scholarly journals PHARMACEUTICAL STANDARDIZATION OF PANCHAGUNA TAILA (MEDICATED OIL) AND PRODUCT DEVELOPMENT AS OINTMENT, GEL, CREAM, AND PHYSIOWAX

Author(s):  
Sweta Kumari ◽  
Dileep Singh Baghel

  Objective: The present study aimed to prepare Panchaguna taila (PGT) and its development in various dosage forms, i.e. ointment, gel, cream, and physiowax to exemplify the characteristic parameters according to pharmaceutical standards.Methods: PGT is polyherbal medicated oil used externally for treating wounds, cut, and burn and used for massaging in rheumatoid arthritis, muscular pain, sprains, and joints pain. Prepare the decoction using Haritaki, Vibhitaki, Amalaki, Nimba, Sambhalu and prepare paste (kalka) from Madhuchishta, Gandhaphiroja, Shilarasa, Rala, and Guggulu. Mix all the ingredients and heat till watery portion not evaporated from the oil with constant stirring then filter it. Add eucalyptus oil, turpentine oil, and kejoputi oil at the end and stir it well. Prepare various dosage forms like ointment, gel, cream, and physiowax using suitable base for the better and improved therapeutic application. Analytical standards for PGT such as acid value, saponification value, iodine value, and peroxide value were performed, and obtained results were appeared under the prescribed limit of the official monograph. Various physicochemical parameters such as homogeneity, spreadability, pH, and melting point were performed for PGT ointment, PGT gel, PGT cream, and PGT physiowax. Stability study of PGT was done for 3 days under the accelerated conditions.Results: In PGT, various physicochemical parameters were performed on the interval of 24, 48, and 72 hrs, and no significant variation found in their physicochemical properties when observed values were compared. PGT ointment, PGT gel, PGT cream, and PGT physiowax containing PGT as active pharmaceutical ingredient with various suitable excipients and base are easy to formulate and convenient to apply over the affected area. Rf observed between the ranges 0.21 to 0.84 as given in the standard monograph. In PGT, PGT ointment and PGT physiowax, 10 spots were found, and in PGT gel and PGT cream, 7 spots were found. 0.11, 0.15, and 0.34 spots were found in the PGT gel, PGT cream, and PGT physiowax, respectively, that can be given by the excipients or base used for their preparation.Conclusion: It is possible to make other dosage form of PGT which can be more convenient to the customers. Hence, the issues related to the PGT like staining and sticking can be resolved by developing or converting the PGT into various convenient dosages.

Author(s):  
Mr. Bade Vikas Vinayak

Abstract: In the present study herbal Hair oils were formulated. Hair is one of the vital parts of the body and a protective appendage on the body and considered accessory structure of integument along with sebaceous glands, sweat glands and nails. Hair oils are widely used by the consumer of the cosmetic industries. The hair oil samples comply for the requirements of color, odour, PH, Viscosity, Density, acid value. Present investigation was undertaken to standardize the selected herbal hair oils on physicochemical parameters and some standard. Excellent results were seen in formulation prepared by boiling method of oils preparation technique. Keyword: Herbal preparation, Hair oil, Acid value, Saponification value AIM: To Formulate & Evaluate Polyherbal Hair Oil. Objectives:  To collect information about Marketed herbal hair oils.  To prepare polyherbal hair oil.  To explore the use of Neem, Banyan tree of Arial root & Amla  To study evaluation of hair oil such as PH, Viscosity, Density, Refractive index, Acid value, Saponification value.  To achieve best formula for the hair oil using herbal ingredients.


2011 ◽  
Vol 8 (4) ◽  
pp. 1986-1992 ◽  
Author(s):  
E. O. Eddy ◽  
J. A. Ukpong ◽  
E. E. Ebenso

Oil fromTelfaria occidentalisandAnarcardium occidentalehas been extracted and characterized. The lipid content of theTelfaria occidentalisandAnarcardium occidentaliswere 58.41% and 42.15% respectively. The physicochemical parameters ofTelfaria occidentalisandAnarcardium occidentaleseeds were; boiling point; (58.90, 62.60°C), melting point; (18.50, 21.80°C), refractive index; (1.462, 1.498), specific gravity; (0.87, 0.69) saponification value; (91.16, 92.57) iodine value; (51.52, 47.20), acid value; (0.76, 3.74) ester value; (90.40, 88.87), % free fatty acid; (.38, 1.88) and peroxide value; (11.75, 15.23) respectively. Oils from these seeds were found to exhibit the needed potentials for utilization in paint and food industries and as biofuel.


INDIAN DRUGS ◽  
2018 ◽  
Vol 55 (08) ◽  
pp. 63-66
Author(s):  
S. V. Patil ◽  
◽  
V. R Aralelimath ◽  
V. A. Mahajan ◽  
N. R. Inamdar ◽  
...  

Asavas and Arishtaare alcoholic medicaments are prepared by allowing the herbal juices or their decoctions to undergo fermentation with the addition of sugar. Standardization of ayurvedic formulation is essential in order to assess the quality of drugs. In the present study standardization of asava from Syzygium cumini, known to be effective in diabetics, has been performed.Asava formulation was prepared by reported traditional method of ayurveda. Formulation has been standardized by modern scientific quality control procedure for the finished productas. Standardization of asava was achieved by organoleptic study, physicochemical parameters such as pH, specific gravity, total solid content, acid value, alcohol content, refractive index, total reducing sugars and stability study. results reveal that the physicochemical parameters were within the limits and the values could be used to establish and formulate procedures for standardization and quality controlling of these ayurvedic formulations.


2021 ◽  
Vol p5 (02) ◽  
pp. 2663-2670
Author(s):  
Deepti Negi ◽  
Anoop Kumar Singh ◽  
Vipin Kumar ◽  
Shweta G. Shukla

Having a healthy and flake free scalp is a great part of hair health. Dandruff can be a very common aliment to reduce our scalp health. If ones want to take care of his/her hair and scalp, oiling is the best thing. Herbal oils are now-a-days widely used by the people because less or no side effects. The present work was aimed to formulate Maltyadi Tail oil for antidandruff purpose (application in Hair and scalp) and was evaluated analytical study. The organoleptic parameters are appearance, color, touch and odor. The physicochemical parameters are Solubility test, Viscosity test, pH, Acid value, Peroxide value, Iodine value, Saponification value, Volatile matter, Ester value, TLC and Test for heavy / toxic metals. The result of the study showed that Maltyadi Tail fulfills all the criteria for ideal hair oil.


2019 ◽  
Author(s):  
Chem Int

The physicochemical properties of six imported and one locally produced edible vegetable oils (soybean oil, sunflower oil, sunlit oil, hayat oil, avena oil, USA vegetable oil and Niger oil) purchased from Bahir Dar city, Ethiopia, were examined for their compositional quality. All the oil samples were characterized for specific gravity, moisture content, color, relative viscosity, refractive indices, ash content, peroxide value, saponification value, smoke point, acid value, free fatty acid value and trace metals contents using established methods. The result clearly indicates that some of the oil samples exhibited unacceptable value when compared with physicochemical parameters recommended by the Codex Alimentations Commission of FAO/WHO and the specification of Ethiopian standards. The contents of nickel (Ni), copper (Cu) and iron (Fe) in seven samples were determined using ICP-OES and their concentrations were found in the range of 1.8-20.4, 45.8-82.2 and 136.04-445.0 mg/kg, respectively.


2020 ◽  
Vol 11 (4) ◽  
pp. 754-758
Author(s):  
Sangita Kamaliya ◽  
Vaghela D B ◽  
Harisha C R ◽  
Shukla V J

Background: Durvadi Ghrita is a Sneha Kalpana which is claimed to be effective in Madhumehajanya Timira (Diabetic Retinopathy).  In present study, it has been used for Nasya. Objective: Present study was planned to look out on herbal drugs used in the preparation of Durvadi Ghrita and standardization of drug by pharmacognostical and physicochemical parameters and HPTLC evaluation. Methods: Identification and authentication of all the raw drug was done by pharmacognostical study i.e. morphological characters, organoleptic characters and powder microscopy. Physicochemical evaluation and HPTLC of final product were done. Results: Pharmacognostical study of all the raw drugs of Durvadi Ghrita showed presence of oil globule, prismatic crystals of Durva. Lignified branched trichome, pollen grains of Utpala Kinjalaka. Trichome, border pitted vessels of Manjishtha. Collenchyma cells, border pitted vessel of Elvaluka. Lignified fibres, oil globules of Sita. Pitted fibres, pitted vessels of Usheera. Scalariform vessels, prismatic crystals of Musta. Pitted vessels and lignified fibres, crystal fibres of Chandana. Lignified cork, and stone cells of Padmaka etc. Pharmaceutical evaluation of Durvadi Ghrita showed results Specific Gravity 0.9125, Refractive Index 1.47, Acid Value 0.4608, Iodine Value 11.45 and Saponification Value 128.856. High Performance Thin Layer Chromatography, 12 spots were found at 254 nm and five spots were found at 366 nm. Conclusion: Identification and authentication of herbal drug used in the preparation of Durvadi Ghrita has been done. Pharmacognostical and physicochemical evaluation of prepared drug has been carried out which can be further useful for standardization of Durvadi Ghrita and other clinical researches.


2017 ◽  
Vol 41 (1) ◽  
pp. 74 ◽  
Author(s):  
Débora Silva Santos ◽  
Ilna Gomes da Silva ◽  
Maria Do Carmo Lacerda Barbosa ◽  
Maria Do Desterro Soares Brandão Nascimento ◽  
Maria Célia Pires Costa

This study aimed at the investigation of physicochemical characteristics of oils and the morphometric characteristics of fruits and seeds (almonds) of babassu (Orbignya phalerata Martius), by ecological region of the state of Maranhão. For this, samples of babassu were obtained from the following regions: Litoral, Cocais, Baixada, Cerrado and Pre-Amazonia of the state of Maranhão, and analyzed the following physicochemical parameters: acidity index, saponification index, refraction index and humidity using Analytical Standards of the Adolfo Lutz Institute. Fruits were collected from the same regions to analyze the morphometric characteristics by measuring the fruits and almonds of the studied species. The results indicate that the acidity indexes are within the maximum limit established by the ANVISA National Standard and the saponification indexes indicate the presence of medium to high molecular weight lipids. The refractometric results are in line with current standards and the moisture content was less than 1%. The lots of Orbignya phalerata Martius babassu presented a significant variability in size and weight for fruits and almonds by region.


2020 ◽  
Vol 7 (3) ◽  
pp. 581-586
Author(s):  
Aparna Yadav ◽  
◽  
Sudhakar Prasad Mishra ◽  
P. S. Kendurkar ◽  
Ajay Kumar ◽  
...  

The physiocochemical properties of Jatropha curcas kernel oils were characterized as potential biodiesel, including oil yield per plant, seed oil content, kernel oil content, acid value, iodine value, saponification value and cetane number. Twenty-five accessions of Jatropha curcas were used for oil content measurement sranging from 21.14 to 40.66 %with a mean value of 32.85% and Kernels oil 48.59 to 60.45 % with a mean value of 56.28 %. The seed index ranged significantly from a seed weight of 45.45 to 64.45 g. Oil yields per plant ranged from 0.44 to 2.85 kg with a mean value of 1.70 kg per plant, respectively. To understand the properties of acid value, iodine value, saponification and cetane number, experimental physio-chemical studies were performed. Since these properties are critical for determining the current oil condition. The current study confirms that accession seeds performed higher than international saponification value, iodine value and cetane number standards may be an important source for meeting potential energy requirements.


2021 ◽  
Vol 4 (1) ◽  
pp. 059-066
Author(s):  
Azuaga TI ◽  
Azuaga IC ◽  
Okpaegbe UC ◽  
Ibrahim AI ◽  
Manasseh CK

Soxhlet extraction of oil from seeds of Vitelleria paradoxa was carried out using n-hexane as the solvent. Standards methods were adopted in the analysis of the physiochemical properties; moisture content, melting point, total ash content, pH, specific gravity, iodine value, saponification value, acid value, free fatty acid value and ester value were all evaluated. The oil recovery rate was good with 32.6% yield, moisture content of 3.1%, melting point of 52oC and pH 5.7. Total ash content was 50.3%, specific gravity of 0.9 g/cm3, iodine value 39 mg/L, saponification value 224.6 mgKOH/g, acid value 59.9 mgKOH/g free fatty acid (FFA) 29.9 mgKOH/L and ester value 164.7 mg/L. The results shows that oil from Vitelleria paradoxa seed holds the potentials for wider applications in foods, cosmetics, pharmaceuticals, lubricants and soap making.


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