The response of plasma arginine vasopressin to 14 h water deprivation in the elderly

1984 ◽  
Vol 105 (3) ◽  
pp. 314-317 ◽  
Author(s):  
Ching Huai Li ◽  
Shao Ming Hsieh ◽  
Isamu Nagai

Abstract. The response of plasma arginine vasopressin (AVP) to 14 h water deprivation was investigated in 30 healthy elderly individuals ranging in age from 63 to 87 years, with a mean age of 76.5 years. The mean AVP concentrations, both at normal hydration and after the water deprivation test, were significantly lower than those in the young. Moreover, the post-test mean value of Uosm/Posm in the elderly increased up to 1.55 ± 0.52, which is lower than that in the young in whom the value was greater than 2. These results suggest that the aged are prone to incomplete diabetes insipidus. This pathological state might predispose to electrolyte imbalance in the elderly.

2019 ◽  
Vol 4 (1) ◽  
pp. 68
Author(s):  
Nita Fitria ◽  
Lynna Lidyana ◽  
Shelly Iskandar ◽  
Leonardo Lubis ◽  
Fidella Fidella ◽  
...  

Physical activity in the elderly will improve cognitive function. Biomolecular changes to see an increase in elderly cognitive function are characterized by an increase in the expression of plasma protein Brain Derived Nerve Factor (BDNF). Efforts to improve cognitive function can be done in Indonesian Cardio Gymnastic Serie-I . In this study the aim was to analyze the influence of Indonesian Cardio Gymnastic Serie-I three times a week for 6 weeks to Plasma Protein Expression of BDNF in Elderly. This study used a pre-experiment with the design of one group pre and post test for 27 samples of healthy elderly aged > 60 years and routinely conduct Indonesian Cardio Gymnastic Serie-I 3 times a week for 6 weeks. To determine BDNF levels taken from elderly plasma blood then measured using the Enzime Link Immunosorbent Assay (ELISA) method. To analyze the influence of Indonesian Cardio Gymnastic Serie-I to plasma protein expression of BDNF, a paired t-test was used so that the mean differences between before and after gymnastics were known. There were differences in the mean BDNF plasma protein expression before and after Indonesian Cardio Gymnastic Serie-I (2174,52 ± 700,79 VS 1981 ± 915,17 pg/ mL, p = 0,40 ; p > 0,05) with the mean difference was 192,69 which means Indonesian Cardio Gymnastic Serie-I 3 times a week for 6 weeks had no influence to plasma protein expression of BDNF because the level has decreased by 91.14% after exercising


1993 ◽  
Vol 264 (5) ◽  
pp. R877-R881 ◽  
Author(s):  
P. A. Phillips ◽  
M. Bretherton ◽  
J. Risvanis ◽  
D. Casley ◽  
C. Johnston ◽  
...  

Inhibition of dehydration-induced arginine vasopressin (AVP) secretion and thirst depends on removal of osmotic and hemodynamic stimuli as well as on preabsorptive oropharyngeal factors that reduce thirst and AVP secretion on drinking before correction of the water deficits. Plasma atrial natriuretic peptide (ANP) levels may also change with drinking. Therefore, the thirst and plasma responses to oral water loads (10 ml/kg) in 10 healthy old (64-76 yr) and young (20-32 yr) 24-h water-deprived men were investigated. After 24-h water deprivation plasma sodium, osmolality, and AVP were increased similarly in both groups (P < 0.001). Plasma ANP levels fell after dehydration similarly in both groups (P < 0.05) but were always higher in the older group (P < 0.05). However, although thirst increased in both groups (P < 0.05), this was significantly less in the elderly (P < 0.05). After the water load, thirst was reduced in both groups throughout the study (P < 0.05). However, plasma AVP fell immediately after drinking only in the young group and rose to postdeprivation levels after 15 min. Plasma AVP was not different from postdeprivation throughout in the old group and after 15 min in the young group presumably because the water load was insufficient to replace their water deficits. In the young group only, plasma ANP rose to 182 +/- 43% of postdeprivation levels at 3 min after drinking (P < 0.05). These results demonstrate reduced oropharyngeal inhibition of AVP secretion after drinking in healthy elderly men but maintained inhibition of thirst.


2017 ◽  
Vol 4 (2) ◽  
pp. 14
Author(s):  
Putri Megasari

Hepatitis has become a health problem in the world. The hepatitis virus infected many people. According to the teacher of MTsN 02 Bondowoso more than 20 students have hepatitis A viral infection. The purpose of this research was to know the differences of students' knowledge about hepatitis A before and after counseling in MTsN 02 Bondowoso 2015. This study used pre-experimental (pre-post test design). This study used stratified random sampling technique, 127 students from 270 sample involved this research,and 143 students was excluded. We used questionnaires to collect data. The results showed that the mean value of the students 'knowledge about hepatitis A before counseling in MTsN 02 Bondowoso 2015 was 83.96 with the lowest value of 37.5 and the highest value was 100. The mean value of the students' knowledge about hepatitis A after counseling in MTsN 02 Bondowoso 2015 was 93.21 with the lowest value waf 62.5 and the highest value was 100. Paired t test showed that t (-9.07) > t table (1.98), the null hypothesis (H0) was rejected. There was a difference between students' knowledge about hepatitis A before and after counseling in MTsN 02 Bondowoso 2015. This study showed that routine counseling by healthcare provider was important to prevent hepatitis A infection.; Keywords: counseling, knowledge of students, hepatitis


Nowadays, Thailand is stepping into an aging society. This research purposes developing the intelligence walking stick for the elderly in terms of the health care system by applied the IoT devices and biometric sensors in a real-time system. The heart rate, blood pressure, oxygen saturation, and temperature were measured at the finger of the elderly that holding the intelligence walking stick. All data can monitor and display on mobile devices. The intelligence walking stick system was evaluated by twenty users who are five experts and fifteen elderly in Ratchaburi province. As a result of the mean value at 4.88 and 4.85 by experts and elderly, respectively. It could be said that the development of intelligence walking stick by using IoT can help and improve the daily living of the elderly at the highest level.


2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii442-iii442
Author(s):  
Tatsuki Oyoshi ◽  
Shingo Fujio ◽  
Nayuta Higa ◽  
Hajime Yonezawa ◽  
Koji Yoshimoto

Abstract INTRODUCTION Intellectual assessment in children with craniopharyngioma after tumor removal is still unknown. We assessed intellectual development in children who underwent microsurgical resection in our institute over the last twelve years. MATERIALS AND METHODS Ten children among 41 patients with craniopharyngioma treated and followed at Kagoshima University Hospital between 2007 and 2019 were reviewed. We also assessed intellectual development in 10 years or younger children with craniopharyngioma one year after tumor removal. Intelligence was assessed using the Wechsler Intelligence Scale for Children-Fourth Edition (WISC-Ⅳ). RESULTS Ten children underwent microsurgical tumor removal. The mean age at surgery was 5.8 (range 1–10) years. Transcranial approach was performed in 8 children, transsphenoidal approach in two children. The mean follow up period was 110 months. Gamma knife surgery (GKS) was performed in 6 children less than 6 months after first surgery. Regional recurrences occurred in 5 children, and additional GKS was performed in four children, second microsurgical removal in one child. Severe obesity with a transient electrolyte imbalance occurred in one child. Eight children with GH deficiency underwent GH replacement therapy. Eight children were assessed working memory index (WMI), processing speed index (PSI), Perceptual reasoning index (PRI), and verbal comprehension index (VCI) using WISC 4. Each mean value of WMI, PSI, and PRI was lower than VCI, except for 2 children with normal full scale intelligence quotient. CONCLUSION WMI, PSI and PRI in children with intellectual disabilities were lower tendency than VCI after surgical removal of craniopharyngiomas in the present study.


The purpose of the research was to investigatethe effect of activity-based games on the academic achievement of graduate-level pupils in social sciences.An experimental research design with a pre-and post-test control group was used in this study. As pre-test and post-test, MCQ achievement tests containing 70 items were used as research methods for data collecting. The initial stage in this initiative was to collect data on what inspires children to learn. Both groups took a pre-test, and the results were tallied.The project's second phase was to study the effects of variousactivities on academic achievement. Both groups were given an MCQ performance test. The T-test was used to analyze the data. The findings of this study demonstrated that, compared to the control group, mostpupils'marks improved in the experimental group. The mean value showedthat experimental group participants scored 18.77on the post-test, while control group students scored 16.21. According to a post-lesson poll, most students regarded activity-based games to be more engaging than lecture-based instruction.


2017 ◽  
Vol 1 ◽  
pp. 54
Author(s):  
Arita Destianingsih ◽  
Ari Satria

The aim of this study was to know the effectiveness of the use of alphabet cards game as interesting tool to explain vocabularies and it make it easier to remember their meanings. This study belongs to the quasi experimental research and presents pre-test, post test and to investigate the effect of using alphabet cards game on vocabulary mastery of commercial business administration students. The participants were the students from commercial business administration students at the third semester (N=54) of State Polytechnic Bengkalis and divided into two groups. Both groups were taught vocabulary, however, the experimental group students who are exposed to alphabet cards game and the controlled group students who received conventional method. Pre-test and post-test were given to both experimental group students and controlled group students. The score of the vocabulary tests were compared through independent sample t-test. The mean value of pre-test of experimental class was 61.35, while the control class was 52.23. After learning using alphabet card games in experimental class the mean value obtained in post-test was 78.85, while in control class was 59.04.  The improved of learning outcomes can be seen from the level of significance was 0.000 and it was lower than t test 0.000<0.05.  It means that the hypothesis null is not accepted. Therefore, it can be concluded that the score of the students in learning vocabulary between the experimental group and control group was significantly different. The experimental group students who learned vocabulary using alphabet cards game had increased their vocabulary mastery.


2021 ◽  
Vol 4 (1) ◽  
pp. 27
Author(s):  
Muhammad Aulia U H ◽  
Iswinarno Doso Saputro ◽  
Magda Rosalina Hutagalung

Background: The incidence of burns in Indonesia progressively increases with the increase in its population and industries. From January to September 2000, 158 patients were treated in the burn unit of Dr Soetomo Hospital with a mortality rate reaching 5,8%. Burns have a direct effect in causing both local and systemic changes in the body, not occurring in other injuries. In severe burns, a hypermetabolic state can occur, which increases cardiac workload and causes muscle atrophy and other morbidities. The purpose of this study is to examine the effect of propranolol on the hypermetabolic state in severely burned patients by measuring various clinical & laboratory parameters.Methods : This is an experimental study using pre and post test control group design with the objective of assessing the treatment outcome with oral propranolol given in 15 consecutive days for burn patients involving 25%- 60% TBSA. Measurements were taken three times, on day 0, 7 and 14.Results : Obtained 16 samples divided into 2 groups. In the treatment group, there was a significant decrease in CRP levels on days 0, 7 and 14 (p <0.05). The Mid Arm Circumference variable did not obtain a significant decreasing on days 0, 7 and 14. The albumin level studied showed a significant decreasing on day 0 & 7 days with a value of p = 0.045. From the comparison between the two groups, there were significant differences in CRP levels on days 0 & 14, with the mean value of the treatment group -5.12 + 2.88 and the mean value of the control group 2.86 + 7.37, and the value of p = 0.019.Conclusions: This study successfully proved that the administration of propranolol can overcome the effects of hypermetabolism which is characterized by decreasing in CRP levels.


2021 ◽  
Vol 3 (3) ◽  
pp. 426-431
Author(s):  
Destri Siti Juleha ◽  
Deviani Utami ◽  
Ade Utia Detty

ABSTRACTBackground: Erythrocytes Sedimentation Rate (ESR) is a test to determine the rate of erythrocytes settling blood containing anticoagulants in a vertical tube within a certain time. ESR is generally used to check and monitor for tissue damage, inflammation and indicate disease. ESR examination can be done by manual and automatic methods. LED levels in pulmonary TB patients generally have increased.Objectives: Knowing the difference in the measurement results of the erythrocytes sedimentation rate (ESR) between the Westergen manual and automatic methods in patients with pulmonary tuberculosis.Methods: Laboratory experiments with a post-test-only approach. The number of samples was 30 people and was taken by purposive sampling. The research data were obtained from the results of the ESR examination using the Westergren manual and automatic methods. Results: Examination of the sedimentation rate of healthy respondents used the Westergren method had an average of 9,40 mm/hour while in the automatic method 10,15 mm/hour. The examination of sedimentation rate of pulmonary tuberculosis respondents with the Westergren method had an average of 66,13mm/hour, while the Automatic method was 67,80 mm/hour. There was no significant difference in the mean value of ESR between the measurement method used manual Westergren and Automatic methods in patients with pulmonary tuberculosis ( p = 0,878).   Conclusion: There is no significant difference in the mean value of ESR between measurements using the manual Westergren method and automatic in patients with pulmonary tuberculosis. Keywords: Erythrocytes Sedimentation Rate, Method, Westergren, Automatic  PERBANDINGAN NILAI LAJU ENDAP DARAH ANTARA PENGUKURAN METODE MANUAL WESTERGREN DAN ALAT AUTOMATIK PADA SAMPEL DARAH SITRAT PENDERITA TB PARU DI RSUD. Dr. DRADJAT PRAWIRANEGARA SERANG TAHUN 2020 Latar Belakang: Laju Endap Darah (LED) adalah pemeriksaan untuk menentukan kecepatan eritrosit mengendap dalam darah yang berisi antikoagulan pada suatu tabung vertikal dalam waktu tertentu. LED pada umumnya digunakan untuk mendeteksi dan memantau adanya kerusakan jaringan, inflamasi dan menunjukan adanya penyakit. Pemeriksaan LED dapat dilakukan dengan metode manual dan automatik. Kadar LED pada penderita TB Paru umumnya mengalami peningkatan.Tujuan: Mengetahui perbedaan hasil pengukuran Laju Endap Darah (LED) antara metode manual Westergen dan Automatik pada Penderita TB Paru. Metodologi: Eksperimen laboratorik dengan pendekatan post test only. Jumlah sampel 30 orang dan diambil dengan purposive sampling. Data penelitian diperoleh dari hasil pemeriksaan LED menggunakan metode manual Westergren dan Automatik.  Hasil: Pemeriksaan Laju Endap Darah pada responden sehat metode Westergren memiliki rata-rata 9,40 mm/jam sedangkan pada metode Automatik 10,15 mm/jam. Pemeriksaan Laju Endap Darah pada responden TB Paru metode Westergren memiliki rata-rata 66,13 mm/jam sedangkan pada metode Automatik 67,80 mm/jam. Tidak terdapat perbedaan rata-rata nilai LED yang signifikan antara pengukuran menggunakan metode manual Westergren dan Automatik pada penderita TB Paru (p = 0,878). Kesimpulan: Tidak terdapat perbedaan rata-rata nilai LED yang signifikan antara pengukuran menggunakan metode manual Westergren dan Automatik pada penderita TB Paru.Kata kunci: Laju Endap Darah, Metode, Westergren, Automatik


Author(s):  
Noor Asmina Binti Mohd Rashid ◽  
Shaharuddin Bin Md Salleh ◽  
Norah Binti Md Noor

<p class="0abstract"> In the past, Jawi script was the main medium of intermediation in Malaya. However, since the emergence of the Roman script, the use of Jawi script has been marginalized causing less awareness among some of the younger generation on the uniqueness of Jawi script. Therefore, a mobile application has been developed to attract students to explore Jawi script especially the spelling of Jawi words. This Jawi Spelling Skills mobile application used constructivism approach and ADDIE model during the development process. This study used quantitative one group pre-test and post-test research design that conducted among 20 students of a primary school. The result shows that the mean value of the post-test was higher than the pre-test which is 89.00 while the percentage of students who liked the Jawi Spelling Skills mobile learning application was high. In conclusion, the application of Jawi Spelling Skills Mobile Learning Application able to attract students to learn Jawi indirectly raised the dignity of Jawi script in the future besides supporting the 21st- century education.</p>


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