Predictive Factor for Emotional Fragility in Early Stage Melanoma Diagnosis 

Author(s):  
Dina Giacomo ◽  
Federica Guerra ◽  
Jessica Ranieri ◽  
Eleonora Cilli

Abstract Objective. Melanoma patients remain at risk of disease progression for many years after diagnosis. Psychological distress, depression and anxiety are emotional conditions that negatively influence both the patients’ quality of life and the clinical course of the disease, laying down for a slow recovery as well as for an increase in comorbidity. Aim of the study was to analyze the psychological needs of young and adult patients diagnosed with early stage melanoma by gender sensitivity. Methods. A sample of 92 patients (age range 18-55 years) with diagnosis of melanoma stage T0-T1a-T1b participated in the study. The examined emotional variables were: psychological distress, depression, stress, anxiety, metacognitions and body self-perception. Results. The results highlighted significant gender differences: females appeared psychologically more vulnerable than males; another interesting point was no aging depending. Female emotional pattern showed higher anxiety, and psychological distress associated to lower positive self-perception of body image. No significant difference among cancer staging, as well as no interaction effect and neither significant covariance by age.Conclusion. Prevention and intervention protocols must be adapted taking into account gender differences in the adoption of preventive behaviors and compliance with medical recommendations

Author(s):  
Dina Di Giacomo ◽  
Jessica Ranieri ◽  
Federica Guerra ◽  
Eleonora Cilli ◽  
Valeria Ciciarelli ◽  
...  

2021 ◽  
Author(s):  
Mehrdad Abdullahzadeh ◽  
Narjes Khosravi

Abstract PurposeThe family of leukemia patients, due to their caring role, often feel psychological distress. This paper describes the efficacy of a designed family-need-based program on relieving depression, anxiety, and stress of family caregivers of leukemia patients by meeting the specific psychological needs of caregivers.MethodsIn this clinical trial, 64 family caregivers of leukemia patients referring to a medical center in Iran were recruited by convenience sampling and divided into study and control groups randomly. The study group attended a designed need-based program. The control group did not receive the intervention. Stress, anxiety, and depression before, right after, and one month after the intervention in family caregivers were compared using DASS-42. Data were analyzed using descriptive and inferential statistics; the significance level adopted was 5%.ResultsBefore the intervention, the mean score of depression, anxiety, and stress scale in both study and control groups showed no considerable difference (P > 0.05). After the intervention, the mean score of DASS-42 revealed a significant difference between the two groups and the study group did better on outcomes (P < 0.001).ConclusionThis family-need-based program can decrease the level of stress, anxiety, and depression of the family caregivers of leukemia patients and may potentially alleviate the psychological distress of family caregivers over their caring role.Trial registration number: IRCT2013093011895N2. Date of registration: 2014-05-06


Author(s):  
Ranjini Karthikeyan ◽  
Amiya Bhaumik

Body self-relation is a multidimensional construct defined by persons" perceptions of and attitudes about their body. Body image does not simply reflect the biological enrichment of the individual or the feedback received from the significant others. The way you perceive about your body is your cognitive body image. This can lead to excessive concern with body shape and weight. Behaviors in which you relate as a result of your body image encompass your behavioral body image. A study based on the gender differences in body relation relating to young adults rating the comparison in perception of both male and female data. Hundred participants of both male and female took part in answering the by Multidimensional body selfrelations questionnaire (MBSRQ-AS). Results demonstrated by Mann Whitney U test revealed that there is significant difference between male and female young adults in their relation to body self, p<0.05, (2- tailed) in appearance orientation. There is no statistical sig.>0.05 differences in the other dimensions. Therefore, this study rejects the null hypothesis in (dimension) appearance orientation and accepts the null hypothesis (dimensions) in appearance evaluation, body area satisfaction, overweight preoccupation and self-classified weight. Keywords: body self-relation; gender differences


2018 ◽  
Vol 12 (2) ◽  
pp. 3-8
Author(s):  
Nupur Pandit ◽  
Shovana Banik ◽  
Shilpi Kumari Prasad ◽  
Piya Majumdar ◽  
Oly Banerjee ◽  
...  

Background: This study was based on gender differences in male and female trained tennis players. Aim of the study: The aim of this study was to determine the extent that physical training could minimize the gender differences in lung capacities in trained tennis players aged 14–17 years. Material and methods: The participants were ten male and seven female lawn tennis players, with a mean ± standard deviation (SD) age of 15.5 ± 1.27 and 14.43 ± 1.13 years, respectively. Physical characteristics and lung volumes were measured on the same day for each participant. Data were presented as mean ± SD, and Student’s t-test to compare the measured variables was performed. Results: Differences between genders were insignificant in terms of age (years), weight (kg), body fat (%), lean body mass (kg) and chest circumference (cm). However, height (cm), and W/H ratio were significantly (p < 0.05) higher in male tennis players in comparison to female players. Insignificant differences were found for TV (L), SVC (L), FVC (L), FEV1 (L), FEV1/FVC (%), FEF25-75% (L/s), PEF (L/s) and MVV (L/min). The only significant difference (p < 0.05) in lung function measures between male and female trained tennis players was for PIF (L/s). Conclusions: Male tennis players were taller than female tennis players of same age range, which might be advantageous for males while playing. Insignificant differences between male and female players in the various lung variables measured indicated that the influence of height and gender differences could be minimized by proper training during puberty. A significantly higher PIF in male players indicated stronger and more powerful inspiratory muscle activity compared with female tennis players.


2021 ◽  
Vol 8 (7) ◽  
pp. 99-104
Author(s):  
Erma Wahyuni ◽  
Herman Hariman ◽  
Deri Edianto

Ovarian cancer is the 8th most common cancer that occurs in most women. In a 2018 survey by Global Cancer Statistics in 185 countries of all cancer cases, 3.4% were caused by ovarian cancer. Vascular endothelial growth factor is a multifunctional cytokine that stimulates angiogenesis and increases microvascular permeability by binding to receptors located in endothelial cells in blood vessels. Immature platelet fraction (% IPF) is a modern parameter that measures young platelets and reticulation in peripheral blood. The purpose of this study was to look at differences in plasma VEGF and IPF levels between ovarian cancer sufferers and staging of ovarian cancer. This type of research is a cross sectional observational study of VEGF and Ovarian Cancer stage. A total of 18 people with ovarian cancer were sampled before surgery and after surgery an anatomy pathology examination was performed to assess early stage and advanced cancer staging. From 18 patients with ovarian cancer obtained from the early stage ovarian cancer group and advanced stage group. Obtained a median age of 50 (42-63), whereas in the advanced stage group a median age of 51 (19-68) was obtained. There is a significant difference between VEGF levels in early and advanced stage ovarian cancer with a value of p = 0,000. Using the Spearman Correlation test to assess the correlation between tumor size and VEGF levels, p values <0.001 with r = 0.742 were obtained. The conclusion of this research are advanced stage ovarian cancer VEGF is significantly higher P = 0.001 compared to early stage. Keywords: VEGF, Ovarian Cancer.


Author(s):  
Syeda Nadia Shah

One of the basic purpose of this study is to determine gender differences and relationship of violence with that of empathy and aggression. The total sample of the study contained sixty-four (N=64) University students with the age range on 20-25 years. The sample included thirty-two (n=32) male and thirty-two (n=32) female students of University of Peshawar. The results revealed the significant difference on violence between male and female university students males scored significantly higher on violence scale as compared to females. A negligible negative correlation was found between violence and empathy. It was concluded from the finding of the present study that males are more violent than females but there is no significant relation between violence, empathy and aggression.


2019 ◽  
pp. 39-55
Author(s):  
Osman Kusan ◽  
Hasan Erdem Mumcu ◽  
Abdulkerim Çeviker ◽  
Ömer Zambak ◽  
Onur Öztürk

This study was conducted to investigate the sub-scales of sports instructions of elite athletes with hearing impairment or hearing loss due to different reasons. A total of 173 hearing-impaired athletes constituted of 54 female and 119 male athletes who are active national team athletes in the age range of 15-25 years. The study was conducted based on Self Determination Theory of Deci and Ryan [9] and on the developed Sports Motivation Scale, Pelletier et al. [24] Kazak [18] applied the validity and reliability of the scale for Turkish athletes. Accordingly, since the p_values calculated for the inner motivation sub-scale and its sub-scales are less than the value of α = .05 which is taken as the level of significance, there is a statistically significant difference in the average scores of the hearing-impaired athletes in their internal motivations and sub-scales. According to gender and educational status, there was no difference in the motivation of the hearing-impaired athletes. According to the age variable, it was seen that older athletes had more external connections. Considering the general motivation scores, the athletes in tennis and swimming were less motivated than others. Elite hearing-impaired athletes are affected by both internal and external impulses. However, internal motivation scores are higher than the external. Internal motivation scores are seen as the lowest in the branch swimming area.


2021 ◽  
Vol 39 (2) ◽  
pp. 107-115
Author(s):  
Paul J. Bröckelmann ◽  
Horst Müller ◽  
Teresa Guhl ◽  
Karolin Behringer ◽  
Michael Fuchs ◽  
...  

PURPOSE We evaluated disease and treatment characteristics of patients with relapse after risk-adapted first-line treatment of early-stage, favorable, classic Hodgkin lymphoma (ES-HL). We compared second-line therapy with high-dose chemotherapy and autologous stem cell transplantation (ASCT) or conventional chemotherapy (CTx). METHODS We analyzed patients with relapse after ES-HL treated within the German Hodgkin Study Group HD10+HD13 trials. We compared, by Cox proportional hazards regression, progression-free survival (PFS) after relapse (second PFS) treated with either ASCT or CTx and performed sensitivity analyses with overall survival (OS) from relapse and Kaplan-Meier statistics. RESULTS A total of 174 patients’ disease relapsed after treatment in the HD10 (n = 53) and HD13 (n = 121) trials. Relapse mostly occurred > 12 months after first diagnosis, predominantly with stage I-II disease. Of 172 patients with known second-line therapy, 85 received CTx (49%); 70, ASCT (41%); 11, radiotherapy only (6%); and 4, palliative single agent therapies (2%). CTx was predominantly bleomycin, etoposide, doxorubicin cyclophosphamide, vincristine, procarbazine, and prednisone (BEACOPP [68%]), followed by the combination regimen of doxorubicin, bleomycin, vinblastine, and dacarbazine (19%), or other regimens (13%). Patients aged > 60 years at relapse had shorter second PFS (hazard ratio [HR], 3.0; P = .0029) and were mostly treated with CTx (n = 33 of 49; 67%) and rarely with ASCT (n = 8; 16%). After adjustment for age and a disadvantage of ASCT after the more historic HD10 trial, we did not observe a significant difference in the efficacy of CTx versus ASCT for second PFS (HR, 0.7; 95% CI, 0.3 to 1.6; P = .39). In patients in the HD13 trial who were aged ≤ 60 years, the 2-year, second PFS rate was 94.0% with CTx (95% CI, 85.7% to 100%) versus 83.3% with ASCT (95% CI, 71.8% to 94.8%). Additional sensitivity analyses including OS confirmed these observations. CONCLUSION After contemporary treatment of ES-HL, relapse mostly occurred > 12 months after first diagnosis. Polychemotherapy regimens such as BEACOPP are frequently administered and may constitute a reasonable treatment option for selected patients with relapse after ES-HL.


2020 ◽  
Vol 17 ◽  
pp. 00256
Author(s):  
Murat Baimishev ◽  
Sergey Eremin ◽  
Kirill Plemyashov ◽  
Hamidulla Baimishev ◽  
Igor Konopeltsev ◽  
...  

The purpose of the research is to determine the etiopathogenesis of reproductive dysfunction in highly productive cows. For this, one group of cows was formed on the principle of paranalogs in the amount of 37 animals inseminated in the first sexual hunt after calving, followed by taking blood samples from them using the Monovet system, considering the duration of pregnancy. During the start-up period, blood was taken 1–4 days before calving and on the first day after calving. A total of 253 blood samples were examined. Subsequently, depending on the effectiveness of insemination, animals were divided into two groups. The first group included inseminated cows after the first insemination (20 animals), the second group included 17 unfertilized cows after the first insemination. Subsequently, blood was taken from animals considering the course of childbirth and the postpartum period. Blood counts were studied according to generally accepted methods using certified equipment. The study found that at an early stage of pregnancy, cows have a significant difference in lipid metabolism and in their peroxidation, in the state of antioxidant systems compared to unstable animals. In the process of pregnancy development in cows, there is a decrease in the level of total lipids and their class, and the accumulation of products of transoxidation of lipids is reduced. In animals with retention of the placenta, a low lipid metabolism and a higher level of peroxidation were established already in the dry period. After calving, this difference increases. The obtained data can be used to develop an algorithm for the prevention of postpartum complications in cows by using substances with antioxidant properties.


Author(s):  
Dasari Tejaswini ◽  
Suhas Kulkarni ◽  
Dolar Doshi ◽  
Adepu Srilatha

AbstractBackgroundAesthetic alterations in the face can be self-perceived and can affect quality of life in young adults.ObjectiveTo assess the impact of malocclusion on self- perceived oro-facial behaviour among young adults.MethodsA Cross sectional study was conducted among 638 young adults (aged 18–21 years) of Hyderabad city. One college from each of the five zones of the Hyderabad city (five colleges) were selected by simple random sampling procedure. A 21-item Oro-facial investment scale (OFIS) questionnaire assessing self-perceived oral health knowledge, attitude, practice and Dental Aesthetic Index (DAI) assessing the severity of malocclusion was used. Data were analysed with standard statistical software (SPSS, Statistical package for the social sciences, version 20.0). p < 0.05 was considered statistically significant.ResultsMales had higher mean scores for knowledge (2.90 ± 0.49) than females (2.73 ± 0.82) and was statistically significant (p = 0.002*). No statistically significant gender differences were found in relation to attitude and practice. Analysis of variance (ANOVA) showed that there was a significant difference in all the three scores (knowledge, attitude, practice) with respect to age, with significantly high score for knowledge and practice among 18 year old subjects (p = 0.0001*; p = 0.0003* respectively) and attitude among 21 year old subjects (p = 0.0049*). No statistically significant age, gender differences were found in relation to DAI scores. Upon correlation, DAI significantly and positively correlated with knowledge (p = 0.03*) and attitude (p = 0.0001*).ConclusionThis study has shown significant impact of malocclusion on the self-perceived oro-facial behaviour.


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