving their boats behind and embarking on non-oceanic careers. What happens, then, when we turn an autoethnographic eye on the livelihood of the alternative livelihood researcher? What lexicons of lack and luck may we borrow from the fishers in order to ‘render articulate and more systematic those feelings of dissatisfaction’ (Young 2002) of an academic’s life’s work and our work-life? What might we learn from comparing small-scale fishers to small-scale scholars about how to successfully ‘navigate’ the casualised waters of the modern university? Does this unlikely course bring any ideas of ‘possibilities glimmering’ (Young 2002) for ‘exiting’ poverty in Academia?

scholarly journals Risk Factors for Maternal Chagas Disease and Vertical Transmission in a Bolivian Hospital

2020 ◽  
Author(s):  
Melissa D Klein ◽  
Freddy Tinajeros ◽  
María del Carmen Menduiña ◽  
Edith Málaga ◽  
Beth J Condori ◽  
...  
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Chagas Disease ◽  
Vertical Transmission ◽  
Quantitative Polymerase Chain Reaction ◽  
Diagnostic Testing ◽  
Rapid Test ◽  
Diagnostic Techniques ◽  
Lower Education Level ◽  
History Of

Abstract Background Vertical transmission of Trypanosoma cruzi infection accounts for a growing proportion of new cases of Chagas disease. Better risk stratification is needed to predict which women are more likely to transmit the infection. Methods This study enrolled women and their infants at the Percy Boland Women’s Hospital in Santa Cruz, Bolivia. Pregnant women were screened for Chagas disease by rapid test and received confirmatory serology. Infants of seropositive mothers underwent diagnostic testing with quantitative polymerase chain reaction (qPCR). Results Among 5,828 enrolled women, 1,271 (21.8%) screened positive for Chagas disease. Older maternal age, family history of Chagas disease, home conditions, lower education level, and history of living in a rural area were significantly associated with higher adjusted odds of maternal infection. Of the 1,325 infants of seropositive mothers, 65 infants (4.9%) were diagnosed with congenital Chagas disease. Protective factors against transmission included Cesarean delivery (adjusted OR [aOR]: 0.60, 95% CI: 0.36-0.99) and family history of Chagas disease (aOR: 0.58, 95% CI: 0.34-0.99). Twins were significantly more likely to be congenitally infected than singleton births (OR: 3.32, 95% CI: 1.60-6.90). Among congenitally infected infants, 32.3% had low birth weight, and 30.8% required hospitalization after birth. Conclusions Although improved access to screening and qPCR increased the number of infants diagnosed with congenital Chagas disease, many infants remain undiagnosed. A better understanding of risk factors and improved access to highly sensitive and specific diagnostic techniques for congenital Chagas disease may help improve regional initiatives to reduce disease burden.

‘It’s Not a Reservoir; It’s Valuable Agricultural Land’: Controlled Use of Water and Deliberate Flooding in Lincolnshire

2021 ◽  
Author(s):  
Jane Rowling
Keyword(s):  
Water Retention ◽  
Agricultural Land ◽  
Small Scale ◽  
Internal Drainage ◽  
Management Planning ◽  
The Public ◽  
Academic Literature ◽  
History Of ◽  
Water Management Planning

The Lincolnshire lowlands owe their existence to a long-term programme of formal and informal drainage, by which the landscape has been managed since the Roman period. The public bodies that have held responsibility for this drainage, namely the Commissions of Sewers followed by the Internal Drainage Boards (IDBs) from 1930, are often perceived as solely aiming to remove water from the land as quickly as possible. Recent water management planning in Lincolnshire has begun to explore the idea of water retention, but, as this article will show, this is not a new idea. Far from keeping water out at all costs, Lincolnshire’s drained, farmed landscape is a porous one, which has benefited from a long history of deliberate, managed flooding and small-scale sacrifice of valuable agricultural land to water. This is a lacuna which exists in both the academic literature, and in the stories people involved in the drainage boards tell about themselves.

Can We See the “Hoplite Revolution” on the Ground? Archaeological Landscapes, Material Culture, and Social Status in Early Greece

Men of Bronze ◽  
2013 ◽  
Author(s):  
Lin Foxhall
Keyword(s):  
Material Culture ◽  
Historical Analysis ◽  
Historical Record ◽  
Eighth Century ◽  
Small Scale ◽  
Site Survey ◽  
Archaic Greece ◽  
History Of ◽  
Small Scale Farmers ◽  
A Site

This chapter considers what a site survey might reveal about the appearance of a new class of small farmers in archaic Greece. It gives a brief history of the discipline and explains the strengths and limitations of using its findings for historical analysis. This study of eight survey projects across Greece, including Boeotia, the Argolid, Laconia, and Pylos, focuses on data for the Geometric through the Hellenistic periods. The chapter suggests that the archaeology tells us a different story than the historical record of citizens, soldiers, and property owners. The survey data show the rise of a densely populated countryside of small-scale farmers neither in the eighth century nor, universally, in the sixth century.

Crafts Traders versus the State

2017 ◽  
Author(s):  
Dillon Mahoney
Keyword(s):  
Local Governments ◽  
New Technologies ◽  
The State ◽  
Small Scale ◽  
British Colonialism ◽  
Starting Point ◽  
Diverse Backgrounds ◽  
Before And After ◽  
History Of ◽  
The Relationship

This chapter traces the development of Kenya’s tourism and handicraft industries from their roots in 20th century British colonialism to provide some of the broader history of Kenya’s tourism and co-operative development, their emergence in Mombasa, and their relationships with local governments. I draw on archival as well as ethnographic data collected just before the 2002 demolition of Mombasa’s roadside kiosks, which form the starting point for the larger longitudinal study. I focus on the array of experiences of Mombasa’s roadside traders of diverse backgrounds as they struggle with the privatization and segregation of urban residential and commercial space both before and after the demolitions. The economy was radically altered as the roadsides were “cleaned” and a new wave of economic formalization characterized the relationship between small-scale businesspeople and the state. For many entrepreneurs invested in the global crafts trade, this was the final straw that pushed them toward new technologies, jumping scales into global markets, and investing in export and wholesale businesses that were not spatially dependent upon a connection to the city center.

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