scholarly journals PHYTOCHEMICAL SCREENING AND PHYSIOCHEMICAL STUDIES ON AERIAL PART OF ACHILLEA MILLEFOLIUM LINN. FOUND IN KASHMIR

2021 ◽  
Vol 14 (2) ◽  
Author(s):  
Suheena Khanday ◽  
Afsahul Kalam ◽  
Ansar Ahmad Ansari ◽  
Aamir Yousuf ◽  
Sajad Salim ◽  
...  
Keyword(s):  
Physicochemical Parameters ◽  
Aerial Part ◽  
Perennial Herb ◽  
Achillea Millefolium ◽  
Western Himalayas ◽  
Phytochemical Screening ◽  
Good Source ◽  
Western Asia ◽  
Phytochemical Studies ◽  
Asteraceae Family

This studyis aimed to evaluate the physicochemical, macroscopic, microscopic and preliminary phytochemical studies of the aerial part of Achillea millefolium L., belonging to the Asteraceae family. It is a perennial herb and is distributed throughout the worldandis native to western Asia and Europe but is also found abundantly in most temperate regions including North America (Anne et al., 2006). Western Himalayas from Kashmir to Kumaon (6000-9000 feet above sea level), also serve as a good source for its production. The plant possesses many important phyto-chemicalslike sesquiterpenes, phenolic compounds, essential oils, etc. The plant has anti-inflammatory, antioxidant, antifungal, antitumor, antiseptic, spasmolytic and hemostatic properties. As there is no detailed standardization work reported on aerial part of Achillea millefolium L., the objective of this study was to work out the physicochemical parameters, macroscopic and microscopic study and preliminary phytochemical constants. The study revealed specific identities for the crude drug which will be useful in identification and to check the adulteration of the raw drug.

scholarly journals THE CHEMICAL COMPOSITION OF THE FRACTIONS OF THE AERIAL PART OF CULTIVATED CHICORY AND THEIR ANTIOXIDANT ACTIVITY

2021 ◽  
pp. 165-173
Author(s):  
Ol'ga Leonidovna Saybel ◽  
Andrey Ivanovich Radimich ◽  
Grigoriy Vasil'yevich Adamov ◽  
Tamara Darizhapovna Dargaeva ◽  
Nikolay Borisovich Fadeev ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Aerial Part ◽  
Raw Materials ◽  
Antioxidant Properties ◽  
Ethyl Acetate Fraction ◽  
Biologically Active ◽  
Perennial Herb ◽  
Cultivated Plants ◽  
The Russian Federation ◽  
Asteraceae Family

Chicory (Cichorium intybus L.) is a biennial or perennial herb of the Asteraceae family, growing in the Russian Federation under natural conditions in meadows, forest glades, grassy slopes, as well as on wastelands, fields, overgrown dumps and roadsides. Along with the wild-growing chicory, breeding varieties of cultivated plants are also known, intended for obtaining roots, while the aboveground part, which is a root rosette of leaves, is a production waste. The purpose of this study was to study the qualitative composition and antioxidant properties of biologically active substances (BAS) of the aerial part of cultivated chicory and to assess the potential for using secondary raw materials of this plant in the pharmaceutical industry for obtaining medicines. As a result of the study by HPLC-UV-MS / MS, it was found that the phenolic complex of the aerial part of the cultivated chicory is represented by phenol carboxylic acids - esters of caffeic, ferulic, coumaric acids with organic acids (quinic and tartaric) in various combinations; trace amounts of oxycoumarins (chicoriin); flavonoids (glycosides of quercetin, luteolin and isorhamnetin). The study of the antioxidant properties of BAS fractions of different polarity showed that the ethyl acetate fraction has the highest activity. It was found that the main dominant compound of this fraction is cichoric acid, which suggests that it is this metabolite that makes a decisive contribution to the antioxidant activity of the fraction and the extract as a whole.

Standardization and Phytochemical screening of Carica papaya seeds

2021 ◽  
pp. 4540-4546
Author(s):  
Varsha Singh ◽  
Aleza Rizvi ◽  
Udaivir Singh Sara
Keyword(s):  
Physicochemical Parameters ◽  
Plant Secondary Metabolites ◽  
Chemical Properties ◽  
Fluorescence Analysis ◽  
Water Soluble ◽  
Correct Identification ◽  
Phytochemical Screening ◽  
Physico Chemical ◽  
Hexane Extracts ◽  
Phytochemical Studies

The present work focus to evaluate the physicochemical and preliminary phytochemical studies on the seeds of family Caricaceae. The plants resources which are used in pharmaceutical formulation standardization was carried out on the basis of organoleptic properties, physical characteristics, and physico-chemical properties. Different Physicochemical parameters ash values, extractive values, loss on drying, foreign matter, fluorescence analysis, and pH were evaluated. Macroscopical characteristics and Physicochemical parameters like total ash, acid insoluble ash and water soluble ash were found to be 83.7%, 71.7% and 61.5% w/w respectively. Hexane, ethyl acetate, ethanol and water soluble extractive values (hot)were 7.6%, 11.6%, 27.4%, 37.5%w/w respectively. The pH of 1% and 10% aqueous solution was found to be 3.57 and 3.78 respectively. Preliminary phytochemical screening showed the presence of Tannins, Proteins and amino acids, Glycosides, Phenolic compounds, Carbohydrates, Saponins, Alkaloids and Flavonoids. Thin layer chromatographic studies also had been done on ethanolic and hexane extracts. HPTLC fingerprinting is a valuable method for the quantitative determination of phytochemicals present in plant extract. These studies aim to investigating referential information for correct identification and standardization of this plant secondary metabolites.

Antihyperglycemic, Antihyperlipidemic and Antioxidant Effects of Cotula cinerea (Del) in Normal and Streptozotocin-Induced Diabetic Rats

2020 ◽  
Vol 20 (9) ◽  
pp. 1504-1513 ◽  
Author(s):  
Ayoub Amssayef ◽  
Mohamed Eddouks
Keyword(s):  
Antioxidant Activity ◽  
Glucose Tolerance ◽  
Oral Administration ◽  
Beneficial Effect ◽  
Aqueous Extract ◽  
Aerial Part ◽  
Diabetic Rats ◽  
Histopathological Analysis ◽  
Phytochemical Screening ◽  
Cotula Cinerea

Aims: The current investigation aimed to assess the antioxidant, antidiabetic and antilipidemic effects of the aqueous extract of aerial part of Cotula cinerea (C. cinerea). Background: Cotula cinerea (Del). which belongs to the Asteraceae family is commonly used traditionally for the treatment of diabetes. Objective: The objective of the study was to study the effect of the aqueous C. cinerea extract on glucose and lipid metabolism in normal and streptozotocin-induced diabetic rats using a single and repeated oral administration. Methods: A preliminary phytochemical screening and the quantification of phenolic and flavonoid contents as well as the antioxidant activity using three methods (DPPH, FRAP and ABTS) were carried out. The effect of a single and repeated (15 days of treatment) oral administration of the aqueous extract of aerial part of Cotula cinerea (AEAPCC) at a dose of 20 mg/kg on glucose and lipid profile was examined in normal and streptozotocin-induced diabetic rats. Additionally, histopathological examination of the pancreas and liver was carried out according to the Hematoxylin-Eosin method. Results: AEAPCC (20 mg/kg) showed a significant blood glucose-lowering activity in both normal and diabetic rats after a single and repeated oral administration during 15 days. The aqueous extract was also able to decrease the plasma triglycerides levels in both normal and diabetic rats after 15 days of oral treatment at a dose of 20 mg/Kg while no effect was observed on plasma cholesterol levels. In addition, the results show that AEAPCC exhibits an in vitro antioxidant activity using different tests. Histopathological analysis of the pancreas and liver of AEAPCC-treated diabetic rats has revealed that AEAPCC had a beneficial effect on the architecture of these organs while no improvement of glucose tolerance was noticed using the glucose tolerance test. Furthermore, the results showed that the extract is rich in several phytochemical compounds and exhibited an important antioxidant activity. The phytochemical screening revealed that AEAPCC contains polyphenolic compounds, flavonoids, tannins, alkaloids, saponins, quinones, sterols, terpenoids, anthroquinones and reducing sugars. Whereas, it is free from glycosides. Conclusion: In conclusion, this study demonstrates that Cotula cinerea possesses a beneficial effect on diabetes. Further investigations are required to study the mechanism of action of the antidiabetic effect of this plant.

PHENOLIC COMPOUNDS AND ANTIOXIDANT ACTIVITY GLYCYRRHIZA PALLIDIFLORA HERB (GLYCYRRHIZA PALLIDIFLORA MAXIM.)

2021 ◽  
pp. 42-46
Author(s):  
Maltseva E.M. ◽  
Egorova I.N. ◽  
Pinchuk L.G.
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Compounds ◽  
Russian Far East ◽  
Far East ◽  
Biologically Active ◽  
Perennial Herb ◽  
Total Phenolic ◽  
Plant Antioxidants ◽  
Phytochemical Studies ◽  
First Time

Pale-flowered licorice (Glycyrrhiza pallidiflora Maxim.) is the pea family (Fabaceae) perennial herb. It is a Russian Far East endemic. Pale-flowered licorice refers to the false (not sweet) licorice section (Pseudoglycyrrhiza Krug.), which do not accumulate glycyrrhizin derivatives. The G. pallidiflora successful introduction has been carried out over the past 5 years in the “Apothecary garden” territory, FRC UUH SB RAS, Kemerovo. Phytochemical studies screening biologically active compounds main classes of the plant aerial part confirmed the presence of a complex of phenolic compounds. The content of catechin derivatives and condensed-type tannins - proanthocyanidins (PAC) data in G. pallidiflora herb were obtained for the first time. In different years of cultivation, licorice herb accumulates phenolic compounds - up to 2.83 ± 0.22% in terms of gallic acid, flavonoids - up to 2.44 ± 0.03% in terms of rutin and PAC in terms of cyanidine chloride - up to 2.61 ± 0.11%. It was found that the maximum content of the phenolic compounds and PAC sum was observed in the herb for 4 years development. The greatest number of flavonoids accumulates in the herb harvested in the 3rd year of cultivation. A positive significant linear relation was found between antioxidant activity (AOA) and the total phenolic compounds and PAC content (r≥0.98). Considering that BAC with IC values ≤ 50 μg / ml in the DPPH assay refer to active antioxidant’s licorice herb can be classified as a plant with high antioxidant potential. It was found that the iron chelating activity of the G. pallidiflora herb is in direct dependence (r≥0.94) on the content of flavonoids. The obtained results demonstrate the importance of further study of this plant as a source of BAC, including plant antioxidants.

scholarly journals Pharmacognostical Studies on Leaves of Madhuca longifolia (koen) Macbr

2021 ◽  
Vol 71 (1) ◽  
Author(s):  
Sumaira Nasreen Mohammed Tahir
Keyword(s):  
Wound Healing ◽  
Indigenous People ◽  
Physicochemical Parameters ◽  
Chemical Constituents ◽  
Initial Step ◽  
Madhuca Longifolia ◽  
The Status ◽  
Phytochemical Studies ◽  
Wound Healing Activity

Madhuca longifolia (koen) macbr is an ever-green tree belonging to family sapotaceae commonly known as mahua. The leaf is used by the indigenous people of Australia in curing bleeding, gums, expectorant, cushing`s disease, wound healing activity and various ailments. The present study comprises macroscopy, microscopy, histochemistry, physicochemical parameters, phytochemical studies and florescence analysis. Pharmacognosy is the initial step for determining the status of organ of plant considered as a crude medicine; hence the current study was done, TLC of flavonoid as a chemical constituents present in the drug for establishing the biomarker compound. These studies will help in future for establishing the pharmacopoeial drug standards.

PRELIMINARY PHARMACOGNOSTIC AND PHYTOCHEMICAL STUDIES ON AERIAL ROOTS OF FICUS BENGHALENSIS LINN.

INDIAN DRUGS ◽  
2015 ◽  
Vol 52 (11) ◽  
pp. 14-18
Author(s):  
S. J. Jain ◽  
◽  
T. A. Khan
Keyword(s):  
Ethyl Acetate ◽  
Phenolic Content ◽  
Total Phenolic ◽  
Phytochemical Screening ◽  
Calcium Oxalate Crystals ◽  
Ficus Benghalensis ◽  
Aerial Roots ◽  
Powder Characteristics ◽  
Growth Promoting ◽  
Phytochemical Studies

The aerial roots of Ficus benghalensis Linn (Moraceae) have been reported to have immunomodulatory, anti-bacterial and hair growth promoting activities. There are no reports on pharmacognostical and phytochemical investigations of these aerial roots. The aim of the present study was evaluation of sectional microscopy, powder characteristics, preliminary phytochemical screening of successive solvent extracts (petroleum ether, toluene, dichloromethane, methanol, ethyl acetate and aqueous extracts) of the aerial roots. The result of the sectional microscopy indicated the presence of cork cells, phloem and xylem. The powder characteristics indicated the presence of calcium oxalate crystals, lignified fibers. Preliminary phytochemical screening indicated the presence of flavonoids, phenolics and saponins. An extract rich in flavonoids (ethyl acetate rich extract) of the aerial roots was prepared and a quantitative analysis of total flavonoid and total phenolic content was done.

scholarly journals PHYTOCHEMICAL SCREENING AND EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF AERIAL PART EXTRACTS OF PLANTAGO MAJOR L.

2017 ◽  
Vol 10 (9) ◽  
pp. 307
Author(s):  
Jyoti Vandana ◽  
Gupta A K ◽  
Alok Mukerjee
Keyword(s):  
Aerial Part ◽  
Iridoid Glycosides ◽  
Inflammatory Activity ◽  
Albino Rats ◽  
Plantago Major ◽  
Phytochemical Screening ◽  
Paw Edema ◽  
Edema Model ◽  
Anti Inflammatory ◽  
Wistar Albino Rats

  Objective: This study aims to perform phytochemical screening and investigate anti-inflammatory activity of extract from aerial part of the plant Plantago major L.Methods: Preliminary phytochemical screening of plant extract was carried out using standard qualitative procedures and anti-inflammatory activity was evaluated using carrageenan-induced paw edema model in male Wistar albino rats using plethysmometer. Diclofenac sodium (10 mg/kg, b.w.) was used as standard drug.Results: Preliminary phytochemical screening of the different extracts revealed that they were rich in secondary metabolite compounds such as carbohydrates, tannins, steroids, flavonoids, terpenoids, glycosides, fats and oils, alkaloids, phenolic compounds, and iridoid glycosides. The anti-inflammatory activity was evaluated using carrageenan-induced paw edema models in Wistar albino rats. The anti-inflammatory activity of methanolic extract (ME) was found to be dose dependent in carrageenan-induced paw edema model. The ME has shown significant (p<0.05) inhibition of paw edema, 61.11% and 55.55% on 4th hr at the doses of 900 and 600 mg/kg, respectively.Conclusion: The results of the present study demonstrate that ME of the aerial parts of the plant possess significant (p<0.05) anti-inflammatory potential.

scholarly journals Phytoaccumulation of metals in three plants species of the Asteraceae family sampled along a highway

2021 ◽  
Vol 49 (2) ◽  
pp. 12180
Author(s):  
Radmila M. GLIŠIĆ ◽  
Zoran B. SIMIĆ ◽  
Filip J. GRBOVIĆ ◽  
Vera R. RAJIČIĆ ◽  
Snežana R. BRANKOVIĆ
Keyword(s):  
Plant Species ◽  
Road Traffic ◽  
Living Organism ◽  
Achillea Millefolium ◽  
Hyperaccumulator Plants ◽  
Stems And Leaves ◽  
The City ◽  
Asteraceae Family ◽  
Surrounding Soil

The aim of this study was to determine the ability of roots and above-ground parts of three plant species of the Asteraceae family (Matricaria inodora L., Achillea millefolium L., Crepis setosa Haller fill.) for bioaccumulation and translocation of eight metals (Ca, Mg, Fe, Mn, Cu, Zn, Pb, Cr). Those plants were sampled directly along the lanes of the highway at the entrance into the City of Kragujevac, Republic of Serbia. The investigated metals are emitted into the air from road traffic and are deposited in the surrounding soil. Many of them are toxic to the living organism, and it is, therefore, necessary to apply effective, economical, sustainable methods for their removal from the environment. An example of such a method is as phytoremediation, based on the use of metal hyperaccumulator plants. The results of this research showed the species studied differ in the absorption, translocation and accumulation of investigated metals. They also showed that species M. inodora and A. millefolium (leaves) can be used for the phytoextraction of Ca, Mg, Fe, Mn, Cu, Zn and Cr, species C. setosa (leaves) for Ca, Mg and Cu species M. inodora (stem) for Cr. The results further indicate that all three species absorb Zn from the soil and translocate it to the stems and leaves. All three of the studied species are suitable for phytostabilization of soils loaded with Zn, but only the species M. inodora and C. setosa can be applied in phytoremediation of this metal. 

scholarly journals Biochemical composition, nutritional analysis and antioxidant activity of Buchanania lanzan Spreng fruits

2021 ◽  
pp. 180-187
Author(s):  
Madhuri Suryawanshi ◽  
Vilas Patil ◽  
Varsha Jadhav (Rathod)
Keyword(s):  
Methanol Extract ◽  
Antioxidant Property ◽  
Unripe Fruit ◽  
Good Source ◽  
Total Polyphenol ◽  
Nutritional Analysis ◽  
The Family ◽  
Primary Focus ◽  
Phytochemical Studies ◽  
Unripe Fruits

Buchanania lanzan Spreng belongs to the family Anacardiaceae. The primary focus of this study was to examine phytochemical, proximate, antioxidant property and GCMS evaluation of unripe and ripen fruit of B. lanzan Spreng. The phytochemical studies showed that alkaloids, phenols, flavones, saponins, coumarins, glycosides and tannins are present in both ripen and unripe fruits. The proximate evaluation confirmed that crude fat (14.5%) and protein (6.37±0.69 g/100g) is high in ripen fruit. In unripe fruit (11.3%) crude fat and protein (4.11%) is less percent. The carotenoid (5.58 ± 0.5 mg/100g) and catalase (0.226±0.074 mg/100g) activity is higher in unripe fruit. The total polyphenol (6.4±0.8 mg/100g) and peroxidase (0.362±0.017 mg/100g) content show greater activity in ripen fruit. In DPPH and FRAP highest activity showed in methanol extract of ripen and unripe fruit than the other solvent. GC-MS evaluation showed many bioactive compounds present in unripe and ripen fruit. It is concluded that nutritional and bioactive ability is high in ripen and unripe fruits of B. lanzan. The fruits of B.lanzan are a good source of nutrition and medicinally important.

scholarly journals PRELIMINARY COMPARATIVE PHARMACOGNOSTIC STUDY OF GENUINE AND ADULTERANT RAW MATERIAL IN ATIVISHA (ACONITUMHETEROPHYLLUM WALL. EX ROYLE)

2021 ◽  
Vol 10 (3) ◽  
pp. 3051-3054
Author(s):  
P Khobragade
Keyword(s):  
Quality Assurance ◽  
Sweet Taste ◽  
Tuberous Root ◽  
The Other ◽  
Raw Material ◽  
Perennial Herb ◽  
Western Himalayas ◽  
Starch Grains ◽  
Market Sample ◽  
Aconitum Heterophyllum

Ativisha consists of the dried tuberous root of the aconitum heterophyllum wall. ex royle of ranunculaceae family. a perennial herb native and endemic to western himalayas. it is popular drug that is extensively used in ayurvedic pediatric medicine, specially used in respiratory disorders, fever, diarrhoea and vomiting in children. the fact that the suppliers of crude herbal materials are mostly traders having limited knowledge of their true identity. due to unavailability and high cost, they use their substitutes and adulterants in order to get more and more benefits. children's being more vulnerable, special care has to be taken in selecting the drugs. this paper includes preliminary pharmacognostical but very important aspects to ensure the standard and quality assurance of the raw drug of ativisha. preliminary comparative pharmacognostic study of genuine and adulterant raw material in ativisha. here the sample genuine ativisha with both small and big sized starch grains and taste is bitter followed by salivation in the mouth it may official ativisha. where the other sample with big starch grains with sweet taste may be an adulterated market sample sold under the name of ativisha.

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