scholarly journals Development of methods for standardization of Crocus sativus (saffron) stigmas for inclusion in the draft monograph of the State Pharmacopoeia of Ukraine

2021 ◽  
Vol 19 (1(73)) ◽  
pp. 32-41
Author(s):  
O. O. Mykhailenko ◽  
A. G. Kotov ◽  
E. E. Kotova ◽  
L. M. Sira ◽  
V. M. Kovalyov ◽  
...  

Crocus sativus L. from the Iridaceae family is a medicinal and edible plant that has recently been actively cultivated in Ukraine. Saffron spice is crocus flower stigmas exhibiting a wide range of the pharmacological activity due to its three main bioactive compounds: crocin, picrocrocin and safranal. The quality of this raw material is regulatedby various normative documents, but there is no monograph in the State Pharmacopoeia of Ukraine (SPhU). Aim. To perform a comparative analysis of the monograph “Saffron for homoeopatic preparations” from the Ph. Eur. 9.0, “Saffron. Croci stigma” from the Deutscher arzneimittel codex (DAC) and “Spices – Saffron (Crocus sativus L.)” from the ISO 3632 by the following indicators: description, identifcation (microscopy and TLC), impurities, loss on drying, total ash and quantifcation of crocin, picrocrocin and safranal by UV-Vis-spectrophotometry to clarify the possibility of harmonizing the requirements of the national legal framework for Crocus stigmas withthe Ph. Eur. 9.0, DAC and ISO 3632. The results of the analysis will be taken into account in the development of the monograph of the national part of the SPhU “Crocus stigmas (saffron)”.Results and discussion. The quality indicators of Crocus stigmas and their standardization determinedby the monograph in the Ph. Eur. 9.0, DAC and ISO 3632 on the raw material studied have been analyzed; some differences in the regulated quality indicators of the raw material have been found. The results of our own research have shown that the samples of the Ukrainian Crocus (saffron) meet all these requirements. The results of the macro- and microscopic examination of the raw material are given. The chromatographic examination hasbeen performed in accordance with the Ph. Eur. 9.0 and DAC using crocin as a standard compound; the quantitative determination of crocin, picrocrocin and safranal in 8 samples of Crocus stigmas has been performed by UV-Vis-spectrophotometry in accordance with the ISO 3632. It has been proposed to introduce the following indicators to determine the specifc absorption rate: for crocin (C44H64O24; Mw – 976.70) not less than 180, for safranal (C10H14O; Mw – 150.22) – not less than 30, for picrocrocin (C16H26O7; Mw – 330.37) – not less than 60 calculated with reference to the dried raw material.Experimental part. For analysis the dried stigmas of Crocus sativus (saffron) collected in the villageLyubimivka, Kherson region, Ukraine (2016-2018), as well as commercial samples of saffron from Morocco,Azerbaijan, Spain were used. The analysis of the leading normative documents containing monographs “Crocus stigmas”, among them the Eur. Ph. 9.0, DAC and ISO 3632, was performed. The studies included description of the appearance of the whole Crocus stigmas; loss on drying and the mass fraction of volatile compounds (105 °C, 16 h); the mass fraction of total ash. The amount of picrocrocin, safranal and crocin was measured by direct reading of the absorption of 1 % aqueous solution of stigmas at 257 nm, 330 nm and 440 nm, respectively, usinga UV-Vis-spectrophotometer.Conclusions. The analysis of the requirements to quality of the medicinal raw material – stigmas of Crocus sativus – has been performed based on the monographs: “Saffron for homoeopatic preparations” from the Ph. Eur. 9.0, “Saffron. Croci stigma” from the Deutscher arzneimittel codex and “Spices – Saffron (Crocus sativus L.)” from the ISO 3632. The main criteria for standardization of the raw material have been determined. It has been proposed to introduce the monograph to the national part of the SPhU “Crocus stigmas (saffron)” according to the following requirements: identifcation (macro- and microscopic signs; thin-layer chromatography (crocin); the quantitativedetermination (the content of crocin, picrocrocin and safranal) adapted to the ISO 3632, performed by UV-Vis-spectrophotometry; impurities; loss on drying; total ash.Key words: standardization; State Pharmacopoeia of Ukraine; Crocus sativus stigma; saffron; crocin

2020 ◽  
Vol 1 (10(79)) ◽  
pp. 12-18
Author(s):  
G. Bubyreva

The existing legislation determines the education as "an integral and focused process of teaching and upbringing, which represents a socially important value and shall be implemented so as to meet the interests of the individual, the family, the society and the state". However, even in this part, the meaning of the notion ‘socially significant benefit is not specified and allows for a wide range of interpretation [2]. Yet the more inconcrete is the answer to the question – "who and how should determine the interests of the individual, the family and even the state?" The national doctrine of education in the Russian Federation, which determined the goals of teaching and upbringing, the ways to attain them by means of the state policy regulating the field of education, the target achievements of the development of the educational system for the period up to 2025, approved by the Decree of the Government of the Russian Federation of October 4, 2000 #751, was abrogated by the Decree of the Government of the Russian Federation of March 29, 2014 #245 [7]. The new doctrine has not been developed so far. The RAE Academician A.B. Khutorsky believes that the absence of the national doctrine of education presents a threat to national security and a violation of the right of citizens to quality education. Accordingly, the teacher has to solve the problem of achieving the harmony of interests of the individual, the family, the society and the government on their own, which, however, judging by the officially published results, is the task that exceeds the abilities of the participants of the educational process.  The particular concern about the results of the patriotic upbringing served as a basis for the legislative initiative of the RF President V. V. Putin, who introduced the project of an amendment to the Law of RF "About Education of the Russian Federation" to the State Duma in 2020, regarding the quality of patriotic upbringing [3]. Patriotism, considered by the President of RF V. V. Putin as the only possible idea to unite the nation is "THE FEELING OF LOVE OF THE MOTHERLAND" and the readiness for every sacrifice and heroic deed for the sake of the interests of your Motherland. However, the practicing educators experience shortfalls in efficient methodologies of patriotic upbringing, which should let them bring up citizens, loving their Motherland more than themselves. The article is dedicated to solution to this problem based on the Value-sense paradigm of upbringing educational dynasty of the Kurbatovs [15].


Author(s):  
Е.Е. Ульянченко

Исследовано влияние приема прорезания средней жилки на основные качественные показатели табачного сырья. Исследования проводили на листьях основных сортотипов табака Трапезонд и Остролист по массовым ломкам. Прорезание жилки осуществляли на инновационном оборудовании экспериментальном образце линии подготовки листьев табака к сушке ЛПТС360 (ВНИИТТИ, Краснодар). Качество табачного сырья с прорезанной жилкой определяли по товарным сортам, технологическим и курительным свойствам, химическому составу по методикам лабораторного контроля ВНИИТТИ. Инновационный способ подготовки табака к сушке в едином потоке с применением технологического оборудования, включающего прорезатель, выявил положительный технологический результат. Установлена эффективность приема прорезания средней жилки: срок естественной сушки листьев с прорезанной жилкой сократился в 2,5 раза выход 1го товарного сорта сырья составил 74,60 87,93 выход волокна сырья с прорезанной жилкой превышает минимальное значение технологических норм (75) в 1,15 1,26 раз условный расход сырья на единицу курительных изделий меньше норматива на 6 25 улучшен основной показатель химического состава табачного сырья (число Шмука) в 1,6 4,6 раза у сортотипа Трапезонд, в 1,2 1,5 раза у сортотипа Остролист дегустационные свойства сырья не ухудшились. Инновационный способ подготовки листьев табака к сушке, включающий прием прорезания средней жилки, рекомендуется для применения в производстве табачного сырья. The influence of middle vein cutting method on the main quality indicators of tobacco raw materials is studied. Studies were carried out on the leaves of the main varieties of tobacco Trapezond and Ostrolist, on mass breakdowns. Vein cutting was carried out on the innovative equipment of the line of preparation of tobacco leaves for drying LPTS360 (GNU VNIITTI RAA, Krasnodar). The quality of tobacco raw materials with a cut vein was determined by commercial grades, technological and Smoking properties, chemical composition in accordance with the methods VNIITTI. An innovative method of preparing tobacco for drying in a single stream with the use of technological equipment, including a cutter, revealed a positive technological result. The period of natural drying of leaves with cut veins decreased by 2,5 times. The yield of the 1st commercial grade of raw materials was 74,60 87,93. The output of the fiber raw material with cut vein exceeds the minimum value of technological norms (75) in 1,15 1,26 times. Conditional consumption of raw materials per unit of Smoking products is less than the norm by 6 25. The method of cutting the middle vein of the leaves improves the main indicator in the chemical composition of tobacco raw materials (Schmuck ratio) 1,6 4,6 times in the variety Trapezond and 1,2 1,5 times in the variety Ostrolist. The tasting properties of raw materials have not deteriorated. Analysis of raw material quality indicators showed that the innovative method of cutting the middle vein is effective and recommended for use in the production of tobacco raw materials.


Author(s):  
В. В. Поздняков ◽  
Ю. В. Харченко ◽  
Л. Я. Харченко ◽  
О. В. Анцыферова

Гибриды сахарной и сверхсахарной кукурузы являются хорошим сырьем для производства функциональных пищевых продуктов, в том числе диетического и детского питания. Важными показателями высокого качества этих продуктов являются повышенное содержание белка и ценного масла, незначительное количество плохо усвояемого кукурузного крахмала и высокое содержание антиоксидантов, а также отменные вкусовые качества. В работе представлены данные по оценке антиоксидантной активности большой группы новых перспективных гибридов сверхсахарной кукурузы среднеспелой группы, созданных с целью получения ценных источников сырья для консервной промышленности. Значения показателя общей антиоксидантной активности варьировали в широком интервале значений (от 31,8 % до 60,4 %, 568,4–1008 мкг/г семян), что указывает на перспективность использования этого важного биохимического параметра в селекции сверхсахарной кукурузы на качество. Hybrids of excess sugar maize are good raw material for the production of functional food products, including baby food and diet. Important indicators of high quality of these products are high protein content and a valuable oil, a small amount of poorly digestible maize starch and a high content of antioxidants, and also excellent taste qualities. The paper presents data on the evaluation of the antioxidant activity of a large group of promising new hybrids of excess sugar maize of mid-group created in order to obtain valuable raw materials for the canning industry. Index value of total antioxidant activity varied over a wide range (from 31,8 % to 60,4 %, 568,4–1,008 mg/g of seed), which indicates on promising use of this important parameter in the breeding of biochemical excess sugar maize on quality.


2021 ◽  
Vol 244 ◽  
pp. 12026
Author(s):  
Zhanna Chupina ◽  
Olga Sokolnikova ◽  
Oksana Yurchenko ◽  
Elena Ryabinina ◽  
Alena Veselko

Forecasting plays a significant role in organizing the economic activities of executive authorities using the example of customs authorities, since this is associated with the ongoing policy of optimizing customs payments administered by customs authorities, ensuring the economic security of the state, improving the quality of customs services and compliance with customs legislation. A wide range of forecasting methods allows them to be applied on the basis of assessing the feasibility of applying one method or another to forecast the main economic indicators of the activities of executive authorities. The analysis of the scientific and methodological base made it possible to form and propose a generalized algorithm for forecasting the indicators of the economic activity of executive authorities. Goal is to develop a generalized algorithm for predicting the indicators of the economic activity of executive authorities using the example of customs authorities.


Author(s):  
N. L. Naumova ◽  
E. A. Burmistrov ◽  
O. M. Burmistrova

Kefir is one of the oldest traditional fermented milk products, while it is very popular in Russia. Kefir contains mineral components, vitamins, essential amino acids, as well as several varieties of probiotic bacteria, which is so useful for health and important for nutrition. The purpose of the research was to evaluate the quality of kefir produced by the Center for the Protection of Rights (the village of Nizhnaya Sanarka, Troitsky district, Chelyabinsk region). Kefir 2.5 and 3.2 % fat content were used as an object of research. It was found that the samples of the drink under study were packed in clean, sealed bags of polymer film and in white bottles made of polyethylene terephthalate. The marking of the investigated kefir samples was incomplete (there was no sign «degree», the sign «To protect from sunlight», etc.) or incorrect (distorted terminology, numerical value of regulated quality indicators, etc.), and often - difficult to read, which violates the requirements of the state standard 51074-2003, the Technical Regulations of the Customs Union 022/2011 and 005/2011. In kefir 2.5 % fat, an excessively liquid consistency, an empty, unexpressed taste, a low acidity is detected, which indicates its immaturity and the inconsistency of quality with the current standards. The quality of kefir 3.2 % fat content complied with the requirements of the normative documents the state standard 31454-2012, the Technical Regulations of the Customs Union 033/2013. Such toxic elements as cadmium and lead in the samples of kefir were absent. According to Article 3 of the Federal Law No. 29 of 02.01.2000 «On the quality and safety of food products’ yogurt produced by the «Center for the Protection of Rights’ was recognized as improper implementation in retail trade.


Author(s):  
Oleh Tsurkan ◽  
Dmytro Prysiazhniuk ◽  
Ivan Didyk

One of the important stages of growing seeds of agricultural crops is its post-harvest processing, which includes the drying process, is the main and one of the most effective methods for storing and processing agricultural raw materials. The use of vibration drying equipment is especially effective in high-tech processes taking place in the seed industry, where product moisture is the most important condition for the implementation of technology. The object of research in this article was the technological process of post-harvest processing of high-moisture pumpkin seeds, in particular drying. The purpose of the work was to analyze the current state of post-harvest processing of high-moisture pumpkin seeds and to establish promising methods and means for intensifying this process with a simultaneous increase in the quality of the final raw material obtained. The task of the work was: to review research and publications on the state of post-harvest processing of pumpkin seeds in Ukraine, to establish the features of its post-harvest dues, in particular drying, to get acquainted with the technical means and technologies for performing the technological process of drying pumpkin seeds, to establish the main disadvantages of the existing drying equipment, to determine and to propose new promising technologies and technical solutions for intensifying the drying process of pumpkin seeds with a simultaneous increase in the quality of the final raw material with minimal energy consumption and translate them into a developed model of a vibration dryer, which sequentially implements filtration and convection stages of drying. The research methodology was based on a review analysis of existing studies and publications on the state of post-harvest treatment of pumpkin seeds in Ukraine and the search for ways to intensify this process with a simultaneous increase in the quality of the final raw material obtained. In scientific work, based on the results of the study, it was found that the existing grain drying equipment does not meet the requirements for drying high-moisture pumpkin seeds, therefore there is a need for the development, research and implementation of energy-efficient schemes and structures. The existing samples of domestic equipment for post-harvest processing of high-moisture pumpkin seeds are morally and physically obsolete, do not provide flexibility in the execution of the technological process, are energy- and metal-intensive and cannot be used in processing lots of seed material. The proposed design of a vibrating dryer, which sequentially implements filtration and convection stages of drying pumpkin seeds. The developed installation provides an intensification of this process with minimal energy consumption while increasing the quality of the final raw material obtained.


Author(s):  
И.В. Великанова ◽  
Р.А. Попов

Целью настоящей работы является оценка состояния льноводства в Российской Федерации в целом и в отдельных льносеющих регионах, выявление текущих проблем в отрасли, изучение программ государственной поддержки льняного комплекса и определение возможностей для его развития. В процессе исследования использовался широкий спектр аналитических методов изучения экономических явлений – монографический, статистический и другие. Особое внимание уделялось сопоставимости показателей для анализа динамики изучаемых процессов. Для России лён-долгунец – важнейшая техническая культура, максимально адаптированная к её почвенно-климатическим условиям, позволяющая в значительной мере обеспечить импортозамещение хлопка. Основная задача, стоящая перед льняной отраслью сегодня – создание надёжной отечественной сырьевой базы для льноперерабатывающих предприятий. От её решения зависит экономическая и стратегическая безопасность страны, которая определяется необходимостью наличия отлаженного производства отечественного волокнистого сырья и продуктов его переработки гражданского и оборонного назначения. Исследования показали, что реализуемые меры по поддержке отрасли на федеральном и региональном уровнях положительно влияют на её состояние, но пока не могут обеспечить высокую эффективность производства. Валовые сборы льноволокна не растут и стабилизировались на уровне 40 тыс. тонн, а площади посева льна-долгунца не достигают и 50 тыс. гектаров. Низким остаётся и качество льнопродукции. В условиях высокой затратности производства льнопродукции, диспаритета цен, недостаточного уровня инвестиций рентабельность производства льнопродукции довольно низка. Важными и актуальными задачами в развитии льняной отрасли являются увеличение объёмов и эффективности производства льна, повышение качества волокнистой и семенной продукции, техническая и технологическая модернизация льноводства. Поэтому, наряду с действующими программами (льготное кредитование, лизинг техники, субсидирование затрат), необходима разработка целевой комплексной программы «Развитие льняного подкомплекса региона», охватывающей не только сельскохозяйственных товаропроизводителей, но и предприятия перерабатывающей и лёгкой промышленности. The purpose of this work is to assess the state of flax cultivation in the Russian Federation as a whole and in certain flax-sowing regions, to identify current problems in the industry, to study state support programs for the flax complex and to determine opportunities for its development. A wide range of analytical methods for studying economic phenomena – monographic, statistical and others was used in the research process. Particular attention was paid to the comparability of indicators for the analysis of the dynamics of the studied processes. For Russia, the fibre flax (Linum usitatissimum) is the most important industrial crop adapted to its soil and climatic conditions as much as possible, which allows to significantly ensuring the import substitution of cotton. The main task facing the flax industry today is to create a reliable domestic raw material base for flax processing enterprises. The economic and strategic security of the country depends on its decision which is determined by the need for regular production of domestic fibrous raw materials and its derived products for civil and defense purposes. Researches have shown that the measures implemented to support the industry at the federal and regional levels positively affect its condition, but so far cannot ensure high production efficiency. Whole yields of flax fiber do not increase and have stabilized at the level of 40 thousand tons and the area of planting fibre flax (Linum usitatissimum) does not reach 50 thousand hectares. The quality of flax products remains low. In conditions of high cost of flax production, price disparity, insufficient level of investments, the profitability of flax production is rather low. Important and relevant tasks in the development of the flax industry are increasing the volume and efficiency of flax production, improving the quality of fibrous and seed products and technical and technological modernization of flax cultivation. Therefore, along with existing programs (easy credit terms, finance lease of equipment, subsidizing of costs) it is necessary to develop a targeted integral program "Development of the flax sub-complex of the region", covering not only agricultural commodity producers but also enterprises of the processing and light industries.


2020 ◽  
Vol 11 (3) ◽  
Author(s):  
V.O. Chamara ◽  
◽  
O. Yu. Strashok ◽  
O.V. Kolesnichenko ◽  
◽  
...  

Today, there is such a significant anthropogenic impact on nature all over the world that natural compensatory processes can not to deal with its harmful effects, especially in urban areas. Therefore, it is necessary to solve the current issues of urboecology and urban greening. Lawn is a multifunctional plant formation, an integral elements of urban landscapes, the basis of compositional solutions for urban greening and the main buffer element in the city. The lawn is the most important element of landscaping in any type of greenery, which plays a sanitary role. The analysis of the state of multifunctional lawns in cities and the development its ecological and biological standards for creating stable sward in urban areas is relevant. The authors present the results of the assessment of decorative effect and quality of the structure of lawn coverings for different functional purpose in the city Brovary. We chose on the territory of Brovary different lawns for multifunctional purpose: park “Peremoha”, park named after T.G. Shevchenko, park “Sosnovyi”, cemetery “Stare”, school territory № 9, boulevard “Nezalezhnosti”, stadium “Spartak”, stadium near school № 7, stadium of Brovary Higher School of Physical Culture. Determination of turf grass and weed vegetation we carried out in accordance with the “Determinant of higher plants of Ukraine” (1987). The actual weed-infested determined by the survey method and evaluated in points. For the Latin names of plants, we use The Plant List. The assessment of lawn decorative effect (general decorativeness) carried out with the 5-point scale (Laptev, 1983). We analyzed the quality of the structure of the lawn culture phytocenosis with 6-point scale of Laptev, which consists from the number of units of shoots per area of 100 cm2. Thus, we can group the experimental lawn coverings by qualitative characteristics of the state, where 5 objects from 9 experimental (park “Sosnovyi”, cemetery “Stare”, school territory № 9, boulevard “Nezalezhnosti”, stadium of Brovary Higher School of Physical Culture) evaluated in the lowest indicators and need a complete renovation. On the territory of the cemetery “Stare” lawn we found the largest number of weed species and we noted such species as: Taraxacum officinale (L.) Weber ex FH Wigg., Plantago major L., Galinsoga parviflora Cav., Capsella bursa-pastoris L. Medik., Elytrigia repens L. (Nevski), Poa annua L., Chenopodium album L., Amaranthus retroflexus L., Fallopia convolvulus (L.) Á.Löve. Indicators of the general decorativeness of lawns in the park “Peremoha” and the stadium near the school № 7 were the same, but the results of quality analysis of the structure of lawn indicate low shoot-forming ability of turf grasses, which is essential indicator for sport lawns for formation of a resistant turf to various types of loading. The lawns on the territory of park “Peremoha”, stadium “Spartak” and stadium near school № 7 characterized by good and mediocre quality of sward and require such agronomic operations as aeration, grounding and fertilization. Sport lawns in the city Brovary characterized by high indicators of weed-infested (3 points) that in turn influences both on decorative effect and complex estimation indicators of a lawn covering. It should also be noted that the frequency of fertilization for sports lawns is higher than for other types. The research results show that the lawn on the territory boulevard “Nezalezhnosti” estimated in 3 points by general decorativeness, because the projective cover was mosaic-group (Laptev, 1983) and 2 points – the quality of the structure of the lawn. In our opinion, such low rates are probably caused by anthropogenic load, as the research object located right next to the highway, but studies of this nature need to be continued. According to the results, it is established that the condition of the lawns in Brovary for different functional purpose differs greatly in quality indicators (Laptev, 1983): sports – mediocre condition, decorative – satisfactory (except for the park “Sosnovyi”), special purpose – unsatisfactory condition. The authors propose agro-technical operations to improve the quality and decorative effect of lawns in the city. However, areas of lawn coverings with "bad" grass quality indicators require restoration.


Author(s):  
G. V. Agafonov ◽  
A. E. Chusova ◽  
N. S. Kovalchuk ◽  
N. V. Zuyeva

Rye is the traditional raw material for the fermented malt production. The article considers buckwheat grains application as an unconventional raw material. The research materials were rye of Vostok 2 breed and buckwheat of Dikul breed. Amylolytic capacity (AC) of malt was determined by colorimetric iodometric method, saccharification capacity (SC) - by polarimetric method, proteolytic (PC) - by refractometric method (according to Petrov); the humidity of the samples was determined on a thermographic infrared moisture meter FD 610. The extract, acidity and color of the fermented malt was determined according to GOST R 52061-2003. It was found that AC, SC and PC of buckwheat malt are 5.8% higher, 42.9% lower and 11.6% higher respectively than those of rye malt. Comparative characteristics of fermented buckwheat and rye malts showed that there is a decrease in the mass fraction of the extract and an increase in the color of buckwheat malt. This happens due to the hydrolysis of high-molecular compounds - carbohydrates, proteins to sugars and amino acids, respectively, due to the reactions of melanoid formation, which result in improved color, taste and aroma of malt. It was found that the use of buckwheat in fermented malt technology is possible, moreover, it is a gluten-free raw material due to the low content of the gluten fraction of the protein and can be applied to a wide range of consumers, including those suffering from gluten intolerance. But to increase its extractiveness, it is desirable to use enzyme preparations at the malting stage. The novelty of the proposed technical solution is confirmed by the RF patent for invention No. 2603268 "Method for the production of fermented buckwheat malt".


2020 ◽  
Vol 164 ◽  
pp. 08017
Author(s):  
Valentina Loganina

The purpose of the work is to assess the influence of the state of the technological process of production on the error of deciding on the suitability of the batch under control. Information is provided about the values of the error of representativeness at assessing the quality of building materials using ceramic brick as an example. It is shown that the rules for acceptance of the relevant normative documents for construction products should indicate the required number of samples for testing, taking into account the probability of an error-free forecast.


Sign in / Sign up

Export Citation Format

Share Document