scholarly journals Macronutrient and calorie content in preterm and term human milk at first three week after delivery

2019 ◽  
Vol 59 (3) ◽  
pp. 130-8
Author(s):  
Dessy Shinta Murty ◽  
Hasriza Eka Putra ◽  
Sri Mulatsih ◽  
Neti Nurani ◽  
Tunjung Wibowo
Keyword(s):  
Human Milk ◽  
Protein Content ◽  
Full Term ◽  
Caloric Content ◽  
Mature Milk ◽  
The Third ◽  
Macronutrient Content ◽  
Calorie Content ◽  
Preterm Group ◽  
A Prospective Study

Background The macronutrients in human milk change dynamically and vary among mothers. Evaluation of macronutrient content in human milk is needed to improve nutritional management in preterm infants. Objective To measure the macronutrient content in preterm and full term human milk during three lactation periods in the first three weeks after delivery. Methods We conducted a prospective study among 80 mothers of infants who were hospitalized in the Department of Perinatology/NICU at Sardjito Hospital, Yogyakarta. Carbohydrate, fat, protein, and caloric content were measured using a MIRIS human milk analyzer, once per week for three consecutive weeks after delivery. A single, daytime human milk specimen was collected in the morning by directly expressing from the breast. Results Median protein, fat, carbohydrate, and caloric contents of mature milk in the preterm group were 1.40 (IQR 0.38), 3.25 (IQR 1.00), 5.70 (IQR 0.80) g/dL, and 60 kcal/dL, respectively. Median protein, fat, carbohydrate, and caloric contents of mature milk in the full term group were 1.40 (IQR 0.35), 3.30 (IQR 0.77), 5.80 (IQR 0.75) g/dL, and 62 kcal/dL, respectively, at the third week after delivery. In both groups, protein content in the first week was significantly higher than in the third week (P<0.001) after delivery. In contrast, fat content in the first week was significantly lower than in the third week (P< 0.05) after delivery, in both groups. Conclusions There are no significant differences in macronutrient and caloric content between preterm and full term human milk during the first three weeks after delivery. However, there are significant changes in fat and protein content in both preterm and full term human milk during early lactation, between the first and third weeks.

Tandem Breastfeeding and Human Milk Macronutrients: A Prospective Observational Study

2021 ◽  
pp. 089033442110038
Author(s):  
Gilad Rosenberg ◽  
Laurence Mangel ◽  
Dror Mandel ◽  
Ronella Marom ◽  
Ronit Lubetzky
Keyword(s):  
Infrared Spectroscopy ◽  
Human Milk ◽  
Protein Content ◽  
Prospective Observational Study ◽  
Carbohydrate Content ◽  
Mature Milk ◽  
Mid Infrared ◽  
Milk Samples ◽  
Macronutrient Content ◽  
In Pregnancy

Background Tandem breastfeeding is defined as two or more offspring of different ages who are breastfed by their mother at the same time. Breastfeeding during pregnancy and tandem breastfeeding have not been widely investigated. Research Aim To determine the influence of tandem breastfeeding on the macronutrient content of human milk. Methods This longitudinal study used a prospective and a retrospective group. Human milk samples from tandem-breastfeeding participants ( n = 18) were compared to samples from non-tandem-breastfeeding participants ( n = 31). Samples were collected during the last month of pregnancy (pregnancy milk), 72 hr after birth (colostrum) and 14–60 days post-delivery (mature milk). Macronutrients were measured by mid-infrared spectroscopy. Results Fat content in pregnancy milk was lower than in mature milk ( p < .01). Protein content was higher in pregnancy milk than in colostrum and mature milk ( p < .01 and p < .001, respectively). Inversely, carbohydrate content in pregnancy milk was lower than in colostrum and mature milk ( p = .02 and p < .01, respectively). Fat and energy contents in pregnancy milk of tandem-breastfeeding participants were lower than in mature milk of non-tandem-breastfeeding participants ( p < .001 and p < .01, respectively), and protein content was higher than in mature milk ( p < .001). Carbohydrate content in colostrum and mature milk of tandem-breastfeeding participants was higher than that of non-tandem-breastfeeding participants ( p < .001 for both). Conclusion Human milk produced during pregnancy had different macronutrient content than human milk produced after delivery. Colostrum and mature milk of tandem-breastfeeding participants were similar to human milk produced by non-tandem-breastfeeding participants, with the exception of carbohydrate content.

scholarly journals Levels of Cytokines (IL-1β, IL-2, IL-6, IL-8, TNF-α) and Trace Elements (Zn, Cu) in Breast Milk From Mothers of Preterm and Term Infants

2005 ◽  
Vol 2005 (6) ◽  
pp. 331-336 ◽  
Author(s):  
Bilal Ustundag ◽  
Erdal Yilmaz ◽  
Yasar Dogan ◽  
Saadet Akarsu ◽  
Halit Canatan ◽  
...  
Keyword(s):  
Trace Elements ◽  
Immune System ◽  
Human Milk ◽  
Premature Infants ◽  
Full Term ◽  
Mature Milk ◽  
Term Infants ◽  
Necrosis Factor Alpha ◽  
Significant Difference ◽  
Cytokine Levels

It has been well documented that human milk contains several immunomodulator components which are important during infant period when the newborn's immune system is still under development. In this study, we aim at examining levels of cytokines, zinc (Zn), and copper (Cu) in milk from mothers of premature and mature infants, and comparing changes during lactation periods consequently. Milk was collected from total of 40 mothers (group M: mothers of mature infants,n=20; group PM: mothers of premature infants,n=20) from four lactation stages: colostrum (0–7 days), transitional (7–14 days), mature milk (21 days), and mature milk (2nd month). Levels of cytokines (interleukin [IL]-lβ, IL-2, IL-6, IL-8, tumor necrosis factor-alpha [TNF-α]) were determined by chemiluminesence method, whereas atomic absorption spectrophotometer was used for the determination of Zn and Cu levels. Cytokine levels were determined to be high in colostrum and transient milk from mothers of full-term infants, whereas their levels were reduced drastically in the 21st day and the 2nd month milk (P<.01,P<.001). Similar trends were observed in milk from mothers of premature infants, but cytokine levels were significantly lower in colostrum compared to colostrum from mothers of mature infants (P<.01). The differences in cytokine levels were continuous in transient milk (P<.05) and mature milk (21 days) (P<.05), whereas there was no statistically significant differences between milk from both groups of mothers in the 2nd month (P>.05). Zn levels in milk from mothers of premature infants were significantly lower compared to the ones from mothers of mature infants (P<.01) and these differences continued through the 2nd month. Although Cu levels were lower in milk from mothers of premature infants, there was no statistically significant difference except colostrum (P>.05). Our results clearly demonstrate that the level of immunomodulating agents such as cytokines and trace elements in milk from mothers of premature infants is less than the level of the same agents in milk from mothers of full-term infants. Although there are commercially available products for infant feeding, human milk is still the best natural nutrient for newborns. Therefore, when premature infants are breastfed, necessary precautions such as supplemantary diets must be considered for possible infections and risks related with immune system deficiency.

scholarly journals Role of Daily Milk Volume and Period of Lactation in Nutrient Content of Human Milk: Results from a Prospective Study

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 421 ◽  
Author(s):  
Virginie Rigourd ◽  
Isabel Lopera ◽  
Florina Cata ◽  
Guy Benoit ◽  
Benedicte Jacquemet ◽  
...  
Keyword(s):  
Human Milk ◽  
Protein Content ◽  
Maternal Age ◽  
Milk Composition ◽  
Sodium Content ◽  
Lactation Period ◽  
Average Volume ◽  
Macronutrient Content ◽  
Milk Volume

Most studies assessing the macronutrient content of human milk are published retrospectively using analyzers that fail to determine sodium content and do not take into account the role of volume in milk composition. We aimed to describe macronutrient content and sodium content in human milk over time, observe any associations between them, and determine the factors associated with the evolution of milk composition. A prospective, longitudinal, monocentric study was undertaken. Contents of protein, fat, and lactose of 102 milk samples from 40 mothers were determined using a human milk analyzer and that of sodium with a flame spectrophotometer. Milk volumes along with clinical data were recorded. Protein content in the fourth quartile of volume was significantly lower than that in the first three, suggesting the existence of a volume threshold for protein content at approximately 445 mL. After multivariate analysis, it was found that maternal age, average volume, and lactation period remained significantly associated with protein content, maternal age remained significantly associated with fat content, and only average volume with sodium content. In consideration of previous findings along with our data, we suggest that extra care should be taken with fortification for feeding preterm infants when the mother’s milk volume is greater than 400–450 mL.

EVALUATION OF ADEQUACY OF DAILY ENERGY CONSUMPTION AND NUTRITIONAL VALUE OF DIETS OF JUNIOR ATHLETES

2020 ◽  
Author(s):  
Элеонора Николаевна Трушина ◽  
Оксана Константиновна Мустафина ◽  
Татьяна Николаевна Солнцева ◽  
Валерий Дмитриевич Кузнецов
Keyword(s):  
Energy Consumption ◽  
Nutritional Value ◽  
Caloric Content ◽  
Added Sugar ◽  
Junior Athletes ◽  
Calorie Content ◽  
Daily Diet ◽  
Daily Energy ◽  
Total Calorie ◽  
Recommended Level

В исследовании участвовали 20 спортсменов-юниоров (мастера спорта и кандидаты в мастера спорта) в возрасте 17-18 лет и 10 добровольцев соответствующего возраста и интенсивности физической нагрузки. В результате исследований установлено, что суммарная калорийность потребленных за сутки продуктов в основном соответствовала энерготратам спортсменов обследованных групп. Соотношение белки/жиры/углеводы в суточном рационе спортсменов свидетельствует о недостаточной квоте углеводов в соответствии с формулой оптимального питания для юных спортсменов. При этом потребление добавленного сахара у спортсменов всех категорий превышало рекомендуемый уровень (10% от калорийности суточного рациона). The study involved 20 junior athletes (masters of sports and candidates for masters of sports) aged 17-18 and 10 volunteers of the corresponding age and intensity of physical activity. As a result of the research, it was found that the total calorie content of products consumed per day basically corresponded to the energy consumption of athletes in the surveyed groups. The ratio of protein / fat / carbohydrates in the daily diet of athletes indicates an insufficient carbohydrate quota in accordance with the optimal nutrition formula for young athletes. At the same time, the consumption of added sugar in athletes of all categories exceeded the recommended level (10% of the caloric content of the daily diet).

scholarly journals The Long-Term Effect of Preterm Birth on Renal Function: A Meta-Analysis

2021 ◽  
Vol 18 (6) ◽  
pp. 2951
Author(s):  
Ju Sun Heo ◽  
Jiwon M. Lee
Keyword(s):  
Renal Function ◽  
Preterm Birth ◽  
Glomerular Filtration ◽  
Renal Plasma Flow ◽  
Meta Analysis ◽  
Full Term ◽  
Significant Difference ◽  
Preterm Group ◽  
Preterm Born

The preterm-born adult population is ever increasing following improved survival rates of premature births. We conducted a meta-analysis to investigate long-term effects of preterm birth on renal function in preterm-born survivors. We searched PubMed and EMBASE to identify studies that compared renal function in preterm-born survivors and full-term-born controls, published until 2 February 2019. A random effects model with standardized mean difference (SMD) was used for meta-analyses. Heterogeneity of the studies was evaluated using Higgin’s I2 statistics. Risk of bias was assessed using the Newcastle–Ottawa quality assessment scale. Of a total of 24,388 articles screened, 27 articles were finally included. Compared to full-term-born controls, glomerular filtration rate and effective renal plasma flow were significantly decreased in preterm survivors (SMD −0.54, 95% confidence interval (CI), −0.85 to −0.22, p = 0.0008; SMD −0.39, 95% CI, −0.74 to −0.04, p = 0.03, respectively). Length and volume of the kidneys were significantly decreased in the preterm group compared to the full-term controls (SMD −0.73, 95% CI, −1.04 to −0.41, p < 0.001; SMD −0.82, 95% CI, −1.05 to −0.60, p < 0.001, respectively). However, serum levels of blood urea nitrogen, creatinine, and cystatin C showed no significant difference. The urine microalbumin to creatinine ratio was significantly increased in the preterm group. Both systolic and diastolic blood pressures were also significantly elevated in the preterm group, although the plasma renin level did not differ. This meta-analysis demonstrates that preterm-born survivors may be subject to decreased glomerular filtration, increased albuminuria, decreased kidney size and volume, and hypertension even though their laboratory results may not yet deteriorate.

Medium- and long-chain triacylglycerols composition in preterm and full-term human milk across different lactation stages

LWT ◽  
2021 ◽  
Vol 142 ◽  
pp. 110907
Author(s):  
Tinglan Yuan ◽  
Wei Wei ◽  
Xinghe Zhang ◽  
Lei Wang ◽  
Xinyue Dai ◽  
...  
Keyword(s):  
Human Milk ◽  
Full Term ◽  
Long Chain

Problems Of Metabolic Syndrome

2021 ◽  
Vol 03 (06) ◽  
pp. 52-55
Author(s):  
Maksuda Ahmedjanovna Karimova ◽  
◽  
Dilnoza Kakhramanovna Kurbanbaeva ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Metabolic Syndrome ◽  
Lifestyle Modification ◽  
Syndrome X ◽  
Steady Increase ◽  
The Third ◽  
Calorie Content ◽  
Single Term ◽  
Life Threatening

At the beginning of the third millennium, for mankind, which overcame the epidemic of life-threatening infections during its centuries-old history, the problem of cardiovascular diseases (CVD) came to the fore in relevance among all causes of morbidity and mortality. A significant role in this was played by lifestyle modification associated with limiting physical activity, increasing the calorie content of food, and a steady increase in emotional stress. All of this potentiates the main risk factors for CVD, which are a “negative asset of progress,” namely increased blood pressure (BP), dyslipidemia, diabetes mellitus (DM) and obesity. Since 1988, after G. Reaven's Banting lecture, it is customary to designate the interconnected combination of these pathologies by the single term "metabolic syndrome X".

Gestational Hypertension and Their Impact on Activin A Concentration of the Human Milk

2021 ◽  
Author(s):  
Chiara Peila ◽  
Elena Spada ◽  
Alessandra Coscia ◽  
Stefano Sottemano ◽  
Giulia Fregnan ◽  
...  
Keyword(s):  
Breast Milk ◽  
Human Milk ◽  
Fixed Effects ◽  
Gestational Hypertension ◽  
Random Effect ◽  
Covariance Structure ◽  
Study Groups ◽  
Activin A ◽  
Mature Milk ◽  
Significant Difference

Abstract Introduction It is known that Preeclampsia affects the lactogenesis, but literature data on the effects of this syndrome on the neurobiomarkers composition and Activin A of Human Milk of the lactating mother are not available. The aim of this study is to investigate the effects of this gestational pathology on Activin A levels, a neurobiomarker known to play an important role in the development and protection of the central nervous system.Methods The women recruited in the study were divided in two different study groups: preeclamptic or healthy women. All the breast milk samples were collected using the same procedure into sterile devices BPA-free. Activin A was quantified using an ELISA test. To investigate the effect of pathology in the Activin a concentration in the 3 phases, mixed linear model with unistructural covariance structure, mother as random effect, and fixed effects were performed.Results Activin A was detected in all samples. There were no significant differences between Preeclamptic mother and Normotensive women. The only significant effect is related to the HM phase: in particular, it is significant the difference between colostrum and mature milk (p<0.01).Conclusion There is not any significant difference in Activin A breast milk composition from hypertensive and normotensive women. This result allows us to affirm that breast milk beneficial properties are maintained even if gestational hypertension occurs.

WEIGHT GAINS IN THE FIRST FOUR WEEKS OF INFANCY: A COMPARISON OF THREE DIETS

PEDIATRICS ◽  
1956 ◽  
Vol 18 (3) ◽  
pp. 362-368
Author(s):  
Ruth T. Gross ◽  
Lincoln E. Moses
Keyword(s):  
Human Milk ◽  
Statistical Methods ◽  
Full Term ◽  
Clinical Judgement ◽  
Careful Selection ◽  
Term Infants ◽  
Weight Gains ◽  
The Many ◽  
Selection Of

Four hundred seven healthy, full-term infants were divided into three groups and fed, respectively, a formula of evaporated milk and water with 5% carbohydrate; human milk; and a special modified evaporated milk designed to simulate human milk. No other foods were added to the diet. A comparison of the three groups was made, based on weight gains from birth to the end of the first 4 weeks. The conclusions refer only to weight gains; no attempt was made to determine the superiority of any particular diet. The data show no significant differences in the 4-week weight gains among the three groups of infants, although sensitive statistical methods could be validly applied to the problem. These methods are explained. The authors wish to emphasize the many variables which must be taken into account in a study of this sort; the necessity for careful selection of valid statistical methods; the importance of critical clinical judgement in the evaluation of the results.

Magnetic Resonance Imaging Evaluation of Neonates With Retinal Hemorrhages

PEDIATRICS ◽  
1992 ◽  
Vol 89 (2) ◽  
pp. 332-333
Author(s):  
WILBUR L. SMITH ◽  
RANDELL C. ALEXANDER ◽  
G. FRANK JUDISCH ◽  
YUTAKA SATO ◽  
SIMON C. S. KAO
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Abusive Head Trauma ◽  
Full Term ◽  
Resonance Imaging ◽  
Retinal Hemorrhages ◽  
Imaging Evaluation ◽  
Term Neonates ◽  
Magnetic Resonance Imaging Evaluation ◽  
A Prospective Study

Retinal hemorrhages occur frequently in association with abusive head trauma.1 The injuries are venous [See table in the PDF] in origin and, as such, are similar to the retinal hemorrhages which frequently occur in full-term neonates after vaginal delivery. Because retinal hemorrhages in child abuse frequently are associated with intracranial bleeding, we questioned the possibility of a relationship between parturitional retinal hemorrhages and concurrent intracranial injuries. To answer this question we designed a prospective study in which we performed magnetic resonance imaging on 10 randomly selected full-term neonates in whom the presence of retinal hemorrhages was confirmed on fundascopic examination by a pediatric ophthalmologist.

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