Risk Factors for Environmental Pollution with Dioxin-Containing Compounds

2020 ◽  
pp. 39-43
Author(s):  
L.A. Nikolaeva ◽  
L.P. Ignatieva ◽  
M.F. Savchenkov
Keyword(s):  
Risk Factors ◽  
High Efficiency ◽  
Daily Intake ◽  
Climatic Conditions ◽  
Positive Sample ◽  
Amine Salt ◽  
Gas Chromatography Mass Spectrometry ◽  
Animal Origin ◽  
Soil Concentration ◽  
Daily Dose

Introduction. It has been demonstrated that the use of 2,4-D herbicide contaminates the environment with polychlorinated compounds, including dioxins. Additional risk factors for population health and the environment include climatic conditions of Siberia, processes of translocation of compounds from soil to plants, their ability to reach the human body along trophic chains and to have a toxic effect. The objective of this study was to analyze the behavior of the 2,4-D herbicide and dioxins in the environment and to justify health risk factors. Materials and methods. We used the method of gas chromatography-mass spectrometry that combines high efficiency of separation of impurities, the possibility of determining their molecular composition, selectivity of recording, and high sensitivity. We used a chromatographic method to determine residual amounts of the 2,4-dichlorophenoxyacetic acid amine salt (2,4-D) in soil, feed, and food of plant and animal origin. The calculation of average and statistical errors of indicators was performed using t-test in MS Excel. Results. Contamination of water of open reservoirs of the Irkutsk Region with the 2,4-D herbicide amine salt was found in concentrations as high as 7.7 μg/L with a positive sample count of 49%. In spring and summer, the water of open reservoirs is also polluted. In soils, the 2,4-D amine salt is immobile, concentrated in the surface layer at the level of 0.42–0.37 mg/kg. The maximum total soil concentration of dioxins reached 1,479 ng/kg exceeding the maximum permissible soil concentration of dioxins by 306 times. The maximum concentration of dioxins in feed was found at the end of the growing season (317–322 ng/kg). Dioxins accumulate in fat-containing food; thus, measured dioxin concentrations in butter averaged 680.6 ng/kg demonstrating a 10-fold excess of the permissible level. The estimated daily intake of dioxins with food can be as high as 26.2 pg/kg, which is 2.6 times higher than the permissible daily dose. We conducted the environmental and medico-hygienic analysis of outcomes of using the effective herbicide that poses a serious danger to human health due to the possibility of dioxin formation. We identified risk factors and substantiated the daily dose of dioxins for humans as a temporary value.

Potential of Selected Indian Herbs for COVID-19

2020 ◽  
Vol 06 ◽  
Author(s):  
Ravindra Verma ◽  
Vaibhav Misra ◽  
Dileep Tiwari ◽  
Prakash S. Bisen
Keyword(s):  
Risk Factors ◽  
Withania Somnifera ◽  
Epidemiologic Studies ◽  
Climatic Conditions ◽  
Tinospora Cordifolia ◽  
Environmental Threats ◽  
Scientific Databases ◽  
First Case ◽  
Ocimum Tenuiflorum ◽  
Novel Coronavirus

Introduction: Many environmental risk factors are associated with some form of chronic inflammation. The spread of COVID-19 across the world has impacted every one of us. The first case of coronavirus was reported on 30 January 2020 in India originating from China. Study Area: India has a tremendous capacity to deal with the coronavirus outbreak because of its high immunity and climatic conditions. Maintaining social distancing and hand washing is not a sufficient step for preventing COVID-19. Indian system of traditional medicine has a potential worth to enhance immunity, which can resist a novel coronavirus. Material & Methods: A detailed study was carried out by analyzing national and international scientific databases (PubMed, SciFinder, ScienceDirect, Scopus, and Web of Science, Mendeley), thesis, and recognized books. Only Indian herbs with high immunity resistant power were analyzed. Epidemiologic studies with information on COVID-19 risk factors and precautions also considered for study purposes. Results: Some herbs like Ocimum tenuiflorum (Tulsi), Glycyrrhiza glabra (Liquorice), Curcuma domestica Vahl (Turmeric), Tinospora cordifolia (Giloy), Withania somnifera (Ashwagandha), Cinnamon (Dalchini), Shoot of Triticumaestivum Linn. (Wheatgrass), Andrographis paniculata (Kalmegh), can help in boosting immunity for COVID-19 disease. Discussion: Despite the shreds of evidence for the efficacy of these herbs in treating coronavirus induced infections; the proper dose with ideal timing for such interventions needs to verify in clinical trials. Researchers must have to take the privilege to explore the potential of herbs to reduce such epidemics of environmental threats.

scholarly journals Biodegradation and metabolic pathway of fenvalerate by Citrobacter freundii CD-9

AMB Express ◽  
2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Jie Tang ◽  
Dan Lei ◽  
Min Wu ◽  
Qiong Hu ◽  
Qing Zhang
Keyword(s):  
Environmental Pollution ◽  
Environmental Remediation ◽  
High Efficiency ◽  
Mass Spectrometry Analysis ◽  
Gas Chromatography Mass Spectrometry ◽  
Citrobacter Freundii ◽  
16S Rrna Sequence ◽  
Intracellular Enzyme ◽  
Pyrethroid Insecticides ◽  
Spectrometry Analysis

Abstract Fenvalerate is a pyrethroid insecticide with rapid action, strong targeting, broad spectrum, and high efficiency. However, continued use of fenvalerate has resulted in its widespread presence as a pollutant in surface streams and soils, causing serious environmental pollution. Pesticide residues in the soil are closely related to food safety, yet little is known regarding the kinetics and metabolic behaviors of fenvalerate. In this study, a fenvalerate-degrading microbial strain, CD-9, isolated from factory sludge, was identified as Citrobacter freundii based on morphological, physio-biochemical, and 16S rRNA sequence analysis. Response surface methodology analysis showed that the optimum conditions for fenvalerate degradation by CD-9 were pH 6.3, substrate concentration 77 mg/L, and inoculum amount 6% (v/v). Under these conditions, approximately 88% of fenvalerate present was degraded within 72 h of culture. Based on high-performance liquid chromatography and gas chromatography-mass spectrometry analysis, ten metabolites were confirmed after the degradation of fenvalerate by strain CD-9. Among them, o-phthalaldehyde is a new metabolite for fenvalerate degradation. Based on the identified metabolites, a possible degradation pathway of fenvalerate by C. freundii CD-9 was proposed. Furthermore, the enzyme localization method was used to study CD-9 bacteria and determine that its degrading enzyme is an intracellular enzyme. The degradation rate of fenvalerate by a crude enzyme solution for over 30 min was 73.87%. These results showed that strain CD-9 may be a suitable organism to eliminate environmental pollution by pyrethroid insecticides and provide a future reference for the preparation of microbial degradation agents and environmental remediation.

scholarly journals OP0133 THE PREVALENCE AND RISK FACTORS OF RETINAL TOXICITY ASSOCIATED WITH LONG-TERM HYDROXYCHLOROQUINE USE

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 77-78
Author(s):  
S. Do ◽  
J. H. Du ◽  
J. X. An ◽  
J. Wang ◽  
A. Lin
Keyword(s):  
Risk Factors ◽  
Cumulative Dose ◽  
Daily Intake ◽  
Retinal Toxicity ◽  
Factors Associated ◽  
Duration Of Therapy ◽  
Increased Risk ◽  
Hydroxychloroquine Retinopathy ◽  
Risk Of Retinopathy

Background:Hydroxychloroquine (HCQ) is commonly used for the treatment of various autoimmune diseases. The medication is generally well-tolerated. However, long-term use after 5 years may increase the risk of retinopathy. One study in 2014 has demonstrated the risk can be as high as 7.5%. Optical Coherence Tomography (OCT) has become a major modality in screening retinopathy.Objectives:To evaluate the prevalence of retinal toxicity among patients using hydroxychloroquine and to determine various risk factors associated with hydroxychloroquine-associated retinal toxicity.Methods:We performed a retrospective chart review on a cohort of adult patients with long-term use (≥ 5 years cumulative) of HCQ between January 1st, 2011 to December 31st, 2018 from the Kaiser Permanente San Bernardino County and Riverside medical center areas in Southern California, USA. Patients were excluded if they had previously been diagnosed with retinopathy prior to hydroxychloroquine use, were deceased, or had incomplete OCT exam. Our primary endpoint was the prevalence of patients who developed retinal toxicity detected by OCT, and later confirmed by retinal specialist. Potential risk factors (age, duration of therapy, daily consumption per actual body weight, cumulative dose, confounding diseases and medication) for developing retinopathy were also evaluated. Univariable and multivariable logistic regression analyses were used to determine risk factors associated with retinal toxicity.Results:Among 676 patients exposed to more than 5 years of HCQ, the overall prevalence of retinal toxicity was 6.8%, and ranged from 2.5% to 22.2% depending on the age, weight-based dosing, duration of use and cumulative dose. Duration of therapy for 10 years or more increased risk of retinopathy by approximately 5 to 19 folds. Similarly, weight-based dose of 7 mg/kg/day or greater was assciated with increased risk of retinopathy by approximately 5 times. Patients with cumulative dose of 2000 grams or more had greater than 15 times higher risk of developing retinopathy. Duration of use for10 years or more (odd ratio 4.32, 95% CI 1.99 – 12.49), age (odd ratio 1.04; 95% CI 1.01 - 1.08), cumulative dose of more than 1500 g (odd ratio 7.4; 95% CI 1.40 – 39.04) and atherosclerosis of the aorta (odd ratio 2.59; 95% CI, 1.24 – 5.41) correlated with higher risk of retinal toxicity.Conclusion:The overall prevalence of retinopathy was 6.8%. Regular OCT screening, especially in patients with hydroxychloroquine use for more than 10 years, daily intake > 7 mg/kg, or cumulative dose > 1500 grams is important in detecting hydroxychloroquine-associated retinal toxicityReferences:[1]Hobbs HE. Sorsby A, & Freedman A. Retinopathy Following Chloroquine Therapy. The Lancet. 1959; 2(7101): 478-480.[2]Levy, G. D., Munz, S. J., Paschal, J., Cohen, H. B., Pince, K. J., & Peterson, T. Incidence of hydroxychloroquine retinopathy in 1,207 patients in a large multicenter outpatient practice. Arthritis & Rheumatism: 1997; 40(8): 1482-1486.[3]Ding, H. J., Denniston, A. K., Rao, V. K., & Gordon, C. Hydroxychloroquine-related retinal toxicity. Rheumatology. 2016; 55(6): 957-967.[4]Stelton, C. R., Connors, D. B., Walia, S. S., & Walia, H. S. Hydrochloroquine retinopathy: characteristic presentation with review of screening. Clinical rheumatology. 2013; 32(6): 895-898.[5]Marmor, M. F., Kellner, U., Lai, T. Y., Melles, R. B., & Mieler, W. F. Recommendations on screening for chloroquine and hydroxychloroquine retinopathy (2016 revision). Ophthalmology. 2016; 123(6): 1386-1394.[6]Melles, R. B., & Marmor, M. F. The risk of toxic retinopathy in patients on long-term hydroxychloroquine therapy. JAMA ophthalmology. 2014; 132(12): 1453-1460.Disclosure of Interests:None declared

scholarly journals Soil and Leaf Nutrients Drivers on the Chemical Composition of the Essential Oil of Siparuna muricata (Ruiz & Pav.) A. DC. from Ecuador

Molecules ◽  
2021 ◽  
Vol 26 (10) ◽  
pp. 2949
Author(s):  
Juan I. Burneo ◽  
Ángel Benítez ◽  
James Calva ◽  
Pablo Velastegui ◽  
Vladimir Morocho
Keyword(s):  
Gas Chromatography ◽  
Chemical Composition ◽  
Secondary Metabolites ◽  
Essential Oil ◽  
Chemical Elements ◽  
Climatic Conditions ◽  
Gas Chromatography Mass Spectrometry ◽  
Chemical Compositions ◽  
Leaf Nutrients ◽  
First Time

Chemical compositions of plants are affected by the initial nutrient contents in the soil and climatic conditions; thus, we analyzed for the first time the effects of soil and leaf nutrients on the compositions of the essential oils (EOs) of Siparuna muricata in four different localities in Ecuador. EOs were obtained by hydrodistillation and analyzed by gas chromatography/mass spectrometry (GC/MS) and a gas chromatography/flame ionization detector (GC/FID). Enantiomeric distribution by GC/MS was determined, modifying the enantiomeric separation of β-pinene, limonene, δ-elemene, β-bourbonene, cis-cadina-1 (6), 4-diene and atractylone. A total of 44 compounds were identified. The most representative for L1 were guaiol, atractylone and 4-diene; for L2, cis-cadina-1(6),4-diene and myrcene; for L3, atractylone, myrcene and germacrene B; and finally, L4 germacrene B, myrcene and cis-cadina-1(6),4-diene. Correlations between soil- leaf chemical elements such as Al, Ca, Fe, Mg, Mn, N and Si in the different localities were significant with chemical composition of the essential oil of Siparuna muricata; however, correlations between soil and leaf K, P, and Na were not significant. Cluster and NMDS analysis showed high dissimilarity values of secondary metabolites between four localities related with changes in soil- leaf nutrients. Thus, the SIMPER routine revealed that not all secondary metabolites contribute equally to establishing the differences in the four localities, and the largest contributions are due to differences in guaiol, cis-cadina-1(6),4-diene, atractylone and germacrene. Our investigation showed for the first time the influences of altitude and soil- leaf chemical elements in the chemical composition of the EOs of S. muricata.

scholarly journals Chemical Composition, Allelopathic, Antioxidant, and Anti-Inflammatory Activities of Sesquiterpenes Rich Essential Oil of Cleome amblyocarpa Barratte & Murb.

Plants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1294
Author(s):  
Ahmed M. Abd-ElGawad ◽  
Abdelbaset M. Elgamal ◽  
Yasser A. EI-Amier ◽  
Tarik A. Mohamed ◽  
Abd El-Nasser G. El Gendy ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Climatic Conditions ◽  
Chemometric Analysis ◽  
Gas Chromatography Mass Spectrometry ◽  
Authentic Materials ◽  
Dactyloctenium Aegyptium ◽  
Hexahydrofarnesyl Acetone ◽  
Ic50 Values ◽  
Anti Inflammatory

The integration of green natural chemical resources in agricultural, industrial, and pharmaceutical applications allures researchers and scientistic worldwide. Cleome amblyocarpa has been reported as an important medicinal plant. However, its essential oil (EO) has not been well studied; therefore, the present study aimed to characterize the chemical composition of the C. amblyocarpa, collected from Egypt, and assess the allelopathic, antioxidant, and anti-inflammatory activities of its EO. The EO of C. amblyocarpa was extracted by hydrodistillation and characterized via gas chromatography–mass spectrometry (GC-MS). The chemometric analysis of the EO composition of the present studied ecospecies and the other reported ecospecies was studied. The allelopathic activity of the EO was evaluated against the weed Dactyloctenium aegyptium. Additionally, antioxidant and anti-inflammatory activities were determined. Forty-eight compounds, with a prespondence of sesquiterpenes, were recorded. The major compounds were caryophyllene oxide (36.01%), hexahydrofarnesyl acetone (7.92%), alloaromadendrene epoxide (6.17%), myrtenyl acetate (5.73%), isoshyobunone (4.52%), shyobunol (4.19%), and trans-caryophyllene (3.45%). The chemometric analysis revealed inconsistency in the EO composition among various studied ecospecies, where it could be ascribed to the environmental and climatic conditions. The EO showed substantial allelopathic inhibitory activity against the germination, seedling root, and shoot growth of D. aegyptium, with IC50 values of 54.78, 57.10, and 74.07 mg L−1. Additionally, the EO showed strong antioxidant potentiality based on the IC50 values of 4.52 mg mL−1 compared to 2.11 mg mL−1 of the ascorbic acid as standard. Moreover, this oil showed significant anti-inflammation via the suppression of lipoxygenase (LOX) and cyclooxygenases (COX1, and COX2), along with membrane stabilization. Further study is recommended for analysis of the activity of pure authentic materials of the major compounds either singularly or in combination, as well as for evaluation of their mechanism(s) and modes of action as antioxidants or allelochemicals.

Risk of Retinal Toxicity in Longterm Users of Hydroxychloroquine

2017 ◽  
Vol 44 (11) ◽  
pp. 1674-1679 ◽  
Author(s):  
Ji-Won Kim ◽  
Yoon Young Kim ◽  
Hwajeong Lee ◽  
Sung-Hoon Park ◽  
Seong-Kyu Kim ◽  
...  
Keyword(s):  
Risk Factors ◽  
Kidney Disease ◽  
Fundus Autofluorescence ◽  
Binary Logistic Regression ◽  
Field Testing ◽  
Retinal Toxicity ◽  
Binary Logistic Regression Analysis ◽  
Visual Field Testing ◽  
Daily Dose ◽  
Study Participants

Objective.Several studies have reported risk factors for hydroxychloroquine (HCQ) retinal toxicity, but data are limited for patients of Asian ancestry. The aim of this study was to investigate the rate of and factors for HCQ retinal toxicity in the Korean population.Methods.There were 123 patients enrolled in this study who were using or had used HCQ. Retinal toxicity was detected using spectral domain optical coherence tomography, fundus autofluorescence, multifocal electroretinography, and automated visual field testing. Binary logistic regression analysis was performed to identify factors associated with HCQ retinal toxicity.Results.Mean duration of HCQ use and mean HCQ dose in study participants was 10.1 years and 6.4 mg/kg, respectively. We found 17 patients (13.8%) with HCQ retinal toxicity among 123 patients. Patients with retinal toxicity took HCQ ranging from 6.7–21.9 years and daily dosage ranging from 4.9–9.1 mg/kg. Only 1 patient had retinal toxicity among patients with daily dose < 5.0 mg/kg. These factors increased the risk of HCQ retinal toxicity: longer duration of HCQ use [adjusted OR (aOR) = 4.71, 95% CI 2.18–10.15 for duration of HCQ use in 5-yr increments], higher daily HCQ dose (aOR = 3.34, 95% CI 1.03–10.80 for daily HCQ dose in 100-mg increments), and the presence of kidney disease (aOR = 8.56, 95% CI 1.15–64.00).Conclusion.HCQ retinal toxicity is associated with duration of HCQ use, daily HCQ dose, and presence of kidney disease. Proper dosing of maximum 5 mg/kg and regular screening according to risk factors are important in HCQ use.

scholarly journals Prevalence, Risk Factors, and Antibiogram of Nontyphoidal Salmonella from Beef in Ambo and Holeta Towns, Oromia Region, Ethiopia

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Endrias Zewdu Gebremedhin ◽  
Gezahegn Tafesse Soboka ◽  
Bizunesh Mideksa Borana ◽  
Lencho Megersa Marami ◽  
Edilu Jorga Sarba ◽  
...  
Keyword(s):  
Risk Factors ◽  
Food Safety ◽  
Antimicrobial Susceptibility ◽  
Multidrug Resistant ◽  
Animal Origin ◽  
Diffusion Method ◽  
Isolation And Identification ◽  
Disk Diffusion Method ◽  
Cross Sectional ◽  
Food Of Animal Origin

Background. Salmonella has been recognized as a major cause of food-borne illness associated with the consumption of food of animal origin. The present cross-sectional study was conducted from December 2017 to May 2018 in Ambo and Holeta towns to assess the prevalence, risk factors, and antimicrobial susceptibility patterns of nontyphoidal Salmonella isolates from raw beef samples from abattoirs, butchers, and restaurants in Ambo and Holeta towns, Oromia region, Ethiopia. Methods. A total of 354 beef samples were collected from abattoirs, butchers, and restaurants. Salmonella isolation and identification were carried out using standard bacteriological methods recommended by the International Organization for Standardization. Antimicrobial susceptibility testing was performed using the disk diffusion method. Besides, a structured questionnaire was used to collect sociodemographic data and potential risk factors for contamination of meat. Chi-square tests and logistic regression were used for data analyses. Results. Of the total 354 meat samples examined, 20 (5.7%, 95% confidence interval (CI): 3.5–8.6) were positive for Salmonella. Two serotypes belonging to S. typhimurium (11 isolates) and I:4,5,12: i:- (9 isolates) were identified. The Salmonella detection rate in abattoirs, butchers, and restaurants was 4.2% (5/118), 8.5% (10/118), and 4.2% (5/118), respectively. The antimicrobial susceptibility test showed that 40%, 30%, and 20% of the Salmonella isolates were resistant to azithromycin, amoxicillin, and ceftriaxone, respectively. The odds of Salmonella isolation when meat handlers are illiterate were 7.8 times higher than those when they are educated to the level of secondary and above ( P = 0.032 ). Similarly, the likelihood of Salmonella isolation was 6.3 and 7.6 times higher among workers of butcher and restaurants, respectively, who had no training ( P = 0.003 ) and no knowledge ( P = 0.010 ) on food safety and hygiene. Conclusions. The study showed widespread multidrug-resistant Salmonella isolates in the study areas. Therefore, raw meat consumption and indiscriminate use of antimicrobial drugs should be discouraged. Provision of food safety education for meat handlers and further surveillance of antimicrobial-resistant isolates are suggested.

SIGNIFICANT ASPECTS OF EPIDEMIOLOGY, RISK FACTORS AND TREATMENT OF VARICOSE VEINS

2020 ◽  
pp. 320-328
Author(s):  
O.F. SOLIEV ◽  
◽  
D.D. SULTANOV ◽  
S.P. KURBANO ◽  
N.R. KURBANOV ◽  
...  
Keyword(s):  
Risk Factors ◽  
Optical Fibers ◽  
High Efficiency ◽  
Varicose Veins ◽  
Laser Wavelength ◽  
Comprehensive Treatment ◽  
Literature Analysis ◽  
Pregnancy And Childbirth ◽  
Laser Ablation Technique ◽  
Significant Factors

The literature review focuses on the significant aspects of epidemiology, analysis of risk factors and modern principles of surgical treatment of varicose veins. Literature data show that considering pathology in recent years has a tendency to increase the frequency and the significant factors at risk of its development are the inheritance, overweight, as also pregnancy and childbirth of two or more. In recent years, new thermal catheter techniques have become more frequent in the treatment of varicose veins, which demonstrate their advantages and high efficiency. The literature analysis shows that the use of a 1470 nm laser wavelength with a radial type of optical fibers has the highest coagulating effect compared to other types of laser. The authors of the article provided detailed coverage of the endovascular laser ablation technique, showing its advantages over other methods, and its role and place in the comprehensive treatment of the varicose veins.

INFLUENCE OF INSECTICIDES ON PRODUCTIVITY IN RAPE CROPS IN AKMOLA REGION

2021 ◽  
Author(s):  
М.Н.Сертек,Ш.Ш. Бекенова,А.П.Науанова, З.Ш Сулейменова
Keyword(s):  
High Efficiency ◽  
Plant Protection ◽  
Growing Season ◽  
Plant Protection Products ◽  
Steppe Zone ◽  
Climatic Conditions ◽  
Ordinary Chernozem ◽  
Forest Steppe ◽  
Biological Effectiveness ◽  
Harmful Organisms

According to the results of research on the phytosanitary status of rapeseed on ordinary Chernozem of the forest-steppe zone of the Akmola region, the species composition of pests was determined. Danadim power, Zolone 35% KE, Decis Expert were used against pests of this rapeseed. Indicators of biological effectiveness in the use of insecticides against pests ranged from 78-95%.The article discusses the biological and economic effectiveness of insecticides used against the main pests of rapeseed. Treatment of cruciferous rape beetle, rapeseed sawfly and cruciferous bug with Decis Expert insecticide (0.075 l/ha) showed high efficiency during the growing season. The use of plant protection products against a complex of harmful organisms showed that, depending on the prevailing climatic conditions, the yield increased to 1.3 c/ha, and the maximum - to 1.9 c/ha. Thus, according to the biological effectiveness of insecticides used against pests, the productDecis Expert showed high results in all pests. On the Cruciferous rape beetle it was 85.7%, in the turnip sawfly – 93.5%, in the cruciferous bug – 81.9%.

scholarly journals Prevalensi dan Faktor Risiko Paramphistomiasis pada Sapi Bali di Distrik Prafi, Kabupaten Manokwari, Provinsi Papua Barat (PREVALENCE AND RISK FACTORS OF PARAMPHISTOMIASIS IN BALI CATTLE IN PRAFI DISTRICT, MANOKWARI REGENCY, WEST PAPUA PROVINCE)

2018 ◽  
Vol 19 (1) ◽  
pp. 91 ◽  
Author(s):  
Purwaningsih Purwaningsih ◽  
Noviyanti Noviyanti ◽  
Rizki Pratama Putra
Keyword(s):  
Risk Factors ◽  
Animal Feed ◽  
Sampling Technique ◽  
Positive Sample ◽  
Bivariate Analysis ◽  
Chi Square ◽  
West Papua ◽  
Bali Cattle ◽  
Papua Barat ◽  
Livestock Productivity

Paramphistomiasis is a parasiter disease caused by an Paramphistomum sp worms infection. The disease can cause a considerable decline in livestock productivity, therefore it is catagorized as one of economic affected diseases. The aims of this research were to determine the prevalence and distribution of paramphistomiasis in Bali cattle in Prafi District of Manokwari Regency, West Papua Province; and to identify some of the risk factors that associated with the paramphistomiasis prevalence. The research was done between February and March 2016. The feces samples were taken from 369 cattles perrectal were chosen by using proportional random sampling technique at village level. A total of 127 farmer respondents were interviewed. The feces samples were examined with sedimentation test to identify the existence eggs of Paramphistomum sp. based on their morphology. The data were analyzed in univariate to obtain the prevalence by dividing the number of positive sample with the number of samples inspected multiplied by 100%. Then, bivariate analysis was performed by using chi square (c2), and odds ratio (OR). The distribution of paramphistomiasis in Bali cattle that rearing in Prafi District has prevalence value in each village: Udapi Hilir, Desay, Aimasi, and Prafi Mulya was 14.74%; 12.04%; 9.18% and 1.48% respectively. While the prevalence of paramphistomiasis in bali cattle in the Prafi District was 10.03%. Factors of rearing manajemen, such as: combined shed with calve (OR=4.525) and sources of animal feed that taken from the grounds of the house and rice land (OR=4.955) showed a significant influence (P<0.05) on the risk of paramphistomiasis infection.

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