scholarly journals Contribution of Nanotechnology and Nanomaterials to the Treatment of Diabetic Patients by Aid of Novel Inventions

2020 ◽  
pp. 29-40
Author(s):  
Shiva Najigivi ◽  
Seyedahmadreza Mirmotallebi ◽  
Alireza Najigivi
Keyword(s):  
Diabetes Mellitus ◽  
Drug Delivery ◽  
Human Health ◽  
Carbon Nanostructures ◽  
Closed Loop ◽  
Insulin Injection ◽  
Diabetic Patients ◽  
Temporal Response ◽  
Nanoscience And Nanotechnology ◽  
The Impact

Nanoscience and Nanotechnology are highly growing their significance in diabetic supplies and research nowadays. It is an area that included nanomaterials, nanosensors and nanostructures as well as nanoparticle projects and also their usage in human health research. Particularly, nanotechnology helps to the production of diabetic supplies, materials together with the development of novel glucose and insulin injection devices as well as their measurement sensors by the aid of nanomaterials. These materials mostly could be metal nanoparticles together with carbon nanostructures by nano dimension delivery mechanisms modalities which hold the potential to vividly recover the excellence of life of diabetic patients. Nanoscience and nanotechnology in diabetic research have facilitated and provided more truthful data for identifying diabetes mellitus. It is also worth mentioning that the nanotechnology could highly enhance the impact of drug delivery by addition of nanoscale materials and increase the glucose feeling, temporal response as well as glucose nursing. Furthermore, it is proposing novel nanoscale methods named closed-loop insulin delivery approaches which mechanically release insulin drug in reply to fluctuating blood glucose heights. Besides, the mixture of nanotechnology by medication has shaped a novel field of nanomedicine which could enhance human health level. It is worthwhile to mention that some of the applications of nanotechnology for the treatment of diabetic patients can be the production of diabetic supplies by nanotechnology. One of the most important diabetic instruments that could highly relieve the life of patients these days could be nano diabetic shoes which will describe here. In this research, applications of nanoscience and nanotechnology in treating diabetic patients were discussed.

Adjuvant Supplementation with L-Carnitine in Diabetic Population and its effects on Lipid Parameters

2021 ◽  
Vol 15 (8) ◽  
pp. 2017-2019
Author(s):  
Rao Salman Aziz ◽  
Usman Saeed ◽  
Nasim Aslam Ghumman ◽  
Muhammad Arshad ◽  
Asif Sohail ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Triglyceride Level ◽  
Clinical Care ◽  
Diabetic Patients ◽  
Healthy Population ◽  
Patients With Diabetes ◽  
Diabetic Population ◽  
Large Discount ◽  
The Impact ◽  
Lipid Parameters

Background: Diabetes is a complicated disease requires continuous clinical care, to govern blood sugar. Aim: To decides the impact of management of L carentin to diabetics at the lipid profile. Methods: This study turned into performed on 120 diabetic Patients had been decided on from endocrinology and diabetes, inside decided on standards. The Patients distributed into three Strata (1st Strata of healthy population and two Strata of patients with diabetes who were on metformin and glibenclamide, one Strata took a L carnitine in a dose of 1000 mg TDS and a Strata dealing with a placebo for a period of ninety days). Results: It is observed those who are on Lcarnitine, confirmed a large discount (p <0.05) with inside the triglyceride level, at the same time as no large adjustments had been located withinside the level of cholesterol and HDL and LDL. Conclusion: These study outcomes that management of L carentin improved profile of lipid in type-2diabetic Patients. Keyword: Dyslipidemia, Diabetes mellitus (DM), l-carnitine (LC).

scholarly journals Examining and investigating the impact of demographic characteristics and chronic diseases on mortality of COVID-19: Retrospective study

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257131
Author(s):  
Abbas Al Mutair ◽  
Alya Al Mutairi ◽  
Saad Alhumaid ◽  
Syed Maaz Abdullah ◽  
Abdul Rehman Zia Zaidi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Saudi Arabia ◽  
Binary Logistic Regression ◽  
Demographic Characteristics ◽  
Control Measures ◽  
Effective Control ◽  
Diabetic Patients ◽  
History Of ◽  
And Gender ◽  
The Impact

Background Epidemiological features characterization of COVID-19 is highly important for developing and implementing effective control measures. In Saudi Arabia mortality rate varies between 0.6% to 1.26%. The purpose of the study was to investigate whether demographic characteristics (age and gender) and non-communicable diseases (Hypertension and Diabetes mellitus) have a significant association with mortality in COVID-19 patients. Methods Prior to data collection, an expedite approval was obtained from Institutional Review Board (IRB Log No: RC. RC20.09.10) in Al Habib Research Center at Dr. Sulaiman Al-Habib Medical Group, Riyadh, Saudi Arabia. This is a retrospective design where we used descriptive and inferential analysis to analyse the data. Binary logistic regression was done to study the association between comorbidities and mortality of COVID-19. Results 43 (86%) of the male patients were non-survivors while 7 (14%) of the female patients were survivors. The odds of non-survivors among hypertensive patients are 3.56 times higher than those who are not having a history of Hypertension (HTN). The odds of non-survivors among diabetic patients are 5.17 times higher than those who are not having a history of Diabetes mellitus (DM). The odds of non-survivors are 2.77 times higher among those who have a history of HTN and DM as compared to those who did not have a history of HTN and DM. Conclusions Those patients that had a history of Hypertension and Diabetes had a higher probability of non-survival in contrast to those who did not have a history of Diabetes and hypertension. Further studies are required to study the association of comorbidities with COVID-19 and mortality.

scholarly journals Impact of diabetes mellitus on bladder uroepithelial cells

2013 ◽  
Vol 304 (2) ◽  
pp. R84-R93 ◽  
Author(s):  
Ann T. Hanna-Mitchell ◽  
Giovanni W. Ruiz ◽  
Firouz Daneshgari ◽  
Guiming Liu ◽  
Gerard Apodaca ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Barrier Function ◽  
Transient Receptor Potential ◽  
Quantitative Polymerase Chain Reaction ◽  
Diabetic Patients ◽  
Transient Receptor Potential Vanilloid ◽  
Sprague Dawley ◽  
Bladder Smooth Muscle ◽  
Chronic Hyperglycemia ◽  
The Impact

Diabetic bladder dysfunction (DBD), a prevalent complication of diabetes mellitus (DM), is characterized by a broad spectrum of symptoms including urinary urgency, frequency, and incontinence. As DBD is commonly diagnosed late, it is important to understand the chronic impact of DM on bladder tissues. While changes in bladder smooth muscle and innervation have been reported in diabetic patients, the impact of DM on the specialized epithelial lining of the urinary bladder, the urothelium (UT), is largely unknown. Quantitative polymerase chain reaction analysis and electron microscopy were used to evaluate UT gene expression and cell morphology 3, 9, and 20 wk following streptozotocin (STZ) induction of DM in female Sprague-Dawley rats compared with age-matched control tissue. Desquamation of superficial (umbrella) cells was noted at 9 wk DM, indicating a possible breach in barrier function. One causative factor may be metabolic burden due to chronic hyperglycemia, suggested by upregulation of the polyol pathway and glucose transport genes in DM UT. While superficial UT repopulation occurred by 20 wk DM, the phenotype was different, with significant upregulation of receptors associated with UT mechanosensation (transient receptor potential vanilloid subfamily member 1; TRPV1) and UT autocrine/paracrine signaling (acetylcholine receptors AChR-M2 and -M3, purinergic receptors P2X2 and P2X3). Compromised barrier function and alterations in UT mechanosensitivity and cell signaling could contribute to bladder instability, hyperactivity, and altered bladder sensation by modulating activity of afferent nerve endings, which appose the urothelium. Our results show that DM impacts urothelial homeostasis and may contribute to the underlying mechanisms of DBD.

A Descriptive Study to Assess the Knowledge and Attitude regarding Self Administration of Insulin Injection among Diabetes Mellitus patient in selected Hospital of Visnagar City, in view of Information Booklet

2021 ◽  
pp. 499-502
Author(s):  
Himani Patel ◽  
Daxaben P. Patel
Keyword(s):  
Diabetes Mellitus ◽  
Standard Deviation ◽  
Family History ◽  
Insulin Injection ◽  
Attitude Scale ◽  
Diabetic Patients ◽  
Structure Questionnaire ◽  
Self Administration ◽  
Level Of Knowledge ◽  
Knowledge And Attitude

Introduction: Diabetes Mellitus is an endocrine disorder, characterized by hyperglycemia that is, high blood sugar levels. This is caused due to a relative or absolute insulin deficiency, a hormone produced by the pancreas. Lack of insulin, either relative or absolute affects metabolism or breaking down of carbohydrates, proteins, fat, water and electrolytes leading to an accumulation of glucose in the blood. Till the earlier part of this century, it was believed that there was no effective treatment for this condition, until the discovery of insulin, in 1922, by Fredrick Banting and his student, John McCleod1 Design: A descriptive survey approach was used for assessing the knowledge and attitude of Diabetes Mellitus patients regarding Self-Administration of insulin injection. Participants: The target population consisted of 60 Diabetic patients who were on Insulin Therapy within the age group of 40-70 years. Half of the patients were admitted and a few were attending the OPD services in Nootan General Hospital at visnagar. Interventions: Booklet information was given to the patients. Tool: Structure questionnaire was used to assess the level of Knowledge regarding Self-Administration of insulin injection and used Likert’s attitude scale to assess attitude regarding Self-Administration of insulin injection among diabetes mellitus patients. Results: In this study. The total 60 sample under the study were 38.3% sample 61-70 years, 20% sample 51-60 years, 20% sample 41-50 years 8.3% sample below 40 years of age. Distributed sample according to gender were 73.3% are male and 26.7% are female. Distribution of sample based on education is 1.7% graduated 3.3% had higher secondary, 21.7% completed secondary and 73.3% sample had completed primary education as regards 53.3% samples were unemployed 23% self-employed. According to family history 36.7% had family history of DM 63.3% had no family history. The level of knowledge regarding self-administration of the insulin injection were 81.7% had average knowledge, 13.3% had poor knowledge and only 5% had good knowledge regarding self-administration of insulin injection. The overall mean value of the diabetic patients knowledge regarding self-administration of insulin injection was 14.45 with a standard deviation of 3.326. This finding showed that the most of the diabetic patients were not much aware of self-administration of insulin injection. The level of attitude regarding self-administration of insulin injection was assessed were, only 18.3% had most favorable and 81.7% had a favorable attitude towards self- administration of insulin injection. It revealed the mean percentage of the positive attitude, which was 69.05 with a standard deviation of 5.585. These results showed that most of the diabetic patients were not having a most favourable attitude towards self-administration of insulin injection. Conclusion: The finding indicates that the Booklet information was a suitable and effective method of instruction for updating and enhancing the knowledge and attitude among patients.

scholarly journals The Impact of COVID-19 on Diabetes Mellitus and Hypertension: A Retrospective Study

2021 ◽  
pp. 68-77
Author(s):  
S. Pavithra ◽  
S. Lavanya ◽  
P. Vaishnavi ◽  
A. Rakesh Rosario ◽  
Priyadharshini A ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Retrospective Study ◽  
Diabetic Patients ◽  
Hypertensive Patients ◽  
Study Population ◽  
The Impact

COVID-19 is a pathogenic virus that caused a pandemic outbreak in December 2019. The impact of this virus may be severe in the patients having co-morbidities like diabetes, hypertension, Chronic Kidney Disease, cardiovascular disease, etc. Aim and Objectives: This study Aims in Assessing the impact of COVID-19 on Diabetic and Hypertensive patients as well as COVID-19 patients without any co-morbidities. Objective of this is to evaluate the association between COVID-19 and its risk factors (diabetes and hypertension) and to evaluate whether the severity of the symptoms in COVID-19 patients is due to comorbidities or past medications. Methodology: A Retrospective study was conducted in SRM Hospital (Medical Records Department) for a period of 3 Months with the study population 670 at the age group of 25, known case of Diabetes and Hypertension. Cases of Pregnant women are excluded from the study. The patients were grouped into 4 categories 1) control group (patient without any co-morbidities) 2) diabetic patients 3) Hypertensive patient 4) Diabetic+Hypertension patient and studied their prescribing pattern by collecting the past medication history. Results and Discussion: There is a significant decrease in a lymphocyte in covid-19 Type 2 diabetic patients in our study. These results suggest that different mechanism exists for hypertension and diabetes mellitus as risk factors for covid-19. It is also known that these patients have impaired immune response to many infections [30]. In our retrospective study, we collected 670 covid-19 cases. It consists of 12.5% of diabetic patients and 6.6% of hypertensive patients. This study compared COVID-19 patients without any comorbidity (neither Type 2 diabetes mellitus nor hypertension) with covid- 19 patients with comorbidities (Type 2 diabetes mellitus and hypertension). COVID-19 patients with T2DM have an increased level of D-dimer compared to non-T2DM patients. Conclusion: Diabetic and hypertensive patients affected with COVID-19 are low in our study. Out of the total study population, only 12.5% are diabetic, 6.56% are hypertensive, and 9.25% were both diabetic and hypertensive. But when comparing in terms of severity, hypertensive and diabetic patients have severe effects than the control patients. In simpler terms, not every person who has diabetes and hypertension are affected with COVID-19, but those who were affected by COVID-19 showed more severity than the patients who don't have any comorbidities

scholarly journals 711 Effect of Roux-En-Y Gastric Bypass on HbA1c As Well As Number of Medications in Diabetic Patients

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
M Bhandari ◽  
M Rao ◽  
G Bussa ◽  
C Rao
Keyword(s):  
Diabetes Mellitus ◽  
Gastric Bypass ◽  
Glycosylated Haemoglobin ◽  
Morbidly Obese ◽  
Diabetic Patients ◽  
Obese Patients ◽  
The Mean ◽  
The Impact

Abstract Aim Roux en Y gastric bypass (RYGB) is known to ameliorate Type 2 Diabetes Mellitus (T2DM) in morbidly obese patients. We aimed to determine both the reduction in the glycosylated haemoglobin (HbA1c) and the number of anti-diabetic medications (including insulin) in diabetic patients undergoing RYGB over a five-year period. Method We reviewed data of diabetic patients (n = 530) who underwent RYGB from January 2012 – December 2017, including those with a minimum of a 2-year post-operative follow up (n = 47). Preoperatively, BMI, HbA1c and the number of anti-diabetic medications and the duration of T2DM since diagnosis were recorded. These measurements were repeated at the end of the two year follow up. Results At the time of enrolment in the bariatric programme, the median BMI was 42.5 (range, 31.7-61.5) kg/m2, mean duration of T2DM was 58 months and median HbA1c was 59 (37-118) mmol/mol. The mean number of anti-diabetic medications taken, including insulin, was 2. At the end of 2-year follow-up, the median BMI was 32 (range, 24-41) kg/m2 and HbA1c was 41(range, 33-91) mmol/mol. 15 patients (31.9%) still required anti-diabetic medication, 12 of whom had a diagnosis of T2DM for 3 years or more at time of enrolment. Conclusions RYGB is strongly associated with a resolution of T2DM in morbidly obese patients. In those who were not resolved, the number of anti-diabetic medications taken and HbA1c were reduced. The impact of the surgery is dependent on the duration of T2DM since diagnosis preoperatively.

scholarly journals The impact of diabetes mellitus on the anti-tuberculous treatment outcome: a series of cases from the Republic of Moldova

2021 ◽  
Vol 94 (3) ◽  
pp. 325-332
Author(s):  
Evelina Lesnic ◽  
Alina Malic ◽  
Ovidiu Tafuni
Keyword(s):  
Diabetes Mellitus ◽  
Treatment Outcome ◽  
Statistical Analysis ◽  
Treatment Effectiveness ◽  
Tuberculosis Treatment ◽  
Control Group ◽  
Diabetic Patients ◽  
Republic Of Moldova ◽  
The Republic ◽  
The Impact

Background and aims. The Republic of Moldova ranks among the European Region countries with the highest global incidence of tuberculosis. Almost 5% of the cases with pulmonary TB had been diagnosed with DM in 2017. The aim of this study was to assess the impact of diabetes mellitus on the anti-tuberculosis treatment effectiveness for the improvement of the disease outcome. Methods. A retrospective, longitudinal and case-control study, which included a total number of 252 patients diagnosed with pulmonary tuberculosis and distributed into a study group of 93 patients diagnosed with diabetes mellitus and a control group of 159 patients without glycemic disorders was performed. The statistical analysis was performed using EpiInfo software. The statistical analysis of the differences between normally distributed continuous variables was tested with the Student T-test. Results. Based on the collected data we established that the majority of the patients with glycemic disorders were diagnosed with the type 2 diabetes, associated with hyperglycemia and in half of them complications of diabetes were revealed. The age older 55 years and the low economical state were common characteristics of the diabetic patients. Tuberculosis was detected in every second diabetic patient through the radiological screening compared with the passive detection of most of the non-diabetic patients. The anti-tuberculosis treatment outcome was endangered by a higher rate of the adverse drug events in patients with diabetes, which contributed to death in 15%, lost to follow-up 7%, and therapeutic failure in 6%. Conclusions. The anti-tuberculous treatment outcome in patients diagnosed with tuberculosis and diabetes mellitus was significantly diminished by glycemic disorders, history of the previous anti-tuberculous treatment and adverse drug reactions. Individualized therapeutic approach to tuberculosis could improve the treatment effectiveness.

scholarly journals The effect of diabetes mellitus on evolution and outcome of tuberculosis in a prospective study

2021 ◽  
Vol 64 (5) ◽  
pp. 16-20
Author(s):  
Alina Malic ◽  
◽  
Evelina Lesnic ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Prospective Study ◽  
Treatment Effectiveness ◽  
Similar Rate ◽  
Control Group ◽  
Diabetic Patients ◽  
A Prospective Study ◽  
Prospective Longitudinal ◽  
The Impact

Background: In the Republic of Moldova almost 5% of the cases with tuberculosis are diagnosed annually among diabetic patients. The aim of this study was to assess the impact of diabetes mellitus on the evolution and anti-tuberculosis treatment effectiveness in a prospective study. Material and methods: A prospective, longitudinal and case-control study, which included a total number of 252 patients diagnosed with pulmonary tuberculosis and distributed in a study group, consisting of 93 patients diagnosed with diabetes mellitus and a control group, consisting of 159 patients without glycemic disorders, was performed. Results: This study identified that one half of the group with diabetes was detected by active screening and one third received anti-tuberculous treatment before actual episode. A similar rate of diabetic and non-diabetic patients was microbiologically positive, as well confirmed with drug-resistance. The anti-tuberculous treatment effectiveness was lower in diabetic patients, the death rate and the low treatment outcome (lost to follow-up and failed) were higher than in non-diabetic patients. The main causes of unfavorable evolution were: glycemic disorders (hyperglycemia), diabetes complications and the history of the anti-tuberculous treatment in the anamnesis. Conclusions: The individualized approach and a tight follow-up should be performed regularly in all patients with glycemic disorders and tuberculosis for the improvement of the disease outcome.

scholarly journals Metformin Therapy and Survival in Multiple Myeloma Among US Veterans with Diabetes Mellitus

Blood ◽  
2015 ◽  
Vol 126 (23) ◽  
pp. 4502-4502
Author(s):  
Jesse Keller ◽  
Kristen M. Sanfilippo ◽  
Suhong Luo ◽  
Brian F. Gage ◽  
Kenneth R Carson
Keyword(s):  
Diabetes Mellitus ◽  
Multiple Myeloma ◽  
Secondary Analysis ◽  
Growth Factor Receptor ◽  
Diabetic Patients ◽  
Defined Daily Dose ◽  
Metformin Therapy ◽  
Immortal Time Bias ◽  
The Impact

Abstract Background: Metformin is an oral biguanide anti-diabetic medication used in patients with type 2 diabetes mellitus (DM). Recently, metformin use in diabetic patients with multiple myeloma (MM) has been associated with improved overall survival (OS) (Wu et al, 2014). Additionally, long-term metformin use has been associated with a decrease in the rate of progression of MGUS to MM (Chang et al. 2015). These anti-tumor effects are hypothesized to be mediated through insulin receptor/insulin-like growth factor receptor-1 signaling and moderation of cellular effects of hyperglycemia and hyperinsulinemia. To confirm the association between metformin use and improved survival in diabetic patients with MM, we evaluated a cohort of United States veterans with MM and diabetes. Methods: Patients diagnosed with MM in the Veterans Administration database from September 1, 1999 to December 31, 2009 were identified and followed through October 2014. Patients who did not receive MM directed therapy within 6 months of diagnosis were excluded, as were patients who died within 1 year of MM diagnosis. Furthermore, patients who did not have a pre-existing diagnosis of DM at the time of MM diagnosis were excluded. To standardize dose-response effects, a defined daily dose (DDD) calculation of 1 gram of metformin daily was used. Cox modeling was used to assess the association between mortality and metformin use. Additional variables considered included: age, body mass index, race, use of novel therapeutic agents, transplantation, year of diagnosis, creatinine ≥ 1.5, albumin ≤ 3 g/dL and bisphosphonate use. Metformin use was evaluated as a time varying covariate to control for immortal time bias. Patients were defined as metformin users if they were prescribed metformin during a period starting 3 months prior to MM diagnosis extending through completion of follow-up. To assess for the impact of steroid-induced DM (SID), a secondary analysis including these patients was completed. Results: A total of 3,069 MM patients were evaluable, of whom 549 had a diagnosis of DM prior to MM diagnosis. Among these patients, 268 patients (49%) had received metformin therapy. Diabetic metformin users were younger (mean 66.5 years vs 68 years, P=0.0044), and had fewer comorbidities including chronic kidney disease (9.7% vs 37.4%, P < 0.0001) and ischemic heart disease (39.2% vs 48.8%, P < 0.0001), compared with diabetic non-metformin users . Additionally, metformin users were more likely to have undergone autologous stem cell transplantation (18.3% versus 8.2%, P=0.0005). There was no difference in mortality for metformin users versus non-users (adjusted HR (aHR) 1.11, 95% CI [0.88-1.39]). Utilization of DDDs to stratify metformin users by dose exposure showed no difference in mortality between those with ≥ 365 DDDs (aHR 0.96, 95% CI[0.71-1.29]) or those with < 365 DDDs (aHR 1.28, 95% CI[0.97 -1.70]), as compared to non-users. Among patients with DM or SID diagnosed at any time during follow-up, no significant association with survival was seen among users versus non-users, for any use of metformin (aHR 1.08, 95%CI[0.87 - 1.33]) or when stratified by ≥ 365 DDDs (aHR 0.96 95%CI[0.71-1.29]) or < 365 DDDs (aHR 1.28, 95%CI[0.97-1.70]). Conclusion: In contrast to a prior study reporting improvements in OS, we found no significant association between metformin use and OS in this cohort of diabetic patients with MM. This is largest cohort study performed to date to assess the role of metformin in patients with MM. This study does not support the prescription of metformin as adjunct therapy in MM. Disclosures Sanfilippo: Amgen: Speakers Bureau.

scholarly journals Knowledge and Self-Efficacy Towards Eating Behaviors by People Living with Diabetes Mellitus

2021 ◽  
pp. 288-298
Author(s):  
Lisa Anita Sari ◽  
Ani Astuti ◽  
Diah Merdekawati
Keyword(s):  
Diabetes Mellitus ◽  
Eating Behavior ◽  
Healthy Eating ◽  
Self Efficacy ◽  
Eating Behaviors ◽  
Health Knowledge ◽  
Bivariate Analysis ◽  
Diabetic Patients ◽  
Healthy Eating Behavior ◽  
The Impact

Diabetes mellitus sufferers have metabolic issues caused by insulin disorders which indicate hyperglycemia. Behavior related to food and eating, including the amount of calories, dietary choices, setting a meal plan, and control dietary challenges are particularly important for diabetes mellitus sufferers owing to the impact of these measures on the speed with which blood glucose levels increase. With better understanding, diabetic patients can analyze their food intake and adopt appropriate eating behaviors. Self-efficacy can affect the patient’s commitment to their health. Knowledge and self-efficacy support healthy eating behavior patterns. This study aims to identify the relationship between knowledge and self-efficacy with regards to eating behaviors among people living with diabetes mellitus. Bandura’s promotion model was provided as a conceptual framework. A simple random sampling technique was used to recruit 201 participants with diabetes mellitus type 2. Data collection was via a Demographic Questionnaire, an Eating Behavior Questionnaire, a Diabetes Knowledge Questionnaire (DKQ), and a Diabetes Mellitus Self-Efficacy Questionnaire (DMSQ). Data was analysed using univariate and bivariate analysis. The results indicate that participants’ eating behavior, knowledge, and self-efficacy were at a low level. This study also indicated a significant relationship between knowledge (p < 0,000) and self-efficacy (p < 0,00) and eating behaviors. The results provide important information to suggests that community nurses should increase the knowledge about diabetes mellitus management and use self-efficacy to design effective intervention to promote healthy eating behavior to keep blood sugar in control.   Keywords: eating behavior, knowledge, self-efficacy, diabetes mellitus

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