scholarly journals CHROMNIUM PICLONAT EFFECTS IN DIET OF MALE RABBITS EXPOSED TO HEAT STRESS ON SOME PRODUCTIVE TRAITS AND BLOOD SERUM PARAMETERS

2019 ◽  
Vol 50 (4) ◽  
Author(s):  
Hashem & Al-Saadi
Keyword(s):  
Body Weight ◽  
Heat Stress ◽  
Basal Diet ◽  
Positive Control ◽  
Feed Additives ◽  
Positive Control Group ◽  
Control Group ◽  
Serum Parameters ◽  
Performance Traits ◽  
Productive Traits

current study was conducted to determine the effects of Chromium piclonat supplementation on some  productive  traits and serum parameters of male rabbit exposed to heat stress by used electric heaters  ,twenty four male rabbits were randomly divided into four groups 6 for each, first group put in normal suitable climate condition based diet without additional Chromium and kept as positive control group , while The other  three groups exposed to heat stress  , the basal diet was consisted of 0, 300 , and 500 ppb of Chromium piclonate  respectively as a feed additives . All rabbit received feed and water ad libitum, the results showed  that there were Increasing organic Cr supplementation 300 and 500 pbb  of two treated groups resulted in an increase in body weight compared with negative and positive control group , the  serum glucose and cortisone hormone concentrations of both treated groups were decrease, as dietary Cr level increased (P<0.05), but Cr supplementation did not affect total protein,  albumen and globulin. These data indicated that organic Cr supplementation increased some performance traits, particularly body weight production and decreased in glucose and cortisone hormone while there were not significant effect in the total of serum protein,  Albumin and globulin ,it can be concluded that adding chromium piclonat in dose 300,500pbb in diet of rabbits during  hot periods has a benefits to overcome deterioration in some performance traits  related to oxidative stress results from  heat stress.

scholarly journals In VivoAntiplasmodial and Analgesic Effect of Crude Ethanol Extract ofPiper guineenseLeaf Extract inAlbinoMice

Scientifica ◽  
2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
A. Y. Kabiru ◽  
G. F. Ibikunle ◽  
D. A. Innalegwu ◽  
B. M. Bola ◽  
F. M. Madaki
Keyword(s):  
Body Weight ◽  
Analgesic Efficacy ◽  
Ethanol Extract ◽  
Positive Control ◽  
Positive Control Group ◽  
Control Group ◽  
Piper Guineense ◽  
Standard Drug ◽  
Analgesic Effects ◽  
Dose Dependent

Antiplasmodial and analgesic effects of crude ethanol extract ofPiper guineensewas investigated in mice. The antiplasmodial and analgesic efficacy of the extract was judged on its ability to reduce parasitemia and writhing, respectively, in mice. The antiplasmodial screening involved treating infected mice with 200, 400, and 600 mg/kg body weight of extract while the positive control group was given standard artesunate drug. The analgesic test was carried out by administering 1000, 1500, and 2000 mg/kg body weight of extract to three groups of healthy mice, respectively, after induction of pain with 0.75% acetic acid. The positive control group was given aspirin drug. Parasitemia was reduced by 28.36%, 43.28%, and 62.69% in a dose-dependent pattern in the curative test which was significantly different (P<0.05) from 96.03% of the standard drug. The reduction of writhing by mice given the extract was also dose-dependent (36.29, 45.43, and 59.07%). Aspirin drug was however more effective (86.36%). The extract was safe at 2000 mg/kg body weight. Phytochemical screening revealed the presence of flavonoids, tannins, phlobatannins, terpenoids, and coumarins. Result obtained in this study demonstrated the efficacy of ethanol extract ofPiper guineenseas an antiplasmodial and analgesic agent.

scholarly journals Administration of garlic and neem in broiler diet for safe meat production

2020 ◽  
Vol 48 (2) ◽  
pp. 116-126
Author(s):  
R Islam ◽  
MM Hossain ◽  
F Nargis ◽  
ME Hossain
Keyword(s):  
Body Weight ◽  
Basal Diet ◽  
Feed Additives ◽  
The Body ◽  
The Other ◽  
Control Group ◽  
Meat Production ◽  
Broiler Chicks ◽  
Treatment Groups ◽  
Broiler Production

This study was conducted to observe the effect of different administration method of garlic and neem on growth performances, feed efficiency and serum biochemical parameters for safe broiler production. The experiment was done for a period of 32 days with 384 one-day-old straight run broiler chicks. The broiler chicks were divided into six groups each of 64 birds and replicated to four subgroups each of 16 birds. The dietary groups were; control (basal diet; no additives), antibiotic (basal diet + antibiotic), garlic in feed (basal diet + 0.25% garlic powder), garlic in water (basal diet + garlic extracts), neem in feed (basal diet + 0.25% neem powder) and neem in water (basal diet + neem extracts). Results showed that the body weight and body weight gain increased significantly (P<0.05) in both the garlic and neem groups compared to the control group. Feed intake was not different (P>0.05) among the treatment groups. Garlic in feed and water and neem in feed groups showed better FCR (P<0.05) compared to the other treatment groups. There were no significant (P>0.05) difference in meat yield, bone development and dressing parameters except head and gizzard in different dietary groups. Supplementation of garlic with feed and water significantly (P<0.05) decrease cholesterol, triglyceride and LDL compared to the other groups. However, both the garlic and neem groups showed numerically higher HDL compare to the control group. There were no 0significant (P>0.05) differences in serum glucose and GPT among different treatment groups. GOT was significantly (P<0.05) lower in neem groups than that of garlic and antibiotic groups. Additive groups showed higher profitability than control group. Based on the results of the study, it may be suggested that the garlic and neem could be used both in feed and water as potential feed additives for safe broiler production. Bang. J. Anim. Sci. 2019. 48 (2): 116-126

scholarly journals Ameliorative Effect of Ethanolic Extract of Petroselinum Crispum Against Gentamicin-Induced Nephrotoxicity in Rabbits Male

2020 ◽  
Vol 13 (2) ◽  
Author(s):  
Sarah Hussain ◽  
Mariam Kadhem
Keyword(s):  
Body Weight ◽  
Clinical Signs ◽  
Ethanolic Extract ◽  
Negative Control Group ◽  
Positive Control ◽  
Negative Control ◽  
The Body ◽  
Positive Control Group ◽  
Control Group ◽  
Petroselinum Crispum

The experiment was conducted to investigate the protective effect of Petroselinum crispum leave extracted against gentamicin-induced nephrotoxicity in male rabbits by studying the body weight, clinical signs, haematological and biochemical parameters, gross lesion and histopathological changes. Twenty four rabbits male were used and divided into 4 groups. Group 1: rabbits served as a negative control, received distilled water 1 ml(orally). Group 2: rabbits served as a positive control group, received gentamicin at a dose of 80 mg/kg/day intramuscular for 15 days. Group 3: rabbits received gentamicin at a dose of 80 mg/kg/day then after one hour treated with ethanolic extract of Petroselinum crispum at dose 125 mg/kg orally for 15 days. Group 4: rabbits received gentamicin at a dose of 80 mg/kg/day then after one hour treated with ethanolic extract of Petroselinum crispum at dose 250 mg/kg orally for 15 days.The results of the gentamicin treated group( positive control group) showed clinical signs such as loss of body weight, loss of appetite and rough hair with hematuria. The body weight a significantly declined (p≤ 0.05) compared other groups. There was a significant decrease (p≤ 0.05) in WBC count, lymphocyte, GSH, SOD, CAT, and GPX levels, while it recorded a significant increase (p≤0.05) in weights of the kidneys, neutrophils, creatinine, urea, and MDA. Histological studies showed several kidney pathological changes such as pale colour, enlargement in size and weight and easy from detaching as opposed to negative control group. On the other hand, the group treated with ethanolic extractof Petroselinum crispum at dose 125 mg/kg induced improved of parameters as recorded significant increased(P ≤ 0.05) in body weight, WBC count, lymphocyte, GSH, SOD, CAT, and GPX, while significant decreased (P ≤ 0.05) in weights of the kidneys, neutrophils, creatinine, urea, and MDA compared with the positive control group whereas rabbits treated with ethanolic extract of Petroselinum crispum at dose 250 mg/kg restored the parameters and histological changes of the kidney to near normal status compared with the negative control group. These results showed that the dose-detected Petroselinum crispum extract (250mg / kg) acts as potential curative effect against gentamicin-induced nephrotoxicity in male rabbits.

scholarly journals ANTIOXIDANT AND HEPATOPROTECTIVE EFFECT OF QUERCUS ILEX LEAVES EXTRACT IN ETHANOL INDUCED LIVER DAMAGE IN WISTAR RATS

2020 ◽  
pp. 26-31
Author(s):  
RENU MALIK ◽  
K. G. SINGHAL
Keyword(s):  
Body Weight ◽  
Wistar Rats ◽  
Quercus Ilex ◽  
Chemical Constituents ◽  
Liver Weight ◽  
Positive Control ◽  
Positive Control Group ◽  
Ethanol Administration ◽  
Control Group ◽  
Standard Drug

Objective: This study was undertaken to investigate the hepatoprotective and antioxidant activity of Quercus ilex leaves extract (QILE) on ethanol-induced toxicity in Wistar rats. Methods: Hepatotoxicity was induced by administering ethanol (40%) at a dose of 7.9 gm/kg/day; p. o. (1:1 of ethanol in olive oil) for 28 d. Silymarin 100 mg/kg/day; p. o. was used as a standard drug. The whole study was divided into a prophylactic and curative study. In the prophylactic study, the Silymarin and QILE (test drug) 100, 200, and 400 mg/kg Body Weight(BW) given orally one hour before administration of 40% ethanol administration for 28 d. In the curative study, 7 d of treatment of Silymarin and QILE 200 and 400 mg/kg BW was given orally after 28 d of ethanol administration to different groups. Results: Hepatoprotectivity was confirmed by the highly significantly (p<0.001) restoration of elevated biochemical parameters like SGPT, SGOT, ALP, TB, and highly significantly (p<0.001) depleted Albumin and Total protein levels by 200 mg/kg BW QILE in comparison to the positive control group. QILE 200 mg/kg highly significantly (p<0.001) raised the antioxidants by draining the elevated oxidative stress markers in comparison of positive control group. At dose levels QILE 200 mg/kg, significant (p<0.05) protection from loss in body weight and in liver weight was found when the comparison was done with the positive control group. Histopathology revealed that QILE 200 mg/kg reduced the markers of cell necrosis. Conclusion: Present study revealed that Quercus ilex leaves have antioxidant and hepatoprotective activity due to its chemical constituents.

scholarly journals Effects of Propolis on Selected Blood Indicators and Antioxidant Enzyme Activities in Broilers under Heat Stress

2009 ◽  
Vol 78 (1) ◽  
pp. 75-83 ◽  
Author(s):  
Pınar Tatlı Seven ◽  
Seval Yılmaz ◽  
Ismail Seven ◽  
Ibrahim H. Cercı ◽  
Mehmet A. Azman ◽  
...  
Keyword(s):  
Heat Stress ◽  
Vitamin C ◽  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Basal Diet ◽  
Positive Control ◽  
Diet Group ◽  
Control Group ◽  
Antioxidant Enzyme Activities ◽  
Group I

In this study, we investigated the antioxidant activity of ethanol extracts of propolis (EEP) and vitamin C on biochemical indicators and antioxidant enzyme activities of broilers exposed to heat stress (at 34 °C). The experimental groups were as follows: group I (positive control) and group II (control) were fed a basal diet, group III (vitamin C) was fed a basal diet supplemented with 250 mg vitamin C as ascorbic acid/kg, group IV (EEP-0.5) was fed a basal diet supplemented with 0.5 g EEP/kg, group V (EEP-1) was fed a basal diet supplemented with 1 g EEP/kg, group VI (EEP-3) was fed a basal diet supplemented with 3 g EEP/kg. Plasma superoxide dismutase levels of positive control, control, vitamin C, EEP-0.5, EEP-1 and EEP-3 groups were found as 0.34, 1.23, 0.50, 0.90, 0.30 and 0.41 μkat/ml, respectively (p < 0.01). Aspartate transaminase (except for EEP-0.5 and EEP-1 groups) and alkaline phosphatase in the control group were significantly higher than those of positive control, vitamin-C and EEP-3 groups. Malondialdehyde level in plasma, liver and muscle tissues of control group were found significantly (p < 0.05) higher than those of positive control and EEP-3 groups. Catalase activities of blood, liver, kidney and heart were the highest in the control group. Reduced glutathione activities of plasma and liver of all groups were not significantly different from each other, whereas those of muscle, kidney and heart were significantly higher in the control group. Significantly lower levels of glutathione peroxidase were found in blood, liver and kidney tissues of the control group (p < 0.05), whereas those of muscle and heart were similar in all groups. The results of the present study suggest that EEP and specially EEP at the supplemented dose of 3 mg/kg diet might be considered to prevent oxidative stress in the broilers exposed to heat stress.

scholarly journals Dietary supplementation of Neem (Azadirachta indica) leaf extracts improved growth performance and reduced production cost in broilers

2020 ◽  
Vol 13 (6) ◽  
pp. 1050-1055
Author(s):  
Torun Kumar Paul ◽  
Md. Mehedi Hasan ◽  
Md. Anowarul Haque ◽  
Sudipta Talukder ◽  
Yousuf Ali Sarker ◽  
...  
Keyword(s):  
Body Weight ◽  
Azadirachta Indica ◽  
Basal Diet ◽  
Positive Control ◽  
Negative Control ◽  
Control Group ◽  
Broiler Chicks ◽  
Growth Promoter ◽  
Leaf Extracts ◽  
Neem Leaves

Background and Aim: Global trend to remove the antibiotic growth promoter (AGP) from animals contributes to the exploration of successful measures to sustain production and reduces the intestinal diseases in the post-AGP era. Plant extracts, therefore, have been used to improve performance and intestinal health. Here, we conducted a study to evaluate the effects of neem (Azadirachta indica) leaf extracts (NLE) as alternatives to AGPs in broiler chickens. Materials and Methods: Sixty day-old broiler chicks were assigned to 12-floor pens, each stocked with five birds and divided into three treatment groups of four pens per treatment. The groups were: Negative control, basal diet without additives; positive control, basal diet with antibiotics and vitamins; and NLE treated group, basal diet supplemented with 0.1% aqua extract of neem leaves. Results: Overall feed intake was significantly (p≤0.05) highest in the positive control. Higher body weight, higher dressing percentage, and lower feed conversion ratio were observed in birds treated with NLE compared to the negative control group (p≤0.05) but not the positive control group (p>0.05). There was no significant variation in hematology between different groups. Furthermore, the economic evaluation indicated that the NLE treatment was found cheaper than control and antibiotic treatment in cost-benefit analysis. Conclusion: We suggest NLE might be a cheaper alternative to antibiotics in broiler production as indicated by improved body weight and feed efficiency.

scholarly journals Evaluation of Sweet Basil Powder Plant (Ocimum basilicum L.) as a Feed Additives, on the Performance of broilerChicks

2013 ◽  
Vol 37 (1) ◽  
pp. 52-58
Author(s):  
Thair Jawad Kadhim Al-Kelabi
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Feed Intake ◽  
Basal Diet ◽  
Conversion Ratio ◽  
Feed Additives ◽  
Feed Conversion Ratio ◽  
Control Group ◽  
Feed Conversion ◽  
Sweet Basil

The present study was carried out at the Poultry Farm, College of Veterinary Medicine -Baghdad University, for powder sweet basil plant evaluation as feed additives, and its effect on the performance and health of broiler. Three hundred one day old Hubbard broiler chicks were used in this study. Chicks were weighed and randomly divided into 10 treatments groups, with 2 replicates (15chicks each).These groups were fed with the following rations: The 1st group was fed the basal diet (control group).The 2nd,3rd and 4th groups were fed the basal diet+0.3, 0.4 and 0.5 % basil powder for the first 3 weeks only respectively. At the 5th, 6th and 7th groups were fed the same basal diet +0.3, 0.4 and 0.5 % basil powder for the second 3 weeks respectively. While the 8th, 9th and 10th were fed the same basal diet with 0.3, 0.4 and 0.5 % basil powder along the whole six weeks. The experiment was terminated when birds were 6 weeks old. Weight gain, feed intake and feed conversion ratio were measured at the end of first three weeks and also at the end of the experiment. The results revealed that adding sweet basil powder significantly (P< 0.05) increased live body weight, body weight gain and feed conversion ratio as compared with the control, especially on the level 3%, 4%, 5% of Sweet basil powder addition along the whole period of the experiment and There was a significant (P< 0.05) decrease in total feed intake compared with the control group.

scholarly journals Effects of Dietary Supplementation With Clostridium butyricum on the Amelioration of Growth Performance, Rumen Fermentation, and Rumen Microbiota of Holstein Heifers

2021 ◽  
Vol 8 ◽  
Author(s):  
Yang Li ◽  
Yiqiang Wang ◽  
Jingyi Lv ◽  
Xiujing Dou ◽  
Yonggen Zhang
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Basal Diet ◽  
Blood Parameters ◽  
Rumen Fermentation ◽  
Economic Benefits ◽  
Feed Additives ◽  
Clostridium Butyricum ◽  
Control Group ◽  
Molar Proportion

In China, the use of antibiotics growth promoters as feed additives has been banned. The goal of raising dairy heifers is to gain a relatively high body weight on a high-fiber diet at first mating or calving, thus increasing economic benefits. The objective of this experiment was to explore the effects of supplemental Clostridium butyricum (C. butyricum) on growth performance, rumen fermentation and microbiota, and blood parameters in Holstein heifers. Twenty Holstein heifers [mean ± standard deviation (SD); age = 182 ± 4.20 d, body weight = 197.53 ± 5.94 kg, dry matter intake (DMI) = 6.10 ± 0.38 kg] were randomly assigned to one of two diets group for a 42-day feeding period: (1) basal diet (an untreated control group, i.e., the CON group) or (2) basal diet plus daily 2 × 108 (colony-forming unit, CFU) of C. butyricum per kg of DMI per heifer (the CB group). The results demonstrated that C. butyricum supplementation increased the average daily gain from d 21 to 42 and DMI compared to the control group. Supplementation with C. butyricum significantly decreased the molar proportion of acetate and the acetate to propionate ratio but increased the molar proportion of butyrate and propionate. Compared with the control group, the relative abundance of Butyrivibrio fibrisolvens, Ruminococcus albus, Ruminobacter amylophilus, Ruminococcus flavefaciens, and Streptococcus bovis increased during the trial period in the CB group. However, C. butyricum had no significant effect on the blood parameters in Holstein heifers. In conclusion, these results show that feeding C. butyricum can improve growth performance and rumen fermentation without any negative impact on blood parameters in Holstein heifers.

scholarly journals The effect of Averrhoa bilimbi stem extract on the blood glucose level of white rats induced by alloxan

2017 ◽  
Vol 14 (2) ◽  
pp. 56-62
Author(s):  
CAHYANING GUSTI AGRIANI ◽  
KISRINI KISRINI ◽  
RUBEN DHARMAWAN
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Positive Control ◽  
Drug Group ◽  
Positive Control Group ◽  
Control Group ◽  
White Rats ◽  
Stem Extract

Agriani CN, Kisrini, Dharmawan R. 2016. The effect of Averrhoa bilimbi stem extract on the blood glucose level of white rats induced by alloxan. Biofarmasi 14: 56-62. The purpose of this research is to find out the effect of belimbing wuluh stem (Averrhoa bilimbi L.) extract due to the blood glucose level in white rats (Rattus norvegicus) induced by alloxan. This research is a laboratory experiment using experimental control group pre-post test design. Subjects of this research are 25 white male rats (Rattus norvegicus), 2 months of age and 200 g of body weight. Subjects were divided into five groups. All groups were induced by 25 mg/200 g body weight/day of alloxan for three days. On the day of fourth, blood sample was collected from orbital vein of white rats for the measurement of the first blood glucose level (T1). Furthermore, the positive control group received 12,6 mg/200 g body weight/day of metformin, then the first, second, and third group received of each 25, 50, and 100 mg/200 g body weight/day of belimbing wuluh stem extract. On the fifteenth day of treatment, blood samples were collected again from the orbital vein of white rats for the measurement of the second blood glucose level (T2). The measurement of blood glucose was using spectrophotometer with the Glucose GOD PAP method. Then the data were analyzed by using One way ANOVA. Blood glucose rate after induction has subtracted from blood glucose rate after drug given. After that the data would be change in to mean data that represents as: negative control group = 24,4; positive control group 103,4; first given drug group = 83,4; second given drug group = 102,4; and third given drug group = 102,2 (in mg/100 mL unit). The statistical analysis by using One way ANOVA shows a significant difference in blood glucose level among the five groups of treatment with p-value = 0,000. Post Hoc Test shows that the first, second, and third group have the same effectively as the positive control group to decrease the blood glucose level with p > 0,05.

scholarly journals The antipyretic effect of bitter melon (Momordica charantia) leaf in male white mice

2011 ◽  
Vol 9 (1) ◽  
pp. 7-11
Author(s):  
ELLY FAUZIAH ERMAWATI ◽  
SAMIGUN SAMIGUN ◽  
ENDANG SRI HADJANTI
Keyword(s):  
Body Weight ◽  
Negative Control Group ◽  
Positive Control ◽  
Statistical Test ◽  
Negative Control ◽  
Momordica Charantia ◽  
Positive Control Group ◽  
Control Group ◽  
Bitter Melon ◽  
Antipyretic Effect

Ermawati EF, Samigun, Hadjanti ES. 2011. The antipyretic effect of bitter melon (Momordica charantia) leaf in male white mice. Biofarmasi 9: 7-11. The potential of antipyretic effect of flavonoid in bitter melon (Momordica charantia L.) leaf is one of the traditional medicines that people used. This research aimed to determine the antipyretic effect of the extract of bitter melon leaf in male white mice. This experimental research was arranged as a post-test only controlled group design. Thirty Wistar furrow white mice with 2 months of ages and 100 gram in body weight were used as an animal model. Those mice were grouped equally into five groups, consisted of negative control group (2 ml water), positive control group (6.3 mg paracetamol/100 g body weight of mice/2 ml water), the first dose of the extract of bitter melon leaf (0.756 mg/100 g body weight of mice/2 ml water), the second dose of extract (1.512 mg/100 g body weight mice/2 ml water) and the third dose of extract (2.268 mg/100 g body weight mice/2 ml water). The measurement of mice temperature was conducted before and 2 hours after treated by DPT vaccine, and every 30 minutes post-treatment until 180 minutes. The result of this research was analyzed by using Anova statistical test and post-hoc test. The result of Anova statistical test showed significant differences among groups of variance, but there was no significant difference among times of variance. The result of posthoc test showed the significant differences between negative control group, positive control group and the extract of bitter melon leaf group. This research concluded that there was an antipyretic effect in the extract of bitter melon leaf in male white mice, but the effect was lower than paracetamol effect.

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