scholarly journals Comparative Literature Study of Bligo Fruit Extract (Benincasa hispida (Thunb) Cogn) and Bitter Melon (Momordica charantia L.) Extract on the Minimum Inhibition of Salmonella typhi Bacteria

2021 ◽  
Vol 17 (2) ◽  
pp. 167
Author(s):  
Mei Rizqi Putri Afifah ◽  
Noer Kumala Indahsari
Keyword(s):  
Salmonella Typhi ◽  
Momordica Charantia ◽  
Bitter Melon ◽  
Literature Study ◽  
Fruit Extract ◽  
Benincasa Hispida ◽  
Narrative Literature ◽  
Narrative Literature Review ◽  
Inhibitory Power ◽  
Comparative Literature Study

Abstract: Salmonella typhi is a gram-negative bacteria species that causes typhoid fever. Salmonella typhi is sensitive to antibiotics such as amoxicillin, chloramphenicol, ciprofloxacin, and cotrimoxazole. However, there has been some increase in antibiotic resistance, so there is a need for new antibacterials that do not have a resistance effect to treat infection. Bligo fruit (Benincasa hispida (Thunb) Cogn) and bitter melon (Momordica charantia L.) contain saponins, tannins, flavonoids, alkaloids, and triterpenoids which have antibacterial power. The purpose of this study was to compare the effectiveness of the bligo fruit extract (Benincasa hispida (Thunb) Cogn) and bitter melon extract (Momordica charantia L.) on the minimum inhibition of Salmonella typhi bacteria. The method used is narrative literature review. The results of the journal study showed that the extract of bitter melon (Momordica charantia L.) was more effective in inhibiting Salmonella typhi bacteria than the extract of bligo (Benincasa hispida (Thunb) Cogn) with a minimum inhibitory power at a concentration of 20%, namely 8.5 mm. Keywords: Bligo Fruit (Benincasa hispida (Thunb) Cogn), Bitter Melon (Momordica charantia L.), Salmonella typhi.

scholarly journals Transformation of entrepreneur education programs (EEPS) of Indonesia’s higher education

2021 ◽  
Vol 10 (1) ◽  
pp. 180-188
Author(s):  
Erna Handayani ◽  
Siswoyo Haryono ◽  
Akhmad Darmawan
Keyword(s):  
Higher Education ◽  
Education Program ◽  
Entrepreneurship Education ◽  
Literature Study ◽  
Research Information ◽  
Analysis Technique ◽  
Collection Data ◽  
Narrative Literature ◽  
Narrative Literature Review

The Entrepreneurship Education Program (EEPs) of Indonesia’s higher education has not been effective. The study aims to identify the extent to which EEPs in Indonesia was developed and propose several alternative schemes. The research uses the methodology of traditional narrative literature review and interviews with young entrepreneurs as the output of the EEPs higher education program in Indonesia. The analysis technique is done with an interactive model with steps of data collection, data reduction, data presentation, verification, and conclusions.  The literature study is intended for the latest research information that evaluates the effect of EEPs on the formation of EM and the formation of new entrepreneurs. Furthermore, the information is verified by the results of the interview data processing. Entrepreneurship education for multidisciplinary students, business incubators, funding provision, and program sustainability studies is the result of research as a proposal for the development of higher education EEPs. This program is part of a long-term solution to addressing labor problems in Indonesia.

scholarly journals STRATEGY TO MASK THE BITTER TASTE OF MOMORDICA CHARANTIA EXTRACT USING ALGINATE–GELATIN BEADS

2018 ◽  
Vol 10 (1) ◽  
pp. 381
Author(s):  
Sutriyo . ◽  
Raditya Iswandana ◽  
Fauzana Fauzi
Keyword(s):  
Particle Distribution ◽  
Bitter Taste ◽  
Momordica Charantia ◽  
Process Efficiency ◽  
Cross Linking ◽  
Ionic Gelation ◽  
Bitter Melon ◽  
Fruit Extract ◽  
Round Shape ◽  
Melon Fruit

Objective: This study is aimed to develop a strategy to mask the bitter taste of Momordica charantia Linn. extract using alginate–gelatin beads.Methods: Beads of bitter melon fruit extract (M. charantia Linn) were prepared using an ionic gelation method in which cross-linking occurs betweensodium alginate and calcium chloride that serves to mask the bitter taste. Beads were prepared using sodium alginate (1.5% w/v) with variousconcentrations of bitter melon fruit extract (1:2, 1:1, and 1:0.5), gelatin (2% w/v), and CaCl2 3%. The obtained beads were then characterized bothphysically and functionally, and their morphology, process efficiency, particle distribution, swelling index, and water content were recorded.Results: Formula 1 beads, with a 1:2 ratio of extract: alginate, displayed a near-round shape with a diameter of 600–1 200 μm, a swelling index of113.21%, and a moisture content of 15.34%. In addition, these beads were able to significantly cover the bitter taste (p<0.05).Conclusion: Formula 1 beads with a 1:2 ratio of extract: alginate can effectively mask the bitter taste of M. charantia Linn.

scholarly journals Effect of Ethanol Concentration on Antibacterial Activity of Bligo Fruit Extract (Benincasa hispida Thunb) to Salmonella typhi

2018 ◽  
Vol 5 (3) ◽  
pp. 76
Author(s):  
Fhahri Mubarak ◽  
Sartini Sartini ◽  
Dia Purnawanti
Keyword(s):  
Antibacterial Activity ◽  
Medicinal Plants ◽  
Typhoid Fever ◽  
Ethanol Concentration ◽  
Salmonella Typhi ◽  
Fruit Extract ◽  
Activity Test ◽  
Benincasa Hispida ◽  
Agar Method

Bligo fruit (Benincasa hispida Thunb) is one of medicinal plants that used to cure typhoid fever which caused by Salmonella typhi bacteria. The aim of this research is to find ont the effect of ethanol concentration as a solvent from Bligo fruit (Benincasa hispida Thunb) extracts as an antibacterial, especially to Salmonella typhi. This simplicia was being extracted with 96% ethanol, 70% ethanol, and 50% ethanol by using maceration method for 3x24 hours. The antibacterial activity test was done by diffusion of agar method to the MHA medium by obserring the resistor zone which formed from 96% ethanol, 70% ethanol and 50% ethanol. The diametres that have been obtained are 6,815 mm for 96% ethanol, 25,223 mm for 70% ethanol while for 50% ethanol there is no resisten zone can be seen. From the result canbe conclude that the best concentration of ethanol that has a great potencial as resistor to Salmonella typhi bacteria is the Bligo fruit (Benincasa hispida Thunb) extracts of 70% ethanol.Key words: Bligo fruit (Benincasa hispida Thunb), Antibacterial, Salmonella typhi.

scholarly journals FORMULASI DAN UJI EFEKTIVITAS GEL EKSTRAK BUAH PARE (Momordica charantia L) Terhadap BAKTERI Staphylococcusepidermidis dan Propionibacterium acnes PENYEBAB JERAWAT

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Nur Ain Thomas ◽  
Widy Susanti Abdulkadir ◽  
Mega Agustiwi Mohi
Keyword(s):  
Staphylococcus Epidermidis ◽  
Propionibacterium Acnes ◽  
Scientific Data ◽  
Momordica Charantia ◽  
Bitter Melon ◽  
Fruit Extract ◽  
Propionibacterium Acne ◽  
Extract Concentration ◽  
Irritation Test ◽  
Bitter Fruit

FORMULASI DAN UJI EFEKTIVITAS GEL EKSTRAK BUAH PARE (Momordica charantia L) Terhadap BAKTERI Staphylococcusepidermidis dan Propionibacterium acnes PENYEBAB JERAWAT Nur Ain Thomas1), Widysusanti Abdulkadir1), Mega Agustiwi Mohi1) 1)Jurusan Farmasi, Fakultas Olahraga dan KesehatanUniversitas Negeri Gorontalo ABSTRACT Acne is a skin disease in the form of inflammation in the layer of polysebaseus triggered by the bacteria Staphyloccoccus epidermidis and Propionibacterium acnes. One plant that is empirically and based on scientific data has anti-acne properties is bitter melon (Momordica charantia L). In pare fruit extract contains flavonoids which are thought to be able to act as active compounds in the form of anti-acne. This study aims to formulate bitter melon extract as an anti-acne gel and determine the inhibition of bitter melon extract gel against acne-causing bacteria, namely Staphylococcus epidermidis and Propionibacterium acne. Pare fruit extract gel with 3 variations of extract concentration, namely 5%, 7.5% and 10%. Evaluation of gel preparations included organoleptic test, homogeneity, spreadability, pH, viscosity, and irritation test. Data analysis using Oneway ANOVA. Based on the results of the research conducted, it can be concluded that bitter fruit extract (Momordica charantia L) can be formulated as an anti-acne gel, and the preparation of bitter fruit extract gel (Momordica charantia L) at a concentration of 10% has a inhibition of 10 mm against Staphylococcus epidermidis and 7, 1 mm against the bacterium Propionibacterium acne which is included in the medium category. Keywords: Acne, Extract, Gel , Stahpylococcus epidermidis, Propionibacterium acnes  ABSTRAK Jerawat merupakan penyakit kulit berupa peradangan pada lapisan polisebaseus yang dipicu oleh bakteri Staphyloccoccus epidermidis dan Propionibacterium acnes. Salah satu tanaman yang secara empiris dan berdasarkan data ilmiah memiliki khasiat antijerawat adalah buah pare (Momordica charantia L). Dalam ekstrak buah pare terkandung flavonoid yang diduga dapat berperan  sebagai senyawa aktif sedian antijerawat. Penelitian ini bertujuan untuk  memformulasikan ekstrak buah pare sebagai gel antijerawat dan menentukan daya hambat gel ekstrak buah pare terhadap bakteri penyebab jerawat yaitu Staphylococcus epidermidis dan Propionibacterium acne. Gel ekstrak buah pare dengan 3 variasi konsentrasi ekstrak yaitu 5%, 7,5% dan 10%. Evaluasi sediaan gel meliputi uji organoleptik, homogenitas, daya sebar, pH, viskositas, dan uji iritasi.Analisis data menggunakan ANOVA Oneway. Berdasarkan hasil penelitian yang dilakukan maka dapat disimpulkan bahwa ekstrak buah pare (Momordica charantia L) dapat diformulasikan sebagai gel antijerawat, dan sediaan gel ekstrak buah pare (Momordica charantia L) pada konsentrasi 10% mempunyai daya hambat 10 mm terhadap bakteri Staphylococcus epidermidis dan 7,1 mm terhadap bakteri Propionibacterium acne yang termasuk dalam kategori sedang.Kata Kunci :Jerawat, Ekstrak Buah Pare, Gel, Stahpylococcus epidermidis, Propionibacterium acnes  

scholarly journals Perbandingan kualitas spermatozoa tikus wistar (rattus norvegicus) yang diberi ekstrak buah pare (momordica charantia L) dengan ekstrak biji pepaya (carica papaya L)

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Kyrie E. Wenur ◽  
Lusiana Satiawati ◽  
Lydia Tendean
Keyword(s):  
Rattus Norvegicus ◽  
Wistar Rats ◽  
Carica Papaya ◽  
Seed Extract ◽  
Momordica Charantia ◽  
Bitter Melon ◽  
Fruit Extract ◽  
Treatment Groups ◽  
Papaya Seeds

Abstract: Male participation in contraception is still lacking. Pare (Momordica charantia L) is known having an inhibitory effect spermatogenesis and seeds of papaya (Carica papaya L) contain the alkaloid compounds that are anti-fertility, both can be used as a male contraceptive. The purpose of this study was to determine sperm quality comparison Wistar rats (Rattus norvegicus) were given a fruit extract of pare (Momordica charantia L) with the seed extract of papaya (Carica papaya L). The research used a completely randomized experimental design. There are nine samples of Wistar rats (Rattus norvegicus) males were divided into three groups and one group consisting three Wistar rats. Over the past 50 days, extracts of pare (Momordica charantia L) is given to the group 1 at 70mg / kg/day, while in the group 2 given seed extract of papaya (Carica papaya L) of 70mg / kg/day and the control group was given no treatment. The results showed significant differences in sperm motility among the treatment groups 1 with extract of bitter melon fruit (Momordica charantia L) and 2 treatment groups with the extract of papaya seeds (Carica papaya L), namely a decrease in sperm motility (p = 0.002). Conclusion, the fruit extract of bitter melon (Momordica charantia L) and seed extract of papaya (Carica papaya L) affects the quality of spermatozoa.Keywords: pare, papaya seeds, quality of spermatozoa. Abstrak: Partisipasi pria dalam menggunakan alat kontrasepsi masih sangat kurang. Pare (Momordica charantia L) diketahui memiliki efek penghambatan spermatogenesis dan biji pepaya (Carica papaya L) mengandung senyawa alkaloid yang bersifat antifertilitas, keduanya dapat digunakan sebagai bahan kontrasepsi pria. Tujuan penelitian ini adalah mengetahui perbandingan kualitas spermatozoa tikus wistar (Rattus norvegicus) yang diberi ekstrak buah pare (Momordica charantia L) dengan ekstrak biji pepaya (Carica papaya L). Penelitian ini menggunakan metode penelitian eksperimental dengan menggunakan rancangan acak lengkap. Sampel yang digunakan adalah sembilan tikus wistar (Rattus norvegicus) jantan yang dibagi menjadi tiga kelompok dan satu kelompok terdiri dari tiga ekor tikus wistar. Selama 50 hari, ekstrak buah pare (Momordica charantia L) diberikan pada kelompok perlakuan 1 sebesar 70mg/kgBB per hari, sedangkan pada kelompok perlakuan 2 diberikan ekstrak biji pepaya (Carica papaya L) sebesar 70mg/kgBB per dan kelompok kontrol tidak diberikan perlakuan. Hasil penelitian menunjukan adanya perbedaan signifikan pada motilitas spermatozoa antara kelompok perlakuan 1 dengan pemberian ekstrak buah pare (Momordica charantia L) dan kelompok perlakuan 2 dengan pemberian ekstrak biji pepaya (Carica papaya L) yaitu penurunan motilitas spermatozoa ( p = 0,002).Kesimpulan, ekstrak buah pare (Momordica charantia L) dan ekstrak biji pepaya (Carica papaya L) berpengaruh terhadap kualitas spermatozoa. Kata kunci: buah pare, biji pepaya, kualitas spermatozoa

scholarly journals Bitter melon (Momordica charantia) fruit extract ameliorates methotrexate‐induced reproductive toxicity in male rats

2021 ◽  
Author(s):  
Fatma KANPALTA ◽  
Dilek OZBEYLI ◽  
Ali SEN ◽  
Özge CEVIK ◽  
Göksel SENER ◽  
...  
Keyword(s):  
Reproductive Toxicity ◽  
Momordica Charantia ◽  
Male Rats ◽  
Bitter Melon ◽  
Fruit Extract

scholarly journals FORMULASI DAN UJI STABILITAS FISIK SEDIAAN TABLET EKSTRAK BUAH PARE (Momordica charantia L.) SECARA GRANULASI BASAH

2019 ◽  
Vol 2 (1) ◽  
pp. 25
Author(s):  
Ira Nur Fadhilah ◽  
Dwi Saryanti
Keyword(s):  
Physical Stability ◽  
Momordica Charantia ◽  
Wet Granulation ◽  
Bitter Melon ◽  
Fruit Extract ◽  
Glucose Levels ◽  
Binding Material ◽  
Gelatin Concentration ◽  
Bitter Fruit ◽  
Melon Fruit

<p>Bitter melon fruit is one type of medicinal plant used by the community. Charantin is one of the efficacious compounds contained in bitter melon fruit and can be used to reduce glucose levels in the blood. Tablets have advantage that are easy to consume and exactly the size, so in this study bitter melon is made from tablet preparations. The purpose of this study was to determine the concentration of gelatin binder which can produce tablets of bitter fruit extract (<em>Momordica charantia</em> L.) with good physical quality, and to determine the effect of gelatin as a binder on the physical stability test of bitter melon extract tablets (<em>Momordica charantia</em> L.) making bitter melon extract tablets is by wet granulation method, because the active ingredient of bitter melon fruit is not resistant to warming above 600C. Formulation tablets of bitter melon extract (<em>Momordica charantia</em> L.) with gelatin binder at a concentration of 5%, 7.5%, 10% able to produce tablets that meet the requirements of tablet physical examination for 28 days. Gelatin binding concentration has an effect on the physical properties of tablets, the best concentration of gelatin binder is formula III with 10% gelatin concentration. The higher the concentration of the binding material, the higher the hardness, and fragility decreases.<br />Keywords: Bitter Melon Extract (<em>Momordica charantia</em> L.), Gelatin binder, Wet Granulation.</p>

scholarly journals Uji Aktivitas Antibakteri Ekstrak Etanol Daun Pare (Momordica charantia L.) Terhadap Bakteri Staphylococcus aureus ATCC 25923

2021 ◽  
Vol 1 ◽  
pp. 1598-1604
Author(s):  
Kholila Rizqiana ◽  
Dwi Bagus Pambudi
Keyword(s):  
Staphylococcus Aureus ◽  
Leaf Extract ◽  
Momordica Charantia ◽  
Diffusion Method ◽  
Bitter Melon ◽  
Disc Diffusion ◽  
Clear Zone ◽  
Disc Diffusion Method ◽  
Chemical Content ◽  
Inhibitory Power

AbstractBitter gourd as a traditional medicine has a chemical content in its leaves that are useful as antimicrobials and as antioxidants. According to research by Tessa Undap, 2017 shows that bitter melon leaves have an inhibitory power against the growth of Staphylococcus aureus bacteria by inhibiting protein synthesis. The purpose of this study was to determine the antibacterial activity of bitter melon leaf extract (Momordica charantia L.). The research method used in this study is the disc diffusion method. Data was collected by measuring the diameter of the clear zone formed in each treatment. The antibacterial results showed that the 9% extract concentration had the highest inhibitory power.Keywords: Antibacterial, Pare Leaf Extract, Granules, Staphylococcus aureus. AbstrakTanaman pare sebagai obat tradisional memiliki kandungan kimia dalam daunnya yang bermanfaat sebagai antimikroba dan sebagai antioksidan. Menurut penelitian oleh Tessa Undap, 2017 menunjukkan bahwa daun pare mempunyai daya hambat terhadap pertumbuhan bakteri Staphylococcus aureus dengan cara menghambat sintesis protein. Adanya kandungan flavonoid dalam daun pare dapat menghambat pertumbuhan bakteri Staphylococcus aureus yang dapat mengkoagulasi protein pada sel bakteri. Tujuan dari penelitian ini yaitu untuk mengetahui aktivitas antibakteri yang terkandung dalam ekstrak daun pare (Momordica charantia L.). Metode penelitian yang digunakan dalam penelitian ini yaitu metode difusi cakram disk. Pengumpulan data dilakukan dengan cara mengukur diameter zona bening yang terbentuk pada setiap perlakuan. Hasil antibakteri yaitu menunjukkan bahwa konsentrasi ekstrak 9% mempunyai daya hambat paling tinggi.Kata kunci: Antibakteri, Ekstrak Daun Pare, Granul, Staphylococcus aureus.

Giving and receiving written feedback on research reports: a narrative review and guidance for supervisors and students

2020 ◽  
Vol 3 (2) ◽  
Author(s):  
Kerith Duncanson ◽  
David Schmidt ◽  
Emma Webster
Keyword(s):  
Research Report ◽  
Emotional Impact ◽  
Written Feedback ◽  
Supervisory Relationship ◽  
Factors Associated ◽  
Researcher Development ◽  
Teacher Student ◽  
Narrative Literature ◽  
Narrative Literature Review ◽  
Educational Component

PurposeWritten feedback on research-related writing is an important educational component of novice researcher development. Limited evidence exists to inform effective written feedback, particularly in relation to research reports by novice researchers. The aim of this narrative literature review was to explore supervisor and novice researcher perspectives on the provision of written feedback, particularly in the context of their evolving supervisory relationship. MethodsA systematic search of peer-reviewed journals in educational and health databases was undertaken for the terms ‘written feedback’ and ‘research report’, from January 2001 to August 2020. Identified literature was critiqued for methodological quality. Findings were coded, grouped and described as themes. Next, the themes and their parts were applied to the development of a two-part written feedback checklist that includes separate but related recommendations for supervisors and novice researchers.FindingsFrom 35 included papers, the four main themes that related to written feedback on research reports by novice researchers were: the emotional impact of receiving or giving written feedback; written feedback in the supervisory power dynamic; communicating written feedback; and the content and structure of written feedback. The changing nature and complexity of factors associated with written feedback from research supervisors reflected the transition from a supervisory relationship to a peer relationship. The checklist developed from the synthesised data is intended to provide guidance for supervisors and students about their respective and shared responsibilities within a supervisory relationship.  ImplicationsIncreased awareness of the characteristics, roles and impact of written feedback will assist supervisors of novice researchers to provide effective written feedback, and for students to effectively utilise written feedback. Progression of written feedback throughout the supervisory period is proposed as a means of transitioning from a teacher-student to a peer researcher relationship. 

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